Product References
Fasudil-modified macrophages reduce inflammation and regulate the immune response in experimental autoimmune encephalomyelitis.
Neural regeneration research
Liu C,Guo S,Liu R,Guo M,Wang Q,Chai Z,Xiao B,Ma C
Published figure using CD40 monoclonal antibody (Product # 14-0401-82) in Flow Cytometry
Fri Mar 01 00:00:00 EST 2024
Prostaglandin E2 serves a dual role in regulating the migration of dendritic cells.
International journal of molecular medicine
Diao G,Huang J,Zheng X,Sun X,Tian M,Han J,Guo J
Published figure using CD40 monoclonal antibody (Product # 14-0401-82) in Flow Cytometry
Fri Jan 01 00:00:00 EST 2021
Myeloid and plasmacytoid dendritic cell combined vaccines loaded with heat-treated tumor cell lysates enhance antitumor activity in murine lung cancer.
Oncology letters
Chen H,Tan J,Li X,Li H,Wu W,Wu Y,Zhang J,Gu L
Published figure using CD40 monoclonal antibody (Product # 14-0401-82) in Flow Cytometry
Mon Feb 01 00:00:00 EST 2021
Neuroimmune Consequences of eIF4E Phosphorylation on Chemotherapy-Induced Peripheral Neuropathy.
Frontiers in immunology
Agalave NM,Mody PH,Szabo-Pardi TA,Jeong HS,Burton MD
Published figure using CD40 monoclonal antibody (Product # 14-0401-82) in Flow Cytometry
Mon Sep 20 00:00:00 EDT 2021
Modulation of lactate-lysosome axis in dendritic cells by clotrimazole potentiates antitumor immunity.
Journal for immunotherapy of cancer
Wang Z,Xu F,Hu J,Zhang H,Cui L,Lu W,He W,Wang X,Li M,Zhang H,Xiong W,Xie C,Liu Y,Zhou P,Liu J,Huang P,Qin XF,Xia X
Published figure using CD40 monoclonal antibody (Product # 14-0401-82) in Flow Cytometry
Sat May 01 00:00:00 EDT 2021
E6‑regulated overproduction of prostaglandin E2 may inhibit migration of dendritic cells in human papillomavirus 16‑positive cervical lesions.
International journal of oncology
Huang J,Diao G,Zhang Q,Chen Y,Han J,Guo J
Published figure using CD40 monoclonal antibody (Product # 14-0401-82) in Flow Cytometry
Wed Apr 01 00:00:00 EDT 2020
Senolytics prevent mt-DNA-induced inflammation and promote the survival of aged organs following transplantation.
Nature communications
Iske J,Seyda M,Heinbokel T,Maenosono R,Minami K,Nian Y,Quante M,Falk CS,Azuma H,Martin F,Passos JF,Niemann CU,Tchkonia T,Kirkland JL,Elkhal A,Tullius SG
Published figure using CD40 monoclonal antibody (Product # 14-0401-82) in Flow Cytometry
Thu Aug 27 00:00:00 EDT 2020
Tregitopes regulate the tolerogenic immune response and decrease the foetal death rate in abortion-prone mouse matings.
Scientific reports
Kedzierska AE,Lorek D,Slawek A,Chelmonska-Soyta A
Published figure using CD40 monoclonal antibody (Product # 14-0401-82) in Flow Cytometry
Mon Jun 29 00:00:00 EDT 2020
Polyanhydride Nanoparticles Induce Low Inflammatory Dendritic Cell Activation Resulting in CD8+ T Cell Memory and Delayed Tumor Progression.
International journal of nanomedicine
Darling R,Senapati S,Christiansen J,Liu L,Ramer-Tait AE,Narasimhan B,Wannemuehler M
Published figure using CD40 monoclonal antibody (Product # 14-0401-82) in Flow Cytometry
Mon Dec 07 00:00:00 EST 2020
cGAS/STING axis mediates a topoisomerase II inhibitor-induced tumor immunogenicity.
