Product References
Alveolar macrophages from EVALI patients and e-cigarette users: a story of shifting phenotype.
Respiratory research
Warren KJ,Beck EM,Callahan SJ,Helms MN,Middleton E,Maddock S,Carr JR,Harris D,Blagev DP,Lanspa MJ,Brown SM,Paine R
Published figure using CD11c monoclonal antibody (Product # 56-0116-42) in Flow Cytometry
Sat Jun 17 00:00:00 EDT 2023
Ad26.COV2.S and SARS-CoV-2 spike protein ferritin nanoparticle vaccine protect against SARS-CoV-2 Omicron BA.5 challenge in macaques.
Cell reports. Medicine
Yu J,Thomas PV,Sciacca M,Wu C,Liu J,He X,Miller J,Hachmann NP,Surve N,McMahan K,Jacob-Dolan C,Powers O,Hall K,Barrett J,Hope D,Mazurek CR,Murdza T,Chang WC,Golub E,Rees PA,Peterson CE,Hajduczki A,Chen WH,Martinez EJ,Hussin E,Lange C,Gong H,Matyas GR,Rao M,Suthar M,Boursiquot M,Cook A,Pessaint L,Lewis MG,Andersen H,Bolton DL,Michael NL,Joyce MG,Modjarrad K,Barouch DH
56-0116-42 was used in Flow Cytometry to demonstrate that both homologous and heterologous regimens involving Ad26.COV2.S and SpFN vaccines provide robust protection against a mismatched BA.5 challenge in macaques.
Tue Apr 18 00:00:00 EDT 2023
Vaccine protection against the SARS-CoV-2 Omicron variant in macaques.
Cell
Chandrashekar A,Yu J,McMahan K,Jacob-Dolan C,Liu J,He X,Hope D,Anioke T,Barrett J,Chung B,Hachmann NP,Lifton M,Miller J,Powers O,Sciacca M,Sellers D,Siamatu M,Surve N,VanWyk H,Wan H,Wu C,Pessaint L,Valentin D,Van Ry A,Muench J,Boursiquot M,Cook A,Velasco J,Teow E,Boon ACM,Suthar MS,Jain N,Martinot AJ,Lewis MG,Andersen H,Barouch DH
56-0116-42 was used in Flow Cytometry to suggest that both humoral and cellular immune responses contribute to vaccine protection against a highly mutated SARS-CoV-2 variant.
Thu Apr 28 00:00:00 EDT 2022
Aluminum hydroxide adjuvant diverts the uptake and trafficking of genetically detoxified pertussis toxin to lysosomes in macrophages.
Molecular microbiology
Jaldin-Fincati J,Moussaoui S,Gimenez MC,Ho CY,Lancaster CE,Botelho R,Ausar F,Brookes R,Terebiznik M
Published figure using CD11c monoclonal antibody (Product # 56-0116-42) in Flow Cytometry
Sun May 01 00:00:00 EDT 2022
Upregulation of CD3ζ and L-selectin in antigen-specific cytotoxic T lymphocytes by eliminating myeloid-derived suppressor cells with doxorubicin to improve killing efficacy of neuroblastoma cells in vitro.
Journal of clinical laboratory analysis
Xu W,Li S,Li M,Zhou H,Yang X
Published figure using CD11c monoclonal antibody (Product # 56-0116-42) in Flow Cytometry
Sat Jan 01 00:00:00 EST 2022
Isolevuglandins disrupt PU.1-mediated C1q expression and promote autoimmunity and hypertension in systemic lupus erythematosus.
JCI insight
Patrick DM,de la Visitación N,Krishnan J,Chen W,Ormseth MJ,Stein CM,Davies SS,Amarnath V,Crofford LJ,Williams JM,Zhao S,Smart CD,Dikalov S,Dikalova A,Xiao L,Van Beusecum JP,Ao M,Fogo AB,Kirabo A,Harrison DG
Published figure using CD11c monoclonal antibody (Product # 56-0116-42) in Flow Cytometry
Fri Jul 08 00:00:00 EDT 2022
Holistic Characterization of Tumor Monocyte-to-Macrophage Differentiation Integrates Distinct Immune Phenotypes in Kidney Cancer.
Cancer immunology research
Mujal AM,Combes AJ,Rao AA,Binnewies M,Samad B,Tsui J,Boissonnas A,Pollack JL,Argüello RJ,Meng MV,Porten SP,Ruhland MK,Barry KC,Chan V,Krummel MF
56-0116-42 was used in Flow cytometry/Cell sorting to show that holistic analysis of monocyte-to-macrophage differentiation creates a framework for critically different immune states.
Fri Apr 01 00:00:00 EDT 2022
Low-dose Ad26.COV2.S protection against SARS-CoV-2 challenge in rhesus macaques.
