Search Thermo Fisher Scientific
SelectScreen Kinase Profiling Services
Expect and receive high quality kinase profiling data in days and accelerate your lead discovery projects with our SelectScreen Kinase Profiling Services.
Labs from pharmaceutical, biotech, consumer goods, and academic institutions have utilized SelectScreen Kinase Profiling Service since their initiation in 2004.
Our kinase panel has just expanded! Over 485 kinase assays now available for screening and profiling. See the Broad Assay Panel tab below for the full listing.
Fast data delivery
The Accelerated Data Delivery™ service returns up to 80% of your kinase profiling data to you in as little as 48 hours
Customer Testimonials
Why do scientists trust the SelectScreen Services team?
- Average data delivery time of just 5 days—so you can get data to your medicinal chemists more quickly
- Access data in real-time—as soon as it is available—via our secure online portal
- Broad panel of more than 485 purified kinases—to help you establish how selective a compound is to its intended targets
- State-of-the-art compound management system ensures consistently high quality data is delivered for every project
- Complete Lab Information Management System (LIMS) ensures project traceability and consistency
Project options
Customize your kinase profiling project to get the right data for your research.
Standard service options include:
- Targets – >485 available biochemical assays
- Mode – Single point concentrations and IC50 and/or EC50 determinations
- Choice of ATP concentration – 10µM, 100µM, and Km [app] ATP (activity assays only)
For the kinases that are available in our activity assays, comprehensive titrations are performed against our panel of available substrates. In addition, ATP titrations are performed for each of these kinases to determine the Km[app] ATP for each target. As a result, you can choose to have your compound run at, above, or below the Km[app] ATP for each kinase within the panel that utilizes an activity assay. This flexibility allows you to identify specific types of inhibitors with various mechanisms of action.
To discuss your kinase profiling project requirements, send us an inquiry
Personalized support
From project beginning to end, you can rely on our Drug Discovery Services project management team to provide frequent project communication via a single point of contact.
Watch this two-minute video to see how our project managers and technical specialists create an exceptional experience for our customers. Submit order
Technology overview
Currently, two different assay platforms are available for profiling – activity and binding. The Z′-LYTE and Adapta kinase activity assays are used most extensively for profiling and a smaller subset of kinases may be profiled using our LanthaScreen Eu Kinase Binding Assays.
Overview of available formats
| Z′-LYTE | Technology Overview | Protocol and Assay Conditions |
| Adapta | Technology Overview | Protocol and Assay Conditions |
| LanthaScreen Eu Kinase Binding Assay | Technology Overview | Protocol and Assay Conditions |
A stringent validation process ensures the highest quality data possible with each data point performed in duplicate. Strict quality control protocols ensure that any assay results not meeting set specifications will be automatically repeated, this includes a control inhibitor titration (IC50) for each kinase on every plate.
