Product References
Polycomb Bodies Detection in Murine Fibromuscular Stroma from Skin, Skeletal Muscles, and Aortic Tissues.
Methods in molecular biology (Clifton, N.J.)
Rosti V,Gorini F,Santarelli P,Sarnicola ML,Magnani S,Lanzuolo C
48-5921-82 was used in Flow cytometry/Cell sorting to combine a fluorescence-activated cell sorter (FACS)-based method with an immunofluorescence staining.
Wed May 24 00:00:00 EDT 2023
Deletion of CD36 exhibits limited impact on normal hematopoiesis and the leukemia microenvironment.
Cellular & molecular biology letters
Meng Y,Pospiech M,Ali A,Chandwani R,Vergel M,Onyemaechi S,Yaghmour G,Lu R,Alachkar H
48-5921-82 was used in Flow cytometry/Cell sorting to investigate whether targeting CD36 has any detrimental impact on normal hematopoietic cells.
Wed May 24 00:00:00 EDT 2023
Deficiency for SAMHD1 activates MDA5 in a cGAS/STING-dependent manner.
The Journal of experimental medicine
Schumann T,Ramon SC,Schubert N,Mayo MA,Hega M,Maser KI,Ada SR,Sydow L,Hajikazemi M,Badstübner M,Müller P,Ge Y,Shakeri F,Buness A,Rupf B,Lienenklaus S,Utess B,Muhandes L,Haase M,Rupp L,Schmitz M,Gramberg T,Manel N,Hartmann G,Zillinger T,Kato H,Bauer S,Gerbaulet A,Paeschke K,Roers A,Behrendt R
48-5921-82 was used in Flow cytometry/Cell sorting to find that the chronic interferon response in SAMHD1-deficient mice was driven by the MDA5/MAVS pathway but required functional priming through the cGAS/STING pathway.
Mon Jan 02 00:00:00 EST 2023
Functional ProTracer identifies patterns of cell proliferation in tissues and underlying regulatory mechanisms.
NPJ Regenerative medicine
Liu X,Han M,Weng W,Li Y,Pu W,Liu K,Li X,He L,Sun R,Shen R,He Y,Liang D,Chen YH,Wang QD,Tchorz JS,Zhou B
48-5921-82 was used in Flow cytometry/Cell sorting to generat Cre-activated functional ProTracer (fProTracer) mice, which enable simultaneous recording of cell proliferation and tissue-specific gene deletion, facilitating broad functional analysis of cell proliferation by any Cre driver.
Thu Aug 03 00:00:00 EDT 2023
Traumatic brain injury stimulates sympathetic tone-mediated bone marrow myelopoiesis to favor fracture healing.
Signal transduction and targeted therapy
Liu W,Chen W,Xie M,Chen C,Shao Z,Zhang Y,Zhao H,Song Q,Hu H,Xing X,Cai X,Deng X,Li X,Wang P,Liu G,Xiong L,Lv X,Zhang Y
48-5921-82 was used in Flow cytometry/Cell sorting to conclude that TBI accelerates bone formation during early stage of fracture healing process by shaping the anti-inflammation environment in the bone marrow.
Wed Jul 05 00:00:00 EDT 2023
p21 facilitates chronic lung inflammation via epithelial and endothelial cells.
Aging
Levi N,Papismadov N,Majewska J,Roitman L,Wigoda N,Eilam R,Tsoory M,Rotkopf R,Ovadya Y,Akiva H,Regev O,Krizhanovsky V
48-5921-82 was used in Flow cytometry/Cell sorting to implicate p21 as a critical regulator of chronic bronchitis and a driver of chronic airway inflammation and lung destruction.
Thu Mar 30 00:00:00 EDT 2023
Maturation and specialization of group 2 innate lymphoid cells through the lung-gut axis.
Nature communications
Zhao M,Shao F,Yu D,Zhang J,Liu Z,Ma J,Xia P,Wang S
48-5921-82 was used in Flow cytometry/Cell sorting to show that ILC2s undergo translocation via the lung-gut axis upon IL-33 treatment.
Fri Dec 09 00:00:00 EST 2022
MDMX acts as a pervasive preleukemic-to-acute myeloid leukemia transition mechanism.
Cancer cell
Ueda K,Kumari R,Schwenger E,Wheat JC,Bohorquez O,Narayanagari SR,Taylor SJ,Carvajal LA,Pradhan K,Bartholdy B,Todorova TI,Goto H,Sun D,Chen J,Shan J,Song Y,Montagna C,Xiong S,Lozano G,Pellagatti A,Boultwood J,Verma A,Steidl U
48-5921-82 was used in Flow cytometry/Cell sorting to identify MDMX overexpression as a pervasive preleukemic-to-AML transition mechanism in different genetically driven disease subtypes, and reveal Wnt/β-Catenin as a non-canonical MDMX-driven pathway with therapeutic potential for progression prevention and cancer interception.
Mon Apr 12 00:00:00 EDT 2021
Dysregulated RASGRP1 expression through RUNX1 mediated transcription promotes autoimmunity.
European journal of immunology
Baars MJD,Douma T,Simeonov DR,Myers DR,Kulhanek K,Banerjee S,Zwakenberg S,Baltissen MP,Amini M,de Roock S,van Wijk F,Vermeulen M,Marson A,Roose JP,Vercoulen Y
48-5921 was used in Flow cytometry/Cell sorting to suggest that RUNX1 is a transcriptional regulator of RASGRP1 expression which is vital to prevent inflammatory disease.
Mon Feb 01 00:00:00 EST 2021
Engineered red blood cells carrying PCSK9 inhibitors persistently lower LDL and prevent obesity.
PloS one
Deshycka R,Sudaryo V,Huang NJ,Xie Y,Smeding LY,Choi MK,Ploegh HL,Lodish HF,Pishesha N
Published figure using TER-119 monoclonal antibody (Product # 48-5921-82) in Flow Cytometry
Fri Dec 24 00:00:00 EST 2021
GRHL3 activates FSCN1 to relax cell-cell adhesions between migrating keratinocytes during wound reepithelialization.
