Product References
Self-amplifying mRNA seasonal influenza vaccines elicit mouse neutralizing antibody and cell-mediated immunity and protect ferrets.
NPJ vaccines
Cheung M,Chang C,Rathnasinghe R,Rossignol E,Zhang Y,Ferrari A,Patel H,Huang Y,Sanchez Guillen M,Scalzo T,Lee C,Otten GR,Settembre EC,Music N,Palladino G,Wen Y
Published figure using IL-13 monoclonal antibody (Product # 53-7133-82) in Flow Cytometry
Wed Oct 04 00:00:00 EDT 2023
Monitoring Group 2 Innate Lymphoid Cell Biology in Models of Lung Inflammation.
Bio-protocol
Badrani JH,Strohm AN,Haung YA,Doherty TA
Published figure using IL-13 monoclonal antibody (Product # 53-7133-82) in Flow Cytometry
Thu Jul 20 00:00:00 EDT 2023
Fibroblastic reticular cells in lymph node potentiate white adipose tissue beiging through neuro-immune crosstalk in male mice.
Nature communications
Cheong LY,Wang B,Wang Q,Jin L,Kwok KHM,Wu X,Shu L,Lin H,Chung SK,Cheng KKY,Hoo RLC,Xu A
Published figure using IL-13 monoclonal antibody (Product # 53-7133-82) in Flow Cytometry
Fri Mar 03 00:00:00 EST 2023
Calcaratarin D, a labdane diterpenoid, attenuates mouse asthma via modulating alveolar macrophage function.
British journal of pharmacology
Liao W,Foo HYC,Tran TNQ,Chai CLL,Wong WSF
Published figure using IL-13 monoclonal antibody (Product # 53-7133-82) in Flow Cytometry
Sat Apr 01 00:00:00 EDT 2023
Altering the mRNA-1273 dosing interval impacts the kinetics, quality, and magnitude of immune responses in mice.
Frontiers in immunology
Garcia-Dominguez D,Henry C,Ma L,Jani H,Amato NJ,Manning T,Freyn A,Davis H,Hsiao CJ,Li M,Koch H,Elbashir S,DiPiazza A,Carfi A,Edwards D,Bahl K
53-7133-82 was used in flow cytometry to study how in a non-pandemic setting, a longer interval (=6 weeks) between the doses of the primary series for mRNA-1273 may induce more durable immune responses.
Mon Nov 28 00:00:00 EST 2022
Mitochondrial transcription factor A in RORγt+ lymphocytes regulate small intestine homeostasis and metabolism.
Nature communications
Fu Z,Dean JW,Xiong L,Dougherty MW,Oliff KN,Chen ZE,Jobin C,Garrett TJ,Zhou L
53-7133-82 was used in Flow Cytometry to show that IL-22, a cytokine produced by RORγt+ lymphocytes inhibits IL-13-induced tuft cell differentiation in vitro, and suppresses the tuft cell-type 2 immune circuit and small intestine lengthening in vivo, highlighting its key role in gut tissue remodeling.
Thu Jul 22 00:00:00 EDT 2021
Mitochondrial transcription factor A in RORγt+ lymphocytes regulate small intestine homeostasis and metabolism.
Nature communications
Fu Z,Dean JW,Xiong L,Dougherty MW,Oliff KN,Chen ZE,Jobin C,Garrett TJ,Zhou L
53-7133-82 was used in Flow Cytometry to show that IL-22, a cytokine produced by RORγt+ lymphocytes inhibits IL-13-induced tuft cell differentiation in vitro, and suppresses the tuft cell-type 2 immune circuit and small intestine lengthening in vivo, highlighting its key role in gut tissue remodeling.