The Journal of clinical investigation
Wang Z,Chen J,Hu J,Zhang H,Xu F,He W,Wang X,Li M,Lu W,Zeng G,Zhou P,Huang P,Chen S,Li W,Xia LP,Xia X
Published figure using CD40 monoclonal antibody (Product # 14-0401-82) in Flow Cytometry
Tue Aug 13 00:00:00 EDT 2019
Efficient oral vaccination by bioengineering virus-like particles with protozoan surface proteins.
Nature communications
Serradell MC,Rupil LL,Martino RA,Prucca CG,Carranza PG,Saura A,Fernández EA,Gargantini PR,Tenaglia AH,Petiti JP,Tonelli RR,Reinoso-Vizcaino N,Echenique J,Berod L,Piaggio E,Bellier B,Sparwasser T,Klatzmann D,Luján HD
Published figure using CD40 monoclonal antibody (Product # 14-0401-82) in Flow Cytometry
Mon Jan 21 00:00:00 EST 2019
Bryostatin-1 alleviates experimental multiple sclerosis.
Proceedings of the National Academy of Sciences of the United States of America
Kornberg MD,Smith MD,Shirazi HA,Calabresi PA,Snyder SH,Kim PM
Published figure using CD40 monoclonal antibody (Product # 14-0401-82) in Flow Cytometry
Tue Feb 27 00:00:00 EST 2018
Semaphorin-3E Produced by Immature Dendritic Cells Regulates Activated Natural Killer Cells Migration.
Frontiers in immunology
Alamri A,Rahman R,Zhang M,Alamri A,Gounni AS,Kung SKP
14-0401 was used in Flow cytometry/Cell sorting to reveal a novel role of Sema-3E in limiting NK-cell migrations toward iDC in NK-DC crosstalk.
Thu Jul 11 00:00:00 EDT 2019
FcεRI γ-Chain Negatively Modulates Dectin-1 Responses in Dendritic Cells.
Frontiers in immunology
Pan YG,Yu YL,Lin CC,Lanier LL,Chu CL
Published figure using CD40 monoclonal antibody (Product # 14-0401-82) in Flow Cytometry
Wed Nov 20 00:00:00 EST 2019
Discrimination of the heterogeneity of bone marrow‑derived dendritic cells.
Molecular medicine reports
Wang J,Dai X,Hsu C,Ming C,He Y,Zhang J,Wei L,Zhou P,Wang CY,Yang J,Gong N
Published figure using CD40 monoclonal antibody (Product # 14-0401-82) in Flow Cytometry
Wed Nov 01 00:00:00 EDT 2017
Batf3-dependent CD8α+ Dendritic Cells Aggravates Atherosclerosis via Th1 Cell Induction and Enhanced CCL5 Expression in Plaque Macrophages.
EBioMedicine
Li Y,Liu X,Duan W,Tian H,Zhu G,He H,Yao S,Yi S,Song W,Tang H
Published figure using CD40 monoclonal antibody (Product # 14-0401-82) in Flow Cytometry
Sat Apr 01 00:00:00 EDT 2017
Paeoniflorin Ameliorates Experimental Autoimmune Encephalomyelitis via Inhibition of Dendritic Cell Function and Th17 Cell Differentiation.
Scientific reports
Zhang H,Qi Y,Yuan Y,Cai L,Xu H,Zhang L,Su B,Nie H
Published figure using CD40 monoclonal antibody (Product # 14-0401-82) in Flow Cytometry
Mon Feb 06 00:00:00 EST 2017
Tumor-derived exosomes educate dendritic cells to promote tumor metastasis via HSP72/HSP105-TLR2/TLR4 pathway.
Oncoimmunology
Shen Y,Guo D,Weng L,Wang S,Ma Z,Yang Y,Wang P,Wang J,Cai Z
Published figure using CD40 monoclonal antibody (Product # 14-0401-82) in Flow Cytometry
Tue Jan 12 00:00:00 EST 2021
Combination immunotherapy with TLR agonists and checkpoint inhibitors suppresses head and neck cancer.
JCI insight
Sato-Kaneko F,Yao S,Ahmadi A,Zhang SS,Hosoya T,Kaneda MM,Varner JA,Pu M,Messer KS,Guiducci C,Coffman RL,Kitaura K,Matsutani T,Suzuki R,Carson DA,Hayashi T,Cohen EE
Published figure using CD40 monoclonal antibody (Product # 14-0401-82) in Flow Cytometry
Thu Sep 21 00:00:00 EDT 2017
A septin requirement differentiates autonomous and contact-facilitated T cell proliferation.
