Product References
A single-cell transcriptional atlas reveals resident progenitor cell niche functions in TMJ disc development and injury.
Nature communications
Bi R,Yin Q,Li H,Yang X,Wang Y,Li Q,Fang H,Li P,Lyu P,Fan Y,Ying B,Zhu S
Published figure using CD90.2 (Thy-1.2) monoclonal antibody (Product # 47-0902-82) in Flow Cytometry
Tue Feb 14 00:00:00 EST 2023
Hyaline cartilage differentiation of fibroblasts in regeneration and regenerative medicine.
Development (Cambridge, England)
Yu L,Lin YL,Yan M,Li T,Wu EY,Zimmel K,Qureshi O,Falck A,Sherman KM,Huggins SS,Hurtado DO,Suva LJ,Gaddy D,Cai J,Brunauer R,Dawson LA,Muneoka K
47-0902-82 was used in Flow Cytometry to identify fibroblasts as a novel source for hyaline cartilage regeneration, and BMP9 as a potent inducer of hyaline and articular chondrocyte differentiation.
Sat Jan 15 00:00:00 EST 2022
Partial Tendon Injury at the Tendon-to-Bone Enthesis Activates Skeletal Stem Cells.
Stem cells translational medicine
Titan AL,Davitt M,Foster D,Salhotra A,Menon S,Chen K,Fahy E,Lopez M,Jones RE,Baiu I,Burcham A,Januszyk M,Gurtner G,Fox P,Chan C,Quarto N,Longaker M
47-0902-82 was used in Flow cytometry/Cell sorting to evaluate the putative role of mouse skeletal stem cells (mSSCs) in the enthesis after partial-injury.
Wed Jul 20 00:00:00 EDT 2022
Therapeutic Potential of Mesenchymal Stem Cells in a Pre-Clinical Model of Diabetic Kidney Disease and Obesity.
International journal of molecular sciences
Sávio-Silva C,Soinski-Sousa PE,Simplício-Filho A,Bastos RMC,Beyerstedt S,Rangel ÉB
Published figure using CD90.2 (Thy-1.2) monoclonal antibody (Product # 47-0902-82) in Flow Cytometry
Thu Feb 04 00:00:00 EST 2021
Heterogeneity of murine periosteum progenitors involved in fracture healing.
eLife
Matthews BG,Novak S,Sbrana FV,Funnell JL,Cao Y,Buckels EJ,Grcevic D,Kalajzic I
47-0902-82 was used in Flow Cytometry to demonstrate that the periosteum is highly enriched with skeletal progenitor cells, and there is heterogeneity in the populations of cells that contribute to mature lineages during periosteal fracture healing.
Tue Feb 09 00:00:00 EST 2021
TNF-α-induced alterations in stromal progenitors enhance leukemic stem cell growth via CXCR2 signaling.
Cell reports
Agarwal P,Li H,Choi K,Hueneman K,He J,Welner RS,Starczynowski DT,Bhatia R
47-0902-82 was used in Flow Cytometry to find that TNF-α-mediated alterations in CML BM stromal niches enhance support of LSC maintenance and growth via CXCL1-CXCR2 signaling and that CXCR2 inhibition effectively depletes CML LSCs.
Tue Jul 13 00:00:00 EDT 2021
Distinct skeletal stem cell types orchestrate long bone skeletogenesis.
eLife
Ambrosi TH,Sinha R,Steininger HM,Hoover MY,Murphy MP,Koepke LS,Wang Y,Lu WJ,Morri M,Neff NF,Weissman IL,Longaker MT,Chan CK
47-0902-82 was used in Flow Cytometry to address previously unappreciated shortcomings of SSC research.
Mon Jul 19 00:00:00 EDT 2021
Single-Cell Analyses Inform Mechanisms of Myeloid-Targeted Therapies in Colon Cancer.
Cell
Zhang L,Li Z,Skrzypczynska KM,Fang Q,Zhang W,O'Brien SA,He Y,Wang L,Zhang Q,Kim A,Gao R,Orf J,Wang T,Sawant D,Kang J,Bhatt D,Lu D,Li CM,Rapaport AS,Perez K,Ye Y,Wang S,Hu X,Ren X,Ouyang W,Shen Z,Egen JG,Zhang Z,Yu X
47-0902-82 was used in Flow Cytometry to identify critical cellular interactions regulating tumor immunity and defines mechanisms underlying myeloid-targeted immunotherapies currently undergoing clinical testing.