Thu Jul 22 00:00:00 EDT 2021
Synergistic effect of non-neutralizing antibodies and interferon-γ for cross-protection against influenza.
iScience
Shibuya M,Tamiya S,Kawai A,Hirai T,Cragg MS,Yoshioka Y
Published figure using IL-13 monoclonal antibody (Product # 53-7133-82) in ELISA
Fri Oct 22 00:00:00 EDT 2021
Synergistic effect of non-neutralizing antibodies and interferon-γ for cross-protection against influenza.
iScience
Shibuya M,Tamiya S,Kawai A,Hirai T,Cragg MS,Yoshioka Y
Published figure using IL-13 monoclonal antibody (Product # 53-7133-82) in ELISA
Fri Oct 22 00:00:00 EDT 2021
Type 1 Cytotoxic T Cells Increase in Placenta after Intrauterine Inflammation.
Frontiers in immunology
Liu J,Liu Y,Panda S,Liu A,Lei J,Burd I
Published figure using IL-13 monoclonal antibody (Product # 53-7133-82) in Flow Cytometry
Fri Dec 17 00:00:00 EST 2021
Gut Microbial Metabolite Pravastatin Attenuates Intestinal Ischemia/Reperfusion Injury Through Promoting IL-13 Release From Type II Innate Lymphoid Cells via IL-33/ST2 Signaling.
Frontiers in immunology
Deng F,Hu JJ,Yang X,Sun QS,Lin ZB,Zhao BC,Yao ZW,Luo SD,Chen ZL,Liu Y,Yan ZZ,Li C,Liu WF,Liu KX
Published figure using IL-13 monoclonal antibody (Product # 53-7133-82) in Flow Cytometry
Tue Dec 21 00:00:00 EST 2021
Gut Microbial Metabolite Pravastatin Attenuates Intestinal Ischemia/Reperfusion Injury Through Promoting IL-13 Release From Type II Innate Lymphoid Cells via IL-33/ST2 Signaling.
Frontiers in immunology
Deng F,Hu JJ,Yang X,Sun QS,Lin ZB,Zhao BC,Yao ZW,Luo SD,Chen ZL,Liu Y,Yan ZZ,Li C,Liu WF,Liu KX
Published figure using IL-13 monoclonal antibody (Product # 53-7133-82) in Flow Cytometry
Tue Dec 21 00:00:00 EST 2021
6-Phosphogluconate dehydrogenase (6PGD), a key checkpoint in reprogramming of regulatory T cells metabolism and function.
eLife
Daneshmandi S,Cassel T,Higashi RM,Fan TW,Seth P
Published figure using IL-13 monoclonal antibody (Product # 53-7133-82) in Flow Cytometry
Thu Oct 28 00:00:00 EDT 2021
ILC3s control airway inflammation by limiting T cell responses to allergens and microbes.
Cell reports
Teng F,Tachó-Piñot R,Sung B,Farber DL,Worgall S,Hammad H,Lambrecht BN,Hepworth MR,Sonnenberg GF
53-7133-82 was used in Flow cytometry/Cell sorting to demonstrate a critical role for antigen-presenting ILC3s in orchestrating immune tolerance in the airway by restricting pro-inflammatory T cell responses to both allergens and microbes.
Tue Nov 23 00:00:00 EST 2021
A booster dose enhances immunogenicity of the COVID-19 vaccine candidate ChAdOx1 nCoV-19 in aged mice.
Med (New York, N.Y.)
Silva-Cayetano A,Foster WS,Innocentin S,Belij-Rammerstorfer S,Spencer AJ,Burton OT,Fra-Bidó S,Le Lee J,Thakur N,Conceicao C,Wright D,Barrett J,Evans-Bailey N,Noble C,Bailey D,Liston A,Gilbert SC,Lambe T,Linterman MA
53-7133-82 was used in Flow Cytometry to show that ChAdOx1 nCoV-19 induces both cellular and humoral immunity in adult and aged mice and suggest a prime-boost strategy is a rational approach to enhance immunogenicity in older persons.