JCI insight
Kashgari G,Venkatesh S,Refuerzo S,Pham B,Bayat A,Klein RH,Ramos R,Ta AP,Plikus MV,Wang PH,Andersen B
Published figure using TER-119 monoclonal antibody (Product # 48-5921-82) in Flow Cytometry
Wed Sep 08 00:00:00 EDT 2021
The IRE1/XBP1 signaling axis promotes skeletal muscle regeneration through a cell non-autonomous mechanism.
eLife
Roy A,Tomaz da Silva M,Bhat R,Bohnert KR,Iwawaki T,Kumar A
Published figure using TER-119 monoclonal antibody (Product # 48-5921-82) in Flow Cytometry
Tue Nov 23 00:00:00 EST 2021
SnRNA sequencing defines signaling by RBC-derived extracellular vesicles in the murine heart.
Life science alliance
Valkov N,Das A,Tucker NR,Li G,Salvador AM,Chaffin MD,Pereira De Oliveira Junior G,Kur I,Gokulnath P,Ziegler O,Yeri A,Lu S,Khamesra A,Xiao C,Rodosthenous R,Srinivasan S,Toxavidis V,Tigges J,Laurent LC,Momma S,Kitchen R,Ellinor P,Ghiran I,Das S
Published figure using TER-119 monoclonal antibody (Product # 48-5921-82) in Flow Cytometry
Wed Dec 01 00:00:00 EST 2021
Hypoxia-sensing CAR T cells provide safety and efficacy in treating solid tumors.
Cell reports. Medicine
Kosti P,Opzoomer JW,Larios-Martinez KI,Henley-Smith R,Scudamore CL,Okesola M,Taher MYM,Davies DM,Muliaditan T,Larcombe-Young D,Woodman N,Gillett CE,Thavaraj S,Maher J,Arnold JN
Published figure using TER-119 monoclonal antibody (Product # 48-5921-82) in Flow Cytometry
Tue Apr 20 00:00:00 EDT 2021
Reticulon-1C Involvement in Muscle Regeneration.
Metabolites
Rossin F,Avitabile E,Catarinella G,Fornetti E,Testa S,Oliverio S,Gargioli C,Cannata S,Latella L,Di Sano F
48-5921-82 was used in Flow cytometry/Cell sorting to suggest that changes in muscle metabolism such as mitochondrial dysfunction and dysregulation of intracellular Ca2+ homeostasis are implicated in many adverse conditions affecting skeletal muscle.
Wed Dec 08 00:00:00 EST 2021
Heterogeneity of murine periosteum progenitors involved in fracture healing.
eLife
Matthews BG,Novak S,Sbrana FV,Funnell JL,Cao Y,Buckels EJ,Grcevic D,Kalajzic I
48-5921-82 was used in Flow Cytometry to demonstrate that the periosteum is highly enriched with skeletal progenitor cells, and there is heterogeneity in the populations of cells that contribute to mature lineages during periosteal fracture healing.
Tue Feb 09 00:00:00 EST 2021
Activation of skeletal muscle-resident glial cells upon nerve injury.
JCI insight
Proietti D,Giordani L,De Bardi M,D'Ercole C,Lozanoska-Ochser B,Amadio S,Volonté C,Marinelli S,Muchir A,Bouché M,Borsellino G,Sacco A,Puri PL,Madaro L
48-5921-82 was used in Flow cytometry/Cell sorting to report on the identification of Itga7-expressing muscle-resident glial cells activated by loss of neuromuscular junction (NMJ) integrity.
Thu Apr 08 00:00:00 EDT 2021
Sex Matters: Physiological Abundance of Immuno-Regulatory CD71+ Erythroid Cells Impair Immunity in Females.
Frontiers in immunology
Mashhouri S,Koleva P,Huynh M,Okoye I,Shahbaz S,Elahi S
Published figure using TER-119 monoclonal antibody (Product # 48-5921-82) in Flow Cytometry
Mon Dec 20 00:00:00 EST 2021
Optimized protocol for immunophenotyping of melanoma and tumor-bearing skin from mouse.
STAR protocols
Krisna SS,Goncalves C,Gagnon N,Huang F,Plourde D,Miller WH,Fritz JH,Del Rincon SV
48-5921-82 was used in Flow cytometry/Cell sorting to determine a protocol for mouse skin isolation and immune cell isolation.
Fri Sep 17 00:00:00 EDT 2021
Inhibition of TGFβ improves hematopoietic stem cell niche and ameliorates cancer-related anemia.
Stem cell research & therapy
Wang B,Wang Y,Chen H,Yao S,Lai X,Qiu Y,Cai J,Huang Y,Wei X,Guan Y,Wang T,Wang J,Xiang AP
Published figure using TER-119 monoclonal antibody (Product # 48-5921-82) in Flow Cytometry
Mon Jan 18 00:00:00 EST 2021
Lef1 restricts ectopic crypt formation and tumor cell growth in intestinal adenomas.
Science advances
Heino S,Fang S,Lähde M,Högström J,Nassiri S,Campbell A,Flanagan D,Raven A,Hodder M,Nasreddin N,Xue HH,Delorenzi M,Leedham S,Petrova TV,Sansom O,Alitalo K
Published figure using TER-119 monoclonal antibody (Product # 48-5921-82) in Flow Cytometry
Fri Nov 19 00:00:00 EST 2021
Lef1 restricts ectopic crypt formation and tumor cell growth in intestinal adenomas.
Science advances
Heino S,Fang S,Lähde M,Högström J,Nassiri S,Campbell A,Flanagan D,Raven A,Hodder M,Nasreddin N,Xue HH,Delorenzi M,Leedham S,Petrova TV,Sansom O,Alitalo K
Published figure using TER-119 monoclonal antibody (Product # 48-5921-82) in Flow Cytometry
Fri Nov 19 00:00:00 EST 2021
Mitochondrial ubiquinol oxidation is necessary for tumour growth.
Nature
Martínez-Reyes I,Cardona LR,Kong H,Vasan K,McElroy GS,Werner M,Kihshen H,Reczek CR,Weinberg SE,Gao P,Steinert EM,Piseaux R,Budinger GRS,Chandel NS
48-5921 was used in Flow cytometry/Cell sorting to indicate that tumour growth requires the ETC to oxidize ubiquinol, which is essential to drive the oxidative TCA cycle and DHODH activity.
