Product References
CD153/CD30 signaling promotes age-dependent tertiary lymphoid tissue expansion and kidney injury.
The Journal of clinical investigation
Sato Y,Oguchi A,Fukushima Y,Masuda K,Toriu N,Taniguchi K,Yoshikawa T,Cui X,Kondo M,Hosoi T,Komidori S,Shimizu Y,Fujita H,Jiang L,Kong Y,Yamanashi T,Seita J,Yamamoto T,Toyokuni S,Hamazaki Y,Hattori M,Yoshikai Y,Boor P,Floege J,Kawamoto H,Murakawa Y,Minato N,Yanagita M
Published figure using CD279 (PD-1) monoclonal antibody (Product # 11-9985-82) in Flow Cytometry
Tue Jan 18 00:00:00 EST 2022
CD4+ CTLs Act as a Key Effector Population for Allograft Rejection of MSCs in a Donor MHC-II Dependent Manner in Injured Liver.
Aging and disease
Shen S,Li Y,Jin M,Fan D,Pan R,Lin A,Chen Y,Xiang L,Zhao RC,Shao J
Published figure using CD279 (PD-1) monoclonal antibody (Product # 11-9985-82) in Flow Cytometry
Thu Dec 01 00:00:00 EST 2022
Ultrasound combined with nanobubbles promotes systemic anticancer immunity and augments anti-PD1 efficacy.
Journal for immunotherapy of cancer
Hu J,He J,Wang Y,Zhao Y,Fang K,Dong Y,Chen Y,Zhang Y,Zhang C,Wang H,Tan J,Wang J,Zi R,Liu C,Liang H,Guo Y,Ou J
Published figure using CD279 (PD-1) monoclonal antibody (Product # 11-9985-82) in Flow Cytometry
Tue Mar 01 00:00:00 EST 2022
PRDM1/BLIMP1 induces cancer immune evasion by modulating the USP22-SPI1-PD-L1 axis in hepatocellular carcinoma cells.
Nature communications
Li Q,Zhang L,You W,Xu J,Dai J,Hua D,Zhang R,Yao F,Zhou S,Huang W,Dai Y,Zhang Y,Baheti T,Qian X,Pu L,Xu J,Xia Y,Zhang C,Tang J,Wang X
Published figure using CD279 (PD-1) monoclonal antibody (Product # 11-9985-82) in Flow Cytometry
Mon Dec 12 00:00:00 EST 2022
Mobilizing phospholipids on tumor plasma membrane implicates phosphatidylserine externalization blockade for cancer immunotherapy.
Cell reports
Wang W,Wu S,Cen Z,Zhang Y,Chen Y,Huang Y,Cillo AR,Prokopec JS,Quarato G,Vignali DAA,Stewart-Ornstein J,Li S,Lu B,Gong YN
Published figure using CD279 (PD-1) monoclonal antibody (Product # 11-9985-82) in Flow Cytometry
Tue Nov 01 00:00:00 EDT 2022
The long multi-epitope peptide vaccine combined with adjuvants improved the therapeutic effects in a glioblastoma mouse model.
Frontiers in immunology
Tran TA,Kim YH,Kim GE,Jung S,Kim IY,Moon KS,Kim YJ,Lee TK,Yun H,Lee JJ,Lee HJ,Lee CW,Jung TY
11-9985-82 was used in Flow cytometry/Cell sorting to show that long multi-epitope peptides composed of MHCI peptides, BIRC5 and EphA2, and the MHCII peptide, PADRE, in combination with lenalidomide and anti-PD1 has the potential to improve the therapeutic effects of a vaccine against GBM.
Tue Nov 29 00:00:00 EST 2022
NF-κB-inducing kinase maintains T cell metabolic fitness in antitumor immunity.
Nature immunology
Gu M,Zhou X,Sohn JH,Zhu L,Jie Z,Yang JY,Zheng X,Xie X,Yang J,Shi Y,Brightbill HD,Kim JB,Wang J,Cheng X,Sun SC
11-9985-82 was used in Flow cytometry to establish NIK as a pivotal regulator of T cell metabolism and highlight a post-translational mechanism of metabolic regulation.
Mon Feb 01 00:00:00 EST 2021
NF-κB-inducing kinase maintains T cell metabolic fitness in antitumor immunity.
Nature immunology
Gu M,Zhou X,Sohn JH,Zhu L,Jie Z,Yang JY,Zheng X,Xie X,Yang J,Shi Y,Brightbill HD,Kim JB,Wang J,Cheng X,Sun SC
11-9985-82 was used in Flow cytometry to establish NIK as a pivotal regulator of T cell metabolism and highlight a post-translational mechanism of metabolic regulation.
Mon Feb 01 00:00:00 EST 2021
A unified atlas of CD8 T cell dysfunctional states in cancer and infection.
Molecular cell
Pritykin Y,van der Veeken J,Pine AR,Zhong Y,Sahin M,Mazutis L,Pe'er D,Rudensky AY,Leslie CS
11-9985-82 was used in Flow cytometry/Cell sorting to show that our atlas of CD8 T cell states will facilitate mechanistic studies of T cell immunity and translational efforts.
