Product References
Protocol for PPP1R15A-inhibited mouse model establishment with subcutaneous B16F1 tumor and single-cell analysis.
STAR protocols
Wang R,Wang M,Pei S,Zhang Y,Guo S,Guo W,Wu Z,Wang H,Li Y,Zhu Y,Meng LH,Lang J,Jin G,Xiao Y,Hu L,Kong X
Published figure using CD8a monoclonal antibody (Product # 15-0081-82) in Flow Cytometry
Fri Dec 15 00:00:00 EST 2023
Chronic T cell proliferation in brains after stroke could interfere with the efficacy of immunotherapies.
The Journal of experimental medicine
Heindl S,Ricci A,Carofiglio O,Zhou Q,Arzberger T,Lenart N,Franzmeier N,Hortobagyi T,Nelson PT,Stowe AM,Denes A,Edbauer D,Liesz A
Published figure using CD8a monoclonal antibody (Product # 15-0081-82) in Flow Cytometry
Mon Aug 02 00:00:00 EDT 2021
γ-Tocotrienol-Loaded Liposomes for Radioprotection from Hematopoietic Side Effects Caused by Radiotherapeutic Drugs.
Journal of nuclear medicine : official publication, Society of Nuclear Medicine
Lee SG,Kalidindi TM,Lou H,Gangangari K,Punzalan B,Bitton A,Lee CJ,Vargas HA,Park S,Bodei L,Kharas MG,Singh VK,Kishore Pillarsetty NV,Larson SM
15-0081 was used in Flow cytometry/Cell sorting to report a novel radioprotector drug, a liposomal formulation of gamma-tocotrienol (GT3), or GT3-Nano for short, to mitigate bone marrow radiation damage during targeted radionuclide therapy (TRT).
Thu Apr 01 00:00:00 EDT 2021
A Biological Circuit Involving Mef2c, Mef2d, and Hdac9 Controls the Immunosuppressive Functions of CD4+Foxp3+ T-Regulatory Cells.
Frontiers in immunology
Di Giorgio E,Wang L,Xiong Y,Christensen LM,Akimova T,Han R,Samanta A,Trevisanut M,Brancolini C,Beier UH,Hancock WW
Published figure using CD8a monoclonal antibody (Product # 15-0081-82) in Flow Cytometry
Fri Dec 17 00:00:00 EST 2021
USP12 downregulation orchestrates a protumourigenic microenvironment and enhances lung tumour resistance to PD-1 blockade.
Nature communications
Yang Z,Xu G,Wang B,Liu Y,Zhang L,Jing T,Tang M,Xu X,Jiao K,Xiang L,Fu Y,Tang D,Zhang X,Jin W,Zhuang G,Zhao X,Liu Y
15-0081-82 was used in Flow Cytometry to show that the deubiquitinase USP12 is commonly downregulated in the KrasG12D-driven mouse lung tumour and human non-small cell lung cancer owing to the activation of AKT-mTOR signalling.
Wed Aug 11 00:00:00 EDT 2021
Local Sustained GM-CSF Delivery by Genetically Engineered Encapsulated Cells Enhanced Both Cellular and Humoral SARS-CoV-2 Spike-Specific Immune Response in an Experimental Murine Spike DNA Vaccination Model.
Vaccines
Vernet R,Charrier E,Cosset E,Fièvre S,Tomasello U,Grogg J,Mach N
Published figure using CD8a monoclonal antibody (Product # 15-0081-82) in Flow Cytometry
Mon May 10 00:00:00 EDT 2021
Cancer immunotherapy by NC410, a LAIR-2 Fc protein blocking human LAIR-collagen interaction.
eLife
Ramos MIP,Tian L,de Ruiter EJ,Song C,Paucarmayta A,Singh A,Elshof E,Vijver SV,Shaik J,Bosiacki J,Cusumano Z,Jensen C,Willumsen N,Karsdal MA,Liu L,Langermann S,Willems S,Flies D,Meyaard L
Published figure using CD8a monoclonal antibody (Product # 15-0081-82) in Flow Cytometry
Mon Jun 14 00:00:00 EDT 2021
BRCA1 Mutational Complementation Induces Synthetic Viability.
Molecular cell
Nacson J,Di Marcantonio D,Wang Y,Bernhardy AJ,Clausen E,Hua X,Cai KQ,Martinez E,Feng W,Callén E,Wu W,Gupta GP,Testa JR,Nussenzweig A,Sykes SM,Johnson N
15-0081-82 was used in Flow Cytometry to investigate the dual roles of BRCA1 in homologous recombination.
Thu Jun 04 00:00:00 EDT 2020
Sensing of endogenous nucleic acids by ZBP1 induces keratinocyte necroptosis and skin inflammation.
The Journal of experimental medicine
Devos M,Tanghe G,Gilbert B,Dierick E,Verheirstraeten M,Nemegeer J,de Reuver R,Lefebvre S,De Munck J,Rehwinkel J,Vandenabeele P,Declercq W,Maelfait J
Published figure using CD8a monoclonal antibody (Product # 15-0081-82) in Flow Cytometry
Mon Jul 06 00:00:00 EDT 2020
Glufosinate constrains synchronous and metachronous metastasis by promoting anti-tumor macrophages.
EMBO molecular medicine
Menga A,Serra M,Todisco S,Riera-Domingo C,Ammarah U,Ehling M,Palmieri EM,Di Noia MA,Gissi R,Favia M,Pierri CL,Porporato PE,Castegna A,Mazzone M
Published figure using CD8a monoclonal antibody (Product # 15-0081-82) in Flow Cytometry
Wed Oct 07 00:00:00 EDT 2020
Regulating colonic dendritic cells by commensal glycosylated large surface layer protein A to sustain gut homeostasis against pathogenic inflammation.
Mucosal immunology
Ge Y,Gong M,Zadeh M,Li J,Abbott JR,Li W,Morel L,Sonon R,Supekar NT,Azadi P,Wang Y,Jones DP,Li S,Mohamadzadeh M
15-0081 was used in Flow cytometry/Cell sorting to study the molecular mechanisms responsible for regulating gut homeostasis.
Wed Jan 01 00:00:00 EST 2020
Silencing IDO2 in dendritic cells: A novel strategy to strengthen cancer immunotherapy in a murine lung cancer model.
International journal of oncology
Liu Y,Xu P,Liu H,Fang C,Guo H,Chen X,Tan M,Zhang Y,Min W
15-0081-82 was used in Flow Cytometry to provide evidence that the silencing of the tryptophan rate‚limiting metabolic enzyme, IDO2, has the potential to enhance the efficacy of DC‚based cancer immunotherapy.
Sat Aug 01 00:00:00 EDT 2020
HDAC Inhibitor, CG-745, Enhances the Anti-Cancer Effect of Anti-PD-1 Immune Checkpoint Inhibitor by Modulation of the Immune Microenvironment.
Journal of Cancer
Kim YD,Park SM,Ha HC,Lee AR,Won H,Cha H,Cho S,Cho JM
Published figure using CD8a monoclonal antibody (Product # 15-0081-82) in Flow Cytometry
Mon Sep 28 00:00:00 EDT 2020
TIAM2S Mediates Serotonin Homeostasis and Provokes a Pro-Inflammatory Immune Microenvironment Permissive for Colorectal Tumorigenesis.
Cancers
Chan YL,Lai WC,Chen JS,Tseng JT,Chuang PC,Jou J,Lee CT,Sun HS
Published figure using CD8a monoclonal antibody (Product # 15-0081-82) in Flow Cytometry
Wed Jul 08 00:00:00 EDT 2020
The lysophospholipase D enzyme Gdpd3 is required to maintain chronic myelogenous leukaemia stem cells.
Nature communications
Naka K,Ochiai R,Matsubara E,Kondo C,Yang KM,Hoshii T,Araki M,Araki K,Sotomaru Y,Sasaki K,Mitani K,Kim DW,Ooshima A,Kim SJ
Published figure using CD8a monoclonal antibody (Product # 15-0081-82) in Flow Cytometry
Thu Sep 17 00:00:00 EDT 2020
RIPK3 and Caspase-1/11 Are Necessary for Optimal Antigen-Specific CD8 T Cell Response Elicited by Genetically Modified Listeria monocytogenes.
