Product References
XiaoEr LianHuaQinqGan alleviates viral pneumonia in mice infected by influenza A and respiratory syncytial viruses.
Pharmaceutical biology
Li W,Li T,Zhao C,Song T,Mi Y,Chuangfeng Z,Hou Y,Jia Z
MF48004-3 was used in Flow cytometry/Cell sorting to demonstrate pharmacological effects of XELH against viral pneumonia: it inhibits pro-inflammatory cytokines, viral replication and load.
Thu Dec 01 00:00:00 EST 2022
Myeloid DJ-1 deficiency protects acetaminophen-induced acute liver injury through decreasing inflammatory response.
Aging
Wang B,Li J,Jiao J,Xu M,Luo Y,Wang F,Xia Q,Gao Y,Feng Y,Kong X,Sun X
MF48004-3 was used in Flow Cytometry to suggest DJ-1 as a potential therapeutic and/or prophylactic target of APAP-induced acute liver injury.
Wed Jul 21 00:00:00 EDT 2021
Ly6G+ inflammatory cells enable the conversion of cancer cells to cancer stem cells in an irradiated glioblastoma model.
Cell death and differentiation
Jeon HY,Ham SW,Kim JK,Jin X,Lee SY,Shin YJ,Choi CY,Sa JK,Kim SH,Chun T,Jin X,Nam DH,Kim H
MF48004 was used in Flow cytometry/Cell sorting to demonstrate that radiation-induced senescent glioblastoma cells exhibit a senescence-associated secretory phenotype that functions through NFκB signalling to influence changes in the tumour microenvironment.
Tue Oct 01 00:00:00 EDT 2019
Inflammation induced by incomplete radiofrequency ablation accelerates tumor progression and hinders PD-1 immunotherapy.
Nature communications
Shi L,Wang J,Ding N,Zhang Y,Zhu Y,Dong S,Wang X,Peng C,Zhou C,Zhou L,Li X,Shi H,Wu W,Long X,Wu C,Liao W
Published figure using F4/80 monoclonal antibody (Product # MF48004) in Flow Cytometry
Thu Nov 28 00:00:00 EST 2019
Phc2 controls hematopoietic stem and progenitor cell mobilization from bone marrow by repressing Vcam1 expression.
Nature communications
Bae J,Choi SP,Isono K,Lee JY,Park SW,Choi CY,Han J,Kim SH,Lee HH,Park K,Jin HY,Lee SJ,Park CG,Koseki H,Lee YS,Chun T
MF48004 was used in Flow cytometry/Cell sorting to determine the role of PHc2 in controlling the mobilisation of hematopoietic stem and progenitor cells.
Fri Aug 02 00:00:00 EDT 2019
In Atp7b Mice Modeling Wilson's Disease Liver Repopulation With Bone Marrow-Derived Myofibroblasts or Inflammatory Cells and Not Hepatocytes Is Deleterious.
Gene expression
Sharma Y,Liu J,Kristian KE,Follenzi A,Gupta S
MF48004 was used in Immunohistochemistry-immunofluorescence to study the therapeutic potential of stem cells in Wilson's disease.
Fri Dec 14 00:00:00 EST 2018
Macrophage-derived IL-10 mediates mucosal repair by epithelial WISP-1 signaling.
The Journal of clinical investigation
Quiros M,Nishio H,Neumann PA,Siuda D,Brazil JC,Azcutia V,Hilgarth R,O'Leary MN,Garcia-Hernandez V,Leoni G,Feng M,Bernal G,Williams H,Dedhia PH,Gerner-Smidt C,Spence J,Parkos CA,Denning TL,Nusrat A
MF48004 was used in Flow cytometry/Cell sorting to investigate the mechanisms involved in crosstalk between immune cells and the epithelium in mucosal barrier repair.
Fri Sep 01 00:00:00 EDT 2017
Macrophage-derived IL-10 mediates mucosal repair by epithelial WISP-1 signaling.
The Journal of clinical investigation
Quiros M,Nishio H,Neumann PA,Siuda D,Brazil JC,Azcutia V,Hilgarth R,O'Leary MN,Garcia-Hernandez V,Leoni G,Feng M,Bernal G,Williams H,Dedhia PH,Gerner-Smidt C,Spence J,Parkos CA,Denning TL,Nusrat A
MF48004 was used in Flow cytometry/Cell sorting to investigate the mechanisms involved in crosstalk between immune cells and the epithelium in mucosal barrier repair.
