Product References
Engineered bone marrow as a clinically relevant ex vivo model for primary bone cancer research and drug screening.
Proceedings of the National Academy of Sciences of the United States of America
Griffin KH,Thorpe SW,Sebastian A,Hum NR,Coonan TP,Sagheb IS,Loots GG,Randall RL,Leach JK
Published figure using Ly-6A/E (Sca-1) monoclonal antibody (Product # 11-5981-82) in Flow Cytometry
Tue Sep 26 00:00:00 EDT 2023
STS1 and STS2 Phosphatase Inhibitor Baicalein Enhances the Expansion of Hematopoietic and Progenitor Stem Cells and Alleviates 5-Fluorouracil-Induced Myelosuppression.
International journal of molecular sciences
Li N,Wang Y,Wang A,Zhang J,Jia C,Yu C,Song Z,Wang S,Liu L,Yi J,Bao Y,Huang Y,Sun L
Published figure using Ly-6A/E (Sca-1) monoclonal antibody (Product # 11-5981-82) in Flow Cytometry
Fri Feb 03 00:00:00 EST 2023
Polycomb Bodies Detection in Murine Fibromuscular Stroma from Skin, Skeletal Muscles, and Aortic Tissues.
Methods in molecular biology (Clifton, N.J.)
Rosti V,Gorini F,Santarelli P,Sarnicola ML,Magnani S,Lanzuolo C
11-5981-82 was used in Flow cytometry/Cell sorting to combine a fluorescence-activated cell sorter (FACS)-based method with an immunofluorescence staining.
Wed May 24 00:00:00 EDT 2023
CXCL5 suppression recovers neovascularization and accelerates wound healing in diabetes mellitus.
Cardiovascular diabetology
Chen C,Lin LY,Chen JW,Chang TT
11-5981-82 was used in Flow Cytometry to explore the impacts and mechanistic insights of CXCL5 in neovasculogenesis and wound healing in diabetes mellitus.
Fri Jul 07 00:00:00 EDT 2023
The extracellular matrix controls stem cell specification and crypt morphology in the developing and adult mouse gut.
Biology open
Ramadan R,Wouters VM,van Neerven SM,de Groot NE,Garcia TM,Muncan V,Franklin OD,Battle M,Carlson KS,Leach J,Sansom OJ,Boulard O,Chamaillard M,Vermeulen L,Medema JP,Huels DJ
Published figure using Ly-6A/E (Sca-1) monoclonal antibody (Product # 11-5981-82) in Flow Cytometry
Thu Dec 15 00:00:00 EST 2022
The extracellular matrix controls stem cell specification and crypt morphology in the developing and adult mouse gut.
Biology open
Ramadan R,Wouters VM,van Neerven SM,de Groot NE,Garcia TM,Muncan V,Franklin OD,Battle M,Carlson KS,Leach J,Sansom OJ,Boulard O,Chamaillard M,Vermeulen L,Medema JP,Huels DJ
Published figure using Ly-6A/E (Sca-1) monoclonal antibody (Product # 11-5981-82) in Flow Cytometry
Thu Dec 15 00:00:00 EST 2022
Cardiac Mesenchymal Stem Cells Promote Fibrosis and Remodeling in Heart Failure: Role of PDGF Signaling.
JACC. Basic to translational science
Hamid T,Xu Y,Ismahil MA,Rokosh G,Jinno M,Zhou G,Wang Q,Prabhu SD
Published figure using Ly-6A/E (Sca-1) monoclonal antibody (Product # 11-5981-82) in Flow Cytometry
Sun May 01 00:00:00 EDT 2022
Hematopoietic-Mesenchymal Signals Regulate the Properties of Mesenchymal Stem Cells.
International journal of molecular sciences
Kanazawa S,Okada H,Riu D,Mabuchi Y,Akazawa C,Iwata J,Hoshi K,Hikita A
Published figure using Ly-6A/E (Sca-1) monoclonal antibody (Product # 11-5981-82) in Flow Cytometry
Tue Jul 26 00:00:00 EDT 2022
Dynamic and adaptive cancer stem cell population admixture in colorectal neoplasia.
Cell stem cell
Vasquez EG,Nasreddin N,Valbuena GN,Mulholland EJ,Belnoue-Davis HL,Eggington HR,Schenck RO,Wouters VM,Wirapati P,Gilroy K,Lannagan TRM,Flanagan DJ,Najumudeen AK,Omwenga S,McCorry AMB,Easton A,Koelzer VH,East JE,Morton D,Trusolino L,Maughan T,Campbell AD,Loughrey MB,Dunne PD,Tsantoulis P,Huels DJ,Tejpar S,Sansom OJ,Leedham SJ
Published figure using Ly-6A/E (Sca-1) monoclonal antibody (Product # 11-5981-82) in Flow Cytometry
Thu Aug 04 00:00:00 EDT 2022
Is platelet responsiveness to clopidogrel attenuated in overweight or obese patients and why? A reverse translational study in mice.
British journal of pharmacology
Jiang LP,Ji JZ,Ge PX,Zhu T,Mi QY,Tai T,Li YF,Xie HG
11-5981-82 was used in Flow cytometry/Cell sorting to discover whether and why obesity could affect the metabolic activation of and/or platelet response to clopidogrel in obese patients and high-fat diet-induced obese mice.
Sat Jan 01 00:00:00 EST 2022
The microbiota regulates hematopoietic stem cell fate decisions by controlling iron availability in bone marrow.
Cell stem cell
Zhang D,Gao X,Li H,Borger DK,Wei Q,Yang E,Xu C,Pinho S,Frenette PS
11-5981-82 was used in Flow cytometry/Cell sorting to reveal an intricate interplay between the microbiota, macrophages, and iron, and their essential roles in regulating critical HSC fate decisions under stress.
Thu Feb 03 00:00:00 EST 2022
Hematopoietic stem cell transplantation ameliorates maternal diabetes-mediated gastrointestinal symptoms and autism-like behavior in mouse offspring.
Annals of the New York Academy of Sciences
Zeng J,Liang Y,Sun R,Huang S,Wang Z,Xiao L,Lu J,Yu H,Yao P
11-5981-82 was used in Flow cytometry/Cell sorting to conclude that HSCT can ameliorate maternal diabetes-mediated GI symptoms and autism-like behavior in mouse offspring.
Wed Jun 01 00:00:00 EDT 2022
Nociceptive nerves regulate haematopoietic stem cell mobilization.
Nature
Gao X,Zhang D,Xu C,Li H,Caron KM,Frenette PS
Published figure using Ly-6A/E (Sca-1) monoclonal antibody (Product # 11-5981-82) in Flow Cytometry
Fri Jan 01 00:00:00 EST 2021
Photoreceptor protection by mesenchymal stem cell transplantation identifies exosomal MiR-21 as a therapeutic for retinal degeneration.
Cell death and differentiation
Deng CL,Hu CB,Ling ST,Zhao N,Bao LH,Zhou F,Xiong YC,Chen T,Sui BD,Yu XR,Hu CH
Published figure using Ly-6A/E (Sca-1) monoclonal antibody (Product # 11-5981-82) in Flow Cytometry
Mon Mar 01 00:00:00 EST 2021
Photoreceptor protection by mesenchymal stem cell transplantation identifies exosomal MiR-21 as a therapeutic for retinal degeneration.
Cell death and differentiation
Deng CL,Hu CB,Ling ST,Zhao N,Bao LH,Zhou F,Xiong YC,Chen T,Sui BD,Yu XR,Hu CH
Published figure using Ly-6A/E (Sca-1) monoclonal antibody (Product # 11-5981-82) in Flow Cytometry
Mon Mar 01 00:00:00 EST 2021
Loss of p53 in mesenchymal stem cells promotes alteration of bone remodeling through negative regulation of osteoprotegerin.
Cell death and differentiation
Velletri T,Huang Y,Wang Y,Li Q,Hu M,Xie N,Yang Q,Chen X,Chen Q,Shou P,Gan Y,Candi E,Annicchiarico-Petruzzelli M,Agostini M,Yang H,Melino G,Shi Y,Wang Y
Published figure using Ly-6A/E (Sca-1) monoclonal antibody (Product # 11-5981-82) in Flow Cytometry
Fri Jan 01 00:00:00 EST 2021
Chemotherapy triggers cachexia by deregulating synergetic function of histone-modifying enzymes.
Journal of cachexia, sarcopenia and muscle
Amrute-Nayak M,Pegoli G,Holler T,Lopez-Davila AJ,Lanzuolo C,Nayak A
11-5981 was used in Flow cytometry/Cell sorting to define a unique epigenetic mechanism targeted by distinct chemotherapeutic drugs, triggering chemotherapy-induced cachexia.
Mon Feb 01 00:00:00 EST 2021
RANKL from bone marrow adipose lineage cells promotes osteoclast formation and bone loss.
EMBO reports
Hu Y,Li X,Zhi X,Cong W,Huang B,Chen H,Wang Y,Li Y,Wang L,Fang C,Guo J,Liu Y,Cui J,Cao L,Weng W,Zhou Q,Wang S,Chen X,Su J
Published figure using Ly-6A/E (Sca-1) monoclonal antibody (Product # 11-5981-82) in Flow Cytometry
Mon Jul 05 00:00:00 EDT 2021
Tmem100- and Acta2-Lineage Cells Contribute to Implant Osseointegration in a Mouse Model.
Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research
Vesprey A,Suh ES,Göz Aytürk D,Yang X,Rogers M,Sosa B,Niu Y,Kalajzic I,Ivashkiv LB,Bostrom MP,Ayturk UM
11-5981-82 was used in Flow cytometry/Cell sorting to indicate that PαS cells are mobilized to repair bone tissue and participate in implant osseointegration after surgery.
Sat May 01 00:00:00 EDT 2021
Effects of signaling pathway inhibitors on hematopoietic stem cells.
Molecular medicine reports
Jiang Y,Xu Z,Ma N,Yin L,Hao C,Li J
Published figure using Ly-6A/E (Sca-1) monoclonal antibody (Product # 11-5981-82) in Flow Cytometry
Fri Jan 01 00:00:00 EST 2021
Age-related trabecular bone loss is associated with a decline in serum Galectin-1 level.
