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Cell Isolation With Dynabeads and MagniSort Technology
Gentle, tube-based magnetic separation with Invitrogen Dynabeads or MagniSort beads are technologies of choice when you want to isolate high yields of pure, viable and functional cells. Magnetic separation helps ensure that the isolated cells are not affected by passage through a dense column and that the cells’ native characteristics are preserved.
Dynabeads cell isolation products
Human cell isolation
- Directly from whole blood, MNC, buffy coat, bone marrow or tissue samples.
Mouse cell isolation
- Directly from bone marrow, spleen, lymph node or thymus
Cell isolation using your own antibody
- Dynabeads magnetic beads are used for cell isolations from a range of different species and cell subsets
Positive isolation
- Ideal for flow-analysis and cell-based assays
- When maximum purity and yield is critical
Negative isolation
- Truly untouched cells, bead- and antibody-free
- In perfect shape for any application
- High yield, purity and viability
Depletion
- Easy removal of unwanted cell types
- Ideal for positive cell isolation for molecular applications
- High yield and purity
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Negative cell isolation
In negative isolation, Dynabeads are used to deplete all the unwanted cells using the supplied antibody mix. Your bead-free and untouched target cells are left in the sample, and can be directly analyzed in a flow cytometer and used in any functional assay.
Should you want to refine for a particular cell type, you can of course add extra antibodies to the antibody mix.
Depletion
In depletion, cell-specific Dynabeads are used to remove specific unwanted cell types from a mixed cell sample with >99% efficiency. Recover the depleted supernatant—containing all your cells of interest—for downstream assays.
For human cell depletion:
For mouse cell depletion:
You can also use the positively targeted and bead-bound cells for downstream molecular applications that do not require release of cells.
The Two Worlds of Cell Separation
The Two Worlds of Cell Separation
An entertaining and useful explanation of the differences between the micro- and nano-particle techniques used for cell isolation / cell separation.
MagniSort cell isolation products
Starting with T cell-specific cocktails, use the MagniSort platform to obtain enriched T cells simpler, faster and with significant cost-savings compared to traditional column-based separation methods.
For Research Use Only. Not for use in diagnostic procedures.