Fri Sep 01 00:00:00 EDT 2017
Mitochondrial respiratory-chain adaptations in macrophages contribute to antibacterial host defense.
Nature immunology
Garaude J,Acín-Pérez R,Martínez-Cano S,Enamorado M,Ugolini M,Nistal-Villán E,Hervás-Stubbs S,Pelegrín P,Sander LE,Enríquez JA,Sancho D
MF48004 was used in flow cytometry to explore how bacterial infections alter the mitochondrial electron-transport chain in macrophages
Thu Sep 01 00:00:00 EDT 2016
The RNA-binding protein TTP is a global post-transcriptional regulator of feedback control in inflammation.
Nucleic acids research
Tiedje C,Diaz-Muñoz MD,Trulley P,Ahlfors H,Laaß K,Blackshear PJ,Turner M,Gaestel M
MF48004 was used in Flow cytometry/Cell sorting to uncover a role of TTP as a suppressor of feedback inhibitors of inflammation and highlight the importance of TTP activity-regulation by MK2 to control the pro-inflammatory response.
Tue Sep 06 00:00:00 EDT 2016
Autophagy induced by AXL receptor tyrosine kinase alleviates acute liver injury via inhibition of NLRP3 inflammasome activation in mice.
Autophagy
Han J,Bae J,Choi CY,Choi SP,Kang HS,Jo EK,Park J,Lee YS,Moon HS,Park CG,Lee MS,Chun T
MF48004 was used in immunohistochemistry - paraffin section to assess the role of individual TAM family proteins during autophagy induction and hepatic inflammation
Thu Dec 01 00:00:00 EST 2016
E2f3 in tumor macrophages promotes lung metastasis.
Oncogene
Trikha P,Sharma N,Pena C,Reyes A,Pécot T,Khurshid S,Rawahneh M,Moffitt J,Stephens JA,Fernandez SA,Ostrowski MC,Leone G
MF48004 was used in immunohistochemistry - paraffin section to learn how promotion of lung metastasis occurs by E2f3 in tumor macrophages
Thu Jul 14 00:00:00 EDT 2016
The expression of mouse CLEC-2 on leucocyte subsets varies according to their anatomical location and inflammatory state.
European journal of immunology
Lowe KL,Navarro-Núñez L,Bénézech C,Nayar S,Kingston BL,Nieswandt B,Barone F,Watson SP,Buckley CD,Desanti GE
MF48004 was used in flow cytometry to assess surface expression of C-type lectin-like receptor 2 on hematopoietic cells from peripheral blood and secondary lymphoid organs
Tue Sep 01 00:00:00 EDT 2015
Antibody-mediated phagocytosis contributes to the anti-tumor activity of the therapeutic antibody daratumumab in lymphoma and multiple myeloma.
mAbs
Overdijk MB,Verploegen S,Bögels M,van Egmond M,Lammerts van Bueren JJ,Mutis T,Groen RW,Breij E,Martens AC,Bleeker WK,Parren PW
MF48004 was used in flow cytometry to test if macrophages contribute to the effect of daratumumab treatment.
Mon Nov 30 00:00:00 EST 2015
BMP pathway regulation of and by macrophages.
PloS one
Talati M,West J,Zaynagetdinov R,Hong CC,Han W,Blackwell T,Robinson L,Blackwell TS,Lane K
MF48004 was used in Flow cytometry/Cell sorting to investigate the impact of BMPR2 mutations on SMAD signalling.
Tue Jan 06 00:00:00 EST 2015
The ShcA PTB domain functions as a biological sensor of phosphotyrosine signaling during breast cancer progression.
Cancer research
Ahn R,Sabourin V,Ha JR,Cory S,Maric G,Im YK,Hardy WR,Zhao H,Park M,Hallett M,Siegel PM,Pawson T,Ursini-Siegel J
MF48004-3 was used in immunohistochemistry to investigate the role of ShcA PTB domain in phosphotyrosine signaling during breast cancer progression
Mon Jul 15 00:00:00 EDT 2013
Dendritic cell-specific ablation of the protein tyrosine phosphatase Shp1 promotes Th1 cell differentiation and induces autoimmunity.
Journal of immunology (Baltimore, Md. : 1950)
Kaneko T,Saito Y,Kotani T,Okazawa H,Iwamura H,Sato-Hashimoto M,Kanazawa Y,Takahashi S,Hiromura K,Kusakari S,Kaneko Y,Murata Y,Ohnishi H,Nojima Y,Takagishi K,Matozaki T
MF48004 was used in flow cytometry to report that Shp1 regulates DC functions and prevents autoimmunity.
