Product References
Protocol for large scale whole blood immune monitoring by mass cytometry and Cyto Quality Pipeline.
STAR protocols
Rybakowska P,Van Gassen S,Martorell Marugán J,Quintelier K,Saeys Y,Alarcón-Riquelme ME,Marañón C
14-0038-82 was used in Flow Cytometry, Functional Assay, Immunohistochemistry (Frozen) to describe the steps to stimulate, fix, and freeze blood samples before acquisition to make them suitable for retrospective studies.
Fri Dec 16 00:00:00 EST 2022
The impact of maternal SARS-CoV-2 vaccination and first trimester infection on feto-maternal immune responses.
American journal of reproductive immunology (New York, N.Y. : 1989)
Juttukonda LJ,Wachman EM,Boateng J,Clarke K,Snyder-Cappione J,Taglauer ES
14-0038-82 was used in Flow Cytometry, Functional Assay, Immunohistochemistry (Frozen) to conclude that COVID-19 infection in the first trimester did not cause significant decidual leukocyte or cytokine changes at the maternal-fetal interface, and that vaccination was not associated with decidual inflammation, supporting the safety of SARS-CoV-2 vaccination during pregnancy.
Thu Dec 01 00:00:00 EST 2022
Aberrant gut-microbiota-immune-brain axis development in premature neonates with brain damage.
Cell host & microbe
Seki D,Mayer M,Hausmann B,Pjevac P,Giordano V,Goeral K,Unterasinger L,Klebermaß-Schrehof K,De Paepe K,Van de Wiele T,Spittler A,Kasprian G,Warth B,Berger A,Berry D,Wisgrill L
Published figure using CD3 monoclonal antibody (Product # 14-0038-82) in Flow Cytometry
Wed Oct 13 00:00:00 EDT 2021
Bispecific antibody target pair discovery by high-throughput phenotypic screening using in vitro combinatorial Fab libraries.
mAbs
Bhatta P,Whale KD,Sawtell AK,Thompson CL,Rapecki SE,Cook DA,Twomey BM,Mennecozzi M,Starkie LE,Barry EMC,Peters SJ,Kamal AM,Finney HM
14-0038-82 was used in Flow Cytometry to screen of hundreds of target combinations using a high-throughput, combinatorial, phenotypic screening approach using a new bispecific antibody target discovery format.
Thu Oct 14 00:00:00 EDT 2021
Single-cell RNA sequencing reveals ex vivo signatures of SARS-CoV-2-reactive T cells through 'reverse phenotyping'.
Nature communications
Fischer DS,Ansari M,Wagner KI,Jarosch S,Huang Y,Mayr CH,Strunz M,Lang NJ,D'Ippolito E,Hammel M,Mateyka L,Weber S,Wolff LS,Witter K,Fernandez IE,Leuschner G,Milger K,Frankenberger M,Nowak L,Heinig-Menhard K,Koch I,Stoleriu MG,Hilgendorff A,Behr J,Pichlmair A,Schubert B,Theis FJ,Busch DH,Schiller HB,Schober K
Published figure using CD3 monoclonal antibody (Product # 14-0038-82) in Flow Cytometry
Mon Jul 26 00:00:00 EDT 2021
Single-cell transcriptomics reveals regulators underlying immune cell diversity and immune subtypes associated with prognosis in nasopharyngeal carcinoma.
Cell research
Chen YP,Yin JH,Li WF,Li HJ,Chen DP,Zhang CJ,Lv JW,Wang YQ,Li XM,Li JY,Zhang PP,Li YQ,He QM,Yang XJ,Lei Y,Tang LL,Zhou GQ,Mao YP,Wei C,Xiong KX,Zhang HB,Zhu SD,Hou Y,Sun Y,Dean M,Amit I,Wu K,Kuang DM,Li GB,Liu N,Ma J
Published figure using CD3 monoclonal antibody (Product # 14-0038-82) in Flow Cytometry
Sun Nov 01 00:00:00 EDT 2020
Defective glycosylation and multisystem abnormalities characterize the primary immunodeficiency XMEN disease.