Nature immunology
Mujal AM,Gilden JK,Gérard A,Kinoshita M,Krummel MF
14-0401 was used in Functional assays to characterise T cells lacking the septin cytoskeleton.
Tue Mar 01 00:00:00 EST 2016
Deficiency of base excision repair enzyme NEIL3 drives increased predisposition to autoimmunity.
The Journal of clinical investigation
Massaad MJ,Zhou J,Tsuchimoto D,Chou J,Jabara H,Janssen E,Glauzy S,Olson BG,Morbach H,Ohsumi TK,Schmitz K,Kyriacos M,Kane J,Torisu K,Nakabeppu Y,Notarangelo LD,Chouery E,Megarbane A,Kang PB,Al-Idrissi E,Aldhekri H,Meffre E,Mizui M,Tsokos GC,Manis JP,Al-Herz W,Wallace SS,Geha RS
14-0401 was used in Functional assays to investigate alterations in immune cell apoptosis during autoimmunity, showing that deficiency in NEIL3 drives increased predisposition to autoimmunity.
Tue Nov 01 00:00:00 EDT 2016
Deficiency of base excision repair enzyme NEIL3 drives increased predisposition to autoimmunity.
The Journal of clinical investigation
Massaad MJ,Zhou J,Tsuchimoto D,Chou J,Jabara H,Janssen E,Glauzy S,Olson BG,Morbach H,Ohsumi TK,Schmitz K,Kyriacos M,Kane J,Torisu K,Nakabeppu Y,Notarangelo LD,Chouery E,Megarbane A,Kang PB,Al-Idrissi E,Aldhekri H,Meffre E,Mizui M,Tsokos GC,Manis JP,Al-Herz W,Wallace SS,Geha RS
14-0401 was used in Functional assays to investigate alterations in immune cell apoptosis during autoimmunity, showing that deficiency in NEIL3 drives increased predisposition to autoimmunity.
Tue Nov 01 00:00:00 EDT 2016
Platelets Guide Leukocytes to Their Sites of Extravasation.
PLoS biology
Zuchtriegel G,Uhl B,Puhr-Westerheide D,Pörnbacher M,Lauber K,Krombach F,Reichel CA
14-0401 was used in Flow cytometry/Cell sorting to uncover a platelet-directed, spatiotemporally organised, multicellular crosstalk that is essential for effective trafficking of leukocytes to the site of inflammation.
Sun May 01 00:00:00 EDT 2016
Nuclear receptor expression atlas in BMDCs: Nr4a2 restricts immunogenicity of BMDCs and impedes EAE.
European journal of immunology
Saini A,Mahajan S,Gupta P
Published figure using CD40 monoclonal antibody (Product # 14-0401-82) in Flow Cytometry
Mon Aug 01 00:00:00 EDT 2016
Repulsive guidance molecule a blockade exerts the immunoregulatory function in DCs stimulated with ABP and LPS.
Human vaccines & immunotherapeutics
Xu X,Gao Y,Zhai Z,Zhang S,Shan F,Feng J
Published figure using CD40 monoclonal antibody (Product # 14-0401-82) in Flow Cytometry
Tue Aug 02 00:00:00 EDT 2016
MyD88/CD40 Genetic Adjuvant Function in Cutaneous Atypical Antigen-Presenting Cells Contributes to DNA Vaccine Immunogenicity.
PloS one
Collinson-Pautz MR,Slawin KM,Levitt JM,Spencer DM
Published figure using CD40 monoclonal antibody (Product # 14-0401-82) in Flow Cytometry
Wed May 31 00:00:00 EDT 2017
D-Alanylation of Teichoic Acids and Loss of Poly-N-Acetyl Glucosamine in Staphylococcus aureus during Exponential Growth Phase Enhance IL-12 Production in Murine Dendritic Cells.