Fri Jun 01 00:00:00 EDT 2012
YBX1 expression and function in early hematopoiesis and leukemic cells.
Immunogenetics
Bhullar J,Sollars VE
MF48004 was used in flow cytometry to investigate the role of Y-box protein during early hematopoietic differentiation and leukemia.
Wed Jun 01 00:00:00 EDT 2011
A high omega-3 fatty acid diet has different effects on early and late stage myeloid progenitors.
Lipids
Varney ME,Buchanan JT,Dementieva Y,Hardman WE,Sollars VE
MF48004 was used in flow cytometry to investigate the effects of high n-3 FA diets on early stages of myelopoiesis
Sat Jan 01 00:00:00 EST 2011
Acquisition of the contractile phenotype by murine arterial smooth muscle cells depends on the Mir143/145 gene cluster.
The Journal of clinical investigation
Boettger T,Beetz N,Kostin S,Schneider J,Krüger M,Hein L,Braun T
MF48004 was used in Western Blotting to demonstrate that the mouse miR-143/145 cluster, is required for vascular smooth muscle cell acquisition of the contractile phenotype.
Tue Sep 01 00:00:00 EDT 2009
Lymphocytes in the peritoneum home to the omentum and are activated by resident dendritic cells.
Journal of immunology (Baltimore, Md. : 1950)
Carlow DA,Gold MR,Ziltener HJ
MF48004 was used in flow cytometry to investigate how lymphocytes traffic between the peritoneal cavity and omentum
Wed Jul 15 00:00:00 EDT 2009
The influence of mating on estrogen receptor alpha protein level in spleen and uterine macrophages in female mice.
Reproductive biology
Piesta A,Maj T,Chełmońska-Soyta A
MF48004 was used in flow cytometry to assess changes in the estrogen receptor alpha protein in macrophages during the preimplantation period
Sun Nov 01 00:00:00 EDT 2009
Murine norovirus: an intercurrent variable in a mouse model of bacteria-induced inflammatory bowel disease.
Comparative medicine
Lencioni KC,Seamons A,Treuting PM,Maggio-Price L,Brabb T
MF48004 was used in Flow cytometry/Cell sorting to indicate that acute MNV4 infection is immunomodulatory and alters disease progression in a mouse model of inflammatory bowl disease.
Mon Dec 01 00:00:00 EST 2008
Role for CTLA-4 but not CD25+ T cells during Schistosoma mansoni infection of mice.
Parasite immunology
Walsh CM,Smith P,Fallon PG
MF48004 was used in flow cytometry to study the regulation of CTLA-4+ and CD25+ T cells in schistosome infection
Fri Jun 01 00:00:00 EDT 2007
Helminth-modified pulmonary immune response protects mice from allergen-induced airway hyperresponsiveness.
Journal of immunology (Baltimore, Md. : 1950)
Mangan NE,van Rooijen N,McKenzie AN,Fallon PG
MF48004 was used in flow cytometry to elucidate the mechanisms that regulate the inverse relationship between helminth infections and allergies
Sun Jan 01 00:00:00 EST 2006
Effect of thermal injury on splenic myelopoiesis.
Shock (Augusta, Ga.)
Noel JG,Guo X,Wells-Byrum D,Schwemberger S,Caldwell CC,Ogle CK
MF48004 was used in flow cytometry to measure the number of splenic myeloid progenitors and their progeny after burn injury
Tue Feb 01 00:00:00 EST 2005
Schistosoma mansoni worms induce anergy of T cells via selective up-regulation of programmed death ligand 1 on macrophages.
Journal of immunology (Baltimore, Md. : 1950)
Smith P,Walsh CM,Mangan NE,Fallon RE,Sayers JR,McKenzie AN,Fallon PG
MF48004 was used in flow cytometry to elucidate how Schistosoma mansoni suppresses T cell activation
Thu Jul 15 00:00:00 EDT 2004
A peptide derived from bovine beta-casein modulates functional properties of bone marrow-derived macrophages from germfree and human flora-associated mice.
The Journal of nutrition
Sandré C,Gleizes A,Forestier F,Gorges-Kergot R,Chilmonczyk S,Léonil J,Moreau MC,Labarre C
MF48004 was used in flow cytometry to report that beta-CN peptide enhances antimicrobial activity of macrophages without proinflammatory effects.
Thu Nov 01 00:00:00 EST 2001