Frontiers in immunology
Rana A,de Almeida FC,Paico Montero HA,Gonzales Carazas MM,Bortoluci KR,Sad S,Amarante-Mendes GP
Published figure using CD8a monoclonal antibody (Product # 15-0081-82) in Flow Cytometry
Fri Mar 26 00:00:00 EDT 2021
Artificial Mini Dendritic Cells Boost T Cell-Based Immunotherapy for Ovarian Cancer.
Advanced science (Weinheim, Baden-Wurttemberg, Germany)
Cheng S,Xu C,Jin Y,Li Y,Zhong C,Ma J,Yang J,Zhang N,Li Y,Wang C,Yang Z,Wang Y
Published figure using CD8a monoclonal antibody (Product # 15-0081-82) in Flow Cytometry
Wed Apr 01 00:00:00 EDT 2020
Loss of testosterone impairs anti-tumor neutrophil function.
Nature communications
Markman JL,Porritt RA,Wakita D,Lane ME,Martinon D,Noval Rivas M,Luu M,Posadas EM,Crother TR,Arditi M
15-0081-82 was used in Flow cytometry/Cell sorting to show that in castrated male mice, neutrophil maturation and function are impaired, leading to elevated metastatic burden in two models of melanoma.
Tue Mar 31 00:00:00 EDT 2020
Loss of testosterone impairs anti-tumor neutrophil function.
Nature communications
Markman JL,Porritt RA,Wakita D,Lane ME,Martinon D,Noval Rivas M,Luu M,Posadas EM,Crother TR,Arditi M
15-0081-82 was used in Flow cytometry/Cell sorting to show that in castrated male mice, neutrophil maturation and function are impaired, leading to elevated metastatic burden in two models of melanoma.
Tue Mar 31 00:00:00 EDT 2020
Nuclear imaging-guided PD-L1 blockade therapy increases effectiveness of cancer immunotherapy.
Journal for immunotherapy of cancer
Gao H,Wu Y,Shi J,Zhang X,Liu T,Hu B,Jia B,Wan Y,Liu Z,Wang F
Published figure using CD8a monoclonal antibody (Product # 15-0081-82) in Flow Cytometry
Sun Nov 01 00:00:00 EDT 2020
Gasdermin D in macrophages restrains colitis by controlling cGAS-mediated inflammation.
Science advances
Ma C,Yang D,Wang B,Wu C,Wu Y,Li S,Liu X,Lassen K,Dai L,Yang S
Published figure using CD8a monoclonal antibody (Product # 15-0081-82) in Flow Cytometry
Fri May 01 00:00:00 EDT 2020
Plasma Cell Fate Is Orchestrated by Elaborate Changes in Genome Compartmentalization and Inter-chromosomal Hubs.
Cell reports
Bortnick A,He Z,Aubrey M,Chandra V,Denholtz M,Chen K,Lin YC,Murre C
15-0081 was used in Flow cytometry/Cell sorting to examine whether plasma cell development is also associated with changes in nuclear architecture.
Tue Apr 07 00:00:00 EDT 2020
Loss of FGFR3 Delays Acute Myeloid Leukemogenesis by Programming Weakly Pathogenic CD117-Positive Leukemia Stem-Like Cells.
Frontiers in pharmacology
Guo C,Ran Q,Sun C,Zhou T,Yang X,Zhang J,Pang S,Xiao Y
15-0081-82 was used in Flow Cytometry to find that FGFR3 had a novel regulatory mechanism for the stemness of LSCs in AML, and provided a promising anti-leukemia approach by interrupting FGFR3.
Tue Feb 16 00:00:00 EST 2021
ICOS agonism by JTX-2011 (vopratelimab) requires initial T cell priming and Fc cross-linking for optimal T cell activation and anti-tumor immunity in preclinical models.
PloS one
Hanson A,Elpek K,Duong E,Shallberg L,Fan M,Johnson C,Wallace M,Mabry GR,Sazinsky S,Pepper L,Shu CJ,Sathyanarayanan S,Zuerndorfer S,Simpson T,Gostissa M,Briskin M,Law D,Michaelson J,Harvey CJ
Published figure using CD8a monoclonal antibody (Product # 15-0081-82) in Flow Cytometry
Mon Nov 16 00:00:00 EST 2020
Specific targeting of IL-1β activity to CD8+ T cells allows for safe use as a vaccine adjuvant.
NPJ vaccines
Van Den Eeckhout B,Van Hoecke L,Burg E,Van Lint S,Peelman F,Kley N,Uzé G,Saelens X,Tavernier J,Gerlo S
Published figure using CD8a monoclonal antibody (Product # 15-0081-82) in Flow Cytometry
Tue Sep 19 00:00:00 EDT 2023
HyperTRIBE uncovers increased MUSASHI-2 RNA binding activity and differential regulation in leukemic stem cells.
Nature communications
Nguyen DTT,Lu Y,Chu KL,Yang X,Park SM,Choo ZN,Chin CR,Prieto C,Schurer A,Barin E,Savino AM,Gourkanti S,Patel P,Vu LP,Leslie CS,Kharas MG
15-0081 was used in Flow cytometry/Cell sorting to globally map the mRNA targets of the RBP MSI2 in mammalian adult normal and malignant stem cells.
Fri Apr 24 00:00:00 EDT 2020
CD8+ T cells induce cachexia during chronic viral infection.
Nature immunology
Baazim H,Schweiger M,Moschinger M,Xu H,Scherer T,Popa A,Gallage S,Ali A,Khamina K,Kosack L,Vilagos B,Smyth M,Lercher A,Friske J,Merkler D,Aderem A,Helbich TH,Heikenwälder M,Lang PA,Zechner R,Bergthaler A
15-0081-82 was used in Flow Cytometry to identify the role for CD8+ T cells in infection-associated cachexia.
Sat Jun 01 00:00:00 EDT 2019
Antiallodynic Effects of Cannabinoid Receptor 2 (CB2R) Agonists on Retrovirus Infection-Induced Neuropathic Pain.
Pain research & management
Sheng WS,Chauhan P,Hu S,Prasad S,Lokensgard JR
Published figure using CD8a monoclonal antibody (Product # 15-0081-82) in Flow Cytometry
Mon Dec 16 00:00:00 EST 2019
m6A RNA Methylation Maintains Hematopoietic Stem Cell Identity and Symmetric Commitment.
Cell reports
Cheng Y,Luo H,Izzo F,Pickering BF,Nguyen D,Myers R,Schurer A,Gourkanti S,Brüning JC,Vu LP,Jaffrey SR,Landau DA,Kharas MG
15-0081-82 was used in Flow cytometry/Cell sorting to indicate that RNA methylation controls symmetric commitment and cell identity of hematopoietic stem cells and may provide a general mechanism for how stem cells regulate differentiation fate choice.
Tue Aug 13 00:00:00 EDT 2019
N-Cadherin-Expressing Bone and Marrow Stromal Progenitor Cells Maintain Reserve Hematopoietic Stem Cells.
Cell reports
Zhao M,Tao F,Venkatraman A,Li Z,Smith SE,Unruh J,Chen S,Ward C,Qian P,Perry JM,Marshall H,Wang J,He XC,Li L
15-0081 was used in Flow cytometry/Cell sorting to report that N-cad+ cells were functional bone and marrow stromal progenitor cells, giving rise to osteoblasts, adipocytes, and chondrocytes both in vitro and in vivo.
Tue Jan 15 00:00:00 EST 2019
STAT1 is a sex-specific tumor suppressor in colitis-associated colorectal cancer.
Molecular oncology
Crnčec I,Modak M,Gordziel C,Svinka J,Scharf I,Moritsch S,Pathria P,Schlederer M,Kenner L,Timelthaler G,Müller M,Strobl B,Casanova E,Bayer E,Mohr T,Stöckl J,Friedrich K,Eferl R
Published figure using CD8a monoclonal antibody (Product # 15-0081-82) in Flow Cytometry
Sun Apr 01 00:00:00 EDT 2018
Inhibiting TrxR suppresses liver cancer by inducing apoptosis and eliciting potent antitumor immunity.
Oncology reports
Lei H,Wang G,Zhang J,Han Q
Published figure using CD8a monoclonal antibody (Product # 15-0081-82) in Flow Cytometry
Sat Dec 01 00:00:00 EST 2018
High fish oil diet promotes liver inflammation and activates the complement system.
