Mitochondrial Marker Antibodies

Mitochondria are membrane-bound organelles enclosed by a dual membrane. The outer membrane is relatively smooth; however, the inner membrane has many folds (cristae) that significantly increase the surface area of the inner membrane. These cristae are the site of ATP synthesis in which the energy from glucose is converted to ATP by oxidative phosphorylation. This process provides the cell’s principal energy source, giving it the power to carry out all of its varied functions. Mitochondria also contain their own ribosomes and DNA. While mitochondria primarily provide energy, they are also involved in cellular tasks like signaling, differentiation, apoptosis, and the control of the cell cycle and growth.

Mitochondrial marker antibodies detect proteins specific to the mitochondria and can aid in the study of the morphology and dynamics of the mitochondria. Mitochondrial marker antibodies can also help elucidate the role or roles a protein may play in a number of tasks that are centered in or influenced by the mitochondria. Invitrogen mitochondrial marker antibodies are designed to dependably detect the key mitochondrial targets. Each antibody is validated for use in various applications. Key mitochondrial marker targets include:

Each Invitrogen mitochondrial marker antibody is validated for use in applications such as ELISA, western blot, flow cytometry, immunofluorescence, immunohistochemistry, immunocytochemistry, and immunoprecipitation.