Tue Sep 01 00:00:00 EDT 2020
C/EBPα and GATA-2 Mutations Induce Bilineage Acute Erythroid Leukemia through Transformation of a Neomorphic Neutrophil-Erythroid Progenitor.
Cancer cell
Di Genua C,Valletta S,Buono M,Stoilova B,Sweeney C,Rodriguez-Meira A,Grover A,Drissen R,Meng Y,Beveridge R,Aboukhalil Z,Karamitros D,Belderbos ME,Bystrykh L,Thongjuea S,Vyas P,Nerlov C
Published figure using TER-119 monoclonal antibody (Product # 48-5921-82) in Flow Cytometry
Mon May 11 00:00:00 EDT 2020
Transplantation tolerance modifies donor-specific B cell fate to suppress de novo alloreactive B cells.
The Journal of clinical investigation
Khiew SH,Jain D,Chen J,Yang J,Yin D,Young JS,Dent A,Sciammas R,Alegre ML,Chong AS
48-5921 was used in Flow cytometry/Cell sorting to showed that alloreactive B cells were not deleted but rapidly lost their ability to differentiate into germinal center B cells and secrete donor-specific antibodies., by using a murine model of heart tolerance.
Wed Jul 01 00:00:00 EDT 2020
Deregulated Notch and Wnt signaling activates early-stage myeloid regeneration pathways in leukemia.
The Journal of experimental medicine
Kang YA,Pietras EM,Passegué E
Published figure using TER-119 monoclonal antibody (Product # 48-5921-82) in Flow Cytometry
Mon Mar 02 00:00:00 EST 2020
HDAC inhibitors tune miRNAs in extracellular vesicles of dystrophic muscle-resident mesenchymal cells.
EMBO reports
Sandonà M,Consalvi S,Tucciarone L,De Bardi M,Scimeca M,Angelini DF,Buffa V,D'Amico A,Bertini ES,Cazzaniga S,Bettica P,Bouché M,Bongiovanni A,Puri PL,Saccone V
48-5921-82 was used in Flow Cytometry to show that extracellular vesicles (EVs) released by mesenchymal cells (i.e., fibro-adipogenic progenitors-FAPs) mediate microRNA (miR) transfer to muscle stem cells (MuSCs) and that exposure of dystrophic FAPs to HDAC inhibitors (HDACis) increases the intra-EV levels of a subset of miRs, which cooperatively target biological processes of therapeutic interest, including regeneration, fibrosis, and inflammation.
Thu Sep 03 00:00:00 EDT 2020
The lysophospholipase D enzyme Gdpd3 is required to maintain chronic myelogenous leukaemia stem cells.
Nature communications
Naka K,Ochiai R,Matsubara E,Kondo C,Yang KM,Hoshii T,Araki M,Araki K,Sotomaru Y,Sasaki K,Mitani K,Kim DW,Ooshima A,Kim SJ
Published figure using TER-119 monoclonal antibody (Product # 48-5921-82) in Flow Cytometry
Thu Sep 17 00:00:00 EDT 2020
Methylation of a CGATA element inhibits binding and regulation by GATA-1.
Nature communications
Yang L,Chen Z,Stout ES,Delerue F,Ittner LM,Wilkins MR,Quinlan KGR,Crossley M
Published figure using TER-119 monoclonal antibody (Product # 48-5921-82) in Flow Cytometry
Fri May 22 00:00:00 EDT 2020
A RUNX2 stabilization pathway mediates physiologic and pathologic bone formation.
Nature communications
Kim JM,Yang YS,Park KH,Ge X,Xu R,Li N,Song M,Chun H,Bok S,Charles JF,Filhol-Cochet O,Boldyreff B,Dinter T,Yu PB,Kon N,Gu W,Takarada T,Greenblatt MB,Shim JH
Published figure using TER-119 monoclonal antibody (Product # 48-5921-82) in Flow Cytometry
Fri May 08 00:00:00 EDT 2020
A Wnt-mediated transformation of the bone marrow stromal cell identity orchestrates skeletal regeneration.
Nature communications
Matsushita Y,Nagata M,Kozloff KM,Welch JD,Mizuhashi K,Tokavanich N,Hallett SA,Link DC,Nagasawa T,Ono W,Ono N
48-5921-82 was used in Flow cytometry/Cell sorting to further understand how bone marrow stromal cells are activated during regeneration and facilitate osteogenesis.
Thu Jan 16 00:00:00 EST 2020
Integrated Single-Cell Transcriptomics and Chromatin Accessibility Analysis Reveals Regulators of Mammary Epithelial Cell Identity.
Cell reports
Pervolarakis N,Nguyen QH,Williams J,Gong Y,Gutierrez G,Sun P,Jhutty D,Zheng GXY,Nemec CM,Dai X,Watanabe K,Kessenbrock K
48-5921-82 was used in Flow Cytometry to provide a resource to reveal cis/trans-regulatory elements associated with MEC identity and differentiation that will serve as a reference to determine how the chromatin accessibility landscape changes during breast cancer.
Tue Oct 20 00:00:00 EDT 2020
Prrx1 Fibroblasts Represent a Pro-fibrotic Lineage in the Mouse Ventral Dermis.
Cell reports
Leavitt T,Hu MS,Borrelli MR,Januszyk M,Garcia JT,Ransom RC,Mascharak S,desJardins-Park HE,Litzenburger UM,Walmsley GG,Marshall CD,Moore AL,Duoto B,Adem S,Foster DS,Salhotra A,Shen AH,Griffin M,Shen EZ,Barnes LA,Zielins ER,Maan ZN,Wei Y,Chan CKF,Wan DC,Lorenz HP,Chang HY,Gurtner GC,Longaker MT
48-5921-82 was used in Flow Cytometry to identify and characterise a fibroblast subpopulation in the mouse ventral dermis with intrinsic scar-forming potential.
