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Ion AmpliSeq On-Demand Panels for Targeted Sequencing
Gene panels on demand, how and when you want them
Ion AmpliSeq On-Demand panels bring practical pack sizes and a optimized gene catalog to custom next-generation sequencing (NGS) panels, so you can iterate panel design for human disease research with efficiency and convenience.
New additions to our portfolio give you more selection and pack sizes, allowing you to build custom panels from over 5,000 pretested genes that are most relevant in the research of inherited diseases—these include hereditary cancer, primary immunodeficiency, hearing loss, muscular dystrophy and many more. Order the exact quantity you need by selecting from 8-, 24-, 32- and 96-reaction sizes.
When are my genes available?
Enter your gene(s) of interest in the gene search tool to see if they have been added to the Ion AmpliSeq On-Demand catalog.
Our catalog of optimized genes continues to expand to include more areas of disease research, so be sure to come back and check if you don’t see your genes in the catalog now. Please note that currently the On-Demand catalog includes genes for germline analysis only.
If you don't see your gene of interest, you can still order an On-Demand panel and we can spike-in additional genes. (Watch a short video on how to create a spike-in panel.)
What are the pack sizes?
Ion AmpliSeq On-Demand panels are available in 8-, 24-, 32- and 96-reaction packs to fit a variety of experimental needs, whether you’re running Ion Chef System automation or manual library and template preparation.
Smaller pack sizes help keep up-front costs down so you can more efficiently design, run, and re-design panels. Simply select your preferred library preparation workflow during checkout after you have designed a panel.
Ion AmpliSeq On-Demand Panel – Product configuration | ||||
| Library Workflow | Pack size(reactions) | Number of genes in panel | ||
| 1 to 50 | 51 to 300 | 301 to 500 NEW | ||
| Manual | 24 | ✓ | ✓ | ✓ |
| 96 | ✓ | ✓ | ✓ | |
| Ion Chef System ready | 8 | ✓ | ✓ | ✓ |
| 32 | ✓ | ✓ | ✓ | |
Select genes by starting with your disease research area
Start with your disease research area of interest in Ion AmpliSeq Designer and easily configure your own panel. Genes are organized by their degree of disease association as informed by public databases such as the Medical Subject Headings (MeSH) database—so you spend less time on panel development and more time on delivering results.
View wet-lab data on gene uniformity during the design stage to be assured of the quality of the expected data, even before running your first experiment.
Ion AmpliSeq On-Demand panels cover broad research areas for germline analysis, including:
- American College of Medical Genetics and Genomics (ACMG) recommended genes for reporting incidental findings
- Newborn screening research
- Inherited cancers research
- Common adult and childhood disorders (e.g., Noonan Syndrome) research
- Other commonly studied genes associated with clinical disease research
Click image to enlarge
Click image to enlarge
Getting started with Ion AmpliSeq On-Demand panels
Start by watching the following quick demo videos. Find more videos like this to help you get started ›
Video: Don’t have a gene list? Select from our gene-disease catalog.
Learn how to easily select genes for your panel by browsing different disease research areas (~3 min)
Video: Want to add genes that are not currently in the gene-disease catalog?
Create an On-Demand panel design and we can spike-in additional genes (~3 min)
What is an Ion AmpliSeq panel?
Ion AmpliSeq panels consist of a pool of oligonucleotide primer pairs, each pair designed to amplify a specified genomic region. Each panel can be designed to interrogate all bases across a gene.
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For Research Use Only. Not for use in diagnostic procedures.