BMC musculoskeletal disorders
Xu W,Ni C,Wang Y,Zheng G,Zhang J,Xu Y
Published figure using Ly-6A/E (Sca-1) monoclonal antibody (Product # 11-5981-82) in Flow Cytometry
Tue Apr 27 00:00:00 EDT 2021
Age-related trabecular bone loss is associated with a decline in serum Galectin-1 level.
BMC musculoskeletal disorders
Xu W,Ni C,Wang Y,Zheng G,Zhang J,Xu Y
Published figure using Ly-6A/E (Sca-1) monoclonal antibody (Product # 11-5981-82) in Flow Cytometry
Tue Apr 27 00:00:00 EDT 2021
The IRE1/XBP1 signaling axis promotes skeletal muscle regeneration through a cell non-autonomous mechanism.
eLife
Roy A,Tomaz da Silva M,Bhat R,Bohnert KR,Iwawaki T,Kumar A
Published figure using Ly-6A/E (Sca-1) monoclonal antibody (Product # 11-5981-82) in Flow Cytometry
Tue Nov 23 00:00:00 EST 2021
Conditionally pathogenic genetic variants of a hematopoietic disease-suppressing enhancer.
Science advances
Soukup AA,Matson DR,Liu P,Johnson KD,Bresnick EH
Published figure using Ly-6A/E (Sca-1) monoclonal antibody (Product # 11-5981-82) in Flow Cytometry
Fri Dec 10 00:00:00 EST 2021
Therapeutic Potential of Mesenchymal Stem Cells in a Pre-Clinical Model of Diabetic Kidney Disease and Obesity.
International journal of molecular sciences
Sávio-Silva C,Soinski-Sousa PE,Simplício-Filho A,Bastos RMC,Beyerstedt S,Rangel ÉB
Published figure using Ly-6A/E (Sca-1) monoclonal antibody (Product # 11-5981-82) in Flow Cytometry
Thu Feb 04 00:00:00 EST 2021
Troy/Tnfrsf19 marks epidermal cells that govern interfollicular epidermal renewal and cornification.
Stem cell reports
Kretzschmar K,Boonekamp KE,Bleijs M,Asra P,Koomen M,Chuva de Sousa Lopes SM,Giovannone B,Clevers H
Published figure using Ly-6A/E (Sca-1) monoclonal antibody (Product # 11-5981-82) in Flow Cytometry
Tue Sep 14 00:00:00 EDT 2021
Activation of skeletal muscle-resident glial cells upon nerve injury.
JCI insight
Proietti D,Giordani L,De Bardi M,D'Ercole C,Lozanoska-Ochser B,Amadio S,Volonté C,Marinelli S,Muchir A,Bouché M,Borsellino G,Sacco A,Puri PL,Madaro L
Published figure using Ly-6A/E (Sca-1) monoclonal antibody (Product # 11-5981-82) in Flow Cytometry
Thu Apr 08 00:00:00 EDT 2021
Activation of skeletal muscle-resident glial cells upon nerve injury.
JCI insight
Proietti D,Giordani L,De Bardi M,D'Ercole C,Lozanoska-Ochser B,Amadio S,Volonté C,Marinelli S,Muchir A,Bouché M,Borsellino G,Sacco A,Puri PL,Madaro L
Published figure using Ly-6A/E (Sca-1) monoclonal antibody (Product # 11-5981-82) in Flow Cytometry
Thu Apr 08 00:00:00 EDT 2021
MAEA is an E3 ubiquitin ligase promoting autophagy and maintenance of haematopoietic stem cells.
Nature communications
Wei Q,Pinho S,Dong S,Pierce H,Li H,Nakahara F,Xu J,Xu C,Boulais PE,Zhang D,Maryanovich M,Cuervo AM,Frenette PS
Published figure using Ly-6A/E (Sca-1) monoclonal antibody (Product # 11-5981-82) in Flow Cytometry
Tue May 04 00:00:00 EDT 2021
Differential activation of Ca2+ influx channels modulate stem cell potency, their proliferation/viability and tissue regeneration.
NPJ Regenerative medicine
Ahamad N,Sun Y,Nascimento Da Conceicao V,Xavier Paul Ezhilan CRD,Natarajan M,Singh BB
Published figure using Ly-6A/E (Sca-1) monoclonal antibody (Product # 11-5981-82) in Immunohistochemistry
Wed Oct 20 00:00:00 EDT 2021
Wip1 regulates the immunomodulatory effects of murine mesenchymal stem cells in type 1 diabetes mellitus via targeting IFN-α/BST2.
Cell death discovery
Zhou N,Liu W,Zhang W,Liu Y,Li X,Wang Y,Zheng R,Zhang Y
11-5981-82 was used in Flow Cytometry to reveal Wip1 affects MSCs immunomodulation by regulating the expression of IFN-α/BST2.
Fri Oct 29 00:00:00 EDT 2021
Mechanism of exosomal miR-155 derived from bone marrow mesenchymal stem cells on stemness maintenance and drug resistance in myeloma cells.
Journal of orthopaedic surgery and research
Gao X,Zhou J,Wang J,Dong X,Chang Y,Jin Y
11-5981-82 was used in Flow Cytometry to explore the effect of exosomal miR-155 derived from bone marrow mesenchymal stem cells (BMSCs) on stemness maintenance and drug resistance in MPC-11 multiple myeloma cells.
Sun Oct 24 00:00:00 EDT 2021
Reticulon-1C Involvement in Muscle Regeneration.
Metabolites
Rossin F,Avitabile E,Catarinella G,Fornetti E,Testa S,Oliverio S,Gargioli C,Cannata S,Latella L,Di Sano F
11-5981-82 was used in Flow cytometry/Cell sorting to suggest that changes in muscle metabolism such as mitochondrial dysfunction and dysregulation of intracellular Ca2+ homeostasis are implicated in many adverse conditions affecting skeletal muscle.
Wed Dec 08 00:00:00 EST 2021
Marker-free lineage tracing reveals an environment-instructed clonogenic hierarchy in pancreatic cancer.
Cell reports
Lodestijn SC,Miedema DM,Lenos KJ,Nijman LE,Belt SC,El Makrini K,Lecca MC,Waasdorp C,van den Bosch T,Bijlsma MF,Vermeulen L
11-5981-82 was used in immunohistochemistry (frozen) to uncover pancreatic ductal adenocarcinoma tissue growth dynamics.
Tue Oct 19 00:00:00 EDT 2021
Targeting aberrant DNA methylation in mesenchymal stromal cells as a treatment for myeloma bone disease.
Nature communications
Garcia-Gomez A,Li T,de la Calle-Fabregat C,Rodríguez-Ubreva J,Ciudad L,Català-Moll F,Godoy-Tena G,Martín-Sánchez M,San-Segundo L,Muntión S,Morales X,Ortiz-de-Solórzano C,Oyarzabal J,San José-Enériz E,Esteller M,Agirre X,Prosper F,Garayoa M,Ballestar E
11-5981-82 was used in Flow Cytometry to study the efficacy of targeting methylation in myeloma bone disease.
Mon Jan 18 00:00:00 EST 2021
Microphthalmia transcription factor expression contributes to bone marrow failure in Fanconi anemia.
The Journal of clinical investigation
Oppezzo A,Bourseguin J,Renaud E,Pawlikowska P,Rosselli F
11-5981 was used in Flow cytometry/Cell sorting to the impact of the constitutive activation of stress signaling pathways on hematopoietic stem cell maintenance and function in Fanconi anemia.
Mon Mar 02 00:00:00 EST 2020
BCG vaccination-induced emergency granulopoiesis provides rapid protection from neonatal sepsis.
Science translational medicine
Brook B,Harbeson DJ,Shannon CP,Cai B,He D,Ben-Othman R,Francis F,Huang J,Varankovich N,Liu A,Bao W,Bjerregaard-Andersen M,Schaltz-Buchholzer F,Sanca L,Golding CN,Larsen KL,Levy O,Kampmann B,Tan R,Charles A,Wynn JL,Shann F,Aaby P,Benn CS,Tebbutt SJ,Kollmann TR,Amenyogbe N
11-5981 was used in Flow cytometry/Cell sorting to show that BCG was also protective in a mouse model of neonatal polymicrobial sepsis, where it induced granulocyte colony-stimulating factor (G-CSF) within hours of administration.
Wed May 06 00:00:00 EDT 2020
HDAC inhibitors tune miRNAs in extracellular vesicles of dystrophic muscle-resident mesenchymal cells.
EMBO reports
Sandonà M,Consalvi S,Tucciarone L,De Bardi M,Scimeca M,Angelini DF,Buffa V,D'Amico A,Bertini ES,Cazzaniga S,Bettica P,Bouché M,Bongiovanni A,Puri PL,Saccone V
11-5981-82 was used in Flow Cytometry to show that extracellular vesicles (EVs) released by mesenchymal cells (i.e., fibro-adipogenic progenitors-FAPs) mediate microRNA (miR) transfer to muscle stem cells (MuSCs) and that exposure of dystrophic FAPs to HDAC inhibitors (HDACis) increases the intra-EV levels of a subset of miRs, which cooperatively target biological processes of therapeutic interest, including regeneration, fibrosis, and inflammation.
Thu Sep 03 00:00:00 EDT 2020
Interleukin-11 regulates the fate of adipose-derived mesenchymal stem cells via STAT3 signalling pathways.
Cell proliferation
Yang W,Zhang S,Ou T,Jiang H,Jia D,Qi Z,Zou Y,Qian J,Sun A,Ge J
11-5981 was used in Flow cytometry/Cell sorting to determine whether IL-11 could improve therapeutic efficacy of adipose-derived mesenchymal stem cells (ADSCs) in ischaemic diseases.
Fri May 01 00:00:00 EDT 2020
Inflammatory Cytokines Alter Mesenchymal Stem Cell Mechanosensing and Adhesion on Stiffened Infarct Heart Tissue After Myocardial Infarction.
Frontiers in cell and developmental biology
Zhu D,Wu P,Xiao C,Hu W,Zhang T,Hu X,Chen W,Wang J
11-5981 was used in Flow cytometry/Cell sorting to provide new mechanistic insights of mechanical-inflammation coupling to improve MSC mechanosensing and adhesion.
Tue Nov 17 00:00:00 EST 2020
Multipotency of mouse trophoblast stem cells.
