Invitrogen

CD184 (CXCR4) Monoclonal Antibody (2B11), eBioscience™

Advanced Verification

This Antibody was verified by Knockdown to ensure that the antibody binds to the antigen stated.

17 Published Figures

35 References

View all (70) CXCR4 (CD184) antibodies

Datasheet

Protocols

Questions & Answers

Tech Support

Datasheet

Protocols

Questions & Answers

Tech Support

CD184 (CXCR4) Antibody in Western Blot (WB)

FIGURE: 1 / 21

CD184 (CXCR4) Antibody (14-9991-82) in WB

Western blot was performed using Anti-CD184 (CXCR4) Monoclonal Antibody (2B11), eBioscience™ (Product # 14-9991-82) and 40-100 kDa band corresponding to CD184 (CXCR4) was observed across all the cell lines. Whole cell extracts (30 µg lysate) of HeLa (Lane 1), Jurkat (Lane 2), HT-29 (Lane 3) were electrophoresed using NuPAGE™ 4-12% Bis-Tris Protein Gel (Product # NP0321BOX), 10 well. Resolved proteins were then transferred onto a nitrocellulose membrane (Product # IB23001) by iBlot® 2 Dry Blotting System (Product # IB21001). The blot was pr... View More

CD184 (CXCR4) Antibody in Flow Cytometry (Flow)

CD184 (CXCR4) Antibody in Immunocytochemistry (ICC/IF)

Product Image Gallery

Product Details

14-9991-82

Applications

Tested Dilution

Publications

Western Blot (WB)

1:1,000

View 2 publications 2 publications

Immunohistochemistry (IHC)

View 1 publication 1 publication

Immunohistochemistry (Frozen) (IHC (F))

Assay-Dependent

Immunocytochemistry (ICC/IF)

View 4 publications 4 publications

Flow Cytometry (Flow)

1 µg/test

View 28 publications 28 publications

Product Specifications

Species Reactivity

Human, Mouse

Published species

Human, Mouse

Host/Isotype

Rat / IgG2b, kappa

Class

Monoclonal

Type

Antibody

Clone

2B11

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

0.5 mg/mL

Purification

Affinity chromatography

Storage buffer

PBS, pH 7.2

Contains

0.09% sodium azide

Storage conditions

4° C

Shipping conditions

Ambient (domestic); Wet ice (international)

RRID

AB_842770

Product Specific Information

Description: The 2B11 monoclonal antibody reacts with mouse and human CXCR4, also known as CD184, Fusin, LESTR, or HUMSTR. Fusin is a member of the G-protein-coupled chemokine receptor family with seven membrane-spanning domains, and functions as a coreceptor for X4 HIV-1 entry into CD4+ cells. In addition it has been shown to play a role in lymphocyte migration. The ligand for CXCR4 is SDF1. CXCR4 is required for maintenance of granulocyte progenitors in the bone marrow and essential for B cell development. Expression of CXCR4 is different between mice and human. In the thymus CXCR4 is restricted to CD4+CD8+ cells while in the spleen predominant expression is found on B lymphocytes.

The monoclonal antibody 2B11 recognizes the amino terminus of CXCR4 and has been reported to have functional activity; it does not block SDF1a but causes internalization of the receptor.

Applications Reported: This 2B11 antibody has been reported for use in flow cytometric analysis, immunoblotting (WB), and immunohistology staining of frozen tissue sections.

Applications Tested: This 2B11 antibody has been tested by flow cytometric analysis of mouse thymocytes. This can be used at less than or equal to 1 µg per test. A test is defined as the amount (µg) of antibody that will stain a cell sample in a final volume of 100 µL. Cell number should be determined empirically but can range from 10^5 to 10^8 cells/test. It is recommended that the antibody be carefully titrated for optimal performance in the assay of interest.

Purity: Greater than 90%, as determined by SDS-PAGE.

Aggregation: Less than 10%, as determined by HPLC.

Filtration: 0.2 µm post-manufacturing filtered.