To discuss your kinase profiling project requirements, send us an inquiry.
Broad assay panel
| Kinase | Activity assays | Binding assay | |
|---|---|---|---|
| Z′-LYTE | Adapta | LanthaScreen | |
| AAK1 | |||
| ABL1 | |||
| ABL1 E255K | |||
| ABL1 F317I | |||
| ABL1 F317L | |||
| ABL1 G250E | |||
| ABL1 H396P | |||
| ABL1 M351T | |||
| ABL1 Q252H | |||
| ABL1 T315I | |||
| ABL1 Y253F | |||
| ABL2 (Arg) | |||
| ACVR1 (ALK2) | |||
| ACVR1 (ALK2) R206H | |||
| ACVR1B (ALK4) | |||
| ACVR2A | |||
| ACVR2B | |||
| ACVRL1 | |||
| ADCK3 | |||
| ADRBK1 (GRK2) | |||
| ADRBK2 (GRK3) | |||
| AKT1 (PKB alpha) | |||
| AKT2 (PKB beta) | |||
| AKT3 (PKB gamma) | |||
| ALK | |||
| ALK C1156Y | |||
| ALK F1174L | |||
| ALK L1196M | |||
| ALK R1275Q | |||
| ALK T1151_L1152insT | |||
| AMPK (A1/B1/G2) | |||
| AMPK (A1/B1/G3) | |||
| AMPK (A1/B2/G1) | |||
| AMPK (A1/B2/G2) | |||
| AMPK (A1/B2/G3) | |||
| AMPK (A2/B1/G2) | |||
| AMPK (A2/B1/G3) | |||
| AMPK (A2/B2/G1) | |||
| AMPK (A2/B2/G2) | |||
| AMPK (A2/B2/G3) | |||
| AMPK A1/B1/G1 | |||
| AMPK A2/B1/G1 | |||
| AURKA (Aurora A) | |||
| AURKB (Aurora B) | |||
| AURKC (Aurora C) | |||
| AXL | |||
| AXL R499C | |||
| BLK | |||
| BMPR1A (ALK3) | |||
| BMPR1B (ALK6) | |||
| BMPR2 | |||
| BMX | |||
| BRAF | |||
| BRAF V599E | |||
| BRSK1 (SAD1) | |||
| BRSK2 | |||
| BTK | |||
| CAMK1 (CaMK1) | |||
| CAMK1D (CaMKI delta) | |||
| CAMK1G (CaMKI gamma) | |||
| CAMK2A (CaMKII alpha) | |||
| CAMK2B (CaMKII beta) | |||
| CAMK2D (CaMKII delta) | |||
| CAMK2G (CaMKII gamma) | |||
| CAMK4 (CaMKIV) | |||
| CAMKK1 (CAMKKA) | |||
| CAMKK2 (CaMKK beta) | |||
| CASK | |||
| CDC42 BPA (MRCKA) | |||
| CDC42 BPB (MRCKB) | |||
| CDC42 BPG (MRCKG) | |||
| CDC7/DBF4 | |||
| CDK1/cyclin B | |||
| CDK11 (Inactive) | |||
| CDK11/cyclin C | |||
| CDK13/cyclin K | |||
| CDK14 (PFTK1)/cyclin Y | |||
| CDK16 (PCTK1)/cyclin Y | |||
| CDK17/cyclin Y | |||
| CDK18/cyclin Y | |||
| CDK2/cyclin A | |||
| CDK2/cyclin A1 | |||
| CDK2/cyclin E1 | |||
| CDK2/cyclin O | |||
| CDK3/cyclin E1 | |||
| CDK4/cyclin D1 | |||
| CDK4/cyclin D3 | |||
| CDK5 (Inactive) | |||
| CDK5/p25 | |||
| CDK5/p35 | |||
| CDKL5 | |||
| CDK6/cyclin D1 | |||
| CDK7/cyclin H/MNAT1 | |||
| CDK8/cyclin C | |||
| CDK9 (Inactive) | |||
| CDK9/cyclin K | |||
| CDK9/cyclin T1 | |||
| CHEK1 (CHK1) | |||
| CHEK2 (CHK2) | |||
| CHUK (IKK alpha) | |||
| CLK1 | |||
| CLK2 | |||
| CLK3 | |||
| CLK4 | |||
| CSF1R (FMS) | |||
| CSK | |||
| CSNK1A1 (CK1 alpha 1) | |||
| CSNK1A1L | |||
| CSNK1D (CK1 delta) | |||
| CSNK1E (CK1 epsilon) | |||
| CSNK1E (CK1 epsilon) R178C | |||
| CSNK1G1 (CK1 gamma 1) | |||
| CSNK1G2 (CK1 gamma 2) | |||
| CSNK1G3 (CK1 gamma 3) | |||
| CSNK2A1 (CK2 alpha 1) | |||
| CSNK2A2 (CK2 alpha 2) | |||
| DAPK1 | |||
| DAPK2 | |||
| DAPK3 (ZIPK) | |||
| DCAMKL1 (DCLK1) | |||
| DCAMKL2 (DCK2) | |||
| DDR1 | |||
| DDR2 | |||
| DDR2 N456S | |||
| DDR2 T654M | |||
| DMPK | |||
| DNA-PK | |||
| DYRK1A | |||
| DYRK1B | |||
| DYRK2 | |||
| DYRK3 | |||
| DYRK4 | |||
| EEF2K | |||
| EGFR (ErbB1) | |||
| EGFR (ErbB1) C797S | |||
| EGFR (ErbB1) d747-749 A750P | |||
| EGFR (ErbB1) G719C | |||
| EGFR (ErbB1) G719S | |||
| EGFR (ErbB1) L858R | |||
| EGFR (ErbB1) L861Q | |||
| EGFR (ErbB1) T790M | |||
| EGFR (ErbB1) T790M C797S L858R | |||
