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MarrowMAX™ medium far outperforms commercially available formulations supplemented with giant cell tumor (GCT) conditioned media (Figure 1), providing consistent lot-to-lot performance (Figure 2) with a higher mitotic index and superior chromosome morphology.
Figure 1 - Superior performance of MarrowMAX™ medium. Cells were cultured in: basal medium without conditioned medium; MarrowMAX™ medium; supplier medium (GCT-CM 1); and supplier 2 medium (GCT-CM 2) (both supplier 1 and supplier 2 media contain GCT-conditioned medium). Mitotic cells were assayed 24 hrs after plating. |
Figure 2 - Consistency of MarrowMAX™ medium. Normal bone marrow mononuclear cells were seeded at 1x106 cells/ml in 4 different lots of MarrowMAX™ medium. BrdU updake was measured by absorbance at 405 nm. Results are mean ± SEM for n = 10. |
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