Molecular medicine reports
Jin H,Yan C,Xiao T,Yan N,Xu J,Zhou L,Zhou X,Shao Q,Xia S
Tue May 01 00:00:00 EDT 2018
Sipa1 deficiency unleashes a host-immune mechanism eradicating chronic myelogenous leukemia-initiating cells.
Nature communications
Xu Y,Ikeda S,Sumida K,Yamamoto R,Tanaka H,Minato N
Published figure using CD8a monoclonal antibody (Product # 15-0081-82) in Flow Cytometry
Fri Mar 02 00:00:00 EST 2018
A stochastic epigenetic switch controls the dynamics of T-cell lineage commitment.
eLife
Ng KK,Yui MA,Mehta A,Siu S,Irwin B,Pease S,Hirose S,Elowitz MB,Rothenberg EV,Kueh HY
Published figure using CD8a monoclonal antibody (Product # 15-0081-82) in Flow Cytometry
Tue Nov 20 00:00:00 EST 2018
Differential requirement of kindlin-3 for T cell progenitor homing to the non-vascularized and vascularized thymus.
eLife
Moretti FA,Klapproth S,Ruppert R,Margraf A,Weber J,Pick R,Scheiermann C,Sperandio M,Fässler R,Moser M
Published figure using CD8a monoclonal antibody (Product # 15-0081-82) in Flow Cytometry
Thu Sep 06 00:00:00 EDT 2018
A protocol for generating induced T cells by reprogramming B cells in vivo.
Cell regeneration (London, England)
Weng Q,Hu F,Zhang M,Dong Y,Lv C,Wang Y,Liu X,Wang J
Published figure using CD8a monoclonal antibody (Product # 15-0081-82) in Flow Cytometry
Sat Sep 01 00:00:00 EDT 2018
Macrophage Depletion Protects against Cigarette Smoke-Induced Inflammatory Response in the Mouse Colon and Lung.
Frontiers in physiology
Lim D,Kim W,Lee C,Bae H,Kim J
Published figure using CD8a monoclonal antibody (Product # 15-0081-82) in Flow Cytometry
Wed Sep 30 00:00:00 EDT 2020
Loss of Nucleobindin-2 Causes Insulin Resistance in Obesity without Impacting Satiety or Adiposity.
Cell reports
Ravussin A,Youm YH,Sander J,Ryu S,Nguyen K,Varela L,Shulman GI,Sidorov S,Horvath TL,Schultze JL,Dixit VD
Published figure using CD8a monoclonal antibody (Product # 15-0081-82) in Flow Cytometry
Tue Jul 31 00:00:00 EDT 2018
Modifying the cancer-immune set point using vaccinia virus expressing re-designed interleukin-2.
Nature communications
Liu Z,Ge Y,Wang H,Ma C,Feist M,Ju S,Guo ZS,Bartlett DL
Published figure using CD8a monoclonal antibody (Product # 15-0081-82) in Flow Cytometry
Thu Nov 08 00:00:00 EST 2018
Microbiota Reconstitution Does Not Cause Bone Loss in Germ-Free Mice.
mSphere
Quach D,Collins F,Parameswaran N,McCabe L,Britton RA
Published figure using CD8a monoclonal antibody (Product # 15-0081-82) in Flow Cytometry
Wed Nov 20 00:00:00 EST 2019
Retinoid-Sensitive Epigenetic Regulation of the Hoxb Cluster Maintains Normal Hematopoiesis and Inhibits Leukemogenesis.
Cell stem cell
Qian P,De Kumar B,He XC,Nolte C,Gogol M,Ahn Y,Chen S,Li Z,Xu H,Perry JM,Hu D,Tao F,Zhao M,Han Y,Hall K,Peak A,Paulson A,Zhao C,Venkatraman A,Box A,Perera A,Haug JS,Parmely T,Li H,Krumlauf R,Li L
15-0081 was used in Flow cytometry/Cell sorting to demonstrate roles for retinoid signaling and the DERARE in maintaining HSCs and preventing leukemogenesis by coordinate regulation of Hoxb genes.
Thu May 03 00:00:00 EDT 2018
T cell immunity to Zika virus targets immunodominant epitopes that show cross-reactivity with other Flaviviruses.
Scientific reports
Reynolds CJ,Suleyman OM,Ortega-Prieto AM,Skelton JK,Bonnesoeur P,Blohm A,Carregaro V,Silva JS,James EA,Maillère B,Dorner M,Boyton RJ,Altmann DM
15-0081 was used in Flow cytometry/Cell sorting to show conservation of recognition across Flaviviruses, may encompass protective and/or pathogenic components and poses challenges to characterization of ZIKV protective immunity.
Fri Jan 12 00:00:00 EST 2018
Dual Strategies for Argonaute2-Mediated Biogenesis of Erythroid miRNAs Underlie Conserved Requirements for Slicing in Mammals.
Molecular cell
Jee D,Yang JS,Park SM,Farmer DT,Wen J,Chou T,Chow A,McManus MT,Kharas MG,Lai EC
15-0081-82 was used in flow cytometry to investigate erythroid miRNA biogenesis in mammalian slicing.
Thu Jan 18 00:00:00 EST 2018
Direct Activation of BAX by BTSA1 Overcomes Apoptosis Resistance in Acute Myeloid Leukemia.
Cancer cell
Reyna DE,Garner TP,Lopez A,Kopp F,Choudhary GS,Sridharan A,Narayanagari SR,Mitchell K,Dong B,Bartholdy BA,Walensky LD,Verma A,Steidl U,Gavathiotis E
15-0081 was used in Flow cytometry/Cell sorting to identify BTSA1, a pharmacologically optimised BAX activator that binds with high affinity and specificity to the N-terminal activation site and induces conformational changes to BAX leading to BAX-mediated apoptosis.
Mon Oct 09 00:00:00 EDT 2017
Adipose tissue B2 cells promote insulin resistance through leukotriene LTB4/LTB4R1 signaling.
The Journal of clinical investigation
Ying W,Wollam J,Ofrecio JM,Bandyopadhyay G,El Ouarrat D,Lee YS,Oh DY,Li P,Osborn O,Olefsky JM
Published figure using CD8a monoclonal antibody (Product # 15-0081-82) in Flow Cytometry
Wed Mar 01 00:00:00 EST 2017
Combined antiangiogenic and anti-PD-L1 therapy stimulates tumor immunity through HEV formation.
Science translational medicine
Allen E,Jabouille A,Rivera LB,Lodewijckx I,Missiaen R,Steri V,Feyen K,Tawney J,Hanahan D,Michael IP,Bergers G
Published figure using CD8a monoclonal antibody (Product # 15-0081-82) in Flow Cytometry
Wed Apr 12 00:00:00 EDT 2017
Egr2 and 3 control adaptive immune responses by temporally uncoupling expansion from T cell differentiation.
The Journal of experimental medicine
Miao T,Symonds ALJ,Singh R,Symonds JD,Ogbe A,Omodho B,Zhu B,Li S,Wang P
Published figure using CD8a monoclonal antibody (Product # 15-0081-82) in Flow Cytometry
Mon Jun 05 00:00:00 EDT 2017
A New Adjuvant MTOM Mediates Mycobacterium tuberculosis Subunit Vaccine to Enhance Th1-Type T Cell Immune Responses and IL-2+ T Cells.
Frontiers in immunology
Yu Q,Wang X,Fan X
Published figure using CD8a monoclonal antibody (Product # 15-0081-82) in Flow Cytometry
Wed Nov 20 00:00:00 EST 2019
Betulin from Hedyotis hedyotidea ameliorates concanavalin A-induced and T cell-mediated autoimmune hepatitis in mice.
Acta pharmacologica Sinica
Zhou YQ,Weng XF,Dou R,Tan XS,Zhang TT,Fang JB,Wu XW
Published figure using CD8a monoclonal antibody (Product # 15-0081-82) in Flow Cytometry
Wed Feb 01 00:00:00 EST 2017
Role of Triggering Receptor Expressed on Myeloid Cell-1 Expression in Mammalian Target of Rapamycin Modulation of CD8+ T-cell Differentiation during the Immune Response to Invasive Pulmonary Aspergillosis.
Chinese medical journal
Cui N,Wang H,Su LX,Zhang JH,Long Y,Liu DW
Published figure using CD8a monoclonal antibody (Product # 15-0081-82) in Flow Cytometry
Sat May 20 00:00:00 EDT 2017
Immunological phenotype of the murine Lrba knockout.
