Product References
Fasudil-modified macrophages reduce inflammation and regulate the immune response in experimental autoimmune encephalomyelitis.
Neural regeneration research
Liu C,Guo S,Liu R,Guo M,Wang Q,Chai Z,Xiao B,Ma C
Published figure using IFN gamma monoclonal antibody (Product # 45-7311-82) in Flow Cytometry
Fri Mar 01 00:00:00 EST 2024
T cell-derived interleukin-22 drives the expression of CD155 by cancer cells to suppress NK cell function and promote metastasis.
Immunity
Briukhovetska D,Suarez-Gosalvez J,Voigt C,Markota A,Giannou AD,Schübel M,Jobst J,Zhang T,Dörr J,Märkl F,Majed L,Müller PJ,May P,Gottschlich A,Tokarew N,Lücke J,Oner A,Schwerdtfeger M,Andreu-Sanz D,Grünmeier R,Seifert M,Michaelides S,Hristov M,König LM,Cadilha BL,Mikhaylov O,Anders HJ,Rothenfusser S,Flavell RA,Cerezo-Wallis D,Tejedo C,Soengas MS,Bald T,Huber S,Endres S,Kobold S
Published figure using IFN gamma monoclonal antibody (Product # 45-7311-82) in Flow Cytometry
Tue Jan 10 00:00:00 EST 2023
Biometabolites of Citrus unshiu Peel Enhance Intestinal Permeability and Alter Gut Commensal Bacteria.
Nutrients
Lee SH,Seo D,Lee KH,Park SJ,Park S,Kim H,Kim T,Joo IH,Park JM,Kang YH,Lim GH,Kim DH,Yang JY
Published figure using IFN gamma monoclonal antibody (Product # 45-7311-82) in Flow Cytometry
Mon Jan 09 00:00:00 EST 2023
Spleen-targeted neoantigen DNA vaccine for personalized immunotherapy of hepatocellular carcinoma.
EMBO molecular medicine
Wu M,Luo Z,Cai Z,Mao Q,Li Z,Li H,Zhang C,Zhang Y,Zhong A,Wu L,Liu X
Published figure using IFN gamma monoclonal antibody (Product # 45-7311-82) in Flow Cytometry
Wed Oct 11 00:00:00 EDT 2023
Alleviating psoriatic skin inflammation through augmentation of Treg cells via CTLA-4 signaling peptide.
Frontiers in immunology
Lee WS,Nam KH,Kim JH,Kim WJ,Kim JE,Shin EC,Kim GR,Choi JM
Published figure using IFN gamma monoclonal antibody (Product # 45-7311-82) in Flow Cytometry
Thu Oct 12 00:00:00 EDT 2023
Klebsiella pneumoniae Induces Inflammatory Bowel Disease Through Caspase-11-Mediated IL18 in the Gut Epithelial Cells.
Cellular and molecular gastroenterology and hepatology
Zhang Q,Su X,Zhang C,Chen W,Wang Y,Yang X,Liu D,Zhang Y,Yang R
Published figure using IFN gamma monoclonal antibody (Product # 45-7311-82) in Flow Cytometry
Thu Feb 23 00:00:00 EST 2023
Respiratory mucosal vaccination of peptide-poloxamine-DNA nanoparticles provides complete protection against lethal SARS-CoV-2 challenge.
Biomaterials
Sun S,Li E,Zhao G,Tang J,Zuo Q,Cai L,Xu C,Sui C,Ou Y,Liu C,Li H,Ding Y,Li C,Lu D,Zhang W,Luo P,Cheng P,Gao Y,Tu C,Pitard B,Rosenecker J,Wang B,Liu Y,Zou Q,Guan S
Published figure using IFN gamma monoclonal antibody (Product # 45-7311-82) in Flow Cytometry
Sun Jan 01 00:00:00 EST 2023
Murine cytomegalovirus downregulates ERAAP and induces an unconventional T cell response to self.
Cell reports
Geiger KM,Manoharan M,Coombs R,Arana K,Park CS,Lee AY,Shastri N,Robey EA,Coscoy L
Published figure using IFN gamma monoclonal antibody (Product # 45-7311-82) in Flow Cytometry
Tue Apr 25 00:00:00 EDT 2023
Differential requirement of neutralizing antibodies and T cells on protective immunity to SARS-CoV-2 variants of concern.
NPJ vaccines
Azevedo PO,Hojo-Souza NS,Faustino LP,Fumagalli MJ,Hirako IC,Oliveira ER,Figueiredo MM,Carvalho AF,Doro D,Benevides L,Durigon E,Fonseca F,Machado AM,Fernandes AP,Teixeira SR,Silva JS,Gazzinelli RT
45-7311-82 was used in Flow cytometry/Cell sorting to evaluate the efficacy of a Spike-based DNA vaccine (pCTV-WS) for protection against different VOCs using existing pre-clinical models of severe and moderate COVID-19.
Mon Feb 13 00:00:00 EST 2023
Self-amplifying mRNA seasonal influenza vaccines elicit mouse neutralizing antibody and cell-mediated immunity and protect ferrets.
NPJ vaccines
Cheung M,Chang C,Rathnasinghe R,Rossignol E,Zhang Y,Ferrari A,Patel H,Huang Y,Sanchez Guillen M,Scalzo T,Lee C,Otten GR,Settembre EC,Music N,Palladino G,Wen Y
45-7311-82 was used in Flow Cytometry to demonstrate that next-generation bicistronic sa-mRNA vaccines expressing HA and NA induce potent antibodies against both viral coat proteins, as well as vaccine-specific cell-mediated immunity.
Wed Oct 04 00:00:00 EDT 2023
IL-18BP mediates the balance between protective and pathological immune responses to Toxoplasma gondii.
Cell reports
Clark JT,Weizman OE,Aldridge DL,Shallberg LA,Eberhard J,Lanzar Z,Wasche D,Huck JD,Zhou T,Ring AM,Hunter CA
45-7311-82 was used in Flow cytometry/Cell sorting to investigate the role of interleukin-18 (IL-18) and its binding protein (IL-18BP) in controlling Toxoplasma gondii infection.
Tue Mar 28 00:00:00 EDT 2023
TCR repertoire landscape reveals macrophage-mediated clone deletion in endotoxin tolerance.
Inflammation research : official journal of the European Histamine Research Society ... [et al.]
Zhao J,Jia L,Tao Y,Zhao X,Yang J,Lu Y,Yan Y,Mao L,Hu L,Lu J,Guo M,Chen C,Zhou Y,Wen Z,He Z,Xu L
45-7311-82 was used in Flow cytometry/Cell sorting to suggest that the clone selection in thymus in Endotoxin tolerance may confer protection against microbial sepsis.
Wed Mar 01 00:00:00 EST 2023
Histone methyltransferase WHSC1 loss dampens MHC-I antigen presentation pathway to impair IFN-γ-stimulated antitumor immunity.
The Journal of clinical investigation
Ren J,Li N,Pei S,Lian Y,Li L,Peng Y,Liu Q,Guo J,Wang X,Han Y,Zhang G,Wang H,Li Y,Jiang J,Li Q,Tan M,Peng J,Hu G,Xiao Y,Li X,Lin M,Qin J
Published figure using IFN gamma monoclonal antibody (Product # 45-7311-82) in Flow Cytometry
Fri Apr 15 00:00:00 EDT 2022
A peptide encoded by pri-miRNA-31 represses autoimmunity by promoting Treg differentiation.
EMBO reports
Zhou H,Lou F,Bai J,Sun Y,Cai W,Sun L,Xu Z,Liu Z,Zhang L,Yin Q,Zhang J,Gao Y,Wang Z,Niu L,Cai X,Deng S,Wang H,Xia L,Ginhoux F,Li Q,Wang H
Published figure using IFN gamma monoclonal antibody (Product # 45-7311-82) in Flow Cytometry
Wed May 04 00:00:00 EDT 2022
Penfluridol targets acid sphingomyelinase to inhibit TNF signaling and is therapeutic against inflammatory autoimmune diseases.
Arthritis research & therapy
Chen YH,Liu RH,Cui YZ,Hettinghouse A,Fu WY,Zhang L,Zhang C,Liu CJ
Published figure using IFN gamma monoclonal antibody (Product # 45-7311-82) in Flow Cytometry
Wed Jan 19 00:00:00 EST 2022
Penfluridol targets acid sphingomyelinase to inhibit TNF signaling and is therapeutic against inflammatory autoimmune diseases.
Arthritis research & therapy
Chen YH,Liu RH,Cui YZ,Hettinghouse A,Fu WY,Zhang L,Zhang C,Liu CJ
Published figure using IFN gamma monoclonal antibody (Product # 45-7311-82) in Flow Cytometry
Wed Jan 19 00:00:00 EST 2022
Neutrophil extracellular traps and their histones promote Th17 cell differentiation directly via TLR2.
Nature communications
Wilson AS,Randall KL,Pettitt JA,Ellyard JI,Blumenthal A,Enders A,Quah BJ,Bopp T,Parish CR,Brüstle A
Published figure using IFN gamma monoclonal antibody (Product # 45-7311-82) in Flow Cytometry
Wed Jan 26 00:00:00 EST 2022
Forsythiaside A Improves the Inhibitory Efficiency of Recombinant Protein Vaccines against Bovine Viral Diarrhea Virus Infection.
International journal of molecular sciences
Yang G,Wang J,Wang S,Zhu Y
Published figure using IFN gamma monoclonal antibody (Product # 45-7311-82) in Flow Cytometry
Sat Aug 20 00:00:00 EDT 2022
Dendritic cell Piezo1 directs the differentiation of TH1 and Treg cells in cancer.
eLife
Wang Y,Yang H,Jia A,Wang Y,Yang Q,Dong Y,Hou Y,Cao Y,Dong L,Bi Y,Liu G
Published figure using IFN gamma monoclonal antibody (Product # 45-7311-82) in Flow Cytometry
Mon Aug 22 00:00:00 EDT 2022
Leishmania donovani Impedes Antileishmanial Immunity by Suppressing Dendritic Cells via the TIM-3 Receptor.
mBio
Akhtar MN,Kumar S,Sen P
Published figure using IFN gamma monoclonal antibody (Product # 45-7311-82) in Flow Cytometry
Tue Aug 30 00:00:00 EDT 2022
Agr2-associated ER stress promotes adherent-invasive E. coli dysbiosis and triggers CD103+ dendritic cell IL-23-dependent ileocolitis.
Cell reports
Viladomiu M,Khounlotham M,Dogan B,Lima SF,Elsaadi A,Cardakli E,Castellanos JG,Ng C,Herzog J,Schoenborn AA,Ellermann M,Liu B,Zhang S,Gulati AS,Sartor RB,Simpson KW,Lipkin SM,Longman RS
Published figure using IFN gamma monoclonal antibody (Product # 45-7311-82) in Flow Cytometry
Tue Nov 15 00:00:00 EST 2022
Lin28B-high breast cancer cells promote immune suppression in the lung pre-metastatic niche via exosomes and support cancer progression.
Nature communications
Qi M,Xia Y,Wu Y,Zhang Z,Wang X,Lu L,Dai C,Song Y,Xu K,Ji W,Zhan L
Published figure using IFN gamma monoclonal antibody (Product # 45-7311-82) in Flow Cytometry
Wed Feb 16 00:00:00 EST 2022
Breast cancer cell-derived extracellular vesicles promote CD8+ T cell exhaustion via TGF-β type II receptor signaling.
Nature communications
Xie F,Zhou X,Su P,Li H,Tu Y,Du J,Pan C,Wei X,Zheng M,Jin K,Miao L,Wang C,Meng X,van Dam H,Ten Dijke P,Zhang L,Zhou F
Published figure using IFN gamma monoclonal antibody (Product # 45-7311-82) in Flow Cytometry
Mon Aug 01 00:00:00 EDT 2022
Local and Systemic Injections of Human Cord Blood Myeloid-Derived Suppressor Cells to Prevent Graft Rejection in Corneal Transplantation.
Biomedicines
Lee JY,Sohn HJ,Kim CH,Kim TG,Lee HS
Published figure using IFN gamma monoclonal antibody (Product # 45-7311-82) in Flow Cytometry
Mon Dec 12 00:00:00 EST 2022
Transcription factor RORα enforces stability of the Th17 cell effector program by binding to a Rorc cis-regulatory element.