Cell
He X,Chandrashekar A,Zahn R,Wegmann F,Yu J,Mercado NB,McMahan K,Martinot AJ,Piedra-Mora C,Beecy S,Ducat S,Chamanza R,Huber SR,van Heerden M,van der Fits L,Borducchi EN,Lifton M,Liu J,Nampanya F,Patel S,Peter L,Tostanoski LH,Pessaint L,Van Ry A,Finneyfrock B,Velasco J,Teow E,Brown R,Cook A,Andersen H,Lewis MG,Schuitemaker H,Barouch DH
56-0116-42 was used in Flow Cytometry to demonstrate that a single immunization with relatively low dose of Ad26.COV2.S effectively protected against SARS-CoV-2 challenge in rhesus macaques, although a higher vaccine dose may be required for protection in the upper respiratory tract.
Thu Jun 24 00:00:00 EDT 2021
IgE-Based Therapeutic Combination Enhances Antitumor Response in Preclinical Models of Pancreatic Cancer.
Molecular cancer therapeutics
Markov SD,Caffrey TC,O'Connell KA,Grunkemeyer JA,Shin S,Hanson R,Patil PP,Shukla SK,Gonzalez D,Crawford AJ,Vance KE,Huang Y,Eberle KC,Radhakrishnan P,Grandgenett PM,Singh PK,Madiyalakan R,Daniels-Wells TR,Penichet ML,Nicodemus CF,Poole JA,Jaffee EM,Hollingsworth MA,Mehla K
56-0116-42 was used in Flow cytometry/Cell sorting to demonstrate the novel tumor protective benefits of tumor antigen-specific IgE-based therapeutics in a preclinical model of pancreatic cancer, which can open new avenues for future clinical interventions.
Wed Dec 01 00:00:00 EST 2021
Increased TNF-α Initiates Cytoplasmic Vacuolization in Whole Blood Coculture with Dengue Virus.
Journal of immunology research
Satria RD,Huang TW,Jhan MK,Shen TJ,Tseng PC,Wang YT,Yang ZY,Hsing CH,Lin CF
Published figure using CD11c monoclonal antibody (Product # 56-0116-42) in Flow Cytometry
Mon Dec 06 00:00:00 EST 2021
SUMOylation disassembles the tetrameric pyruvate kinase M2 to block myeloid differentiation of leukemia cells.
Cell death & disease
Xia L,Jiang Y,Zhang XH,Wang XR,Wei R,Qin K,Lu Y
Published figure using CD11c monoclonal antibody (Product # 56-0116-42) in Flow Cytometry
Wed Jan 20 00:00:00 EST 2021
Cytomegalovirus mediates expansion of IL-15-responsive innate-memory cells with SIV killing function.
The Journal of clinical investigation
Méndez-Lagares G,Chin N,Chang WLW,Lee J,Rosás-Umbert M,Kieu HT,Merriam D,Lu W,Kim S,Adamson L,Brander C,Luciw PA,Barry PA,Hartigan-O'Connor DJ
56-0116-42 was used in Flow Cytometry /test) to investigate the effects of rhesus CMV (RhCMV) on composition and function of the immune system in young macaques.
Mon Aug 02 00:00:00 EDT 2021
The long non-coding RNA Cancer Susceptibility 15 (CASC15) is induced by isocitrate dehydrogenase (IDH) mutations and maintains an immature phenotype in adult acute myeloid leukemia.
Haematologica
Grasedieck S,Ruess C,Krowiorz K,Lux S,Pochert N,Schwarzer A,Klusmann JH,Jongen-Lavrencic M,Herold T,Bullinger L,Pollack JR,Rouhi A,Kuchenbauer F
Published figure using CD11c monoclonal antibody (Product # 56-0116-42) in Flow Cytometry
Tue Sep 01 00:00:00 EDT 2020
Human and Mouse Transcriptome Profiling Identifies Cross-Species Homology in Pulmonary and Lymph Node Mononuclear Phagocytes.
Cell reports
Leach SM,Gibbings SL,Tewari AD,Atif SM,Vestal B,Danhorn T,Janssen WJ,Wager TD,Jakubzick CV
Published figure using CD11c monoclonal antibody (Product # 56-0116-42) in Flow Cytometry
Tue Nov 03 00:00:00 EST 2020
Unleashing Type-2 Dendritic Cells to Drive Protective Antitumor CD4+ T Cell Immunity.
Cell
Binnewies M,Mujal AM,Pollack JL,Combes AJ,Hardison EA,Barry KC,Tsui J,Ruhland MK,Kersten K,Abushawish MA,Spasic M,Giurintano JP,Chan V,Daud AI,Ha P,Ye CJ,Roberts EW,Krummel MF
56-0116 was used in Flow cytometry/Cell sorting to highlight a pathway that restrains cDC2 and whose reversal enhances CD4+ Tconv abundance and controls tumor growth.