Immunology and cell biology
Gámez-Díaz L,Neumann J,Jäger F,Proietti M,Felber F,Soulas-Sprauel P,Perruzza L,Grassi F,Kögl T,Aichele P,Kilimann M,Grimbacher B,Jung S
Published figure using CD8a monoclonal antibody (Product # 15-0081-82) in Flow Cytometry
Sun Oct 01 00:00:00 EDT 2017
ADAR1 deletion induces NFκB and interferon signaling dependent liver inflammation and fibrosis.
RNA biology
Ben-Shoshan SO,Kagan P,Sultan M,Barabash Z,Dor C,Jacob-Hirsch J,Harmelin A,Pappo O,Marcu-Malina V,Ben-Ari Z,Amariglio N,Rechavi G,Goldstein I,Safran M
Published figure using CD8a monoclonal antibody (Product # 15-0081-82) in Flow Cytometry
Thu May 04 00:00:00 EDT 2017
IL-2/Anti-IL-2 Complex Attenuates Inflammation and BBB Disruption in Mice Subjected to Traumatic Brain Injury.
Frontiers in neurology
Gao W,Li F,Zhou Z,Xu X,Wu Y,Zhou S,Yin D,Sun D,Xiong J,Jiang R,Zhang J
Published figure using CD8a monoclonal antibody (Product # 15-0081-82) in Flow Cytometry
Thu Oct 01 00:00:00 EDT 2020
Calreticulin is an effective immunologic adjuvant to tumor-associated antigens.
Experimental and therapeutic medicine
Wang J,Gao ZP,Qin S,Liu CB,Zou LL
Published figure using CD8a monoclonal antibody (Product # 15-0081-82) in Flow Cytometry
Sun Oct 01 00:00:00 EDT 2017
Transient Treg depletion enhances therapeutic anti-cancer vaccination.
Immunity, inflammation and disease
Fisher SA,Aston WJ,Chee J,Khong A,Cleaver AL,Solin JN,Ma S,Lesterhuis WJ,Dick I,Holt RA,Creaney J,Boon L,Robinson B,Lake RA
Published figure using CD8a monoclonal antibody (Product # 15-0081-82) in Flow Cytometry
Wed Mar 01 00:00:00 EST 2017
Targeted calcium influx boosts cytotoxic T lymphocyte function in the tumour microenvironment.
Nature communications
Kim KD,Bae S,Capece T,Nedelkovska H,de Rubio RG,Smrcka AV,Jun CD,Jung W,Park B,Kim TI,Kim M
Published figure using CD8a monoclonal antibody (Product # 15-0081-82) in Flow Cytometry
Mon May 15 00:00:00 EDT 2017
Location of tumor affects local and distant immune cell type and number.
Immunity, inflammation and disease
Hensel JA,Khattar V,Ashton R,Lee C,Siegal GP,Ponnazhagan S
Published figure using CD8a monoclonal antibody (Product # 15-0081-82) in Flow Cytometry
Wed Mar 01 00:00:00 EST 2017
Isolation of cell type-specific apoptotic bodies by fluorescence-activated cell sorting.
Scientific reports
Atkin-Smith GK,Paone S,Zanker DJ,Duan M,Phan TK,Chen W,Hulett MD,Poon IK
Published figure using CD8a monoclonal antibody (Product # 15-0081-82) in Flow Cytometry
Fri Jan 06 00:00:00 EST 2017
Identification of inhibitors of myeloid-derived suppressor cells activity through phenotypic chemical screening.
Oncoimmunology
Schröder M,Loos S,Naumann SK,Bachran C,Krötschel M,Umansky V,Helming L,Swee LK
Published figure using CD8a monoclonal antibody (Product # 15-0081-82) in Flow Cytometry
Tue Jan 12 00:00:00 EST 2021
IL-12 Influence mTOR to Modulate CD8+ T Cells Differentiation through T-bet and Eomesodermin in Response to Invasive Pulmonary Aspergillosis.
International journal of medical sciences
Wang H,Li J,Han Q,Yang F,Xiao Y,Xiao M,Xu Y,Su L,Cui N,Liu D
Published figure using CD8a monoclonal antibody (Product # 15-0081-82) in Flow Cytometry
Mon May 21 00:00:00 EDT 2018
Tristetraprolin inhibits macrophage IL-27-induced activation of antitumour cytotoxic T cell responses.
Nature communications
Wang Q,Ning H,Peng H,Wei L,Hou R,Hoft DF,Liu J
Published figure using CD8a monoclonal antibody (Product # 15-0081-82) in Flow Cytometry
Wed Oct 11 00:00:00 EDT 2017
IL-7-dependent STAT1 activation limits homeostatic CD4+ T cell expansion.
JCI insight
Le Saout C,Luckey MA,Villarino AV,Smith M,Hasley RB,Myers TG,Imamichi H,Park JH,O'Shea JJ,Lane HC,Catalfamo M
Published figure using CD8a monoclonal antibody (Product # 15-0081-82) in Flow Cytometry
Thu Nov 16 00:00:00 EST 2017
Potent single-domain antibodies that arrest respiratory syncytial virus fusion protein in its prefusion state.
Nature communications
Rossey I,Gilman MS,Kabeche SC,Sedeyn K,Wrapp D,Kanekiyo M,Chen M,Mas V,Spitaels J,Melero JA,Graham BS,Schepens B,McLellan JS,Saelens X
Published figure using CD8a monoclonal antibody (Product # 15-0081-82) in Flow Cytometry
Mon Feb 13 00:00:00 EST 2017
A Multistage Subunit Vaccine Effectively Protects Mice Against Primary Progressive Tuberculosis, Latency and Reactivation.
EBioMedicine
Ma J,Teng X,Wang X,Fan X,Wu Y,Tian M,Zhou Z,Li L
Published figure using CD8a monoclonal antibody (Product # 15-0081-82) in Flow Cytometry
Tue Aug 01 00:00:00 EDT 2017
Cytokine and hormonal regulation of bone marrow immune cell Wnt10b expression.
PloS one
Collins FL,Rios-Arce ND,McCabe LR,Parameswaran N
15-0081 was used in Flow cytometry/Cell sorting to determine the potential regulation of Wnt10b by estrogen and TNFα, showing regulation of expression by cytokines and hormones.
Mon Oct 09 00:00:00 EDT 2017
Metabolic maintenance of cell asymmetry following division in activated T lymphocytes.
Nature
Verbist KC,Guy CS,Milasta S,Liedmann S,Kamiński MM,Wang R,Green DR
Published figure using CD8a monoclonal antibody (Product # 15-0081-82) in Flow Cytometry
Thu Apr 21 00:00:00 EDT 2016
The Deubiquitinase OTULIN Is an Essential Negative Regulator of Inflammation and Autoimmunity.
Cell
Damgaard RB,Walker JA,Marco-Casanova P,Morgan NV,Titheradge HL,Elliott PR,McHale D,Maher ER,McKenzie ANJ,Komander D
Published figure using CD8a monoclonal antibody (Product # 15-0081-82) in Flow Cytometry
Thu Aug 25 00:00:00 EDT 2016
Maternal-Derived Hepatitis B Virus e Antigen Alters Macrophage Function in Offspring to Drive Viral Persistence after Vertical Transmission.
Immunity
Tian Y,Kuo CF,Akbari O,Ou JH
Published figure using CD8a monoclonal antibody (Product # 15-0081-82) in Flow Cytometry
Tue May 17 00:00:00 EDT 2016
Oligodendrocyte death results in immune-mediated CNS demyelination.
Nature neuroscience
Traka M,Podojil JR,McCarthy DP,Miller SD,Popko B
Published figure using CD8a monoclonal antibody (Product # 15-0081-82) in Flow Cytometry
Fri Jan 01 00:00:00 EST 2016
Neutrophil Extracellular Traps Enhance Early Inflammatory Response in Sendai Virus-Induced Asthma Phenotype.
Frontiers in immunology
Akk A,Springer LE,Pham CT
Published figure using CD8a monoclonal antibody (Product # 15-0081-82) in Flow Cytometry
Mon Sep 12 00:00:00 EDT 2016
Opposite Effects of Coinjection and Distant Injection of Mesenchymal Stem Cells on Breast Tumor Cell Growth.
