Dedicated cryo-FIB microscope to prepare cryo-lamellas for cryo-electron tomography

The Thermo Scientific Aquilos 2 Cryo-FIB is dedicated to the preparation of thin, electron-transparent lamellas for high-resolution cellular cryo-electron tomography or MicroED of micro-crystals.  With the Aquilos 2 Cryo-FIB, you can automate steps in the workflow to produce multiple lamellas from specific programmed locations. The improved dedicated cryo-hardware provides longer run times at ultra-low contamination rates. 

Instrument features

Automated batch cryo-lamella milling

Explore state-of-the-art automation for cryo-lamella production and work with challenging bulk-frozen samples that require cryo-lift-out sample preparation.

Correlative fluorescence and electron imaging in one system

The iFLM Correlative System (Integrative Fluorescence Light Microscope) allows you to combine fluorescence imaging and ion milling within a single cryo-FIB SEM microscope.

Aquilos Cryo-FIB resources

Learn more from scientists who are using the Aquilos Cryo-FIB and take a closer look with on-demand webinars and videos.

Cryo-FIB for your lab

Choose the best cryo-focused-ion-beam (cryo-FIB) for your laboratory.  Learn more about other microscope models.

Cryo-ET service and support

To ensure optimal system performance, we provide you access to a world-class network of field service experts, technical support, and workflow validation. 

Explore cryo-electron tomography

The Thermo Scientific cryo-electron tomography (cryo-ET) workflow is a complete end-to-end workflow covering cell culture to flash freezing cells to final 3D visualization and analysis.