Stem cell research & therapy
Hou M,Han J,Li G,Kwon MY,Jiang J,Emani S,Taglauer ES,Park JA,Choi EB,Vodnala M,Fong YW,Emani SM,Rosas IO,Perrella MA,Liu X
Published figure using Ly-6A/E (Sca-1) monoclonal antibody (Product # 11-5981-82) in Immunocytochemistry
Thu Feb 13 00:00:00 EST 2020
Multipotency of mouse trophoblast stem cells.
Stem cell research & therapy
Hou M,Han J,Li G,Kwon MY,Jiang J,Emani S,Taglauer ES,Park JA,Choi EB,Vodnala M,Fong YW,Emani SM,Rosas IO,Perrella MA,Liu X
Published figure using Ly-6A/E (Sca-1) monoclonal antibody (Product # 11-5981-82) in Immunocytochemistry
Thu Feb 13 00:00:00 EST 2020
Multipotency of mouse trophoblast stem cells.
Stem cell research & therapy
Hou M,Han J,Li G,Kwon MY,Jiang J,Emani S,Taglauer ES,Park JA,Choi EB,Vodnala M,Fong YW,Emani SM,Rosas IO,Perrella MA,Liu X
Published figure using Ly-6A/E (Sca-1) monoclonal antibody (Product # 11-5981-82) in Immunocytochemistry
Thu Feb 13 00:00:00 EST 2020
Diamond Blackfan anemia is mediated by hyperactive Nemo-like kinase.
Nature communications
Wilkes MC,Siva K,Chen J,Varetti G,Youn MY,Chae H,Ek F,Olsson R,Lundbäck T,Dever DP,Nishimura T,Narla A,Glader B,Nakauchi H,Porteus MH,Repellin CE,Gazda HT,Lin S,Serrano M,Flygare J,Sakamoto KM
Published figure using Ly-6A/E (Sca-1) monoclonal antibody (Product # 11-5981-82) in Flow Cytometry
Fri Jul 03 00:00:00 EDT 2020
XIAOPI formula inhibits the pre-metastatic niche formation in breast cancer via suppressing TAMs/CXCL1 signaling.
Cell communication and signaling : CCS
Zheng Y,Wang N,Wang S,Yang B,Situ H,Zhong L,Lin Y,Wang Z
Published figure using Ly-6A/E (Sca-1) monoclonal antibody (Product # 11-5981-82) in Flow Cytometry
Thu Mar 26 00:00:00 EDT 2020
Use of Busulfan to Condition Mice for Bone Marrow Transplantation.
STAR protocols
Montecino-Rodriguez E,Dorshkind K
Published figure using Ly-6A/E (Sca-1) monoclonal antibody (Product # 11-5981-82) in Flow Cytometry
Fri Dec 18 00:00:00 EST 2020
Interaction of Deubiquitinase 2A-DUB/MYSM1 with DNA Repair and Replication Factors.
International journal of molecular sciences
Kroeger C,Roesler R,Wiese S,Hainzl A,Gatzka MV
Published figure using Ly-6A/E (Sca-1) monoclonal antibody (Product # 11-5981-82) in Flow Cytometry
Tue May 26 00:00:00 EDT 2020
A novel function of R-spondin1 in regulating estrogen receptor expression independent of Wnt/β-catenin signaling.
eLife
Geng A,Wu T,Cai C,Song W,Wang J,Yu QC,Zeng YA
Published figure using Ly-6A/E (Sca-1) monoclonal antibody (Product # 11-5981-82) in Flow Cytometry
Tue Aug 04 00:00:00 EDT 2020
Apoptotic bodies derived from mesenchymal stem cells promote cutaneous wound healing via regulating the functions of macrophages.
Stem cell research & therapy
Liu J,Qiu X,Lv Y,Zheng C,Dong Y,Dou G,Zhu B,Liu A,Wang W,Zhou J,Liu S,Liu S,Gao B,Jin Y
11-5981 was used in Flow cytometry/Cell sorting to demonstrate that transplanted MSCs promoted cutaneous wound healing partially through releasing apoptotic bodies which could convert the macrophages towards an anti-inflammatory phenotype that plays a crucial role in the tissue repair process.
Fri Nov 27 00:00:00 EST 2020
Apoptotic bodies derived from mesenchymal stem cells promote cutaneous wound healing via regulating the functions of macrophages.
Stem cell research & therapy
Liu J,Qiu X,Lv Y,Zheng C,Dong Y,Dou G,Zhu B,Liu A,Wang W,Zhou J,Liu S,Liu S,Gao B,Jin Y
11-5981 was used in Flow cytometry/Cell sorting to demonstrate that transplanted MSCs promoted cutaneous wound healing partially through releasing apoptotic bodies which could convert the macrophages towards an anti-inflammatory phenotype that plays a crucial role in the tissue repair process.
Fri Nov 27 00:00:00 EST 2020
Phosphatase SHP1 impedes mesenchymal stromal cell immunosuppressive capacity modulated by JAK1/STAT3 and P38 signals.
Cell & bioscience
Jiang M,Ye J,Wang X,Li N,Wang Y,Shi Y
Published figure using Ly-6A/E (Sca-1) monoclonal antibody (Product # 11-5981-82) in Flow Cytometry
Thu Apr 14 00:00:00 EDT 2022
Mesenchymal stem cells protect against malaria pathogenesis by reprogramming erythropoiesis in the bone marrow.
Cell death discovery
Thakur RS,Awasthi V,Sanyal A,Chatterjee S,Rani S,Chauhan R,Kalkal M,Tiwari M,Pande V,Das J
11-5981 was used in Flow cytometry/Cell sorting to suggest that MSCs play a critical role in host protection against malaria infection by modulating erythropoiesis and lymphopoiesis.
Sun Nov 15 00:00:00 EST 2020
Modest Declines in Proteome Quality Impair Hematopoietic Stem Cell Self-Renewal.
Cell reports
Hidalgo San Jose L,Sunshine MJ,Dillingham CH,Chua BA,Kruta M,Hong Y,Hatters DM,Signer RAJ
11-5981 was used in Flow cytometry/Cell sorting to show that hematopoietic stem cells (HSCs) are dependent on low protein synthesis to maintain proteostasis, which promotes their self-renewal.
Tue Jan 07 00:00:00 EST 2020
miR-142 induces accumulation of reactive oxygen species (ROS) by inhibiting pexophagy in aged bone marrow mesenchymal stem cells.
Scientific reports
Houri K,Mori T,Onodera Y,Tsujimoto T,Takehara T,Nakao S,Teramura T,Fukuda K
Published figure using Ly-6A/E (Sca-1) monoclonal antibody (Product # 11-5981-82) in Flow Cytometry
Fri Feb 28 00:00:00 EST 2020
Engineering a haematopoietic stem cell niche by revitalizing mesenchymal stromal cells.
Nature cell biology
Nakahara F,Borger DK,Wei Q,Pinho S,Maryanovich M,Zahalka AH,Suzuki M,Cruz CD,Wang Z,Xu C,Boulais PE,Ma'ayan A,Greally JM,Frenette PS
11-5981-82 was used in Flow Cytometry to provide insight into the transcriptional regulation of the niche with implications for stem cell-based therapies.
Wed May 01 00:00:00 EDT 2019
Long-term expansion and differentiation of adult murine epidermal stem cells in 3D organoid cultures.
Proceedings of the National Academy of Sciences of the United States of America
Boonekamp KE,Kretzschmar K,Wiener DJ,Asra P,Derakhshan S,Puschhof J,López-Iglesias C,Peters PJ,Basak O,Clevers H
Published figure using Ly-6A/E (Sca-1) monoclonal antibody (Product # 11-5981-82) in Flow Cytometry
Tue Jul 16 00:00:00 EDT 2019
Long-term expansion and differentiation of adult murine epidermal stem cells in 3D organoid cultures.
Proceedings of the National Academy of Sciences of the United States of America
Boonekamp KE,Kretzschmar K,Wiener DJ,Asra P,Derakhshan S,Puschhof J,López-Iglesias C,Peters PJ,Basak O,Clevers H
Published figure using Ly-6A/E (Sca-1) monoclonal antibody (Product # 11-5981-82) in Flow Cytometry
Tue Jul 16 00:00:00 EDT 2019
PDGFRA defines the mesenchymal stem cell Kaposi's sarcoma progenitors by enabling KSHV oncogenesis in an angiogenic environment.
PLoS pathogens
Naipauer J,Rosario S,Gupta S,Premer C,Méndez-Solís O,Schlesinger M,Ponzinibbio V,Jain V,Gay L,Renne R,Chan HL,Morey L,Salyakina D,Abba M,Williams S,Hare JM,Goldschmidt-Clermont PJ,Mesri EA
Published figure using Ly-6A/E (Sca-1) monoclonal antibody (Product # 11-5981-82) in Flow Cytometry
Sun Dec 01 00:00:00 EST 2019
Macrophages fine tune satellite cell fate in dystrophic skeletal muscle of mdx mice.
PLoS genetics
Madaro L,Torcinaro A,De Bardi M,Contino FF,Pelizzola M,Diaferia GR,Imeneo G,Bouchè M,Puri PL,De Santa F
Published figure using Ly-6A/E (Sca-1) monoclonal antibody (Product # 11-5981-82) in Flow Cytometry
Tue Oct 01 00:00:00 EDT 2019
TGFβ-induced degradation of TRAF3 in mesenchymal progenitor cells causes age-related osteoporosis.
Nature communications
Li J,Ayoub A,Xiu Y,Yin X,Sanders JO,Mesfin A,Xing L,Yao Z,Boyce BF
Published figure using Ly-6A/E (Sca-1) monoclonal antibody (Product # 11-5981-82) in Flow Cytometry
Wed Jun 26 00:00:00 EDT 2019
Excessive exosome release is the pathogenic pathway linking a lysosomal deficiency to generalized fibrosis.
Science advances
van de Vlekkert D,Demmers J,Nguyen XX,Campos Y,Machado E,Annunziata I,Hu H,Gomero E,Qiu X,Bongiovanni A,Feghali-Bostwick CA,d'Azzo A
Published figure using Ly-6A/E (Sca-1) monoclonal antibody (Product # 11-5981-82) in Flow Cytometry
Mon Jul 01 00:00:00 EDT 2019
The microRNAs miR-204 and miR-211 maintain joint homeostasis and protect against osteoarthritis progression.
