Custom Antibody and Protein Bioconjugation Services

1. Request a quote to get in touch with our custom labeling services team. Fill out our form with your antibody or protein information as well as your desired label and labeling chemistry. Our team will provide a quote within 3–5 business days along with a shipping label to mail in your antibody.
2. Send your antibody or protein to our team with the shipping label provided. Our expert team will utilize advanced bioconjugation techniques to efficiently label your antibodies with the desired molecules. Our team will then perform rigorous quality control efforts to help ensure accuracy and reliability of your conjugated antibody or conjugated protein.
3. Receive your conjugate along with its conjugation data from our expert conjugation team.

Our basic conjugation services include standard lysine conjugation, macromolecule crosslinking, and conjugation to beads.

• Standard lysine conjugation utilizes efficient lysine chemistry for reliable labeling with a wide variety of labels. Find the optimal dye for your application and minimize spectral overlap by using our SpectraViewer tool
• Macromolecule crosslinking utilizes conventional amine and/or cysteine chemistry to conjugate large protein biomolecules
• Bead conjugation involves covalent attachment of antibodies or proteins to the bead surface, offering versatility across a range of applications

Our custom bioconjugation capabilities also include Invitrogen SiteClick antibody labeling techniques for highly efficient and site-specific antibody conjugation. SiteClick labeling allows for simple attachment of detection molecules far from the antigen-binding domain, helping provide covalent labeling without altering antibody function. Many detection molecules can be site-selectively attached to antibodies, including:

• Phycobiliproteins (e.g., R-PE and APC)
• Alexa Fluor and pHrodo dyes
• Antibody-drug conjugate toxins
• Biotin
• Metal-chelating compounds
• Qdot probes

We use SiteClick chemistry to create a set of tetravalent bi-specific antibodies. This enables you to choose which pair of antibodies functions best as a bi-specific. Features of our bi-specific custom conjugation offerings include:

• Crosslink any two IgG antibodies
• No genetic engineering required
• Single link between two IgG heavy chains

One-to-one antibody conjugation helps ensure precise labeling with high specificity to enhance accuracy and sensitivity in your detection assays. Our one-to-one custom offerings include:

• RPE for antigen density measurement
• Oligonucleotide for spatial biology or gene therapy
• Brilliant polymer dyes for flow cytometry