| EGFR (ErbB1) T790M L858R | |||
| EGFR d746-750 | |||
| EIF2AK2 | |||
| EPHA1 | |||
| EPHA2 | |||
| EPHA3 | |||
| EPHA4 | |||
| EPHA5 | |||
| EPHA6 | |||
| EPHA7 | |||
| EPHA8 | |||
| EPHB1 | |||
| EPHB2 | |||
| EPHB3 | |||
| EPHB4 | |||
| ERBB2 (HER2) | |||
| ERBB4 (HER4) | |||
| ERN1 | |||
| ERN2 | |||
| FER | |||
| FES (FPS) | |||
| FGFR1 | |||
| FGFR1 V561M | |||
| FGFR2 | |||
| FGFR2 N549H | |||
| FGFR3 | |||
| FGFR3 G697C | |||
| FGFR3 K650E | |||
| FGFR3 K650M | |||
| FGFR3 V555M | |||
| FGFR4 | |||
| FGR | |||
| FLT4 (VEGFR3) | |||
| FLT1 (VEGFR1) | |||
| FLT3 | |||
| FLT3 D835Y | |||
| FLT3 ITD | |||
| FRAP1 (mTOR) | |||
| FRK (PTK5) | |||
| FYN | |||
| FYN A | |||
| GAK | |||
| GRK1 | |||
| GRK4 | |||
| GRK5 | |||
| GRK6 | |||
| GRK7 | |||
| GSG2 (Haspin) | |||
| GSK3A (GSK3 alpha) | |||
| GSK3B (GSK3 beta) | |||
| HCK | |||
| HIPK1 (Myak) | |||
| HIPK2 | |||
| HIPK3 (YAK1) | |||
| HIPK4 | |||
| HUNK | |||
| ICK | |||
| IGF1R | |||
| IKBKB (IKK beta) | |||
| IKBKE (IKK epsilon) | |||
| INSR | |||
| INSRR (IRR) | |||
| IRAK1 | |||
| IRAK3 | |||
| IRAK4 | |||
| ITK | |||
| JAK1 | |||
| JAK2 | |||
| JAK2 JH1 JH2 | |||
| JAK2 JH1 JH2 V617F | |||
| JAK3 | |||
| KDR (VEGFR2) | |||
| KIT | |||
| KIT A829P | |||
| KIT D816H | |||
| KIT D816V | |||
| KIT D820E | |||
| KIT N822K | |||
| KIT T670E | |||
| KIT T670I | |||
| KIT V559D | |||
| KIT V559D T670I | |||
| KIT V559D V654A | |||
| KIT V560G | |||
| KIT V654A | |||
| KIT Y823D | |||
| KSR2 | |||
| LATS1 | |||
| LATS2 | |||
| LCK | |||
| LIMK1 | |||
| LIMK2 | |||
| LRRK2 | |||
| LRRK2 FL | |||
| LRRK2 G2019S | |||
| LRRK2 G2019S FL | |||
| LRRK2 I2020T | |||
| LRRK2 R1441C | |||
| LTK (TYK1) | |||
| LYN A | |||
| LYN B | |||
| MAP2K1 (MEK1 ) | |||
| MAP2K1 (MEK1) S218D S222D | |||
| MAP2K2 (MEK2) | |||
| MAP2K4 (MEK4) | |||
| MAP2K5 (MEK5) | |||
| MAP2K6 (MKK6) | |||
| MAP2K6 (MKK6) S207E T211E | |||
| MAP3K10 (MLK2) | |||
| MAP3K11 (MLK3) | |||
| MAP3K14 (NIK) | |||
| MAP3K19 (YSK4) | |||
| MAP3K2 (MEKK2) | |||
| MAP3K3 (MEKK3) | |||
| MAP3K5 (ASK1) | |||
| MAPK7 (ERK5) | |||
| MAP3K7/MAP3K7IP1 (TAK1-TAB1) | |||
| MAP3K8 (COT) | |||
| MAP3K9 (MLK1) | |||
| MAP4K1 (HPK1) | |||
| MAP4K2 (GCK) | |||
| MAP4K3 (GLK) | |||
| MAP4K4 (HGK) | |||
| MAP4K5 (KHS1) | |||
| MAPK1 (ERK2) | |||
| MAPK10 (JNK3) | |||
| MAPK11 (p38 beta) | |||
| MAPK12 (p38 gamma) | |||
| MAPK13 (p38 delta) | |||
| MAPK14 (p38 alpha) | |||
| MAPK14 (p38 alpha) Direct | |||
| MAPK15 (ERK7) | |||
| MAPK3 (ERK1) | |||
| MAPK8 (JNK1 ) | |||
| MAPK9 (JNK2) | |||
| MAPKAPK2 | |||
| MAPKAPK3 | |||
| MAPKAPK5 (PRAK) | |||
| MARK1 (MARK) | |||
| MARK2 | |||
| MARK3 | |||
| MARK4 | |||
| MASTL | |||
| MATK (HYL) | |||
| MELK | |||
| MERTK (cMER) | |||
| MERTK (cMER) A708S | |||
| MET (cMet) | |||
| MET (cMET) Y1235D | |||
| MET D1228H | |||
| MET M1250T | |||
| MINK1 | |||
| MKNK1 (MNK1) | |||
| MKNK2 (MNK2) | |||
| MLCK (MLCK2) | |||
| MLK4 | |||
| MST1R (RON) | |||
| MST4 | |||
| MUSK | |||
| MYLK (MLCK) | |||
| MYLK2 (skMLCK) | |||
| MYLK4 | |||
| MYO3A (MYO3 alpha) | |||
| MYO3B (MYO3 beta) | |||
| NEK1 | |||
| NEK2 | |||
| NEK4 | |||
| NEK6 | |||
| NEK7 | |||
| NEK8 | |||
| NEK9 | |||
| NIM1K | |||
| NLK | |||
| NTRK1 (TRKA) | |||
| NTRK2 (TRKB) | |||
| NTRK3 (TRKC) | |||
| NUAK1 (ARK5) | |||
| NUAK2 | |||
| PAK1 | |||
| PAK2 (PAK65) | |||
| PAK3 | |||
| PAK4 | |||
