Boost Consistency and Yields in Your Veterinary Vaccine Production with an Optimized Peptone Mix

Your peptone mix is critical for maximizing vaccine yield and quality.

Small changes in selection may lead to significant impacts on performance –  don't leave your peptone mix to chance.

Why your peptone mix matters

In veterinary vaccine production, even small variations in your peptone mix can lead to significant differences in both yield and consistency. Peptones are biologically derived, meaning each batch can subtly affect the growth of fastidious and non-fastidious organisms. For veterinary vaccines, this can make or break your production goals – from production efficiency to the quality of your final product.

5 considerations & questions to ask when selecting your peptone mix

Whether you’re just beginning your vaccine development or still in the planning stages, understanding how peptone variability affects your work is critical. 

 

An optimized peptone mix can make all the difference in the success of your vet vaccine. 

The benefits of an optimal peptone mix

Helps maximize yield efficiency

An optimized peptone mix provides essential nutrients, ensuring robust microbial growth and higher vaccine yields. It can also help reduce variability in production, leading to more reliable batch-to-batch performance.

Consistent vaccine quality

Peptones with the right balance of nitrogen and other key nutrients can help support predictable cell growth, reducing fluctuations that can compromise vaccine quality. Consistency in your peptone mix helps maintain potency and stability in your final product.

Helps reduce downtime and rework

Inefficiencies or inconsistencies in your peptone mix may lead to batch failures or require rework, costing time and resources. Help maintain a smooth and interrupted production process with a reliable peptone mix. 

Improved process scalability

As your production scales, so do the demands of your fermentation process. An optimized peptone mix can help you replicate success at larger scales, with reliable results across all production sizes.

Ensure your new vaccine is supported with the optimal peptone mix from the beginning. Schedule a consultation to meet one-on-one with one of our experienced R&D team members. 

Understanding peptone types and their role in veterinary vaccine development

Animal-Derived Peptones

Sourced from animal tissues like meat and organs, these peptones are nutrient-rich, particularly in nitrogen, and often preferred for fastidious organisms.

 

Pros: 

  • Rich nutrient profile with a wide range of amino acids and growth factors
  • Well established in fermentation processes
  • May be lower cost than animal origin free peptones

 

Cons:

  • Higher risk of contamination from animal sources (e.g. BSE)
  • Higher regulatory scrutiny

Plant-Derived Peptones

Made from soy, wheat, or other plant materials, these peptones offer greater consistency and lower contamination risk.

 

Pros: 

  • Lower risk of contamination (BSE) 
  • May support regulatory compliance for reduced animal origin content
  • Production can be more sustainable vs AO

 

Cons:

  • May offer a limited nutritional profile
  • Possible requirement of supplementation with additional growth factors 

Interested in a consultation? Here’s how our process works:

Submit your request

Fill out our consultation request form and we’ll match you with a dedicated account manager to help meet your needs. 

Discovery call

Your account manager will set up a discovery call to understand your goals, challenges, and current peptone selection process.

R&D evaluation

You will meet with our R&D team for a 1:1 consultation, aligning your specific needs with a tailored peptone mix. 

Recommendations & support

Receive personalized recommendations from our experienced team members designed to help optimize your peptone mix and drive consistent, high-yield results.

Trusted by leaders in veterinary vaccine development, just like you.

“For peptone, we trust one of the major brands in the market, [Thermo Scientific]. They provide a variety of good-quality peptones. The consistency and composition of peptone must be precise, which can only be attained if the producer is following strict manufacturing and sourcing protocols. [Thermo Fisher Scientific] ensures it provides high-quality products [consistency, formulation of the peptone, and ingredients they are manufacturing] through strict protocols, which I think, make them stand out. ”

 

-R&D professional, USA

“Thermo Fisher [Scientific is one of the] best for animal-origin peptone. The peptones produced by [other companies] comply with the standards. Thermo Fisher [Scientific] always maintains the consistency of its ingredients.”

 

- R&D professional, USA

Interested in learning more about veterinary vaccines?

New insights: Animal health and vet vaccine trends

The landscape of animal health is undergoing significant changes, especially in the context of bacterial infections and vaccine development. Take a look at our latest article Animal Health Trends & Vet Vaccines in 2025 to explore key trends in animal health, focusing on bacterial infections, the benefits of vaccination versus treatment, the role of peptones in vaccine fermentation, and how to evaluate your peptone mix for optimal efficacy.

Peptones for veterinary vaccine fermentation

With over 100 years of culture media manufacturing experience, from raw materials to final product and powered by our peptones, we offer the expertise, quality assurance and scale to ensure successful microbial vaccine production.

 

Our Thermo Scientific Oxoid peptones are available in both animal-origin and animal-origin-free options, offering a range of AN/TN ratios to suit the specific needs of your process.

For Research Use Only. Not for use in diagnostic procedures.