Product References
Toll-like receptor mediated inflammation directs B cells towards protective antiviral extrafollicular responses.
Nature communications
Lam JH,Baumgarth N
56-0081-82 was used in Flow cytometry/Cell sorting to show that influenza infection rapidly induces EFRs, generating protective antibodies via Toll-like receptor (TLR)-mediated mechanisms that are both B cell intrinsic and extrinsic.
Wed Jul 05 00:00:00 EDT 2023
Hobit and Blimp-1 regulate TRM abundance after LCMV infection by suppressing tissue exit pathways of TRM precursors.
European journal of immunology
Parga-Vidal L,Taggenbrock RLRE,Beumer-Chuwonpad A,Aglmous H,Kragten NAM,Behr FM,Bovens AA,van Lier RAW,Stark R,van Gisbergen KPJM
56-0081-82 was used in Flow cytometry/Cell sorting to highlight a role of Hobit and Blimp-1 at the branching point of circulating and resident memory lineages by suppressing tissue egress of Trm precursors early during infection.
Fri Jul 01 00:00:00 EDT 2022
Intracellular Acetyl CoA Potentiates the Therapeutic Efficacy of Antitumor CD8+ T Cells.
Cancer research
Chowdhury S,Kar A,Bhowmik D,Gautam A,Basak D,Sarkar I,Ghosh P,Sarkar D,Deka A,Chakraborty P,Mukhopadhyay A,Mehrotra S,Basak S,Paul S,Chatterjee S
56-0081-82 was used in Flow cytometry/Cell sorting to delineate the metabolic configuration of CD8+ T cells required for stable effector function in tumors and present an affordable approach to promote the efficacy of CD8+ T cells for adoptive T-cell therapy.
Mon Jul 18 00:00:00 EDT 2022
Therapeutic potential of highly functional codon-optimized microutrophin for muscle-specific expression.
Scientific reports
Starikova AV,Skopenkova VV,Polikarpova AV,Reshetov DA,Vassilieva SG,Velyaev OA,Shmidt AA,Savchenko IM,Soldatov VO,Egorova TV,Bardina MV
Published figure using CD8a monoclonal antibody (Product # 56-0081-82) in Immunohistochemistry
Mon Jan 17 00:00:00 EST 2022
Neuroinflammation in neuronopathic Gaucher disease: Role of microglia and NK cells, biomarkers, and response to substrate reduction therapy.
eLife
Boddupalli CS,Nair S,Belinsky G,Gans J,Teeple E,Nguyen TH,Mehta S,Guo L,Kramer ML,Ruan J,Wang H,Davison M,Kumar D,Vidyadhara DJ,Zhang B,Klinger K,Mistry PK
56-0081-82 was used in Flow cytometry/Cell sorting to advance nGD disease biology whilst identifying compelling biomarkers of nGD to improve patient management, enrich clinical trials, and illuminate therapeutic targets.
Tue Aug 16 00:00:00 EDT 2022
SYK coordinates neuroprotective microglial responses in neurodegenerative disease.
Cell
Ennerfelt H,Frost EL,Shapiro DA,Holliday C,Zengeler KE,Voithofer G,Bolte AC,Lammert CR,Kulas JA,Ulland TK,Lukens JR
56-0081-82 was used in flow cytometry to study the critical intracellular molecules that orchestrate neuroprotective functions of microglia.
Thu Oct 27 00:00:00 EDT 2022
Dysbiosis exacerbates colitis by promoting ubiquitination and accumulation of the innate immune adaptor STING in myeloid cells.
Immunity
Shmuel-Galia L,Humphries F,Lei X,Ceglia S,Wilson R,Jiang Z,Ketelut-Carneiro N,Foley SE,Pechhold S,Houghton J,Muneeruddin K,Shaffer SA,McCormick BA,Reboldi A,Ward D,Marshak-Rothstein A,Fitzgerald KA
56-0081-82 was used in Flow cytometry/Cell sorting to suggest a positive feedback loop wherein dysbiosis foments the accumulation of STING in intestinal myeloid cells, driving intestinal inflammation.
Tue Jun 08 00:00:00 EDT 2021
Chronic T cell proliferation in brains after stroke could interfere with the efficacy of immunotherapies.
The Journal of experimental medicine
Heindl S,Ricci A,Carofiglio O,Zhou Q,Arzberger T,Lenart N,Franzmeier N,Hortobagyi T,Nelson PT,Stowe AM,Denes A,Edbauer D,Liesz A
Published figure using CD8a monoclonal antibody (Product # 56-0081-82) in Flow Cytometry
Mon Aug 02 00:00:00 EDT 2021
A Biological Circuit Involving Mef2c, Mef2d, and Hdac9 Controls the Immunosuppressive Functions of CD4+Foxp3+ T-Regulatory Cells.
Frontiers in immunology
Di Giorgio E,Wang L,Xiong Y,Christensen LM,Akimova T,Han R,Samanta A,Trevisanut M,Brancolini C,Beier UH,Hancock WW
Published figure using CD8a monoclonal antibody (Product # 56-0081-82) in Flow Cytometry
Fri Dec 17 00:00:00 EST 2021
Functional inhibition of lactate dehydrogenase suppresses pancreatic adenocarcinoma progression.
Clinical and translational medicine
Cheng CS,Tan HY,Wang N,Chen L,Meng Z,Chen Z,Feng Y
56-0081-82 was used in Immunohistochemistry to analyze the clinical-pathological characteristics and prognosis of 253 PAAD patients.
Tue Jun 01 00:00:00 EDT 2021
Suppression of mucosal Th17 memory responses by acellular pertussis vaccines enhances nasal Bordetella pertussis carriage.
NPJ vaccines
Dubois V,Chatagnon J,Thiriard A,Bauderlique-Le Roy H,Debrie AS,Coutte L,Locht C
56-0081 was used in Flow cytometry/Cell sorting to show that, unlike wPV, aPV, while protective against lung colonization by Bordetella pertussis (Bp), did not protect BALB/c mice from nasal colonization, but instead substantially prolonged nasal carriage.
Fri Jan 08 00:00:00 EST 2021
Local Sustained GM-CSF Delivery by Genetically Engineered Encapsulated Cells Enhanced Both Cellular and Humoral SARS-CoV-2 Spike-Specific Immune Response in an Experimental Murine Spike DNA Vaccination Model.
Vaccines
Vernet R,Charrier E,Cosset E,Fièvre S,Tomasello U,Grogg J,Mach N
Published figure using CD8a monoclonal antibody (Product # 56-0081-82) in Flow Cytometry
Mon May 10 00:00:00 EDT 2021
Cancer immunotherapy by NC410, a LAIR-2 Fc protein blocking human LAIR-collagen interaction.
eLife
Ramos MIP,Tian L,de Ruiter EJ,Song C,Paucarmayta A,Singh A,Elshof E,Vijver SV,Shaik J,Bosiacki J,Cusumano Z,Jensen C,Willumsen N,Karsdal MA,Liu L,Langermann S,Willems S,Flies D,Meyaard L
Published figure using CD8a monoclonal antibody (Product # 56-0081-82) in Flow Cytometry
Mon Jun 14 00:00:00 EDT 2021
Sensing of endogenous nucleic acids by ZBP1 induces keratinocyte necroptosis and skin inflammation.
The Journal of experimental medicine
Devos M,Tanghe G,Gilbert B,Dierick E,Verheirstraeten M,Nemegeer J,de Reuver R,Lefebvre S,De Munck J,Rehwinkel J,Vandenabeele P,Declercq W,Maelfait J
Published figure using CD8a monoclonal antibody (Product # 56-0081-82) in Flow Cytometry
Mon Jul 06 00:00:00 EDT 2020
Glufosinate constrains synchronous and metachronous metastasis by promoting anti-tumor macrophages.
EMBO molecular medicine
Menga A,Serra M,Todisco S,Riera-Domingo C,Ammarah U,Ehling M,Palmieri EM,Di Noia MA,Gissi R,Favia M,Pierri CL,Porporato PE,Castegna A,Mazzone M
Published figure using CD8a monoclonal antibody (Product # 56-0081-82) in Flow Cytometry
Wed Oct 07 00:00:00 EDT 2020
HDAC Inhibitor, CG-745, Enhances the Anti-Cancer Effect of Anti-PD-1 Immune Checkpoint Inhibitor by Modulation of the Immune Microenvironment.