Thu Jun 03 00:00:00 EDT 2021
NEO100 enables brain delivery of blood‒brain barrier impermeable therapeutics.
Neuro-oncology
Wang W,Marín-Ramos NI,He H,Zeng S,Cho HY,Swenson SD,Zheng L,Epstein AL,Schönthal AH,Hofman FM,Chen L,Chen TC
11-9985-81 was used in Immunocytochemistry to develop a approach to safely open the blood-brain barrier , based on the intra-arterial (IA) injection of NEO100, a highly purified version of the natural monoterpene perillyl alcohol.
Sat Jan 30 00:00:00 EST 2021
Multifaceted modes of action of the anticancer probiotic Enterococcus hirae.
Cell death and differentiation
Goubet AG,Wheeler R,Fluckiger A,Qu B,Lemaître F,Iribarren K,Mondragón L,Tidjani Alou M,Pizzato E,Durand S,Derosa L,Aprahamian F,Bossut N,Moya-Nilges M,Derrien D,Chen G,Leduc M,Joseph A,Pons N,Le Chatelier E,Segata N,Yonekura S,Iebba V,Kepp O,Raoult D,André F,Kroemer G,Boneca IG,Zitvogel L,Daillère R
11-9985-82 was used in Flow cytometry/Cell sorting to surmise that immunological, metabolic, epithelial, and microbial modes of action of the live E. hirae cooperate to circumvent primary resistance to therapy.
Thu Jul 01 00:00:00 EDT 2021
DNA Methylation Patterns in T Cells of Naïve and Influenza A Virus-Infected Mice Developmentally Exposed to an Aryl Hydrocarbon Receptor Ligand.
Environmental health perspectives
Burke CG,Myers JR,Post CM,Boulé LA,Lawrence BP
11-9985-82 was used in Flow Cytometry to identify cellular mechanisms that drive impaired CD4+ T-cell responses later in life following maternal exposure to an exogenous aryl hydrocarbon receptor. ligand.
Fri Jan 01 00:00:00 EST 2021
Histone deacetylase 3 represses cholesterol efflux during CD4+ T-cell activation.
eLife
Wilfahrt D,Philips RL,Lama J,Kizerwetter M,Shapiro MJ,McCue SA,Kennedy MM,Rajcula MJ,Zeng H,Shapiro VS
Published figure using CD279 (PD-1) monoclonal antibody (Product # 11-9985-82) in Flow Cytometry
Thu Dec 02 00:00:00 EST 2021
Ketogenic diet and ketone bodies enhance the anticancer effects of PD-1 blockade.
JCI insight
Ferrere G,Tidjani Alou M,Liu P,Goubet AG,Fidelle M,Kepp O,Durand S,Iebba V,Fluckiger A,Daillère R,Thelemaque C,Grajeda-Iglesias C,Alves Costa Silva C,Aprahamian F,Lefevre D,Zhao L,Ryffel B,Colomba E,Arnedos M,Drubay D,Rauber C,Raoult D,Asnicar F,Spector T,Segata N,Derosa L,Kroemer G,Zitvogel L
Published figure using CD279 (PD-1) monoclonal antibody (Product # 11-9985-82) in Flow Cytometry
Mon Jan 25 00:00:00 EST 2021
PTENα functions as an immune suppressor and promotes immune resistance in PTEN-mutant cancer.
Nature communications
Sun Y,Lu D,Yin Y,Song J,Liu Y,Hao W,Qi F,Zhang G,Zhang X,Liu L,Lin Z,Liang H,Zhao X,Jin Y,Yin Y
Published figure using CD279 (PD-1) monoclonal antibody (Product # 11-9985-82) in Flow Cytometry
Thu Aug 26 00:00:00 EDT 2021
Stearoyl-CoA Desaturase-Mediated Monounsaturated Fatty Acid Availability Supports Humoral Immunity.
Cell reports
Zhou X,Zhu X,Li C,Li Y,Ye Z,Shapiro VS,Copland JA,Hitosugi T,Bernlohr DA,Sun J,Zeng H
Published figure using CD279 (PD-1) monoclonal antibody (Product # 11-9985-82) in Flow Cytometry
Tue Jan 05 00:00:00 EST 2021
Graded RhoA GTPase Expression in Treg Cells Distinguishes Tumor Immunity From Autoimmunity.
Frontiers in immunology
Kalim KW,Yang JQ,Modur V,Nguyen P,Li Y,Zheng Y,Guo F
Published figure using CD279 (PD-1) monoclonal antibody (Product # 11-9985-82) in Flow Cytometry
Tue Jan 11 00:00:00 EST 2022
Assessing Lupus-Like Disease in Murine Model Systems.
Current protocols
Lee HY,Celhar T,Fairhurst AM
11-9985-82 was used in Flow Cytometry to evaluate the underlying immunological features of the disease, as a more sensitive strategy to understand the disease itself and the mechanisms of potential novel therapeutics.
Mon Nov 01 00:00:00 EDT 2021
Activation of regulatory T cells triggers specific changes in glycosylation associated with Siglec-1-dependent inflammatory responses.
Wellcome open research
Wu G,Murugesan G,Nagala M,McCraw A,Haslam SM,Dell A,Crocker PR
11-9985-82 was used in Flow Cytometry to investigate the molecular basis for Siglec-1 binding to regulatory T cells using in vitro-induced cells as a model system.