Target Information

CXCR4 (Fusin, LESTR, HUMSTR) is a member of the G-protein-coupled chemokine receptor family with seven membrane-spanning domains, and functions as a co-receptor for X4 HIV-1 entry into CD4+ cells. CXCR4 has been proved to be the co-receptor for HIV-2's binding to CD4 through envelope glycoprotein gp 120 and promotes Env-mediated fusion of the virus. In other cases, CXCR4 can even function as the only receptor for HIV-2's binding to the CD4 host cells. CXCR4 is the receptor for the C-X-C chemokine CXCL12/SDF-1 that transduces a signal by increasing intracellular calcium ion levels and enhancing MAPK1/MAPK3 activation. CXCR4 acts as a receptor for extracellular ubiquitin; leading to enhanced intracellular calcium ions and reduced cellular cAMP levels. Also, CXCR4 is involved in hematopoiesis and in cardiac ventricular septum formation, and plays an essential role in vascularization of the gastrointestinal tract, probably by regulating vascular branching and/or remodeling processes in endothelial cells. In the CNS, CXCR4 could mediate hippocampal-neuron survival and is involved in cerebellar development. CXCR4 binds bacterial lipopolysaccharide (LPS) and mediates LPS-induced inflammatory response, including TNF secretion by monocytes. Antibodies to CXCR4 block HIV-1 and HIV-2 fusion and infection of human target cells. The amino-terminal domain and the second extracellular loop of CXCR4 serve as HIV biding sites.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

Product References

Designing Synthetic, Sulfated Glycosaminoglycan Mimetics That Are Orally Bioavailable and Exhibiting In Vivo Anticancer Activity.

Journal of medicinal chemistry

Morla S,Ravikumar O,O'Hara C,Boothello R,Vera A,Abdelfadiel EI,Fayyad R,Afosah DK,Sharon C,Fernandez L,Shah SA,Patel BB,Desai UR

Published figure using CD184 (CXCR4) monoclonal antibody (Product # 14-9991-82) in Flow Cytometry

Thu Jan 26 00:00:00 EST 2023

PHGDH is required for germinal center formation and is a therapeutic target in MYC-driven lymphoma.

The Journal of clinical investigation

D'Avola A,Legrave N,Tajan M,Chakravarty P,Shearer RL,King HW,Kluckova K,Cheung EC,Clear AJ,Gunawan AS,Zhang L,James LK,MacRae JI,Gribben JG,Calado DP,Vousden KH,Riches JC

Published figure using CD184 (CXCR4) monoclonal antibody (Product # 14-9991-82) in Flow Cytometry

Mon May 02 00:00:00 EDT 2022

Mobilization-based chemotherapy-free engraftment of gene-edited human hematopoietic stem cells.

Cell

Omer-Javed A,Pedrazzani G,Albano L,Ghaus S,Latroche C,Manzi M,Ferrari S,Fiumara M,Jacob A,Vavassori V,Nonis A,Canarutto D,Naldini L

14-9991-82 was used in Flow Cytometry, Immunohistochemistry (Frozen), Western Blot to provide a potentially valuable strategy paving the way to broader and safer use of HSPC-GT.

Thu Jun 23 00:00:00 EDT 2022

Smc3 dosage regulates B cell transit through germinal centers and restricts their malignant transformation.

Nature immunology

Rivas MA,Meydan C,Chin CR,Challman MF,Kim D,Bhinder B,Kloetgen A,Viny AD,Teater MR,McNally DR,Doane AS,Béguelin W,Fernández MTC,Shen H,Wang X,Levine RL,Chen Z,Tsirigos A,Elemento O,Mason CE,Melnick AM

Published figure using CD184 (CXCR4) monoclonal antibody (Product # 14-9991-82) in Flow Cytometry

Mon Feb 01 00:00:00 EST 2021

Dual role for CXCL12 signaling in semilunar valve development.

Cell reports

Ridge LA,Kewbank D,Schütz D,Stumm R,Scambler PJ,Ivins S

14-9991-82 was used in Immunocytochemistry to investigate if CXCL12 signaling via its receptor CXCR4 fulfills distinct roles at different stages of semilunar valves development.

Tue Aug 24 00:00:00 EDT 2021

SARS-CoV-2 mRNA Vaccines Foster Potent Antigen-Specific Germinal Center Responses Associated with Neutralizing Antibody Generation.

Immunity

Lederer K,Castaño D,Gómez Atria D,Oguin TH,Wang S,Manzoni TB,Muramatsu H,Hogan MJ,Amanat F,Cherubin P,Lundgreen KA,Tam YK,Fan SHY,Eisenlohr LC,Maillard I,Weissman D,Bates P,Krammer F,Sempowski GD,Pardi N,Locci M

Published figure using CD184 (CXCR4) monoclonal antibody (Product # 14-9991-82) in Flow Cytometry

Tue Dec 15 00:00:00 EST 2020

Inhibition of Migration, Invasion and Drug Resistance of Pancreatic Adenocarcinoma Cells - Role of Snail, Slug and Twist and Small Molecule Inhibitors.