Journal of Cancer
Kim YD,Park SM,Ha HC,Lee AR,Won H,Cha H,Cho S,Cho JM
Published figure using CD8a monoclonal antibody (Product # 56-0081-82) in Flow Cytometry
Mon Sep 28 00:00:00 EDT 2020
TIAM2S Mediates Serotonin Homeostasis and Provokes a Pro-Inflammatory Immune Microenvironment Permissive for Colorectal Tumorigenesis.
Cancers
Chan YL,Lai WC,Chen JS,Tseng JT,Chuang PC,Jou J,Lee CT,Sun HS
Published figure using CD8a monoclonal antibody (Product # 56-0081-82) in Flow Cytometry
Wed Jul 08 00:00:00 EDT 2020
The lysophospholipase D enzyme Gdpd3 is required to maintain chronic myelogenous leukaemia stem cells.
Nature communications
Naka K,Ochiai R,Matsubara E,Kondo C,Yang KM,Hoshii T,Araki M,Araki K,Sotomaru Y,Sasaki K,Mitani K,Kim DW,Ooshima A,Kim SJ
Published figure using CD8a monoclonal antibody (Product # 56-0081-82) in Flow Cytometry
Thu Sep 17 00:00:00 EDT 2020
RIPK3 and Caspase-1/11 Are Necessary for Optimal Antigen-Specific CD8 T Cell Response Elicited by Genetically Modified Listeria monocytogenes.
Frontiers in immunology
Rana A,de Almeida FC,Paico Montero HA,Gonzales Carazas MM,Bortoluci KR,Sad S,Amarante-Mendes GP
Published figure using CD8a monoclonal antibody (Product # 56-0081-82) in Flow Cytometry
Fri Mar 26 00:00:00 EDT 2021
Artificial Mini Dendritic Cells Boost T Cell-Based Immunotherapy for Ovarian Cancer.
Advanced science (Weinheim, Baden-Wurttemberg, Germany)
Cheng S,Xu C,Jin Y,Li Y,Zhong C,Ma J,Yang J,Zhang N,Li Y,Wang C,Yang Z,Wang Y
Published figure using CD8a monoclonal antibody (Product # 56-0081-82) in Flow Cytometry
Wed Apr 01 00:00:00 EDT 2020
A Cu9S5 nanoparticle-based CpG delivery system for synergistic photothermal-, photodynamic- and immunotherapy.
Communications biology
Zhou L,Chen L,Hu X,Lu Y,Liu W,Sun Y,Yao T,Dong C,Shi S
Published figure using CD8a monoclonal antibody (Product # 56-0081-82) in Immunohistochemistry
Fri Jul 03 00:00:00 EDT 2020
Loss of testosterone impairs anti-tumor neutrophil function.
Nature communications
Markman JL,Porritt RA,Wakita D,Lane ME,Martinon D,Noval Rivas M,Luu M,Posadas EM,Crother TR,Arditi M
Published figure using CD8a monoclonal antibody (Product # 56-0081-82) in Flow Cytometry
Tue Mar 31 00:00:00 EDT 2020
Bisphosphoglycerate Mutase Deficiency Protects against Cerebral Malaria and Severe Malaria-Induced Anemia.
Cell reports
Xu G,van Bruggen R,Gualtieri CO,Moradin N,Fois A,Vallerand D,De Sa Tavares Russo M,Bassenden A,Lu W,Tam M,Lesage S,Girouard H,Avizonis DZ,Deblois G,Prchal JT,Stevenson M,Berghuis A,Muir T,Rabinowitz J,Vidal SM,Fodil N,Gros P
56-0081 was used in Flow cytometry/Cell sorting to highlight the importance of BPGM as a regulator of hemoglobin/oxyhemoglobin in malaria pathogenesis and suggest a new potential malaria therapeutic target.
Tue Sep 22 00:00:00 EDT 2020
Nuclear imaging-guided PD-L1 blockade therapy increases effectiveness of cancer immunotherapy.
Journal for immunotherapy of cancer
Gao H,Wu Y,Shi J,Zhang X,Liu T,Hu B,Jia B,Wan Y,Liu Z,Wang F
Published figure using CD8a monoclonal antibody (Product # 56-0081-82) in Flow Cytometry
Sun Nov 01 00:00:00 EDT 2020
Gasdermin D in macrophages restrains colitis by controlling cGAS-mediated inflammation.
Science advances
Ma C,Yang D,Wang B,Wu C,Wu Y,Li S,Liu X,Lassen K,Dai L,Yang S
Published figure using CD8a monoclonal antibody (Product # 56-0081-82) in Flow Cytometry
Fri May 01 00:00:00 EDT 2020
Requirements for the differentiation of innate T-bethigh memory-phenotype CD4+ T lymphocytes under steady state.
Nature communications
Kawabe T,Yi J,Kawajiri A,Hilligan K,Fang D,Ishii N,Yamane H,Zhu J,Jankovic D,Kim KS,Trinchieri G,Sher A
56-0081 was used in Flow cytometry/Cell sorting to study whether MP CD4+ T cells are functionally heterogeneous and, if so, what signals specify the differentiation of MP cell subpopulations under homeostatic conditions.
Mon Jul 06 00:00:00 EDT 2020
ICOS agonism by JTX-2011 (vopratelimab) requires initial T cell priming and Fc cross-linking for optimal T cell activation and anti-tumor immunity in preclinical models.
PloS one
Hanson A,Elpek K,Duong E,Shallberg L,Fan M,Johnson C,Wallace M,Mabry GR,Sazinsky S,Pepper L,Shu CJ,Sathyanarayanan S,Zuerndorfer S,Simpson T,Gostissa M,Briskin M,Law D,Michaelson J,Harvey CJ
Published figure using CD8a monoclonal antibody (Product # 56-0081-82) in Flow Cytometry
Mon Nov 16 00:00:00 EST 2020
Mucosal-associated invariant T cells promote inflammation and intestinal dysbiosis leading to metabolic dysfunction during obesity.
Nature communications
Toubal A,Kiaf B,Beaudoin L,Cagninacci L,Rhimi M,Fruchet B,da Silva J,Corbett AJ,Simoni Y,Lantz O,Rossjohn J,McCluskey J,Lesnik P,Maguin E,Lehuen A
56-0081 was used in Flow cytometry/Cell sorting to show that during obesity MAIT cells promote inflammation in both adipose tissue and ileum, leading to insulin resistance and impaired glucose and lipid metabolism.
Fri Jul 24 00:00:00 EDT 2020
Specific targeting of IL-1β activity to CD8+ T cells allows for safe use as a vaccine adjuvant.
NPJ vaccines
Van Den Eeckhout B,Van Hoecke L,Burg E,Van Lint S,Peelman F,Kley N,Uzé G,Saelens X,Tavernier J,Gerlo S
Published figure using CD8a monoclonal antibody (Product # 56-0081-82) in Flow Cytometry
Tue Sep 19 00:00:00 EDT 2023
Compartmentalized gut lymph node drainage dictates adaptive immune responses.
Nature
Esterházy D,Canesso MCC,Mesin L,Muller PA,de Castro TBR,Lockhart A,ElJalby M,Faria AMC,Mucida D
56-0081-82 was used in Flow Cytometry to show drainage of gut-draining lymph nodes can resolve conflicting tolerogenic and inflammatory intestinal responses by encouraging antigen targeting to specific gut segments.
Wed May 01 00:00:00 EDT 2019
CD8+ T cells induce cachexia during chronic viral infection.
Nature immunology
Baazim H,Schweiger M,Moschinger M,Xu H,Scherer T,Popa A,Gallage S,Ali A,Khamina K,Kosack L,Vilagos B,Smyth M,Lercher A,Friske J,Merkler D,Aderem A,Helbich TH,Heikenwälder M,Lang PA,Zechner R,Bergthaler A
56-0081-82 was used in Flow Cytometry to identify the role for CD8+ T cells in infection-associated cachexia.
Sat Jun 01 00:00:00 EDT 2019
Lineage-specific events underlie aortic root aneurysm pathogenesis in Loeys-Dietz syndrome.
The Journal of clinical investigation
MacFarlane EG,Parker SJ,Shin JY,Kang BE,Ziegler SG,Creamer TJ,Bagirzadeh R,Bedja D,Chen Y,Calderon JF,Weissler K,Frischmeyer-Guerrerio PA,Lindsay ME,Habashi JP,Dietz HC
56-0081 was used in Flow cytometry/Cell sorting to highlight the importance of considering the regional microenvironment and specifically lineage-dependent variation in the vulnerability to mutations in the developmnet and testing of pathogenic models for aortic aneurysm.