Stem cells translational medicine
Zheng H,Zou W,Shen J,Xu L,Wang S,Fu YX,Fan W
Published figure using CD8a monoclonal antibody (Product # 15-0081-82) in Flow Cytometry
Thu Sep 01 00:00:00 EDT 2016
PRDM14 promotes RAG-dependent Notch1 driver mutations in mouse T-ALL.
Biology open
Carofino BL,Ayanga B,Tracey LJ,Brooke-Bisschop T,Justice MJ
Published figure using CD8a monoclonal antibody (Product # 15-0081-82) in Flow Cytometry
Sun May 15 00:00:00 EDT 2016
Stromal senescence establishes an immunosuppressive microenvironment that drives tumorigenesis.
Nature communications
Ruhland MK,Loza AJ,Capietto AH,Luo X,Knolhoff BL,Flanagan KC,Belt BA,Alspach E,Leahy K,Luo J,Schaffer A,Edwards JR,Longmore G,Faccio R,DeNardo DG,Stewart SA
Published figure using CD8a monoclonal antibody (Product # 15-0081-82) in Flow Cytometry
Wed Jun 08 00:00:00 EDT 2016
Epigallocatechin-3-gallate (EGCG) inhibits imiquimod-induced psoriasis-like inflammation of BALB/c mice.
BMC complementary and alternative medicine
Zhang S,Liu X,Mei L,Wang H,Fang F
Published figure using CD8a monoclonal antibody (Product # 15-0081-82) in Flow Cytometry
Wed Aug 31 00:00:00 EDT 2016
Discovery of a Metastatic Immune Escape Mechanism Initiated by the Loss of Expression of the Tumour Biomarker Interleukin-33.
Scientific reports
Saranchova I,Han J,Huang H,Fenninger F,Choi KB,Munro L,Pfeifer C,Welch I,Wyatt AW,Fazli L,Gleave ME,Jefferies WA
Published figure using CD8a monoclonal antibody (Product # 15-0081-82) in Flow Cytometry
Tue Sep 13 00:00:00 EDT 2016
Exploring the induction of preproinsulin-specific Foxp3(+) CD4(+) Treg cells that inhibit CD8(+) T cell-mediated autoimmune diabetes by DNA vaccination.
Scientific reports
Stifter K,Schuster C,Schlosser M,Boehm BO,Schirmbeck R
Published figure using CD8a monoclonal antibody (Product # 15-0081-82) in Flow Cytometry
Mon Jul 11 00:00:00 EDT 2016
Photothermal therapy with immune-adjuvant nanoparticles together with checkpoint blockade for effective cancer immunotherapy.
Nature communications
Chen Q,Xu L,Liang C,Wang C,Peng R,Liu Z
Published figure using CD8a monoclonal antibody (Product # 15-0081-82) in Flow Cytometry
Fri Oct 21 00:00:00 EDT 2016
IL-15 signaling promotes adoptive effector T-cell survival and memory formation in irradiation-induced lymphopenia.
Cell & bioscience
Xu A,Bhanumathy KK,Wu J,Ye Z,Freywald A,Leary SC,Li R,Xiang J
15-0081 was used in Flow cytometry/Cell sorting to investigate the mechanism for adoptively transferred effector T-cell survival and memory formation.
Mon May 09 00:00:00 EDT 2016
Alkylator-Induced and Patient-Derived Xenograft Mouse Models of Therapy-Related Myeloid Neoplasms Model Clinical Disease and Suggest the Presence of Multiple Cell Subpopulations with Leukemia Stem Cell Activity.
PloS one
Jonas BA,Johnson C,Gratzinger D,Majeti R
15-0081 was used in Flow cytometry/Cell sorting to report several new t-AML/MDS mouse models that could potentially be used to further define disease pathogenesis and test novel therapeutics.
Wed Jul 26 00:00:00 EDT 2017
Injectable, spontaneously assembling, inorganic scaffolds modulate immune cells in vivo and increase vaccine efficacy.
Nature biotechnology
Kim J,Li WA,Choi Y,Lewin SA,Verbeke CS,Dranoff G,Mooney DJ
Published figure using CD8a monoclonal antibody (Product # 15-0081-82) in Flow Cytometry
Thu Jan 01 00:00:00 EST 2015
FOXP3+ regulatory T cell development and function require histone/protein deacetylase 3.
The Journal of clinical investigation
Wang L,Liu Y,Han R,Beier UH,Bhatti TR,Akimova T,Greene MI,Hiebert SW,Hancock WW
Published figure using CD8a monoclonal antibody (Product # 15-0081-82) in Flow Cytometry
Mon Mar 02 00:00:00 EST 2015
Atypical chemokine receptor 1 deficiency reduces atherogenesis in ApoE-knockout mice.
Cardiovascular research
Wan W,Liu Q,Lionakis MS,Marino AP,Anderson SA,Swamydas M,Murphy PM
Published figure using CD8a monoclonal antibody (Product # 15-0081-82) in Flow Cytometry
Mon Jun 01 00:00:00 EDT 2015
MHC-mismatched mixed chimerism augments thymic regulatory T-cell production and prevents relapse of EAE in mice.
Proceedings of the National Academy of Sciences of the United States of America
Wu L,Li N,Zhang M,Xue SL,Cassady K,Lin Q,Riggs AD,Zeng D
Published figure using CD8a monoclonal antibody (Product # 15-0081-82) in Flow Cytometry
Tue Dec 29 00:00:00 EST 2015
CD31 signals confer immune privilege to the vascular endothelium.
Proceedings of the National Academy of Sciences of the United States of America
Cheung K,Ma L,Wang G,Coe D,Ferro R,Falasca M,Buckley CD,Mauro C,Marelli-Berg FM
Published figure using CD8a monoclonal antibody (Product # 15-0081-82) in Flow Cytometry
Tue Oct 27 00:00:00 EDT 2015
Single-Dose CpG Immunization Protects Against a Heterosubtypic Challenge and Generates Antigen-Specific Memory T Cells.
Frontiers in immunology
Vogel AJ,Brown DM
Published figure using CD8a monoclonal antibody (Product # 15-0081-82) in Flow Cytometry
Fri Jul 10 00:00:00 EDT 2015
Mice lacking Axl and Mer tyrosine kinase receptors are susceptible to experimental autoimmune orchitis induction.
Immunology and cell biology
Li N,Liu Z,Zhang Y,Chen Q,Liu P,Cheng CY,Lee WM,Chen Y,Han D
15-0081 was used in Flow cytometry/Cell sorting to indicate that Axl and Mer receptors cooperatively regulate the systemic immune tolerance to male germ cell antigens.
Sun Mar 01 00:00:00 EST 2015
A tumor lysate is an effective vaccine antigen for the stimulation of CD4(+) T-cell function and subsequent induction of antitumor immunity mediated by CD8(+) T cells.
Cancer biology & therapy
Kawahara M,Takaku H
Published figure using CD8a monoclonal antibody (Product # 15-0081-82) in Flow Cytometry
Mon Sep 12 00:00:00 EDT 2016
Adjuvants may reduce in vivo transfection levels for DNA vaccination in mice leading to reduced antigen-specific CD8+ T cell responses.
Human vaccines & immunotherapeutics
Rose AH,Hoffmann FW,Hara JH,Urschitz J,Moisyadi S,Hoffmann PR,Bertino P
Published figure using CD8a monoclonal antibody (Product # 15-0081-82) in Flow Cytometry
Mon May 16 00:00:00 EDT 2016
Immunogenicity and protective efficacy of DMT liposome-adjuvanted tuberculosis subunit CTT3H vaccine.
Human vaccines & immunotherapeutics
Teng X,Tian M,Li J,Tan S,Yuan X,Yu Q,Jing Y,Zhang Z,Yue T,Zhou L,Fan X
Published figure using CD8a monoclonal antibody (Product # 15-0081-82) in Flow Cytometry
Fri Mar 11 00:00:00 EST 2016
Favorable alteration of tumor microenvironment by immunomodulatory cytokines for efficient T-cell therapy in solid tumors.
PloS one
Tähtinen S,Kaikkonen S,Merisalo-Soikkeli M,Grönberg-Vähä-Koskela S,Kanerva A,Parviainen S,Vähä-Koskela M,Hemminki A
Published figure using CD8a monoclonal antibody (Product # 15-0081-82) in Flow Cytometry
Thu Apr 28 00:00:00 EDT 2016
MFG-E8 Is Critical for Embryonic Stem Cell-Mediated T Cell Immunomodulation.
