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Genomics and transcriptomics approaches for improved cancer biomarker discovery and verification

Research into cancer genomics and transcriptomics is advancing our understanding of cancer development and progression. Genomics approaches for biomarker discovery can lead to the identification and validation of potential diagnostic, predictive, prognostic, and therapeutic cancer biomarkers in the future.

Overcome the biggest challenges in cancer research

Thermo Fisher Scientific offers a variety of cancer genomics and transcriptomics solutions to help you solve the most urgent challenges in cancer research today:

  • Uncover cryptic tumor heterogeneity
  • Extract data from limited and challenging samples, such as FFPE tissues or cell-free DNA (cfDNA) samples
  • Obtain key insights from vast amounts of data generated by multiple technologies
  • Choose the right technology for each stage of biomarker discovery and verification

Cancer research areas
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Solid tumor profiling for improved stratification

Extract more information from your FFPE samples with a multi-omic approach by combining somatic mutation and copy number variation profiling, fusion gene analysis, and transcriptome profiling using our NGS, Sanger sequencing, microarray, and qPCR solutions.

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Liquid biopsy analysis for identification and monitoring of genomic abnormalities

Track genomic abnormalities, such as somatic mutations, copy number variations, and fusion genes, even against the background of dynamic tumor heterogeneity in cell-free nucleic acid (cfNA) samples with our targeted NGS and digital PCR assays.

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Immuno-oncology biomarker discovery beyond PD-1/PD-L1

Discover the next-generation of biomarkers to enable better patient stratification with best-in-class tools for the analysis of tumor mutation burden (TMB), T cell receptor (TCR) repertoire, microsatellite instability (MSI), chromothripsis, tumor aneuploidy, and more.

Cancer research guidebook

Updated Cancer research guidebook

Learn how to maximize funding, save time, save precious samples, and more.

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Updated Immuno-Oncology (I-O) guide snapshots

Updated Immuno‑oncology (I‑O) guide

Discover key I‑O research approaches, including checkpoint inhibitor therapy research, CAR T cell therapy research, and cancer vaccine therapy research.

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Cancer genomics and transcriptomics solutions

With access to these flexible and proven solutions, you can uncover the genetic variants and RNA signatures you need to power your next cancer research breakthrough.

Targeted NGS solutions for cancer research

Accelerate your cancer research with our Oncomine assays and Ion AmpliSeq technology and panels.

Liquid biopsy analysis

The Oncomine cfNA assays and TaqMan Liquid Biopsy dPCR assays together offer a comprehensive set of tools for liquid biopsy applications from broad detection of cancer biomarkers to rapid, precise monitoring of a targeted set of mutations.

Cancer genotyping and cytogenetics

Detect chromosomal alterations and somatic mutations that drive cancer as well as germline mutations associated with cancer risk using NGS, Sanger sequencing, microarrays, and qPCR.

Cancer epigenetics

Identify epigenetic changes that occur during tumor progression.

Whole-genome copy number analysis

Microarrays are the platform of choice for detecting copy number variations (CNVs) such as insertions, deletions, loss-of-heterozygosity (LOH), copy neutral LOH, chromothripsis, and more.

Cancer RNA expression

Choose from a variety of RNA expression solutions for fast, simple analysis of coding as well as short and long noncoding RNAs to uncover new RNA-based cancer biomarkers.

Whole exome sequencing

Discover new biomarkers for cancer research using exome sequencing, a simple and fast approach for the identification of rare mutations.

Laser capture microdissection

Isolate pure populations of cancer cells from tumor tissues for more efficient and accurate results with downstream techniques such as NGS, Sanger sequencing, microarrays, and qPCR.

For Research Use Only. Not for use in diagnostic procedures.