Fri Feb 01 00:00:00 EST 2019
Antiallodynic Effects of Cannabinoid Receptor 2 (CB2R) Agonists on Retrovirus Infection-Induced Neuropathic Pain.
Pain research & management
Sheng WS,Chauhan P,Hu S,Prasad S,Lokensgard JR
Published figure using CD8a monoclonal antibody (Product # 56-0081-82) in Flow Cytometry
Mon Dec 16 00:00:00 EST 2019
A functional subset of CD8+ T cells during chronic exhaustion is defined by SIRPα expression.
Nature communications
Myers LM,Tal MC,Torrez Dulgeroff LB,Carmody AB,Messer RJ,Gulati G,Yiu YY,Staron MM,Angel CL,Sinha R,Markovic M,Pham EA,Fram B,Ahmed A,Newman AM,Glenn JS,Davis MM,Kaech SM,Weissman IL,Hasenkrug KJ
56-0081-82 was used in Flow Cytometry to demonstrate that even during exhaustion there is a subset of functional CD8+ T cells defined by surface expression of SIRPα.
Fri Feb 15 00:00:00 EST 2019
Sialic Acid Blockade Suppresses Tumor Growth by Enhancing T-cell-Mediated Tumor Immunity.
Cancer research
Büll C,Boltje TJ,Balneger N,Weischer SM,Wassink M,van Gemst JJ,Bloemendal VR,Boon L,van der Vlag J,Heise T,den Brok MH,Adema GJ
56-0081 was used in Flow cytometry/Cell sorting to show that sialic acid sugars function as important modulators of the immunosuppressive tumor microenvironment that limit potent antitumor immunity.
Sun Jul 01 00:00:00 EDT 2018
Complement Activation via a C3a Receptor Pathway Alters CD4+ T Lymphocytes and Mediates Lung Cancer Progression.
Cancer research
Kwak JW,Laskowski J,Li HY,McSharry MV,Sippel TR,Bullock BL,Johnson AM,Poczobutt JM,Neuwelt AJ,Malkoski SP,Weiser-Evans MC,Lambris JD,Clambey ET,Thurman JM,Nemenoff RA
56-0081 was used in Flow cytometry/Cell sorting to study the mechanism relating complement activation to tumour progression in multiple immunocompetent orthotopic models of lung cancer.
Mon Jan 01 00:00:00 EST 2018
Langerin+ CD8α+ Dendritic Cells Drive Early CD8+ T Cell Activation and IL-12 Production During Systemic Bacterial Infection.
Frontiers in immunology
Prendergast KA,Daniels NJ,Petersen TR,Hermans IF,Kirman JR
56-0081 was used in Flow cytometry/Cell sorting to investigate the impact of depleting langerin+ CD8α+ dendritic cells in a murine model of intravenous infection with Mycobacterium bovis bacille Calmette-Guerin.
Mon Jul 01 00:00:00 EDT 2019
Inducible Costimulator Expressing T Cells Promote Parasitic Growth During Blood Stage Plasmodium berghei ANKA Infection.
Frontiers in immunology
Jogdand GM,Sengupta S,Bhattacharya G,Singh SK,Barik PK,Devadas S
56-0081 was used in Flow cytometry/Cell sorting to study the role of inducible costimulator in lethal blood-stage of Plasmodium berghei ANKA infection.
Thu Jul 11 00:00:00 EDT 2019
STAT1 is a sex-specific tumor suppressor in colitis-associated colorectal cancer.
Molecular oncology
Crnčec I,Modak M,Gordziel C,Svinka J,Scharf I,Moritsch S,Pathria P,Schlederer M,Kenner L,Timelthaler G,Müller M,Strobl B,Casanova E,Bayer E,Mohr T,Stöckl J,Friedrich K,Eferl R
Published figure using CD8a monoclonal antibody (Product # 56-0081-82) in Flow Cytometry
Sun Apr 01 00:00:00 EDT 2018
Inhibiting TrxR suppresses liver cancer by inducing apoptosis and eliciting potent antitumor immunity.
Oncology reports
Lei H,Wang G,Zhang J,Han Q
Published figure using CD8a monoclonal antibody (Product # 56-0081-82) in Flow Cytometry
Sat Dec 01 00:00:00 EST 2018
Sipa1 deficiency unleashes a host-immune mechanism eradicating chronic myelogenous leukemia-initiating cells.
Nature communications
Xu Y,Ikeda S,Sumida K,Yamamoto R,Tanaka H,Minato N
Published figure using CD8a monoclonal antibody (Product # 56-0081-82) in Flow Cytometry
Fri Mar 02 00:00:00 EST 2018
Oncofetal gene SALL4 reactivation by hepatitis B virus counteracts miR-200c in PD-L1-induced T cell exhaustion.
Nature communications
Sun C,Lan P,Han Q,Huang M,Zhang Z,Xu G,Song J,Wang J,Wei H,Zhang J,Sun R,Zhang C,Tian Z
Published figure using CD8a monoclonal antibody (Product # 56-0081-82) in Immunofluorescence
Wed Mar 28 00:00:00 EDT 2018
Type 2 Innate Lymphocytes Actuate Immunity Against Tumours and Limit Cancer Metastasis.
Scientific reports
Saranchova I,Han J,Zaman R,Arora H,Huang H,Fenninger F,Choi KB,Munro L,Pfeifer CG,Welch I,Takei F,Jefferies WA
Published figure using CD8a monoclonal antibody (Product # 56-0081-82) in Immunohistochemistry
Tue Feb 13 00:00:00 EST 2018
A stochastic epigenetic switch controls the dynamics of T-cell lineage commitment.
eLife
Ng KK,Yui MA,Mehta A,Siu S,Irwin B,Pease S,Hirose S,Elowitz MB,Rothenberg EV,Kueh HY
Published figure using CD8a monoclonal antibody (Product # 56-0081-82) in Flow Cytometry
Tue Nov 20 00:00:00 EST 2018
Differential requirement of kindlin-3 for T cell progenitor homing to the non-vascularized and vascularized thymus.
eLife
Moretti FA,Klapproth S,Ruppert R,Margraf A,Weber J,Pick R,Scheiermann C,Sperandio M,Fässler R,Moser M
Published figure using CD8a monoclonal antibody (Product # 56-0081-82) in Flow Cytometry
Thu Sep 06 00:00:00 EDT 2018
A protocol for generating induced T cells by reprogramming B cells in vivo.
Cell regeneration (London, England)
Weng Q,Hu F,Zhang M,Dong Y,Lv C,Wang Y,Liu X,Wang J
Published figure using CD8a monoclonal antibody (Product # 56-0081-82) in Flow Cytometry
Sat Sep 01 00:00:00 EDT 2018
Macrophage Depletion Protects against Cigarette Smoke-Induced Inflammatory Response in the Mouse Colon and Lung.
Frontiers in physiology
Lim D,Kim W,Lee C,Bae H,Kim J
Published figure using CD8a monoclonal antibody (Product # 56-0081-82) in Flow Cytometry
Wed Sep 30 00:00:00 EDT 2020
Loss of Nucleobindin-2 Causes Insulin Resistance in Obesity without Impacting Satiety or Adiposity.
Cell reports
Ravussin A,Youm YH,Sander J,Ryu S,Nguyen K,Varela L,Shulman GI,Sidorov S,Horvath TL,Schultze JL,Dixit VD
Published figure using CD8a monoclonal antibody (Product # 56-0081-82) in Flow Cytometry
Tue Jul 31 00:00:00 EDT 2018
Modifying the cancer-immune set point using vaccinia virus expressing re-designed interleukin-2.
Nature communications
Liu Z,Ge Y,Wang H,Ma C,Feist M,Ju S,Guo ZS,Bartlett DL
Published figure using CD8a monoclonal antibody (Product # 56-0081-82) in Flow Cytometry
Thu Nov 08 00:00:00 EST 2018
Microbiota Reconstitution Does Not Cause Bone Loss in Germ-Free Mice.
mSphere
Quach D,Collins F,Parameswaran N,McCabe L,Britton RA
Published figure using CD8a monoclonal antibody (Product # 56-0081-82) in Flow Cytometry
Wed Nov 20 00:00:00 EST 2019
PDL2+ CD11b+ dermal dendritic cells capture topical antigen through hair follicles to prime LAP+ Tregs.
Nature communications
Tordesillas L,Lozano-Ojalvo D,Dunkin D,Mondoulet L,Agudo J,Merad M,Sampson HA,Berin MC
56-0081 was used in Flow cytometry/Cell sorting to show how topical antigen is acquired and presented by dendritic cells in the skin.