Nature communications
Huang J,Zhao L,Fan Y,Liao L,Ma PX,Xiao G,Chen D
Published figure using Ly-6A/E (Sca-1) monoclonal antibody (Product # 11-5981-82) in Flow Cytometry
Fri Jun 28 00:00:00 EDT 2019
Procr-expressing progenitor cells are responsible for murine ovulatory rupture repair of ovarian surface epithelium.
Nature communications
Wang J,Wang D,Chu K,Li W,Zeng YA
Published figure using Ly-6A/E (Sca-1) monoclonal antibody (Product # 11-5981-82) in Flow Cytometry
Thu Oct 31 00:00:00 EDT 2019
Breast Tumor Cells Highly Resistant to Drugs Are Controlled Only by the Immune Response Induced in an Immunocompetent Mouse Model.
Integrative cancer therapies
Lasso P,Llano Murcia M,Sandoval TA,Urueña C,Barreto A,Fiorentino S
Published figure using Ly-6A/E (Sca-1) monoclonal antibody (Product # 11-5981-82) in Flow Cytometry
Wed Dec 11 00:00:00 EST 2019
Quiescent Tissue Stem Cells Evade Immune Surveillance.
Immunity
Agudo J,Park ES,Rose SA,Alibo E,Sweeney R,Dhainaut M,Kobayashi KS,Sachidanandam R,Baccarini A,Merad M,Brown BD
11-5981 was used in Flow cytometry/Cell sorting to identify a link between stem cell quiescence, antigen presentation, and immune evasion.
Tue Feb 20 00:00:00 EST 2018
A Circular RNA Protects Dormant Hematopoietic Stem Cells from DNA Sensor cGAS-Mediated Exhaustion.
Immunity
Xia P,Wang S,Ye B,Du Y,Li C,Xiong Z,Qu Y,Fan Z
11-5981 was used in Flow cytometry/Cell sorting to study circular RNA-mediated maintenance of hematopoeitic stem cell homeostasis.
Tue Apr 17 00:00:00 EDT 2018
Lack of Cardiac Improvement After Cardiosphere-Derived Cell Transplantation in Aging Mouse Hearts.
Circulation research
Zhao ZA,Han X,Lei W,Li J,Yang Z,Wu J,Yao M,Lu XA,He L,Chen Y,Zhou B,Hu S
11-5981 was used in Flow cytometry/Cell sorting to evaluate the effect of cardiosphere-derived cell injection on an ageing heart.
Fri Oct 26 00:00:00 EDT 2018
PDGF is a potent initiator of bone formation in a tissue engineered model of pathological ossification.
Journal of tissue engineering and regenerative medicine
Davies OG,Grover LM,Lewis MP,Liu Y
Published figure using Ly-6A/E (Sca-1) monoclonal antibody (Product # 11-5981-82) in Flow Cytometry
Mon Jan 01 00:00:00 EST 2018
Simultaneous isolation of mesenchymal stem cells and endothelial progenitor cells derived from murine bone marrow.
Experimental and therapeutic medicine
Wang X,Zhao Z,Zhang H,Hou J,Feng W,Zhang M,Guo J,Xia J,Ge Q,Chen X,Wu X
Published figure using Ly-6A/E (Sca-1) monoclonal antibody (Product # 11-5981-82) in Flow Cytometry
Sat Dec 01 00:00:00 EST 2018
The H3K4 methyltransferase Setd1b is essential for hematopoietic stem and progenitor cell homeostasis in mice.
eLife
Schmidt K,Zhang Q,Tasdogan A,Petzold A,Dahl A,Arneth BM,Slany R,Fehling HJ,Kranz A,Stewart AF,Anastassiadis K
Published figure using Ly-6A/E (Sca-1) monoclonal antibody (Product # 11-5981-82) in Flow Cytometry
Tue Jun 19 00:00:00 EDT 2018
Tracking of Adipose-Derived Mesenchymal Stromal/Stem Cells in a Model of Cisplatin-Induced Acute Kidney Injury: Comparison of Bioluminescence Imaging versus qRT-PCR.
International journal of molecular sciences
Schubert R,Sann J,Frueh JT,Ullrich E,Geiger H,Baer PC
Published figure using Ly-6A/E (Sca-1) monoclonal antibody (Product # 11-5981-82) in Flow Cytometry
Wed Aug 29 00:00:00 EDT 2018
Differential requirement of kindlin-3 for T cell progenitor homing to the non-vascularized and vascularized thymus.
eLife
Moretti FA,Klapproth S,Ruppert R,Margraf A,Weber J,Pick R,Scheiermann C,Sperandio M,Fässler R,Moser M
Published figure using Ly-6A/E (Sca-1) monoclonal antibody (Product # 11-5981-82) in Flow Cytometry
Thu Sep 06 00:00:00 EDT 2018
HMGB2 is a novel adipogenic factor that regulates ectopic fat infiltration in skeletal muscles.
Scientific reports
Lee D,Taniguchi N,Sato K,Choijookhuu N,Hishikawa Y,Kataoka H,Morinaga H,Lotz M,Chosa E
Published figure using Ly-6A/E (Sca-1) monoclonal antibody (Product # 11-5981-82) in Flow Cytometry
Mon Jun 25 00:00:00 EDT 2018
HMGB2 is a novel adipogenic factor that regulates ectopic fat infiltration in skeletal muscles.
Scientific reports
Lee D,Taniguchi N,Sato K,Choijookhuu N,Hishikawa Y,Kataoka H,Morinaga H,Lotz M,Chosa E
Published figure using Ly-6A/E (Sca-1) monoclonal antibody (Product # 11-5981-82) in Flow Cytometry
Mon Jun 25 00:00:00 EDT 2018
Stem cell factor is selectively secreted by arterial endothelial cells in bone marrow.
Nature communications
Xu C,Gao X,Wei Q,Nakahara F,Zimmerman SE,Mar J,Frenette PS
Published figure using Ly-6A/E (Sca-1) monoclonal antibody (Product # 11-5981-82) in Flow Cytometry
Fri Jun 22 00:00:00 EDT 2018
Stem cell factor is selectively secreted by arterial endothelial cells in bone marrow.
Nature communications
Xu C,Gao X,Wei Q,Nakahara F,Zimmerman SE,Mar J,Frenette PS
Published figure using Ly-6A/E (Sca-1) monoclonal antibody (Product # 11-5981-82) in Flow Cytometry
Fri Jun 22 00:00:00 EDT 2018
RhoA, Rac1, and Cdc42 differentially regulate αSMA and collagen I expression in mesenchymal stem cells.
The Journal of biological chemistry
Ge J,Burnier L,Adamopoulou M,Kwa MQ,Schaks M,Rottner K,Brakebusch C
Published figure using Ly-6A/E (Sca-1) monoclonal antibody (Product # 11-5981-82) in Flow Cytometry
Fri Jun 15 00:00:00 EDT 2018
MERTK inhibition alters the PD-1 axis and promotes anti-leukemia immunity.
JCI insight
Lee-Sherick AB,Jacobsen KM,Henry CJ,Huey MG,Parker RE,Page LS,Hill AA,Wang X,Frye SV,Earp HS,Jordan CT,DeRyckere D,Graham DK
11-5981 was used in Flow cytometry/Cell sorting to demonstrate both the direct therapeutic effects of MERTK inhibition on leukaemia cells and the induction of anti-leukaemia immunity via suppression of the coinhibitory PD-1 axis.
Fri Nov 02 00:00:00 EDT 2018
Diabetes impairs wound healing by Dnmt1-dependent dysregulation of hematopoietic stem cells differentiation towards macrophages.
Nature communications
Yan J,Tie G,Wang S,Tutto A,DeMarco N,Khair L,Fazzio TG,Messina LM
11-5981 was used in Flow cytometry/Cell sorting to demonstrate for the first time that type 2 diabetes mellitus induces an haematopoietic stem cell-autonomous mechanism that causes impaired wound healing.
Tue Jan 02 00:00:00 EST 2018
Bone marrow-derived immature myeloid cells are a main source of circulating suPAR contributing to proteinuric kidney disease.
Nature medicine
Hahm E,Wei C,Fernandez I,Li J,Tardi NJ,Tracy M,Wadhwani S,Cao Y,Peev V,Zloza A,Lusciks J,Hayek SS,O'Connor C,Bitzer M,Gupta V,Sever S,Sykes DB,Scadden DT,Reiser J
Sun Jan 01 00:00:00 EST 2017
Bone marrow-derived immature myeloid cells are a main source of circulating suPAR contributing to proteinuric kidney disease.
Nature medicine
Hahm E,Wei C,Fernandez I,Li J,Tardi NJ,Tracy M,Wadhwani S,Cao Y,Peev V,Zloza A,Lusciks J,Hayek SS,O'Connor C,Bitzer M,Gupta V,Sever S,Sykes DB,Scadden DT,Reiser J
Sun Jan 01 00:00:00 EST 2017
Differential cytokine contributions of perivascular haematopoietic stem cell niches.
Nature cell biology
Asada N,Kunisaki Y,Pierce H,Wang Z,Fernandez NF,Birbrair A,Ma'ayan A,Frenette PS
11-5981 was used in Flow cytometry/Cell sorting to demonstrate that the effects of cytokines regulating haematopoietic stem cell functions are dependent on the producing cell sources.
Wed Mar 01 00:00:00 EST 2017
FOXP1 controls mesenchymal stem cell commitment and senescence during skeletal aging.
The Journal of clinical investigation
Li H,Liu P,Xu S,Li Y,Dekker JD,Li B,Fan Y,Zhang Z,Hong Y,Yang G,Tang T,Ren Y,Tucker HO,Yao Z,Guo X
Published figure using Ly-6A/E (Sca-1) monoclonal antibody (Product # 11-5981-82) in Flow Cytometry
Mon Apr 03 00:00:00 EDT 2017
GATA4-dependent organ-specific endothelial differentiation controls liver development and embryonic hematopoiesis.
