Automated Extraction for DNA, RNA, Protein, & Cells

As your throughput needs develop, KingFisher's automated technology is available in different models to support your process.

• KingFisher Apex
• KingFisher Apex Dx
• KingFisher Flex
• KingFisher Presto
• KingFisher Duo Prime

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KingFisher systems use biotinylated magnetic beads for targeted ligand capture. Through an automated workflow of washing, binding, and eluting, they efficiently extract and enrich DNA, RNA, proteins, and cells from complex samples.

Learn more: How magnetic bead-based automation technology works

KingFisher automated extraction systems can be applied to many workflows to support multiple initiatives in your lab.

• Next generation sequencing (NGS)
• Immunoprecipitation

• qRT-PCR
• Mass spectrometry

Nucleic acid workflows can be seamlessly automated with the right kits and reagents optimized to work with KingFisher systems.

Explore:  Automated nucleic acid extraction workstation setup

Nucleic acid extraction kits compatible with KingFisher automated systems:

• MagMAX kits for nucleic acid extraction
• FFPE DNA/RNA extraction 
• Total RNA and mRNA extraction
• Viral nucleic acids extraction 
• Cell-free nucleic acid DNA extraction
• Plant DNA isolation
• Plant RNA isolation
• Dynabeads Streptavidin for NGS target enrichment

KingFisher instruments paired with Dynabeads offer the best balance between yield and consistency when purifying proteins using immunoprecipitation.

• Automated protein immunoprecipitation with Dynabeads products and KingFisher systems
• Streptavidin for protein purification 
• Protein A beads for immunoprecipitation
• Protein G beads for immunoprecipitation
• Immunoprecipitation with Dynabeads Sheep anti-Mouse IgG
• Immunoprecipitation with Dynabeads Sheep anti-Rabbit IgG
• Immunoprecipitation with DynaGreen magnetic beads

Explore: Automating protein purification for peptide mapping

Automating cell and exosome isolation with KingFisher systems helps to reduce hands-on time, prevent cross-contamination, and deliver consistent outcomes. It is easy—set up, press start, walk away, and have results in just 40 minutes.

• Automated cell isolation 
• T-cell activation and expansion
• Automated exosome isolation

Explore:  KingFisher Flex System with Dynabeads reagents: A consistent approach for exosome pull-down and analysis

KingFisher instruments save you valuable time by removing manual steps and reducing overall processing time, even when compared with other instruments.

KingFisher automated extraction instruments reduce user processing errors while increasing the reproducibility of your results. Our data show that samples processed with KingFisher instruments show consistent results across runs and different users, which is important for more sensitive downstream applications such as qPCR, NGS, digital PCR, and mass spectrometry.

Automation achieves cost savings at scale when viewing labor and material demand, let alone a happier employee doing less manual work.