Stem cell reports
Tan Y,AlKhamees B,Jia D,Li L,Couture JF,Figeys D,Jinushi M,Wang L
Published figure using CD8a monoclonal antibody (Product # 15-0081-82) in Flow Cytometry
Tue Nov 10 00:00:00 EST 2015
Near-infrared photoactivatable control of Ca(2+) signaling and optogenetic immunomodulation.
eLife
He L,Zhang Y,Ma G,Tan P,Li Z,Zang S,Wu X,Jing J,Fang S,Zhou L,Wang Y,Huang Y,Hogan PG,Han G,Zhou Y
Published figure using CD8a monoclonal antibody (Product # 15-0081-82) in Flow Cytometry
Tue Dec 08 00:00:00 EST 2015
Recombinant adeno-vaccine expressing enterovirus 71-like particles against hand, foot, and mouth disease.
PLoS neglected tropical diseases
Tsou YL,Lin YW,Shao HY,Yu SL,Wu SR,Lin HY,Liu CC,Huang C,Chong P,Chow YH
15-0081 was used in Flow cytometry/Cell sorting to develop a recombinant adenovirus Ad-EVVLP for the treatment of hand, foot and mouth disease, providing a possible vaccine for future immunisation against the disease.
Wed Apr 01 00:00:00 EDT 2015
Sleep disruption impairs haematopoietic stem cell transplantation in mice.
Nature communications
Rolls A,Pang WW,Ibarra I,Colas D,Bonnavion P,Korin B,Heller HC,Weissman IL,de Lecea L
15-0081 was used in Flow cytometry/Cell sorting to provide insights into cellular and molecular mechanisms underlying the effects of sleep deprivation on HSCs.
Wed Oct 14 00:00:00 EDT 2015
Iron prevents the development of experimental cerebral malaria by attenuating CXCR3-mediated T cell chemotaxis.
PloS one
Van Den Ham KM,Shio MT,Rainone A,Fournier S,Krawczyk CM,Olivier M
15-0081 was used in Flow cytometry/Cell sorting to study the effect of iron in attenuating CXCR3-mediated T cell chemotaxis and migration to the brain and therefore inhibiting Experimental Cerebral Malaria pathology.
Thu Jan 21 00:00:00 EST 2016
CCR10 regulates balanced maintenance and function of resident regulatory and effector T cells to promote immune homeostasis in the skin.
The Journal of allergy and clinical immunology
Xia M,Hu S,Fu Y,Jin W,Yi Q,Matsui Y,Yang J,McDowell MA,Sarkar S,Kalia V,Xiong N
15-0081 was used in Flow cytometry/Cell sorting to investigate the functional importance of CCR10/CCL27 in vivo, showing that CCR10 regulates maintenance and function of regulatory and effector T cells to promote immune homeostasis.
Mon Sep 01 00:00:00 EDT 2014
Immunosuppressive effect of compound K on islet transplantation in an STZ-induced diabetic mouse model.
Diabetes
Ma PF,Jiang J,Gao C,Cheng PP,Li JL,Huang X,Lin YY,Li Q,Peng YZ,Cai MC,Shao W,Zhu Q,Han S,Qin Q,Xia JJ,Qi ZQ
15-0081 was used in Flow cytometry/Cell sorting to investigate the therapeutic effect of Cpd K in diabetic mice.
Wed Oct 01 00:00:00 EDT 2014
CCR1 inhibition ameliorates the progression of lupus nephritis in NZB/W mice.
Journal of immunology (Baltimore, Md. : 1950)
Bignon A,Gaudin F,Hémon P,Tharinger H,Mayol K,Walzer T,Loetscher P,Peuchmaur M,Berrebi D,Balabanian K
15-0081 was used in Flow cytometry/Cell sorting to define a pivotal role for CCR4 in the recruitment of T and mononuclear phagocyte cells to inflamed kidneys of lupus-prone mice.
Sat Feb 01 00:00:00 EST 2014
Regulatory T cells shape the resident memory T cell response to virus infection in the tissues.
Journal of immunology (Baltimore, Md. : 1950)
Graham JB,Da Costa A,Lund JM
15-0081 was used in Flow cytometry/Cell sorting to demonstrate that Treg-dependent production of TGF-β results in increased expression of CD103 on CD8(+) T cells.
Wed Jan 15 00:00:00 EST 2014
Tumor-promoting role of TGFβ1 signaling in ultraviolet B-induced skin carcinogenesis is associated with cutaneous inflammation and lymph node migration of dermal dendritic cells.
Carcinogenesis
Ravindran A,Mohammed J,Gunderson AJ,Cui X,Glick AB
15-0081 was used in Flow cytometry/Cell sorting to study how TGFβ1 signalling has a tumour-promoting role in UVB-induced skin carcinogenesis, which is mediated in part through its role in UVB-induced migration of dDC and cutaneous inflammation.
Tue Apr 01 00:00:00 EDT 2014
A new animal model of spontaneous autoimmune peripheral polyneuropathy: implications for Guillain-Barré syndrome.
Acta neuropathologica communications
Yang M,Rainone A,Shi XQ,Fournier S,Zhang J
Published figure using CD8a monoclonal antibody (Product # 15-0081-82) in Flow Cytometry
Wed Jan 08 00:00:00 EST 2014
Simultaneous inhibition of T helper 2 and T regulatory cell differentiation by small molecules enhances Bacillus Calmette-Guerin vaccine efficacy against tuberculosis.
The Journal of biological chemistry
Bhattacharya D,Dwivedi VP,Kumar S,Reddy MC,Van Kaer L,Moodley P,Das G
15-0081 was used in Flow cytometry/Cell sorting to study the inhibition of Th2 cells and Tregs and the subsequent enhancement of the BCG vaccine efficacy.
Fri Nov 28 00:00:00 EST 2014
Deficiency of autophagy in dendritic cells protects against experimental autoimmune encephalomyelitis.
The Journal of biological chemistry
Bhattacharya A,Parillon X,Zeng S,Han S,Eissa NT
Published figure using CD8a monoclonal antibody (Product # 15-0081-82) in Flow Cytometry
Fri Sep 19 00:00:00 EDT 2014
Usp16 contributes to somatic stem-cell defects in Down's syndrome.
Nature
Adorno M,Sikandar S,Mitra SS,Kuo A,Nicolis Di Robilant B,Haro-Acosta V,Ouadah Y,Quarta M,Rodriguez J,Qian D,Reddy VM,Cheshier S,Garner CC,Clarke MF
15-0081 was used in Flow cytometry/Cell sorting to demonstrate a role for USP16 in antagonising the self-renewal and senescence pathways in Down's syndrome.
Thu Sep 19 00:00:00 EDT 2013
FOXO3A directs a protective autophagy program in haematopoietic stem cells.
Nature
Warr MR,Binnewies M,Flach J,Reynaud D,Garg T,Malhotra R,Debnath J,Passegué E
15-0081 was used in Flow cytometry/Cell sorting to show how FOXO3A directs a protective autophagy program in haematopoietic stem cells.
Thu Feb 21 00:00:00 EST 2013
Mutual expression of the transcription factors Runx3 and ThPOK regulates intestinal CD4⁺ T cell immunity.
Nature immunology
Reis BS,Rogoz A,Costa-Pinto FA,Taniuchi I,Mucida D
Published figure using CD8a monoclonal antibody (Product # 15-0081-82) in Flow Cytometry
Fri Mar 01 00:00:00 EST 2013
Dose-dense chemotherapy improves mechanisms of antitumor immune response.
Cancer research
Chang CL,Hsu YT,Wu CC,Lai YZ,Wang C,Yang YC,Wu TC,Hung CF
Published figure using CD8a monoclonal antibody (Product # 15-0081-82) in Flow Cytometry
Tue Jan 01 00:00:00 EST 2013
Genetic deletion of chemokine receptor Ccr7 exacerbates atherogenesis in ApoE-deficient mice.
Cardiovascular research
Wan W,Lionakis MS,Liu Q,Roffê E,Murphy PM
Published figure using CD8a monoclonal antibody (Product # 15-0081-82) in Flow Cytometry
Fri Mar 01 00:00:00 EST 2013
Cytometric profiling in various clinical forms of multiple sclerosis with respect to CD21+, CD32+, and CD35+ B and T cells.
