Reagent-Free Ion Chromatography with Eluent Generation (RFIC-EG)

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• What is RFIC-EG?
• Which systems have RFIC-EG capabilities?
• How does RFIC-EG work?
• What eluent generator cartridges are available?
• For more information

Systems with reagent-free IC eluent generation (RFIC-EG) automatically generate high-purity hydroxide, carbonate, bicarbonate, or methanesulfonic acid (MSA) eluents electrolytically using Thermo Scientific Dionex EGC Eluent Generator Cartridges. All that’s needed on an RFIC-EG system is a high-purity source of deionized water. The system will automatically generate eluent at the concentration you indicate for use in isocratic or gradient methods. This means that gradient analyses can be accomplished using an isocratic pump. Eluent is purified inline using a Thermo Scientific Dionex CR-TC Continuously Regenerated Trap Column, and suppressed electrolytically before detection without the need to prepare regenerants.

• RFIC-EG capabilities are integrated in the Thermo Scientific Dionex ICS-6000 HPIC system, Thermo Scientific Dionex Integrion HPIC system, and Thermo Scientific Dionex Inuvion with RFIC system.
• Thermo Scientific Chromeleon Chromatography Data System (CDS) is required to control RFIC-EG system operations. 

Most apparently, RFIC-EG saves time and labor. However, generating eluent electrolytically also makes IC simpler, more powerful, and more reliable. Compared to manual eluent preparation, RFIC-EG provides superior results by preventing baseline shift, increasing sensitivity, improving resolution, and ensuring consistent peak integration. Eliminates manual preparation of eluents or regenerants

• Eliminates errors and variability from manual eluent preparation
  • Saves time
  • Reduces operator exposure to hazardous chemicals
• Improves analytical consistency and reproducibility, day-to-day, system-to-system, lab-to-lab
  • Eliminates start-up or equilibration time
  • Provides uniform, highly stable eluent concentrations
  • Generates highly reproducible results, with little variability in peak retention times or areas
• Reduces the need for calibration
  • Verify system performance quickly just by running a check standard.
• Enables gradient separation with an isocratic pump
• Uses only 15mL water/day translates into 5.2L water/year
• Reduces pump maintenance; pump is only exposed to only deionized (DI) water

With a Dionex EGC installed, just add water to electrolytically produce high-purity hydroxide, carbonate, or methanesulfonic acid eluents for isocratic and gradient runs. Eluents are purified online using the Dionex CR-TC Continuously Regenerated Trap Columns. This line of trap columns removes contaminants, thereby eliminating trace ionic impurities, such as carbonate, from the eluent stream. The traps eliminate the need for off-line cleanup procedures. The Dionex CR-ATC and Dionex CR-CTC trap columns are for removing anionic and cationic contaminants, respectively. Eluents are suppressed electrolytically just prior to detection, thereby eliminating the need to prepare regenerants.