Immunity
Hall JA,Pokrovskii M,Kroehling L,Kim BR,Kim SY,Wu L,Lee JY,Littman DR
Published figure using IFN gamma monoclonal antibody (Product # 45-7311-82) in Flow Cytometry
Tue Nov 08 00:00:00 EST 2022
Meningeal lymphatic drainage promotes T cell responses against Toxoplasma gondii but is dispensable for parasite control in the brain.
eLife
Kovacs MA,Cowan MN,Babcock IW,Sibley LA,Still K,Batista SJ,Labuzan SA,Sethi I,Harris TH
45-7311-82 was used in Flow cytometry/Cell sorting to reveal that CNS lymphatic drainage supports the development of peripheral T cell responses against T. gondii but remains dispensable for immune protection of the brain.
Wed Dec 21 00:00:00 EST 2022
Nicotinamide breaks effector CD8 T cell responses by targeting mTOR signaling.
iScience
Agliano F,Karginov TA,Ménoret A,Provatas A,Vella AT
45-7311-82 was used in Flow Cytometry to identify Nicotinamide as a potential therapeutic supplement that uncouples glycolysis from effector cytokine production and may be a powerful treatment for diseases associated with T cell hyperactivation.
Fri Mar 18 00:00:00 EDT 2022
Lactate induces metabolic and epigenetic reprogramming of pro-inflammatory Th17 cells.
EMBO reports
Lopez Krol A,Nehring HP,Krause FF,Wempe A,Raifer H,Nist A,Stiewe T,Bertrams W,Schmeck B,Luu M,Leister H,Chung HR,Bauer UM,Adhikary T,Visekruna A
Published figure using IFN gamma monoclonal antibody (Product # 45-7311-82) in Flow Cytometry
Tue Dec 06 00:00:00 EST 2022
RhoB affects colitis through modulating cell signaling and intestinal microbiome.
Microbiome
Yang J,Pei G,Sun X,Xiao Y,Miao C,Zhou L,Wang B,Yang L,Yu M,Zhang ZS,Keller ET,Yao Z,Wang Q
45-7311-82 was used in Flow cytometry/Cell sorting to study the potential role of RhoB as a biomarker for colitis by studying the colon tissues of ulcerative colitis (UC) patients and mice with DSS-induced colitis.
Fri Sep 16 00:00:00 EDT 2022
Expansion of T memory stem cells with superior anti-tumor immunity by Urolithin A-induced mitophagy.
Immunity
Denk D,Petrocelli V,Conche C,Drachsler M,Ziegler PK,Braun A,Kress A,Nicolas AM,Mohs K,Becker C,Neurath MF,Farin HF,Buchholz CJ,Andreux PA,Rinsch C,Greten FR
45-7311-82 was used in Sample Preparation to unravel a critical signaling pathway linking mitophagy to T memory stem cell formation and suggest that the metabolic compound Urolithin A represents an option to improve immune therapy.
Tue Nov 08 00:00:00 EST 2022
RAGE-mediated T cell metabolic reprogramming shapes T cell inflammatory response after stroke.
Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism
Zhang Y,Li F,Chen C,Li Y,Xie W,Huang D,Zhai X,Yu W,Wan J,Li P
45-7311-82 was used in Flow cytometry/Cell sorting to show that sRAGE can serve as a novel immunometabolic modulator that ameliorates ischemic stroke recovery by inhibiting fatty acid synthesis and thus favoring CD4+ T cells polarization toward Treg after cerebral ischemia injury.
Wed Jun 01 00:00:00 EDT 2022
Endogenous retroviruses promote homeostatic and inflammatory responses to the microbiota.
Cell
Lima-Junior DS,Krishnamurthy SR,Bouladoux N,Collins N,Han SJ,Chen EY,Constantinides MG,Link VM,Lim AI,Enamorado M,Cataisson C,Gil L,Rao I,Farley TK,Koroleva G,Attig J,Yuspa SH,Fischbach MA,Kassiotis G,Belkaid Y
Published figure using IFN gamma monoclonal antibody (Product # 45-7311-82) in Flow Cytometry
Thu Jul 08 00:00:00 EDT 2021
The CD94/NKG2A inhibitory receptor educates uterine NK cells to optimize pregnancy outcomes in humans and mice.
Immunity
Shreeve N,Depierreux D,Hawkes D,Traherne JA,Sovio U,Huhn O,Jayaraman J,Horowitz A,Ghadially H,Perry JRB,Moffett A,Sled JG,Sharkey AM,Colucci F
Published figure using IFN gamma monoclonal antibody (Product # 45-7311-82) in Flow Cytometry
Tue Jun 08 00:00:00 EDT 2021
The deubiquitinase OTUB1 augments NF-κB-dependent immune responses in dendritic cells in infection and inflammation by stabilizing UBC13.
Cellular & molecular immunology
Mulas F,Wang X,Song S,Nishanth G,Yi W,Brunn A,Larsen PK,Isermann B,Kalinke U,Barragan A,Naumann M,Deckert M,Schlüter D
Published figure using IFN gamma monoclonal antibody (Product # 45-7311-82) in Flow Cytometry
Tue Jun 01 00:00:00 EDT 2021
AIM2 controls microglial inflammation to prevent experimental autoimmune encephalomyelitis.
The Journal of experimental medicine
Ma C,Li S,Hu Y,Ma Y,Wu Y,Wu C,Liu X,Wang B,Hu G,Zhou J,Yang S
Published figure using IFN gamma monoclonal antibody (Product # 45-7311-82) in Flow Cytometry
Mon May 03 00:00:00 EDT 2021
Mapping and role of T cell response in SARS-CoV-2-infected mice.
The Journal of experimental medicine
Zhuang Z,Lai X,Sun J,Chen Z,Zhang Z,Dai J,Liu D,Li Y,Li F,Wang Y,Zhu A,Wang J,Yang W,Huang J,Li X,Hu L,Wen L,Zhuo J,Zhang Y,Chen D,Li S,Huang S,Shi Y,Zheng K,Zhong N,Zhao J,Zhou D,Zhao J
Published figure using IFN gamma monoclonal antibody (Product # 45-7311-82) in Flow Cytometry
Mon Apr 05 00:00:00 EDT 2021
Low immunogenicity of malaria pre-erythrocytic stages can be overcome by vaccination.
EMBO molecular medicine
Müller K,Gibbins MP,Roberts M,Reyes-Sandoval A,Hill AVS,Draper SJ,Matuschewski K,Silvie O,Hafalla JCR
Published figure using IFN gamma monoclonal antibody (Product # 45-7311-82) in Flow Cytometry
Fri Apr 09 00:00:00 EDT 2021
Multifaceted modes of action of the anticancer probiotic Enterococcus hirae.
Cell death and differentiation
Goubet AG,Wheeler R,Fluckiger A,Qu B,Lemaître F,Iribarren K,Mondragón L,Tidjani Alou M,Pizzato E,Durand S,Derosa L,Aprahamian F,Bossut N,Moya-Nilges M,Derrien D,Chen G,Leduc M,Joseph A,Pons N,Le Chatelier E,Segata N,Yonekura S,Iebba V,Kepp O,Raoult D,André F,Kroemer G,Boneca IG,Zitvogel L,Daillère R
45-7311-82 was used in Flow cytometry/Cell sorting to surmise that immunological, metabolic, epithelial, and microbial modes of action of the live E. hirae cooperate to circumvent primary resistance to therapy.
Thu Jul 01 00:00:00 EDT 2021
High Ambient Temperature Aggravates Experimental Autoimmune Uveitis Symptoms.
Frontiers in cell and developmental biology
Pan S,Tan H,Chang R,Wang Q,Zhu Y,Chen L,Li H,Su G,Zhou C,Cao Q,Kijlstra A,Yang P
Published figure using IFN gamma monoclonal antibody (Product # 45-7311-82) in Flow Cytometry
Tue Apr 13 00:00:00 EDT 2021
Senescent T Cell Induces Brown Adipose Tissue "Whitening" Via Secreting IFN-γ.
Frontiers in cell and developmental biology
Pan XX,Yao KL,Yang YF,Ge Q,Zhang R,Gao PJ,Ruan CC,Wu F
Published figure using IFN gamma monoclonal antibody (Product # 45-7311-82) in Flow Cytometry
Tue Mar 23 00:00:00 EDT 2021
Trichinella spiralis Paramyosin Induces Colonic Regulatory T Cells to Mitigate Inflammatory Bowel Disease.
Frontiers in cell and developmental biology
Hao C,Wang W,Zhan B,Wang Z,Huang J,Sun X,Zhu X
Published figure using IFN gamma monoclonal antibody (Product # 45-7311-82) in Flow Cytometry
Tue Aug 03 00:00:00 EDT 2021
Prevention of EAE by tolerogenic vaccination with PEGylated antigenic peptides.
Therapeutic advances in chronic disease
Pfeil J,Simonetti M,Lauer U,von Thülen B,Durek P,Poulsen C,Pawlowska J,Kröger M,Krähmer R,Leenders F,Hoffmann U,Hamann A
Published figure using IFN gamma monoclonal antibody (Product # 45-7311-82) in Flow Cytometry
Tue Nov 07 00:00:00 EST 2023
Generation of a Novel Oncolytic Vaccinia Virus Using the IHD-W Strain.
Human gene therapy
Shin J,Hong SO,Kim M,Lee H,Choi H,Kim J,Hong J,Kang H,Lee E,Lee S,Kong B,Kim M,Choi H,Kim S
Published figure using IFN gamma monoclonal antibody (Product # 45-7311-82) in Flow Cytometry
Sat May 01 00:00:00 EDT 2021
Identification of CTL Epitopes on Efflux Pumps of the ATP-Binding Cassette and the Major Facilitator Superfamily of Mycobacterium tuberculosis.
Journal of immunology research
Lin Y,Dong Y,Gao Y,Shi R,Li Y,Zhou X,Liu W,Li G,Qi Y,Wu Y
Published figure using IFN gamma monoclonal antibody (Product # 45-7311-82) in Flow Cytometry
Mon Sep 20 00:00:00 EDT 2021
Fine particulate matter induces airway inflammation by disturbing the balance between Th1/Th2 and regulation of GATA3 and Runx3 expression in BALB/c mice.
Molecular medicine reports
Pang L,Yu P,Liu X,Fan Y,Shi Y,Zou S
Published figure using IFN gamma monoclonal antibody (Product # 45-7311-82) in Flow Cytometry
Sat May 01 00:00:00 EDT 2021
Irradiated whole-cell vaccine suppresses hepatocellular carcinoma growth in mice via Th9 cells.
Oncology letters
Chen J,Ding Y,Huang F,Lan R,Wang Z,Huang W,Chen R,Wu B,Fu L,Yang Y,Liu J,Hong J,Zhang W,Zhang L
Published figure using IFN gamma monoclonal antibody (Product # 45-7311-82) in Flow Cytometry
Sat May 01 00:00:00 EDT 2021
Features of T-cell subset composition in a D-galactose-induced senescence mouse model.
Experimental animals
Kawata K,Suzuki T,Ozawa K,Sekiguchi M
Published figure using IFN gamma monoclonal antibody (Product # 45-7311-82) in Flow Cytometry
Fri Aug 06 00:00:00 EDT 2021
Features of T-cell subset composition in a D-galactose-induced senescence mouse model.
Experimental animals
Kawata K,Suzuki T,Ozawa K,Sekiguchi M
Published figure using IFN gamma monoclonal antibody (Product # 45-7311-82) in Flow Cytometry
Fri Aug 06 00:00:00 EDT 2021
T cell-derived tumor necrosis factor induces cytotoxicity by activating RIPK1-dependent target cell death.
JCI insight
Chun N,Ang RL,Chan M,Fairchild RL,Baldwin WM,Horwitz JK,Gelles JD,Chipuk JE,Kelliher MA,Pavlov VI,Li Y,Homann D,Heeger PS,Ting AT
Published figure using IFN gamma monoclonal antibody (Product # 45-7311-82) in Flow Cytometry
Wed Dec 22 00:00:00 EST 2021
Antitumor efficacy of a neoantigen cancer vaccine delivered by electroporation is influenced by microbiota composition.
Oncoimmunology
Lione L,Salvatori E,Petrazzuolo A,Massacci A,Maggio R,Confroti A,Compagnone M,Aurisicchio L,Ciliberto G,Palombo F
Published figure using IFN gamma monoclonal antibody (Product # 45-7311-82) in Flow Cytometry
Tue Mar 23 00:00:00 EDT 2021
PI3Kδ coordinates transcriptional, chromatin, and metabolic changes to promote effector CD8+ T cells at the expense of central memory.
