Oncology Research with Laser Capture Microdissection (LCM)

The heterogeneous nature of tumor biopsies can make it difficult to generate useful genomic data from whole tissue samples. Laser capture microdissection (LCM) is a powerful technique that has become instrumental to researchers interested in comparing the molecular profiles of tumor tissue to surrounding non-tumor cells, thereby unlocking hidden molecular signatures in individual patient tumor samples and leading the way for tailored treatment and personalized medicine. The gentle IR laser of the Arcturus LCM systems preserves tissue morphology and genetic content of captured and neighboring cells, providing researchers with an effective tool to easily verify captured material while simultaneously preserving biomolecule integrity.