Tue Nov 10 00:00:00 EST 2020
EphrinB2-EphB4 signalling provides Rho-mediated homeostatic control of lymphatic endothelial cell junction integrity.
eLife
Frye M,Stritt S,Ortsäter H,Hernandez Vasquez M,Kaakinen M,Vicente A,Wiseman J,Eklund L,Martínez-Torrecuadrada JL,Vestweber D,Mäkinen T
48-5921 was used in Flow cytometry/Cell sorting to identify the transmembrane ligand EphrinB2 and its receptor EphB4 as critical homeostatic regulators of collecting lymphatic vessel integrity.
Tue Sep 08 00:00:00 EDT 2020
Androgen Receptor Signaling Positively Regulates Monocytic Development.
Frontiers in immunology
Consiglio CR,Gollnick SO
48-5921 was used in Flow cytometry/Cell sorting to investigate the role of androgen signaling in monocytic differentiation with a genetic mouse model of myeloid androgen receptor (AR) knockout (MARKO) and pharmacological inhibition of AR.
Thu Apr 29 00:00:00 EDT 2021
β4GALT1 controls β1 integrin function to govern thrombopoiesis and hematopoietic stem cell homeostasis.
Nature communications
Giannini S,Lee-Sundlov MM,Rivadeneyra L,Di Buduo CA,Burns R,Lau JT,Falet H,Balduini A,Hoffmeister KM
48-5921 was used in Flow cytometry/Cell sorting to identify the conserved B4galt1 gene as a critical regulator of thrombopoiesis in megakaryocytes.
Fri Jan 17 00:00:00 EST 2020
Long-term ex vivo haematopoietic-stem-cell expansion allows nonconditioned transplantation.
Nature
Wilkinson AC,Ishida R,Kikuchi M,Sudo K,Morita M,Crisostomo RV,Yamamoto R,Loh KM,Nakamura Y,Watanabe M,Nakauchi H,Yamazaki S
48-5921 was used in Flow cytometry/Cell sorting to identify polyvinyl alcohol as a functionally superior replacement for serum albumin that is compatible with good manufacturing practice.
Mon Jul 01 00:00:00 EDT 2019
Transcriptional Basis of Mouse and Human Dendritic Cell Heterogeneity.
Cell
Brown CC,Gudjonson H,Pritykin Y,Deep D,Lavallée VP,Mendoza A,Fromme R,Mazutis L,Ariyan C,Leslie C,Pe'er D,Rudensky AY
48-5921 was used in Flow cytometry/Cell sorting to identify two principal cDC2 lineages defined by distinct developmental pathways and transcriptional regulators, including T-bet and RORγt, two key transcription factors known to define innate and adaptive lymphocyte subsets.
Thu Oct 31 00:00:00 EDT 2019
The Bone Marrow Protects and Optimizes Immunological Memory during Dietary Restriction.
Cell
Collins N,Han SJ,Enamorado M,Link VM,Huang B,Moseman EA,Kishton RJ,Shannon JP,Dixit D,Schwab SR,Hickman HD,Restifo NP,McGavern DB,Schwartzberg PL,Belkaid Y
48-5921-82 was used in Flow Cytometry to show that memory T cells collapsed in secondary lymphoid organs in the context of dietary restriction (DR) but dramatically accumulated within the bone marrow (BM), where they adopted a state associated with energy conservation.
Thu Aug 22 00:00:00 EDT 2019
Macrophages fine tune satellite cell fate in dystrophic skeletal muscle of mdx mice.
PLoS genetics
Madaro L,Torcinaro A,De Bardi M,Contino FF,Pelizzola M,Diaferia GR,Imeneo G,Bouchè M,Puri PL,De Santa F
Published figure using TER-119 monoclonal antibody (Product # 48-5921-82) in Flow Cytometry
Tue Oct 01 00:00:00 EDT 2019
Functional Heterogeneity of Mouse Prostate Stromal Cells Revealed by Single-Cell RNA-Seq.
iScience
Kwon OJ,Zhang Y,Li Y,Wei X,Zhang L,Chen R,Creighton CJ,Xin L
48-5921 was used in Flow cytometry/Cell sorting to characterise mouse Prostate stromal cells heterogeneity by single-cell RNA-seq.
Fri Mar 29 00:00:00 EDT 2019
In Situ Modification of Tissue Stem and Progenitor Cell Genomes.
Cell reports
Goldstein JM,Tabebordbar M,Zhu K,Wang LD,Messemer KA,Peacker B,Ashrafi Kakhki S,Gonzalez-Celeiro M,Shwartz Y,Cheng JKW,Xiao R,Barungi T,Albright C,Hsu YC,Vandenberghe LH,Wagers AJ
48-5921 was used in Flow cytometry/Cell sorting to demonstrate in vivo transduction of endogenous tissue stem cells in the muscle, blood, and skin by systemic or local administration of adeno-associated viruses (AAVs) encoding genome-modifying enzymes.
Tue Apr 23 00:00:00 EDT 2019
Myeloid Cells Restrict MCMV and Drive Stress-Induced Extramedullary Hematopoiesis through STAT1.
Cell reports
Gawish R,Bulat T,Biaggio M,Lassnig C,Bago-Horvath Z,Macho-Maschler S,Poelzl A,Simonović N,Prchal-Murphy M,Rom R,Amenitsch L,Ferrarese L,Kornhoff J,Lederer T,Svinka J,Eferl R,Bosmann M,Kalinke U,Stoiber D,Sexl V,Krmpotić A,Jonjić S,Müller M,Strobl B
48-5921 was used in Flow cytometry/Cell sorting to provide genetic evidence that signaling through STAT1 in myeloid cells is required to restrict MCMV at early time points post-infection and to induce compensatory hematopoiesis in the spleen.
Tue Feb 26 00:00:00 EST 2019
Cbl Ubiquitin Ligases Control B Cell Exit from the Germinal-Center Reaction.
Immunity
Li X,Gadzinsky A,Gong L,Tong H,Calderon V,Li Y,Kitamura D,Klein U,Langdon WY,Hou F,Zou YR,Gu H
48-5921-82 was used in Flow Cytometry to show that deleting E3 ubiquitin ligases Cbl and Cbl-b (Cbls) in GC B cells results in the early exit of high-affinity antigen-specific B cells from the GC reaction and thus impaired clonal expansion.