Cell reports
Cannons JL,Villarino AV,Kapnick SM,Preite S,Shih HY,Gomez-Rodriguez J,Kaul Z,Shibata H,Reilley JM,Huang B,Handon R,McBain IT,Gossa S,Wu T,Su HC,McGavern DB,O'Shea JJ,McGuire PJ,Uzel G,Schwartzberg PL
Published figure using IFN gamma monoclonal antibody (Product # 45-7311-82) in Flow Cytometry
Tue Oct 12 00:00:00 EDT 2021
Expansion of an Unusual Virtual Memory CD8+ Subpopulation Bearing Vα3.2 TCR in Themis-Deficient Mice.
Frontiers in immunology
Prasad M,Wojciech L,Brzostek J,Hu J,Chua YL,Tung DWH,Yap J,Rybakin V,Gascoigne NRJ
Published figure using IFN gamma monoclonal antibody (Product # 45-7311-82) in Flow Cytometry
Thu Sep 23 00:00:00 EDT 2021
Type 1 Cytotoxic T Cells Increase in Placenta after Intrauterine Inflammation.
Frontiers in immunology
Liu J,Liu Y,Panda S,Liu A,Lei J,Burd I
Published figure using IFN gamma monoclonal antibody (Product # 45-7311-82) in Flow Cytometry
Fri Dec 17 00:00:00 EST 2021
Exosome-mediated mRNA delivery in vivo is safe and can be used to induce SARS-CoV-2 immunity.
The Journal of biological chemistry
Tsai SJ,Atai NA,Cacciottolo M,Nice J,Salehi A,Guo C,Sedgwick A,Kanagavelu S,Gould SJ
Published figure using IFN gamma monoclonal antibody (Product # 45-7311-82) in Flow Cytometry
Mon Nov 01 00:00:00 EDT 2021
Engineered macrophages as near-infrared light activated drug vectors for chemo-photodynamic therapy of primary and bone metastatic breast cancer.
Nature communications
Huang Y,Guan Z,Dai X,Shen Y,Wei Q,Ren L,Jiang J,Xiao Z,Jiang Y,Liu D,Huang Z,Xu X,Luo Y,Zhao C
Published figure using IFN gamma monoclonal antibody (Product # 45-7311-82) in Flow Cytometry
Wed Jul 14 00:00:00 EDT 2021
Mechanisms that allow vaccination against an oncolytic vesicular stomatitis virus-encoded transgene to enhance safety without abrogating oncolysis.
Scientific reports
AuYeung AWK,Mould RC,Stegelmeier AA,van Vloten JP,Karimi K,Woods JP,Petrik JJ,Wood GA,Bridle BW
Published figure using IFN gamma monoclonal antibody (Product # 45-7311-82) in Flow Cytometry
Tue Jul 27 00:00:00 EDT 2021
YY1 regulation by miR-124-3p promotes Th17 cell pathogenicity through interaction with T-bet in rheumatoid arthritis.
JCI insight
Lin J,Tang J,Lin J,He Y,Yu Z,Jiang R,Yang B,Ou Q
Published figure using IFN gamma monoclonal antibody (Product # 45-7311-82) in Flow Cytometry
Mon Nov 22 00:00:00 EST 2021
Small Molecule Inhibitors Targeting Nuclear Factor κB Activation Markedly Reduce Expression of Interleukin-2, but Not Interferon-γ, Induced by Phorbol Esters and Calcium Ionophores.
International journal of molecular sciences
Tanaka Y,Nakao A,Miyake Y,Higashi Y,Tanigaki R,Kataoka T
Published figure using IFN gamma monoclonal antibody (Product # 45-7311-82) in Flow Cytometry
Fri Dec 03 00:00:00 EST 2021
SPARC regulation of PMN clearance protects from pristane-induced lupus and rheumatoid arthritis.
iScience
Sangaletti S,Botti L,Gulino A,Lecis D,Bassani B,Portararo P,Milani M,Cancila V,De Cecco L,Dugo M,Tripodo C,Colombo MP
Published figure using IFN gamma monoclonal antibody (Product # 45-7311-82) in Flow Cytometry
Fri Jun 25 00:00:00 EDT 2021
SPARC regulation of PMN clearance protects from pristane-induced lupus and rheumatoid arthritis.
iScience
Sangaletti S,Botti L,Gulino A,Lecis D,Bassani B,Portararo P,Milani M,Cancila V,De Cecco L,Dugo M,Tripodo C,Colombo MP
Published figure using IFN gamma monoclonal antibody (Product # 45-7311-82) in Flow Cytometry
Fri Jun 25 00:00:00 EDT 2021
Non-redundant activity of GSK-3α and GSK-3β in T cell-mediated tumor rejection.
iScience
Steele L,Mannion AJ,Shaw G,Maclennan KA,Cook GP,Rudd CE,Taylor A
Published figure using IFN gamma monoclonal antibody (Product # 45-7311-82) in Flow Cytometry
Fri Jun 25 00:00:00 EDT 2021
Non-redundant activity of GSK-3α and GSK-3β in T cell-mediated tumor rejection.
iScience
Steele L,Mannion AJ,Shaw G,Maclennan KA,Cook GP,Rudd CE,Taylor A
Published figure using IFN gamma monoclonal antibody (Product # 45-7311-82) in Flow Cytometry
Fri Jun 25 00:00:00 EDT 2021
Analysis of T cells in mouse lymphoid tissue and blood with flow cytometry.
STAR protocols
Skordos I,Demeyer A,Beyaert R
Published figure using IFN gamma monoclonal antibody (Product # 45-7311-82) in Flow Cytometry
Fri Mar 19 00:00:00 EDT 2021
A distal enhancer at risk locus 11q13.5 promotes suppression of colitis by Treg cells.
Nature
Nasrallah R,Imianowski CJ,Bossini-Castillo L,Grant FM,Dogan M,Placek L,Kozhaya L,Kuo P,Sadiyah F,Whiteside SK,Mumbach MR,Glinos D,Vardaka P,Whyte CE,Lozano T,Fujita T,Fujii H,Liston A,Andrews S,Cozzani A,Yang J,Mitra S,Lugli E,Chang HY,Unutmaz D,Trynka G,Roychoudhuri R
45-7311 was used in Flow cytometry/Cell sorting to provide a mechanistic basis for association of the 11q13.5 risk locus with immune-mediated diseases and identify GARP as a potential target in their therapy.
Wed Jul 01 00:00:00 EDT 2020
Niche-Selective Inhibition of Pathogenic Th17 Cells by Targeting Metabolic Redundancy.
Cell
Wu L,Hollinshead KER,Hao Y,Au C,Kroehling L,Ng C,Lin WY,Li D,Silva HM,Shin J,Lafaille JJ,Possemato R,Pacold ME,Papagiannakopoulos T,Kimmelman AC,Satija R,Littman DR
45-7311-82 was used in Flow Cytometry to suggest that inhibiting glycolysis by targeting Gpi1 could be an effective therapeutic strategy with minimum toxicity for Th17-mediated autoimmune diseases, and, more generally, that metabolic redundancies can be exploited for selective targeting of disease processes.
Thu Aug 06 00:00:00 EDT 2020
Antagonistic Inflammatory Phenotypes Dictate Tumor Fate and Response to Immune Checkpoint Blockade.
Immunity
Bonavita E,Bromley CP,Jonsson G,Pelly VS,Sahoo S,Walwyn-Brown K,Mensurado S,Moeini A,Flanagan E,Bell CR,Chiang SC,Chikkanna-Gowda CP,Rogers N,Silva-Santos B,Jaillon S,Mantovani A,Reis e Sousa C,Guerra N,Davis DM,Zelenay S
Published figure using IFN gamma monoclonal antibody (Product # 45-7311-82) in Flow Cytometry
Tue Dec 15 00:00:00 EST 2020
Bcl6 and Blimp1 reciprocally regulate ST2+ Treg-cell development in the context of allergic airway inflammation.
The Journal of allergy and clinical immunology
Koh B,Ulrich BJ,Nelson AS,Panangipalli G,Kharwadkar R,Wu W,Xie MM,Fu Y,Turner MJ,Paczesny S,Janga SC,Dent AL,Kaplan MH
45-7311 was used in Flow cytometry/Cell sorting to define the functions of Bcl6 in Treg cells, including Tfr cells, in the context of allergic airway inflammation.
Sun Nov 01 00:00:00 EDT 2020
PD-1 and BTLA regulate T cell signaling differentially and only partially through SHP1 and SHP2.
The Journal of cell biology
Xu X,Hou B,Fulzele A,Masubuchi T,Zhao Y,Wu Z,Hu Y,Jiang Y,Ma Y,Wang H,Bennett EJ,Fu G,Hui E
Published figure using IFN gamma monoclonal antibody (Product # 45-7311-82) in Flow Cytometry
Mon Jun 01 00:00:00 EDT 2020
Runx proteins mediate protective immunity against Leishmania donovani infection by promoting CD40 expression on dendritic cells.
PLoS pathogens
Akhtar MN,Mishra M,Yadav V,Yadav M,Gujar R,Lal S,Kumar R,Khatri N,Sen P
Published figure using IFN gamma monoclonal antibody (Product # 45-7311-82) in Flow Cytometry
Tue Dec 01 00:00:00 EST 2020
Astrocytes promote a protective immune response to brain Toxoplasma gondii infection via IL-33-ST2 signaling.
PLoS pathogens
Still KM,Batista SJ,O'Brien CA,Oyesola OO,Früh SP,Webb LM,Smirnov I,Kovacs MA,Cowan MN,Hayes NW,Thompson JA,Tait Wojno ED,Harris TH
45-7311 was used in Flow cytometry/Cell sorting to show that IL-33 is expressed by oligodendrocytes and astrocytes during T. gondii infection, is released locally into the cerebrospinal fluid of T. gondii-infected animals, and is required for control of infection.
Thu Oct 01 00:00:00 EDT 2020
Expression of CD27 and CD28 on γδ T cells from the peripheral blood of patients with allergic rhinitis.
Experimental and therapeutic medicine
Wang Q,Sun Q,Chen Q,Li H,Liu D
Published figure using IFN gamma monoclonal antibody (Product # 45-7311-82) in Flow Cytometry
Tue Dec 01 00:00:00 EST 2020
Increase in liver γδ T cells with concurrent augmentation of IFN-β production during the early stages of a mouse model of acute experimental hepatitis B virus infection.
Experimental and therapeutic medicine
Chang L,Wang L,Ling N,Peng H,Chen M
Published figure using IFN gamma monoclonal antibody (Product # 45-7311-82) in Flow Cytometry
Wed Jan 01 00:00:00 EST 2020
Isolation and functional characterisation of lamina propria leukocytes from helminth-infected, murine small intestine.
Journal of immunological methods
Webster HC,Andrusaite AT,Shergold AL,Milling SWF,Perona-Wright G
Published figure using IFN gamma monoclonal antibody (Product # 45-7311-82) in Flow Cytometry
Sat Feb 01 00:00:00 EST 2020
Lysosomal Acid Lipase Is Required for Donor T Cells to Induce Graft-versus-Host Disease.
Cell reports
Nguyen HD,Ticer T,Bastian D,Kuril S,Li H,Du H,Yan C,Yu XZ
Published figure using IFN gamma monoclonal antibody (Product # 45-7311-82) in Flow Cytometry
Tue Oct 27 00:00:00 EDT 2020
Lysosomal Acid Lipase Is Required for Donor T Cells to Induce Graft-versus-Host Disease.
Cell reports
Nguyen HD,Ticer T,Bastian D,Kuril S,Li H,Du H,Yan C,Yu XZ
Published figure using IFN gamma monoclonal antibody (Product # 45-7311-82) in Flow Cytometry
Tue Oct 27 00:00:00 EDT 2020
C5aR1 Activation Drives Early IFN-γ Production to Control Experimental Toxoplasma gondii Infection.
Frontiers in immunology
Briukhovetska D,Ohm B,Mey FT,Aliberti J,Kleingarn M,Huber-Lang M,Karsten CM,Köhl J
Published figure using IFN gamma monoclonal antibody (Product # 45-7311-82) in Flow Cytometry
Mon Apr 05 00:00:00 EDT 2021
Immunotherapeutic Blockade of CD47 Inhibitory Signaling Enhances Innate and Adaptive Immune Responses to Viral Infection.
