Oncomine Comprehensive Assays

Oncomine Comprehensive assays, based on Ion Ampliseq technology and enabled by the Ion Torrent sequencing platforms, provide:

• Relevant content based on evidence from Oncomine Knowledgebase, a proprietary genomic database curated over a decade and cited thousands of times for oncology research, and from collaboration with leading oncology research institutions and pharma companies
• Multiple biomarker type analysis including hotspot SNVs, indels, CNVs, and gene fusions across a range of cancer types
• Proven and reliable performance with high specificity, sensitivity, and reproducibility across different research laboratories, enabled by the robust design and enhanced manufacturing quality of reagents in our ISO13485-compliant facility, including enhanced QC
• Robust results from even those challenging FFPE tissue samples, including FNAs, with sample input as low as 10 ngs of DNA and RNA
• Efficient workflow on Ion Chef System plus Ion GeneStudio S5 or Ion Torrent Genexus system with high multiplexing flexibility and fast time to results
• Enhanced bioinformatics and reporting solutions developed for the Ion Torrent platforms and optimized Oncomine assays, including Oncomine Reporter, enabling contextual investigation of sample-specific variants to understand their relevance in the latest oncology research

Compare and contrast the Oncomine Comprehensive Assay Plus and the Oncomine Comprehensive Assay v3. Follow the links below to see performance data and learn more about each assay.

Oncomine Comprehensive assays are part of an end-to-end workflow that includes sample preparation on the Ion Chef System, scalable sequencing with the Ion GeneStudio S5 or Genexus Systems, and post-sequencing analysis on Ion Reporter Software with a results report provided by Oncomine Reporter.