Tue Mar 20 00:00:00 EDT 2018
PPM1D Mutations Drive Clonal Hematopoiesis in Response to Cytotoxic Chemotherapy.
Cell stem cell
Hsu JI,Dayaram T,Tovy A,De Braekeleer E,Jeong M,Wang F,Zhang J,Heffernan TP,Gera S,Kovacs JJ,Marszalek JR,Bristow C,Yan Y,Garcia-Manero G,Kantarjian H,Vassiliou G,Futreal PA,Donehower LA,Takahashi K,Goodell MA
48-5921 was used in Flow cytometry/Cell sorting to establish the clinical relevance of PPM1D mutations in clonal haematopoiesis and the importance of studying mutation-treatment interactions.
Thu Nov 01 00:00:00 EDT 2018
Ribonuclease inhibitor 1 regulates erythropoiesis by controlling GATA1 translation.
The Journal of clinical investigation
Chennupati V,Veiga DF,Maslowski KM,Andina N,Tardivel A,Yu EC,Stilinovic M,Simillion C,Duchosal MA,Quadroni M,Roberts I,Sankaran VG,MacDonald HR,Fasel N,Angelillo-Scherrer A,Schneider P,Hoang T,Allam R
Published figure using TER-119 monoclonal antibody (Product # 48-5921-82) in Immunocytochemistry
Mon Apr 02 00:00:00 EDT 2018
Ribonuclease inhibitor 1 regulates erythropoiesis by controlling GATA1 translation.
The Journal of clinical investigation
Chennupati V,Veiga DF,Maslowski KM,Andina N,Tardivel A,Yu EC,Stilinovic M,Simillion C,Duchosal MA,Quadroni M,Roberts I,Sankaran VG,MacDonald HR,Fasel N,Angelillo-Scherrer A,Schneider P,Hoang T,Allam R
Published figure using TER-119 monoclonal antibody (Product # 48-5921-82) in Immunocytochemistry
Mon Apr 02 00:00:00 EDT 2018
Intranasal delivery of adjuvant-free peptide nanofibers elicits resident CD8+ T cell responses.
Journal of controlled release : official journal of the Controlled Release Society
Si Y,Wen Y,Kelly SH,Chong AS,Collier JH
48-5921 was used in Flow cytometry/Cell sorting to investigate the extent to which self-assembled peptide nanofibers bearing an influenza peptide epitope elicit antigen-specific CD8+ T cell responses when delivered intranasally, and compare these responses with those elicited by subcutaneous immunization.
Sat Jul 28 00:00:00 EDT 2018
Transient loss of venous integrity during developmental vascular remodeling leads to red blood cell extravasation and clearance by lymphatic vessels.
Development (Cambridge, England)
Zhang Y,Daubel N,Stritt S,Mäkinen T
Published figure using TER-119 monoclonal antibody (Product # 48-5921-82) in Immunofluorescence
Thu Feb 08 00:00:00 EST 2018
MyD88 is required for satellite cell-mediated myofiber regeneration in dystrophin-deficient mdx mice.
Human molecular genetics
Gallot YS,Straughn AR,Bohnert KR,Xiong G,Hindi SM,Kumar A
Published figure using TER-119 monoclonal antibody (Product # 48-5921-82) in Flow Cytometry
Mon Oct 01 00:00:00 EDT 2018
Stem cell factor is selectively secreted by arterial endothelial cells in bone marrow.
Nature communications
Xu C,Gao X,Wei Q,Nakahara F,Zimmerman SE,Mar J,Frenette PS
Published figure using TER-119 monoclonal antibody (Product # 48-5921-82) in Flow Cytometry
Fri Jun 22 00:00:00 EDT 2018
Age-specific biological and molecular profiling distinguishes paediatric from adult acute myeloid leukaemias.
Nature communications
Chaudhury S,O'Connor C,Cañete A,Bittencourt-Silvestre J,Sarrou E,Prendergast Á,Choi J,Johnston P,Wells CA,Gibson B,Keeshan K
Published figure using TER-119 monoclonal antibody (Product # 48-5921-82) in Flow Cytometry
Tue Dec 11 00:00:00 EST 2018
Notch Signaling Facilitates In Vitro Generation of Cross-Presenting Classical Dendritic Cells.
Cell reports
Kirkling ME,Cytlak U,Lau CM,Lewis KL,Resteu A,Khodadadi-Jamayran A,Siebel CW,Salmon H,Merad M,Tsirigos A,Collin M,Bigley V,Reizis B
48-5921 was used in Flow cytometry/Cell sorting to examine the role of Notch signalling in the in vitro generation of classical dendritic cells.
Tue Jun 19 00:00:00 EDT 2018
MicroRNA-155 Protects Group 2 Innate Lymphoid Cells From Apoptosis to Promote Type-2 Immunity.
Frontiers in immunology
Knolle MD,Chin SB,Rana BMJ,Englezakis A,Nakagawa R,Fallon PG,Git A,McKenzie ANJ
48-5921 was used in Flow cytometry/Cell sorting to identify a subset of micro-RNAs that are regulated upon group-2 innate lymphoid cells (ILC2) activation, and establish a specific role for miR-155 in regulating ILC2 survival following activation.
Mon Sep 30 00:00:00 EDT 2019
Single-Cell Analysis Identifies LY6D as a Marker Linking Castration-Resistant Prostate Luminal Cells to Prostate Progenitors and Cancer.
Cell reports
Barros-Silva JD,Linn DE,Steiner I,Guo G,Ali A,Pakula H,Ashton G,Peset I,Brown M,Clarke NW,Bronson RT,Yuan GC,Orkin SH,Li Z,Baena E
48-5921 was used in Flow cytometry/Cell sorting to analyse the molecular heterogeneity in basal and luminal prostate compartments.
Tue Dec 18 00:00:00 EST 2018
Matrix stiffness controls lymphatic vessel formation through regulation of a GATA2-dependent transcriptional program.