| PAK6 | |||
| PAK7 (KIAA1264) | |||
| PASK | |||
| PDGFRA (PDGFR alpha) | |||
| PDGFRA D842V | |||
| PDGFRA T674I | |||
| PDGFRA V561D | |||
| PDGFRB (PDGFR beta) | |||
| PDK1 | |||
| PDK1 Direct | |||
| PEAK1 | |||
| PHKG1 | |||
| PHKG2 | |||
| PI4K2A (PI4K2 alpha) | |||
| PI4K2B (PI4K2 beta) | |||
| PI4KA | |||
| PI4KB (PI4K beta) | |||
| PIK3C2A (PI3K-C2 alpha) | |||
| PIK3C2B (PI3K-C2 beta) | |||
| PIK3C2G (PI3K-C2 gamma) | |||
| PIK3C3 (hVPS34) | |||
| PIK3CA E542K/PIK3R1 (p110 alpha E542K/p85 alpha) | |||
| PIK3CA E545K/PIK3R1 (p110 alpha E545K/p85 alpha) | |||
| PIK3CA/PIK3R1 (p110 alpha/p85 alpha) | |||
| PIK3CA/PIK3R3 (p110 alpha /p55 gamma) | |||
| PIK3CB/PIK3R1 (p110 beta/p85 alpha) | |||
| PIK3CB/PIK3R2 (p110 beta/p85 beta) | |||
| PIK3CD/PIK3R1 (p110 delta/p85 alpha) | |||
| PIK3CG (p110 gamma) | |||
| PIM1 | |||
| PIM2 | |||
| PIM3 | |||
| PIP4K2A | |||
| PIP5K1A | |||
| PIP5K1B | |||
| PIP5K1C | |||
| PKN1 (PRK1) | |||
| PKN2 | |||
| PLK1 | |||
| PLK2 | |||
| PLK3 | |||
| PLK4 | |||
| PKMYT1 | |||
| PRKACA (PKA) | |||
| PRKACB (PRKAC beta) | |||
| PRKACG (PRKAC gamma) | |||
| PRKCA (PKC alpha) | |||
| PRKCB1 (PKC beta I) | |||
| PRKCB2 (PKC beta II) | |||
| PRKCD (PKC delta) | |||
| PRKCE (PKC epsilon) | |||
| PRKCG (PKC gamma) | |||
| PRKCH (PKC eta) | |||
| PRKCI (PKC iota) | |||
| PRKCN (PKD3) | |||
| PRKCQ (PKC theta) | |||
| PRKCZ (PKC zeta) | |||
| PRKD1 (PKC mu) | |||
| PRKD2 (PKD2) | |||
| PRKG1 | |||
| PRKG2 (PKG2) | |||
| PRKX | |||
| PTK2 (FAK) | |||
| PTK2B (FAK2) | |||
| PTK6 (Brk) | |||
| RAF1 (cRAF) Y340D Y341D | |||
| RET | |||
| RET A883F | |||
| RET G691S | |||
| RET M918T | |||
| RET S891A | |||
| RET V804E | |||
| RET V804L | |||
| RET V804M | |||
| RET Y791F | |||
| RIPK2 | |||
| RIPK3 | |||
| ROCK1 | |||
| ROCK2 | |||
| ROS1 | |||
| RPS6KA1 (RSK1) | |||
| RPS6KA2 (RSK3) | |||
| RPS6KA3 (RSK2) | |||
| RPS6KA4 (MSK2) | |||
| RPS6KA5 (MSK1) | |||
| RPS6KA6 (RSK4) | |||
| RPS6KB1 (p70S6K) | |||
| RPS6KB2 (p70S6Kb) | |||
| SBK1 | |||
| SGK (SGK1) | |||
| SGK2 | |||
| SGKL (SGK3) | |||
| SIK1 | |||
| SIK3 | |||
| SLK | |||
| SNF1LK2 | |||
| SPHK1 | |||
| SPHK2 | |||
| SRC | |||
| SRC N1 | |||
| SRMS (Srm) | |||
| SRPK1 | |||
| SRPK2 | |||
| STK16 (PKL12) | |||
| STK17A (DRAK1) | |||
| STK17B (DRAK2) | |||
| STK22B (TSSK2) | |||
| STK22D (TSSK1) | |||
| STK23 (MSSK1) | |||
| STK24 (MST3) | |||
| STK25 (YSK1) | |||
| STK3 (MST2 ) | |||
| STK32B (YANK2) | |||
| STK32C (YANK3) | |||
| STK33 | |||
| STK38 (NDR) | |||
| STK38L (NDR2) | |||
| STK39 (STLK3) | |||
| STK4 (MST1) | |||
| SYK | |||
| TAOK1 | |||
| TAOK2 (TAO1) | |||
| TAOK3 (JIK) | |||
| TBK1 | |||
| TEC | |||
| TEK (TIE2) | |||
| TEK (TIE2) R849W | |||
| TEK (TIE2) Y1108F | |||
| TEK (TIE2) Y897S | |||
| TESK1 | |||
| TGFBR1 (ALK5) | |||
| TGFBR2 | |||
| TLK1 | |||
| TLK2 | |||
| TNIK | |||
| TNK1 | |||
| TNK2 (ACK) | |||
| TTK | |||
| TXK | |||
| TYK2 | |||
| TYRO3 (RSE) | |||
| ULK1 | |||
| ULK2 | |||
| ULK3 | |||
| VRK2 | |||
| WEE1 | |||
| WNK1 | |||
| WNK2 | |||
| WNK3 | |||
| YES1 | |||
| ZAK | |||
| ZAP70 | |||
Kinase biology tools
With the broadest collections of assays, high-throughput screening and profiling services, and access to customized assays and tools designed to meet your specifications, your lab can choose the right kinase biology tools and services for your exact stage of research.