Fri Mar 12 00:00:00 EST 2021
A helminth-derived suppressor of ST2 blocks allergic responses.
eLife
Vacca F,Chauché C,Jamwal A,Hinchy EC,Heieis G,Webster H,Ogunkanbi A,Sekne Z,Gregory WF,Wear M,Perona-Wright G,Higgins MK,Nys JA,Cohen ES,McSorley HJ
Published figure using IL-13 monoclonal antibody (Product # 53-7133-82) in Flow Cytometry
Mon May 18 00:00:00 EDT 2020
Arf1-mediated lipid metabolism sustains cancer cells and its ablation induces anti-tumor immune responses in mice.
Nature communications
Wang G,Xu J,Zhao J,Yin W,Liu D,Chen W,Hou SX
Published figure using IL-13 monoclonal antibody (Product # 53-7133-82) in Flow Cytometry
Fri Jan 10 00:00:00 EST 2020
Tumors induce de novo steroid biosynthesis in T cells to evade immunity.
Nature communications
Mahata B,Pramanik J,van der Weyden L,Polanski K,Kar G,Riedel A,Chen X,Fonseca NA,Kundu K,Campos LS,Ryder E,Duddy G,Walczak I,Okkenhaug K,Adams DJ,Shields JD,Teichmann SA
53-7133 was used in Flow cytometry/Cell sorting to show that tumors induce de novo steroidogenesis in T lymphocytes to evade anti-tumor immunity.
Fri Jul 17 00:00:00 EDT 2020
Th2 cell-derived IL-4/IL-13 promote ILC2 accumulation in the lung by ILC2-intrinsic STAT6 signaling in mice.
European journal of immunology
Symowski C,Voehringer D
53-7133-82 was used in Flow Cytometry to demonstrate that IL-4/IL-13 secretion from Th2 cells promotes proliferation and expansion of the ILC2 population in the lung of N. brasiliensis-infected mice.
Sun Sep 01 00:00:00 EDT 2019
Costimulation of type-2 innate lymphoid cells by GITR promotes effector function and ameliorates type 2 diabetes.
Nature communications
Galle-Treger L,Sankaranarayanan I,Hurrell BP,Howard E,Lo R,Maazi H,Lewis G,Banie H,Epstein AL,Hu P,Rehan VK,Gilliland FD,Allayee H,Soroosh P,Sharpe AH,Akbari O
Published figure using IL-13 monoclonal antibody (Product # 53-7133-82) in Flow Cytometry
Tue Feb 12 00:00:00 EST 2019
TNFR2 Signaling Enhances ILC2 Survival, Function, and Induction of Airway Hyperreactivity.
Cell reports
Hurrell BP,Galle-Treger L,Jahani PS,Howard E,Helou DG,Banie H,Soroosh P,Akbari O
Published figure using IL-13 monoclonal antibody (Product # 53-7133-82) in Flow Cytometry
Tue Dec 24 00:00:00 EST 2019
E3 Ligase VHL Promotes Group 2 Innate Lymphoid Cell Maturation and Function via Glycolysis Inhibition and Induction of Interleukin-33 Receptor.
Immunity
Li Q,Li D,Zhang X,Wan Q,Zhang W,Zheng M,Zou L,Elly C,Lee JH,Liu YC
Published figure using IL-13 monoclonal antibody (Product # 53-7133-82) in Flow Cytometry
Tue Feb 20 00:00:00 EST 2018
Autoimmune Th17 Cells Induced Synovial Stromal and Innate Lymphoid Cell Secretion of the Cytokine GM-CSF to Initiate and Augment Autoimmune Arthritis.
Immunity
Hirota K,Hashimoto M,Ito Y,Matsuura M,Ito H,Tanaka M,Watanabe H,Kondoh G,Tanaka A,Yasuda K,Kopf M,Potocnik AJ,Stockinger B,Sakaguchi N,Sakaguchi S
Published figure using IL-13 monoclonal antibody (Product # 53-7133-82) in Flow Cytometry
Tue Jun 19 00:00:00 EDT 2018
Amphiregulin-Producing Pathogenic Memory T Helper 2 Cells Instruct Eosinophils to Secrete Osteopontin and Facilitate Airway Fibrosis.
