Molecular Biology Spotlight Articles

Empower your research success with practical molecular biology applications

Get meaningful results at the bench with practical tips and tricks! This collection features various molecular biology applications for PCR, cloning, reverse transcription, and more. We highlight the latest scientific breakthroughs and constantly look for new advancements to help fulfill your research needs.

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Featured Spotlight Articles

Oligos for novel molecular research beyond PCR

High quality and flexible oligo design is important for many molecular biology applications and processes.

CRISPR-mediated genome editing using Golden Gate and Gateway

Cloning methods help enable CRISPR-Cas9 genome editing in plants.

Innovations in biotech diagnostic development and manufacturing

Lyophilization has the potential to simplify testing procedures, making them more accessible.

Search all articles by application categories

Our article collection provides great options to optimize your experiments. Use one of the following buttons for a preset search.

All Isothermal amplification Molecular cloning Nucleic acid electrophoresis Oligos PCR Plastics Restriction and modifying Reverse transcription Synthetic biology

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Category	Article
Nucleic acid electrophoresis	Running in Circles? A Faster Way to Analyze circular RNAs Get a birds-eye view on the generation of circular RNA, its promise in therapeutics, and potential role in pathology. Learn about effective tools to analyze circRNA.
Isothermal Amplification	Unveiling Biotech Diagnostic Manufacturing Ecosystems Biotech diagnostic manufacturing ecosystems face unique regulation, technological, supply chain, and cost challenges but can drive advancements in healthcare and diagnostics, benefitting patients.
Isothermal Amplification	Biotech Diagnostic Development and Manufacturing Innovations Lyophilization is emerging as a game-changer for diagnostic manufacturers because of its impact on sustainability and ability to help democratize access to affordable point-of-care testing.
Oligos	Oligos For Novel Molecular Research Beyond PCR High quality and flexible oligo design is important for many molecular biology applications and processes.
Molecular cloning	CRISPR-Mediated Genome Editing Using Golden Gate and Gateway Cloning Cloning methods help enable CRISPR-Cas9 genome editing in plants.
Plastics	Are All Plastic PCR Tubes Created Equal? Everything you need to know about delivering exceptional results with quality PCR Tubes.
Synthetic biology	Expedited Workflows for Novel Antibody Discovery Learn why bispecific and other novel antibody modalities are the new hot topic in biologic therapies and how gene optimization and transient expression services can save time in the discovery process.
Synthetic biology	Solving real-world problems with synthetic DNA Synthetic biology allows exceptional flexibility to engineer proteins for solving complex problems
PCR	Techniques Supporting Exosome Research and Applications Impacting diagnostic and therapeutic research with molecular biology fundamentals
PCR	A Common Support between Various Omes in Multi-omics Research Molecular Biology is fundamental to the multi-omics approaches and trending applications
PCR	Single-Cell Analysis—Uncovering Diversity and Granularity in Molecular Biology Sensitive methods strengthen single-cell strategy and study of heterogeneity in cell population
Synthetic Biology	GeneOptimizer: Accelerating Discovery Helping labs to maximize protein yields, mRNA expression, and therapeutic protein production
Nucleic acid electrophoresis	Better Late Than Never, but Never Late is Better: Enabling Molecular Biology Research with Facilitated Workflows Learn how leveraging precast agarose gels maximize time and cost savings overtime compared to traditional pour your own gel methods.
Nucleic acid electrophoresis	The E-Gel Power Snap Plus Electrophoresis System Time-savings solution for high-throughput labs with SYBR Safe precast gels
PCR	Disease Detection and Genomics Research in Agriculture Increase plant and animal productivity using digital tools with limited water and land
Restriction and modifying	Powerful Applications for RNA and DNA Modifying Enzymes Basic tools critical to advance biological discovery, diagnostic, and therapeutic research
Plastics	Identifying a Reliable Laboratory Plastics Partner PCR and qPCR plastics quality is critical to consistent and reproducible results
PCR	Understanding Molecular Biology’s Most Unsung Reagents Vital role of dNTPs makes the ability to amplify, modify and fabricate DNA possible.
Isothermal amplification	Lyophilization Enables Point-of-Care Diagnostics Fast, more accessible raw materials for diagnostic test development
PCR	Personalize Skincare: Genomics and In Vitro Testing are Changing the Beauty Industry Review of rising industry trends and the importance of the modern assays and technologies behind them
Reverse transcription	Overcoming hurdles in cDNA synthesis Three ways to boost reverse transcriptase enzyme performance
Plastics	qPCR Plates Selection Guide Four key questions to consider when picking the right qPCR and PCR Plates
PCR	Overcoming Obesity with Adipocyte Research in Yucatan, Mexico Your trade-in instrument can find a second home to help support life-changing research
Plastics	High-Throughput qPCR Plastics Four overlooked essential tips to help maximize the workflow success
Oligos	Best Oligonucleotide Purification Methods From basic genetics and genomics R&D to diagnostics and biotherapeutics
Molecular cloning	Optimize Your DNA Ligation Seven must-have tips to help attain successful ligation reactions
Molecular cloning	Three Ways Gibson Assembly Strengthens CRISPR Workflows Learn how Gibson Assembly is streamlining the use of CRISPR in several applications