Project options
Customize your kinase profiling project to get the right data for your research.
Standard service options include:
- Targets – >485 available biochemical assays
- Mode – Single point concentrations and IC50 and/or EC50 determinations
- Choice of ATP concentration – 10µM, 100µM, and Km [app] ATP (activity assays only)
For the kinases that are available in our activity assays, comprehensive titrations are performed against our panel of available substrates. In addition, ATP titrations are performed for each of these kinases to determine the Km[app] ATP for each target. As a result, you can choose to have your compound run at, above, or below the Km[app] ATP for each kinase within the panel that utilizes an activity assay. This flexibility allows you to identify specific types of inhibitors with various mechanisms of action.
To discuss your kinase profiling project requirements, send us an inquiry
Personalized support
From project beginning to end, you can rely on our Drug Discovery Services project management team to provide frequent project communication via a single point of contact.
Watch this two-minute video to see how our project managers and technical specialists create an exceptional experience for our customers. Submit order
Technology overview
Currently, two different assay platforms are available for profiling – activity and binding. The Z′-LYTE and Adapta kinase activity assays are used most extensively for profiling and a smaller subset of kinases may be profiled using our LanthaScreen Eu Kinase Binding Assays.
Overview of available formats
| Z′-LYTE | Technology Overview | Protocol and Assay Conditions |
| Adapta | Technology Overview | Protocol and Assay Conditions |
| LanthaScreen Eu Kinase Binding Assay | Technology Overview | Protocol and Assay Conditions |
A stringent validation process ensures the highest quality data possible with each data point performed in duplicate. Strict quality control protocols ensure that any assay results not meeting set specifications will be automatically repeated, this includes a control inhibitor titration (IC50) for each kinase on every plate.
To discuss your kinase profiling project requirements, send us an inquiry.
Broad assay panel
| Kinase | Activity assays | Binding assay | |
|---|---|---|---|
| Z′-LYTE | Adapta | LanthaScreen | |
| AAK1 | |||
| ABL1 | |||
| ABL1 E255K | |||
| ABL1 F317I | |||
| ABL1 F317L | |||
| ABL1 G250E | |||
| ABL1 H396P | |||
| ABL1 M351T | |||
| ABL1 Q252H | |||
| ABL1 T315I | |||
| ABL1 Y253F | |||
| ABL2 (Arg) | |||
| ACVR1 (ALK2) | |||
| ACVR1 (ALK2) R206H | |||
| ACVR1B (ALK4) | |||
| ACVR2A | |||
| ACVR2B | |||
| ACVRL1 | |||
| ADCK3 | |||
| ADRBK1 (GRK2) | |||
| ADRBK2 (GRK3) | |||
| AKT1 (PKB alpha) | |||
| AKT2 (PKB beta) | |||
| AKT3 (PKB gamma) | |||
| ALK | |||
| ALK C1156Y | |||
| ALK F1174L | |||
| ALK L1196M | |||
| ALK R1275Q | |||
| ALK T1151_L1152insT | |||
| AMPK (A1/B1/G2) | |||
| AMPK (A1/B1/G3) | |||
| AMPK (A1/B2/G1) | |||
| AMPK (A1/B2/G2) | |||
| AMPK (A1/B2/G3) | |||
