Vaccine Development with qPCR and dPCR

Overview

Accelerate the development and manufacturing of mRNA and protein-based vaccines by leveraging Applied Biosystems QualTrak real-time PCR and digital PCR tools for biopharma. Incorporate these highly-sensitive and accurate technologies into workflows across your pipeline for applications in gene expression, genotyping, contaminant testing, and more.

QualTrak vaccine workflow

Discover a new way to navigate qPCR and dPCR workflows throughout vaccine development—from discovery through cGMP manufacturing.

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App Note: QuantStudio 7 Pro qPCR systems

See how QuantStudio systems and consumables generate consistent results across instruments and operators to help ensure data concordance.

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White Paper: QualTrak biopharma ecosystem

Learn how the curated QualTrak offering of qPCR and dPCR instruments, reagents, and assays can help streamline biologics development.

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QualTrak qPCR & dPCR digital experience

qPCR and dPCR have use-cases across vaccine development and manufacturing workflows. Navigate suggested workflows, products, and support options in the QualTrak digital experience.

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Use-cases in the mRNA and protein-based vaccines pipeline

Discovery

Antigen identification

Lead antigen selection

Antibody screening

Biomarker identification

Biomarker screening

Process development

Plasmid construction and mRNA packaging (mRNA vaccines)

Vector construction, cell growth, and protein purification (protein vaccines)

Quality Control test development

Scale-up

In-process test development

Impurity and contamination testing

Residual host-cell DNA

Pre-clinical and clinical trials

Pharmacokinetics & pharmacodynamics studies

Potency testing

Biodistribution analysis

cGMP manufacturing

In-process testing and lot release

Impurity and contamination testing

Viral clearance

Bioburden

Residual host-cell DNA

QualTrak resources for mAb development

Find out how partnering with Thermo Fisher Scientific can connect you to the qPCR & dPCR tools and solutions you need to streamline your pipeline - from discovery through cGMP manufacturing.

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