Fri Dec 07 00:00:00 EST 2018
Estriol Reduces Pulmonary Immune Cell Recruitment and Inflammation to Protect Female Mice From Severe Influenza.
Endocrinology
Vermillion MS,Ursin RL,Attreed SE,Klein SL
56-0081-82 was used in Flow cytometry/Cell sorting to suggest that exogenous E3 confers protection during IAV infection through immunomodulatory mechanisms and that E3 may have broad therapeutic potential in the context of both infectious and noninfectious inflammatory diseases.
Sat Sep 01 00:00:00 EDT 2018
Intestinal Epithelial and Intraepithelial T Cell Crosstalk Mediates a Dynamic Response to Infection.
Cell
Hoytema van Konijnenburg DP,Reis BS,Pedicord VA,Farache J,Victora GD,Mucida D
56-0081 was used in Flow cytometry/Cell sorting to investigate the nature of intestinal intraepithelial lymphocyte responses to luminal microbes.
Thu Nov 02 00:00:00 EDT 2017
Adipose tissue B2 cells promote insulin resistance through leukotriene LTB4/LTB4R1 signaling.
The Journal of clinical investigation
Ying W,Wollam J,Ofrecio JM,Bandyopadhyay G,El Ouarrat D,Lee YS,Oh DY,Li P,Osborn O,Olefsky JM
Published figure using CD8a monoclonal antibody (Product # 56-0081-82) in Flow Cytometry
Wed Mar 01 00:00:00 EST 2017
Combined antiangiogenic and anti-PD-L1 therapy stimulates tumor immunity through HEV formation.
Science translational medicine
Allen E,Jabouille A,Rivera LB,Lodewijckx I,Missiaen R,Steri V,Feyen K,Tawney J,Hanahan D,Michael IP,Bergers G
Published figure using CD8a monoclonal antibody (Product # 56-0081-82) in Flow Cytometry
Wed Apr 12 00:00:00 EDT 2017
Egr2 and 3 control adaptive immune responses by temporally uncoupling expansion from T cell differentiation.
The Journal of experimental medicine
Miao T,Symonds ALJ,Singh R,Symonds JD,Ogbe A,Omodho B,Zhu B,Li S,Wang P
Published figure using CD8a monoclonal antibody (Product # 56-0081-82) in Flow Cytometry
Mon Jun 05 00:00:00 EDT 2017
A New Adjuvant MTOM Mediates Mycobacterium tuberculosis Subunit Vaccine to Enhance Th1-Type T Cell Immune Responses and IL-2+ T Cells.
Frontiers in immunology
Yu Q,Wang X,Fan X
Published figure using CD8a monoclonal antibody (Product # 56-0081-82) in Flow Cytometry
Wed Nov 20 00:00:00 EST 2019
Betulin from Hedyotis hedyotidea ameliorates concanavalin A-induced and T cell-mediated autoimmune hepatitis in mice.
Acta pharmacologica Sinica
Zhou YQ,Weng XF,Dou R,Tan XS,Zhang TT,Fang JB,Wu XW
Published figure using CD8a monoclonal antibody (Product # 56-0081-82) in Flow Cytometry
Wed Feb 01 00:00:00 EST 2017
Differential Inhibitory Receptor Expression on T Cells Delineates Functional Capacities in Chronic Viral Infection.
Journal of virology
Teigler JE,Zelinskyy G,Eller MA,Bolton DL,Marovich M,Gordon AD,Alrubayyi A,Alter G,Robb ML,Martin JN,Deeks SG,Michael NL,Dittmer U,Streeck H
56-0081 was used in Flow cytometry/Cell sorting to determine and compare inhibitory receptor expression patterns on virus-specific CD4 and CD8 T cells in relation to their functional T cell profile.
Fri Dec 01 00:00:00 EST 2017
Role of Triggering Receptor Expressed on Myeloid Cell-1 Expression in Mammalian Target of Rapamycin Modulation of CD8+ T-cell Differentiation during the Immune Response to Invasive Pulmonary Aspergillosis.
Chinese medical journal
Cui N,Wang H,Su LX,Zhang JH,Long Y,Liu DW
Published figure using CD8a monoclonal antibody (Product # 56-0081-82) in Flow Cytometry
Sat May 20 00:00:00 EDT 2017
Immunological phenotype of the murine Lrba knockout.
Immunology and cell biology
Gámez-Díaz L,Neumann J,Jäger F,Proietti M,Felber F,Soulas-Sprauel P,Perruzza L,Grassi F,Kögl T,Aichele P,Kilimann M,Grimbacher B,Jung S
Published figure using CD8a monoclonal antibody (Product # 56-0081-82) in Flow Cytometry
Sun Oct 01 00:00:00 EDT 2017
The inflammatory phase of fracture healing is influenced by oestrogen status in mice.
European journal of medical research
Haffner-Luntzer M,Fischer V,Prystaz K,Liedert A,Ignatius A
Published figure using CD8a monoclonal antibody (Product # 56-0081-82) in Immunofluorescence
Thu Jul 06 00:00:00 EDT 2017
ADAR1 deletion induces NFκB and interferon signaling dependent liver inflammation and fibrosis.
RNA biology
Ben-Shoshan SO,Kagan P,Sultan M,Barabash Z,Dor C,Jacob-Hirsch J,Harmelin A,Pappo O,Marcu-Malina V,Ben-Ari Z,Amariglio N,Rechavi G,Goldstein I,Safran M
Published figure using CD8a monoclonal antibody (Product # 56-0081-82) in Flow Cytometry
Thu May 04 00:00:00 EDT 2017
IL-2/Anti-IL-2 Complex Attenuates Inflammation and BBB Disruption in Mice Subjected to Traumatic Brain Injury.
Frontiers in neurology
Gao W,Li F,Zhou Z,Xu X,Wu Y,Zhou S,Yin D,Sun D,Xiong J,Jiang R,Zhang J
Published figure using CD8a monoclonal antibody (Product # 56-0081-82) in Flow Cytometry
Thu Oct 01 00:00:00 EDT 2020
Calreticulin is an effective immunologic adjuvant to tumor-associated antigens.
Experimental and therapeutic medicine
Wang J,Gao ZP,Qin S,Liu CB,Zou LL
Published figure using CD8a monoclonal antibody (Product # 56-0081-82) in Flow Cytometry
Sun Oct 01 00:00:00 EDT 2017
Transient Treg depletion enhances therapeutic anti-cancer vaccination.
Immunity, inflammation and disease
Fisher SA,Aston WJ,Chee J,Khong A,Cleaver AL,Solin JN,Ma S,Lesterhuis WJ,Dick I,Holt RA,Creaney J,Boon L,Robinson B,Lake RA
Published figure using CD8a monoclonal antibody (Product # 56-0081-82) in Flow Cytometry
Wed Mar 01 00:00:00 EST 2017
Targeted calcium influx boosts cytotoxic T lymphocyte function in the tumour microenvironment.
Nature communications
Kim KD,Bae S,Capece T,Nedelkovska H,de Rubio RG,Smrcka AV,Jun CD,Jung W,Park B,Kim TI,Kim M
Published figure using CD8a monoclonal antibody (Product # 56-0081-82) in Flow Cytometry
Mon May 15 00:00:00 EDT 2017
Location of tumor affects local and distant immune cell type and number.
Immunity, inflammation and disease
Hensel JA,Khattar V,Ashton R,Lee C,Siegal GP,Ponnazhagan S
Published figure using CD8a monoclonal antibody (Product # 56-0081-82) in Flow Cytometry
Wed Mar 01 00:00:00 EST 2017
Isolation of cell type-specific apoptotic bodies by fluorescence-activated cell sorting.
Scientific reports
Atkin-Smith GK,Paone S,Zanker DJ,Duan M,Phan TK,Chen W,Hulett MD,Poon IK
Published figure using CD8a monoclonal antibody (Product # 56-0081-82) in Flow Cytometry
Fri Jan 06 00:00:00 EST 2017
Adeno-associated virus serotype rh.10 displays strong muscle tropism following intraperitoneal delivery.
Scientific reports
Ai J,Li J,Gessler DJ,Su Q,Wei Q,Li H,Gao G
Published figure using CD8a monoclonal antibody (Product # 56-0081-82) in Immunofluorescence
Mon Jan 09 00:00:00 EST 2017
Identification of inhibitors of myeloid-derived suppressor cells activity through phenotypic chemical screening.