Thu Apr 16 00:00:00 EDT 2020
Transplantation tolerance modifies donor-specific B cell fate to suppress de novo alloreactive B cells.
The Journal of clinical investigation
Khiew SH,Jain D,Chen J,Yang J,Yin D,Young JS,Dent A,Sciammas R,Alegre ML,Chong AS
47-0902 was used in Flow cytometry/Cell sorting to showed that alloreactive B cells were not deleted but rapidly lost their ability to differentiate into germinal center B cells and secrete donor-specific antibodies., by using a murine model of heart tolerance.
Wed Jul 01 00:00:00 EDT 2020
Extracellular HMGB-1 activates inflammatory signaling in tendon cells and tissues.
Therapeutic advances in chronic disease
Zhang C,Gu X,Zhao G,Wang W,Shao J,Zhu J,Yuan T,Sun J,Nie D,Zhou Y
Published figure using CD90.2 (Thy-1.2) monoclonal antibody (Product # 47-0902-82) in Flow Cytometry
Sun Apr 17 00:00:00 EDT 2022
Pyruvate kinase M2 in lung APCs regulates Alternaria-induced airway inflammation.
Immunobiology
Jaiswal AK,Makhija S,Stahr N,Sandey M,Suryawanshi A,Mishra A
47-0902-82 was used in Flow Cytometry to support a model in which Alternaria sensitization in airways induce a circuitry of glycolysis and PKM2 regulation that confers an acute activation of APCs in the lung, whose targeting might represent a strategy for asthma treatment.
Wed Jul 01 00:00:00 EDT 2020
Loss of Fas signaling in fibroblasts impairs homeostatic fibrosis resolution and promotes persistent pulmonary fibrosis.
JCI insight
Redente EF,Chakraborty S,Sajuthi S,Black BP,Edelman BL,Seibold MA,Riches DW
Published figure using CD90.2 (Thy-1.2) monoclonal antibody (Product # 47-0902-82) in Flow Cytometry
Tue Dec 08 00:00:00 EST 2020
Cardiac fibroblast proliferation rates and collagen expression mature early and are unaltered with advancing age.
JCI insight
Wu R,Ma F,Tosevska A,Farrell C,Pellegrini M,Deb A
Published figure using CD90.2 (Thy-1.2) monoclonal antibody (Product # 47-0902-82) in Flow Cytometry
Thu Dec 17 00:00:00 EST 2020
Transcriptional Basis of Mouse and Human Dendritic Cell Heterogeneity.
Cell
Brown CC,Gudjonson H,Pritykin Y,Deep D,Lavallée VP,Mendoza A,Fromme R,Mazutis L,Ariyan C,Leslie C,Pe'er D,Rudensky AY
47-0902 was used in Flow cytometry/Cell sorting to identify two principal cDC2 lineages defined by distinct developmental pathways and transcriptional regulators, including T-bet and RORγt, two key transcription factors known to define innate and adaptive lymphocyte subsets.
Thu Oct 31 00:00:00 EDT 2019
Cell-Type-Specific Responses to Interleukin-1 Control Microbial Invasion and Tumor-Elicited Inflammation in Colorectal Cancer.
Immunity
Dmitrieva-Posocco O,Dzutsev A,Posocco DF,Hou V,Yuan W,Thovarai V,Mufazalov IA,Gunzer M,Shilovskiy IP,Khaitov MR,Trinchieri G,Waisman A,Grivennikov SI
47-0902-82 was used in Flow Cytometry to examine the impact of IL-1 signaling, a key regulator of the IL-17 pathway, in different cell types within the CRC microenvironment.
Tue Jan 15 00:00:00 EST 2019
Functional Heterogeneity of Mouse Prostate Stromal Cells Revealed by Single-Cell RNA-Seq.
iScience
Kwon OJ,Zhang Y,Li Y,Wei X,Zhang L,Chen R,Creighton CJ,Xin L
47-0902 was used in Flow cytometry/Cell sorting to characterise mouse Prostate stromal cells heterogeneity by single-cell RNA-seq.
Fri Mar 29 00:00:00 EDT 2019
E3 Ligase VHL Promotes Group 2 Innate Lymphoid Cell Maturation and Function via Glycolysis Inhibition and Induction of Interleukin-33 Receptor.
Immunity
Li Q,Li D,Zhang X,Wan Q,Zhang W,Zheng M,Zou L,Elly C,Lee JH,Liu YC
47-0902 was used in Flow Cytometry to indicate that the VHL-HIF-glycolysis axis is essential for the late-stage maturation and function of ILC2s via targeting IL-33-ST2 pathway.
