Multidrop Dispensers | Thermo Fisher Scientific

Versatile automated lab in dispensing for superior ease and precision.

Meet your lab’s needs with outstanding flexibility and performance with the easy-to-use Thermo Scientific Multidrop reagent dispensers. Designed to support the varied requirements for liquid dispensing in pharmaceutical and biotechnology laboratories. Compact Thermo Scientific Multidrop dispensers fit easily on the bench, and the intuitive user interface makes setup and programming a breeze. Fill plates in seconds with excellent precision and reproducibility, helping you run tests faster and increase productivity.

Multidrop Combi

	Multidrop Combi+	Multidrop Combi SMART+	Multidrop Combi nL
User interface	On-board interface or FILLit PC software	On-board interface or FILLit PC software	On-board interface or FILLit PC software
Volume	0.5-2500 µl	0.5-2500 µl	50 nl-50 µl
Volume increments	Small tube dispensing cassette: 0.5–50 μL, in 0.5 μL increments Standard tube dispensing cassette: 5- 2,000 µL in 5 µLuncrements	Small tube dispensing cassette: 0.5–50 μL, in 0.5 μL increments Standard tube dispensing cassette: 5- 2,000 µL in 5 µLuncrements	1nL increments 50-999nL, 10nL increments 1.00-9.99µL, 100nL increments 10.0-50.0µL, FILLit Software 1nL increments
Dispense volume adjustability	Per column	Per column	Per well
Dead volume	< 1 mL volume range: 0.5 - 50 µL <7 mL volume range: >50 µL (it is possible to backflush the reagent into original reservoir to avoid loss of expensive reagent)	< 1 mL volume range: 0.5 - 50 µL <7 mL volume range: >50 µL (it is possible to backflush the reagent into original reservoir to avoid loss of expensive reagent)	<1.2 mL
Plate formats	9- to 1,536-well plates: including 96- ad 384-deep well and tubes in rack format (plate height: 5 - 50 mm)	9- to 1,536-well plates: including 96- ad 384-deep well and tubes in rack format (plate height: 5 - 50 mm)	96-1536 well plates; including 96, 384- tubes in rack format
Plate height adjustment	Automatic	Automatic	Automatic
Automation/robot compatible	Yes	Yes	Yes
Dispensing Technology	Peristaltic pump	Peristaltic pump	Pressurized valve system
Dimensions	14.0 x 8.6 x 12.9 in. (35.6 x 21.8 x 32.8 cm)	14.0 x 8.6 x 12.9 in. (35.6 x 21.8 x 32.8 cm)	14 x 8.6 x 14.8 in 35.5 x 22 x 37.5 cm
Weight	20.1 lb/9.1K	20.1 lb/9.1K	21.2 lb/9.6 kg

*Multidrop Combi SMART+ uses RFID to track cassette usage

Increase your control of Thermo Scientific Multidrop reagent dispensers. Thermo Scientific FILLit Software is an easy-to-use tool that allows rapid development of protocols that can be run directly from the PC or transferred into instrument memory.

Features:

Extensive plate list containing plates from different manufacturers is available for selection.
User can select discrete wells (Multidrop Combi nL), rows (Multidrop Combi nL) or columns for filling
Protocols created by the user can be stored in the database from which they can be executed for further use or modification.
Protocols can also be downloaded to the instrument for stand-alone use or transferred from the Multidrop back to the PC for further modifications.

Download software

The comprehensive line of Thermo Scientific Multidrop dispensing cassettes offers optimal solutions for a wide volume range and a variety of reagents for the best performance and results. Choose between standard and small tube cassettes and SMART+ versions of these, which store dispensing lifetime data.

