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Celebrating over 25 years of innovation in real-time PCR

As a leader in PCR innovation, we offer you the gold standard in real-time PCR instrumentation. With our Applied Biosystems real-time PCR platforms, you get true value with excellent performance, reliability, and world-class support. Designed for compatibility with Applied Biosystems TaqMan Assays and the flexibility of unlimited real-time chemistry choices, we make it easy for you to get started with your experiments. The Applied Biosystems QuantStudio family of instruments enables you to obtain the results you need, connect and collaborate with colleagues, and achieve your research goals.

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Which real-time or digital PCR system is right for you?

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Compare real-time and digital PCR systems

Fixed block real-time PCR systems
 Simply accessible for new usersSimple to use for all levels of experienceEasy controls for optimized experiments
 
 

 

 

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Reactions per Run969696 or 384
Block Format96-Well-0.2 mL (isothermal)96-Well 0.2-mL or 96-Well Fast 0.1-mL96-Well 0.2-mL, 96-Well Fast 0.1-mL, or 384-Well
Color Combinations (Multiplexing)Up to 3Up to 496-well up to 21
384-well up to 5
Run TimeApproximately 40 minAs fast as 30 minAs fast as 30 min
Programmable Volumes1-200 μL
Validated volumes
10-100 μL		10-100 µl (96-well 0.2mL)

10-30 µl (96-well 0.1mL)		10-100 µl (96-well 0.2mL)

10-30 µl (96-well 0.1mL)

5-20 µl (384-well)
Automation CompatibleNoNoNo
Remote Monitoring
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On-Board MemoryYes, >2,000 runs
Email Notification
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Assist with 21 CFR Part 11 Compliance  Security, auditing, e-signature package included
SensitivityDown to 1 copy
Dynamic RangeUp to 10 logs**
ChemistryAll real-time PCR-based chemistries.  Flexibility for chemistries with or without passive reference dye.
Applications Available:
 
GeneExpression
 
 
 
Genotyping
 
 
 
Copy Number Variation
 
 
 
Protein Detection
 
 
 
MicroRNA
 
 
 
Pathogen Detection
 
 
 
HRM   
IVD PlatformNoNoAvailable in certain countries
Temperature Uniformity± 0.4°C
Excitation SourceOptiFlex™ System with white LED light
Filters/Colors3 excitation filters (450-600 nm)
3 emission filters (500-640 nm)		4 excitation filters (450–600 nm)
4 emission filters (500–640 nm)		96-well: 6 excitation filters (450–670 nm)
6 emission filters (500–720 nm)

384-well: 5 excitation filters (450–650 nm)
5 emission filters (500–700 nm)
Cloud-enabled systemDirect connection
Wi-Fi ConnectivityYes
SizeW 27 cm
D 50 cm
H 40 cm
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Interchangeable block real-time PCR systems
 High flexibility and intuitive designSmart and connectedHigh versatility and intuitive designSmarter productivityMaximum throughput, flexibility, and scalability
 
 

 

 

 

 

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Colors5 colors with OptiFlex5 colors with OptiFlex6 colors with OptiFlex (21 filter combinations)6 colors with OptiFlex (21 filter combinations)6 colors with OptiFlex (21 filter combinations)
Reactions per Run96 or 38496 or 38496 or 38496 or 38496, 384, or 12,228
Interchangeable block formats96-well (0.1 and 0.2 mL), 384-well96-well (0.2 mL), 384-well96-well (0.1 and 0.2 mL), 384-well, TaqMan Array96-well (0.2 mL), 384-well96-well (0.1 and 0.2 mL), 384-well, TaqMan Array, OpenArray
ThroughputHighHighHighHighVery High
Dimensions (H x W x D)73.8 x 50.1 x 66.1 cm52.5 x 33.8 x 54.7 cm73.8 x 50.1 x 66.1 cm52.5 x 33.8 x 54.7 cm73.8 x 50.1 x 66.1 cm
VeriFlex temperature controlN/AYes, 3 zonesN/AYes, 6 zonesN/A
Excitation SourceHalogen lampBright white LEDHalogen lampBright white LEDWhite LED
SensitivityDown to 1 copy
Dynamic RangeUp to 10 logs**
21 CFR Part 11-enablementOptional security, auditing, e-signature packageNoOptional security, auditing, e-signature packageSecurity, auditing, e-signature package †Optional security, auditing, e-signature package
Touch screenYesYes, interactiveYesYes, interactiveYes
Cloud-enabled systemNoYesNoYesNo
Run TimeAs fast as 30 min
ChemistryAll real-time PCR-based chemistries. Flexibility for chemistries with or without passive reference dye.
Applications Available: 
GeneExpression
 