Oncoimmunology
Schröder M,Loos S,Naumann SK,Bachran C,Krötschel M,Umansky V,Helming L,Swee LK
Published figure using CD8a monoclonal antibody (Product # 56-0081-82) in Flow Cytometry
Tue Jan 12 00:00:00 EST 2021
IL-12 Influence mTOR to Modulate CD8+ T Cells Differentiation through T-bet and Eomesodermin in Response to Invasive Pulmonary Aspergillosis.
International journal of medical sciences
Wang H,Li J,Han Q,Yang F,Xiao Y,Xiao M,Xu Y,Su L,Cui N,Liu D
Published figure using CD8a monoclonal antibody (Product # 56-0081-82) in Flow Cytometry
Mon May 21 00:00:00 EDT 2018
Tristetraprolin inhibits macrophage IL-27-induced activation of antitumour cytotoxic T cell responses.
Nature communications
Wang Q,Ning H,Peng H,Wei L,Hou R,Hoft DF,Liu J
Published figure using CD8a monoclonal antibody (Product # 56-0081-82) in Flow Cytometry
Wed Oct 11 00:00:00 EDT 2017
IL-7-dependent STAT1 activation limits homeostatic CD4+ T cell expansion.
JCI insight
Le Saout C,Luckey MA,Villarino AV,Smith M,Hasley RB,Myers TG,Imamichi H,Park JH,O'Shea JJ,Lane HC,Catalfamo M
Published figure using CD8a monoclonal antibody (Product # 56-0081-82) in Flow Cytometry
Thu Nov 16 00:00:00 EST 2017
Potent single-domain antibodies that arrest respiratory syncytial virus fusion protein in its prefusion state.
Nature communications
Rossey I,Gilman MS,Kabeche SC,Sedeyn K,Wrapp D,Kanekiyo M,Chen M,Mas V,Spitaels J,Melero JA,Graham BS,Schepens B,McLellan JS,Saelens X
Published figure using CD8a monoclonal antibody (Product # 56-0081-82) in Flow Cytometry
Mon Feb 13 00:00:00 EST 2017
A Multistage Subunit Vaccine Effectively Protects Mice Against Primary Progressive Tuberculosis, Latency and Reactivation.
EBioMedicine
Ma J,Teng X,Wang X,Fan X,Wu Y,Tian M,Zhou Z,Li L
Published figure using CD8a monoclonal antibody (Product # 56-0081-82) in Flow Cytometry
Tue Aug 01 00:00:00 EDT 2017
Combined toll-like receptor 3/7/9 deficiency on host cells results in T-cell-dependent control of tumour growth.
Nature communications
Klein JC,Moses K,Zelinskyy G,Sody S,Buer J,Lang S,Helfrich I,Dittmer U,Kirschning CJ,Brandau S
56-0081 was used in Flow cytometry/Cell sorting to demonstrate that cells deficient in endosomal TLR3, 7 and 9 leads to tumour regression and anti-tumour immunity.
Thu Mar 16 00:00:00 EDT 2017
Metabolic maintenance of cell asymmetry following division in activated T lymphocytes.
Nature
Verbist KC,Guy CS,Milasta S,Liedmann S,Kamiński MM,Wang R,Green DR
Published figure using CD8a monoclonal antibody (Product # 56-0081-82) in Flow Cytometry
Thu Apr 21 00:00:00 EDT 2016
Metabolic maintenance of cell asymmetry following division in activated T lymphocytes.
Nature
Verbist KC,Guy CS,Milasta S,Liedmann S,Kamiński MM,Wang R,Green DR
Published figure using CD8a monoclonal antibody (Product # 56-0081-82) in Flow Cytometry
Thu Apr 21 00:00:00 EDT 2016
The Deubiquitinase OTULIN Is an Essential Negative Regulator of Inflammation and Autoimmunity.
Cell
Damgaard RB,Walker JA,Marco-Casanova P,Morgan NV,Titheradge HL,Elliott PR,McHale D,Maher ER,McKenzie ANJ,Komander D
Published figure using CD8a monoclonal antibody (Product # 56-0081-82) in Flow Cytometry
Thu Aug 25 00:00:00 EDT 2016
Maternal-Derived Hepatitis B Virus e Antigen Alters Macrophage Function in Offspring to Drive Viral Persistence after Vertical Transmission.
Immunity
Tian Y,Kuo CF,Akbari O,Ou JH
Published figure using CD8a monoclonal antibody (Product # 56-0081-82) in Flow Cytometry
Tue May 17 00:00:00 EDT 2016
Exploiting a host-commensal interaction to promote intestinal barrier function and enteric pathogen tolerance.
Science immunology
Pedicord VA,Lockhart AAK,Rangan KJ,Craig JW,Loschko J,Rogoz A,Hang HC,Mucida D
56-0081 was used in Flow cytometry/Cell sorting to demonstrate that specific factors from commensal bacteria can improve host barrier function and limit the pathogenesis of distinct enteric infections.
Thu Sep 01 00:00:00 EDT 2016
Oligodendrocyte death results in immune-mediated CNS demyelination.
Nature neuroscience
Traka M,Podojil JR,McCarthy DP,Miller SD,Popko B
Published figure using CD8a monoclonal antibody (Product # 56-0081-82) in Flow Cytometry
Fri Jan 01 00:00:00 EST 2016
TGF-β receptor maintains CD4 T helper cell identity during chronic viral infections.
The Journal of clinical investigation
Lewis GM,Wehrens EJ,Labarta-Bajo L,Streeck H,Zuniga EI
56-0081 was used in Flow cytometry/Cell sorting to uncover an eomesodermin-driven CD4 T cell program that is continuously suppressed by TGF-β signalling.
Mon Oct 03 00:00:00 EDT 2016
Neutrophil Extracellular Traps Enhance Early Inflammatory Response in Sendai Virus-Induced Asthma Phenotype.
Frontiers in immunology
Akk A,Springer LE,Pham CT
Published figure using CD8a monoclonal antibody (Product # 56-0081-82) in Flow Cytometry
Mon Sep 12 00:00:00 EDT 2016
Opposite Effects of Coinjection and Distant Injection of Mesenchymal Stem Cells on Breast Tumor Cell Growth.
Stem cells translational medicine
Zheng H,Zou W,Shen J,Xu L,Wang S,Fu YX,Fan W
Published figure using CD8a monoclonal antibody (Product # 56-0081-82) in Flow Cytometry
Thu Sep 01 00:00:00 EDT 2016
PRDM14 promotes RAG-dependent Notch1 driver mutations in mouse T-ALL.
Biology open
Carofino BL,Ayanga B,Tracey LJ,Brooke-Bisschop T,Justice MJ
Published figure using CD8a monoclonal antibody (Product # 56-0081-82) in Flow Cytometry
Sun May 15 00:00:00 EDT 2016
Stromal senescence establishes an immunosuppressive microenvironment that drives tumorigenesis.
Nature communications
Ruhland MK,Loza AJ,Capietto AH,Luo X,Knolhoff BL,Flanagan KC,Belt BA,Alspach E,Leahy K,Luo J,Schaffer A,Edwards JR,Longmore G,Faccio R,DeNardo DG,Stewart SA
Published figure using CD8a monoclonal antibody (Product # 56-0081-82) in Flow Cytometry
Wed Jun 08 00:00:00 EDT 2016
Epigallocatechin-3-gallate (EGCG) inhibits imiquimod-induced psoriasis-like inflammation of BALB/c mice.
BMC complementary and alternative medicine
Zhang S,Liu X,Mei L,Wang H,Fang F
Published figure using CD8a monoclonal antibody (Product # 56-0081-82) in Flow Cytometry
Wed Aug 31 00:00:00 EDT 2016
Discovery of a Metastatic Immune Escape Mechanism Initiated by the Loss of Expression of the Tumour Biomarker Interleukin-33.
Scientific reports
Saranchova I,Han J,Huang H,Fenninger F,Choi KB,Munro L,Pfeifer C,Welch I,Wyatt AW,Fazli L,Gleave ME,Jefferies WA
Published figure using CD8a monoclonal antibody (Product # 56-0081-82) in Flow Cytometry
Tue Sep 13 00:00:00 EDT 2016
Discovery of a Metastatic Immune Escape Mechanism Initiated by the Loss of Expression of the Tumour Biomarker Interleukin-33.
Scientific reports
Saranchova I,Han J,Huang H,Fenninger F,Choi KB,Munro L,Pfeifer C,Welch I,Wyatt AW,Fazli L,Gleave ME,Jefferies WA
Published figure using CD8a monoclonal antibody (Product # 56-0081-82) in Flow Cytometry
Tue Sep 13 00:00:00 EDT 2016
MHC-I and PirB Upregulation in the Central and Peripheral Nervous System following Sciatic Nerve Injury.