Immunity
Morimoto Y,Hirahara K,Kiuchi M,Wada T,Ichikawa T,Kanno T,Okano M,Kokubo K,Onodera A,Sakurai D,Okamoto Y,Nakayama T
53-7133-82 was used in Flow Cytometry to find that interleukin-33 (IL-33) enhanced amphiregulin production by the IL-33 receptor, ST2hi memory T helper 2 (Th2) cells.
Tue Jul 17 00:00:00 EDT 2018
Heterologous Prime-Boost Combinations Highlight the Crucial Role of Adjuvant in Priming the Immune System.
Frontiers in immunology
Ciabattini A,Pettini E,Fiorino F,Lucchesi S,Pastore G,Brunetti J,Santoro F,Andersen P,Bracci L,Pozzi G,Medaglini D
53-7133 was used in Flow cytometry/Cell sorting to investigate the impact of heterologous prime-boost approaches on the vaccine-specific cellular and humoral responses specific for a mycobacterial vaccine antigen on C57BL/6 mice.
Mon Apr 08 00:00:00 EDT 2019
Fli1-haploinsufficient dermal fibroblasts promote skin-localized transdifferentiation of Th2-like regulatory T cells.
Arthritis research & therapy
Saigusa R,Asano Y,Taniguchi T,Hirabayashi M,Nakamura K,Miura S,Yamashita T,Takahashi T,Ichimura Y,Toyama T,Yoshizaki A,Trojanowska M,Sato S
Published figure using IL-13 monoclonal antibody (Product # 53-7133-82) in Flow Cytometry
Wed Feb 07 00:00:00 EST 2018
Nematode-Infected Mice Acquire Resistance to Subsequent Infection With Unrelated Nematode by Inducing Highly Responsive Group 2 Innate Lymphoid Cells in the Lung.
Frontiers in immunology
Yasuda K,Adachi T,Koida A,Nakanishi K
Published figure using IL-13 monoclonal antibody (Product # 53-7133-82) in Flow Cytometry
Mon Sep 30 00:00:00 EDT 2019
Genome-wide analyses reveal the IRE1a-XBP1 pathway promotes T helper cell differentiation by resolving secretory stress and accelerating proliferation.
Genome medicine
Pramanik J,Chen X,Kar G,Henriksson J,Gomes T,Park JE,Natarajan K,Meyer KB,Miao Z,McKenzie ANJ,Mahata B,Teichmann SA
Published figure using IL-13 monoclonal antibody (Product # 53-7133-82) in Flow Cytometry
Wed Oct 24 00:00:00 EDT 2018
Bcl11b is essential for licensing Th2 differentiation during helminth infection and allergic asthma.
Nature communications
Lorentsen KJ,Cho JJ,Luo X,Zuniga AN,Urban JF,Zhou L,Gharaibeh R,Jobin C,Kladde MP,Avram D
53-7133 was used in Flow cytometry/Cell sorting to establish novel roles for Bcl11b in the regulatory loop that licenses Th2 program in vivo.
Thu Apr 26 00:00:00 EDT 2018
An ST2-dependent role of bone marrow-derived group 2 innate lymphoid cells in pulmonary fibrosis.
The Journal of pathology
Zhao Y,De Los Santos FG,Wu Z,Liu T,Phan SH
53-7133-82 was used in Flow cytometry/Cell sorting to suggest that the BM-derived ILC2s were recruited to fibrotic lung through the IL-33/ST2 pathway, and contributed to fibroblast activation to promote lung fibrosis.
Wed Aug 01 00:00:00 EDT 2018
Epidermal Growth Factor Receptor Expression Licenses Type-2 Helper T Cells to Function in a T Cell Receptor-Independent Fashion.
Immunity
Minutti CM,Drube S,Blair N,Schwartz C,McCrae JC,McKenzie AN,Kamradt T,Mokry M,Coffer PJ,Sibilia M,Sijts AJ,Fallon PG,Maizels RM,Zaiss DM
Published figure using IL-13 monoclonal antibody (Product # 53-7133-82) in Flow Cytometry
Tue Oct 17 00:00:00 EDT 2017
HpARI Protein Secreted by a Helminth Parasite Suppresses Interleukin-33.