Tue Mar 01 00:00:00 EST 2022
Activation of regulatory T cells triggers specific changes in glycosylation associated with Siglec-1-dependent inflammatory responses.
Wellcome open research
Wu G,Murugesan G,Nagala M,McCraw A,Haslam SM,Dell A,Crocker PR
11-9985-82 was used in Flow Cytometry to investigate the molecular basis for Siglec-1 binding to regulatory T cells using in vitro-induced cells as a model system.
Tue Mar 01 00:00:00 EST 2022
TBL1XR1 Mutations Drive Extranodal Lymphoma by Inducing a Pro-tumorigenic Memory Fate.
Cell
Venturutti L,Teater M,Zhai A,Chadburn A,Babiker L,Kim D,Béguelin W,Lee TC,Kim Y,Chin CR,Yewdell WT,Raught B,Phillip JM,Jiang Y,Staudt LM,Green MR,Chaudhuri J,Elemento O,Farinha P,Weng AP,Nissen MD,Steidl C,Morin RD,Scott DW,Privé GG,Melnick AM
11-9985-82 was used in Flow Cytometry to show that TBL1XR1 mutations skew the humoral immune response toward generating abnormal immature memory B cells (MB), while impairing plasma cell differentiation.
Thu Jul 23 00:00:00 EDT 2020
TREM2 Modulation Remodels the Tumor Myeloid Landscape Enhancing Anti-PD-1 Immunotherapy.
Cell
Molgora M,Esaulova E,Vermi W,Hou J,Chen Y,Luo J,Brioschi S,Bugatti M,Omodei AS,Ricci B,Fronick C,Panda SK,Takeuchi Y,Gubin MM,Faccio R,Cella M,Gilfillan S,Unanue ER,Artyomov MN,Schreiber RD,Colonna M
11-9985-82 was used in Flow Cytometry to show that Trem2-/- mice are more resistant to growth of various cancers than wild-type mice and are more responsive to anti-PD-1 immunotherapy.
Thu Aug 20 00:00:00 EDT 2020
Mutant EZH2 Induces a Pre-malignant Lymphoma Niche by Reprogramming the Immune Response.
Cancer cell
Béguelin W,Teater M,Meydan C,Hoehn KB,Phillip JM,Soshnev AA,Venturutti L,Rivas MA,Calvo-Fernández MT,Gutierrez J,Camarillo JM,Takata K,Tarte K,Kelleher NL,Steidl C,Mason CE,Elemento O,Allis CD,Kleinstein SH,Melnick AM
11-9985 was used in Flow cytometry/Cell sorting to show that EZH2 mutations initiate FL by attenuating germinal center(GC) B cell requirement for T cell help and driving slow expansion of GC centrocytes that become enmeshed with and dependent on follicular dendritic cells.
Mon May 11 00:00:00 EDT 2020
Serum HBsAg clearance has minimal impact on CD8+ T cell responses in mouse models of HBV infection.
The Journal of experimental medicine
Fumagalli V,Di Lucia P,Venzin V,Bono EB,Jordan R,Frey CR,Delaney W,Chisari FV,Guidotti LG,Iannacone M
Published figure using CD279 (PD-1) monoclonal antibody (Product # 11-9985-82) in Flow Cytometry
Mon Nov 02 00:00:00 EST 2020
B cells are sufficient to prime the dominant CD4+ Tfh response to Plasmodium infection.
The Journal of experimental medicine
Arroyo EN,Pepper M
Published figure using CD279 (PD-1) monoclonal antibody (Product # 11-9985-82) in Flow Cytometry
Mon Feb 03 00:00:00 EST 2020
Inhibition of the Wnt/β-catenin pathway enhances antitumor immunity in ovarian cancer.
Therapeutic advances in medical oncology
Doo DW,Meza-Perez S,Londoño AI,Goldsberry WN,Katre AA,Boone JD,Moore DJ,Hudson CT,Betella I,McCaw TR,Gangrade A,Bao R,Luke JJ,Yang ES,Birrer MJ,Starenki D,Cooper SJ,Buchsbaum DJ,Norian LA,Randall TD,Arend RC
Published figure using CD279 (PD-1) monoclonal antibody (Product # 11-9985-82) in Flow Cytometry
Thu Apr 14 00:00:00 EDT 2022
Recombinant programmed cell death 1 inhibits psoriatic inflammation in imiquimod‑treated mice.
International journal of molecular medicine
Peng S,Cao M,Sun X,Zhou Y,Chen CY,Ma T,Li H,Li B,Zhu B,Li X
11-9985-82 was used in Flow Cytometry to demonstrate that inhibition of PD‚1 function with antibodies promoted psoriasis development.
Sat Aug 01 00:00:00 EDT 2020
Gene silencing of indoleamine 2,3-dioxygenase 1 inhibits lung cancer growth by suppressing T-cell exhaustion.
Oncology letters
Shang K,Wang Z,Hu Y,Huang Y,Yuan K,Yu Y
Published figure using CD279 (PD-1) monoclonal antibody (Product # 11-9985-82) in Flow Cytometry
Mon Jun 01 00:00:00 EDT 2020
Lysosomal Acid Lipase Is Required for Donor T Cells to Induce Graft-versus-Host Disease.