Tue Feb 20 00:00:00 EST 2018
Isolation and functional assessment of mouse skeletal stem cell lineage.
Nature protocols
Gulati GS,Murphy MP,Marecic O,Lopez M,Brewer RE,Koepke LS,Manjunath A,Ransom RC,Salhotra A,Weissman IL,Longaker MT,Chan CKF
47-0902-82 was used in flow cytometry to describe a flow cytometry-based approach that does not require flow cytometry selection and that uses eight surface markers to distinguish and isolate mouse skeletal stem cells (mSSCs); bone, cartilage, and stromal progenitors (mBCSPs); and five downstream differentiated subtypes, including chondroprogenitors, two types of osteoprogenitors, and two types of hematopoiesis-supportive stroma.
Fri Jun 01 00:00:00 EDT 2018
De Novo Fatty Acid Synthesis During Mycobacterial Infection Is a Prerequisite for the Function of Highly Proliferative T Cells, But Not for Dendritic Cells or Macrophages.
Frontiers in immunology
Stüve P,Minarrieta L,Erdmann H,Arnold-Schrauf C,Swallow M,Guderian M,Krull F,Hölscher A,Ghorbani P,Behrends J,Abraham WR,Hölscher C,Sparwasser TD,Berod L
47-0902-82 was used in Flow Cytometry to reveal that acetyl-CoA carboxylase 1-dependent fatty acid synthesis is a crucial mechanism in T cells, but not dendritic cells or macrophages, to fight against mycobacterial infection.
Wed Apr 10 00:00:00 EDT 2019
Ultrasound Guided Intra-thymic Injection to Track Recent Thymic Emigrants and Investigate T Cell Development.
Bio-protocol
Wang H,Owen DL,Qian LJ,Chopp LB,Farrar MA,Hogquist KA
47-0902-82 was used in Flow cytometry/Cell sorting to introduce an ultrasound guided intra-thymic injection procedure, which is non-surgical and minimally invasive to animals.
Wed Dec 05 00:00:00 EST 2018
Mutations in 5-methylcytosine oxidase TET2 and RhoA cooperatively disrupt T cell homeostasis.
The Journal of clinical investigation
Zang S,Li J,Yang H,Zeng H,Han W,Zhang J,Lee M,Moczygemba M,Isgandarova S,Yang Y,Zhou Y,Rao A,You MJ,Sun D,Huang Y
Published figure using CD90.2 (Thy-1.2) monoclonal antibody (Product # 47-0902-82) in Flow Cytometry
Tue Aug 01 00:00:00 EDT 2017
IL33-mediated ILC2 activation and neutrophil IL5 production in the lung response after severe trauma: A reverse translation study from a human cohort to a mouse trauma model.
PLoS medicine
Xu J,Guardado J,Hoffman R,Xu H,Namas R,Vodovotz Y,Xu L,Ramadan M,Brown J,Turnquist HR,Billiar TR
47-0902 was used in Flow cytometry/Cell sorting to suggest that IL33 may initiate early detrimental type 2 immune responses after trauma through ILC2 regulation of neutrophil IL5 production.
Sat Jul 01 00:00:00 EDT 2017
Bacillus anthracis lethal toxin negatively modulates ILC3 function through perturbation of IL-23-mediated MAPK signaling.
PLoS pathogens
Seshadri S,Allan DSJ,Carlyle JR,Zenewicz LA
47-0902 was used in Flow cytometry/Cell sorting to study the effects of MAPK signalling pathways in group 3 innate immune lymphocytes using Bacillus anthracis.
Sun Oct 01 00:00:00 EDT 2017
Cross-Presentation of Soluble and Cell-Associated Antigen by Murine Hepatocytes Is Enhanced by Collectrin Expression.
Journal of immunology (Baltimore, Md. : 1950)
Dolina JS,Cechova S,Rudy CK,Sung SJ,Tang WW,Lee J,Hahn YS,Le TH
47-0902 was used in Flow cytometry/Cell sorting to identify the functional role of collectrin in the liver.
Wed Mar 15 00:00:00 EDT 2017
Simultaneous Intranasal/Intravascular Antibody Labeling of CD4+ T Cells in Mouse Lungs.
Bio-protocol
Wang Y,Sun J,Channappanavar R,Zhao J,Perlman S,Zhao J
47-0902 was used in Flow cytometry/Cell sorting to study the methods useful for characterising CD4 T cells in different anatomic locations in mouse lungs.