PloS one
Bombeiro AL,Thomé R,Oliveira Nunes SL,Monteiro Moreira B,Verinaud L,Oliveira AL
Published figure using CD8a monoclonal antibody (Product # 56-0081-82) in Immunofluorescence
Wed Jul 26 00:00:00 EDT 2017
Exploring the induction of preproinsulin-specific Foxp3(+) CD4(+) Treg cells that inhibit CD8(+) T cell-mediated autoimmune diabetes by DNA vaccination.
Scientific reports
Stifter K,Schuster C,Schlosser M,Boehm BO,Schirmbeck R
Published figure using CD8a monoclonal antibody (Product # 56-0081-82) in Flow Cytometry
Mon Jul 11 00:00:00 EDT 2016
Photothermal therapy with immune-adjuvant nanoparticles together with checkpoint blockade for effective cancer immunotherapy.
Nature communications
Chen Q,Xu L,Liang C,Wang C,Peng R,Liu Z
Published figure using CD8a monoclonal antibody (Product # 56-0081-82) in Flow Cytometry
Fri Oct 21 00:00:00 EDT 2016
Postsynaptic SDC2 induces transsynaptic signaling via FGF22 for bidirectional synaptic formation.
Scientific reports
Hu HT,Umemori H,Hsueh YP
Published figure using CD8a monoclonal antibody (Product # 56-0081-82) in Immunoprecipitation
Thu Sep 15 00:00:00 EDT 2016
Injectable, spontaneously assembling, inorganic scaffolds modulate immune cells in vivo and increase vaccine efficacy.
Nature biotechnology
Kim J,Li WA,Choi Y,Lewin SA,Verbeke CS,Dranoff G,Mooney DJ
Published figure using CD8a monoclonal antibody (Product # 56-0081-82) in Flow Cytometry
Thu Jan 01 00:00:00 EST 2015
FOXP3+ regulatory T cell development and function require histone/protein deacetylase 3.
The Journal of clinical investigation
Wang L,Liu Y,Han R,Beier UH,Bhatti TR,Akimova T,Greene MI,Hiebert SW,Hancock WW
Published figure using CD8a monoclonal antibody (Product # 56-0081-82) in Flow Cytometry
Mon Mar 02 00:00:00 EST 2015
Atypical chemokine receptor 1 deficiency reduces atherogenesis in ApoE-knockout mice.
Cardiovascular research
Wan W,Liu Q,Lionakis MS,Marino AP,Anderson SA,Swamydas M,Murphy PM
Published figure using CD8a monoclonal antibody (Product # 56-0081-82) in Flow Cytometry
Mon Jun 01 00:00:00 EDT 2015
MHC-mismatched mixed chimerism augments thymic regulatory T-cell production and prevents relapse of EAE in mice.
Proceedings of the National Academy of Sciences of the United States of America
Wu L,Li N,Zhang M,Xue SL,Cassady K,Lin Q,Riggs AD,Zeng D
Published figure using CD8a monoclonal antibody (Product # 56-0081-82) in Flow Cytometry
Tue Dec 29 00:00:00 EST 2015
CD31 signals confer immune privilege to the vascular endothelium.
Proceedings of the National Academy of Sciences of the United States of America
Cheung K,Ma L,Wang G,Coe D,Ferro R,Falasca M,Buckley CD,Mauro C,Marelli-Berg FM
Published figure using CD8a monoclonal antibody (Product # 56-0081-82) in Flow Cytometry
Tue Oct 27 00:00:00 EDT 2015
CD31 signals confer immune privilege to the vascular endothelium.
Proceedings of the National Academy of Sciences of the United States of America
Cheung K,Ma L,Wang G,Coe D,Ferro R,Falasca M,Buckley CD,Mauro C,Marelli-Berg FM
Published figure using CD8a monoclonal antibody (Product # 56-0081-82) in Flow Cytometry
Tue Oct 27 00:00:00 EDT 2015
Imaging Tolerance Induction in the Classic Medawar Neonatal Mouse Model: Active Roles of Multiple F1-Donor Cell Types.
American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons
Bascom RA,Tao KS,Tollenaar SL,West LJ
Published figure using CD8a monoclonal antibody (Product # 56-0081-82) in Immunocytochemistry
Tue Sep 01 00:00:00 EDT 2015
Single-Dose CpG Immunization Protects Against a Heterosubtypic Challenge and Generates Antigen-Specific Memory T Cells.
Frontiers in immunology
Vogel AJ,Brown DM
Published figure using CD8a monoclonal antibody (Product # 56-0081-82) in Flow Cytometry
Fri Jul 10 00:00:00 EDT 2015
T-bet Is Required for the Rapid Clearance of Attenuated Rabies Virus from Central Nervous System Tissue.
Journal of immunology (Baltimore, Md. : 1950)
Lebrun A,Portocarrero C,Kean RB,Barkhouse DA,Faber M,Hooper DC
Published figure using CD8a monoclonal antibody (Product # 56-0081-82) in Immunofluorescence
Sun Nov 01 00:00:00 EDT 2015
Leptin receptor signaling in T cells is required for Th17 differentiation.
Journal of immunology (Baltimore, Md. : 1950)
Reis BS,Lee K,Fanok MH,Mascaraque C,Amoury M,Cohn LB,Rogoz A,Dallner OS,Moraes-Vieira PM,Domingos AI,Mucida D
56-0081 was used in Flow cytometry/Cell sorting to show that leptin receptor signalling in T cells is required for Th17 differentiation.
Mon Jun 01 00:00:00 EDT 2015
A tumor lysate is an effective vaccine antigen for the stimulation of CD4(+) T-cell function and subsequent induction of antitumor immunity mediated by CD8(+) T cells.
Cancer biology & therapy
Kawahara M,Takaku H
Published figure using CD8a monoclonal antibody (Product # 56-0081-82) in Flow Cytometry
Mon Sep 12 00:00:00 EDT 2016
Adjuvants may reduce in vivo transfection levels for DNA vaccination in mice leading to reduced antigen-specific CD8+ T cell responses.
Human vaccines & immunotherapeutics
Rose AH,Hoffmann FW,Hara JH,Urschitz J,Moisyadi S,Hoffmann PR,Bertino P
Published figure using CD8a monoclonal antibody (Product # 56-0081-82) in Flow Cytometry
Mon May 16 00:00:00 EDT 2016
Immunogenicity and protective efficacy of DMT liposome-adjuvanted tuberculosis subunit CTT3H vaccine.
Human vaccines & immunotherapeutics
Teng X,Tian M,Li J,Tan S,Yuan X,Yu Q,Jing Y,Zhang Z,Yue T,Zhou L,Fan X
Published figure using CD8a monoclonal antibody (Product # 56-0081-82) in Flow Cytometry
Fri Mar 11 00:00:00 EST 2016
MFG-E8 Is Critical for Embryonic Stem Cell-Mediated T Cell Immunomodulation.
Stem cell reports
Tan Y,AlKhamees B,Jia D,Li L,Couture JF,Figeys D,Jinushi M,Wang L
Published figure using CD8a monoclonal antibody (Product # 56-0081-82) in Flow Cytometry
Tue Nov 10 00:00:00 EST 2015
MFG-E8 Is Critical for Embryonic Stem Cell-Mediated T Cell Immunomodulation.
Stem cell reports
Tan Y,AlKhamees B,Jia D,Li L,Couture JF,Figeys D,Jinushi M,Wang L
Published figure using CD8a monoclonal antibody (Product # 56-0081-82) in Flow Cytometry
Tue Nov 10 00:00:00 EST 2015
Use of tilapia piscidin 3 (TP3) to protect against MRSA infection in mice with skin injuries.
Oncotarget
Huang HN,Chan YL,Hui CF,Wu JL,Wu CJ,Chen JY
Published figure using CD8a monoclonal antibody (Product # 56-0081-82) in Immunohistochemistry
Sat May 30 00:00:00 EDT 2015
Favorable alteration of tumor microenvironment by immunomodulatory cytokines for efficient T-cell therapy in solid tumors.
PloS one
Tähtinen S,Kaikkonen S,Merisalo-Soikkeli M,Grönberg-Vähä-Koskela S,Kanerva A,Parviainen S,Vähä-Koskela M,Hemminki A
Published figure using CD8a monoclonal antibody (Product # 56-0081-82) in Flow Cytometry
Thu Apr 28 00:00:00 EDT 2016
Designed ankyrin repeat proteins are effective targeting elements for chimeric antigen receptors.
