Antibody Fragmentation Kits

We offer optimized reagents and kits based on immobilized papain, pepsin, and ficin proteases to selectively cleave IgG and IgM immunoglobulin molecules into Fab, Fab′, F(ab′)2 and Fc antibody fragments for use in immunodetection and immunoassay procedures.

Fab preparation kits

Digest human or mouse IgG antibodies with immobilized papain protease and purify Fab fragments using Protein A agarose.

F(ab′)2 preparation kits

Selectively digest whole human and other IgG antibodies with immobilized pepsin protease to make F(ab′)2 fragments that retain antigen binding activity.

Mouse IgG1 Fab and F(ab′)2 preparation kits

Efficiently digest mouse IgG1 antibodies into Fab or F(ab′)2 fragments with immobilized ficin protease.