The Journal of clinical investigation
Géraud C,Koch PS,Zierow J,Klapproth K,Busch K,Olsavszky V,Leibing T,Demory A,Ulbrich F,Diett M,Singh S,Sticht C,Breitkopf-Heinlein K,Richter K,Karppinen SM,Pihlajaniemi T,Arnold B,Rodewald HR,Augustin HG,Schledzewski K,Goerdt S
Published figure using Ly-6A/E (Sca-1) monoclonal antibody (Product # 11-5981-82) in Flow Cytometry
Wed Mar 01 00:00:00 EST 2017
miR-155 induces ROS generation through downregulation of antioxidation-related genes in mesenchymal stem cells.
Aging cell
Onodera Y,Teramura T,Takehara T,Obora K,Mori T,Fukuda K
11-5981 was used in Flow cytometry/Cell sorting to identify miR-155 as an inducer of reactive oxygen species generation in mesenchymal stem cells.
Fri Dec 01 00:00:00 EST 2017
Acarbose Accelerates Wound Healing via Akt/eNOS Signaling in db/db Mice.
Oxidative medicine and cellular longevity
Han X,Deng Y,Yu J,Sun Y,Ren G,Cai J,Zhu J,Jiang G
11-5981 was used in Flow cytometry/Cell sorting to suggest a potential effect of acarbose in promoting wound healing and improving angiogenesis in T2DM mice.
Wed Jun 21 00:00:00 EDT 2017
Resveratrol activates endogenous cardiac stem cells and improves myocardial regeneration following acute myocardial infarction.
Molecular medicine reports
Ling L,Gu S,Cheng Y
11-5981 was used in Immunofluorescence to investigate how resveratrol affects cardiac stem cells (CSCs), and optimize CSCs therapy for myocardial regeneration post-acute myocardial infarction.
Wed Mar 01 00:00:00 EST 2017
Induced p53 loss in mouse luminal cells causes clonal expansion and development of mammary tumours.
Nature communications
Tao L,Xiang D,Xie Y,Bronson RT,Li Z
Published figure using Ly-6A/E (Sca-1) monoclonal antibody (Product # 11-5981-82) in Flow Cytometry
Mon Feb 13 00:00:00 EST 2017
Mutant U2AF1-expressing cells are sensitive to pharmacological modulation of the spliceosome.
Nature communications
Shirai CL,White BS,Tripathi M,Tapia R,Ley JN,Ndonwi M,Kim S,Shao J,Carver A,Saez B,Fulton RS,Fronick C,O'Laughlin M,Lagisetti C,Webb TR,Graubert TA,Walter MJ
Published figure using Ly-6A/E (Sca-1) monoclonal antibody (Product # 11-5981-82) in Flow Cytometry
Mon Jan 09 00:00:00 EST 2017
Microgrooved-surface topography enhances cellular division and proliferation of mouse bone marrow-derived mesenchymal stem cells.
PloS one
Chaudhary JK,Rath PC
Thu Oct 19 00:00:00 EDT 2017
Zoledronate suppressed angiogenesis and osteogenesis by inhibiting osteoclasts formation and secretion of PDGF-BB.
PloS one
Gao SY,Zheng GS,Wang L,Liang YJ,Zhang SE,Lao XM,Li K,Liao GQ
Published figure using Ly-6A/E (Sca-1) monoclonal antibody (Product # 11-5981-82) in Flow Cytometry
Mon Sep 18 00:00:00 EDT 2017
Praja1 E3 ubiquitin ligase promotes skeletal myogenesis through degradation of EZH2 upon p38α activation.
Nature communications
Consalvi S,Brancaccio A,Dall'Agnese A,Puri PL,Palacios D
11-5981 was used in Flow cytometry/Cell sorting to determine that signal-dependent degradation of EZH2, a PRC2 subunit, is a prerequisite for satellite cell differentiation.
Mon Jan 09 00:00:00 EST 2017
Longitudinal intravital imaging of the femoral bone marrow reveals plasticity within marrow vasculature.
Nature communications
Reismann D,Stefanowski J,Günther R,Rakhymzhan A,Matthys R,Nützi R,Zehentmeier S,Schmidt-Bleek K,Petkau G,Chang HD,Naundorf S,Winter Y,Melchers F,Duda G,Hauser AE,Niesner RA
Published figure using Ly-6A/E (Sca-1) monoclonal antibody (Product # 11-5981-82) in Immunofluorescence
Mon Dec 18 00:00:00 EST 2017
The Deubiquitinase OTULIN Is an Essential Negative Regulator of Inflammation and Autoimmunity.
Cell
Damgaard RB,Walker JA,Marco-Casanova P,Morgan NV,Titheradge HL,Elliott PR,McHale D,Maher ER,McKenzie ANJ,Komander D
Published figure using Ly-6A/E (Sca-1) monoclonal antibody (Product # 11-5981-82) in Flow Cytometry
Thu Aug 25 00:00:00 EDT 2016
Core Circadian Clock Genes Regulate Leukemia Stem Cells in AML.
Cell
Puram RV,Kowalczyk MS,de Boer CG,Schneider RK,Miller PG,McConkey M,Tothova Z,Tejero H,Heckl D,Järås M,Chen MC,Li H,Tamayo A,Cowley GS,Rozenblatt-Rosen O,Al-Shahrour F,Regev A,Ebert BL
11-5981 was used in Flow cytometry/Cell sorting to identify essential transcription factors in a murine model of acute myeloid leukemia with genetically and phenotypically defined leukaemia stem cells.
Thu Apr 07 00:00:00 EDT 2016
Mesenchymal stromal cell-derived extracellular vesicles rescue radiation damage to murine marrow hematopoietic cells.
Leukemia
Wen S,Dooner M,Cheng Y,Papa E,Del Tatto M,Pereira M,Deng Y,Goldberg L,Aliotta J,Chatterjee D,Stewart C,Carpanetto A,Collino F,Bruno S,Camussi G,Quesenberry P
11-5981 was used in Flow cytometry/Cell sorting to evaluate the capacity of mesenchymal stromal cell-derived extracellular vesicles to rescue murine marrow hematopoietic cells damage following exposure to radiation, showing that damage could be reversed using both murine and human MSC-EVs.
Tue Nov 01 00:00:00 EDT 2016
Hedgehog-driven myogenic tumors recapitulate skeletal muscle cellular heterogeneity.
Experimental cell research
Hettmer S,Lin MM,Tchessalova D,Tortorici SJ,Castiglioni A,Desai T,Mao J,McMahon AP,Wagers AJ
Published figure using Ly-6A/E (Sca-1) monoclonal antibody (Product # 11-5981-82) in Flow Cytometry
Fri Jan 01 00:00:00 EST 2016
Identification of an epidermal keratinocyte AMPA glutamate receptor involved in dermatopathies associated with sensory abnormalities.
Pain reports
Cabañero D,Irie T,Celorrio M,Trousdale C,Owens DM,Virley D,Albrecht PJ,Caterina MJ,Rice FL,Morón JA
Published figure using Ly-6A/E (Sca-1) monoclonal antibody (Product # 11-5981-82) in Flow Cytometry
Thu Sep 01 00:00:00 EDT 2016
Laminin regulates PDGFRβ(+) cell stemness and muscle development.
Nature communications
Yao Y,Norris EH,Mason CE,Strickland S
11-5981 was used in Flow cytometry/Cell sorting to show that laminin has a critical role in the control of PDGFRBeta(+) cell stemness and that PDGFRBeta(+) may be a drug target for treatment of muscular dystrophy.
Tue May 03 00:00:00 EDT 2016
MHC-compatible bone marrow stromal/stem cells trigger fibrosis by activating host T cells in a scleroderma mouse model.
eLife
Ogawa Y,Morikawa S,Okano H,Mabuchi Y,Suzuki S,Yaguchi T,Sato Y,Mukai S,Yaguchi S,Inaba T,Okamoto S,Kawakami Y,Tsubota K,Matsuzaki Y,Shimmura S
11-5981 was used in Flow cytometry/Cell sorting to investigate the fibrosis in a scleroderma mouse model which is triggered by antigen mismatched bone marrow stromal/stem cells.
Tue Jan 26 00:00:00 EST 2016
Identification of a CD133-CD55- population functions as a fetal common skeletal progenitor.
Scientific reports
Weng L,Hu X,Kumar B,Garcia M,Todorov I,Jung X,Marcucci G,Forman SJ,Chen CC
Published figure using Ly-6A/E (Sca-1) monoclonal antibody (Product # 11-5981-82) in Immunofluorescence
Thu Dec 08 00:00:00 EST 2016
Reprogramming mouse fibroblasts into engraftable myeloerythroid and lymphoid progenitors.
Nature communications
Cheng H,Ang HY,A El Farran C,Li P,Fang HT,Liu TM,Kong SL,Chin ML,Ling WY,Lim EK,Li H,Huber T,Loh KM,Loh YH,Lim B
11-5981 was used in Flow cytometry/Cell sorting to demonstrate how it is possible to reprogram mouse embryonic fibroblasts into engraftable blood progenitors.
Mon Nov 21 00:00:00 EST 2016
KLF4-dependent phenotypic modulation of smooth muscle cells has a key role in atherosclerotic plaque pathogenesis.
Nature medicine
Shankman LS,Gomez D,Cherepanova OA,Salmon M,Alencar GF,Haskins RM,Swiatlowska P,Newman AA,Greene ES,Straub AC,Isakson B,Randolph GJ,Owens GK
Published figure using Ly-6A/E (Sca-1) monoclonal antibody (Product # 11-5981-82) in Immunofluorescence
Mon Jun 01 00:00:00 EDT 2015
KLF4-dependent phenotypic modulation of smooth muscle cells has a key role in atherosclerotic plaque pathogenesis.
Nature medicine
Shankman LS,Gomez D,Cherepanova OA,Salmon M,Alencar GF,Haskins RM,Swiatlowska P,Newman AA,Greene ES,Straub AC,Isakson B,Randolph GJ,Owens GK
Published figure using Ly-6A/E (Sca-1) monoclonal antibody (Product # 11-5981-82) in Immunofluorescence
Mon Jun 01 00:00:00 EDT 2015
Rapid depot-specific activation of adipocyte precursor cells at the onset of obesity.
Nature cell biology
Jeffery E,Church CD,Holtrup B,Colman L,Rodeheffer MS
Published figure using Ly-6A/E (Sca-1) monoclonal antibody (Product # 11-5981-82) in Flow Cytometry
Wed Apr 01 00:00:00 EDT 2015
Rapid depot-specific activation of adipocyte precursor cells at the onset of obesity.