Thu Jan 05 00:00:00 EST 2017
Group A Streptococcus intranasal infection promotes CNS infiltration by streptococcal-specific Th17 cells.
The Journal of clinical investigation
Dileepan T,Smith ED,Knowland D,Hsu M,Platt M,Bittner-Eddy P,Cohen B,Southern P,Latimer E,Harley E,Agalliu D,Cleary PP
47-0902 was used in Flow cytometry/Cell sorting to elucidate the immunopathological contribution of Group A streptococci (GAS)-specific CD4+ T cells in the induced neuropathology following infection with GAS.
Fri Jan 01 00:00:00 EST 2016
IL-23 induced in keratinocytes by endogenous TLR4 ligands polarizes dendritic cells to drive IL-22 responses to skin immunization.
The Journal of experimental medicine
Yoon J,Leyva-Castillo JM,Wang G,Galand C,Oyoshi MK,Kumar L,Hoff S,He R,Chervonsky A,Oppenheim JJ,Kuchroo VK,van den Brink MR,Malefyt Rde W,Tessier PA,Fuhlbrigge R,Rosenstiel P,Terhorst C,Murphy G,Geha RS
47-0902 was used in Flow cytometry/Cell sorting to elucidate the mechanisms behind DC-derived IL-23 in a model of skin inflammation.
Mon Sep 19 00:00:00 EDT 2016
Lymphatic Contribution to the Cellular Niche in Heterotopic Ossification.
Annals of surgery
Loder S,Agarwal S,Sorkin M,Breuler C,Li J,Peterson J,Gardenier J,Hsieh HH,Wang SC,Mehrara BJ,Levi B
Published figure using CD90.2 (Thy-1.2) monoclonal antibody (Product # 47-0902-82) in Flow Cytometry
Thu Dec 01 00:00:00 EST 2016
Mucosal production of uric acid by airway epithelial cells contributes to particulate matter-induced allergic sensitization.
Mucosal immunology
Gold MJ,Hiebert PR,Park HY,Stefanowicz D,Le A,Starkey MR,Deane A,Brown AC,Liu G,Horvat JC,Ibrahim ZA,Sukkar MB,Hansbro PM,Carlsten C,VanEeden S,Sin DD,McNagny KM,Knight DA,Hirota JA
47-0902 was used in Flow cytometry/Cell sorting to investigate the mechanisms governing induction of innate immune responses and allergic sensitisation by particulate matter.
Sun May 01 00:00:00 EDT 2016
One Episode of Self-Resolving Plasmodium yoelii Infection Transiently Exacerbates Chronic Mycobacterium tuberculosis Infection.
Frontiers in microbiology
Blank J,Eggers L,Behrends J,Jacobs T,Schneider BE
47-0902 was used in Flow cytometry/Cell sorting to conclude that one episode of P. yoelii co-infection transiently exacerbated disease severity but had no long-term consequences on disease progression and survival of M. tuberculosis infected mice.
Thu Feb 25 00:00:00 EST 2016
Injectable, spontaneously assembling, inorganic scaffolds modulate immune cells in vivo and increase vaccine efficacy.
Nature biotechnology
Kim J,Li WA,Choi Y,Lewin SA,Verbeke CS,Dranoff G,Mooney DJ
Published figure using CD90.2 (Thy-1.2) monoclonal antibody (Product # 47-0902-82) in Flow Cytometry
Thu Jan 01 00:00:00 EST 2015
Disruption of p21-activated kinase 1 gene diminishes atherosclerosis in apolipoprotein E-deficient mice.
Nature communications
Singh NK,Kotla S,Dyukova E,Traylor JG,Orr AW,Chernoff J,Marion TN,Rao GN
Published figure using CD90.2 (Thy-1.2) monoclonal antibody (Product # 47-0902-82) in Flow Cytometry
Wed Jun 24 00:00:00 EDT 2015
Developmental heterogeneity of cardiac fibroblasts does not predict pathological proliferation and activation.
Circulation research
Ali SR,Ranjbarvaziri S,Talkhabi M,Zhao P,Subat A,Hojjat A,Kamran P,Müller AM,Volz KS,Tang Z,Red-Horse K,Ardehali R
47-0902 was used in Flow cytometry/Cell sorting to study the developmental origins of cardiac fibroblasts and characterise their corresponding phenotypes, to aid in determining the proliferation rates of each developmental subset.
Fri Sep 12 00:00:00 EDT 2014
Intravascular staining for discrimination of vascular and tissue leukocytes.
