Krios G4 Cryo-TEM Features

Solve structures at record-breaking resolutions

Pair the Thermo Scientific Krios G4 Cryo-TEM with the Thermo Scientific E-CFEG and the groundbreaking Thermo Scientific Selectris and Selectris X Imaging Filters to advance cryo-EM discovery with unprecedented resolution, speed, and ease of use. The E-CFEG is a cold field emission gun with a narrow energy spread that results in higher contrast images and enables atomic resolution. This add-on makes it possible to efficiently solve structures at resolutions of 2.0 Å or less.

 

Selectris Imaging Filters provide unique stability, accessibility, and performance. Paired with the Thermo Scientific Falcon 4i Direct Electron Detector, these two add-ons produce better quality images up to 10 times faster than the previous generation.

Krios G4 Cryo-TEM benefits

Truly atomic resolution performance

The optional Selectris X Imaging Filter with Falcon 4i Direct Electron Detector and E-CFEG cold field emission source improve image contrast to reach higher resolutions in shorter time.

Maximized productivity through automation

Advanced Performance Monitoring ensures the best optical starting point for automated runs and Thermo Scientific Smart EPU Software 
enables automated grid screening, quality monitoring, and data management.

Workflow connectivity


Designed for easy exchange of cassettes, facilitating a smooth transfer of specimens between Autoloader-equipped TEM instruments, and equipped with Thermo Scientific Athena Software to manage experimental parameters and data.

Easier to fit into new or existing labs

Redesigned internal base frame and system enclosure reduce height below 3 m (10 ft) while enhancing system performance and preventing costly room renovations.

Krios G4 Cryo-TEM features

Upgrade options available for previous Krios Cryo-TEM generations

Electron source: cold field emission gun (E-CFEG)

 

E-CFEG is a low-energy spread cold field emission gun for higher contrast at truly atomic resolution. Low energy spread (≤0.3 eV) enables higher contrast at high resolutions (≤2.0 Å); Improved contrast at high spatial frequencies to reach higher resolutions in less time.

Detectors, cameras, optical modules, and software

 

Increase your lab’s productivity and performance with innovative upgrades:

Accelerate your pathogen research with the 60°C heat decontamination solution

 

Empower your lab with the new 60°C heat decontamination for the Krios G4 cryo-TEM. This accessory enables pathogen research and comprehensive instrument service in higher biosafety-level containment facilities (e.g. BSL3), so you can help make the world cleaner, safer, and healthier.

Krios G4 Cryo-TEM technical specifications

Krios Cryo TEM Datasheet

Selectris and Selectris X Imaging Filters

Falcon 4i Direct Electron Detector

For Research Use Only. Not for use in diagnostic procedures.