Cell reports
Nguyen HD,Ticer T,Bastian D,Kuril S,Li H,Du H,Yan C,Yu XZ
Published figure using CD279 (PD-1) monoclonal antibody (Product # 11-9985-82) in Flow Cytometry
Tue Oct 27 00:00:00 EDT 2020
5-Azacytidine Potentiates Anti-tumor Immunity in a Model of Pancreatic Ductal Adenocarcinoma.
Frontiers in immunology
Ebelt ND,Zuniga E,Johnson BL,Diamond DJ,Manuel ER
Published figure using CD279 (PD-1) monoclonal antibody (Product # 11-9985-82) in Flow Cytometry
Fri Mar 26 00:00:00 EDT 2021
The Selenoprotein MsrB1 Instructs Dendritic Cells to Induce T-Helper 1 Immune Responses.
Antioxidants (Basel, Switzerland)
Lee HJ,Park JS,Yoo HJ,Lee HM,Lee BC,Kim JH
Published figure using CD279 (PD-1) monoclonal antibody (Product # 11-9985-82) in Flow Cytometry
Tue Oct 20 00:00:00 EDT 2020
MRI of tumor T cell infiltration in response to checkpoint inhibitor therapy.
Journal for immunotherapy of cancer
Jiang X,Dudzinski S,Beckermann KE,Young K,McKinley E,J McIntyre O,Rathmell JC,Xu J,Gore JC
11-9985-82 was used in Flow Cytometry to propose an innovative concept that a sufficiently large influx of tumor infiltrating T cells, which have a smaller diameter than cancer cells, will change the diameter distribution and decrease the average size of cells within a volume to a degree that can be quantified by non-invasive MRI.
Mon Jun 01 00:00:00 EDT 2020
Endogenous retroviral proteins provide an immunodominant but not requisite antigen in a murine immunotherapy tumor model.
Oncoimmunology
Ye X,Waite JC,Dhanik A,Gupta N,Zhong M,Adler C,Malahias E,Ni M,Wei Y,Gurer C,Zhang W,Macdonald LE,Murphy AJ,Sleeman MA,Skokos D
Published figure using CD279 (PD-1) monoclonal antibody (Product # 11-9985-82) in Flow Cytometry
Wed May 13 00:00:00 EDT 2020
Defining Genetic Variation in Widely Used Congenic and Backcrossed Mouse Models Reveals Varied Regulation of Genes Important for Immune Responses.
Immunity
Chisolm DA,Cheng W,Colburn SA,Silva-Sanchez A,Meza-Perez S,Randall TD,Weinmann AS
11-9985 was used in Flow cytometry/Cell sorting to present strategies to analyze next-generation sequencing datasets to define genetic variation in B6 congenic and transgenic strains.
Tue Jul 16 00:00:00 EDT 2019
Combination PD-1 and PD-L1 Blockade Promotes Durable Neoantigen-Specific T Cell-Mediated Immunity in Pancreatic Ductal Adenocarcinoma.
Cell reports
Burrack AL,Spartz EJ,Raynor JF,Wang I,Olson M,Stromnes IM
Published figure using CD279 (PD-1) monoclonal antibody (Product # 11-9985-82) in Flow Cytometry
Tue Aug 20 00:00:00 EDT 2019
CD160 serves as a negative regulator of NKT cells in acute hepatic injury.
Nature communications
Kim TJ,Park G,Kim J,Lim SA,Kim J,Im K,Shin MH,Fu YX,Del Rio ML,Rodriguez-Barbosa JI,Yee C,Suh KS,Kim SJ,Ha SJ,Lee KM
11-9985-82 was used in Flow cytometry/Cell sorting to show that CD160 is not essential for NKT cell development.
Mon Jul 22 00:00:00 EDT 2019
CXCR3 chemokine receptor guides Trypanosoma cruzi-specific T-cells triggered by DNA/adenovirus ASP2 vaccine to heart tissue after challenge.
PLoS neglected tropical diseases
Pontes Ferreira C,Cariste LM,Ferri Moraschi B,Ferrarini Zanetti B,Won Han S,Araki Ribeiro D,Vieira Machado A,Lannes-Vieira J,Gazzinelli RT,Vasconcelos JRC
11-9985 was used in Flow cytometry/Cell sorting to study how CXCR3 and its ligands drive Trypanosoma cruzi-specific effector CD8+ T-cells into infected heart tissue.
Mon Jul 01 00:00:00 EDT 2019
Pulsatile MEK Inhibition Improves Anti-tumor Immunity and T Cell Function in Murine Kras Mutant Lung Cancer.
Cell reports
Choi H,Deng J,Li S,Silk T,Dong L,Brea EJ,Houghton S,Redmond D,Zhong H,Boiarsky J,Akbay EA,Smith PD,Merghoub T,Wong KK,Wolchok JD
11-9985 was used in Flow cytometry/Cell sorting to set the foundation and show the importance of a combinatorial therapeutic strategy using pulsatile targeted therapy together with immunotherapy to optimally enhance tumor delay and promote long-term anti-tumor immunity.