Immunity
Osbourn M,Soares DC,Vacca F,Cohen ES,Scott IC,Gregory WF,Smyth DJ,Toivakka M,Kemter AM,le Bihan T,Wear M,Hoving D,Filbey KJ,Hewitson JP,Henderson H,Gonzàlez-Cìscar A,Errington C,Vermeren S,Astier AL,Wallace WA,Schwarze J,Ivens AC,Maizels RM,McSorley HJ
Published figure using IL-13 monoclonal antibody (Product # 53-7133-82) in Flow Cytometry
Tue Oct 17 00:00:00 EDT 2017
Analyses of a Mutant Foxp3 Allele Reveal BATF as a Critical Transcription Factor in the Differentiation and Accumulation of Tissue Regulatory T Cells.
Immunity
Hayatsu N,Miyao T,Tachibana M,Murakami R,Kimura A,Kato T,Kawakami E,Endo TA,Setoguchi R,Watarai H,Nishikawa T,Yasuda T,Yoshida H,Hori S
53-7133-82 was used in Flow Cytometry to identify BATF as a regulator of tissue regulatory T (Treg) cells and suggest that sequence-specific perturbations of Foxp3-DNA interactions can influence specific facets of Treg physiology and the immunopathologies.
Tue Aug 15 00:00:00 EDT 2017
Intestinal helminth infection induces highly functional resident memory CD4+ T cells in mice.
European journal of immunology
Steinfelder S,Rausch S,Michael D,Kühl AA,Hartmann S
Wed Feb 01 00:00:00 EST 2017
Extrafollicular CD4+ T-B interactions are sufficient for inducing autoimmune-like chronic graft-versus-host disease.
Nature communications
Deng R,Hurtz C,Song Q,Yue C,Xiao G,Yu H,Wu X,Muschen M,Forman S,Martin PJ,Zeng D
Published figure using IL-13 monoclonal antibody (Product # 53-7133-82) in Flow Cytometry
Tue Oct 17 00:00:00 EDT 2017
Toxoplasma Co-infection Prevents Th2 Differentiation and Leads to a Helminth-Specific Th1 Response.
Frontiers in cellular and infection microbiology
Ahmed N,French T,Rausch S,Kühl A,Hemminger K,Dunay IR,Steinfelder S,Hartmann S
53-7133 was used in Flow cytometry/Cell sorting to conclude a previous T. gondii infection limits a helminth-specific Th2 immune response while promoting a shift toward a Th1-type immune response.
Mon Apr 02 00:00:00 EDT 2018
Th2/1 Hybrid Cells Occurring in Murine and Human Strongyloidiasis Share Effector Functions of Th1 Cells.
Frontiers in cellular and infection microbiology
Bock CN,Babu S,Breloer M,Rajamanickam A,Boothra Y,Brunn ML,Kühl AA,Merle R,Löhning M,Hartmann S,Rausch S
53-7133 was used in Flow cytometry/Cell sorting to assess the T helper cell phenotypes in threadworm-infected patients and experimental murine infections with focus on CD4+ T cells co-expressing markers of Th2 and Th1 differentiation.
Mon Feb 26 00:00:00 EST 2018
IL-33-Dependent Group 2 Innate Lymphoid Cells Promote Cutaneous Wound Healing.
The Journal of investigative dermatology
Rak GD,Osborne LC,Siracusa MC,Kim BS,Wang K,Bayat A,Artis D,Volk SW
53-7133 was used in Flow cytometry/Cell sorting to demonstrate that cutaneous injury promotes an IL-33-dependent group 2 ILC response and that abrogation of this response can impair efficient wound closure.
Mon Feb 01 00:00:00 EST 2016
Induction of Broad-Based Immunity and Protective Efficacy by Self-amplifying mRNA Vaccines Encoding Influenza Virus Hemagglutinin.