OncoTargets and therapy

Kaşıkcı E,Aydemir E,Bayrak ÖF,Şahin F

Published figure using CD184 (CXCR4) monoclonal antibody (Product # 14-9991-82) in Flow Cytometry

Fri May 20 00:00:00 EDT 2022

A Subset of Type I Conventional Dendritic Cells Controls Cutaneous Bacterial Infections through VEGFα-Mediated Recruitment of Neutrophils.

Immunity

Janela B,Patel AA,Lau MC,Goh CC,Msallam R,Kong WT,Fehlings M,Hubert S,Lum J,Simoni Y,Malleret B,Zolezzi F,Chen J,Poidinger M,Satpathy AT,Briseno C,Wohn C,Malissen B,Murphy KM,Maini AA,Vanhoutte L,Guilliams M,Vial E,Hennequin L,Newell E,Ng LG,Musette P,Yona S,Hacini-Rachinel F,Ginhoux F

14-9991 was used in Flow cytometry/Cell sorting to show that skin cDC1s are essential regulators of the innate response in cutaneous immunity and have roles beyond classical antigen presentation.

Tue Apr 16 00:00:00 EDT 2019

VLA-4 phosphorylation during tumor and immune cell migration relies on its coupling to VEGFR2 and CXCR4 by syndecan-1.

Journal of cell science

Jung O,Beauvais DM,Adams KM,Rapraeger AC

14-9991 was used in Western Blotting to demonstrate that VEGFR2 acts as a scaffold for the entire machinery necessary for phosphorylation of VLA-4 on S988.

Mon Oct 28 00:00:00 EDT 2019

Enhanced germinal center reaction by targeting vaccine antigen to major histocompatibility complex class II molecules.

NPJ vaccines

Andersen TK,Huszthy PC,Gopalakrishnan RP,Jacobsen JT,Fauskanger M,Tveita AA,Grødeland G,Bogen B

Published figure using CD184 (CXCR4) monoclonal antibody (Product # 14-9991-82) in Flow Cytometry

Thu Oct 05 00:00:00 EDT 2023

Co-infection with Chikungunya virus alters trafficking of pathogenic CD8⁺ T cells into the brain and prevents Plasmodium-induced neuropathology.

EMBO molecular medicine

Teo TH,Howland SW,Claser C,Gun SY,Poh CM,Lee WW,Lum FM,Ng LF,Rénia L

14-9991 was used in Immunohistochemistry to study the effects of Chikungunya virus co-infection on the severity and susceptibility of malaria infection.

Mon Jan 01 00:00:00 EST 2018

Precardiac organoids form two heart fields via Bmp/Wnt signaling.

Nature communications

Andersen P,Tampakakis E,Jimenez DV,Kannan S,Miyamoto M,Shin HK,Saberi A,Murphy S,Sulistio E,Chelko SP,Kwon C

Published figure using CD184 (CXCR4) monoclonal antibody (Product # 14-9991-82) in Immunofluorescence

Tue Aug 07 00:00:00 EDT 2018

CCL3 Promotes Germinal Center B Cells Sampling by Follicular Regulatory T Cells in Murine Lymph Nodes.

Frontiers in immunology

Benet ZL,Marthi M,Ke F,Wu R,Turner JS,Gabayre JB,Ivanitskiy MI,Sethi SS,Grigorova IL

14-9991 was used in Flow cytometry/Cell sorting to suggest that CCL3 facilitates direct interactions of foreign antigen-specific GC B cells and their negative regulation with Tfr cells in vivo.

Mon Sep 30 00:00:00 EDT 2019

B Cell Receptor Crosslinking Augments Germinal Center B Cell Selection when T Cell Help Is Limiting.

Cell reports

Turner JS,Ke F,Grigorova IL

14-9991 was used in Flow cytometry/Cell sorting to investigate how T cells influence germinal center B cell expansion and plasmablast formation.

Tue Nov 06 00:00:00 EST 2018

LRCH1 interferes with DOCK8-Cdc42-induced T cell migration and ameliorates experimental autoimmune encephalomyelitis.

The Journal of experimental medicine

Xu X,Han L,Zhao G,Xue S,Gao Y,Xiao J,Zhang S,Chen P,Wu ZY,Ding J,Hu R,Wei B,Wang H

14-9991 was used in Flow cytometry/Cell sorting to demonstrate LRCH1 as a novel effector to restrain PKCα-DOCK8-Cdc42 module-induced T cell migration and ameliorate EAE.