The Journal of clinical investigation
Ravell JC,Matsuda-Lennikov M,Chauvin SD,Zou J,Biancalana M,Deeb SJ,Price S,Su HC,Notarangelo G,Jiang P,Morawski A,Kanellopoulou C,Binder K,Mukherjee R,Anibal JT,Sellers B,Zheng L,He T,George AB,Pittaluga S,Powers A,Kleiner DE,Kapuria D,Ghany M,Hunsberger S,Cohen JI,Uzel G,Bergerson J,Wolfe L,Toro C,Gahl W,Folio LR,Matthews H,Angelus P,Chinn IK,Orange JS,Trujillo-Vargas CM,Franco JL,Orrego-Arango J,Gutiérrez-Hincapié S,Patel NC,Raymond K,Patiroglu T,Unal E,Karakukcu M,Day AG,Mehta P,Masutani E,De Ravin SS,Malech HL,Altan-Bonnet G,Rao VK,Mann M,Lenardo MJ
14-0038 was used in Flow cytometry/Cell sorting to provide new clinical and pathophysiological foundations with important ramifications for the diagnosis and treatment of XMEN disease.
Thu Jan 02 00:00:00 EST 2020
Aging affects responsiveness of peripheral blood mononuclear cells to immunosuppression of periodontal ligament stem cells.
The Journal of international medical research
Li X,Zhang B,Wang H,Zhao X,Zhang Z,Ding G,Wei F
Published figure using CD3 monoclonal antibody (Product # 14-0038-82) in Flow Cytometry
Wed Jul 01 00:00:00 EDT 2020
Involvement of natural killer cells in the pathogenesis of endometriosis in patients with pelvic pain.
The Journal of international medical research
He J,Xu Y,Yi M,Gu C,Zhu Y,Hu G
Published figure using CD3 monoclonal antibody (Product # 14-0038-82) in Flow Cytometry
Wed Jul 01 00:00:00 EDT 2020
Dendritic Cell Maturation Regulates TSPAN7 Function in HIV-1 Transfer to CD4+ T Lymphocytes.
Frontiers in cellular and infection microbiology
Perot BP,García-Paredes V,Luka M,Ménager MM
Published figure using CD3 monoclonal antibody (Product # 14-0038-82) in Flow Cytometry
Wed Mar 17 00:00:00 EDT 2021
Th2-like T Follicular Helper Cells Promote Functional Antibody Production during Plasmodium falciparum Infection.
Cell reports. Medicine
Chan JA,Loughland JR,de Labastida Rivera F,SheelaNair A,Andrew DW,Dooley NL,Wines BD,Amante FH,Webb L,Hogarth PM,McCarthy JS,Beeson JG,Engwerda CR,Boyle MJ
Published figure using CD3 monoclonal antibody (Product # 14-0038-82) in Flow Cytometry
Tue Dec 22 00:00:00 EST 2020
High-affinity mutant Interleukin-13 targeted CAR T cells enhance delivery of clickable biodegradable fluorescent nanoparticles to glioblastoma.
Bioactive materials
Kim GB,Aragon-Sanabria V,Randolph L,Jiang H,Reynolds JA,Webb BS,Madhankumar A,Lian X,Connor JR,Yang J,Dong C
14-0038 was used in Flow cytometry/Cell sorting to demonstrate the potential of a multidisciplinary combination of fluorescent, therapeutic nanoparticles and CAR T cells in brain tumor treatment.
Tue Sep 01 00:00:00 EDT 2020
DNA hypomethylation promotes transposable element expression and activation of immune signaling in renal cell cancer.
JCI insight
de Cubas AA,Dunker W,Zaninovich A,Hongo RA,Bhatia A,Panda A,Beckermann KE,Bhanot G,Ganesan S,Karijolich J,Rathmell WK
14-0038 was used in Flow cytometry/Cell sorting to identify a potential strategy to induce TE expression through inhibition of DNA methylation in modulating T cell action via regulation of the innate antiviral pathway.
Thu Jun 04 00:00:00 EDT 2020
Loss of ARPC1B impairs cytotoxic T lymphocyte maintenance and cytolytic activity.