Tue Apr 16 00:00:00 EDT 2019
Initiation of Antiviral B Cell Immunity Relies on Innate Signals from Spatially Positioned NKT Cells.
Cell
Gaya M,Barral P,Burbage M,Aggarwal S,Montaner B,Warren Navia A,Aid M,Tsui C,Maldonado P,Nair U,Ghneim K,Fallon PG,Sekaly RP,Barouch DH,Shalek AK,Bruckbauer A,Strid J,Batista FD
Published figure using CD279 (PD-1) monoclonal antibody (Product # 11-9985-82) in Flow Cytometry
Thu Jan 25 00:00:00 EST 2018
Co-inhibitory Molecule B7 Superfamily Member 1 Expressed by Tumor-Infiltrating Myeloid Cells Induces Dysfunction of Anti-tumor CD8+ T Cells.
Immunity
Li J,Lee Y,Li Y,Jiang Y,Lu H,Zang W,Zhao X,Liu L,Chen Y,Tan H,Yang Z,Zhang MQ,Mak TW,Ni L,Dong C
11-9985 was used in Flow cytometry/Cell sorting to demonstrate that increased B7S1 expression in myeloid cells from human hepatocellular carcinoma is correlated with CD8+ T cell dysfunction.
Tue Apr 17 00:00:00 EDT 2018
Dysfunction of Natural Killer Cells by FBP1-Induced Inhibition of Glycolysis during Lung Cancer Progression.
Cell metabolism
Cong J,Wang X,Zheng X,Wang D,Fu B,Sun R,Tian Z,Wei H
11-9985 was used in Flow cytometry/Cell sorting to identify novel mechanisms in natural killer cell dysfunction.
Tue Aug 07 00:00:00 EDT 2018
PD-1 Blockade Overcomes Adaptive Immune Resistance in Treatment with Anchored-GM-CSF Bladder Cancer Cells Vaccine.
Journal of Cancer
Zhang X,Shi X,Li J,Mo L,Hu Z,Gao J,Wu S,Long Z
Published figure using CD279 (PD-1) monoclonal antibody (Product # 11-9985-82) in Immunohistochemistry
Thu Oct 01 00:00:00 EDT 2020
PD-1 Blockade Overcomes Adaptive Immune Resistance in Treatment with Anchored-GM-CSF Bladder Cancer Cells Vaccine.
Journal of Cancer
Zhang X,Shi X,Li J,Mo L,Hu Z,Gao J,Wu S,Long Z
Published figure using CD279 (PD-1) monoclonal antibody (Product # 11-9985-82) in Immunohistochemistry
Thu Oct 01 00:00:00 EDT 2020
PD-1 Blockade Overcomes Adaptive Immune Resistance in Treatment with Anchored-GM-CSF Bladder Cancer Cells Vaccine.
Journal of Cancer
Zhang X,Shi X,Li J,Mo L,Hu Z,Gao J,Wu S,Long Z
Published figure using CD279 (PD-1) monoclonal antibody (Product # 11-9985-82) in Immunohistochemistry
Thu Oct 01 00:00:00 EDT 2020
Clinical significance of CCR7+CD8+ T cells in kidney transplant recipients with allograft rejection.
Scientific reports
Kim KW,Kim BM,Doh KC,Cho ML,Yang CW,Chung BH
11-9985 was used in Flow cytometry/Cell sorting to reveal the impact of CCR7+CD8+ T cells has on the proliferation and differentiation of T cells into effector cells in kidney transplant patients.
Mon Jun 11 00:00:00 EDT 2018
Cholesterol Accumulation in Dendritic Cells Links the Inflammasome to Acquired Immunity.
Cell metabolism
Westerterp M,Gautier EL,Ganda A,Molusky MM,Wang W,Fotakis P,Wang N,Randolph GJ,D'Agati VD,Yvan-Charvet L,Tall AR
11-9985 was used in Flow cytometry/Cell sorting to identify an essential role of DC cholesterol efflux pathways in maintaining immune tolerance.
Tue Jun 06 00:00:00 EDT 2017
Oncolytic Adenovirus and Tumor-Targeting Immune Modulatory Therapy Improve Autologous Cancer Vaccination.
Cancer research
Jiang H,Rivera-Molina Y,Gomez-Manzano C,Clise-Dwyer K,Bover L,Vence LM,Yuan Y,Lang FF,Toniatti C,Hossain MB,Fueyo J
Published figure using CD279 (PD-1) monoclonal antibody (Product # 11-9985-82) in Flow Cytometry
Sat Jul 15 00:00:00 EDT 2017
LFA-1 Mediates Cytotoxicity and Tissue Migration of Specific CD8+ T Cells after Heterologous Prime-Boost Vaccination against Trypanosoma cruzi Infection.
Frontiers in immunology
Ferreira CP,Cariste LM,Santos Virgílio FD,Moraschi BF,Monteiro CB,Vieira Machado AM,Gazzinelli RT,Bruna-Romero O,Menin Ruiz PL,Ribeiro DA,Lannes-Vieira J,Lopes MF,Rodrigues MM,de Vasconcelos JRC
11-9985 was used in Flow cytometry/Cell sorting to explore the roles of LFA-1 and VLA-4 in the migration of specific CD8+ T cells generated by heterologous prime-boost immunisation during experimental infection with Trypanosoma cruzi.