Sun Jan 01 00:00:00 EST 2017

IL-1β-induces NF-κB and upregulates microRNA-372 to inhibit spinal cord injury recovery.

Journal of neurophysiology

Zhou W,Yuan T,Gao Y,Yin P,Liu W,Pan C,Liu Y,Yu X

14-9991 was used in Flow cytometry/Cell sorting to study the role of miR-372 in inflammatory signalling in spinal cord injury.

Thu Jun 01 00:00:00 EDT 2017

A Functional Bioluminescent Zebrafish Screen for Enhancing Hematopoietic Cell Homing.

Stem cell reports

Astuti Y,Kramer AC,Blake AL,Blazar BR,Tolar J,Taisto ME,Lund TC

Published figure using CD184 (CXCR4) monoclonal antibody (Product # 14-9991-82) in Flow Cytometry

Tue Jan 10 00:00:00 EST 2017

mTOR has distinct functions in generating versus sustaining humoral immunity.

The Journal of clinical investigation

Jones DD,Gaudette BT,Wilmore JR,Chernova I,Bortnick A,Weiss BM,Allman D

14999182 was used in flow cytometry to investigate the role of mTOR in plasma cell differentiation and antibody production in RAPTOR deficient cells.

Tue Nov 01 00:00:00 EDT 2016

Expression of HIV-1 matrix protein p17 and association with B-cell lymphoma in HIV-1 transgenic mice.

Proceedings of the National Academy of Sciences of the United States of America

Carroll VA,Lafferty MK,Marchionni L,Bryant JL,Gallo RC,Garzino-Demo A

14999182 was used in flow cytometry to identify a role for HIV p17 in the development of leukemia/lymphoma

Tue Nov 15 00:00:00 EST 2016

G-CSF and Neutrophils Are Nonredundant Mediators of Murine Experimental Autoimmune Uveoretinitis.

The American journal of pathology

Goldberg GL,Cornish AL,Murphy J,Pang ES,Lim LL,Campbell IK,Scalzo-Inguanti K,Chen X,McMenamin PG,Maraskovsky E,McKenzie BS,Wicks IP

14999182 was used in flow cytometry to determine the role of G-CSF in a murine model of human uveitis-experimental autoimmune uveoretinitis

Fri Jan 01 00:00:00 EST 2016

NK Cell Maturation and Cytotoxicity Are Controlled by the Intramembrane Aspartyl Protease SPPL3.

Journal of immunology (Baltimore, Md. : 1950)

Hamblet CE,Makowski SL,Tritapoe JM,Pomerantz JL

14-9991 was used in Flow cytometry/Cell sorting to investigate the role of SPPL3 in murine NK cell biology.

Tue Mar 15 00:00:00 EDT 2016

Induced Pluripotent Stem Cells derived Muscle Progenitors Effectively Mitigate Muscular Dystrophy through Restoring the Dystrophin Distribution.

Journal of stem cell research & therapy

Cai WF,Huang W,Wang L,Wang JP,Zhang L,Ashraf M,Wu S,Wang Y

Published figure using CD184 (CXCR4) monoclonal antibody (Product # 14-9991-82) in Flow Cytometry

Wed Sep 30 00:00:00 EDT 2020

Optochemokine Tandem for Light-Control of Intracellular Ca2.

PloS one

Feldbauer K,Schlegel J,Weissbecker J,Sauer F,Wood PG,Bamberg E,Terpitz U

Published figure using CD184 (CXCR4) monoclonal antibody (Product # 14-9991-82) in Western Blot

Tue Jun 20 00:00:00 EDT 2017

Optochemokine Tandem for Light-Control of Intracellular Ca2.

PloS one

Feldbauer K,Schlegel J,Weissbecker J,Sauer F,Wood PG,Bamberg E,Terpitz U

Published figure using CD184 (CXCR4) monoclonal antibody (Product # 14-9991-82) in Western Blot

Tue Jun 20 00:00:00 EDT 2017

Optochemokine Tandem for Light-Control of Intracellular Ca2.

PloS one

Feldbauer K,Schlegel J,Weissbecker J,Sauer F,Wood PG,Bamberg E,Terpitz U

Published figure using CD184 (CXCR4) monoclonal antibody (Product # 14-9991-82) in Western Blot

Tue Jun 20 00:00:00 EDT 2017

Optochemokine Tandem for Light-Control of Intracellular Ca2.

