Cancer genome sequencing enables researchers to generate comprehensive genetic maps of normal vs. tumor samples and view what types of genetic alterations are driving various forms of cancer. The goal of cancer whole genome sequencing or whole exome (targeted sequencing restricted to the protein-coding subset of cancer genomes) is to identify sequence variants and mutations critical in the development of human cancers. The data generated from cancer whole genome or whole exome sequencing enables researchers to compare and contrast cancer genomes where we might find clues for understanding how to design better drugs for various types of cancers.

Research Interest

 

Applications

 

Challenges

  • Identify new genetic risk factors associated with cancer
  • Catalog and build foundational genetic information about cancer
 
  • Whole genome sequencing
  • Whole exome sequencing
 
  • Long turn around time
  • Inflexible platform—inability to scale
  • Cost prohibitive
 

Life Technologies Solution


Ion Proton™ Sequencer

Sequence whole cancer genomes and whole cancer exomes on a fast, simple, and scalable benchtop device with the Ion Proton™ Sequencer. With two flexible formats, use the Ion Proton™ I Chip for exome sequencing or the higher density Ion Proton™ II Chip for whole genome sequencing.

All products referenced are for Research Uses Only and are not intended for human or animal therapeutic or diagnostic uses.