| AMPK (A2/B1/G2) | |||
| AMPK (A2/B1/G3) | |||
| AMPK (A2/B2/G1) | |||
| AMPK (A2/B2/G2) | |||
| AMPK (A2/B2/G3) | |||
| AMPK A1/B1/G1 | |||
| AMPK A2/B1/G1 | |||
| AURKA (Aurora A) | |||
| AURKB (Aurora B) | |||
| AURKC (Aurora C) | |||
| AXL | |||
| AXL R499C | |||
| BLK | |||
| BMPR1A (ALK3) | |||
| BMPR1B (ALK6) | |||
| BMPR2 | |||
| BMX | |||
| BRAF | |||
| BRAF V599E | |||
| BRSK1 (SAD1) | |||
| BRSK2 | |||
| BTK | |||
| CAMK1 (CaMK1) | |||
| CAMK1D (CaMKI delta) | |||
| CAMK1G (CaMKI gamma) | |||
| CAMK2A (CaMKII alpha) | |||
| CAMK2B (CaMKII beta) | |||
| CAMK2D (CaMKII delta) | |||
| CAMK2G (CaMKII gamma) | |||
| CAMK4 (CaMKIV) | |||
| CAMKK1 (CAMKKA) | |||
| CAMKK2 (CaMKK beta) | |||
| CASK | |||
| CDC42 BPA (MRCKA) | |||
| CDC42 BPB (MRCKB) | |||
| CDC42 BPG (MRCKG) | |||
| CDC7/DBF4 | |||
| CDK1/cyclin B | |||
| CDK11 (Inactive) | |||
| CDK11/cyclin C | |||
| CDK13/cyclin K | |||
| CDK14 (PFTK1)/cyclin Y | |||
| CDK16 (PCTK1)/cyclin Y | |||
| CDK17/cyclin Y | |||
| CDK18/cyclin Y | |||
| CDK2/cyclin A | |||
| CDK2/cyclin A1 | |||
| CDK2/cyclin E1 | |||
| CDK2/cyclin O | |||
| CDK3/cyclin E1 | |||
| CDK4/cyclin D1 | |||
| CDK4/cyclin D3 | |||
| CDK5 (Inactive) | |||
| CDK5/p25 | |||
| CDK5/p35 | |||
| CDKL5 | |||
| CDK6/cyclin D1 | |||
| CDK7/cyclin H/MNAT1 | |||
| CDK8/cyclin C | |||
| CDK9 (Inactive) | |||
| CDK9/cyclin K | |||
| CDK9/cyclin T1 | |||
| CHEK1 (CHK1) | |||
| CHEK2 (CHK2) | |||
| CHUK (IKK alpha) | |||
| CLK1 | |||
| CLK2 | |||
| CLK3 | |||
| CLK4 | |||
| CSF1R (FMS) | |||
| CSK | |||
| CSNK1A1 (CK1 alpha 1) | |||
| CSNK1A1L | |||
| CSNK1D (CK1 delta) | |||
| CSNK1E (CK1 epsilon) | |||
| CSNK1E (CK1 epsilon) R178C | |||
| CSNK1G1 (CK1 gamma 1) | |||
| CSNK1G2 (CK1 gamma 2) | |||
| CSNK1G3 (CK1 gamma 3) | |||
| CSNK2A1 (CK2 alpha 1) | |||
| CSNK2A2 (CK2 alpha 2) | |||
| DAPK1 | |||
| DAPK2 | |||
| DAPK3 (ZIPK) | |||
| DCAMKL1 (DCLK1) | |||
| DCAMKL2 (DCK2) | |||
| DDR1 | |||
| DDR2 | |||
| DDR2 N456S | |||
| DDR2 T654M | |||
| DMPK | |||
| DNA-PK | |||
| DYRK1A | |||
| DYRK1B | |||
| DYRK2 | |||
| DYRK3 | |||
| DYRK4 | |||
| EEF2K | |||
| EGFR (ErbB1) | |||
| EGFR (ErbB1) C797S | |||
| EGFR (ErbB1) d747-749 A750P | |||
| EGFR (ErbB1) G719C | |||
| EGFR (ErbB1) G719S | |||
| EGFR (ErbB1) L858R | |||
| EGFR (ErbB1) L861Q | |||
| EGFR (ErbB1) T790M | |||
| EGFR (ErbB1) T790M C797S L858R | |||
| EGFR (ErbB1) T790M L858R | |||
| EGFR d746-750 | |||
| EIF2AK2 | |||
| EPHA1 | |||
| EPHA2 | |||
| EPHA3 | |||
| EPHA4 | |||
| EPHA5 | |||
| EPHA6 | |||
| EPHA7 | |||
| EPHA8 | |||
| EPHB1 | |||
| EPHB2 | |||
| EPHB3 | |||
| EPHB4 | |||
| ERBB2 (HER2) | |||
| ERBB4 (HER4) | |||
| ERN1 | |||
| ERN2 | |||
| FER | |||
| FES (FPS) | |||
| FGFR1 | |||
| FGFR1 V561M | |||
| FGFR2 | |||
| FGFR2 N549H | |||
| FGFR3 | |||
| FGFR3 G697C | |||
| FGFR3 K650E | |||
| FGFR3 K650M | |||
| FGFR3 V555M | |||
| FGFR4 | |||
| FGR | |||
| FLT4 (VEGFR3) | |||
| FLT1 (VEGFR1) | |||
| FLT3 | |||
| FLT3 D835Y | |||
| FLT3 ITD | |||
| FRAP1 (mTOR) | |||
| FRK (PTK5) | |||
| FYN | |||