Wed Nov 20 00:00:00 EST 2019
Cblb-deficient T cells are less susceptible to PD-L1-mediated inhibition.
Oncotarget
Peer S,Baier G,Gruber T
Published figure using CD279 (PD-1) monoclonal antibody (Product # 11-9985-82) in Flow Cytometry
Tue Jun 27 00:00:00 EDT 2017
Therapeutic efficacy of combined vaccination against tumor pericyte-associated antigens DLK1 and DLK2 in mice.
Oncoimmunology
Fabian KP,Chi-Sabins N,Taylor JL,Fecek R,Weinstein A,Storkus WJ
11-9985-82 was used in Flow cytometry/Cell sorting to show that therapeutic vaccination against DLK1 results in slowed tumour growth, and compensatory expression of DLK2 by tumour-associated pericytes.
Tue Jan 12 00:00:00 EST 2021
Therapeutic efficacy of combined vaccination against tumor pericyte-associated antigens DLK1 and DLK2 in mice.
Oncoimmunology
Fabian KP,Chi-Sabins N,Taylor JL,Fecek R,Weinstein A,Storkus WJ
11-9985-82 was used in Flow cytometry/Cell sorting to show that therapeutic vaccination against DLK1 results in slowed tumour growth, and compensatory expression of DLK2 by tumour-associated pericytes.
Tue Jan 12 00:00:00 EST 2021
Intratumoral modulation of the inducible co-stimulator ICOS by recombinant oncolytic virus promotes systemic anti-tumour immunity.
Nature communications
Zamarin D,Holmgaard RB,Ricca J,Plitt T,Palese P,Sharma P,Merghoub T,Wolchok JD,Allison JP
Published figure using CD279 (PD-1) monoclonal antibody (Product # 11-9985-82) in Flow Cytometry
Mon Feb 13 00:00:00 EST 2017
EZH2 enables germinal centre formation through epigenetic silencing of CDKN1A and an Rb-E2F1 feedback loop.
Nature communications
Béguelin W,Rivas MA,Calvo Fernández MT,Teater M,Purwada A,Redmond D,Shen H,Challman MF,Elemento O,Singh A,Melnick AM
11-9985 was used in Flow cytometry/Cell sorting to show EZH2 mediates germinal centre formation through epigenetic silencing of CDKN1A and release of cell cycle checkpoints.
Thu Oct 12 00:00:00 EDT 2017
A Human Trypanosome Suppresses CD8+ T Cell Priming by Dendritic Cells through the Induction of Immune Regulatory CD4+ Foxp3+ T Cells.
PLoS pathogens
Ersching J,Basso AS,Kalich VL,Bortoluci KR,Rodrigues MM
11-9985 was used in Flow cytometry/Cell sorting to demonstrate a newly described mechanism of CD8+ T cell priming by CD4+ Foxp3+ T cells during Trypanosoma cruzi infection.
Wed Jun 01 00:00:00 EDT 2016
Lack of the programmed death-1 receptor renders host susceptible to enteric microbial infection through impairing the production of the mucosal natural killer cell effector molecules.
Journal of leukocyte biology
Solaymani-Mohammadi S,Lakhdari O,Minev I,Shenouda S,Frey BF,Billeskov R,Singer SM,Berzofsky JA,Eckmann L,Kagnoff MF
11-9985 was used in Flow cytometry/Cell sorting to identify the role of the programmed death-1 receptor in early host microbial defence at the intestinal mucosa.
Tue Mar 01 00:00:00 EST 2016
Contamination of DNase Preparations Confounds Analysis of the Role of DNA in Alum-Adjuvanted Vaccines.
Journal of immunology (Baltimore, Md. : 1950)
Noges LE,White J,Cambier JC,Kappler JW,Marrack P
11-9985 was used in Flow cytometry/Cell sorting to investigate the contribution of host DNA released at the site of vaccine injection to the adjuvant activity of alum.
Mon Aug 15 00:00:00 EDT 2016
Growth and metastasis of lung adenocarcinoma is potentiated by BMP4-mediated immunosuppression.
Oncoimmunology
Chen L,Yi X,Goswami S,Ahn YH,Roybal JD,Yang Y,Diao L,Peng D,Peng D,Fradette JJ,Wang J,Byers LA,Kurie JM,Ullrich SE,Qin FX,Gibbons DL
Tue Jan 12 00:00:00 EST 2021
The stress kinase GCN2 does not mediate suppression of antitumor T cell responses by tryptophan catabolism in experimental melanomas.
Oncoimmunology
Sonner JK,Deumelandt K,Ott M,Thomé CM,Rauschenbach KJ,Schulz S,Munteanu B,Mohapatra S,Adam I,Hofer AC,Feuerer M,Opitz CA,Hopf C,Wick W,Platten M
Published figure using CD279 (PD-1) monoclonal antibody (Product # 11-9985-82) in Flow Cytometry
Tue Jan 12 00:00:00 EST 2021
Alternative splicing of MALT1 controls signalling and activation of CD4(+) T cells.