Thu Apr 18 00:00:00 EDT 2019
A natural killer-dendritic cell axis defines checkpoint therapy-responsive tumor microenvironments.
Nature medicine
Barry KC,Hsu J,Broz ML,Cueto FJ,Binnewies M,Combes AJ,Nelson AE,Loo K,Kumar R,Rosenblum MD,Alvarado MD,Wolf DM,Bogunovic D,Bhardwaj N,Daud AI,Ha PK,Ryan WR,Pollack JL,Samad B,Asthana S,Chan V,Krummel MF
56-0116 was used in Flow cytometry/Cell sorting to reveal that innate immune stimulatory dendritic cells and natural killer cells cluster together as an excellent prognostic tool for T cell-directed immunotherapy and that these innate cells are necessary for enhanced T cell tumor responses, suggesting this axis as a target for new therapies.
Wed Aug 01 00:00:00 EDT 2018
AG490 reverses phenotypic alteration of dendritic cells by bladder cancer cells.
Oncology letters
Xiu W,Ma J,Lei T,Zhang M
Published figure using CD11c monoclonal antibody (Product # 56-0116-42) in Flow Cytometry
Sat Sep 01 00:00:00 EDT 2018
Imbalance of M1/M2 macrophages is linked to severity level of knee osteoarthritis.
Experimental and therapeutic medicine
Liu B,Zhang M,Zhao J,Zheng M,Yang H
56-0116-42 was used in Flow cytometry/Cell sorting to investigate the status of M1 and M2 macrophages in knee osteoarthritis.
Sat Dec 01 00:00:00 EST 2018
CD226 opposes TIGIT to disrupt Tregs in melanoma.
JCI insight
Fourcade J,Sun Z,Chauvin JM,Ka M,Davar D,Pagliano O,Wang H,Saada S,Menna C,Amin R,Sander C,Kirkwood JM,Korman AJ,Zarour HM
56-0116 was used in Flow cytometry/Cell sorting to study if a high TIGIT/CD226 ratio in Tregs regulate their suppressive function and stability in melanoma.
Thu Jul 26 00:00:00 EDT 2018
Single-cell tracking of flavivirus RNA uncovers species-specific interactions with the immune system dictating disease outcome.
Nature communications
Douam F,Hrebikova G,Albrecht YE,Sellau J,Sharon Y,Ding Q,Ploss A
56-0116 was used in Flow cytometry/Cell sorting to demonstrate the tracking of and sense viral RNA at single-cell resolution within complex subsets of the human and murine immune system in different mouse models.
Tue Mar 14 00:00:00 EDT 2017
Resolving TYK2 locus genotype-to-phenotype differences in autoimmunity.
Science translational medicine
Dendrou CA,Cortes A,Shipman L,Evans HG,Attfield KE,Jostins L,Barber T,Kaur G,Kuttikkatte SB,Leach OA,Desel C,Faergeman SL,Cheeseman J,Neville MJ,Sawcer S,Compston A,Johnson AR,Everett C,Bell JI,Karpe F,Ultsch M,Eigenbrot C,McVean G,Fugger L
56-0116 was used in Flow cytometry/Cell sorting to reveal a protective homozygous effect that defined a signalling optimum between autoimmunity and immunodeficiency and identified TYK2 as a potential drug target for autoimmune disorders.
Wed Nov 02 00:00:00 EDT 2016
Effect of chronic morphine administration on circulating dendritic cells in SIV-infected rhesus macaques.
Journal of neuroimmunology
Cornwell WD,Wagner W,Lewis MG,Fan X,Rappaport J,Rogers TJ
56-0116 was used in Flow cytometry/Cell sorting to study the effect of chronic morphine administration on the circulating dendritic cell population dynamics associated with SIV infection.
Wed Jun 15 00:00:00 EDT 2016
Restricted dendritic cell and monocyte progenitors in human cord blood and bone marrow.
The Journal of experimental medicine
Lee J,Breton G,Oliveira TY,Zhou YJ,Aljoufi A,Puhr S,Cameron MJ,Sékaly RP,Nussenzweig MC,Liu K
56-0116 was used in Flow cytometry/Cell sorting to study the development of dendritic cells from hematopoietic stem cell progenitors using a novel culture system.
Mon Mar 09 00:00:00 EDT 2015
Towards programming immune tolerance through geometric manipulation of phosphatidylserine.