PloS one

Feldbauer K,Schlegel J,Weissbecker J,Sauer F,Wood PG,Bamberg E,Terpitz U

Published figure using CD184 (CXCR4) monoclonal antibody (Product # 14-9991-82) in Western Blot

Tue Jun 20 00:00:00 EDT 2017

Non-canonical antagonism of PI3K by the kinase Itpkb delays thymocyte β-selection and renders it Notch-dependent.

eLife

Westernberg L,Conche C,Huang YH,Rigaud S,Deng Y,Siegemund S,Mukherjee S,Nosaka L,Das J,Sauer K

14-9991 was used in Flow cytometry/Cell sorting to elucidate the mechanisms underlying the establishment of the Notch-dependent nature of β-selection.

Thu Feb 11 00:00:00 EST 2016

Inhibition of insulin-like growth factor receptor/AKT/mammalian target of rapamycin axis targets colorectal cancer stem cells by attenuating mevalonate-isoprenoid pathway in vitro and in vivo.

Oncotarget

Sharon C,Baranwal S,Patel NJ,Rodriguez-Agudo D,Pandak WM,Majumdar AP,Krystal G,Patel BB

Published figure using CD184 (CXCR4) monoclonal antibody (Product # 14-9991-82) in Flow Cytometry

Sat Jun 20 00:00:00 EDT 2015

Intravenous transplantation of very small embryonic like stem cells in treatment of diabetes mellitus.

Avicenna journal of medical biotechnology

Abouzaripour M,Ragerdi Kashani I,Pasbakhsh P,Atlasy N

Published figure using CD184 (CXCR4) monoclonal antibody (Product # 14-9991-82) in Flow Cytometry

Thu Apr 30 00:00:00 EDT 2015

Inhibition of ER stress-associated IRE-1/XBP-1 pathway reduces leukemic cell survival.

The Journal of clinical investigation

Tang CH,Ranatunga S,Kriss CL,Cubitt CL,Tao J,Pinilla-Ibarz JA,Del Valle JR,Hu CC

14-9991 was used in Flow cytometry/Cell sorting to investigate the role of ER stress response in chronic lymphocytic leukaemia, showing that inhibition of ER stress-associated IRE-1/XBP-1 pathway reduces leukemic cell survival.

Sun Jun 01 00:00:00 EDT 2014

Regulation of germinal center responses and B-cell memory by the chromatin modifier MOZ.

Proceedings of the National Academy of Sciences of the United States of America

Good-Jacobson KL,Chen Y,Voss AK,Smyth GK,Thomas T,Tarlinton D

14-9991 was used in Flow cytometry/Cell sorting to provide evidence that manipulating epigenetic modifiers can regulate fate decisions during humoral responses.

Tue Jul 01 00:00:00 EDT 2014

Macrophage migration inhibitory factor triggers chemotaxis of CD74+CXCR2+ NKT cells in chemically induced IFN-γ-mediated skin inflammation.

Journal of immunology (Baltimore, Md. : 1950)

Hsieh CY,Chen CL,Lin YS,Yeh TM,Tsai TT,Hong MY,Lin CF

14-9991 was used in Flow cytometry/Cell sorting to hypothesize that MIF triggers an initial step in the chemotaxis of IFN-γ-producing cells in chemically induced skin inflammation.

Wed Oct 01 00:00:00 EDT 2014

Fibrocytes in the fibrotic lung: altered phenotype detected by flow cytometry.

Frontiers in pharmacology

Reese C,Lee R,Bonner M,Perry B,Heywood J,Silver RM,Tourkina E,Visconti RP,Hoffman S

Published figure using CD184 (CXCR4) monoclonal antibody (Product # 14-9991-82) in Flow Cytometry

Mon Jul 07 00:00:00 EDT 2014

Sequential desensitization of CXCR4 and S1P5 controls natural killer cell trafficking.

Blood

Mayol K,Biajoux V,Marvel J,Balabanian K,Walzer T

14-9991 was used in Flow cytometry/Cell sorting to investigate the role of CXCR4 and S1P5 in natural killer cell trafficking.

Thu Nov 03 00:00:00 EDT 2011

Intramuscular VEGF activates an SDF1-dependent progenitor cell cascade and an SDF1-independent muscle paracrine cascade for cardiac repair.