PloS one
Lund LD,Ingmer H,Frøkiær H
Published figure using CD40 monoclonal antibody (Product # 14-0401-82) in Flow Cytometry
Thu Jul 14 00:00:00 EDT 2016
Plasmacytoid dendritic cells orchestrate TLR7-mediated innate and adaptive immunity for the initiation of autoimmune inflammation.
Scientific reports
Takagi H,Arimura K,Uto T,Fukaya T,Nakamura T,Choijookhuu N,Hishikawa Y,Sato K
14-0401 was used in Functional assays to investigate the role of plasmacytoid dendritic cells in autoimmunity, showing that they orchestrate TLR7-mediated immune response and initiate autoimmune inflammation.
Thu Apr 14 00:00:00 EDT 2016
Blood coagulation factor XII drives adaptive immunity during neuroinflammation via CD87-mediated modulation of dendritic cells.
Nature communications
Göbel K,Pankratz S,Asaridou CM,Herrmann AM,Bittner S,Merker M,Ruck T,Glumm S,Langhauser F,Kraft P,Krug TF,Breuer J,Herold M,Gross CC,Beckmann D,Korb-Pap A,Schuhmann MK,Kuerten S,Mitroulis I,Ruppert C,Nolte MW,Panousis C,Klotz L,Kehrel B,Korn T,Langer HF,Pap T,Nieswandt B,Wiendl H,Chavakis T,Kleinschnitz C,Meuth SG
14-0401 was used in Flow cytometry/Cell sorting to study how immune activation by FXII is mediated by dendritic cells in a CD87-dependent manner, and involves alterations in intracellular cyclic AMP formation.
Wed May 18 00:00:00 EDT 2016
CXCL16-positive dendritic cells enhance invariant natural killer T cell-dependent IFNγ production and tumor control.
Oncoimmunology
Veinotte L,Gebremeskel S,Johnston B
14040182 was used in flow cytometry to study the contribution of CXCR6/CXCL16 interactions in glycolipid-dependent invariant natural killer cell activation and tumor control
Wed Jun 01 00:00:00 EDT 2016
Deficient for endoplasmic reticulum calcium sensors Stim1 and Stim2 affects aberrant antibody affinity maturation in B cells.
Oncotarget
Mao X,Zhang J,Han Y,Luan C,Hu Y,Hao Z,Chen M
14-0401 was used in Functional assays to determine the effect of calcium influx on antibody affinity maturation.
Tue Sep 20 00:00:00 EDT 2016
Allogeneic IgG combined with dendritic cell stimuli induce antitumour T-cell immunity.
Nature
Carmi Y,Spitzer MH,Linde IL,Burt BM,Prestwood TR,Perlman N,Davidson MG,Kenkel JA,Segal E,Pusapati GV,Bhattacharya N,Engleman EG
14-0401 was used in Flow cytometry/Cell sorting to find that allogeneic tumour rejection is initiated in mice by naturally occurring tumour-binding IgG antibodies.
Thu May 07 00:00:00 EDT 2015
The neurotrophic receptor Ntrk2 directs lymphoid tissue neovascularization during Leishmania donovani infection.
PLoS pathogens
Dalton JE,Glover AC,Hoodless L,Lim EK,Beattie L,Kirby A,Kaye PM
14-0401 was used in Flow cytometry/Cell sorting to investigate how Ntrk2 plays a role in the pathologic remodeling of the spleen that accompanies chronic infection.
Sun Feb 01 00:00:00 EST 2015
Natural IgM Switches the Function of Lipopolysaccharide-Activated Murine Bone Marrow-Derived Dendritic Cells to a Regulatory Dendritic Cell That Suppresses Innate Inflammation.
Journal of immunology (Baltimore, Md. : 1950)
Lobo PI,Schlegel KH,Bajwa A,Huang L,Kurmaeva E,Wang B,Ye H,Tedder TF,Kinsey GR,Okusa MD
14-0401 was used in Flow cytometry/Cell sorting to investigate how natural IgM anti-leukocyte Abs can switch BMDC to a regulatory phenotype despite the presence of LPS that ordinarily induces BMDC maturation.
Tue Dec 01 00:00:00 EST 2015
Adjuvants may reduce in vivo transfection levels for DNA vaccination in mice leading to reduced antigen-specific CD8+ T cell responses.