Download Multidrop Combi Cassette Selection Guide ›

Multidrop Combi

	Multidrop Combi+	Multidrop Combi SMART+	Multidrop Combi nL
User interface	On-board interface or FILLit PC software	On-board interface or FILLit PC software	On-board interface or FILLit PC software
Volume	0.5-2500 µl	0.5-2500 µl	50 nl-50 µl
Volume increments	Small tube dispensing cassette: 0.5–50 μL, in 0.5 μL increments Standard tube dispensing cassette: 5- 2,000 µL in 5 µLuncrements	Small tube dispensing cassette: 0.5–50 μL, in 0.5 μL increments Standard tube dispensing cassette: 5- 2,000 µL in 5 µLuncrements	1nL increments 50-999nL, 10nL increments 1.00-9.99µL, 100nL increments 10.0-50.0µL, FILLit Software 1nL increments
Dispense volume adjustability	Per column	Per column	Per well
Dead volume	< 1 mL volume range: 0.5 - 50 µL <7 mL volume range: >50 µL (it is possible to backflush the reagent into original reservoir to avoid loss of expensive reagent)	< 1 mL volume range: 0.5 - 50 µL <7 mL volume range: >50 µL (it is possible to backflush the reagent into original reservoir to avoid loss of expensive reagent)	<1.2 mL
Plate formats	9- to 1,536-well plates: including 96- ad 384-deep well and tubes in rack format (plate height: 5 - 50 mm)	9- to 1,536-well plates: including 96- ad 384-deep well and tubes in rack format (plate height: 5 - 50 mm)	96-1536 well plates; including 96, 384- tubes in rack format
Plate height adjustment	Automatic	Automatic	Automatic
Automation/robot compatible	Yes	Yes	Yes
Dispensing Technology	Peristaltic pump	Peristaltic pump	Pressurized valve system
Dimensions	14.0 x 8.6 x 12.9 in. (35.6 x 21.8 x 32.8 cm)	14.0 x 8.6 x 12.9 in. (35.6 x 21.8 x 32.8 cm)	14 x 8.6 x 14.8 in 35.5 x 22 x 37.5 cm
Weight	20.1 lb/9.1K	20.1 lb/9.1K	21.2 lb/9.6 kg

*Multidrop Combi SMART+ uses RFID to track cassette usage

FILLit Software

Features:

Extensive plate list containing plates from different manufacturers is available for selection.
User can select discrete wells (Multidrop Combi nL), rows (Multidrop Combi nL) or columns for filling
Protocols created by the user can be stored in the database from which they can be executed for further use or modification.
Protocols can also be downloaded to the instrument for stand-alone use or transferred from the Multidrop back to the PC for further modifications.

Download software

Cassettes

Download Multidrop Combi Cassette Selection Guide ›

Featured videos

Multidrop Combi+ and Multidrop Combi Smart+ reagent dispensers for easy, quick, precise dispensing.

Get a look inside the Multidrop Combi+ and Combi SMART+

View 3D tour ›

Note: This tool is best viewed in Chrome, Firefox or Safari Browsers. Learn more ›

Multidrop Combi nL provides accurate, reliable low volume dispensing in the range of 50nL to 50µL.

	Multidrop Pico 8	Multidrop Pico 1
User interface	PicoIT PC software	PicoIT PC software
Volumes	11 pL - 20 µl or 1 nL - 200 µl	11 pL - 20 µl or 1 nL - 200 µl
Plate formats	12, 24, 48, 96, 384, 1536 well plate	12, 24, 48, 96, 384 well plate
Plate height adjustment	Automatic	Manual
Automation/robot compatible	Yes	No
Dispensing Technology	Non-contact digital dispensing	Non-contact digital dispensing
Application	Drug combination studies, Biochemical assays, Cell-based assays, DMPK, Secondary screening, Synthetic chemistry, assay development, qPCR, Enzyme profiling, Antibody therapies, SAR, and Spotting
Dimensions	47 x 38 x 32 cm	31 x 28 x 20 cm
Weight	14.1 kg	5.9 kg

An easy-to-use Multidrop PicoIT software platform with application-focused wizards and a highlighted loading guide allows effortless and quick plate setup and operation. Available in one- and eight-well formats to support different throughputs and amounts of reagents and samples.

Download software

Download demo software

The pre-programmed protocols provide:

Pre-selected fluid information
Simplified layout including Non-Template Controls
Pre-set reaction volume and plate type
Pre-set number of replicates

Multidrop Pico

	Multidrop Pico 8	Multidrop Pico 1
User interface	PicoIT PC software	PicoIT PC software
Volumes	11 pL - 20 µl or 1 nL - 200 µl	11 pL - 20 µl or 1 nL - 200 µl
Plate formats	12, 24, 48, 96, 384, 1536 well plate	12, 24, 48, 96, 384 well plate
Plate height adjustment	Automatic	Manual
Automation/robot compatible	Yes	No
Dispensing Technology	Non-contact digital dispensing	Non-contact digital dispensing
Application	Drug combination studies, Biochemical assays, Cell-based assays, DMPK, Secondary screening, Synthetic chemistry, assay development, qPCR, Enzyme profiling, Antibody therapies, SAR, and Spotting
Dimensions	47 x 38 x 32 cm	31 x 28 x 20 cm
Weight	14.1 kg	5.9 kg