Cell reports
Cham LB,Torrez Dulgeroff LB,Tal MC,Adomati T,Li F,Bhat H,Huang A,Lang PA,Moreno ME,Rivera JM,Galkina SA,Kosikova G,Stoddart CA,McCune JM,Myers LM,Weissman IL,Lang KS,Hasenkrug KJ
Published figure using IFN gamma monoclonal antibody (Product # 45-7311-82) in Flow Cytometry
Tue Apr 14 00:00:00 EDT 2020
FUT1 deficiency elicits immune dysregulation and corneal opacity in steady state and under stress.
Cell death & disease
Kim KW,Ryu JS,Ko JH,Kim JY,Kim HJ,Lee HJ,Oh JH,Chung JH,Oh JY
Published figure using IFN gamma monoclonal antibody (Product # 45-7311-82) in Flow Cytometry
Fri Apr 24 00:00:00 EDT 2020
Deletion of immune evasion genes provides an effective vaccine design for tumor-associated herpesviruses.
NPJ vaccines
Brar G,Farhat NA,Sukhina A,Lam AK,Kim YH,Hsu T,Tong L,Lin WW,Ware CF,Blackman MA,Sun R,Wu TT
Published figure using IFN gamma monoclonal antibody (Product # 45-7311-82) in Flow Cytometry
Thu Nov 05 00:00:00 EST 2020
Comparative Analysis of Age-Related Changes in Lacrimal Glands and Meibomian Glands of a C57BL/6 Male Mouse Model.
International journal of molecular sciences
Yoon CH,Ryu JS,Hwang HS,Kim MK
Published figure using IFN gamma monoclonal antibody (Product # 45-7311-82) in Flow Cytometry
Thu Jun 11 00:00:00 EDT 2020
BCG vaccination reduces the mortality of Mycobacterium tuberculosis-infected type 2 diabetes mellitus mice.
JCI insight
Radhakrishnan RK,Thandi RS,Tripathi D,Paidipally P,McAllister MK,Mulik S,Samten B,Vankayalapati R
Published figure using IFN gamma monoclonal antibody (Product # 45-7311-82) in Flow Cytometry
Thu Mar 12 00:00:00 EDT 2020
Tumors induce de novo steroid biosynthesis in T cells to evade immunity.
Nature communications
Mahata B,Pramanik J,van der Weyden L,Polanski K,Kar G,Riedel A,Chen X,Fonseca NA,Kundu K,Campos LS,Ryder E,Duddy G,Walczak I,Okkenhaug K,Adams DJ,Shields JD,Teichmann SA
Published figure using IFN gamma monoclonal antibody (Product # 45-7311-82) in Flow Cytometry
Fri Jul 17 00:00:00 EDT 2020
Tumors induce de novo steroid biosynthesis in T cells to evade immunity.
Nature communications
Mahata B,Pramanik J,van der Weyden L,Polanski K,Kar G,Riedel A,Chen X,Fonseca NA,Kundu K,Campos LS,Ryder E,Duddy G,Walczak I,Okkenhaug K,Adams DJ,Shields JD,Teichmann SA
Published figure using IFN gamma monoclonal antibody (Product # 45-7311-82) in Flow Cytometry
Fri Jul 17 00:00:00 EDT 2020
Targeting the orphan nuclear receptor NR2F6 in T cells primes tumors for immune checkpoint therapy.
Cell communication and signaling : CCS
Klepsch V,Pommermayr M,Humer D,Brigo N,Hermann-Kleiter N,Baier G
Published figure using IFN gamma monoclonal antibody (Product # 45-7311-82) in Flow Cytometry
Tue Jan 14 00:00:00 EST 2020
TAGAP instructs Th17 differentiation by bridging Dectin activation to EPHB2 signaling in innate antifungal response.
Nature communications
Chen J,He R,Sun W,Gao R,Peng Q,Zhu L,Du Y,Ma X,Guo X,Zhang H,Tan C,Wang J,Zhang W,Weng X,Man J,Bauer H,Wang QK,Martin BN,Zhang CJ,Li X,Wang C
Published figure using IFN gamma monoclonal antibody (Product # 45-7311-82) in Flow Cytometry
Mon Apr 20 00:00:00 EDT 2020
Senolytics prevent mt-DNA-induced inflammation and promote the survival of aged organs following transplantation.
Nature communications
Iske J,Seyda M,Heinbokel T,Maenosono R,Minami K,Nian Y,Quante M,Falk CS,Azuma H,Martin F,Passos JF,Niemann CU,Tchkonia T,Kirkland JL,Elkhal A,Tullius SG
Published figure using IFN gamma monoclonal antibody (Product # 45-7311-82) in Flow Cytometry
Thu Aug 27 00:00:00 EDT 2020
PCC0208025 (BMS202), a small molecule inhibitor of PD-L1, produces an antitumor effect in B16-F10 melanoma-bearing mice.
PloS one
Hu Z,Yu P,Du G,Wang W,Zhu H,Li N,Zhao H,Dong Z,Ye L,Tian J
Published figure using IFN gamma monoclonal antibody (Product # 45-7311-82) in Flow Cytometry
Mon Jun 22 00:00:00 EDT 2020
Rhein modulates host purine metabolism in intestine through gut microbiota and ameliorates experimental colitis.
Theranostics
Wu J,Wei Z,Cheng P,Qian C,Xu F,Yang Y,Wang A,Chen W,Sun Z,Lu Y
45-7311 was used in Flow cytometry/Cell sorting to investigate the effect of rhein on colitis and studied its possible mechanisms.
Mon May 31 00:00:00 EDT 2021
Salt Sensing by Serum/Glucocorticoid-Regulated Kinase 1 Promotes Th17-like Inflammatory Adaptation of Foxp3+ Regulatory T Cells.
Cell reports
Yang YH,Istomine R,Alvarez F,Al-Aubodah TA,Shi XQ,Takano T,Thornton AM,Shevach EM,Zhang J,Piccirillo CA
45-7311-82 was used in Flow Cytometry to show that high salt (HS) drives thymic Treg cells to adopt a T helper type 17 (Th17)-like phenotype and enhances generation of Th17-like induced Treg cells in a SGK1-dependent manner, all the while maintaining suppressive function.
Tue Feb 04 00:00:00 EST 2020
Osteoprotegerin-dependent M cell self-regulation balances gut infection and immunity.
Nature communications
Kimura S,Nakamura Y,Kobayashi N,Shiroguchi K,Kawakami E,Mutoh M,Takahashi-Iwanaga H,Yamada T,Hisamoto M,Nakamura M,Udagawa N,Sato S,Kaisho T,Iwanaga T,Hase K
45-7311 was used in Flow cytometry/Cell sorting to identify that the balance between infectious risk and the ability to perform immunosurveillance at the mucosal surface is dependent on osteprotegerin-dependent self-regulation of M cell differentiation.
Mon Jan 13 00:00:00 EST 2020
Bmal1 integrates mitochondrial metabolism and macrophage activation.
eLife
Alexander RK,Liou YH,Knudsen NH,Starost KA,Xu C,Hyde AL,Liu S,Jacobi D,Liao NS,Lee CH
Published figure using IFN gamma monoclonal antibody (Product # 45-7311-82) in Flow Cytometry
Tue May 12 00:00:00 EDT 2020
Tolerogenic Immunomodulation by PEGylated Antigenic Peptides.
Frontiers in immunology
Pfeil J,Simonetti M,Lauer U,Volkmer R,von Thülen B,Durek P,Krähmer R,Leenders F,Hamann A,Hoffmann U
Published figure using IFN gamma monoclonal antibody (Product # 45-7311-82) in Flow Cytometry
Thu Apr 29 00:00:00 EDT 2021
Bixin Attenuates Experimental Autoimmune Encephalomyelitis by Suppressing TXNIP/NLRP3 Inflammasome Activity and Activating NRF2 Signaling.
Frontiers in immunology
Yu Y,Wu DM,Li J,Deng SH,Liu T,Zhang T,He M,Zhao YY,Xu Y
Published figure using IFN gamma monoclonal antibody (Product # 45-7311-82) in Flow Cytometry
Mon Jun 21 00:00:00 EDT 2021
Specific targeting of CD163+ TAMs mobilizes inflammatory monocytes and promotes T cell-mediated tumor regression.
The Journal of experimental medicine
Etzerodt A,Tsalkitzi K,Maniecki M,Damsky W,Delfini M,Baudoin E,Moulin M,Bosenberg M,Graversen JH,Auphan-Anezin N,Moestrup SK,Lawrence T
Published figure using IFN gamma monoclonal antibody (Product # 45-7311-82) in Flow Cytometry
Mon Oct 07 00:00:00 EDT 2019
Specific targeting of CD163+ TAMs mobilizes inflammatory monocytes and promotes T cell-mediated tumor regression.
The Journal of experimental medicine
Etzerodt A,Tsalkitzi K,Maniecki M,Damsky W,Delfini M,Baudoin E,Moulin M,Bosenberg M,Graversen JH,Auphan-Anezin N,Moestrup SK,Lawrence T
Published figure using IFN gamma monoclonal antibody (Product # 45-7311-82) in Flow Cytometry
Mon Oct 07 00:00:00 EDT 2019
BTK signaling drives CD1dhiCD5+ regulatory B-cell differentiation to promote pancreatic carcinogenesis.
Oncogene
Das S,Bar-Sagi D
Published figure using IFN gamma monoclonal antibody (Product # 45-7311-82) in Flow Cytometry
Mon Apr 01 00:00:00 EDT 2019
The ROP16III-dependent early immune response determines the subacute CNS immune response and type III Toxoplasma gondii survival.
PLoS pathogens
Tuladhar S,Kochanowsky JA,Bhaskara A,Ghotmi Y,Chandrasekaran S,Koshy AA
Published figure using IFN gamma monoclonal antibody (Product # 45-7311-82) in Flow Cytometry
Tue Oct 01 00:00:00 EDT 2019
CD8+ T cells promote cytokine responses to stress.
Cytokine
Clark SM,Song C,Li X,Keegan AD,Tonelli LH
Published figure using IFN gamma monoclonal antibody (Product # 45-7311-82) in Flow Cytometry
Tue Jan 01 00:00:00 EST 2019
IL-31 plays dual roles in lung inflammation in an OVA-induced murine asthma model.
Biology open
Huang J,Yue H,Jiang T,Gao J,Shi Y,Shi B,Wu X,Gou X
Published figure using IFN gamma monoclonal antibody (Product # 45-7311-82) in Flow Cytometry
Tue Jan 15 00:00:00 EST 2019
An attenuated Zika virus NS4B protein mutant is a potent inducer of antiviral immune responses.
NPJ vaccines
Li G,Adam A,Luo H,Shan C,Cao Z,Fontes-Garfias CR,Sarathy VV,Teleki C,Winkelmann ER,Liang Y,Sun J,Bourne N,Barrett ADT,Shi PY,Wang T
Published figure using IFN gamma monoclonal antibody (Product # 45-7311-82) in Flow Cytometry
Thu Oct 01 00:00:00 EDT 2020
Tpl2 Protects Against Fulminant Hepatitis Through Mobilization of Myeloid-Derived Suppressor Cells.
Frontiers in immunology
Xu J,Pei S,Wang Y,Liu J,Qian Y,Huang M,Zhang Y,Xiao Y
Published figure using IFN gamma monoclonal antibody (Product # 45-7311-82) in Flow Cytometry
Wed Oct 14 00:00:00 EDT 2020
A chemical biology toolbox to study protein methyltransferases and epigenetic signaling.
Nature communications
Scheer S,Ackloo S,Medina TS,Schapira M,Li F,Ward JA,Lewis AM,Northrop JP,Richardson PL,Kaniskan HÜ,Shen Y,Liu J,Smil D,McLeod D,Zepeda-Velazquez CA,Luo M,Jin J,Barsyte-Lovejoy D,Huber KVM,De Carvalho DD,Vedadi M,Zaph C,Brown PJ,Arrowsmith CH
Published figure using IFN gamma monoclonal antibody (Product # 45-7311-82) in Flow Cytometry
Thu Jan 03 00:00:00 EST 2019
ER stress-induced mediator C/EBP homologous protein thwarts effector T cell activity in tumors through T-bet repression.
Nature communications
Cao Y,Trillo-Tinoco J,Sierra RA,Anadon C,Dai W,Mohamed E,Cen L,Costich TL,Magliocco A,Marchion D,Klar R,Michel S,Jaschinski F,Reich RR,Mehrotra S,Cubillos-Ruiz JR,Munn DH,Conejo-Garcia JR,Rodriguez PC
Published figure using IFN gamma monoclonal antibody (Product # 45-7311-82) in Flow Cytometry
Wed Mar 20 00:00:00 EDT 2019
Inflammation induced by incomplete radiofrequency ablation accelerates tumor progression and hinders PD-1 immunotherapy.