Human vaccines & immunotherapeutics
Rose AH,Hoffmann FW,Hara JH,Urschitz J,Moisyadi S,Hoffmann PR,Bertino P
Published figure using CD40 monoclonal antibody (Product # 14-0401-82) in Flow Cytometry
Mon May 16 00:00:00 EDT 2016
Detection of rare antigen-presenting cells through T cell-intrinsic meandering motility, mediated by Myo1g.
Cell
Gérard A,Patino-Lopez G,Beemiller P,Nambiar R,Ben-Aissa K,Liu Y,Totah FJ,Tyska MJ,Shaw S,Krummel MF
14-0401 was used in Immunofluorescence to show that Myo1g-mediated T cell-intrinsic meandering motility search are critical for the detection of rare cognate antigen-presenting cells.
Thu Jul 31 00:00:00 EDT 2014
IL-4 regulates Bim expression and promotes B cell maturation in synergy with BAFF conferring resistance to cell death at negative selection checkpoints.
Journal of immunology (Baltimore, Md. : 1950)
Granato A,Hayashi EA,Baptista BJ,Bellio M,Nobrega A
14-0401 was used in Flow cytometry/Cell sorting to analyze the effect of IL-4 on B cell maturation, and its influence on BCR-mediated negative selection.
Sun Jun 15 00:00:00 EDT 2014
Bcl-xL regulates CD1d-mediated antigen presentation to NKT cells by altering CD1d trafficking through the endocytic pathway.
Journal of immunology (Baltimore, Md. : 1950)
Subrahmanyam PB,Carey GB,Webb TJ
14-0401 was used in Flow cytometry/Cell sorting to demonstrate that Bcl-xL regulates CD1d-mediated Ag processing and presentation to natural killer T cells.
Mon Sep 01 00:00:00 EDT 2014
Nizatidine, a small molecular compound, enhances killed H5N1 vaccine cell-mediated responses and protects mice from lethal viral challenge.
Human vaccines & immunotherapeutics
Wang S,Wu B,Xue J,Wang M,Chen R,Wang B
Published figure using CD40 monoclonal antibody (Product # 14-0401-82) in Flow Cytometry
Mon Jan 05 00:00:00 EST 2015
Deficiency of autophagy in dendritic cells protects against experimental autoimmune encephalomyelitis.
The Journal of biological chemistry
Bhattacharya A,Parillon X,Zeng S,Han S,Eissa NT
Published figure using CD40 monoclonal antibody (Product # 14-0401-82) in Flow Cytometry
Fri Sep 19 00:00:00 EDT 2014
Enhanced cross-presentation and improved CD8+ T cell responses after mannosylation of synthetic long peptides in mice.
PloS one
Rauen J,Kreer C,Paillard A,van Duikeren S,Benckhuijsen WE,Camps MG,Valentijn AR,Ossendorp F,Drijfhout JW,Arens R,Burgdorf S
14-0401 was used in Flow cytometry/Cell sorting to demonstrate that mannosylation of synthetic long peptides augments the induction of a cytotoxic T-cell response.
Mon Oct 26 00:00:00 EDT 2015
Interferon-γ induces expression of MHC class II on intestinal epithelial cells and protects mice from colitis.
PloS one
Thelemann C,Eren RO,Coutaz M,Brasseit J,Bouzourene H,Rosa M,Duval A,Lavanchy C,Mack V,Mueller C,Reith W,Acha-Orbea H
14-0401 was used in Flow cytometry/Cell sorting to investigate how epithelial MHCII expression is induced and how a deficiency in inducible epithelial MHCII expression alters susceptibility to colitis and the outcome of colon-specific immune responses.
Mon Dec 22 00:00:00 EST 2014
Control of Toll-like receptor-mediated T cell-independent type 1 antibody responses by the inducible nuclear protein IκB-ζ.
The Journal of biological chemistry
Hanihara-Tatsuzawa F,Miura H,Kobayashi S,Isagawa T,Okuma A,Manabe I,MaruYama T
14-0401-81 was used in Functional assays to indicate that IκB-ζ regulates TLR-mediated class switch recombination by inducing activation-induced cytidine deaminase.