 
 
 
 
Genotyping
 
 
 
 
 
Copy Number Variation
 
 
 
 
 
Protein Detection
 
 
 
 
 
MicroRNA
 
 
 
 
 
Pathogen Detection
 
 
 
 
 
HRM
 
 
 
 
 
IVD PlatformNoNoAvailable in certain countriesNoNo
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*Duplex capabilities with OpenArray and multiplex capabilities for other formats.
**Up to 7 logs with OpenArray.
† Module available in 2020

Digital PCR system
 Powerfully Simple Digital PCR
 
 

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Reactions per run16 per plate
Format20,000 microchambers per sample
Color combinations (multiplexing)4 (endpoint detection)
Run time~90 minutes per run
Validated volumes9 µL per reaction
Assists with 21 CFR Part 11 compliance?Yes
SensitivityDown to 1 copy
Dynamic range5 logs
ChemistryTaqMan
Applications availableRare mutation detection, quantification of molecular standards, copy number variation, absolute quantification, pathogen detection,  digital PCR
IVD platformNo
SizeW 60 cm
D 62 cm
H 54 cm
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Service and support for real-time PCR systems

Service and support for fixed block real-time PCR systems

 
 

 

Warranty information
1-year standard warranty  
 
 
Service plans available post warranty
AB Complete
 
 
AB Assurance
 
 
AB Maintenance
 
 
Planned Maintenance
 
 
Compliance services  
IQ/OQ/PQ or IPV
 
 
OQ/PQ or IPV
 
 


Service and support for interchangeable block real-time PCR systems

 
 

 

 

 

 

Warranty information
1-year standard warranty  
 
 
 
 
 
Service plans available post warranty
AB Complete
 
 
 
 
 
AB Assurance
 
 
 
 
 
AB Maintenance
 
 
 
 
 
Planned Maintenance
 
 
 
 
 
Compliance services  
IQ/OQ/PQ or IPV
 
 
 
 
 
OQ/PQ or IPV
 
 
 
 
 
CSV
 
 
 
 
 


Service and support for digital PCR systems

 
 

Warranty information
1-year standard warranty 
 
Service plans available post warranty
AB Assurance
 
Smart Start orientation
 
Customer Concierge services
 
Rapid Exchange
 
Compliance services
IQ/OQ/IPV
 
OQ/IPV
 
SAE IQ/OQ
 

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Instrument connectivity
 QuantStudio 1*, 3 & 5 systemsQuantStudio 6 & 7 Pro systems
Instrument status  
Monitor run over smart phone (ICMA)  
Experiment Design App (DA)  
Data analysis modules (SC, RQ, PA, GT, HRM)  
Voice commands  
Smart Help  
Smart remote support  
Instrument scheduler  

*QuantStudio 1 system is not available in the US and Canada.

Learn more about connected instruments and how they can help to accelerate your science.

Find the parts you need as well as part numbers for our legacy real-time PCR systems.

A wide range of software applications to help you get the most from your Applied Biosystems real-time PCR system.

Select your real-time PCR (qPCR) instrument from the drop-down menu, and easily find the plates, optical caps, and optical seals compatible with your instrument.

Applied Biosystems Spectral Calibration Kits and TaqMan® RNase P Instrument Verification Plates to help calibrate and verify the performance of your real-time PCR system.

Applied Biosystems Thermal Cyclers

Looking for a thermal cycler for end-point PCR?

Resources

Support

For Research Use Only. Not for use in diagnostic procedures.