The Suzuki reaction uses a palladium complex catalyst to cross-couple a boronic acid to an organohalide

The Suzuki Cross-Coupling reaction is the coupling of an aryl or vinyl boronic acid with an aryl or vinyl halide or triflate using a palladium catalyst.

Named Reactions in Organic Synthesis


Suzuki Reaction Mechanism

Watch our video to learn more about the Suzuki Reaction and its mechanisms. 

 


Need reagents for the Suzuki Reaction?

Chem dex

If you need further help to plan your synthesis, don’t miss our new app.  Chem dex is a new tool to explore hundreds of chemical reactions, and to have access to product recommendations. Visit: thermofisher.com/chemdex.


Named Reactions eBook

Named Reactions in Organic Synthesis eBook

Download our Named Reactions eBook to learn more about the Grignard Reaction. 

 

Access 10 chapters of content about organic chemistry reactions that are named after the chemists that discovered them. This informative eBook includes quizzes so you can test your knowledge!

 


History of the Suzuki Reaction

One of the best-known cross-coupling reactions is the Suzuki or Suzuki-Miyaura reaction, where organoboron compounds and organic halides or triflates react in the presence of a palladium catalyst to form carbon-carbon bonds. First reported in 1979, this reaction offers several advantages over other cross-coupling reactions, particularly the Stille reaction, boronic acids being much less toxic and environmentally damaging than the organostannanes.


Other Transition Metal-Catalyzed Couplings

Other Transition Metal-Catalyzed Couplings include: 

For other types of reactions, visit our Named Reactions page.


Acroseal Packaging

Chemical reactions often involve the use of air- and moisture-sensitive solvents, and pyrophoric or hazardous reagents. Our AcroSeal packaging is a packaging solution designed to enable safe handling of these types of materials which are used in a variety of research and development applications, including NMR analysis and studies in drug discovery, agrochemicals, flavors and fragrances, and more. 

 

Watch our video for more information.