Journal for immunotherapy of cancer
Hammill JA,VanSeggelen H,Helsen CW,Denisova GF,Evelegh C,Tantalo DG,Bassett JD,Bramson JL
56-0081 was used in Flow cytometry/Cell sorting to investigate the production of chimeric antigen receptors with novel antigen binding attributes.
Thu Dec 17 00:00:00 EST 2015
Near-infrared photoactivatable control of Ca(2+) signaling and optogenetic immunomodulation.
eLife
He L,Zhang Y,Ma G,Tan P,Li Z,Zang S,Wu X,Jing J,Fang S,Zhou L,Wang Y,Huang Y,Hogan PG,Han G,Zhou Y
Published figure using CD8a monoclonal antibody (Product # 56-0081-82) in Flow Cytometry
Tue Dec 08 00:00:00 EST 2015
T cell responses are elicited against Respiratory Syncytial Virus in the absence of signalling through TLRs, RLRs and IL-1R/IL-18R.
Scientific reports
Goritzka M,Pereira C,Makris S,Durant LR,Johansson C
56-0081 was used in Flow cytometry/Cell sorting to highlight an unappreciated level of redundancy in pathways that couple innate virus sensing to adaptive immunity.
Mon Dec 21 00:00:00 EST 2015
An autologous leukemia cell vaccine prevents murine acute leukemia relapse after cytarabine treatment.
Blood
Gibbins JD,Ancelet LR,Weinkove R,Compton BJ,Painter GF,Petersen TR,Hermans IF
56-0081 was used in Flow cytometry/Cell sorting to investigate the efficacy of an intravenously administered vaccine consisting of irradiated leukemia cells loaded with α-GalCer.
Thu Nov 06 00:00:00 EST 2014
Experimental cerebral malaria pathogenesis--hemodynamics at the blood brain barrier.
PLoS pathogens
Nacer A,Movila A,Sohet F,Girgis NM,Gundra UM,Loke P,Daneman R,Frevert U
56-0081 was used in Flow cytometry/Cell sorting to show that significantly more CD8(+) T cells, neutrophils, and macrophages are recruited to postcapillary venules during ECM compared to hyperparasitemia.
Mon Dec 01 00:00:00 EST 2014
Conditional deletion of ferritin h in mice reduces B and T lymphocyte populations.
PloS one
Vanoaica L,Richman L,Jaworski M,Darshan D,Luther SA,Kühn LC
56-0081 was used in Flow cytometry/Cell sorting to investigate the effect of ferritin H deletion on lymphocytes, showing that it reduces B and T lymphocyte populations.
Tue Jan 13 00:00:00 EST 2015
A new animal model of spontaneous autoimmune peripheral polyneuropathy: implications for Guillain-Barré syndrome.
Acta neuropathologica communications
Yang M,Rainone A,Shi XQ,Fournier S,Zhang J
Published figure using CD8a monoclonal antibody (Product # 56-0081-82) in Flow Cytometry
Wed Jan 08 00:00:00 EST 2014
Deficiency of autophagy in dendritic cells protects against experimental autoimmune encephalomyelitis.
The Journal of biological chemistry
Bhattacharya A,Parillon X,Zeng S,Han S,Eissa NT
Published figure using CD8a monoclonal antibody (Product # 56-0081-82) in Flow Cytometry
Fri Sep 19 00:00:00 EDT 2014
Mutual expression of the transcription factors Runx3 and ThPOK regulates intestinal CD4⁺ T cell immunity.
Nature immunology
Reis BS,Rogoz A,Costa-Pinto FA,Taniuchi I,Mucida D
56-0081 was used in Flow cytometry/Cell sorting to demonstrate plasticity in the CD4(+) T cell lineage that allows chronic exposure to luminal antigens without pathological inflammation.
Fri Mar 01 00:00:00 EST 2013
The transcription factor STAT5 is critical in dendritic cells for the development of TH2 but not TH1 responses.
Nature immunology
Bell BD,Kitajima M,Larson RP,Stoklasek TA,Dang K,Sakamoto K,Wagner KU,Kaplan DH,Reizis B,Hennighausen L,Ziegler SF
56-0081 was used in Flow cytometry/Cell sorting to investigate how type-2 immunity is affected by STAT5 transcription factor in dendritic cells.
Mon Apr 01 00:00:00 EDT 2013
Dose-dense chemotherapy improves mechanisms of antitumor immune response.
Cancer research
Chang CL,Hsu YT,Wu CC,Lai YZ,Wang C,Yang YC,Wu TC,Hung CF
Published figure using CD8a monoclonal antibody (Product # 56-0081-82) in Flow Cytometry
Tue Jan 01 00:00:00 EST 2013
Genetic deletion of chemokine receptor Ccr7 exacerbates atherogenesis in ApoE-deficient mice.
Cardiovascular research
Wan W,Lionakis MS,Liu Q,Roffê E,Murphy PM
Published figure using CD8a monoclonal antibody (Product # 56-0081-82) in Flow Cytometry
Fri Mar 01 00:00:00 EST 2013
A mouse model for inducible overexpression of Prdm14 results in rapid-onset and highly penetrant T-cell acute lymphoblastic leukemia (T-ALL).
Disease models & mechanisms
Carofino BL,Ayanga B,Justice MJ
Published figure using CD8a monoclonal antibody (Product # 56-0081-82) in Flow Cytometry
Fri Nov 01 00:00:00 EDT 2013
Interleukin-22 as a molecular adjuvant facilitates IL-17-producing CD8+ T cell responses against a HBV DNA vaccine in mice.
Human vaccines & immunotherapeutics
Wu B,Zou Q,Hu Y,Wang B
Published figure using CD8a monoclonal antibody (Product # 56-0081-82) in Flow Cytometry
Tue Oct 01 00:00:00 EDT 2013
In vivo CD8+ T cell dynamics in the liver of Plasmodium yoelii immunized and infected mice.
PloS one
Cabrera M,Pewe LL,Harty JT,Frevert U
Published figure using CD8a monoclonal antibody (Product # 56-0081-82) in Immunofluorescence
Tue Mar 18 00:00:00 EDT 2014
In vivo CD8+ T cell dynamics in the liver of Plasmodium yoelii immunized and infected mice.
PloS one
Cabrera M,Pewe LL,Harty JT,Frevert U
Published figure using CD8a monoclonal antibody (Product # 56-0081-82) in Immunofluorescence
Tue Mar 18 00:00:00 EDT 2014
A missing PD-L1/PD-1 coinhibition regulates diabetes induction by preproinsulin-specific CD8 T-cells in an epitope-specific manner.
PloS one
Schuster C,Brosi H,Stifter K,Boehm BO,Schirmbeck R
Published figure using CD8a monoclonal antibody (Product # 56-0081-82) in Immunofluorescence
Tue Apr 08 00:00:00 EDT 2014
A missing PD-L1/PD-1 coinhibition regulates diabetes induction by preproinsulin-specific CD8 T-cells in an epitope-specific manner.
PloS one
Schuster C,Brosi H,Stifter K,Boehm BO,Schirmbeck R
Published figure using CD8a monoclonal antibody (Product # 56-0081-82) in Immunofluorescence
Tue Apr 08 00:00:00 EDT 2014
Gr1(int)CD11b+ myeloid-derived suppressor cells in Mycobacterium tuberculosis infection.
PloS one
Obregón-Henao A,Henao-Tamayo M,Orme IM,Ordway DJ
56-0081 was used in Flow cytometry/Cell sorting to compare the bacterial burden, lung pathology and Gr1(int)CD11b(+) myeloid-derived suppressor cell immune responses in M. tuberculosis infected mice.
Fri Jun 20 00:00:00 EDT 2014
TDP2-dependent non-homologous end-joining protects against topoisomerase II-induced DNA breaks and genome instability in cells and in vivo.
PLoS genetics
Gómez-Herreros F,Romero-Granados R,Zeng Z,Alvarez-Quilón A,Quintero C,Ju L,Umans L,Vermeire L,Huylebroeck D,Caldecott KW,Cortés-Ledesma F
Published figure using CD8a monoclonal antibody (Product # 56-0081-82) in Flow Cytometry
Thu Jun 13 00:00:00 EDT 2013
Skin thymic stromal lymphopoietin initiates Th2 responses through an orchestrated immune cascade.