Nature communications
Meininger I,Griesbach RA,Hu D,Gehring T,Seeholzer T,Bertossi A,Kranich J,Oeckinghaus A,Eitelhuber AC,Greczmiel U,Gewies A,Schmidt-Supprian M,Ruland J,Brocker T,Heissmeyer V,Heyd F,Krappmann D
11-9985 was used in Flow cytometry/Cell sorting to study how TCR-induced alternative splicing augments MALT1 scaffolding to enhance downstream signalling and to promote optimal T-cell activation.
Tue Apr 12 00:00:00 EDT 2016
Cholesterol-Independent Suppression of Lymphocyte Activation, Autoimmunity, and Glomerulonephritis by Apolipoprotein A-I in Normocholesterolemic Lupus-Prone Mice.
Journal of immunology (Baltimore, Md. : 1950)
Black LL,Srivastava R,Schoeb TR,Moore RD,Barnes S,Kabarowski JH
11-9985 was used in Flow cytometry/Cell sorting to investigate the immunosuppressive and antiinflammatory properties of ApoA-I in a normocholesterolemic bone marrow transfer model of systemic lupus erythematosus.
Sun Nov 15 00:00:00 EST 2015
Regulation of autoimmune germinal center reactions in lupus-prone BXD2 mice by follicular helper T cells.
PloS one
Kim YU,Lim H,Jung HE,Wetsel RA,Chung Y
11-9985 was used in Flow cytometry/Cell sorting to demonstrate that Tfh cells rather than Th17 cells contribute to the autoimmune germinal center reactions in BXD2 mice.
Fri Jan 29 00:00:00 EST 2016
Predicting immunogenic tumour mutations by combining mass spectrometry and exome sequencing.
Nature
Yadav M,Jhunjhunwala S,Phung QT,Lupardus P,Tanguay J,Bumbaca S,Franci C,Cheung TK,Fritsche J,Weinschenk T,Modrusan Z,Mellman I,Lill JR,Delamarre L
11-9985 was used in Flow cytometry/Cell sorting to indicate that a suitable prediction algorithm may provide an approach for the pharmacodynamic monitoring of T-cell responses and provide personalised vaccines.
Thu Nov 27 00:00:00 EST 2014
Enhancing virus-specific immunity in vivo by combining therapeutic vaccination and PD-L1 blockade in chronic hepadnaviral infection.
PLoS pathogens
Liu J,Zhang E,Ma Z,Wu W,Kosinska A,Zhang X,Möller I,Seiz P,Glebe D,Wang B,Yang D,Lu M,Roggendorf M
11-9985 was used in Flow cytometry/Cell sorting to examine whether in vivo blockade of the PD-1 pathway enhances virus-specific T cell immunity and leads to the resolution of chronic hepadnaviral infection in the woodchuck model.
Wed Jan 01 00:00:00 EST 2014
T/B-cell interactions are more transient in response to weak stimuli in SLE-prone mice.
European journal of immunology
Sinai P,Dozmorov IM,Song R,Schwartzberg PL,Wakeland EK,Wülfing C
11-9985 was used in in vitro experiments to analyse primary T and B cells from a mouse model of systemic lupus erythematosus prior to the onset of disease.
Mon Dec 01 00:00:00 EST 2014
Metastasis is regulated via microRNA-200/ZEB1 axis control of tumour cell PD-L1 expression and intratumoral immunosuppression.
Nature communications
Chen L,Gibbons DL,Goswami S,Cortez MA,Ahn YH,Byers LA,Zhang X,Yi X,Dwyer D,Lin W,Diao L,Wang J,Roybal J,Patel M,Ungewiss C,Peng D,Antonia S,Mediavilla-Varela M,Robertson G,Suraokar M,Welsh JW,Erez B,Wistuba II,Chen L,Peng D,Wang S,Ullrich SE,Heymach JV,Kurie JM,Qin FX
Published figure using CD279 (PD-1) monoclonal antibody (Product # 11-9985-82) in Flow Cytometry
Tue Oct 28 00:00:00 EDT 2014
PD-L1 expression by neurons nearby tumors indicates better prognosis in glioblastoma patients.
The Journal of neuroscience : the official journal of the Society for Neuroscience
Liu Y,Carlsson R,Ambjørn M,Hasan M,Badn W,Darabi A,Siesjö P,Issazadeh-Navikas S
11-9985 was used in Flow cytometry/Cell sorting to study the relationship between program death-ligand expression and clinical outcome in glioblastoma multiforme patients.
Wed Aug 28 00:00:00 EDT 2013
Neonatal follicular Th cell responses are impaired and modulated by IL-4.
Journal of immunology (Baltimore, Md. : 1950)
Debock I,Jaworski K,Chadlaoui H,Delbauve S,Passon N,Twyffels L,Leo O,Flamand V
11-9985 was used in Flow cytometry/Cell sorting to suggest that defective humoral immunity in early life is associated with limited and IL-4-modulated follicular Th cell responses.
Thu Aug 01 00:00:00 EDT 2013
PD-1 regulates T cell proliferation in a tissue and subset-specific manner during normal mouse pregnancy.
Immunological investigations
Shepard MT,Bonney EA
11-9985 was used in Functional assays to suggest that there is a state of dynamic T cell homeostasis during pregnancy which is partially supported by PD-1 signalling.