Fri Nov 07 00:00:00 EST 2014
Dysregulated cytokine production by dendritic cells modulates B cell responses in the NZM2410 mouse model of lupus.
PloS one
Sang A,Zheng YY,Yin Y,Dozmorov I,Li H,Hsu HC,Mountz JD,Morel L
14-0401 was used in an ELISA assay to show that the lupus prone mice autoimmune genetic background induces the production of B cell-modulating inflammatory cytokines by dendritic cells.
Fri Apr 24 00:00:00 EDT 2015
Liver gene therapy by lentiviral vectors reverses anti-factor IX pre-existing immunity in haemophilic mice.
EMBO molecular medicine
Annoni A,Cantore A,Della Valle P,Goudy K,Akbarpour M,Russo F,Bartolaccini S,D'Angelo A,Roncarolo MG,Naldini L
14-0401 was used in Flow cytometry/Cell sorting to position gene therapy as an attractive treatment option for inhibitors-positive haemophilic patients.
Fri Nov 01 00:00:00 EDT 2013
Characterization of an arachidonic acid-deficient (Fads1 knockout) mouse model.
Journal of lipid research
Fan YY,Monk JM,Hou TY,Callway E,Vincent L,Weeks B,Yang P,Chapkin RS
14-0401 was used in in vitro experiments to determine the utility of antagonising tissue arachidonic acid (AA) levels as a novel approach to suppress AA-derived eicosanoids.
Sun Jul 01 00:00:00 EDT 2012
Stromal cells' B7-1 is a key stimulatory molecule for interleukin-10 production by HOZOT, a multifunctional regulatory T-cell line.
Immunology and cell biology
Otani T,Tsuji-Takayama K,Okochi A,Yamamoto M,Takeuchi M,Yamasaki F,Nakamura S,Kibata M
14-0401 was used in Flow cytometry/Cell sorting to reveal that anti-mouse B7-1 Ab could effectively block IL-10 production, indicating a key role of the B7-1/CD28 pathway.
Tue Feb 01 00:00:00 EST 2011
TCA cycle inactivation in Staphylococcus aureus alters nitric oxide production in RAW 264.7 cells.
Molecular and cellular biochemistry
Massilamany C,Gangaplara A,Gardner DJ,Musser JM,Steffen D,Somerville GA,Reddy J
14-0401 was used in Flow cytometry/Cell sorting to study the mechanisms by which Staphylococci can evade innate immune responses and enhance their ability to survive in infected hosts.
Thu Sep 01 00:00:00 EDT 2011
Accumulation of eosinophils in intestine-draining mesenteric lymph nodes occurs after Trichuris muris infection.
Parasite immunology
Svensson M,Bell L,Little MC,DeSchoolmeester M,Locksley RM,Else KJ
14-0401-81 was used in Flow Cytometry to study the accumulation of eosinophils in intestine-draining mesenteric lymph nodes following Trichuris muris infection.
Sat Jan 01 00:00:00 EST 2011
Inhibition of B-cell activation by retinal pigment epithelium.
Investigative ophthalmology & visual science
Sugita S,Horie S,Yamada Y,Mochizuki M
14-0401-81 was used in Functional assays to determine whether retinal pigment epithelial (RPE) cells can inhibit B-cell activation in vitro, showing that B-cell proliferation was suppressed.
Mon Nov 01 00:00:00 EDT 2010
Rhipicephalus microplus salivary gland molecules induce differential CD86 expression in murine macrophages.
Parasites & vectors
Brake DK,Wikel SK,Tidwell JP,Pérez de León AA
14-0401 was used in Flow cytometry/Cell sorting to show that CD86 up-regulation is at least partially dependent on the ERK1/2 pathway and may serve to promote Th2 polarization of the immune response.
Fri Nov 05 00:00:00 EDT 2010
Lung interstitial macrophages alter dendritic cell functions to prevent airway allergy in mice.
The Journal of clinical investigation
Bedoret D,Wallemacq H,Marichal T,Desmet C,Quesada Calvo F,Henry E,Closset R,Dewals B,Thielen C,Gustin P,de Leval L,Van Rooijen N,Le Moine A,Vanderplasschen A,Cataldo D,Drion PV,Moser M,Lekeux P,Bureau F
14-0401 was used in Functional assays to reveal a crucial role for IMs in maintaining immune homeostasis in the respiratory tract.
