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Virus Production Media & Reagents
Accelerate your vaccine and virus production
In today’s vaccine-manufacturing environment, time-to-market and cost effectiveness are critical issues to vaccine producers. Furthermore, reliable scale-up and safety are essential factors for a successful manufacturing process. As a result, performance medium technologies that accelerate vaccine development and streamline manufacturing are now increasingly more important than ever.
Our innovative Gibco product line pioneered commercial serum-free media for vaccine and virus production with its VP-SFM, Dynamis Medium, and OptiPRO SFM medium. Through the elimination of serum in vaccine development processes, Gibco’s vaccine production media can help you mitigate the manufacturing risks, costs, variability and uncertainty related to serum and other animal origin components. In addition, the Gibco vaccine media line supports most common cell lines, including Vero, MDCK, HEK293, BHK-21, MDBK and Sf9/12 among others.
For development processes unable to incorporate serum-free culture, we also offer classical media with the same high-quality manufacturing practices applied to more complex formulations.
GIBCO VP-SFM is a serum-free, animal origin free, ultra-low protein medium designed specifically for the culture of VERO cells.
Cell Types Supported: Vero, COS-7, MDCK, BHK-21, and HEp2
Platform: Adherent Culture (flat culture, micro-carriers)
Application: Vaccines, recombinant proteins and mAb production
Gibco Dynamis Medium is a chemically defined, protein-free, animal origin component-free formulation that supports robust growth of HEK293 cells for adenovirus production.
Cell Types Supported: CHO, HEK293
Platform: Suspension Culture
Application: Adenovirus production
OptiPRO SFM is engineered for the cultivation of a variety of mammalian cell lines used in serum-free, animal origin free conditions. Cell Types Supported: BHK-21, MDCK, MDBK, PK-15, COS-7, HeLa |
Gibco CD BHK-21 Production Medium facilitates regulatory compliance by allowing for high-density suspension growth of BHK-21 cells in a chemically defined (serum free, animal origin free and protein free) environment.
Cell Types Supported: BHK-21, MDCK, MDBK, PK-15, COS-7, HeLa
Platform: Suspension Culture
Application: Vaccines
CD 293 Medium is a chemically-defined, protein-free medium optimized for the growth of suspension cultures of HEK293 cells.
Cell Types Supported: HEK293
Platform: Suspension Culture
Application: Vaccines, gene therapy, viral vectors, recombinant proteins and mAb production
Gibco Sf-900 III SFM is specifically designed to offer high performance and yield using insect cells in both baculovirus and stable expression systems.
Cell Types Supported: Sf9 and Sf21
Platform: Suspension Culture
Application: Vaccines, recombinant proteins and mAb production
Gibco Sf-900 III SFM is specifically designed to offer high performance and yield using insect cells in both baculovirus and stable expression systems.
Cell Types Supported: Sf9 and Sf21 Platform: Suspension Culture Application: Vaccines, recombinant proteins and mAb production
Learn more |
Gibco Sf-900 III SFM is specifically designed to offer high performance and yield using insect cells in both baculovirus and stable expression systems.
Cell Types Supported: Sf9 and Sf21 Platform: Suspension Culture Application: Vaccines, recombinant proteins and mAb production
Learn more |
Gibco Sf-900 III SFM is specifically designed to offer high performance and yield using insect cells in both baculovirus and stable expression systems.
Cell Types Supported: Sf9 and Sf21 Platform: Suspension Culture Application: Vaccines, recombinant proteins and mAb production
Learn more |
Gibco Advanced media are enhanced basal media formulations of DMEM, DMEM/F-12, MEM, and RPMI 1640. Enriched with normal-serum constituents, these media require 50–90% less FBS supplementation, with equivalent or superior cell growth, and no change in morphology or function of many common cell lines.
Cell Types Supported: Various cells
Platform: Adherent Culture (flat culture, micro-carriers)
Application: Vaccines, recombinant proteins and mAb production
Gibco Sf-900 III SFM is specifically designed to offer high performance and yield using insect cells in both baculovirus and stable expression systems.
Cell Types Supported: Sf9 and Sf21 Platform: Suspension Culture Application: Vaccines, recombinant proteins and mAb production
Learn more |
Gibco Sf-900 III SFM is specifically designed to offer high performance and yield using insect cells in both baculovirus and stable expression systems.