Nature communications
Shi L,Wang J,Ding N,Zhang Y,Zhu Y,Dong S,Wang X,Peng C,Zhou C,Zhou L,Li X,Shi H,Wu W,Long X,Wu C,Liao W
Published figure using IFN gamma monoclonal antibody (Product # 45-7311-82) in Flow Cytometry
Thu Nov 28 00:00:00 EST 2019
Requirement of Mitochondrial Transcription Factor A in Tissue-Resident Regulatory T Cell Maintenance and Function.
Cell reports
Fu Z,Ye J,Dean JW,Bostick JW,Weinberg SE,Xiong L,Oliff KN,Chen ZE,Avram D,Chandel NS,Zhou L
Published figure using IFN gamma monoclonal antibody (Product # 45-7311-82) in Flow Cytometry
Tue Jul 02 00:00:00 EDT 2019
The droplet size of emulsion adjuvants has significant impact on their potency, due to differences in immune cell-recruitment and -activation.
Scientific reports
Shah RR,Taccone M,Monaci E,Brito LA,Bonci A,O'Hagan DT,Amiji MM,Seubert A
45-7311-82 was used in Flow Cytometry to deduce the considerable impact of emulsion droplet size and composition on the ability to recruit and activate immune cells.
Thu Aug 08 00:00:00 EDT 2019
Innate-Like Lymphocytes Are Immediate Participants in the Hyper-Acute Immune Response to Trauma and Hemorrhagic Shock.
Frontiers in immunology
Manson J,Hoffman R,Chen S,Ramadan MH,Billiar TR
Published figure using IFN gamma monoclonal antibody (Product # 45-7311-82) in Flow Cytometry
Tue Oct 13 00:00:00 EDT 2020
Mitophagy in Intestinal Epithelial Cells Triggers Adaptive Immunity during Tumorigenesis.
Cell
Ziegler PK,Bollrath J,Pallangyo CK,Matsutani T,Canli Ö,De Oliveira T,Diamanti MA,Müller N,Gamrekelashvili J,Putoczki T,Horst D,Mankan AK,Öner MG,Müller S,Müller-Höcker J,Kirchner T,Slotta-Huspenina J,Taketo MM,Reinheckel T,Dröse S,Larner AC,Wels WS,Ernst M,Greten TF,Arkan MC,Korn T,Wirth D,Greten FR
Published figure using IFN gamma monoclonal antibody (Product # 45-7311-82) in Flow Cytometry
Thu Jun 28 00:00:00 EDT 2018
Mitophagy in Intestinal Epithelial Cells Triggers Adaptive Immunity during Tumorigenesis.
Cell
Ziegler PK,Bollrath J,Pallangyo CK,Matsutani T,Canli Ö,De Oliveira T,Diamanti MA,Müller N,Gamrekelashvili J,Putoczki T,Horst D,Mankan AK,Öner MG,Müller S,Müller-Höcker J,Kirchner T,Slotta-Huspenina J,Taketo MM,Reinheckel T,Dröse S,Larner AC,Wels WS,Ernst M,Greten TF,Arkan MC,Korn T,Wirth D,Greten FR
Published figure using IFN gamma monoclonal antibody (Product # 45-7311-82) in Flow Cytometry
Thu Jun 28 00:00:00 EDT 2018
Initiation of Antiviral B Cell Immunity Relies on Innate Signals from Spatially Positioned NKT Cells.
Cell
Gaya M,Barral P,Burbage M,Aggarwal S,Montaner B,Warren Navia A,Aid M,Tsui C,Maldonado P,Nair U,Ghneim K,Fallon PG,Sekaly RP,Barouch DH,Shalek AK,Bruckbauer A,Strid J,Batista FD
Published figure using IFN gamma monoclonal antibody (Product # 45-7311-82) in Flow Cytometry
Thu Jan 25 00:00:00 EST 2018
SYK-CARD9 Signaling Axis Promotes Gut Fungi-Mediated Inflammasome Activation to Restrict Colitis and Colon Cancer.
Immunity
Malik A,Sharma D,Malireddi RKS,Guy CS,Chang TC,Olsen SR,Neale G,Vogel P,Kanneganti TD
Published figure using IFN gamma monoclonal antibody (Product # 45-7311-82) in Flow Cytometry
Tue Sep 18 00:00:00 EDT 2018
Critical Role for the Microbiota in CX3CR1+ Intestinal Mononuclear Phagocyte Regulation of Intestinal T Cell Responses.
Immunity
Kim M,Galan C,Hill AA,Wu WJ,Fehlner-Peach H,Song HW,Schady D,Bettini ML,Simpson KW,Longman RS,Littman DR,Diehl GE
45-7311 was used in Flow cytometry/Cell sorting to identify a cellular mechanism by which the microbiota limits intestinal inflammation and promotes tissue homeostasis.
Tue Jul 17 00:00:00 EDT 2018
A Macrophage Colony-Stimulating-Factor-Producing γδ T Cell Subset Prevents Malarial Parasitemic Recurrence.
Immunity
Mamedov MR,Scholzen A,Nair RV,Cumnock K,Kenkel JA,Oliveira JHM,Trujillo DL,Saligrama N,Zhang Y,Rubelt F,Schneider DS,Chien YH,Sauerwein RW,Davis MM
45-7311-82 was used in Flow Cytometry to point to an M-CSF-producing γδ T cell subset that fulfills a specialized protective role in the later stage of malaria infection when αβ T cells have declined.
Tue Feb 20 00:00:00 EST 2018
Autoimmune Th17 Cells Induced Synovial Stromal and Innate Lymphoid Cell Secretion of the Cytokine GM-CSF to Initiate and Augment Autoimmune Arthritis.
Immunity
Hirota K,Hashimoto M,Ito Y,Matsuura M,Ito H,Tanaka M,Watanabe H,Kondoh G,Tanaka A,Yasuda K,Kopf M,Potocnik AJ,Stockinger B,Sakaguchi N,Sakaguchi S
Published figure using IFN gamma monoclonal antibody (Product # 45-7311-82) in Flow Cytometry
Tue Jun 19 00:00:00 EDT 2018
Cambogin suppresses dextran sulphate sodium-induced colitis by enhancing Treg cell stability and function.
British journal of pharmacology
Lu Y,Kim NM,Jiang YW,Zhang H,Zheng D,Zhu FX,Liang R,Li B,Xu HX
Published figure using IFN gamma monoclonal antibody (Product # 45-7311-82) in Flow Cytometry
Sun Apr 01 00:00:00 EDT 2018
The intestinal microbiota determines the colitis-inducing potential of T-bet-deficient Th cells in mice.
European journal of immunology
Zimmermann J,Durek P,Kühl AA,Schattenberg F,Maschmeyer P,Siracusa F,Lehmann K,Westendorf K,Weber M,Riedel R,Müller S,Radbruch A,Chang HD
45-7311 was used in Flow cytometry/Cell sorting to study the dominance of the microbiota over particular T cell differentiation programs in the pathogenesis of chronic intestinal inflammation.
Mon Jan 01 00:00:00 EST 2018
MicroRNA-126 deficiency enhanced the activation and function of CD4+ T cells by elevating IRS-1 pathway.
Clinical and experimental immunology
Chu F,Hu Y,Zhou Y,Guo M,Lu J,Zheng W,Xu H,Zhao J,Xu L
Published figure using IFN gamma monoclonal antibody (Product # 45-7311-82) in Flow Cytometry
Thu Feb 01 00:00:00 EST 2018
Baicalin Downregulates RLRs Signaling Pathway to Control Influenza A Virus Infection and Improve the Prognosis.
Evidence-based complementary and alternative medicine : eCAM
Pang P,Zheng K,Wu S,Xu H,Deng L,Shi Y,Chen X
Published figure using IFN gamma monoclonal antibody (Product # 45-7311-82) in Flow Cytometry
Thu Oct 01 00:00:00 EDT 2020
mTOR Modulates CD8+ T Cell Differentiation in Mice with Invasive Pulmonary Aspergillosis.
Open life sciences
Wang H,Xiao Y,Su L,Cui N,Liu D
Published figure using IFN gamma monoclonal antibody (Product # 45-7311-82) in Flow Cytometry
Mon Jan 01 00:00:00 EST 2018
Mrp1 is involved in lipid presentation and iNKT cell activation by Streptococcus pneumoniae.
Nature communications
Chandra S,Gray J,Kiosses WB,Khurana A,Hitomi K,Crosby CM,Chawla A,Fu Z,Zhao M,Veerapen N,Richardson SK,Porcelli SA,Besra G,Howell AR,Sharma S,Peters B,Kronenberg M
Published figure using IFN gamma monoclonal antibody (Product # 45-7311-82) in Flow Cytometry
Mon Oct 15 00:00:00 EDT 2018
Modifying the cancer-immune set point using vaccinia virus expressing re-designed interleukin-2.
Nature communications
Liu Z,Ge Y,Wang H,Ma C,Feist M,Ju S,Guo ZS,Bartlett DL
Published figure using IFN gamma monoclonal antibody (Product # 45-7311-82) in Flow Cytometry
Thu Nov 08 00:00:00 EST 2018
Oncofetal gene SALL4 reactivation by hepatitis B virus counteracts miR-200c in PD-L1-induced T cell exhaustion.
Nature communications
Sun C,Lan P,Han Q,Huang M,Zhang Z,Xu G,Song J,Wang J,Wei H,Zhang J,Sun R,Zhang C,Tian Z
Published figure using IFN gamma monoclonal antibody (Product # 45-7311-82) in Flow Cytometry
Wed Mar 28 00:00:00 EDT 2018
Peroxisomal β-oxidation regulates whole body metabolism, inflammatory vigor, and pathogenesis of nonalcoholic fatty liver disease.
JCI insight
Moreno-Fernandez ME,Giles DA,Stankiewicz TE,Sheridan R,Karns R,Cappelletti M,Lampe K,Mukherjee R,Sina C,Sallese A,Bridges JP,Hogan SP,Aronow BJ,Hoebe K,Divanovic S
Published figure using IFN gamma monoclonal antibody (Product # 45-7311-82) in Flow Cytometry
Thu Mar 22 00:00:00 EDT 2018
Regulation of chitinase-3-like-1 in T cell elicits Th1 and cytotoxic responses to inhibit lung metastasis.
Nature communications
Kim DH,Park HJ,Lim S,Koo JH,Lee HG,Choi JO,Oh JH,Ha SJ,Kang MJ,Lee CM,Lee CG,Elias JA,Choi JM
Published figure using IFN gamma monoclonal antibody (Product # 45-7311-82) in Flow Cytometry
Mon Feb 05 00:00:00 EST 2018
Genome-wide analyses reveal the IRE1a-XBP1 pathway promotes T helper cell differentiation by resolving secretory stress and accelerating proliferation.
Genome medicine
Pramanik J,Chen X,Kar G,Henriksson J,Gomes T,Park JE,Natarajan K,Meyer KB,Miao Z,McKenzie ANJ,Mahata B,Teichmann SA
45-7311 was used in Flow cytometry/Cell sorting to identify direct target genes of XBP1 and define XBP1's regulatory network.
Wed Oct 24 00:00:00 EDT 2018
A CCR4 antagonist reverses the tumor-promoting microenvironment of renal cancer.
The Journal of clinical investigation
Berlato C,Khan MN,Schioppa T,Thompson R,Maniati E,Montfort A,Jangani M,Canosa M,Kulbe H,Hagemann UB,Duncan AR,Fletcher L,Wilkinson RW,Powles T,Quezada SA,Balkwill FR
Published figure using IFN gamma monoclonal antibody (Product # 45-7311-82) in Flow Cytometry
Wed Mar 01 00:00:00 EST 2017
Excessive expression of miR-27 impairs Treg-mediated immunological tolerance.
The Journal of clinical investigation
Cruz LO,Hashemifar SS,Wu CJ,Cho S,Nguyen DT,Lin LL,Khan AA,Lu LF
Published figure using IFN gamma monoclonal antibody (Product # 45-7311-82) in Flow Cytometry
Wed Feb 01 00:00:00 EST 2017
Combined antiangiogenic and anti-PD-L1 therapy stimulates tumor immunity through HEV formation.
