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Organic Chemical Synthesis
Organic synthesis reagents are essential in synthetic chemistry, allowing transformations of building blocks into target molecules quickly, safely, and cleanly. Over 5,000 products are available from the combined Acros Organics and Alfa Aesar portfolios.
Our range of ligands includes 250 products such as Triphenylphosphine, sulfonic acid sodium salts, Ferrocene, 18-Crown-6, and Kryptofix® 222 from product categories including phosphine, Buchwald type, BINAP, NHC, and Josiphos ligands.
Also available are Phosphonium hexafluoroborates and tetrafluoroborates, offering air stable and safer alternatives to the pyrophoric trialkyl phosphines. Our wide selection of monodentate and bidentate ligands is offered in convenient pack sizes ideal for your synthetic chemistry research.
There are over 700 products specifically categorised as organic reagents in our portfolio. Subsets of products are taken from all aspects of organic chemistry, including reagents used for halogenation, oxidation, and reduction. Our products range in diversity from relatively simple molecules like acetic anhydride to complex molecules such as EDTA, all with specific functional reagent capabilities to facilitate transformations.
Where beneficial, products are available as pre-made solutions, e.g. Glutaraldehyde (both 50% and 25% aqueous solution), Sodium biphenyl in diethylene glycol diethyl ether, (Trimethylsilyl) diazomethane in hexanes, Sodium methoxide in methanol, and Borane-tetrahydrofuran complex in THF, alongside high purity products such as Imidazole, Phenol, Sodium borohydride, and N-Bromosuccinimide.
Organosilanes have varied uses in organic chemistry, from the most frequently employed protecting groups to intermediates in organic synthesis. Look out for the most commonly used products like Tetramethylsilane, tert-Butyldimethylchlorosilane, Triisopropylsilane, 3-Glycidoxypropyltrimethoxysilane, and N,O-Bis(trimethylsilyl) trifluoroacetamide amongst the complete Acros Organics and Alfa Aesar portfolios of organosilanes used in four of the most important applications:
- Silyl protecting and derivatisation reagents
- Organosilanes as reducing agents
- Silanes in cross-coupling chemistry
- Allylsilanes used to stabilize α-carbanions and β-carbocations
Organometallic reagents are widely used in organic synthesis. Typical applications include their use as strong bases, as nucleophiles, in metal exchange reactions, and as reducing agents. Examples of such reagents include n-Butyllithium, Diisobutylaluminium hydride, Hexamethylditin, Titanium(IV) n-butoxide, Methylmagnesium bromide, Octacarbonyldicobalt, and Sodium 1-heptanesulfonate monohydrate amongst the broad categories of Grignard reagents, organolithiums, organozincs, and lithium amide bases.
Many reagents do not fall easily into the five specific categories listed, such as Tetrabutylammonium hydroxide, Trifluoroacetic anhydride, Oxalyl chloride, Polyvinylsulfuric acid potassium salt, and Poly(propylene glycol). Over 450 'other reagent' products covering a wide range of applications are also available.
Our range of ligands includes 250 products such as Triphenylphosphine, sulfonic acid sodium salts, Ferrocene, 18-Crown-6, and Kryptofix® 222 from product categories including phosphine, Buchwald type, BINAP, NHC, and Josiphos ligands.
Also available are Phosphonium hexafluoroborates and tetrafluoroborates, offering air stable and safer alternatives to the pyrophoric trialkyl phosphines. Our wide selection of monodentate and bidentate ligands is offered in convenient pack sizes ideal for your synthetic chemistry research.
There are over 700 products specifically categorised as organic reagents in our portfolio. Subsets of products are taken from all aspects of organic chemistry, including reagents used for halogenation, oxidation, and reduction. Our products range in diversity from relatively simple molecules like acetic anhydride to complex molecules such as EDTA, all with specific functional reagent capabilities to facilitate transformations.
Where beneficial, products are available as pre-made solutions, e.g. Glutaraldehyde (both 50% and 25% aqueous solution), Sodium biphenyl in diethylene glycol diethyl ether, (Trimethylsilyl) diazomethane in hexanes, Sodium methoxide in methanol, and Borane-tetrahydrofuran complex in THF, alongside high purity products such as Imidazole, Phenol, Sodium borohydride, and N-Bromosuccinimide.
Organosilanes have varied uses in organic chemistry, from the most frequently employed protecting groups to intermediates in organic synthesis. Look out for the most commonly used products like Tetramethylsilane, tert-Butyldimethylchlorosilane, Triisopropylsilane, 3-Glycidoxypropyltrimethoxysilane, and N,O-Bis(trimethylsilyl) trifluoroacetamide amongst the complete Acros Organics and Alfa Aesar portfolios of organosilanes used in four of the most important applications:
- Silyl protecting and derivatisation reagents
- Organosilanes as reducing agents
- Silanes in cross-coupling chemistry
- Allylsilanes used to stabilize α-carbanions and β-carbocations
Organometallic reagents are widely used in organic synthesis. Typical applications include their use as strong bases, as nucleophiles, in metal exchange reactions, and as reducing agents. Examples of such reagents include n-Butyllithium, Diisobutylaluminium hydride, Hexamethylditin, Titanium(IV) n-butoxide, Methylmagnesium bromide, Octacarbonyldicobalt, and Sodium 1-heptanesulfonate monohydrate amongst the broad categories of Grignard reagents, organolithiums, organozincs, and lithium amide bases.
Many reagents do not fall easily into the five specific categories listed, such as Tetrabutylammonium hydroxide, Trifluoroacetic anhydride, Oxalyl chloride, Polyvinylsulfuric acid potassium salt, and Poly(propylene glycol). Over 450 'other reagent' products covering a wide range of applications are also available.
Acroseal packaging
When carrying out synthetic organic chemistry, exposing many solvents and reagents to air and moisture inhibits their ability to perform properly and can cause some, if not all, of the following issues:
- A failed synthesis
- Poor yield
- Greater number of by-products and/or impurities
- More challenging purification
Our AcroSeal packaging solution is innovative and simple as we endeavour to:
- Pack the product when it is as dry as possible
- Make it easy to keep it dry when transferring from the packaging into your dry system
- Ensure products stay dry between repeated use
Aside from the challenge of keeping air and moisture out of the reaction system, the highly reactive reagents often required in organic synthesis may be hazardous to use, including compounds that can be pyrophoric, toxic, carcinogenic, mutagenic, corrosive, and odourous (e.g. thiols). AcroSeal packaging provides a safer solution for handling these reagents by allowing removal of the reagent from the bottle under an inert atmosphere and without exposing the contents to air.