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Beyond discovery

All-in-one nano-, capillary-, and micro-flow LC for your high-sensitivity LC-MS workflows

Beyond innovation

Accelerating your productivity with long-term, trouble-free operation at maximum performance

Beyond possibilities

Enabling LC-MS experts and novice users to get high-quality results, every time

Learn more  Product specifications

Need the same great results, faster?

Introducing the Vanquish Neo Tandem Direct Injection Workflow

  • Increased sample throughput while maintaining data quality from 100 nL/min to 100 µL/min
  • Decreased carryover with extended washing cycles
  • Simplified hardware and method setup provide the same great user experience

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Learn how the Vanquish Neo UHPLC system can bring value to your lab.

Discover why the Vanquish Neo UHPLC system is the new standard in low-flow LC.

Learn how the Vanquish Neo UHPLC system accelerates new discoveries and productivity.

All-in-one low-flow UHPLC system

  • ProFlow XR technology delivers excellent retention time precision from nano up to 100 μL/min at pressures up to 1500 bar
  • Industry-leading flow-pressure footprint enables high-resolution separations on ultra-long columns and high throughput

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Maximum performance

  • Next-generation SmartInject technology drives retention time precision, column lifetime, and ESI stability
  • Automated multi-wash procedures improve low-level analyte sensitivity
  • Vial bottom detection enables precise and accurate injections with minimal sample waste

 Learn more

Enhanced productivity

  • Fast sample loading and column equilibration improves sample throughput and MS utilization
  • Unique split-loop autosampler design minimizes sample dispersion and sample waste while enhancing workflow versatility
  • The tandem direct injection workflow provides maximized sample throughput and mass spectrometer utilization

 Learn more

Versatile LC-MS workflows

  • Seamless integration with the Thermo Scientific mass spectrometry portfolio through a comprehensive suite of ESI sources
  • Optimized configurations including direct and tandem direct injection, and trap-and-elute workflows ensure superior performance and system versatility

 Learn more

Intelligent operation

  • The Vanquish User Interface improves your user experience by providing walk-up and remote system monitoring, control, and automated procedures
  • The method editor wizard ensures compatibility of method parameters with installed consumables

 Learn more

All-in-one low-flow UHPLC system

All-in-one low-flow UHPLC system

  • ProFlow XR technology delivers excellent retention time precision from nano up to 100 μL/min at pressures up to 1500 bar
  • Industry-leading flow-pressure footprint enables high-resolution separations on ultra-long columns and high throughput

 Learn more

Maximum performance

Maximum performance

  • Next-generation SmartInject technology drives retention time precision, column lifetime, and ESI stability
  • Automated multi-wash procedures improve low-level analyte sensitivity
  • Vial bottom detection enables precise and accurate injections with minimal sample waste

 Learn more

Enhanced productivity

Enhanced productivity

  • Fast sample loading and column equilibration improves sample throughput and MS utilization
  • Unique split-loop autosampler design minimizes sample dispersion and sample waste while enhancing workflow versatility
  • The tandem direct injection workflow provides maximized sample throughput and mass spectrometer utilization

 Learn more

Versatile LC-MS workflows

Versatile LC-MS workflows

  • Seamless integration with the Thermo Scientific mass spectrometry portfolio through a comprehensive suite of ESI sources
  • Optimized configurations including direct and tandem direct injection, and trap-and-elute workflows ensure superior performance and system versatility

 Learn more

Intelligent operation

Intelligent operation

  • The Vanquish User Interface improves your user experience by providing walk-up and remote system monitoring, control, and automated procedures
  • The method editor wizard ensures compatibility of method parameters with installed consumables

 Learn more

Drive your science forward by incorporating the Vanquish Neo UHPLC system into a workflow with other Thermo Scientific products, including our low-flow (U)HPLC columns, industry-leading mass spectrometers, and a software platform that streamlines your laboratory processes.

Low-flow (U)HPLC columns
 

Thermo Scientific PepMap Neo and µPac Neo columns help researchers achieve excellent sample coverage and result reproducibility.

Thermo Scientific Orbitrap Astral mass spectrometer

The Thermo Scientific Orbitrap Astral mass spectrometer enables you to dramatically expand the scale and scope of your proteomics experiments.

Thermo Scientific Stellar
mass spectrometer

The Thermo Scientific Stellar Mass Spectrometer offers a combination of robust quantitation and the specificity of rapid full scan MSn acquisition.

Thermo Scientific Ardia Platform

The Thermo Scientific Ardia Platform connects and organizes projects, people, and instruments, on a global level to support your lab’s digital transformation.

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