Tue Feb 11 00:00:00 EST 2014
Transfer of HBV genomes using low doses of adenovirus vectors leads to persistent infection in immune competent mice.
Gastroenterology
Huang LR,Gäbel YA,Graf S,Arzberger S,Kurts C,Heikenwalder M,Knolle PA,Protzer U
11-9985 was used in Flow cytometry/Cell sorting to demonstrate that infection of immunocompetent mice with low doses of adenovirus vectors results in persistent HBV infection.
Fri Jun 01 00:00:00 EDT 2012
Intranasal but not intravenous delivery of the adjuvant α-galactosylceramide permits repeated stimulation of natural killer T cells in the lung.
European journal of immunology
Courtney AN,Thapa P,Singh S,Wishahy AM,Zhou D,Sastry J
11-9985 was used in Flow cytometry/Cell sorting to show that a mucosal, instead of intravenous, route of delivery for α-galactosylceramide enables repeated activation of NKT cells and DCs.
Tue Nov 01 00:00:00 EDT 2011
TCR-dependent and -independent activation underlie liver-specific regulation of NKT cells.
Journal of immunology (Baltimore, Md. : 1950)
Subleski JJ,Hall VL,Wolfe TB,Scarzello AJ,Weiss JM,Chan T,Hodge DL,Back TC,Ortaldo JR,Wiltrout RH
11-9985 was used in Flow cytometry/Cell sorting to investigate TCR -dependent and -independent activation of NKT cells in the liver.
Sat Jan 15 00:00:00 EST 2011
Farnesyltransferase inhibitor FTI-277 reduces mortality of septic mice along with improved bacterial clearance.
The Journal of pharmacology and experimental therapeutics
Yang W,Yamada M,Tamura Y,Chang K,Mao J,Zou L,Feng Y,Kida K,Scherrer-Crosbie M,Chao W,Ichinose F,Yu YM,Fischman AJ,Tompkins RG,Yao S,Kaneki M
Published figure using CD279 (PD-1) monoclonal antibody (Product # 11-9985-82) in Flow Cytometry
Thu Dec 01 00:00:00 EST 2011
Partial restoration of T-cell function in aged mice by in vitro blockade of the PD-1/ PD-L1 pathway.
Aging cell
Lages CS,Lewkowich I,Sproles A,Wills-Karp M,Chougnet C
11-9985 was used in Flow cytometry/Cell sorting to suggest that blockade of the PD-1/PD-L1 is not likely to be efficient at restoring exhausted T-cell responses in aged hosts.
Fri Oct 01 00:00:00 EDT 2010
Naturally occurring and inducible T-regulatory cells modulating immune response in allergic asthma.
American journal of respiratory and critical care medicine
McGee HS,Agrawal DK
11-9985 was used in Flow cytometry/Cell sorting to suggest that PD-1 by Tregs may be a target for treating asthma by reversing airway hyperresponsiveness.
Sat Aug 01 00:00:00 EDT 2009
Blockade of PD-1/B7-H1 interaction restores effector CD8+ T cell responses in a hepatitis C virus core murine model.
Journal of immunology (Baltimore, Md. : 1950)
Lukens JR,Cruise MW,Lassen MG,Hahn YS
11-9985 was used in Flow cytometry/Cell sorting to determine the mechanism of the hepatitis C virus core in suppressing Ag-specific CD8(+) T cell responses.
Tue Apr 01 00:00:00 EDT 2008
Interaction between B7-H1 and PD-1 determines initiation and reversal of T-cell anergy.
Blood
Tsushima F,Yao S,Shin T,Flies A,Flies S,Xu H,Tamada K,Pardoll DM,Chen L
11-9985 was used in Flow cytometry/Cell sorting to reveal previously unappreciated roles of B7-H1 and PD-1 interaction in the control of initiation and reversion of T-cell anergy.
Sun Jul 01 00:00:00 EDT 2007
The programmed death-1 (PD-1) pathway regulates autoimmune diabetes in nonobese diabetic (NOD) mice.
The Journal of experimental medicine
Ansari MJ,Salama AD,Chitnis T,Smith RN,Yagita H,Akiba H,Yamazaki T,Azuma M,Iwai H,Khoury SJ,Auchincloss H,Sayegh MH
Mon Jul 07 00:00:00 EDT 2003
The programmed death-1 (PD-1) pathway regulates autoimmune diabetes in nonobese diabetic (NOD) mice.
The Journal of experimental medicine
Ansari MJ,Salama AD,Chitnis T,Smith RN,Yagita H,Akiba H,Yamazaki T,Azuma M,Iwai H,Khoury SJ,Auchincloss H,Sayegh MH
Mon Jul 07 00:00:00 EDT 2003
The programmed death-1 (PD-1) pathway regulates autoimmune diabetes in nonobese diabetic (NOD) mice.
The Journal of experimental medicine
Ansari MJ,Salama AD,Chitnis T,Smith RN,Yagita H,Akiba H,Yamazaki T,Azuma M,Iwai H,Khoury SJ,Auchincloss H,Sayegh MH
Mon Jul 07 00:00:00 EDT 2003