Biomaterials
Roberts RA,Eitas TK,Byrne JD,Johnson BM,Short PJ,McKinnon KP,Reisdorf S,Luft JC,DeSimone JM,Ting JP
Published figure using CD11c monoclonal antibody (Product # 56-0116-42) in Flow Cytometry
Tue Dec 01 00:00:00 EST 2015
Pharmacological targeting of miR-155 via the NEDD8-activating enzyme inhibitor MLN4924 (Pevonedistat) in FLT3-ITD acute myeloid leukemia.
Leukemia
Khalife J,Radomska HS,Santhanam R,Huang X,Neviani P,Saultz J,Wang H,Wu YZ,Alachkar H,Anghelina M,Dorrance A,Curfman J,Bloomfield CD,Medeiros BC,Perrotti D,Lee LJ,Lee RJ,Caligiuri MA,Pichiorri F,Croce CM,Garzon R,Guzman ML,Mendler JH,Marcucci G
Published figure using CD11c monoclonal antibody (Product # 56-0116-42) in Flow Cytometry
Thu Oct 01 00:00:00 EDT 2015
dNP2 is a blood-brain barrier-permeable peptide enabling ctCTLA-4 protein delivery to ameliorate experimental autoimmune encephalomyelitis.
Nature communications
Lim S,Kim WJ,Kim YH,Lee S,Koo JH,Lee JA,Yoon H,Kim DH,Park HJ,Kim HM,Lee HG,Yun Kim J,Lee JU,Hun Shin J,Kyun Kim L,Doh J,Kim H,Lee SK,Bothwell ALM,Suh M,Choi JM
Published figure using CD11c monoclonal antibody (Product # 56-0116-42) in Flow Cytometry
Tue Sep 15 00:00:00 EDT 2015
Distinct phenotype, longitudinal changes of numbers and cell-associated virus in blood dendritic cells in SIV-infected CD8-lymphocyte depleted macaques.
PloS one
Soulas C,Autissier PJ,Burdo TH,Piatak M,Lifson JD,Williams KC
56-0116 was used in Flow cytometry/Cell sorting to study the effects of SIV infection on different myeloid dendritic cell populations.
Wed Apr 27 00:00:00 EDT 2016
Breast-fed and bottle-fed infant rhesus macaques develop distinct gut microbiotas and immune systems.
Science translational medicine
Ardeshir A,Narayan NR,Méndez-Lagares G,Lu D,Rauch M,Huang Y,Van Rompay KK,Lynch SV,Hartigan-O'Connor DJ
56-0116 was used in Flow cytometry/Cell sorting to investigate how diet might shape the primate immune system, showing that breast-fed and bottle-fed infant rhesus macaques develop distinct gut microbiotas and immune systems.
Wed Sep 03 00:00:00 EDT 2014
TLR3-responsive, XCR1+, CD141(BDCA-3)+/CD8α+-equivalent dendritic cells uncovered in healthy and simian immunodeficiency virus-infected rhesus macaques.
Journal of immunology (Baltimore, Md. : 1950)
Dutertre CA,Jourdain JP,Rancez M,Amraoui S,Fossum E,Bogen B,Sanchez C,Couëdel-Courteille A,Richard Y,Dalod M,Feuillet V,Cheynier R,Hosmalin A
56-0116 was used in Flow cytometry/Cell sorting to identify nonhuman primate cells equivalent to CD8α(+) myeloid dendritic cells.
Thu May 15 00:00:00 EDT 2014
Respiratory syncytial virus G protein CX3C motif impairs human airway epithelial and immune cell responses.
Journal of virology
Chirkova T,Boyoglu-Barnum S,Gaston KA,Malik FM,Trau SP,Oomens AG,Anderson LJ
56-0116 was used in Flow cytometry/Cell sorting to elucidate the contribution of a conserved motif in the RSV G protein to the pathogenesis of the disease.
Sun Dec 01 00:00:00 EST 2013
Pivotal role of M-DC8⁺ monocytes from viremic HIV-infected patients in TNFα overproduction in response to microbial products.
Blood
Dutertre CA,Amraoui S,DeRosa A,Jourdain JP,Vimeux L,Goguet M,Degrelle S,Feuillet V,Liovat AS,Müller-Trutwin M,Decroix N,Deveau C,Meyer L,Goujard C,Loulergue P,Launay O,Richard Y,Hosmalin A
56-0116 was used in Flow cytometry/Cell sorting to investigate the numbers and TNFα production of fully defined circulating dendritic cell and monocyte populations during HIV-1 infection.
Thu Sep 13 00:00:00 EDT 2012
Targeting CDK1 promotes FLT3-activated acute myeloid leukemia differentiation through C/EBPα.
The Journal of clinical investigation
Radomska HS,Alberich-Jordà M,Will B,Gonzalez D,Delwel R,Tenen DG
Published figure using CD11c monoclonal antibody (Product # 56-0116-42) in Flow Cytometry
Wed Aug 01 00:00:00 EDT 2012