Science translational medicine
Allen E,Jabouille A,Rivera LB,Lodewijckx I,Missiaen R,Steri V,Feyen K,Tawney J,Hanahan D,Michael IP,Bergers G
Published figure using IFN gamma monoclonal antibody (Product # 45-7311-82) in Flow Cytometry
Wed Apr 12 00:00:00 EDT 2017
Egr2 and 3 control adaptive immune responses by temporally uncoupling expansion from T cell differentiation.
The Journal of experimental medicine
Miao T,Symonds ALJ,Singh R,Symonds JD,Ogbe A,Omodho B,Zhu B,Li S,Wang P
Published figure using IFN gamma monoclonal antibody (Product # 45-7311-82) in Flow Cytometry
Mon Jun 05 00:00:00 EDT 2017
Microbial, metabolomic, and immunologic dynamics in a relapsing genetic mouse model of colitis induced by T-synthase deficiency.
Gut microbes
Jacobs JP,Lin L,Goudarzi M,Ruegger P,McGovern DP,Fornace AJ,Borneman J,Xia L,Braun J
Published figure using IFN gamma monoclonal antibody (Product # 45-7311-82) in Flow Cytometry
Mon Jan 02 00:00:00 EST 2017
A New Adjuvant MTOM Mediates Mycobacterium tuberculosis Subunit Vaccine to Enhance Th1-Type T Cell Immune Responses and IL-2+ T Cells.
Frontiers in immunology
Yu Q,Wang X,Fan X
Published figure using IFN gamma monoclonal antibody (Product # 45-7311-82) in Flow Cytometry
Wed Nov 20 00:00:00 EST 2019
Critical role of caspase-8-mediated IL-1 signaling in promoting Th2 responses during asthma pathogenesis.
Mucosal immunology
Qi X,Gurung P,Malireddi RK,Karmaus PW,Sharma D,Vogel P,Chi H,Green DR,Kanneganti TD
Published figure using IFN gamma monoclonal antibody (Product # 45-7311-82) in Flow Cytometry
Sun Jan 01 00:00:00 EST 2017
Betulin from Hedyotis hedyotidea ameliorates concanavalin A-induced and T cell-mediated autoimmune hepatitis in mice.
Acta pharmacologica Sinica
Zhou YQ,Weng XF,Dou R,Tan XS,Zhang TT,Fang JB,Wu XW
Published figure using IFN gamma monoclonal antibody (Product # 45-7311-82) in Flow Cytometry
Wed Feb 01 00:00:00 EST 2017
Role of Triggering Receptor Expressed on Myeloid Cell-1 Expression in Mammalian Target of Rapamycin Modulation of CD8+ T-cell Differentiation during the Immune Response to Invasive Pulmonary Aspergillosis.
Chinese medical journal
Cui N,Wang H,Su LX,Zhang JH,Long Y,Liu DW
Published figure using IFN gamma monoclonal antibody (Product # 45-7311-82) in Flow Cytometry
Sat May 20 00:00:00 EDT 2017
Batf3-dependent CD8α+ Dendritic Cells Aggravates Atherosclerosis via Th1 Cell Induction and Enhanced CCL5 Expression in Plaque Macrophages.
EBioMedicine
Li Y,Liu X,Duan W,Tian H,Zhu G,He H,Yao S,Yi S,Song W,Tang H
Published figure using IFN gamma monoclonal antibody (Product # 45-7311-82) in Flow Cytometry
Sat Apr 01 00:00:00 EDT 2017
Paeoniflorin Ameliorates Experimental Autoimmune Encephalomyelitis via Inhibition of Dendritic Cell Function and Th17 Cell Differentiation.
Scientific reports
Zhang H,Qi Y,Yuan Y,Cai L,Xu H,Zhang L,Su B,Nie H
Published figure using IFN gamma monoclonal antibody (Product # 45-7311-82) in Flow Cytometry
Mon Feb 06 00:00:00 EST 2017
IL-12 Influence mTOR to Modulate CD8+ T Cells Differentiation through T-bet and Eomesodermin in Response to Invasive Pulmonary Aspergillosis.
International journal of medical sciences
Wang H,Li J,Han Q,Yang F,Xiao Y,Xiao M,Xu Y,Su L,Cui N,Liu D
Published figure using IFN gamma monoclonal antibody (Product # 45-7311-82) in Flow Cytometry
Mon May 21 00:00:00 EDT 2018
The TLR7 agonist imiquimod induces anti-cancer effects via autophagic cell death and enhances anti-tumoral and systemic immunity during radiotherapy for melanoma.
Oncotarget
Cho JH,Lee HJ,Ko HJ,Yoon BI,Choe J,Kim KC,Hahn TW,Han JA,Choi SS,Jung YM,Lee KH,Lee YS,Jung YJ
Published figure using IFN gamma monoclonal antibody (Product # 45-7311-82) in Flow Cytometry
Tue Apr 11 00:00:00 EDT 2017
Essential role for CCR6 in certain inflammatory diseases demonstrated using specific antagonist and knockin mice.
JCI insight
Robert R,Ang C,Sun G,Juglair L,Lim EX,Mason LJ,Payne NL,Bernard CC,Mackay CR
Published figure using IFN gamma monoclonal antibody (Product # 45-7311-82) in Flow Cytometry
Thu Aug 03 00:00:00 EDT 2017
A Mouse Model of West Nile Virus Infection.
Current protocols in mouse biology
Graham JB,Swarts JL,Lund JM
45-7311 was used in Flow cytometry/Cell sorting to develop a mouse model to study the breadth of symptoms and disease severity seen in human West Nile virus infection.
Wed Dec 20 00:00:00 EST 2017
Extrafollicular CD4+ T-B interactions are sufficient for inducing autoimmune-like chronic graft-versus-host disease.
Nature communications
Deng R,Hurtz C,Song Q,Yue C,Xiao G,Yu H,Wu X,Muschen M,Forman S,Martin PJ,Zeng D
Published figure using IFN gamma monoclonal antibody (Product # 45-7311-82) in Flow Cytometry
Tue Oct 17 00:00:00 EDT 2017
A Multistage Subunit Vaccine Effectively Protects Mice Against Primary Progressive Tuberculosis, Latency and Reactivation.
EBioMedicine
Ma J,Teng X,Wang X,Fan X,Wu Y,Tian M,Zhou Z,Li L
Published figure using IFN gamma monoclonal antibody (Product # 45-7311-82) in Flow Cytometry
Tue Aug 01 00:00:00 EDT 2017
NLRC3 is an inhibitory sensor of PI3K-mTOR pathways in cancer.
Nature
Karki R,Man SM,Malireddi RKS,Kesavardhana S,Zhu Q,Burton AR,Sharma BR,Qi X,Pelletier S,Vogel P,Rosenstiel P,Kanneganti TD
Published figure using IFN gamma monoclonal antibody (Product # 45-7311-82) in Flow Cytometry
Thu Dec 22 00:00:00 EST 2016
Host-Protozoan Interactions Protect from Mucosal Infections through Activation of the Inflammasome.
Cell
Chudnovskiy A,Mortha A,Kana V,Kennard A,Ramirez JD,Rahman A,Remark R,Mogno I,Ng R,Gnjatic S,Amir ED,Solovyov A,Greenbaum B,Clemente J,Faith J,Belkaid Y,Grigg ME,Merad M
Published figure using IFN gamma monoclonal antibody (Product # 45-7311-82) in Flow Cytometry
Thu Oct 06 00:00:00 EDT 2016
Oxygen Sensing by T Cells Establishes an Immunologically Tolerant Metastatic Niche.
Cell
Clever D,Roychoudhuri R,Constantinides MG,Askenase MH,Sukumar M,Klebanoff CA,Eil RL,Hickman HD,Yu Z,Pan JH,Palmer DC,Phan AT,Goulding J,Gattinoni L,Goldrath AW,Belkaid Y,Restifo NP
Published figure using IFN gamma monoclonal antibody (Product # 45-7311-82) in Flow Cytometry
Thu Aug 25 00:00:00 EDT 2016
Maternal-Derived Hepatitis B Virus e Antigen Alters Macrophage Function in Offspring to Drive Viral Persistence after Vertical Transmission.
Immunity
Tian Y,Kuo CF,Akbari O,Ou JH
Published figure using IFN gamma monoclonal antibody (Product # 45-7311-82) in Flow Cytometry
Tue May 17 00:00:00 EDT 2016
Foxp3 and Toll-like receptor signaling balance Treg cell anabolic metabolism for suppression.
Nature immunology
Gerriets VA,Kishton RJ,Johnson MO,Cohen S,Siska PJ,Nichols AG,Warmoes MO,de Cubas AA,MacIver NJ,Locasale JW,Turka LA,Wells AD,Rathmell JC
Published figure using IFN gamma monoclonal antibody (Product # 45-7311-82) in Flow Cytometry
Thu Dec 01 00:00:00 EST 2016
Oligodendrocyte death results in immune-mediated CNS demyelination.
Nature neuroscience
Traka M,Podojil JR,McCarthy DP,Miller SD,Popko B
Published figure using IFN gamma monoclonal antibody (Product # 45-7311-82) in Flow Cytometry
Fri Jan 01 00:00:00 EST 2016
Metabolic reprogramming of alloantigen-activated T cells after hematopoietic cell transplantation.
The Journal of clinical investigation
Nguyen HD,Chatterjee S,Haarberg KM,Wu Y,Bastian D,Heinrichs J,Fu J,Daenthanasanmak A,Schutt S,Shrestha S,Liu C,Wang H,Chi H,Mehrotra S,Yu XZ
45-7311 was used in Flow cytometry/Cell sorting to study the metabolic reprogramming of donor T cells following allogeneic haematopoietic cell transplantation.
Fri Apr 01 00:00:00 EDT 2016
Interleukin-21 signaling in B cells, but not in T cells, is indispensable for the development of collagen-induced arthritis in mice.
Arthritis research & therapy
Sakuraba K,Oyamada A,Fujimura K,Spolski R,Iwamoto Y,Leonard WJ,Yoshikai Y,Yamada H
45-7311 was used in Flow cytometry/Cell sorting to study the role of IL-21 signalling in B and T cells in collagen-induced arthritis.
Wed Aug 17 00:00:00 EDT 2016
Age-dependent divergent effects of OX40L treatment on the development of diabetes in NOD mice.
Autoimmunity
Haddad CS,Bhattacharya P,Alharshawi K,Marinelarena A,Kumar P,El-Sayed O,Elshabrawy HA,Epstein AL,Prabhakar BS
Published figure using IFN gamma monoclonal antibody (Product # 45-7311-82) in Flow Cytometry
Mon Aug 01 00:00:00 EDT 2016
Heterologous Immunity between Adenoviruses and Hepatitis C Virus: A New Paradigm in HCV Immunity and Vaccines.
PloS one
Singh S,Vedi S,Samrat SK,Li W,Kumar R,Agrawal B
Published figure using IFN gamma monoclonal antibody (Product # 45-7311-82) in Flow Cytometry
Tue Jul 19 00:00:00 EDT 2016
Protective efficacy of the chimeric Staphylococcus aureus vaccine candidate IC in sepsis and pneumonia models.
Scientific reports
Yang L,Cai C,Feng Q,Shi Y,Zuo Q,Yang H,Jing H,Wei C,Zhuang Y,Zou Q,Zeng H
Published figure using IFN gamma monoclonal antibody (Product # 45-7311-82) in Flow Cytometry
Thu Feb 11 00:00:00 EST 2016
Reprogramming the immunological microenvironment through radiation and targeting Axl.
Nature communications
Aguilera TA,Rafat M,Castellini L,Shehade H,Kariolis MS,Hui AB,Stehr H,von Eyben R,Jiang D,Ellies LG,Koong AC,Diehn M,Rankin EB,Graves EE,Giaccia AJ
Published figure using IFN gamma monoclonal antibody (Product # 45-7311-82) in Flow Cytometry
Fri Dec 23 00:00:00 EST 2016
IL-15-dependent balance between Foxp3 and RORγt expression impacts inflammatory bowel disease.
Nature communications
Tosiek MJ,Fiette L,El Daker S,Eberl G,Freitas AA
Published figure using IFN gamma monoclonal antibody (Product # 45-7311-82) in Flow Cytometry
Fri Mar 11 00:00:00 EST 2016
Itk is required for Th9 differentiation via TCR-mediated induction of IL-2 and IRF4.