| FYN A | |||
| GAK | |||
| GRK1 | |||
| GRK4 | |||
| GRK5 | |||
| GRK6 | |||
| GRK7 | |||
| GSG2 (Haspin) | |||
| GSK3A (GSK3 alpha) | |||
| GSK3B (GSK3 beta) | |||
| HCK | |||
| HIPK1 (Myak) | |||
| HIPK2 | |||
| HIPK3 (YAK1) | |||
| HIPK4 | |||
| HUNK | |||
| ICK | |||
| IGF1R | |||
| IKBKB (IKK beta) | |||
| IKBKE (IKK epsilon) | |||
| INSR | |||
| INSRR (IRR) | |||
| IRAK1 | |||
| IRAK3 | |||
| IRAK4 | |||
| ITK | |||
| JAK1 | |||
| JAK2 | |||
| JAK2 JH1 JH2 | |||
| JAK2 JH1 JH2 V617F | |||
| JAK3 | |||
| KDR (VEGFR2) | |||
| KIT | |||
| KIT A829P | |||
| KIT D816H | |||
| KIT D816V | |||
| KIT D820E | |||
| KIT N822K | |||
| KIT T670E | |||
| KIT T670I | |||
| KIT V559D | |||
| KIT V559D T670I | |||
| KIT V559D V654A | |||
| KIT V560G | |||
| KIT V654A | |||
| KIT Y823D | |||
| KSR2 | |||
| LATS1 | |||
| LATS2 | |||
| LCK | |||
| LIMK1 | |||
| LIMK2 | |||
| LRRK2 | |||
| LRRK2 FL | |||
| LRRK2 G2019S | |||
| LRRK2 G2019S FL | |||
| LRRK2 I2020T | |||
| LRRK2 R1441C | |||
| LTK (TYK1) | |||
| LYN A | |||
| LYN B | |||
| MAP2K1 (MEK1 ) | |||
| MAP2K1 (MEK1) S218D S222D | |||
| MAP2K2 (MEK2) | |||
| MAP2K4 (MEK4) | |||
| MAP2K5 (MEK5) | |||
| MAP2K6 (MKK6) | |||
| MAP2K6 (MKK6) S207E T211E | |||
| MAP3K10 (MLK2) | |||
| MAP3K11 (MLK3) | |||
| MAP3K14 (NIK) | |||
| MAP3K19 (YSK4) | |||
| MAP3K2 (MEKK2) | |||
| MAP3K3 (MEKK3) | |||
| MAP3K5 (ASK1) | |||
| MAPK7 (ERK5) | |||
| MAP3K7/MAP3K7IP1 (TAK1-TAB1) | |||
| MAP3K8 (COT) | |||
| MAP3K9 (MLK1) | |||
| MAP4K1 (HPK1) | |||
| MAP4K2 (GCK) | |||
| MAP4K3 (GLK) | |||
| MAP4K4 (HGK) | |||
| MAP4K5 (KHS1) | |||
| MAPK1 (ERK2) | |||
| MAPK10 (JNK3) | |||
| MAPK11 (p38 beta) | |||
| MAPK12 (p38 gamma) | |||
| MAPK13 (p38 delta) | |||
| MAPK14 (p38 alpha) | |||
| MAPK14 (p38 alpha) Direct | |||
| MAPK15 (ERK7) | |||
| MAPK3 (ERK1) | |||
| MAPK8 (JNK1 ) | |||
| MAPK9 (JNK2) | |||
| MAPKAPK2 | |||
| MAPKAPK3 | |||
| MAPKAPK5 (PRAK) | |||
| MARK1 (MARK) | |||
| MARK2 | |||
| MARK3 | |||
| MARK4 | |||
| MASTL | |||
| MATK (HYL) | |||
| MELK | |||
| MERTK (cMER) | |||
| MERTK (cMER) A708S | |||
| MET (cMet) | |||
| MET (cMET) Y1235D | |||
| MET D1228H | |||
| MET M1250T | |||
| MINK1 | |||
| MKNK1 (MNK1) | |||
| MKNK2 (MNK2) | |||
| MLCK (MLCK2) | |||
| MLK4 | |||
| MST1R (RON) | |||
| MST4 | |||
| MUSK | |||
| MYLK (MLCK) | |||
| MYLK2 (skMLCK) | |||
| MYLK4 | |||
| MYO3A (MYO3 alpha) | |||
| MYO3B (MYO3 beta) | |||
| NEK1 | |||
| NEK2 | |||
| NEK4 | |||
| NEK6 | |||
| NEK7 | |||
| NEK8 | |||
| NEK9 | |||
| NIM1K | |||
| NLK | |||
| NTRK1 (TRKA) | |||
| NTRK2 (TRKB) | |||
| NTRK3 (TRKC) | |||
| NUAK1 (ARK5) | |||
| NUAK2 | |||
| PAK1 | |||
| PAK2 (PAK65) | |||
| PAK3 | |||
| PAK4 | |||
| PAK6 | |||
| PAK7 (KIAA1264) | |||
| PASK | |||
| PDGFRA (PDGFR alpha) | |||
| PDGFRA D842V | |||
| PDGFRA T674I | |||
| PDGFRA V561D | |||
| PDGFRB (PDGFR beta) | |||
| PDK1 | |||
| PDK1 Direct | |||
| PEAK1 | |||
| PHKG1 | |||
| PHKG2 | |||
| PI4K2A (PI4K2 alpha) | |||
| PI4K2B (PI4K2 beta) | |||
| PI4KA | |||
| PI4KB (PI4K beta) | |||
| PIK3C2A (PI3K-C2 alpha) | |||