Nature protocols
Anderson KG,Mayer-Barber K,Sung H,Beura L,James BR,Taylor JJ,Qunaj L,Griffith TS,Vezys V,Barber DL,Masopust D
47-0902 was used in Flow cytometry/Cell sorting to outline a protocol for the validation and use of intravascular staining to define innate and adaptive immune cells in mice.
Wed Jan 01 00:00:00 EST 2014
T helper cell IL-4 drives intestinal Th2 priming to oral peanut antigen, under the control of OX40L and independent of innate-like lymphocytes.
Mucosal immunology
Chu DK,Mohammed-Ali Z,Jiménez-Saiz R,Walker TD,Goncharova S,Llop-Guevara A,Kong J,Gordon ME,Barra NG,Gillgrass AE,Van Seggelen H,Khan WI,Ashkar AA,Bramson JL,Humbles AA,Kolbeck R,Waserman S,Jordana M
47-0902 was used in Flow cytometry/Cell sorting to reveal intestinal Th2 priming is initiated by an autocrine/paracrine acting CD4(+) Th cell-intrinsic IL-4 program that is controlled by DC OX40L.
Sat Nov 01 00:00:00 EDT 2014
Type 2 innate lymphoid cells control eosinophil homeostasis.
Nature
Nussbaum JC,Van Dyken SJ,von Moltke J,Cheng LE,Mohapatra A,Molofsky AB,Thornton EE,Krummel MF,Chawla A,Liang HE,Locksley RM
47-0902 was used in Flow cytometry/Cell sorting to investigate the processes underlying regulation of cytokine and chemokines for eosinophil development and survival, showing that type 2 innate lymphoid cells control eosinophil homeostasis.
Thu Oct 10 00:00:00 EDT 2013
PD-L1/B7-H1 regulates the survival but not the function of CD8+ T cells in herpes simplex virus type 1 latently infected trigeminal ganglia.
Journal of immunology (Baltimore, Md. : 1950)
Jeon S,St Leger AJ,Cherpes TL,Sheridan BS,Hendricks RL
47-0902 was used in Flow cytometry/Cell sorting to investigate the role of PD-L1/B7-H1 in herpes simplex virus type 1 infection, showing it regulates survival but not the function of CD8+ T cells.
Sat Jun 15 00:00:00 EDT 2013
Partial characterization of the Sox2+ cell population in an adult murine model of digit amputation.
Tissue engineering. Part A
Agrawal V,Siu BF,Chao H,Hirschi KK,Raborn E,Johnson SA,Tottey S,Hurley KB,Medberry CJ,Badylak SF
Published figure using CD90.2 (Thy-1.2) monoclonal antibody (Product # 47-0902-82) in Flow Cytometry
Sun Jul 01 00:00:00 EDT 2012
Nuclear export of the NF-κB inhibitor IκBα is required for proper B cell and secondary lymphoid tissue formation.
Immunity
Wuerzberger-Davis SM,Chen Y,Yang DT,Kearns JD,Bates PW,Lynch C,Ladell NC,Yu M,Podd A,Zeng H,Huang TT,Wen R,Hoffmann A,Wang D,Miyamoto S
Published figure using CD90.2 (Thy-1.2) monoclonal antibody (Product # 47-0902-82) in Flow Cytometry
Fri Feb 25 00:00:00 EST 2011
A critical role of TAK1 in B-cell receptor-mediated nuclear factor kappaB activation.
Blood
Schuman J,Chen Y,Podd A,Yu M,Liu HH,Wen R,Chen ZJ,Wang D
Published figure using CD90.2 (Thy-1.2) monoclonal antibody (Product # 47-0902-82) in Flow Cytometry
Thu May 07 00:00:00 EDT 2009
Tracking epitope-specific T cells.
Nature protocols
Moon JJ,Chu HH,Hataye J,Pagán AJ,Pepper M,McLachlan JB,Zell T,Jenkins MK
Published figure using CD90.2 (Thy-1.2) monoclonal antibody (Product # 47-0902-82) in Flow Cytometry
Tue Jun 30 00:00:00 EDT 2009
Manganese superoxide dismutase gene dosage affects chromosomal instability and tumor onset in a mouse model of T cell lymphoma.
Free radical biology & medicine
van de Wetering CI,Coleman MC,Spitz DR,Smith BJ,Knudson CM
Published figure using CD90.2 (Thy-1.2) monoclonal antibody (Product # 47-0902-82) in Flow Cytometry
Tue Apr 15 00:00:00 EDT 2008