Nature communications
Gomez-Rodriguez J,Meylan F,Handon R,Hayes ET,Anderson SM,Kirby MR,Siegel RM,Schwartzberg PL
45-7311 was used in Flow cytometry/Cell sorting to investigate the role of IL-9 in allergic asthma and autoimmunity, showing that Itk is required for Th9 differentiation via TCR-mediated induction of IL-2 and IRF4.
Thu Mar 03 00:00:00 EST 2016
NK cell development requires Tsc1-dependent negative regulation of IL-15-triggered mTORC1 activation.
Nature communications
Yang M,Chen S,Du J,He J,Wang Y,Li Z,Liu G,Peng W,Zeng X,Li D,Xu P,Guo W,Chang Z,Wang S,Tian Z,Dong Z
Published figure using IFN gamma monoclonal antibody (Product # 45-7311-82) in Flow Cytometry
Wed Sep 07 00:00:00 EDT 2016
Mycobacterium tuberculosis multistage antigens confer comprehensive protection against pre- and post-exposure infections by driving Th1-type T cell immunity.
Oncotarget
Ma J,Tian M,Fan X,Yu Q,Jing Y,Wang W,Li L,Zhou Z
45-7311 was used in Flow cytometry/Cell sorting to suggest that multistage-specific antigens could be targets for the next generation TB vaccine.
Tue Sep 27 00:00:00 EDT 2016
Agonist anti-GITR monoclonal antibody and stereotactic radiation induce immune-mediated survival advantage in murine intracranial glioma.
Journal for immunotherapy of cancer
Patel MA,Kim JE,Theodros D,Tam A,Velarde E,Kochel CM,Francica B,Nirschl TR,Ghasemzadeh A,Mathios D,Harris-Bookman S,Jackson CC,Jackson C,Ye X,Tran PT,Tyler B,Coric V,Selby M,Brem H,Drake CG,Pardoll DM,Lim M
Published figure using IFN gamma monoclonal antibody (Product # 45-7311-82) in Flow Cytometry
Wed May 18 00:00:00 EDT 2016
Drug-based modulation of endogenous stem cells promotes functional remyelination in vivo.
Nature
Najm FJ,Madhavan M,Zaremba A,Shick E,Karl RT,Factor DC,Miller TE,Nevin ZS,Kantor C,Sargent A,Quick KL,Schlatzer DM,Tang H,Papoian R,Brimacombe KR,Shen M,Boxer MB,Jadhav A,Robinson AP,Podojil JR,Miller SD,Miller RH,Tesar PJ
45-7311 was used in Flow cytometry/Cell sorting to study the drug-based modulation of endogenous stem cells which promotes functional remyelination in vivo.
Thu Jun 11 00:00:00 EDT 2015
Identification of natural RORγ ligands that regulate the development of lymphoid cells.
Cell metabolism
Santori FR,Huang P,van de Pavert SA,Douglass EF,Leaver DJ,Haubrich BA,Keber R,Lorbek G,Konijn T,Rosales BN,Rozman D,Horvat S,Rahier A,Mebius RE,Rastinejad F,Nes WD,Littman DR
Published figure using IFN gamma monoclonal antibody (Product # 45-7311-82) in Flow Cytometry
Tue Feb 03 00:00:00 EST 2015
MHC-mismatched mixed chimerism augments thymic regulatory T-cell production and prevents relapse of EAE in mice.
Proceedings of the National Academy of Sciences of the United States of America
Wu L,Li N,Zhang M,Xue SL,Cassady K,Lin Q,Riggs AD,Zeng D
Published figure using IFN gamma monoclonal antibody (Product # 45-7311-82) in Flow Cytometry
Tue Dec 29 00:00:00 EST 2015
Single-Dose CpG Immunization Protects Against a Heterosubtypic Challenge and Generates Antigen-Specific Memory T Cells.
Frontiers in immunology
Vogel AJ,Brown DM
Published figure using IFN gamma monoclonal antibody (Product # 45-7311-82) in Flow Cytometry
Fri Jul 10 00:00:00 EDT 2015
Activated NKT cells imprint NK-cell differentiation, functionality and education.
European journal of immunology
Riese P,Trittel S,May T,Cicin-Sain L,Chambers BJ,Guzmán CA
45-7311 was used in Flow cytometry/Cell sorting to study the cellular cross-talk between natural killer T cells and natural killer cells.
Mon Jun 01 00:00:00 EDT 2015
Leptin receptor signaling in T cells is required for Th17 differentiation.
Journal of immunology (Baltimore, Md. : 1950)
Reis BS,Lee K,Fanok MH,Mascaraque C,Amoury M,Cohn LB,Rogoz A,Dallner OS,Moraes-Vieira PM,Domingos AI,Mucida D
Published figure using IFN gamma monoclonal antibody (Product # 45-7311-82) in Flow Cytometry
Mon Jun 01 00:00:00 EDT 2015
A tumor lysate is an effective vaccine antigen for the stimulation of CD4(+) T-cell function and subsequent induction of antitumor immunity mediated by CD8(+) T cells.
Cancer biology & therapy
Kawahara M,Takaku H
Published figure using IFN gamma monoclonal antibody (Product # 45-7311-82) in Flow Cytometry
Mon Sep 12 00:00:00 EDT 2016
Adjuvants may reduce in vivo transfection levels for DNA vaccination in mice leading to reduced antigen-specific CD8+ T cell responses.
Human vaccines & immunotherapeutics
Rose AH,Hoffmann FW,Hara JH,Urschitz J,Moisyadi S,Hoffmann PR,Bertino P
Published figure using IFN gamma monoclonal antibody (Product # 45-7311-82) in Flow Cytometry
Mon May 16 00:00:00 EDT 2016
Inadequate activation of the HBsAg-specific Th cells by APCs leads to hyporesponsiveness to HBsAg vaccine in B10.S mice.
Human vaccines & immunotherapeutics
Li X,Xu J,Lv Z,Wang J,Sun S,Zhu W,Wang B,He R,Qu D
Published figure using IFN gamma monoclonal antibody (Product # 45-7311-82) in Flow Cytometry
Tue Apr 19 00:00:00 EDT 2016
Immunogenicity and protective efficacy of DMT liposome-adjuvanted tuberculosis subunit CTT3H vaccine.
Human vaccines & immunotherapeutics
Teng X,Tian M,Li J,Tan S,Yuan X,Yu Q,Jing Y,Zhang Z,Yue T,Zhou L,Fan X
Published figure using IFN gamma monoclonal antibody (Product # 45-7311-82) in Flow Cytometry
Fri Mar 11 00:00:00 EST 2016
Enhanced T-cell activation and differentiation in lymphocytes from transgenic mice expressing ubiquitination-resistant 2KR LAT molecules.
Gene therapy
Rodriguez-Peña AB,Gomez-Rodriguez J,Kortum RL,Palmer DC,Yu Z,Guittard GC,Wohlfert EA,Silver PB,Misplon JA,Sommers CL,Feigenbaum L,Epstein SL,Caspi RR,Belkaid Y,Restifo NP,Samelson LE,Balagopalan L
Published figure using IFN gamma monoclonal antibody (Product # 45-7311-82) in Flow Cytometry
Thu Oct 01 00:00:00 EDT 2015
BTLA associates with increased Foxp3 expression in CD4(+) T cells in dextran sulfate sodium-induced colitis.
International journal of clinical and experimental pathology
Zhang HX,Zhu B,Fu XX,Zeng JC,Zhang JA,Wang WD,Kong B,Xiang WY,Zhong J,Wang CY,Zheng XB,Xu JF
45-7311 was used in Flow cytometry/Cell sorting to study the role of BLTA in ulcerative colitis, showing that the frequency Foxp3-expressing BLTA+CD4(+) T cells from the lamina propria was higher in mice with colitis, and treatment downregulated Foxp3 and IL-17 in BTLA+ cells.
Tue Mar 01 00:00:00 EST 2016
Protection against Mycobacterium tuberculosis infection offered by a new multistage subunit vaccine correlates with increased number of IFN-γ+ IL-2+ CD4+ and IFN-γ+ CD8+ T cells.
PloS one
Wang X,Zhang J,Liang J,Zhang Y,Teng X,Yuan X,Fan X
45-7311 was used in Flow cytometry/Cell sorting to investigate protein subunit vaccinations for control of tuberculosis, showing that a new multistage subunit vaccine increases numbers of T cells and protects against TB.
Wed Mar 09 00:00:00 EST 2016
The Nuclear Orphan Receptor NR2F6 Is a Central Checkpoint for Cancer Immune Surveillance.
Cell reports
Hermann-Kleiter N,Klepsch V,Wallner S,Siegmund K,Klepsch S,Tuzlak S,Villunger A,Kaminski S,Pfeifhofer-Obermair C,Gruber T,Wolf D,Baier G
Published figure using IFN gamma monoclonal antibody (Product # 45-7311-82) in Flow Cytometry
Tue Sep 29 00:00:00 EDT 2015
Near-infrared photoactivatable control of Ca(2+) signaling and optogenetic immunomodulation.
eLife
He L,Zhang Y,Ma G,Tan P,Li Z,Zang S,Wu X,Jing J,Fang S,Zhou L,Wang Y,Huang Y,Hogan PG,Han G,Zhou Y
Published figure using IFN gamma monoclonal antibody (Product # 45-7311-82) in Flow Cytometry
Tue Dec 08 00:00:00 EST 2015
Near-infrared photoactivatable control of Ca(2+) signaling and optogenetic immunomodulation.
eLife
He L,Zhang Y,Ma G,Tan P,Li Z,Zang S,Wu X,Jing J,Fang S,Zhou L,Wang Y,Huang Y,Hogan PG,Han G,Zhou Y
Published figure using IFN gamma monoclonal antibody (Product # 45-7311-82) in Flow Cytometry
Tue Dec 08 00:00:00 EST 2015
A Multiple Antigenic Peptide Mimicking Peptidoglycan Induced T Cell Responses to Protect Mice from Systemic Infection with Staphylococcus aureus.
PloS one
Wang XY,Huang ZX,Chen YG,Lu X,Zhu P,Wen K,Fu N,Liu BY
Published figure using IFN gamma monoclonal antibody (Product # 45-7311-82) in Flow Cytometry
Tue May 24 00:00:00 EDT 2016
Natural Killer Cells Mediate Protection against Yersinia pseudotuberculosis in the Mesenteric Lymph Nodes.
PloS one
Rosenheinrich M,Heine W,Schmühl CM,Pisano F,Dersch P
45-7311 was used in Flow cytometry/Cell sorting to characterise the role of natural killer cells in the response to the extracellular bacterial pathogen, yersiniae.
Tue May 10 00:00:00 EDT 2016
Immunosurveillance by antiangiogenesis: tumor growth arrest by T cell-derived thrombospondin-1.
Cancer research
Schadler KL,Crosby EJ,Zhou AY,Bhang DH,Braunstein L,Baek KH,Crawford D,Crawford A,Angelosanto J,Wherry EJ,Ryeom S
Published figure using IFN gamma monoclonal antibody (Product # 45-7311-82) in Flow Cytometry
Tue Apr 15 00:00:00 EDT 2014
Alphavirus-based vaccines encoding nonstructural proteins of hepatitis C virus induce robust and protective T-cell responses.
Molecular therapy : the journal of the American Society of Gene Therapy
Ip PP,Boerma A,Regts J,Meijerhof T,Wilschut J,Nijman HW,Daemen T
45-7311 was used in Flow cytometry/Cell sorting to study an rSFV-based vector which induces robust T-cell activity and has a potential for the treatment of HCV infections.
Tue Apr 01 00:00:00 EDT 2014
TLR2 engagement on CD4(+) T cells enhances effector functions and protective responses to Mycobacterium tuberculosis.
European journal of immunology
Reba SM,Li Q,Onwuzulike S,Ding X,Karim AF,Hernandez Y,Fulton SA,Harding CV,Lancioni CL,Nagy N,Rodriguez ME,Wearsch PA,Rojas RE
Published figure using IFN gamma monoclonal antibody (Product # 45-7311-82) in Flow Cytometry
Thu May 01 00:00:00 EDT 2014
CD40 ligand preferentially modulates immune response and enhances protection against influenza virus.
Journal of immunology (Baltimore, Md. : 1950)
Hashem AM,Gravel C,Chen Z,Yi Y,Tocchi M,Jaentschke B,Fan X,Li C,Rosu-Myles M,Pereboev A,He R,Wang J,Li X
45-7311 was used in Flow cytometry/Cell sorting to characterise an increased in vivo load of CD40-targeted Ag upon the secretion of the NP-CD40L fusion protein from adenovirus-infected cells.