Nature communications
Leyva-Castillo JM,Hener P,Michea P,Karasuyama H,Chan S,Soumelis V,Li M
56-0081 was used in Flow cytometry/Cell sorting to investigate the mechanisms by which thymic stromal lymphopoietin leads to Th2 initiation, showing that it occurs through an orchestrated immune cascade.
Tue Oct 07 00:00:00 EDT 2014
Plasmacytoid dendritic cells transport peripheral antigens to the thymus to promote central tolerance.
Immunity
Hadeiba H,Lahl K,Edalati A,Oderup C,Habtezion A,Pachynski R,Nguyen L,Ghodsi A,Adler S,Butcher EC
56-0081 was used in Flow cytometry/Cell sorting to explore the mechanisms underlying the contribution to immune tolerance conducted by peripheral dendritic cells.
Fri Mar 23 00:00:00 EDT 2012
Absence of Wip1 partially rescues Atm deficiency phenotypes in mice.
Oncogene
Darlington Y,Nguyen TA,Moon SH,Herron A,Rao P,Zhu C,Lu X,Donehower LA
Published figure using CD8a monoclonal antibody (Product # 56-0081-82) in Flow Cytometry
Thu Mar 01 00:00:00 EST 2012
Preserved function of regulatory T cells in chronic HIV-1 infection despite decreased numbers in blood and tissue.
The Journal of infectious diseases
Angin M,Kwon DS,Streeck H,Wen F,King M,Rezai A,Law K,Hongo TC,Pyo A,Piechocka-Trocha A,Toth I,Pereyra F,Ghebremichael M,Rodig SJ,Milner DA,Richter JM,Altfeld M,Kaufmann DE,Walker BD,Addo MM
56-0081 was used in Flow cytometry/Cell sorting to study the frequency and function of Tregs in HIV-1-infected individuals.
Tue May 15 00:00:00 EDT 2012
Evaluation of Lassa virus vaccine immunogenicity in a CBA/J-ML29 mouse model.
Vaccine
Goicochea MA,Zapata JC,Bryant J,Davis H,Salvato MS,Lukashevich IS
Published figure using CD8a monoclonal antibody (Product # 56-0081-82) in Flow Cytometry
Tue Feb 14 00:00:00 EST 2012
Characterization of transgenic mice expressing cancer-associated variants of human NOTCH1.
Genesis (New York, N.Y. : 2000)
Berquam-Vrieze KE,Swing DA,Tessarollo L,Dupuy AJ
Published figure using CD8a monoclonal antibody (Product # 56-0081-82) in Flow Cytometry
Wed Feb 01 00:00:00 EST 2012
Sensitized phenotypic screening identifies gene dosage sensitive region on chromosome 11 that predisposes to disease in mice.
EMBO molecular medicine
Ermakova O,Piszczek L,Luciani L,Cavalli FM,Ferreira T,Farley D,Rizzo S,Paolicelli RC,Al-Banchaabouchi M,Nerlov C,Moriggl R,Luscombe NM,Gross C
Published figure using CD8a monoclonal antibody (Product # 56-0081-82) in Flow Cytometry
Sat Jan 01 00:00:00 EST 2011
T cell factor 1 regulates thymocyte survival via a RORγt-dependent pathway.
Journal of immunology (Baltimore, Md. : 1950)
Wang R,Xie H,Huang Z,Ma J,Fang X,Ding Y,Sun Z
Published figure using CD8a monoclonal antibody (Product # 56-0081-82) in Flow Cytometry
Thu Dec 01 00:00:00 EST 2011
Functional redundancy between thymic CD8α+ and Sirpα+ conventional dendritic cells in presentation of blood-derived lysozyme by MHC class II proteins.
Journal of immunology (Baltimore, Md. : 1950)
Atibalentja DF,Murphy KM,Unanue ER
56-0081 was used in Flow cytometry/Cell sorting to evaluate the presentation of blood-derived protein Ags by antigen presenting cells in the thymus.
Tue Feb 01 00:00:00 EST 2011
Early MyD88-dependent induction of interleukin-17A expression during Salmonella colitis.
Infection and immunity
Keestra AM,Godinez I,Xavier MN,Winter MG,Winter SE,Tsolis RM,Bäumler AJ
56-0081 was used in Flow cytometry/Cell sorting to demonstrate that myeloid differentiation primary response protein 88-dependent mechanisms are important in initiating early inflammatory responses during Salmonella colitis.
Mon Aug 01 00:00:00 EDT 2011
Continuous activation of the CD122/STAT-5 signaling pathway during selection of antigen-specific regulatory T cells in the murine thymus.
PloS one
Goldstein JD,Balderas RS,Marodon G
56-0081 was used in Flow cytometry/Cell sorting to report higher levels of phosphorylated STAT-5 in nTreg cells in the murine thymus and, to a lesser extent, in the periphery compared to other CD4(+)CD8(-) subsets.
Tue Apr 26 00:00:00 EDT 2011
T cells recognizing a peptide contaminant undetectable by mass spectrometry.
PloS one
Brezar V,Culina S,Østerbye T,Guillonneau F,Chiappetta G,Verdier Y,Vinh J,Wong FS,Buus S,Mallone R
56-0081 was used in Flow cytometry/Cell sorting to characterise novel MHC Class-I-restricted β-cell epitopes in non-obese diabetic mice.
Mon Aug 27 00:00:00 EDT 2012
The AIM2 inflammasome is essential for host defense against cytosolic bacteria and DNA viruses.
Nature immunology
Rathinam VA,Jiang Z,Waggoner SN,Sharma S,Cole LE,Waggoner L,Vanaja SK,Monks BG,Ganesan S,Latz E,Hornung V,Vogel SN,Szomolanyi-Tsuda E,Fitzgerald KA
56-0081 was used in Immunofluorescence to study the AIM2 inflammasome which is important in the sensing of both bacterial and viral pathogens and in triggering innate immunity.
Sat May 01 00:00:00 EDT 2010
Partial restoration of T-cell function in aged mice by in vitro blockade of the PD-1/ PD-L1 pathway.
Aging cell
Lages CS,Lewkowich I,Sproles A,Wills-Karp M,Chougnet C
56-0081 was used in Flow cytometry/Cell sorting to suggest that blockade of the PD-1/PD-L1 is not likely to be efficient at restoring exhausted T-cell responses in aged hosts.
Fri Oct 01 00:00:00 EDT 2010
Interleukin-23 orchestrates mucosal responses to Salmonella enterica serotype Typhimurium in the intestine.
Infection and immunity
Godinez I,Raffatellu M,Chu H,Paixão TA,Haneda T,Santos RL,Bevins CL,Tsolis RM,Bäumler AJ
56-0081 was used in Flow cytometry/Cell sorting to investigate the role of IL-23 in initiating inflammatory responses to Salmonella enterica serotype Typhimurium in streptomycin-pretreated mice.
Thu Jan 01 00:00:00 EST 2009
Suppression of alkali burn-induced corneal neovascularization by dendritic cell vaccination targeting VEGF receptor 2.
Investigative ophthalmology & visual science
Mochimaru H,Usui T,Yaguchi T,Nagahama Y,Hasegawa G,Usui Y,Shimmura S,Tsubota K,Amano S,Kawakami Y,Ishida S
Thu May 01 00:00:00 EDT 2008
Inactivation of the type IV secretion system reduces the Th1 polarization of the immune response to Brucella abortus infection.
Infection and immunity
Rolán HG,Tsolis RM
56-0081 was used in Flow cytometry/Cell sorting to investigate how early differences in cytokine responses contribute to a stronger Th1 polarization of the immune response in mice infected with wild-type B. abortus than in mice infected with the virB mutant.
Tue Jul 01 00:00:00 EDT 2008
Myocardial infarct-sparing effect of adenosine A2A receptor activation is due to its action on CD4+ T lymphocytes.
Circulation
Yang Z,Day YJ,Toufektsian MC,Xu Y,Ramos SI,Marshall MA,French BA,Linden J
Tue Nov 07 00:00:00 EST 2006
An MHC-linked locus modulates thymic differentiation of CD4+CD25+Foxp3+ regulatory T lymphocytes.
International immunology
Tellier J,van Meerwijk JP,Romagnoli P
56-0081 was used in Flow cytometry/Cell sorting to investigate factors that affect the levels of Tregs in the thymus.
Wed Nov 01 00:00:00 EST 2006
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.jpg?time=20240507?time=20240507 "CD8a Antibody (56-0081-82) in ICC/IF")
.jpg?time=20240507?time=20240507 "CD8a Antibody (56-0081-82) in ICC/IF")