American journal of physiology. Heart and circulatory physiology

Zisa D,Shabbir A,Mastri M,Taylor T,Aleksic I,McDaniel M,Suzuki G,Lee T

Published figure using CD184 (CXCR4) monoclonal antibody (Product # 14-9991-82) in Immunofluorescence

Thu Dec 01 00:00:00 EST 2011

Intramuscular VEGF activates an SDF1-dependent progenitor cell cascade and an SDF1-independent muscle paracrine cascade for cardiac repair.

American journal of physiology. Heart and circulatory physiology

Zisa D,Shabbir A,Mastri M,Taylor T,Aleksic I,McDaniel M,Suzuki G,Lee T

Published figure using CD184 (CXCR4) monoclonal antibody (Product # 14-9991-82) in Immunofluorescence

Thu Dec 01 00:00:00 EST 2011

Intramuscular VEGF repairs the failing heart: role of host-derived growth factors and mobilization of progenitor cells.

American journal of physiology. Regulatory, integrative and comparative physiology

Zisa D,Shabbir A,Mastri M,Suzuki G,Lee T

Published figure using CD184 (CXCR4) monoclonal antibody (Product # 14-9991-82) in Flow Cytometry

Sun Nov 01 00:00:00 EDT 2009

Bioinformatics

Protein Aliases: C Cmotif chemokine; C X C motif chemokine; C-X-C chemokine receptor type 4; CC motif chemokine; CCmotif chemokine; CD antigen CD184; CD184; CD184 antigen; chemokine (C-X-C motif) receptor 4; chemokine (C-X-C) receptor 4; chemokine receptor; chemokine receptor 4; CXC; CXC motif chemokine; CXC-R4; CXCR-4; FB22; Fusin; HM89; HUMSTR; LAP-3; LCR1; LESTR; Leukocyte-derived seven transmembrane domain receptor; leukocyte-expressed seven-transmembrane-domain; Lipopolysaccharide-associated protein 3; LPS-associated protein 3; neuropeptide Y receptor Y3; neuropeptide Y3 receptor; NPYRL; PB-CKR; Pre-B-cell-derived chemokine receptor; SDF-1 receptor; seven transmembrane helix receptor; seven-transmembrane-segment receptor, spleen; Stromal cell-derived factor 1 receptor

View more View less

Gene Aliases: b2b220Clo; CD184; Cmkar4; CXCR4; D2S201E; FB22; HM89; HSY3RR; LAP-3; LAP3; LCR1; LESTR; NPY3R; NPYR; NPYRL; NPYY3R; PB-CKR; PBSF/SDF-1; Sdf1r; WHIM; WHIMS

View more View less

UniProt ID: (Human) P61073, (Mouse) P70658

View more View less

Entrez Gene ID: (Human) 7852, (Mouse) 12767

View more View less

Function(s)

virus receptor activity actin binding G-protein coupled receptor activity protein binding drug binding coreceptor activity C-X-C chemokine receptor activity cytokine binding ubiquitin protein ligase binding myosin light chain binding ubiquitin binding signal transducer activity chemokine receptor activity

Process(es)

patterning of blood vessels ameboidal-type cell migration neuron migration epithelial cell development chemotaxis signal transduction G-protein coupled receptor signaling pathway germ cell development nervous system development brain development motor neuron axon guidance germ cell migration organ morphogenesis cell migration calcium-mediated signaling telencephalon cell migration regulation of cell migration T cell proliferation neutrophil activation regulation of programmed cell death myelin maintenance positive regulation of oligodendrocyte differentiation regulation of chemotaxis regulation of calcium ion transport cardiac muscle contraction chemokine-mediated signaling pathway cellular response to cytokine stimulus activation of MAPK activity response to hypoxia dendritic cell chemotaxis apoptotic process inflammatory response positive regulation of cytosolic calcium ion concentration neuron recognition response to virus fusion of virus membrane with host plasma membrane entry into host cell

Performance Guarantee

If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*

Learn more

CD184 (CXCR4) Monoclonal Antibody (2B11), eBioscience™

CD184 (CXCR4) Antibody (14-9991-82) in WB

Product Details

14-9991-82

Western Blot (WB)

Immunohistochemistry (IHC)

Immunohistochemistry (Frozen) (IHC (F))

Immunocytochemistry (ICC/IF)

Flow Cytometry (Flow)

Species Reactivity

Published species

Host/Isotype

Class

Type

Clone

Conjugate

Form

Concentration

Purification

Storage buffer

Contains

Storage conditions

Shipping conditions

RRID

Product Specific Information

Target Information

Bioinformatics

Performance Guarantee

We're here to help

Your items have has been added!