Small Molecule Bioanalysis and DMPK Studies

Understanding your molecules is critical, and ensuring accuracy throughout sample preparation, analysis and data interpretation is paramount when it comes to your DMPK studies. Regardless of matrix complexity, sample throughput or sensitivity and linearity requirements, find out what it takes to meet these challenges with ease – all in a 21 CFR Part 11 and GxP compliant environment.

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Remove variability and optimize high-throughput laboratory workflows. Thermo Scientific SOLAµ Solid Phase Extraction (SPE) Plates are designed for bioanalytical research analysts who require cleaner, highly reproducible, and robust sample extraction using very low sample and solvent volumes in high-throughput workflows. SOLAµ Well Plates achieve this due to the unique, award winning innovative frit-less SPE technology.

Designed with innovative technology and fine detail, the Thermo Scientific Vanquish Horizon UHPLC System delivers a new standard in high-end UHPLC – more results with better separations and easier interaction simultaneously, without compromise.

For the most complex samples and the highest throughput, you can be sure that the Vanquish Horizon delivers the utmost confidence for your LC-MS quantitative workflows.

 Vanquish UHPLC brochure

Productivity has been redefined with the Thermo Scientific Orbitrap Exploris 120 mass spectrometer due to its ability to provide consistently accurate results for screening and quantitation applications. Keep your laboratory running seamlessly with reproducible and sensitive results, all on a rugged instrument platform.

Your samples are both precious and limited, the Thermo Scientific TSQ Altis Triple Quadrupole Mass Spectrometer ensures supreme quantitative performance without compromise.

Meet your analytical challenges and goals every day, for every sample with robust, sensitive and efficient targeted quantitation workflows.

 TSQ Altis brochure
 Application note: Quantitative analysis of drug candidates in plasma

Easily answer critical analytical challenges during targeted quantitation workflows in your laboratory. With the sensitivity and reproducibility to quantitate any molecule in complex biological matrices, the Thermo Scientific TSQ Quantis Triple Quadrupole Mass Spectrometer delivers – workflow driven solutions for absolute confidence.

 TSQ Quantis brochure

The Thermo Scientific Watson LIMS Software for Biolanalytical Laboratories, installed in 18 of the top 20 global pharmaceutical organizations, is widely used in leading biotechnology and contract research organizations worldwide. The Watson LIMS facilitates efficient study design and data transfer while streamlining assay validation, bioanalysis, instrument interfacing, sample tracking, results reporting and regulatory compliance.

Thermo Scientific Chromeleon 7.3 Chromatography Data System software unifies workflows for chromatography and routine quantitative MS analysis, providing full integration of Thermo Scientific's gas chromatography (GC)-MS/MS and liquid chromatography (LC)-MS/MS instruments in a 21 CFR Part 11 and GxP compliant environment, as well as more than 400 other instruments from over 15 different vendors. Quickly and easily process and report UV and MS data in one application. Run your analyses in an enterprise environment – from method creation through to quantitation and library-based compound identification.

With Thermo Scientific TraceFinder Software you have the power to develop robust and reliable methods, whilst increasing productivity within your laboratory for your targeted screening and routine quantitative assays; address the challenges both today and tomorrow with unparalleled ease – quantitation with confidence.

 TraceFinder Software brochure