Cell Types Supported: Sf9 and Sf21 Platform: Suspension Culture Application: Vaccines, recombinant proteins and mAb production
Learn more |
Gibco Sf-900 III SFM is specifically designed to offer high performance and yield using insect cells in both baculovirus and stable expression systems.
Cell Types Supported: Sf9 and Sf21 Platform: Suspension Culture Application: Vaccines, recombinant proteins and mAb production
Learn more |
Time-tested and trusted, our Gibco classical cell culture media line includes products designed to support the growth and maintenance of a variety of mammalian cells and cell lines. We’ve developed ready-to-use media products as well as powdered and concentrated liquid formulations to fit your experimental setup and your budget. Available formulations include RPMI 1640, MEM, DMEM, Opti-MEM, G-MEM, IMDM, Medium 199, Williams’ Media E and DMEM/F12 among others.
Cell Types Supported: Various cells
Platform: Adherent Culture (flat culture, micro-carriers)
Application: Vaccines, recombinant proteins and mAb production
Gibco Sf-900 III SFM is specifically designed to offer high performance and yield using insect cells in both baculovirus and stable expression systems.
Cell Types Supported: Sf9 and Sf21 Platform: Suspension Culture Application: Vaccines, recombinant proteins and mAb production
Learn more |
Gibco Sf-900 III SFM is specifically designed to offer high performance and yield using insect cells in both baculovirus and stable expression systems.
Cell Types Supported: Sf9 and Sf21 Platform: Suspension Culture Application: Vaccines, recombinant proteins and mAb production
Learn more |
Gibco Sf-900 III SFM is specifically designed to offer high performance and yield using insect cells in both baculovirus and stable expression systems.
Cell Types Supported: Sf9 and Sf21 Platform: Suspension Culture Application: Vaccines, recombinant proteins and mAb production
Learn more |
Supplements and reagents
For cell lines where incorporating animal origin free products is not an option, Gibco offers a number of supplements and reagents that still help eliminate serum from the process.
Albumax is a bovine albumin extracted using a proprietary process to prevent damage to its nutritional capabilities. Bovine transferrin is an important supplement needed when eliminating serum.
We understand that minimizing viral risk is critical for your processes. That’s why both products are sourced and extracted at the same manufacturing facility in New Zealand as our quality FBS products.
TrypLE Select is an animal origin free, recombinant enzyme for dissociating a wide range of adherent mammalian cells.
Cell Types Supported: Various cells
Platform: Adherent Culture (flat culture, micro-carriers)
Application: Vaccines, recombinant proteins and mAb production
Benefits:
- Gentler on cells
- Animal origin free
- Does not share the genetic sequence of porcine trypsin
Gibco GlutaMAX media are standard cell culture media that contain a stabilized form of L-glutamine, the dipeptide L-alanyl-L-glutamine, that prevents degradation and ammonia buildup even during long-term culture. Extremely stable in aqueous solution, the dipeptide does not degrade in storage or incubation, which allows:
- Increased media stability
- Minimized toxic ammonia buildup
- Maximized cell performance
Cell Types Supported: Various cells
Platform: Adherent Culture (flat culture, micro-carriers) and suspension culture
Application: Vaccines, recombinant proteins and mAb production
Gibco Albumax and BSA Fraction V products are bovine albumins produced using a process that does not expose the albumin to high heat giving them superior cell culture performance. These are specialized purified BSA offerings from Gibco specifically designed for cell culture application. Gibco BSA product benefits:
- Sourced from New Zealand
- Several variants available to meet any customer need: Low lipid, Low IgG, Ultra-low IgG.
- Gamma irradiation available as a customization
Cell Types Supported: Various cells
Platform: Adherent Culture (flat culture, micro-carriers)
Application: Vaccines
If your process requires customization, we offer specialty medium formulation assistance and cell culture expertise in modifying our premium Gibco catalog products to match your specific requirements.
The Gibco catalog also offers quality reagents, buffers and supplements for all your virus production needs.
Learn more about Gibco Bioprocessing
Related Resources
Application note: Diploid Growth Serum-Reduced Medium can reduce or eliminate serum use in human and animal vaccine production
Brochure: Vaccine Production Cell Culture
Poster: Development of a chemically defined medium for Escherichia coli, Gibco™ Bacto™ CD Supreme Fermentation Production Medium (FPM) leveraging learnings from traditional peptone-based media
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