Translational neurodegeneration
Zandieh A,Izad M,Fakhri M,Amirifard H,Khazaeipour Z,Harirchian MH
15-0081 was used in Flow cytometry/Cell sorting to evaluate the frequency of various immune cell subsets expressing certain CD cell surface markers in MS clinical courses.
Tue Jul 02 00:00:00 EDT 2013
TGFβ1 overexpression by keratinocytes alters skin dendritic cell homeostasis and enhances contact hypersensitivity.
The Journal of investigative dermatology
Mohammed J,Gunderson AJ,Khong HH,Koubek RD,Udey MC,Glick AB
15-0081 was used in Flow cytometry/Cell sorting to highlight a role for keratinocyte-derived TGFβ1 in dendritic cell trafficking and in the initiation of skin inflammation.
Tue Jan 01 00:00:00 EST 2013
A mouse model for inducible overexpression of Prdm14 results in rapid-onset and highly penetrant T-cell acute lymphoblastic leukemia (T-ALL).
Disease models & mechanisms
Carofino BL,Ayanga B,Justice MJ
Published figure using CD8a monoclonal antibody (Product # 15-0081-82) in Flow Cytometry
Fri Nov 01 00:00:00 EDT 2013
Coactivator-associated arginine methyltransferase 1 regulates fetal hematopoiesis and thymocyte development.
Journal of immunology (Baltimore, Md. : 1950)
Li J,Zhao Z,Carter C,Ehrlich LI,Bedford MT,Richie ER
15-0081 was used in Flow cytometry/Cell sorting to demonstrate how CARM1 is a key epigenetic regulator of hematopoiesis that affects multiple lineages at various stages of differentiation.
Tue Jan 15 00:00:00 EST 2013
Antitumor activity of tumor-targeted RNA replicase-based plasmid that expresses interleukin-2 in a murine melanoma model.
Molecular pharmaceutics
Rodriguez BL,Blando JM,Lansakara-P DS,Kiguchi Y,DiGiovanni J,Cui Z
15-0081 was used in Flow cytometry/Cell sorting to evaluate the possible augmentation of pSIN-β function by incorporating the cytokine IL2.
Mon Jun 03 00:00:00 EDT 2013
Interleukin-22 as a molecular adjuvant facilitates IL-17-producing CD8+ T cell responses against a HBV DNA vaccine in mice.
Human vaccines & immunotherapeutics
Wu B,Zou Q,Hu Y,Wang B
Published figure using CD8a monoclonal antibody (Product # 15-0081-82) in Flow Cytometry
Tue Oct 01 00:00:00 EDT 2013
TDP2-dependent non-homologous end-joining protects against topoisomerase II-induced DNA breaks and genome instability in cells and in vivo.
PLoS genetics
Gómez-Herreros F,Romero-Granados R,Zeng Z,Alvarez-Quilón A,Quintero C,Ju L,Umans L,Vermeire L,Huylebroeck D,Caldecott KW,Cortés-Ledesma F
Published figure using CD8a monoclonal antibody (Product # 15-0081-82) in Flow Cytometry
Thu Jun 13 00:00:00 EDT 2013
CD4⁺ but not CD8⁺ T cells revert the impaired emotional behavior of immunocompromised RAG-1-deficient mice.
Translational psychiatry
Rattazzi L,Piras G,Ono M,Deacon R,Pariante CM,D'Acquisto F
15-0081 was used in Flow cytometry/Cell sorting to understand the mechanisms linking an immunocompromised state to a variety of mood disorders.
Tue Jul 09 00:00:00 EDT 2013
In vivo CD8+ T cell dynamics in the liver of Plasmodium yoelii immunized and infected mice.
PloS one
Cabrera M,Pewe LL,Harty JT,Frevert U
Published figure using CD8a monoclonal antibody (Product # 15-0081-82) in Flow Cytometry
Tue Mar 18 00:00:00 EDT 2014
A missing PD-L1/PD-1 coinhibition regulates diabetes induction by preproinsulin-specific CD8 T-cells in an epitope-specific manner.
PloS one
Schuster C,Brosi H,Stifter K,Boehm BO,Schirmbeck R
Published figure using CD8a monoclonal antibody (Product # 15-0081-82) in Flow Cytometry
Tue Apr 08 00:00:00 EDT 2014
Partial depletion of regulatory T cells does not influence the inflammation caused by high dose hemi-body irradiation.
PloS one
Ma S,Richardson JA,Bitmansour A,Solberg TD,Pidikiti R,Song K,Stojadinovic S,Vitetta ES,Meyer JJ
15-0081 was used in Flow cytometry/Cell sorting to investigate the effects of partial depletion of regulatory T cells alongside ionizing radiation on inflammation and tissue injury in mice.
Mon Jul 29 00:00:00 EDT 2013
Absence of Wip1 partially rescues Atm deficiency phenotypes in mice.
Oncogene
Darlington Y,Nguyen TA,Moon SH,Herron A,Rao P,Zhu C,Lu X,Donehower LA
Published figure using CD8a monoclonal antibody (Product # 15-0081-82) in Flow Cytometry
Thu Mar 01 00:00:00 EST 2012
Myeloid-specific tristetraprolin deficiency in mice results in extreme lipopolysaccharide sensitivity in an otherwise minimal phenotype.
Journal of immunology (Baltimore, Md. : 1950)
Qiu LQ,Stumpo DJ,Blackshear PJ
15-0081 was used in Flow cytometry/Cell sorting to show that myeloid-specific TTP deficiency does not phenocopy complete TTP deficiency in C57BL/6 mice.
Tue May 15 00:00:00 EDT 2012
Evaluation of Lassa virus vaccine immunogenicity in a CBA/J-ML29 mouse model.
Vaccine
Goicochea MA,Zapata JC,Bryant J,Davis H,Salvato MS,Lukashevich IS
Published figure using CD8a monoclonal antibody (Product # 15-0081-82) in Flow Cytometry
Tue Feb 14 00:00:00 EST 2012
Characterization of transgenic mice expressing cancer-associated variants of human NOTCH1.
Genesis (New York, N.Y. : 2000)
Berquam-Vrieze KE,Swing DA,Tessarollo L,Dupuy AJ
Published figure using CD8a monoclonal antibody (Product # 15-0081-82) in Flow Cytometry
Wed Feb 01 00:00:00 EST 2012
Sensitized phenotypic screening identifies gene dosage sensitive region on chromosome 11 that predisposes to disease in mice.
EMBO molecular medicine
Ermakova O,Piszczek L,Luciani L,Cavalli FM,Ferreira T,Farley D,Rizzo S,Paolicelli RC,Al-Banchaabouchi M,Nerlov C,Moriggl R,Luscombe NM,Gross C
Published figure using CD8a monoclonal antibody (Product # 15-0081-82) in Flow Cytometry
Sat Jan 01 00:00:00 EST 2011
T cell factor 1 regulates thymocyte survival via a RORγt-dependent pathway.
Journal of immunology (Baltimore, Md. : 1950)
Wang R,Xie H,Huang Z,Ma J,Fang X,Ding Y,Sun Z
Published figure using CD8a monoclonal antibody (Product # 15-0081-82) in Flow Cytometry
Thu Dec 01 00:00:00 EST 2011
An information theoretic, microfluidic-based single cell analysis permits identification of subpopulations among putatively homogeneous stem cells.
PloS one
Glotzbach JP,Januszyk M,Vial IN,Wong VW,Gelbard A,Kalisky T,Thangarajah H,Longaker MT,Quake SR,Chu G,Gurtner GC
15-0081 was used in Flow cytometry/Cell sorting to develop a novel method to characterize and predict transcriptional programs across individual homogeneous stem cells.
Wed Nov 02 00:00:00 EDT 2011
A role for IL-27p28 as an antagonist of gp130-mediated signaling.
Nature immunology
Stumhofer JS,Tait ED,Quinn WJ,Hosken N,Spudy B,Goenka R,Fielding CA,O'Hara AC,Chen Y,Jones ML,Saris CJ,Rose-John S,Cua DJ,Jones SA,Elloso MM,Grötzinger J,Cancro MP,Levin SD,Hunter CA
15-0081 was used in in vitro experiments to indicate a role for IL-27p28 as an antagonist of gp130-mediated signaling.