Tue Dec 01 00:00:00 EST 2009
Annexin-1-deficient dendritic cells acquire a mature phenotype during differentiation.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology
Huggins A,Paschalidis N,Flower RJ,Perretti M,D'Acquisto F
14-0401 was used in Flow cytometry/Cell sorting to suggest that the inhibition of Anx-A1 expression in dendritic cells may be useful to modulate the adaptive immune response in pathogen-induced immune diseases.
Wed Apr 01 00:00:00 EDT 2009
Suppression of IgE B cells and IgE binding to Fc(epsilon)RI by gene therapy with single-chain anti-IgE.
Journal of immunology (Baltimore, Md. : 1950)
Ota T,Aoki-Ota M,Duong BH,Nemazee D
14-0401 was used in Flow cytometry/Cell sorting to reveal implications for the optimal design of safe and effective anti-IgE therapies and suggest that the IgE memory B cells may be targeted by such genetic Ab therapies.
Mon Jun 15 00:00:00 EDT 2009
B cell receptor-induced phosphorylation of Pyk2 and focal adhesion kinase involves integrins and the Rap GTPases and is required for B cell spreading.
The Journal of biological chemistry
Tse KW,Dang-Lawson M,Lee RL,Vong D,Bulic A,Buckbinder L,Gold MR
14-0401 was used in Western Blotting to demonstrate that BCR signalling regulates cell adhesion, cell morphology, and cell migration- crucial processes for B cell spreading.
Fri Aug 21 00:00:00 EDT 2009
Identification of regulatory functions for 4-1BB and 4-1BBL in myelopoiesis and the development of dendritic cells.
Nature immunology
Lee SW,Park Y,So T,Kwon BS,Cheroutre H,Mittler RS,Croft M
Published figure using CD40 monoclonal antibody (Product # 14-0401-82) in Flow Cytometry
Fri Aug 01 00:00:00 EDT 2008
Dynamics of lung macrophage activation in response to helminth infection.
Journal of leukocyte biology
Siracusa MC,Reece JJ,Urban JF,Scott AL
Published figure using CD40 monoclonal antibody (Product # 14-0401-82) in Flow Cytometry
Mon Dec 01 00:00:00 EST 2008
Activation-induced deaminase-mediated class switch recombination is blocked by anti-IgM signaling in a phosphatidylinositol 3-kinase-dependent fashion.
Molecular immunology
Heltemes-Harris LM,Gearhart PJ,Ghosh P,Longo DL
14-0401 was used in in vitro experiments to suggest that activation through the B cell receptor induces PI3K, which interferes with the function of AID.
Sat Mar 01 00:00:00 EST 2008
Regulation of class-switch recombination and plasma cell differentiation by phosphatidylinositol 3-kinase signaling.
Immunity
Omori SA,Cato MH,Anzelon-Mills A,Puri KD,Shapiro-Shelef M,Calame K,Rickert RC
14-0401 was used in Immunohistochemistry to demonstrate that phosphatidylinositol 3-kinase actively suppresses the onset and frequency of Class-switch recombination in primary B cells.
Sun Oct 01 00:00:00 EDT 2006
The B cell receptor promotes B cell activation and proliferation through a non-ITAM tyrosine in the Igalpha cytoplasmic domain.
Immunity
Patterson HC,Kraus M,Kim YM,Ploegh H,Rajewsky K
14-0401-81 was used in Functional assays to study the effects of a targeted mutation of Igalpha Y204 in splenic B cells.
Sat Jul 01 00:00:00 EDT 2006
Infected site-restricted Foxp3+ natural regulatory T cells are specific for microbial antigens.
The Journal of experimental medicine
Suffia IJ,Reckling SK,Piccirillo CA,Goldszmid RS,Belkaid Y
14-0401-81 was used in Flow Cytometry to study the antigenic specificity of natural regulatory T cells that accumulate at sites of chronic infection with Leishmania major in mice.
Mon Mar 20 00:00:00 EST 2006