| PIK3C2B (PI3K-C2 beta) | |||
| PIK3C2G (PI3K-C2 gamma) | |||
| PIK3C3 (hVPS34) | |||
| PIK3CA E542K/PIK3R1 (p110 alpha E542K/p85 alpha) | |||
| PIK3CA E545K/PIK3R1 (p110 alpha E545K/p85 alpha) | |||
| PIK3CA/PIK3R1 (p110 alpha/p85 alpha) | |||
| PIK3CA/PIK3R3 (p110 alpha /p55 gamma) | |||
| PIK3CB/PIK3R1 (p110 beta/p85 alpha) | |||
| PIK3CB/PIK3R2 (p110 beta/p85 beta) | |||
| PIK3CD/PIK3R1 (p110 delta/p85 alpha) | |||
| PIK3CG (p110 gamma) | |||
| PIM1 | |||
| PIM2 | |||
| PIM3 | |||
| PIP4K2A | |||
| PIP5K1A | |||
| PIP5K1B | |||
| PIP5K1C | |||
| PKN1 (PRK1) | |||
| PKN2 | |||
| PLK1 | |||
| PLK2 | |||
| PLK3 | |||
| PLK4 | |||
| PKMYT1 | |||
| PRKACA (PKA) | |||
| PRKACB (PRKAC beta) | |||
| PRKACG (PRKAC gamma) | |||
| PRKCA (PKC alpha) | |||
| PRKCB1 (PKC beta I) | |||
| PRKCB2 (PKC beta II) | |||
| PRKCD (PKC delta) | |||
| PRKCE (PKC epsilon) | |||
| PRKCG (PKC gamma) | |||
| PRKCH (PKC eta) | |||
| PRKCI (PKC iota) | |||
| PRKCN (PKD3) | |||
| PRKCQ (PKC theta) | |||
| PRKCZ (PKC zeta) | |||
| PRKD1 (PKC mu) | |||
| PRKD2 (PKD2) | |||
| PRKG1 | |||
| PRKG2 (PKG2) | |||
| PRKX | |||
| PTK2 (FAK) | |||
| PTK2B (FAK2) | |||
| PTK6 (Brk) | |||
| RAF1 (cRAF) Y340D Y341D | |||
| RET | |||
| RET A883F | |||
| RET G691S | |||
| RET M918T | |||
| RET S891A | |||
| RET V804E | |||
| RET V804L | |||
| RET V804M | |||
| RET Y791F | |||
| RIPK2 | |||
| RIPK3 | |||
| ROCK1 | |||
| ROCK2 | |||
| ROS1 | |||
| RPS6KA1 (RSK1) | |||
| RPS6KA2 (RSK3) | |||
| RPS6KA3 (RSK2) | |||
| RPS6KA4 (MSK2) | |||
| RPS6KA5 (MSK1) | |||
| RPS6KA6 (RSK4) | |||
| RPS6KB1 (p70S6K) | |||
| RPS6KB2 (p70S6Kb) | |||
| SBK1 | |||
| SGK (SGK1) | |||
| SGK2 | |||
| SGKL (SGK3) | |||
| SIK1 | |||
| SIK3 | |||
| SLK | |||
| SNF1LK2 | |||
| SPHK1 | |||
| SPHK2 | |||
| SRC | |||
| SRC N1 | |||
| SRMS (Srm) | |||
| SRPK1 | |||
| SRPK2 | |||
| STK16 (PKL12) | |||
| STK17A (DRAK1) | |||
| STK17B (DRAK2) | |||
| STK22B (TSSK2) | |||
| STK22D (TSSK1) | |||
| STK23 (MSSK1) | |||
| STK24 (MST3) | |||
| STK25 (YSK1) | |||
| STK3 (MST2 ) | |||
| STK32B (YANK2) | |||
| STK32C (YANK3) | |||
| STK33 | |||
| STK38 (NDR) | |||
| STK38L (NDR2) | |||
| STK39 (STLK3) | |||
| STK4 (MST1) | |||
| SYK | |||
| TAOK1 | |||
| TAOK2 (TAO1) | |||
| TAOK3 (JIK) | |||
| TBK1 | |||
| TEC | |||
| TEK (TIE2) | |||
| TEK (TIE2) R849W | |||
| TEK (TIE2) Y1108F | |||
| TEK (TIE2) Y897S | |||
| TESK1 | |||
| TGFBR1 (ALK5) | |||
| TGFBR2 | |||
| TLK1 | |||
| TLK2 | |||
| TNIK | |||
| TNK1 | |||
| TNK2 (ACK) | |||
| TTK | |||
| TXK | |||
| TYK2 | |||
| TYRO3 (RSE) | |||
| ULK1 | |||
| ULK2 | |||
| ULK3 | |||
| VRK2 | |||
| WEE1 | |||
| WNK1 | |||
| WNK2 | |||
| WNK3 | |||
| YES1 | |||
| ZAK | |||
| ZAP70 | |||
Kinase biology tools
With the broadest collections of assays, high-throughput screening and profiling services, and access to customized assays and tools designed to meet your specifications, your lab can choose the right kinase biology tools and services for your exact stage of research.
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