Nature cell biology
Jeffery E,Church CD,Holtrup B,Colman L,Rodeheffer MS
Published figure using Ly-6A/E (Sca-1) monoclonal antibody (Product # 11-5981-82) in Flow Cytometry
Wed Apr 01 00:00:00 EDT 2015
Cis-regulatory mechanisms governing stem and progenitor cell transitions.
Science advances
Johnson KD,Kong G,Gao X,Chang YI,Hewitt KJ,Sanalkumar R,Prathibha R,Ranheim EA,Dewey CN,Zhang J,Bresnick EH
Published figure using Ly-6A/E (Sca-1) monoclonal antibody (Product # 11-5981-82) in Flow Cytometry
Tue Sep 01 00:00:00 EDT 2015
Brahma is required for cell cycle arrest and late muscle gene expression during skeletal myogenesis.
EMBO reports
Albini S,Coutinho Toto P,Dall'Agnese A,Malecova B,Cenciarelli C,Felsani A,Caruso M,Bultman SJ,Puri PL
11-5981 was used in Flow cytometry/Cell sorting to show that Brahma and Brg1 have distinct functions at discrete stages of muscle differentiation.
Sat Aug 01 00:00:00 EDT 2015
Pretreatment of Mesenchymal Stem Cells Manipulates Their Vasculoprotective Potential While Not Altering Their Homing Within the Injured Gut.
Stem cells (Dayton, Ohio)
Kavanagh DP,Suresh S,Newsome PN,Frampton J,Kalia N
11-5981 was used in Flow cytometry/Cell sorting to demonstrate that MSCs can limit leukocyte recruitment and improve tissue perfusion following intestinal ischemia-reperfusion injury.
Tue Sep 01 00:00:00 EDT 2015
Cellular and molecular characterization of human cardiac stem cells reveals key features essential for their function and safety.
Stem cells and development
Vahdat S,Mousavi SA,Omrani G,Gholampour M,Sotoodehnejadnematalahi F,Ghazizadeh Z,Gharechahi J,Baharvand H,Salekdeh GH,Aghdami N
Published figure using Ly-6A/E (Sca-1) monoclonal antibody (Product # 11-5981-82) in Flow Cytometry
Mon Jun 15 00:00:00 EDT 2015
Multi-Drug Resistance ABC Transporter Inhibition Enhances Murine Ventral Prostate Stem/Progenitor Cell Differentiation.
Stem cells and development
Samant MD,Jackson CM,Felix CL,Jones AJ,Goodrich DW,Foster BA,Huss WJ
Published figure using Ly-6A/E (Sca-1) monoclonal antibody (Product # 11-5981-82) in Flow Cytometry
Fri May 15 00:00:00 EDT 2015
Limited miR-17-92 overexpression drives hematologic malignancies.
Leukemia research
Danielson LS,Reavie L,Coussens M,Davalos V,Castillo-Martin M,Guijarro MV,Coffre M,Cordon-Cardo C,Aifantis I,Ibrahim S,Liu C,Koralov SB,Hernando E
Published figure using Ly-6A/E (Sca-1) monoclonal antibody (Product # 11-5981-82) in Flow Cytometry
Sun Mar 01 00:00:00 EST 2015
Role of T-cell reconstitution in HIV-1 antiretroviral therapy-induced bone loss.
Nature communications
Ofotokun I,Titanji K,Vikulina T,Roser-Page S,Yamaguchi M,Zayzafoon M,Williams IR,Weitzmann MN
11-5981 was used in Flow cytometry/Cell sorting to suggest T-cell repopulation and/or immune reconstitution as putative mechanisms for bone loss following ART initiation.
Tue Sep 22 00:00:00 EDT 2015
Cardiac-Specific Activation of IKK2 Leads to Defects in Heart Development and Embryonic Lethality.
PloS one
Kraut B,Maier HJ,Kókai E,Fiedler K,Boettger T,Illing A,Kostin S,Walther P,Braun T,Wirth T
Published figure using Ly-6A/E (Sca-1) monoclonal antibody (Product # 11-5981-82) in Immunofluorescence
Mon Jun 13 00:00:00 EDT 2016
Rivaroxaban, a factor Xa inhibitor, improves neovascularization in the ischemic hindlimb of streptozotocin-induced diabetic mice.
Cardiovascular diabetology
Wu TC,Chan JS,Lee CY,Leu HB,Huang PH,Chen JS,Lin SJ,Chen JW
11-5981 was used in Flow cytometry/Cell sorting to demonstrate that rivaroxaban promotes vessel formation in diabetic mice and improves endothelial progenitor cell function under hyperglycemic conditions.
Tue Jun 16 00:00:00 EDT 2015
Megakaryocytes regulate hematopoietic stem cell quiescence through CXCL4 secretion.
Nature medicine
Bruns I,Lucas D,Pinho S,Ahmed J,Lambert MP,Kunisaki Y,Scheiermann C,Schiff L,Poncz M,Bergman A,Frenette PS
11-5981 was used in Flow cytometry/Cell sorting to indicate that a terminally differentiated cell type derived from HSCs contributes to the HSC niche, directly regulating HSC behavior.
Sat Nov 01 00:00:00 EDT 2014
The miR-126-VEGFR2 axis controls the innate response to pathogen-associated nucleic acids.
Nature immunology
Agudo J,Ruzo A,Tung N,Salmon H,Leboeuf M,Hashimoto D,Becker C,Garrett-Sinha LA,Baccarini A,Merad M,Brown BD
11-5981 was used in Flow cytometry/Cell sorting to identify the miR-126-VEGFR2 axis as an important regulator of the innate response that operates through multiscale control of pDCs.
Wed Jan 01 00:00:00 EST 2014
Cardiogenic genes expressed in cardiac fibroblasts contribute to heart development and repair.
Circulation research
Furtado MB,Costa MW,Pranoto EA,Salimova E,Pinto AR,Lam NT,Park A,Snider P,Chandran A,Harvey RP,Boyd R,Conway SJ,Pearson J,Kaye DM,Rosenthal NA
Published figure using Ly-6A/E (Sca-1) monoclonal antibody (Product # 11-5981-82) in Flow Cytometry
Fri Apr 25 00:00:00 EDT 2014
WASH is required for the differentiation commitment of hematopoietic stem cells in a c-Myc-dependent manner.
The Journal of experimental medicine
Xia P,Wang S,Huang G,Zhu P,Li M,Ye B,Du Y,Fan Z
Published figure using Ly-6A/E (Sca-1) monoclonal antibody (Product # 11-5981-82) in Flow Cytometry
Mon Sep 22 00:00:00 EDT 2014
Overexpressing sonic hedgehog peptide restores periosteal bone formation in a murine bone allograft transplantation model.
Molecular therapy : the journal of the American Society of Gene Therapy
Huang C,Tang M,Yehling E,Zhang X
Published figure using Ly-6A/E (Sca-1) monoclonal antibody (Product # 11-5981-82) in Flow Cytometry
Sat Feb 01 00:00:00 EST 2014
The Notch1 transcriptional activation domain is required for development and reveals a novel role for Notch1 signaling in fetal hematopoietic stem cells.
Genes & development
Gerhardt DM,Pajcini KV,D'altri T,Tu L,Jain R,Xu L,Chen MJ,Rentschler S,Shestova O,Wertheim GB,Tobias JW,Kluk M,Wood AW,Aster JC,Gimotty PA,Epstein JA,Speck N,Bigas A,Pear WS
11-5981 was used in Flow cytometry/Cell sorting to describe additional functions for Notch1 in embryonic haematopoietic stem cell biology.
Sat Mar 15 00:00:00 EDT 2014
Epidermal Wnt/β-catenin signaling regulates adipocyte differentiation via secretion of adipogenic factors.
Proceedings of the National Academy of Sciences of the United States of America
Donati G,Proserpio V,Lichtenberger BM,Natsuga K,Sinclair R,Fujiwara H,Watt FM
11-5981 was used in Flow cytometry/Cell sorting to elucidate the mechanisms by which the epidermis can regulate adipogenesis.
Tue Apr 15 00:00:00 EDT 2014
Epidermal Wnt/β-catenin signaling regulates adipocyte differentiation via secretion of adipogenic factors.
Proceedings of the National Academy of Sciences of the United States of America
Donati G,Proserpio V,Lichtenberger BM,Natsuga K,Sinclair R,Fujiwara H,Watt FM
11-5981 was used in Flow cytometry/Cell sorting to elucidate the mechanisms by which the epidermis can regulate adipogenesis.
Tue Apr 15 00:00:00 EDT 2014
Cell-autonomous heparanase modulates self-renewal and migration in bone marrow-derived mesenchymal stem cells.
Journal of biomedical science
Cheng CC,Lee YH,Lin SP,Huangfu WC,Liu IH
Published figure using Ly-6A/E (Sca-1) monoclonal antibody (Product # 11-5981-82) in Flow Cytometry
Thu Mar 13 00:00:00 EDT 2014
Smurf2 regulates hematopoietic stem cell self-renewal and aging.
Aging cell
Ramkumar C,Kong Y,Trabucco SE,Gerstein RM,Zhang H
11-5981 was used in Flow cytometry/Cell sorting to suggest that Smurf2 plays an important role in regulating HSC self-renewal and ageing.
Sun Jun 01 00:00:00 EDT 2014
Immunogenicity of undifferentiated and differentiated allogeneic mouse mesenchymal stem cells.
Journal of tissue engineering
Mukonoweshuro B,Brown CJ,Fisher J,Ingham E
11-5981 was used in Flow cytometry/Cell sorting to determine that although mesenchymal stem cells possess immunosuppressive properties, they may not be immunoprivileged.
Fri May 09 00:00:00 EDT 2014
Recruitment of bone marrow-derived cells to periodontal tissue defects.
Frontiers in cell and developmental biology
Kimura Y,Komaki M,Iwasaki K,Sata M,Izumi Y,Morita I
Published figure using Ly-6A/E (Sca-1) monoclonal antibody (Product # 11-5981-82) in Flow Cytometry
Mon Nov 03 00:00:00 EST 2014
Sca1⁺ murine pituitary adenoma cells show tumor-growth advantage.
