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Cryo-EM is continuing to revolutionize our understanding of cancer and cancer treatments. Over the past several years, scientists are using cryo-EM in remarkable ways to uncover new cancer pathways, obtain atomic-level descriptions of key cancer proteins, and provide a framework for improving pharmaceutical interventions. Cryo-EM allows researchers to freeze biomolecules in their native conformations and visualize protein interactions. Scientists can use cryo-EM to capture different stages of biochemical reactions instead of just the pre-reaction and end states. With structural insights, researchers can better understand the conditions required for cancer cell growth and identify new ways to treat cancer.
Watch, read, or listen as we sit down with some of your peers using cryo-EM to discover how the technology is helping them gain a better understanding of cancer.
Harnessing the power of cryo-EM for discovery of cancer therapeutics: High-resolution structures of the human CDK-activating kinase bound to inhibitors.
Cryo-Electron Microscopy and the Complexity of Cancer
Dr. Simon Poepsel of UC Berkeley explains how single-particle cryo-electron microscopy enables us to gain insight into cancer development through the detailed analysis of molecular structure, covering both biology and methodology.
Read the "Understanding the complexity of cancer with cryo-EM" eBook to explore:
Download eBook: Understanding the complexity of cancer with Cryo-EM
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