Plastics	Complete Practical Guide to PCR Plate Sealing Everything you need to know to help you pick the right seal and finish experiment strong
Restriction and modification	Scarless cloning of larger DNA sequences with Type IIS Restriction Enzymes FastDigest Type IIS Restriction Enzymes are powerful tools to enable seamless cloning
Molecular cloning	Deconvoluting Viral Biology and Anti-Viral Drug Discovery with Bioassays Quickly recreate aspects of real-world infection in a controlled environment
Molecular cloning	Viral RNA and Protein Expression Methods to clone and express viral genes
Reverse transcription	Viral Infection Through Host Genetics Lens Overview of how hosts respond to viral infection
PCR	Viral Surveillance and Life Cycle Research: The Essential Work Empowering Public Health Learn about strategies for viral surveillance and viral life cycle studies
PCR	Thermal cyclers and the woes of non-linear optimization Learn more about the benefits of VeriFlex technology in thermal cyclers to enable optimizing PCR reactions
Reverse transcription	The Pivotal Role of Reverse Transcriptase in Infectious Disease Surveillance Accurate RNA virus variant detection is critical to help the emerging mutation trend
Reverse transcription	Importance of Robust Reverse Transcriptase in Wastewater-Based Epidemiology Reliable RNA biomarker detects virus monitoring effectively
Reverse transcription	Understanding the Molecular Evolution of a Reverse Transcriptase Directed evolution can help build a better reverse transcriptase
Isothermal amplification	The long and short of isothermal amplification Learn the advantages of LAMP and WGA
Isothermal amplification	Facilitating isothermal amplification-based point of care diagnostics by improved reagents by Thermo Fisher Scientific Explore how the new Bst polymerase for loop-mediated isothermal amplification as a viable alternative to point-of-care testing development
PCR	Equipping Research that Helps Cultivate Healthy Crops in West Africa "Planting the seeds" for hardy, healthy foods
PCR	Microbial Bioremediation of Soil Contamination in Namibia Donate and be an instrument of change
PCR	Three questions to ask when choosing a PCR enzyme Consider high-fidelity enzymes for accuracy, high-processivity enzymes for long templates, and hot-start enzymes for specificity
PCR	Genotype them gently Direct PCR master mixes for animal-friendly genotyping
PCR	How is hot-start technology beneficial for your PCR? Hot-start technology and benefits for excellent PCR
PCR	PCR infographic Infographic on the polymerase chain reaction
PCR	Basic principles of qRT-PCR Build a strong foundation
PCR	Perfect for fast and robust routine PCR Phire Hot Start II DNA polymerase
PCR	The power of two Fusion DNA polymerases.
PCR	Optimizing T_m and annealing Using the T_m calculator
Plastics	Ultimate high-performance PCR consumables Armadillo PCR plates
Molecular cloning	Checking your T4 DNA ligase activity Two easy-to-do control experiments
PCR	The history of PCR The evolution of DNA polymerases
Molecular cloning	Molecular cloning infographic Fun facts on molecular cloning
Molecular cloning	Thermo Scientific cloning workflow Choose the right tools
Molecular cloning	Five screening methods every scientist should know Verify that your gene of interest was successfully cloned
Molecular cloning	Five cloning shortcuts from Thermo Scientific Streamline your workflow with these cloning tools
Molecular cloning	A T7 mission for high yields of RNA transcripts TranscriptAid T7 high yield transcription kit
Nucleic acid electrophoresis	Forget the powder! TopVision agarose tablets
Nucleic acid electrophoresis	Eight Tips on How to Improve Gel Electrophoresis Results Improve your electrophoresis results
Nucleic acid electrophoresis	Ambient shipping–decrease packaging waste Thermo Scientific DNA ladders
Restriction and modifying	176 restriction enzymes, 1 buffer FastDigest restriction enzymes
Restriction and modifying	Seven common issues with restriction digestion reactions and how to avoid them
Molecular cloning	DNA Cloning Tips—Build clones with DNA fragments using Gibson Assembly Helpful guidelines for building a single cloning construct
PCR	Six Critical Factors to Help You Choose The Right Thermal Cycler Not all thermal cyclers are created the same
PCR	How to Simplify PCR Optimization Steps for Primer Annealing Introducing a universal annealing temperature for primers
PCR	Quick Mouse Genotyping—Six PCR Tips How to complete sample to gel results in less than an hour
Oligos	Using Oligos in Research Learn about oligos, available modification categories, and ordering options
Oligos	Oligo Design and Ordering Tips Walk through basic tips and tricks to help design and order oligos
RT-PCR	Overcome Four Sample Challenges During RT-PCR Address common challenges in RT-PCR with these recommended solutions
RT-PCR	Difference Between One-Step and Two-Step RT-PCR Which RT-PCR approach is right for your experiment?
PCR	Customer Story: Savoring the Individuality of a Cell Dr. Mandovi Chatterjee and her team uncover the secrets found within a single cell
PCR	Customer Story: Keeping Our Food Supply Safe Beverly Wood and her team are dedicated to protecting consumers from animal borne illnesses
PCR	Customer Story: A Lifetime Fascination with Plant Development Dr. Stan Roux digs into the effects of environmental factors on plant growth and development.
PCR	Customer Story: Messaging Innovation to the Innovators Jason Amsbaugh’s degree in biochemistry was the starting point for a passion to communicate with scientists

Resources

Molecular Biology Resource Library

Access valuable support for standard molecular biology techniques from our library of webinars, videos, articles, and more.

Molecular Biology Web Tools

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