Endocrine-related cancer
Donangelo I,Ren SG,Eigler T,Svendsen C,Melmed S
11-5981 was used in Flow cytometry/Cell sorting to show that Sca1(+) cells derived from benign pituitary tumors exhibit an undifferentiated expression profile and tumor-proliferative advantages.
Tue Apr 01 00:00:00 EDT 2014
Sca1⁺ murine pituitary adenoma cells show tumor-growth advantage.
Endocrine-related cancer
Donangelo I,Ren SG,Eigler T,Svendsen C,Melmed S
11-5981 was used in Flow cytometry/Cell sorting to show that Sca1(+) cells derived from benign pituitary tumors exhibit an undifferentiated expression profile and tumor-proliferative advantages.
Tue Apr 01 00:00:00 EDT 2014
Sca1⁺ murine pituitary adenoma cells show tumor-growth advantage.
Endocrine-related cancer
Donangelo I,Ren SG,Eigler T,Svendsen C,Melmed S
11-5981 was used in Flow cytometry/Cell sorting to show that Sca1(+) cells derived from benign pituitary tumors exhibit an undifferentiated expression profile and tumor-proliferative advantages.
Tue Apr 01 00:00:00 EDT 2014
IFN-γ-producing and IL-17-producing γδ T cells differentiate at distinct developmental stages in murine fetal thymus.
Journal of immunology (Baltimore, Md. : 1950)
Shibata K,Yamada H,Nakamura M,Hatano S,Katsuragi Y,Kominami R,Yoshikai Y
11-5981 was used in Flow cytometry/Cell sorting to compare the functions of γδ T cells derived from double-negative 2 and double-negative 3 cells in the murine fetal thymus.
Sat Mar 01 00:00:00 EST 2014
Central role of conventional dendritic cells in regulation of bone marrow release and survival of neutrophils.
Journal of immunology (Baltimore, Md. : 1950)
Jiao J,Dragomir AC,Kocabayoglu P,Rahman AH,Chow A,Hashimoto D,Leboeuf M,Kraus T,Moran T,Carrasco-Avino G,Friedman SL,Merad M,Aloman C
11-5981 was used in Flow cytometry/Cell sorting to investigate the role of dendritic cells in neutrophil homeostasis, showing a central role in regulation of bone marrow release and survival of neutrophils.
Tue Apr 01 00:00:00 EDT 2014
Evidence for Transfer of Membranes from Mesenchymal Stem Cells to HL-1 Cardiac Cells.
Stem cells international
Boomsma RA,Geenen DL
Published figure using Ly-6A/E (Sca-1) monoclonal antibody (Product # 11-5981-82) in Flow Cytometry
Wed Oct 08 00:00:00 EDT 2014
Immunohistological localization of endogenous unlabeled stem cells in wounded skin.
The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society
Hong S,Alapure BV,Lu Y,Tian H,Wang Q
Published figure using Ly-6A/E (Sca-1) monoclonal antibody (Product # 11-5981-82) in Immunofluorescence
Tue Apr 01 00:00:00 EDT 2014
Amniotic fluid stem cells prevent follicle atresia and rescue fertility of mice with premature ovarian failure induced by chemotherapy.
PloS one
Xiao GY,Liu IH,Cheng CC,Chang CC,Lee YH,Cheng WT,Wu SC
Published figure using Ly-6A/E (Sca-1) monoclonal antibody (Product # 11-5981-82) in Flow Cytometry
Thu May 28 00:00:00 EDT 2015
Validation of the effects of TGF-β1 on tumor recurrence and prognosis through tumor retrieval and cell mechanical properties.
Cancer cell international
Wu TH,Chou YW,Chiu PH,Tang MJ,Hu CW,Yeh ML
Published figure using Ly-6A/E (Sca-1) monoclonal antibody (Product # 11-5981-82) in Flow Cytometry
Mon Mar 03 00:00:00 EST 2014
Chemotherapy-induced bone marrow nerve injury impairs hematopoietic regeneration.
Nature medicine
Lucas D,Scheiermann C,Chow A,Kunisaki Y,Bruns I,Barrick C,Tessarollo L,Frenette PS
11-5981 was used in Flow cytometry/Cell sorting to demonstrate the potential benefit of adrenergic nerve protection for shielding hematopoietic niches from injury.
Sat Jun 01 00:00:00 EDT 2013
Chemotherapy-induced bone marrow nerve injury impairs hematopoietic regeneration.
Nature medicine
Lucas D,Scheiermann C,Chow A,Kunisaki Y,Bruns I,Barrick C,Tessarollo L,Frenette PS
11-5981 was used in Flow cytometry/Cell sorting to demonstrate the potential benefit of adrenergic nerve protection for shielding hematopoietic niches from injury.
Sat Jun 01 00:00:00 EDT 2013
The nucleotide sugar UDP-glucose mobilizes long-term repopulating primitive hematopoietic cells.
The Journal of clinical investigation
Kook S,Cho J,Lee SB,Lee BC
11-5981 was used in Flow cytometry/Cell sorting to demonstrate a novel mechanism governing the migration of haematopoietic stem progenitor cells under stress.
Thu Aug 01 00:00:00 EDT 2013
A type I IFN-Flt3 ligand axis augments plasmacytoid dendritic cell development from common lymphoid progenitors.
The Journal of experimental medicine
Chen YL,Chen TT,Pai LM,Wesoly J,Bluyssen HA,Lee CK
11-5981 was used in Flow cytometry/Cell sorting to define a critical role for the FL/IFN-I/Flt3 axis in plasmacytoid dendritic cell differentiation from common lymphoid progenitors.
Mon Nov 18 00:00:00 EST 2013
Minor cell-death defects but reduced tumor latency in mice lacking the BH3-only proteins Bad and Bmf.
Oncogene
Baumgartner F,Woess C,Pedit V,Tzankov A,Labi V,Villunger A
11-5981 was used in Flow cytometry/Cell sorting to show that Bad and Bmf co-regulate lymphocyte homeostasis and limit spontaneous transformation in mice.
Thu Jan 31 00:00:00 EST 2013
Distinct temporal requirements for Runx1 in hematopoietic progenitors and stem cells.
Development (Cambridge, England)
Tober J,Yzaguirre AD,Piwarzyk E,Speck NA
11-5981 was used in Flow cytometry/Cell sorting to study how the requirements for Runx1 in erythroid/myeloid progenitors and hematopoietic stem cell formation are temporally distinct.
Sun Sep 01 00:00:00 EDT 2013
A mouse model for inducible overexpression of Prdm14 results in rapid-onset and highly penetrant T-cell acute lymphoblastic leukemia (T-ALL).
Disease models & mechanisms
Carofino BL,Ayanga B,Justice MJ
Published figure using Ly-6A/E (Sca-1) monoclonal antibody (Product # 11-5981-82) in Flow Cytometry
Fri Nov 01 00:00:00 EDT 2013
A non-redundant function of cyclin E1 in hematopoietic stem cells.
Cell cycle (Georgetown, Tex.)
Campaner S,Viale A,De Fazio S,Doni M,De Franco F,D'Artista L,Sardella D,Pelicci PG,Amati B
11-5981 was used in Flow cytometry/Cell sorting to support a role for cyclin E1 in controlling the exit from quiescence in hematopoietic stem cells.
Sun Dec 01 00:00:00 EST 2013
Collagen VI regulates satellite cell self-renewal and muscle regeneration.
Nature communications
Urciuolo A,Quarta M,Morbidoni V,Gattazzo F,Molon S,Grumati P,Montemurro F,Tedesco FS,Blaauw B,Cossu G,Vozzi G,Rando TA,Bonaldo P
11-5981 was used in Magnetic cell separation to demonstrate that collagen VI is a key component of the satellite cell niche.
Mon Dec 30 00:00:00 EST 2013
Association between tumorigenic potential and the fate of cancer cells in a syngeneic melanoma model.
PloS one
Krelin Y,Berkovich L,Amit M,Gil Z
11-5981 was used in Flow cytometry/Cell sorting to compare the tumorigenic potential and cell fate of cells with self-renewing potential in an in vivo melanoma model.
Tue Nov 26 00:00:00 EST 2013
A unique carboxyl-terminal insert domain in the hematopoietic-specific, GTPase-deficient Rho GTPase RhoH regulates post-translational processing.
The Journal of biological chemistry
Troeger A,Chae HD,Senturk M,Wood J,Williams DA
11-5981 was used in Flow cytometry/Cell sorting to demonstrate that deletion of the insert domain (LFSINE) results in significant cytoplasmic protein accumulation in mice.
Fri Dec 20 00:00:00 EST 2013
G-CSF/anti-G-CSF antibody complexes drive the potent recovery and expansion of CD11b+Gr-1+ myeloid cells without compromising CD8+ T cell immune responses.
Journal of hematology & oncology
Rubinstein MP,Salem ML,Doedens AL,Moore CJ,Chiuzan C,Rivell GL,Cole DJ,Goldrath AW
11-5981 was used in Flow cytometry/Cell sorting to evaluate whether the biological activity of G-CSF can be improved by pre-association with anti-G-CSF monoclonal antibodies prior to injection.
Tue Oct 01 00:00:00 EDT 2013
Lunatic fringe deficiency cooperates with the Met/Caveolin gene amplicon to induce basal-like breast cancer.
Cancer cell
Xu K,Usary J,Kousis PC,Prat A,Wang DY,Adams JR,Wang W,Loch AJ,Deng T,Zhao W,Cardiff RD,Yoon K,Gaiano N,Ling V,Beyene J,Zacksenhaus E,Gridley T,Leong WL,Guidos CJ,Perou CM,Egan SE
Published figure using Ly-6A/E (Sca-1) monoclonal antibody (Product # 11-5981-82) in Flow Cytometry
Tue May 15 00:00:00 EDT 2012
Transcription factor RORα is critical for nuocyte development.
Nature immunology
Wong SH,Walker JA,Jolin HE,Drynan LF,Hams E,Camelo A,Barlow JL,Neill DR,Panova V,Koch U,Radtke F,Hardman CS,Hwang YY,Fallon PG,McKenzie AN
11-5981 was used in Flow cytometry/Cell sorting to study how nuocytes arose in the bone marrow and differentiated from common lymphoid progenitors, indicating they are a distinct, previously unknown member of the lymphoid lineage.