Nature communications
Frye M,Taddei A,Dierkes C,Martinez-Corral I,Fielden M,Ortsäter H,Kazenwadel J,Calado DP,Ostergaard P,Salminen M,He L,Harvey NL,Kiefer F,Mäkinen T
48-5921 was used in Flow cytometry/Cell sorting to study whether extracellular matrix stiffness impacts lymphatic vascular development.
Tue Apr 17 00:00:00 EDT 2018
A p53 Super-tumor Suppressor Reveals a Tumor Suppressive p53-Ptpn14-Yap Axis in Pancreatic Cancer.
Cancer cell
Mello SS,Valente LJ,Raj N,Seoane JA,Flowers BM,McClendon J,Bieging-Rolett KT,Lee J,Ivanochko D,Kozak MM,Chang DT,Longacre TA,Koong AC,Arrowsmith CH,Kim SK,Vogel H,Wood LD,Hruban RH,Curtis C,Attardi LD
48-5921 was used in Flow cytometry/Cell sorting to analyse pancreatic cancer development in mice expressing p53 transcriptional activation domain mutants.
Mon Oct 09 00:00:00 EDT 2017
Differential cytokine contributions of perivascular haematopoietic stem cell niches.
Nature cell biology
Asada N,Kunisaki Y,Pierce H,Wang Z,Fernandez NF,Birbrair A,Ma'ayan A,Frenette PS
Published figure using TER-119 monoclonal antibody (Product # 48-5921-82) in Flow Cytometry
Wed Mar 01 00:00:00 EST 2017
Gli1+ Mesenchymal Stromal Cells Are a Key Driver of Bone Marrow Fibrosis and an Important Cellular Therapeutic Target.
Cell stem cell
Schneider RK,Mullally A,Dugourd A,Peisker F,Hoogenboezem R,Van Strien PMH,Bindels EM,Heckl D,Büsche G,Fleck D,Müller-Newen G,Wongboonsin J,Ventura Ferreira M,Puelles VG,Saez-Rodriguez J,Ebert BL,Humphreys BD,Kramann R
48-5921 was used in Flow cytometry/Cell sorting to study the cellular origin of bone marrow fibrosis.
Thu Jun 01 00:00:00 EDT 2017
GATA4-dependent organ-specific endothelial differentiation controls liver development and embryonic hematopoiesis.
The Journal of clinical investigation
Géraud C,Koch PS,Zierow J,Klapproth K,Busch K,Olsavszky V,Leibing T,Demory A,Ulbrich F,Diett M,Singh S,Sticht C,Breitkopf-Heinlein K,Richter K,Karppinen SM,Pihlajaniemi T,Arnold B,Rodewald HR,Augustin HG,Schledzewski K,Goerdt S
Published figure using TER-119 monoclonal antibody (Product # 48-5921-82) in Flow Cytometry
Wed Mar 01 00:00:00 EST 2017
ILC2s regulate adaptive Th2 cell functions via PD-L1 checkpoint control.
The Journal of experimental medicine
Schwartz C,Khan AR,Floudas A,Saunders SP,Hams E,Rodewald HR,McKenzie ANJ,Fallon PG
48-5921 was used in Flow cytometry/Cell sorting to study how group 2 innate lymphoid cells regulate adaptive Th2 cell functions.
Mon Sep 04 00:00:00 EDT 2017
GATA Factor-Regulated Samd14 Enhancer Confers Red Blood Cell Regeneration and Survival in Severe Anemia.
Developmental cell
Hewitt KJ,Katsumura KR,Matson DR,Devadas P,Tanimura N,Hebert AS,Coon JJ,Kim JS,Dewey CN,Keles S,Hao S,Paulson RF,Bresnick EH
Published figure using TER-119 monoclonal antibody (Product # 48-5921-82) in Flow Cytometry
Mon Aug 07 00:00:00 EDT 2017
Engineered erythrocytes covalently linked to antigenic peptides can protect against autoimmune disease.
Proceedings of the National Academy of Sciences of the United States of America
Pishesha N,Bilate AM,Wibowo MC,Huang NJ,Li Z,Deshycka R,Bousbaine D,Li H,Patterson HC,Dougan SK,Maruyama T,Lodish HF,Ploegh HL
Published figure using TER-119 monoclonal antibody (Product # 48-5921-82) in Flow Cytometry
Tue Mar 21 00:00:00 EDT 2017
Obesity reversibly depletes the basal cell population and enhances mammary epithelial cell estrogen receptor alpha expression and progenitor activity.
Breast cancer research : BCR
Chamberlin T,D'Amato JV,Arendt LM
Published figure using TER-119 monoclonal antibody (Product # 48-5921-82) in Flow Cytometry
Wed Nov 29 00:00:00 EST 2017
Smooth muscle cell recruitment to lymphatic vessels requires PDGFB and impacts vessel size but not identity.
Development (Cambridge, England)
Wang Y,Jin Y,Mäe MA,Zhang Y,Ortsäter H,Betsholtz C,Mäkinen T,Jakobsson L
48-5921 was used in Flow cytometry/Cell sorting to demonstrate that platelet-derived growth factor B regulates lymphatic smooth muscle cell recruitment in multiple vascular beds.
Sun Oct 01 00:00:00 EDT 2017
Sustained inflammation after pericyte depletion induces irreversible blood-retina barrier breakdown.
JCI insight
Ogura S,Kurata K,Hattori Y,Takase H,Ishiguro-Oonuma T,Hwang Y,Ahn S,Park I,Ikeda W,Kusuhara S,Fukushima Y,Nara H,Sakai H,Fujiwara T,Matsushita J,Ema M,Hirashima M,Minami T,Shibuya M,Takakura N,Kim P,Miyata T,Ogura Y,Uemura A
Published figure using TER-119 monoclonal antibody (Product # 48-5921-82) in Immunohistochemistry
Thu Feb 09 00:00:00 EST 2017
Praja1 E3 ubiquitin ligase promotes skeletal myogenesis through degradation of EZH2 upon p38α activation.
Nature communications
Consalvi S,Brancaccio A,Dall'Agnese A,Puri PL,Palacios D
48-5921 was used in Flow cytometry/Cell sorting to determine that signal-dependent degradation of EZH2, a PRC2 subunit, is a prerequisite for satellite cell differentiation.