Wed Dec 01 00:00:00 EST 2010
Plasmacytoid and conventional dendritic cells are early producers of IL-12 in Neospora caninum-infected mice.
Immunology and cell biology
Teixeira L,Botelho AS,Mesquita SD,Correia A,Cerca F,Costa R,Sampaio P,Castro AG,Vilanova M
15-0081 was used in Flow cytometry/Cell sorting to investiagte the maturation and activation of splenic conventional and plasmacytoid dendritic cells in Neospora caninum-infected mice.
Fri Jan 01 00:00:00 EST 2010
Dendritic cells engineered to secrete anti-GITR antibodies are effective adjuvants to dendritic cell-based immunotherapy.
Cancer gene therapy
Boczkowski D,Lee J,Pruitt S,Nair S
15-0081 was used in Flow cytometry/Cell sorting to show significantly enhanced tumor immunity through vaccination with a combination of anti-GITR-secreting dendritic cells and tumor antigen-presenting dendritic cells, providing an effective tumor vaccine adjuvant.
Tue Dec 01 00:00:00 EST 2009
Dynamic imaging of T cell-parasite interactions in the brains of mice chronically infected with Toxoplasma gondii.
Journal of immunology (Baltimore, Md. : 1950)
Schaeffer M,Han SJ,Chtanova T,van Dooren GG,Herzmark P,Chen Y,Roysam B,Striepen B,Robey EA
15-0081 was used in Flow cytometry/Cell sorting to directly observe the dynamics of T cell-parasite interactions within living tissue and further understand immune responses to persistent pathogens in the brain.
Fri May 15 00:00:00 EDT 2009
4-1BB functions as a survival factor in dendritic cells.
Journal of immunology (Baltimore, Md. : 1950)
Choi BK,Kim YH,Kwon PM,Lee SC,Kang SW,Kim MS,Lee MJ,Kwon BS
15-0081 was used in Flow cytometry/Cell sorting to investigate the function of CD137 on dendritic cells, showing that it functions as a survival factor.
Wed Apr 01 00:00:00 EDT 2009
Investigation of the impact of the common animal facility contaminant murine norovirus on experimental murine cytomegalovirus infection.
Virology
Doom CM,Turula HM,Hill AB
15-0081 was used in Flow cytometry/Cell sorting to investigate that while MNV-1 has a mild impact on the immune response to MCMV, it is not likely to affect most experimental outcomes in immunocompetent mice in the MCMV model.
Wed Sep 30 00:00:00 EDT 2009
Targeting of antigens to B cells augments antigen-specific T-cell responses and breaks immune tolerance to tumor-associated antigen MUC1.
Blood
Ding C,Wang L,Marroquin J,Yan J
15-0081 was used in Flow cytometry/Cell sorting to reveal that ovalbumin targeted to B cells via CD19 stimulates augmented CD4 and CD8 T-cell proliferation and expansion.
Wed Oct 01 00:00:00 EDT 2008
CXCL9, but not CXCL10, promotes CXCR3-dependent immune-mediated kidney disease.
Journal of the American Society of Nephrology : JASN
Menke J,Zeller GC,Kikawada E,Means TK,Huang XR,Lan HY,Lu B,Farber J,Luster AD,Kelley VR
15-0081 was used in Immunohistochemistry to identify additional therapeutic chemokine targets for immune-mediated nephritis.
Sun Jun 01 00:00:00 EDT 2008
Rapid accumulation of adoptively transferred CD8+ T cells at the tumor site is associated with long-term control of SV40 T antigen-induced tumors.
Cancer immunology, immunotherapy : CII
Yorty JL,Tevethia SS,Schell TD
15-0081 was used in Flow cytometry/Cell sorting to show that greater control of established autochthonous tumours is associated with the early accumulation of adoptively transferred T cells.
Sun Jun 01 00:00:00 EDT 2008
Synergistic antitumor effects of CpG oligodeoxynucleotide and STAT3 inhibitory agent JSI-124 in a mouse melanoma tumor model.
Immunology and cell biology
Molavi O,Ma Z,Hamdy S,Lai R,Lavasanifar A,Samuel J
15-0081 was used in Flow cytometry/Cell sorting to provide the proof-of-principle for combining CpG and JSI-124 to enhance anti-tumour immune responses.
Mon Oct 20 00:00:00 EDT 2008
Sunlight triggers cutaneous lupus through a CSF-1-dependent mechanism in MRL-Fas(lpr) mice.
Journal of immunology (Baltimore, Md. : 1950)
Menke J,Hsu MY,Byrne KT,Lucas JA,Rabacal WA,Croker BP,Zong XH,Stanley ER,Kelley VR
15-0081 was used in Flow cytometry/Cell sorting to investigate the role of UVB in cutaneous lupus erythematosus, showing that UVB triggers it through a CSF-1-dependent, macrophage-mediated mechanism.
Sat Nov 15 00:00:00 EST 2008
Programmed death ligand 1 regulates a critical checkpoint for autoimmune myocarditis and pneumonitis in MRL mice.
Journal of immunology (Baltimore, Md. : 1950)
Lucas JA,Menke J,Rabacal WA,Schoen FJ,Sharpe AH,Kelley VR
15-0081 was used in Flow cytometry/Cell sorting to compare kidney and systemic illness in PD-L1 null and PD-L1 intact mouse models of lupus.
Fri Aug 15 00:00:00 EDT 2008
Pervasive and stochastic changes in the TCR repertoire of regulatory T-cell-deficient mice.
International immunology
Zheng L,Sharma R,Kung JT,Deshmukh US,Jarjour WN,Fu SM,Ju ST
15-0081 was used in Flow cytometry/Cell sorting to compare the T-cell receptor V beta gene family expression profile of normal and Treg-lacking mice.
Tue Apr 01 00:00:00 EDT 2008
Suppression of alkali burn-induced corneal neovascularization by dendritic cell vaccination targeting VEGF receptor 2.
Investigative ophthalmology & visual science
Mochimaru H,Usui T,Yaguchi T,Nagahama Y,Hasegawa G,Usui Y,Shimmura S,Tsubota K,Amano S,Kawakami Y,Ishida S
Thu May 01 00:00:00 EDT 2008
Combined anti-CD40 conditioning and well-timed immunization prolongs CD8+ T cell accumulation and control of established brain tumors.
Journal of immunotherapy (Hagerstown, Md. : 1997)
Ryan CM,Staveley-O'Carroll K,Schell TD
15-0081 was used in Flow cytometry/Cell sorting to investigate the augmentation of CD8+ T-cell-mediated adoptive immunotherapy by targeting a weakly immunogenic epitope.
Mon Jul 13 00:00:00 EDT 2009
The impact of altered p53 dosage on hematopoietic stem cell dynamics during aging.
Blood
Dumble M,Moore L,Chambers SM,Geiger H,Van Zant G,Goodell MA,Donehower LA
15-0081 was used in Flow cytometry/Cell sorting to study how altering p53 dosage during ageing impacts hematopoietic stem cell dynamics.
Thu Feb 15 00:00:00 EST 2007
DNA immunization using highly conserved murine cytomegalovirus genes encoding homologs of human cytomegalovirus UL54 (DNA polymerase) and UL105 (helicase) elicits strong CD8 T-cell responses and is protective against systemic challenge.
Journal of virology
Morello CS,Kelley LA,Munks MW,Hill AB,Spector DH
15-0081 was used in Flow cytometry/Cell sorting to investigate essential CMV proteins as a novel class of T-cell targets for vaccine-mediated protection.
Sun Jul 01 00:00:00 EDT 2007
Myocardial infarct-sparing effect of adenosine A2A receptor activation is due to its action on CD4+ T lymphocytes.
Circulation
Yang Z,Day YJ,Toufektsian MC,Xu Y,Ramos SI,Marshall MA,French BA,Linden J
Tue Nov 07 00:00:00 EST 2006
Developmental switch of mouse hematopoietic stem cells from fetal to adult type occurs in bone marrow after birth.
Proceedings of the National Academy of Sciences of the United States of America
Kikuchi K,Kondo M
15-0081 was used in Flow cytometry/Cell sorting to demonstrate how foetal haematopoietic stem cells may acquire adult characteristics between 1 and 2 weeks after birth in mouse bone marrow.
Tue Nov 21 00:00:00 EST 2006