Tue Jul 15 00:00:00 EDT 2014
Macrophage migration inhibitory factor triggers chemotaxis of CD74+CXCR2+ NKT cells in chemically induced IFN-γ-mediated skin inflammation.
Journal of immunology (Baltimore, Md. : 1950)
Hsieh CY,Chen CL,Lin YS,Yeh TM,Tsai TT,Hong MY,Lin CF
45-7311 was used in Flow cytometry/Cell sorting to hypothesize that MIF triggers an initial step in the chemotaxis of IFN-γ-producing cells in chemically induced skin inflammation.
Wed Oct 01 00:00:00 EDT 2014
Nizatidine, a small molecular compound, enhances killed H5N1 vaccine cell-mediated responses and protects mice from lethal viral challenge.
Human vaccines & immunotherapeutics
Wang S,Wu B,Xue J,Wang M,Chen R,Wang B
Published figure using IFN gamma monoclonal antibody (Product # 45-7311-82) in Flow Cytometry
Mon Jan 05 00:00:00 EST 2015
Myelin-specific T helper 17 cells promote adult hippocampal neurogenesis through indirect mechanisms.
F1000Research
Niebling J,E Rünker A,Schallenberg S,Kretschmer K,Kempermann G
Published figure using IFN gamma monoclonal antibody (Product # 45-7311-82) in Flow Cytometry
Fri Mar 06 00:00:00 EST 2020
Sequential transcriptional changes dictate safe and effective antigen-specific immunotherapy.
Nature communications
Burton BR,Britton GJ,Fang H,Verhagen J,Smithers B,Sabatos-Peyton CA,Carney LJ,Gough J,Strobel S,Wraith DC
45-7311 was used in Flow cytometry/Cell sorting to study the markers significant for antigen-specific immunotherapy such as regulatory CD4(+) T-cell transcription factors.
Wed Sep 03 00:00:00 EDT 2014
Mutual expression of the transcription factors Runx3 and ThPOK regulates intestinal CD4⁺ T cell immunity.
Nature immunology
Reis BS,Rogoz A,Costa-Pinto FA,Taniuchi I,Mucida D
Published figure using IFN gamma monoclonal antibody (Product # 45-7311-82) in Flow Cytometry
Fri Mar 01 00:00:00 EST 2013
Antiapoptotic Mcl-1 is critical for the survival and niche-filling capacity of Foxp3⁺ regulatory T cells.
Nature immunology
Pierson W,Cauwe B,Policheni A,Schlenner SM,Franckaert D,Berges J,Humblet-Baron S,Schönefeldt S,Herold MJ,Hildeman D,Strasser A,Bouillet P,Lu LF,Matthys P,Freitas AA,Luther RJ,Weaver CT,Dooley J,Gray DH,Liston A
45-7311 was used in Flow cytometry/Cell sorting to study the regulation of the Foxp3+ T cell pool by proliferation and apoptosis, and specifically the role of antiapoptoic Mcl-1 in T cell survival.
Sun Sep 01 00:00:00 EDT 2013
Diesel exhaust particle induction of IL-17A contributes to severe asthma.
The Journal of allergy and clinical immunology
Brandt EB,Kovacic MB,Lee GB,Gibson AM,Acciani TH,Le Cras TD,Ryan PH,Budelsky AL,Khurana Hershey GK
45-7311 was used in Flow cytometry/Cell sorting to determine the mechanism by which diesel exhaust particles affect asthma severity, showing that diesel exhaust particles increase airway responsiveness to house dust mite extract due to increased levels of IL-17A, suggesting neutralisation of IL-17A could be used as a future therapy.
Fri Nov 01 00:00:00 EDT 2013
Genetic deletion of chemokine receptor Ccr7 exacerbates atherogenesis in ApoE-deficient mice.
Cardiovascular research
Wan W,Lionakis MS,Liu Q,Roffê E,Murphy PM
Published figure using IFN gamma monoclonal antibody (Product # 45-7311-82) in Flow Cytometry
Fri Mar 01 00:00:00 EST 2013
Steroidogenic enzyme Cyp11a1 regulates Type 2 CD8+ T cell skewing in allergic lung disease.
Proceedings of the National Academy of Sciences of the United States of America
Jia Y,Domenico J,Takeda K,Han J,Wang M,Armstrong M,Reisdorph N,O'Connor BP,Lucas JJ,Gelfand EW
45-7311 was used in Flow cytometry/Cell sorting to demonstrate that Cyp11a1 controls the phenotypic conversion of CD8+ T-cells from IFN-γ to IL-13 production.
Tue May 14 00:00:00 EDT 2013
Double deficiency in IL-17 and IFN-γ signalling significantly suppresses the development of diabetes in the NOD mouse.
Diabetologia
Kuriya G,Uchida T,Akazawa S,Kobayashi M,Nakamura K,Satoh T,Horie I,Kawasaki E,Yamasaki H,Yu L,Iwakura Y,Sasaki H,Nagayama Y,Kawakami A,Abiru N
45-7311 was used in Flow cytometry/Cell sorting to study the suppression of diabetes in NOD mice due to IL-17 and IFN-γ deficiency.
Thu Aug 01 00:00:00 EDT 2013
Regulatory T cells prevent Th2 immune responses and pulmonary eosinophilia during respiratory syncytial virus infection in mice.
Journal of virology
Durant LR,Makris S,Voorburg CM,Loebbermann J,Johansson C,Openshaw PJ
45-7311 was used in Flow cytometry/Cell sorting to provide evidence that dysregulation of normal immune responses to viral infection may contribute to severe respiratory viral disease.
Tue Oct 01 00:00:00 EDT 2013
Interleukin-22 as a molecular adjuvant facilitates IL-17-producing CD8+ T cell responses against a HBV DNA vaccine in mice.
Human vaccines & immunotherapeutics
Wu B,Zou Q,Hu Y,Wang B
Published figure using IFN gamma monoclonal antibody (Product # 45-7311-82) in Flow Cytometry
Tue Oct 01 00:00:00 EDT 2013
Enhanced Delivery and Potency of Self-Amplifying mRNA Vaccines by Electroporation in Situ.
Vaccines
Cu Y,Broderick KE,Banerjee K,Hickman J,Otten G,Barnett S,Kichaev G,Sardesai NY,Ulmer JB,Geall A
45-7311 was used in Flow cytometry/Cell sorting to demonstrate that electroporation delivery of self-amplifying mRNA elicits a strong and broad immune response in mice.
Thu Aug 22 00:00:00 EDT 2013
The cytokines interleukin 27 and interferon-γ promote distinct Treg cell populations required to limit infection-induced pathology.
Immunity
Hall AO,Beiting DP,Tato C,John B,Oldenhove G,Lombana CG,Pritchard GH,Silver JS,Bouladoux N,Stumhofer JS,Harris TH,Grainger J,Wojno ED,Wagage S,Roos DS,Scott P,Turka LA,Cherry S,Reiner SL,Cua D,Belkaid Y,Elloso MM,Hunter CA
45-7311 was used in Flow cytometry/Cell sorting to study the promotion of distinct Treg cell populations by the cytokines IL-27 and IFN-y, and the role they play in limiting infection induced pathology.
Fri Sep 21 00:00:00 EDT 2012
Increased protection from vaccinia virus infection in mice genetically prone to lymphoproliferative disorders.
Journal of virology
Seedhom MO,Mathurin KS,Kim SK,Welsh RM
Published figure using IFN gamma monoclonal antibody (Product # 45-7311-82) in Flow Cytometry
Fri Jun 01 00:00:00 EDT 2012
Treatment with targeted vesicular stomatitis virus generates therapeutic multifunctional anti-tumor memory CD4 T cells.
Cancer gene therapy
Gao Y,Whitaker-Dowling P,Griffin JA,Bergman I
Published figure using IFN gamma monoclonal antibody (Product # 45-7311-82) in Flow Cytometry
Sun Apr 01 00:00:00 EDT 2012
Epithelial cell-intrinsic Notch signaling plays an essential role in the maintenance of gut immune homeostasis.
Journal of immunology (Baltimore, Md. : 1950)
Obata Y,Takahashi D,Ebisawa M,Kakiguchi K,Yonemura S,Jinnohara T,Kanaya T,Fujimura Y,Ohmae M,Hase K,Ohno H
45-7311 was used in Flow cytometry/Cell sorting to demonstrate that mice with an IEC-specific deletion in a TF that mediates Notch signalling spontaneously develop colitis.
Thu Mar 01 00:00:00 EST 2012
Protective role for TLR4 signaling in atherosclerosis progression as revealed by infection with a common oral pathogen.
Journal of immunology (Baltimore, Md. : 1950)
Hayashi C,Papadopoulos G,Gudino CV,Weinberg EO,Barth KR,Madrigal AG,Chen Y,Ning H,LaValley M,Gibson FC,Hamilton JA,Genco CA
Published figure using IFN gamma monoclonal antibody (Product # 45-7311-82) in Flow Cytometry
Mon Oct 01 00:00:00 EDT 2012
Evaluation of Lassa virus vaccine immunogenicity in a CBA/J-ML29 mouse model.
Vaccine
Goicochea MA,Zapata JC,Bryant J,Davis H,Salvato MS,Lukashevich IS
Published figure using IFN gamma monoclonal antibody (Product # 45-7311-82) in Flow Cytometry
Tue Feb 14 00:00:00 EST 2012
Soluble MOG35-55/I-A(b) dimers ameliorate experimental autoimmune encephalomyelitis by reducing encephalitogenic T cells.
PloS one
Gong Y,Wang Z,Liang Z,Duan H,Ouyang L,Yu Q,Xu Z,Shen G,Weng X,Wu X
Published figure using IFN gamma monoclonal antibody (Product # 45-7311-82) in Flow Cytometry
Fri Jul 19 00:00:00 EDT 2013
Distinct MHC class I-dependent NK cell-activating receptors control cytomegalovirus infection in different mouse strains.
The Journal of experimental medicine
Pyzik M,Charbonneau B,Gendron-Pontbriand EM,Babić M,Krmpotić A,Jonjić S,Vidal SM
45-7311 was used in Flow cytometry/Cell sorting to study how multiple activating Ly49 receptors may participate in H-2-dependent recognition of MCMV infection, providing a common mechanism of NK cell-mediated resistance against viral infection.
Mon May 09 00:00:00 EDT 2011
Virulence of Toxoplasma gondii is associated with distinct dendritic cell responses and reduced numbers of activated CD8+ T cells.
Journal of immunology (Baltimore, Md. : 1950)
Tait ED,Jordan KA,Dupont CD,Harris TH,Gregg B,Wilson EH,Pepper M,Dzierszinski F,Roos DS,Hunter CA
45-7311 was used in Flow cytometry/Cell sorting to show the dendritic cell response to T.gondii alters levels of CD8+ T cells which ultimately determine the outcome of infection.
Sun Aug 01 00:00:00 EDT 2010
Down-regulation of Gfi-1 expression by TGF-beta is important for differentiation of Th17 and CD103+ inducible regulatory T cells.
The Journal of experimental medicine
Zhu J,Davidson TS,Wei G,Jankovic D,Cui K,Schones DE,Guo L,Zhao K,Shevach EM,Paul WE
45-7311 was used in Flow cytometry/Cell sorting to show that Gfi-1, a transcriptional repressor, has a critical role in enhancing Th2 cell expansion and repressing induction of Th17 and CD103(+) iTreg cells.
Mon Feb 16 00:00:00 EST 2009
Th17 cells undergo Fas-mediated activation-induced cell death independent of IFN-gamma.
Journal of immunology (Baltimore, Md. : 1950)
Zhang Y,Xu G,Zhang L,Roberts AI,Shi Y
Tue Jul 01 00:00:00 EDT 2008
T cell acquisition of APC membrane can impact interpretation of adoptive transfer experiments using CD45 congenic mouse strains.
Journal of immunological methods
Cho KS,Hill AB
Thu Jan 31 00:00:00 EST 2008
IL-6-dependent and -independent pathways in the development of interleukin 17-producing T helper cells.
Proceedings of the National Academy of Sciences of the United States of America
Kimura A,Naka T,Kishimoto T
Published figure using IFN gamma monoclonal antibody (Product # 45-7311-82) in Flow Cytometry
Tue Jul 17 00:00:00 EDT 2007
IFN-gamma decreases CTL generation by limiting IL-2 production: A feedback loop controlling effector cell production.
American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons
Hidalgo LG,Urmson J,Halloran PF
Fri Apr 01 00:00:00 EST 2005