Sun Jan 22 00:00:00 EST 2012
Concomitant inactivation of Rb and E2f8 in hematopoietic stem cells synergizes to induce severe anemia.
Blood
Hu T,Ghazaryan S,Sy C,Wiedmeyer C,Chang V,Wu L
Published figure using Ly-6A/E (Sca-1) monoclonal antibody (Product # 11-5981-82) in Flow Cytometry
Thu May 10 00:00:00 EDT 2012
Cis-element mutated in GATA2-dependent immunodeficiency governs hematopoiesis and vascular integrity.
The Journal of clinical investigation
Johnson KD,Hsu AP,Ryu MJ,Wang J,Gao X,Boyer ME,Liu Y,Lee Y,Calvo KR,Keles S,Zhang J,Holland SM,Bresnick EH
Published figure using Ly-6A/E (Sca-1) monoclonal antibody (Product # 11-5981-82) in Flow Cytometry
Mon Oct 01 00:00:00 EDT 2012
CTC1 deletion results in defective telomere replication, leading to catastrophic telomere loss and stem cell exhaustion.
The EMBO journal
Gu P,Min JN,Wang Y,Huang C,Peng T,Chai W,Chang S
Published figure using Ly-6A/E (Sca-1) monoclonal antibody (Product # 11-5981-82) in Flow Cytometry
Wed May 16 00:00:00 EDT 2012
Induction of cardiac myogenic lineage development differs between mesenchymal and satellite cells and is accelerated by bone morphogenetic protein-4.
Journal of molecular and cellular cardiology
Grajales L,García J,Geenen DL
Published figure using Ly-6A/E (Sca-1) monoclonal antibody (Product # 11-5981-82) in Flow Cytometry
Sat Sep 01 00:00:00 EDT 2012
Essential roles for Pot1b in HSC self-renewal and survival.
Blood
Wang Y,Shen MF,Chang S
Published figure using Ly-6A/E (Sca-1) monoclonal antibody (Product # 11-5981-82) in Flow Cytometry
Thu Dec 01 00:00:00 EST 2011
Dynamic variation in cycling of hematopoietic stem cells in steady state and inflammation.
The Journal of experimental medicine
Takizawa H,Regoes RR,Boddupalli CS,Bonhoeffer S,Manz MG
11-5981 was used in Flow cytometry/Cell sorting to investigate how often mouse hematopoietic stem cells (HSCs) divide and whether each HSC contributes simultaneously, sequentially, or repetitively to hematopoiesis, showing that entry into and exit out of the cell cycle is dynamic varies due to demand.
Mon Feb 14 00:00:00 EST 2011
Defective hematopoietic stem cell and lymphoid progenitor development in the Ts65Dn mouse model of Down syndrome: potential role of oxidative stress.
Antioxidants & redox signaling
Lorenzo LP,Chen H,Shatynski KE,Clark S,Yuan R,Harrison DE,Yarowsky PJ,Williams MS
11-5981 was used in Flow cytometry/Cell sorting to identify a link between oxidative stress and diminished IL-7Rα expression and function associated with defective haematologic development in a DS mouse model.
Sat Oct 15 00:00:00 EDT 2011
CD24-positive cells from normal adult mouse liver are hepatocyte progenitor cells.
Stem cells and development
Qiu Q,Hernandez JC,Dean AM,Rao PH,Darlington GJ
Published figure using Ly-6A/E (Sca-1) monoclonal antibody (Product # 11-5981-82) in Flow Cytometry
Thu Dec 01 00:00:00 EST 2011
Adipose-derived stem cells promote lymphangiogenesis in response to VEGF-C stimulation or TGF-β1 inhibition.
Future oncology (London, England)
Yan A,Avraham T,Zampell JC,Haviv YS,Weitman E,Mehrara BJ
Published figure using Ly-6A/E (Sca-1) monoclonal antibody (Product # 11-5981-82) in Flow Cytometry
Thu Dec 01 00:00:00 EST 2011
A high omega-3 fatty acid diet has different effects on early and late stage myeloid progenitors.
Lipids
Varney ME,Buchanan JT,Dementieva Y,Hardman WE,Sollars VE
Published figure using Ly-6A/E (Sca-1) monoclonal antibody (Product # 11-5981-82) in Flow Cytometry
Sat Jan 01 00:00:00 EST 2011
Identification of epidermal progenitors for the Merkel cell lineage.
Development (Cambridge, England)
Woo SH,Stumpfova M,Jensen UB,Lumpkin EA,Owens DM
11-5981 was used in Flow cytometry/Cell sorting to identify a previously undescribed population of epidermal progenitors that reside in the touch domes of hairy skin, termed touch dome progenitor cells.
Wed Dec 01 00:00:00 EST 2010
Delayed enrichment of mesenchymal cells promotes cardiac lineage and calcium transient development.
Journal of molecular and cellular cardiology
Grajales L,García J,Banach K,Geenen DL
Published figure using Ly-6A/E (Sca-1) monoclonal antibody (Product # 11-5981-82) in Flow Cytometry
Thu Apr 01 00:00:00 EDT 2010
Wnt7a activates the planar cell polarity pathway to drive the symmetric expansion of satellite stem cells.
Cell stem cell
Le Grand F,Jones AE,Seale V,Scimè A,Rudnicki MA
Published figure using Ly-6A/E (Sca-1) monoclonal antibody (Product # 11-5981-82) in Flow Cytometry
Fri Jun 05 00:00:00 EDT 2009
Allogeneic stromal cell implantation in brain tissue leads to robust microglial activation.
Immunology and cell biology
Tambuyzer BR,Bergwerf I,De Vocht N,Reekmans K,Daans J,Jorens PG,Goossens H,Ysebaert DK,Chatterjee S,Van Marck E,Berneman ZN,Ponsaerts P
11-5981 was used in Flow cytometry/Cell sorting to describe the immunological mechanism leading to rejection of allogeneic BM-SCs after implantation in murine CNS.
Fri Jun 19 00:00:00 EDT 2009
Locally administered TLR7 agonists drive systemic antitumor immune responses that are enhanced by anti-CD40 immunotherapy.
Journal of immunology (Baltimore, Md. : 1950)
Broomfield SA,van der Most RG,Prosser AC,Mahendran S,Tovey MG,Smyth MJ,Robinson BW,Currie AJ
11-5981 was used in Flow cytometry/Cell sorting to show that locally delivered TLR7 agonist imiquimod in conjuction with systemic anti-CD40 immunotherapy significantly enhances the local antitumor response and retards growth of distal tumors.
Fri May 01 00:00:00 EDT 2009
Reporter gene-expressing bone marrow-derived stromal cells are immune-tolerated following implantation in the central nervous system of syngeneic immunocompetent mice.
BMC biotechnology
Bergwerf I,De Vocht N,Tambuyzer B,Verschueren J,Reekmans K,Daans J,Ibrahimi A,Van Tendeloo V,Chatterjee S,Goossens H,Jorens PG,Baekelandt V,Ysebaert D,Van Marck E,Berneman ZN,Linden AV,Ponsaerts P
11-5981 was used in Flow cytometry/Cell sorting to implant reporter gene-expression bone marrow-derived stromal cells in the central nervous system of syngeneic immunocompetent mice.
Wed Jan 07 00:00:00 EST 2009
Reporter gene-expressing bone marrow-derived stromal cells are immune-tolerated following implantation in the central nervous system of syngeneic immunocompetent mice.
BMC biotechnology
Bergwerf I,De Vocht N,Tambuyzer B,Verschueren J,Reekmans K,Daans J,Ibrahimi A,Van Tendeloo V,Chatterjee S,Goossens H,Jorens PG,Baekelandt V,Ysebaert D,Van Marck E,Berneman ZN,Linden AV,Ponsaerts P
11-5981 was used in Flow cytometry/Cell sorting to implant reporter gene-expression bone marrow-derived stromal cells in the central nervous system of syngeneic immunocompetent mice.
Wed Jan 07 00:00:00 EST 2009
Beta-Catenin downregulation attenuates ischemic cardiac remodeling through enhanced resident precursor cell differentiation.
Proceedings of the National Academy of Sciences of the United States of America
Zelarayán LC,Noack C,Sekkali B,Kmecova J,Gehrke C,Renger A,Zafiriou MP,van der Nagel R,Dietz R,de Windt LJ,Balligand JL,Bergmann MW
11-5981 was used in Flow cytometry/Cell sorting to conclude that beta-catenin depletion attenuates postinfarct left ventricular remodelling through increased differentiation of GATA4(pos)/Sca-1(pos) resident cardiac progenitor cells.
Tue Dec 16 00:00:00 EST 2008
Identification of chromatin remodeling genes Arid4a and Arid4b as leukemia suppressor genes.
Journal of the National Cancer Institute
Wu MY,Eldin KW,Beaudet AL
11-5981 was used in Flow cytometry/Cell sorting to investigate the role of epigenetic alterations in tumorigenesis.
Wed Sep 03 00:00:00 EDT 2008
E47 controls the developmental integrity and cell cycle quiescence of multipotential hematopoietic progenitors.
Journal of immunology (Baltimore, Md. : 1950)
Yang Q,Kardava L,St Leger A,Martincic K,Varnum-Finney B,Bernstein ID,Milcarek C,Borghesi L
11-5981 was used in Flow cytometry/Cell sorting to show E47 controls the developmental integrity and cell cycle quiescence of hematopoietic progenitors.
Sat Nov 01 00:00:00 EDT 2008
Tumor growth decreases NK and B cells as well as common lymphoid progenitor.
PloS one
Richards J,McNally B,Fang X,Caligiuri MA,Zheng P,Liu Y
11-5981 was used in Flow cytometry/Cell sorting to analyse the effects of tumour growth on lymphopoiesis in mice.
Thu Sep 11 00:00:00 EDT 2008
Mast cell lineage diversion of T lineage precursors by the essential T cell transcription factor GATA-3.
Nature immunology
Taghon T,Yui MA,Rothenberg EV
11-5981 was used in Flow cytometry/Cell sorting to assess both Notch-dependent and Notch-independent roles of GATA-3 in monolayer culture systems with OP9 stromal cells.
Wed Aug 01 00:00:00 EDT 2007