Mon Jan 09 00:00:00 EST 2017
CTLA4-Ig in combination with FTY720 promotes allograft survival in sensitized recipients.
JCI insight
Khiew SH,Yang J,Young JS,Chen J,Wang Q,Yin D,Vu V,Miller ML,Sciammas R,Alegre ML,Chong AS
48-5921 was used in Flow cytometry/Cell sorting to suggest inhibiting memory T cell expansion and trafficking into allografts with CTLA4-Ig and FTY720 promotes allograft survival in allosensitized recipients.
Thu May 04 00:00:00 EDT 2017
Age-dependent modulation of vascular niches for haematopoietic stem cells.
Nature
Kusumbe AP,Ramasamy SK,Itkin T,Mäe MA,Langen UH,Betsholtz C,Lapidot T,Adams RH
Published figure using TER-119 monoclonal antibody (Product # 48-5921-82) in Flow Cytometry
Thu Apr 21 00:00:00 EDT 2016
Dissecting Immune Circuits by Linking CRISPR-Pooled Screens with Single-Cell RNA-Seq.
Cell
Jaitin DA,Weiner A,Yofe I,Lara-Astiaso D,Keren-Shaul H,David E,Salame TM,Tanay A,van Oudenaarden A,Amit I
48-5921 was used in Flow cytometry/Cell sorting to establish CRISP-seq as a broadly applicable, comprehensive, and unbiased approach for elucidating mammalian regulatory circuits.
Thu Dec 15 00:00:00 EST 2016
Postnatal lethality and abnormal development of foregut and spleen in Ndrg4 mutant mice.
Biochemical and biophysical research communications
Qu X,Li J,Baldwin HS
Published figure using TER-119 monoclonal antibody (Product # 48-5921-82) in Immunofluorescence
Fri Feb 12 00:00:00 EST 2016
Pdgfrb-Cre targets lymphatic endothelial cells of both venous and non-venous origins.
Genesis (New York, N.Y. : 2000)
Ulvmar MH,Martinez-Corral I,Stanczuk L,Mäkinen T
48-5921 was used in Flow cytometry/Cell sorting to show that Pdgfrb-Cre does not target YS HemEC or YS-derived erythro-myeloid progenitors.
Wed Jun 01 00:00:00 EDT 2016
A cell-autonomous tumour suppressor role of RAF1 in hepatocarcinogenesis.
Nature communications
Jeric I,Maurer G,Cavallo AL,Raguz J,Desideri E,Tarkowski B,Parrini M,Fischer I,Zatloukal K,Baccarini M
Published figure using TER-119 monoclonal antibody (Product # 48-5921-82) in Flow Cytometry
Wed Dec 21 00:00:00 EST 2016
TBP/TFIID-dependent activation of MyoD target genes in skeletal muscle cells.
eLife
Malecova B,Dall'Agnese A,Madaro L,Gatto S,Coutinho Toto P,Albini S,Ryan T,Tora L,Puri PL
48-5921 was used in Flow cytometry/Cell sorting to demonstrate that TBP2 does not replace TBP during muscle differentiation.
Thu Feb 25 00:00:00 EST 2016
PPAR-α and glucocorticoid receptor synergize to promote erythroid progenitor self-renewal.
Nature
Lee HY,Gao X,Barrasa MI,Li H,Elmes RR,Peters LL,Lodish HF
Published figure using TER-119 monoclonal antibody (Product # 48-5921-82) in Flow Cytometry
Thu Jun 25 00:00:00 EDT 2015
Batf3 maintains autoactivation of Irf8 for commitment of a CD8α(+) conventional DC clonogenic progenitor.
Nature immunology
Grajales-Reyes GE,Iwata A,Albring J,Wu X,Tussiwand R,Kc W,Kretzer NM,Briseño CG,Durai V,Bagadia P,Haldar M,Schönheit J,Rosenbauer F,Murphy TL,Murphy KM
48-5921 was used in Flow cytometry/Cell sorting to investigate the role of the transcription factors Batf3 and IRF8 in the development of CD8α(+) conventional dendritic cells (cDCs)..
Wed Jul 01 00:00:00 EDT 2015
Human definitive haemogenic endothelium and arterial vascular endothelium represent distinct lineages.
Nature cell biology
Ditadi A,Sturgeon CM,Tober J,Awong G,Kennedy M,Yzaguirre AD,Azzola L,Ng ES,Stanley EG,French DL,Cheng X,Gadue P,Speck NA,Elefanty AG,Keller G
48-5921 was used in Flow cytometry/Cell sorting to investigate whether haemogenic endothelium represents a subpopulation of arterial vascular endothelium, showing that they represent distinct lineages.
Fri May 01 00:00:00 EDT 2015
Nonvenous origin of dermal lymphatic vasculature.
Circulation research
Martinez-Corral I,Ulvmar MH,Stanczuk L,Tatin F,Kizhatil K,John SW,Alitalo K,Ortega S,Makinen T
48-5921 was used in Flow cytometry/Cell sorting to investigate the origin of murine lymphatic vasculature, showing a significant contribution from nonvenous cells.
Fri May 08 00:00:00 EDT 2015
Cis-regulatory mechanisms governing stem and progenitor cell transitions.
Science advances
Johnson KD,Kong G,Gao X,Chang YI,Hewitt KJ,Sanalkumar R,Prathibha R,Ranheim EA,Dewey CN,Zhang J,Bresnick EH
Published figure using TER-119 monoclonal antibody (Product # 48-5921-82) in Flow Cytometry
Tue Sep 01 00:00:00 EDT 2015
Genome-wide association study follow-up identifies cyclin A2 as a regulator of the transition through cytokinesis during terminal erythropoiesis.
American journal of hematology
Ludwig LS,Cho H,Wakabayashi A,Eng JC,Ulirsch JC,Fleming MD,Lodish HF,Sankaran VG
Published figure using TER-119 monoclonal antibody (Product # 48-5921-82) in Flow Cytometry
Fri May 01 00:00:00 EDT 2015
Mitochondrial ATP transporter Ant2 depletion impairs erythropoiesis and B lymphopoiesis.