Journal of virology
Brazzoli M,Magini D,Bonci A,Buccato S,Giovani C,Kratzer R,Zurli V,Mangiavacchi S,Casini D,Brito LM,De Gregorio E,Mason PW,Ulmer JB,Geall AJ,Bertholet S
53-7133 was used in Flow cytometry/Cell sorting to describe protective immune responses in mice and ferrets after vaccination with a novel HA-based influenza vaccine.
Fri Jan 01 00:00:00 EST 2016
Transcription Factors Oct-1 and GATA-3 Cooperatively Regulate Th2 Cytokine Gene Expression via the RHS5 within the Th2 Locus Control Region.
PloS one
Kim K,Kim N,Lee GR
Published figure using IL-13 monoclonal antibody (Product # 53-7133-82) in Flow Cytometry
Thu Jul 07 00:00:00 EDT 2016
T helper cell IL-4 drives intestinal Th2 priming to oral peanut antigen, under the control of OX40L and independent of innate-like lymphocytes.
Mucosal immunology
Chu DK,Mohammed-Ali Z,Jiménez-Saiz R,Walker TD,Goncharova S,Llop-Guevara A,Kong J,Gordon ME,Barra NG,Gillgrass AE,Van Seggelen H,Khan WI,Ashkar AA,Bramson JL,Humbles AA,Kolbeck R,Waserman S,Jordana M
53-7133 was used in Flow cytometry/Cell sorting to reveal intestinal Th2 priming is initiated by an autocrine/paracrine acting CD4(+) Th cell-intrinsic IL-4 program that is controlled by DC OX40L.
Sat Nov 01 00:00:00 EDT 2014
Type 2 innate lymphoid cells control eosinophil homeostasis.
Nature
Nussbaum JC,Van Dyken SJ,von Moltke J,Cheng LE,Mohapatra A,Molofsky AB,Thornton EE,Krummel MF,Chawla A,Liang HE,Locksley RM
Published figure using IL-13 monoclonal antibody (Product # 53-7133-82) in Flow Cytometry
Thu Oct 10 00:00:00 EDT 2013
IL-33 signaling regulates innate and adaptive immunity to Cryptococcus neoformans.
Journal of immunology (Baltimore, Md. : 1950)
Flaczyk A,Duerr CU,Shourian M,Lafferty EI,Fritz JH,Qureshi ST
53-7133 was used in Flow cytometry/Cell sorting to study how allergic patterns of lung inflammation are mediated as a host response to Cryptococcus neoformans infection.
Sun Sep 01 00:00:00 EDT 2013
Tumor suppressor p53 inhibits systemic autoimmune diseases by inducing regulatory T cells.
Journal of immunology (Baltimore, Md. : 1950)
Kawashima H,Takatori H,Suzuki K,Iwata A,Yokota M,Suto A,Minamino T,Hirose K,Nakajima H
53-7133 was used in Flow cytometry/Cell sorting to investigate how p53 suppresses autoimmunity.
Tue Oct 01 00:00:00 EDT 2013
Bacterial colonization dampens influenza-mediated acute lung injury via induction of M2 alveolar macrophages.
Nature communications
Wang J,Li F,Sun R,Gao X,Wei H,Li LJ,Tian Z
Published figure using IL-13 monoclonal antibody (Product # 53-7133-82) in Neutralization
Mon Dec 30 00:00:00 EST 2013
Lack of IL-4 receptor expression on T helper cells reduces T helper 2 cell polyfunctionality and confers resistance in allergic bronchopulmonary mycosis.
Mucosal immunology
Müller U,Piehler D,Stenzel W,Köhler G,Frey O,Held J,Grahnert A,Richter T,Eschke M,Kamradt T,Brombacher F,Alber G
53-7133 was used in Flow cytometry/Cell sorting to study the function of the interleukin-4 receptor on T helper cells in pulmonary cryptococcosis.
Tue May 01 00:00:00 EDT 2012