Cell death and differentiation
Cho J,Seo J,Lim CH,Yang L,Shiratsuchi T,Lee MH,Chowdhury RR,Kasahara H,Kim JS,Oh SP,Lee YJ,Terada N
Published figure using TER-119 monoclonal antibody (Product # 48-5921-82) in Flow Cytometry
Tue Sep 01 00:00:00 EDT 2015
Brahma is required for cell cycle arrest and late muscle gene expression during skeletal myogenesis.
EMBO reports
Albini S,Coutinho Toto P,Dall'Agnese A,Malecova B,Cenciarelli C,Felsani A,Caruso M,Bultman SJ,Puri PL
48-5921 was used in Flow cytometry/Cell sorting to show that Brahma and Brg1 have distinct functions at discrete stages of muscle differentiation.
Sat Aug 01 00:00:00 EDT 2015
Replication stress caused by low MCM expression limits fetal erythropoiesis and hematopoietic stem cell functionality.
Nature communications
Alvarez S,Díaz M,Flach J,Rodriguez-Acebes S,López-Contreras AJ,Martínez D,Cañamero M,Fernández-Capetillo O,Isern J,Passegué E,Méndez J
Published figure using TER-119 monoclonal antibody (Product # 48-5921-82) in Immunohistochemistry
Mon Oct 12 00:00:00 EDT 2015
In vivo hematopoietic Myc activation directs a transcriptional signature in endothelial cells within the bone marrow microenvironment.
Oncotarget
Franke K,Vilne B,Prazeres da Costa O,Rudelius M,Peschel C,Oostendorp RA,Keller U
48-5921 was used in Flow cytometry/Cell sorting to study the effect of Myc activation on the frequency of different hematopoietic stem/ progenitor cell subsets.
Tue Sep 08 00:00:00 EDT 2015
Heme-mediated SPI-C induction promotes monocyte differentiation into iron-recycling macrophages.
Cell
Haldar M,Kohyama M,So AY,Kc W,Wu X,Briseño CG,Satpathy AT,Kretzer NM,Arase H,Rajasekaran NS,Wang L,Egawa T,Igarashi K,Baltimore D,Murphy TL,Murphy KM
Published figure using TER-119 monoclonal antibody (Product # 48-5921-82) in Flow Cytometry
Thu Mar 13 00:00:00 EDT 2014
Group 2 innate lymphoid cells facilitate sensitization to local, but not systemic, TH2-inducing allergen exposures.
The Journal of allergy and clinical immunology
Gold MJ,Antignano F,Halim TY,Hirota JA,Blanchet MR,Zaph C,Takei F,McNagny KM
48-5921 was used in Flow cytometry/Cell sorting to reveal a critical role for ILC2s in the development of adaptive type 2 responses to local antigen exposure.
Tue Apr 01 00:00:00 EDT 2014
The function of hematopoietic stem cells is altered by both genetic and inflammatory factors in lupus mice.
Blood
Niu H,Fang G,Tang Y,Xie L,Yang H,Morel L,Diamond B,Zou YR
48-5921 was used in Flow cytometry/Cell sorting to demonstrate that inflammatory cytokines and HMGB1 in lupus mice modify hematopoietic stem cells function.
Thu Mar 14 00:00:00 EDT 2013
Cbx4 regulates the proliferation of thymic epithelial cells and thymus function.
Development (Cambridge, England)
Liu B,Liu YF,Du YR,Mardaryev AN,Yang W,Chen H,Xu ZM,Xu CQ,Zhang XR,Botchkarev VA,Zhang Y,Xu GL
Published figure using TER-119 monoclonal antibody (Product # 48-5921-82) in Immunofluorescence
Fri Feb 01 00:00:00 EST 2013
Distinct temporal requirements for Runx1 in hematopoietic progenitors and stem cells.
Development (Cambridge, England)
Tober J,Yzaguirre AD,Piwarzyk E,Speck NA
48-5921 was used in Flow cytometry/Cell sorting to study how the requirements for Runx1 in erythroid/myeloid progenitors and hematopoietic stem cell formation are temporally distinct.
Sun Sep 01 00:00:00 EDT 2013
Concomitant inactivation of Rb and E2f8 in hematopoietic stem cells synergizes to induce severe anemia.
Blood
Hu T,Ghazaryan S,Sy C,Wiedmeyer C,Chang V,Wu L
Published figure using TER-119 monoclonal antibody (Product # 48-5921-82) in Flow Cytometry
Thu May 10 00:00:00 EDT 2012
Zbtb46 expression distinguishes classical dendritic cells and their committed progenitors from other immune lineages.
The Journal of experimental medicine
Satpathy AT,KC W,Albring JC,Edelson BT,Kretzer NM,Bhattacharya D,Murphy TL,Murphy KM
48-5921 was used in Flow cytometry/Cell sorting to identify Zbtb46 as a transcription factor selectively expressed by classical DCs and their committed progenitors.
Mon Jun 04 00:00:00 EDT 2012
Trophoblasts regulate the placental hematopoietic niche through PDGF-B signaling.
Developmental cell
Chhabra A,Lechner AJ,Ueno M,Acharya A,Van Handel B,Wang Y,Iruela-Arispe ML,Tallquist MD,Mikkola HK
Published figure using TER-119 monoclonal antibody (Product # 48-5921-82) in Immunohistochemistry
Tue Mar 13 00:00:00 EDT 2012
CD96 is a leukemic stem cell-specific marker in human acute myeloid leukemia.
Proceedings of the National Academy of Sciences of the United States of America
Hosen N,Park CY,Tatsumi N,Oji Y,Sugiyama H,Gramatzki M,Krensky AM,Weissman IL
48-5921 was used in Flow cytometry/Cell sorting to isolate cell surface molecules expressed on human acute myeloid leukemia-leukemic stem cells.
Tue Jun 26 00:00:00 EDT 2007
Gfi1b alters histone methylation at target gene promoters and sites of gamma-satellite containing heterochromatin.
The EMBO journal
Vassen L,Fiolka K,Möröy T
Published figure using TER-119 monoclonal antibody (Product # 48-5921-82) in Flow Cytometry
Wed Jun 07 00:00:00 EDT 2006