The Journal of clinical investigation
Randzavola LO,Strege K,Juzans M,Asano Y,Stinchcombe JC,Gawden-Bone CM,Seaman MN,Kuijpers TW,Griffiths GM
Published figure using CD3 monoclonal antibody (Product # 14-0038-82) in Flow Cytometry
Mon Dec 02 00:00:00 EST 2019
Skewed T cell responses to Epstein-Barr virus in long-term asymptomatic kidney transplant recipients.
PloS one
Nakid-Cordero C,Arzouk N,Gauthier N,Tarantino N,Larsen M,Choquet S,Burrel S,Autran B,Vieillard V,Guihot A
Published figure using CD3 monoclonal antibody (Product # 14-0038-82) in Flow Cytometry
Mon Mar 30 00:00:00 EDT 2020
Inflammation induced by incomplete radiofrequency ablation accelerates tumor progression and hinders PD-1 immunotherapy.
Nature communications
Shi L,Wang J,Ding N,Zhang Y,Zhu Y,Dong S,Wang X,Peng C,Zhou C,Zhou L,Li X,Shi H,Wu W,Long X,Wu C,Liao W
Published figure using CD3 monoclonal antibody (Product # 14-0038-82) in Flow Cytometry
Thu Nov 28 00:00:00 EST 2019
Deep single-cell RNA sequencing data of individual T cells from treatment-naïve colorectal cancer patients.
Scientific data
Zhang Y,Zheng L,Zhang L,Hu X,Ren X,Zhang Z
14-0038-82 was used in Flow Cytometry to investigate the basic properties of tumour-infiltrating T cells (TILs) such as the functional state, migratory capability and clonal expansion.
Wed Jul 24 00:00:00 EDT 2019
Gpr174-deficient regulatory T cells decrease cytokine storm in septic mice.
Cell death & disease
Qiu D,Chu X,Hua L,Yang Y,Li K,Han Y,Yin J,Zhu M,Mu S,Sun Z,Tong C,Song Z
14-0038-82 was used in Flow cytometry/Cell sorting to investigate the role of G protein-coupled receptor 174 (Gpr174) in regulating suppressive function of regulatory T cells (Treg cells) and the underlying mechanism of Gpr174-deficient Treg cells in controlling cytokine storm of sepsis.
Fri Mar 08 00:00:00 EST 2019
Regulatory T cells use arginase 2 to enhance their metabolic fitness in tissues.
JCI insight
Lowe MM,Boothby I,Clancy S,Ahn RS,Liao W,Nguyen DN,Schumann K,Marson A,Mahuron KM,Kingsbury GA,Liu Z,Munoz Sandoval P,Rodriguez RS,Pauli ML,Taravati K,Arron ST,Neuhaus IM,Harris HW,Kim EA,Shin US,Krummel MF,Daud A,Scharschmidt TC,Rosenblum MD
14-0038 was used in Flow cytometry/Cell sorting to compare healthy skin Tregs with those in peripheral blood, inflamed psoriatic skin, and metastatic melanoma.
Thu Dec 19 00:00:00 EST 2019
Biallelic mutations in DNA ligase 1 underlie a spectrum of immune deficiencies.
The Journal of clinical investigation
Maffucci P,Chavez J,Jurkiw TJ,O'Brien PJ,Abbott JK,Reynolds PR,Worth A,Notarangelo LD,Felgentreff K,Cortes P,Boisson B,Radigan L,Cobat A,Dinakar C,Ehlayel M,Ben-Omran T,Gelfand EW,Casanova JL,Cunningham-Rundles C
Published figure using CD3 monoclonal antibody (Product # 14-0038-82) in Flow Cytometry
Mon Dec 03 00:00:00 EST 2018
FUNDAMANT: an interventional 72-week phase 1 follow-up study of AADvac1, an active immunotherapy against tau protein pathology in Alzheimer's disease.
Alzheimer's research & therapy
Novak P,Schmidt R,Kontsekova E,Kovacech B,Smolek T,Katina S,Fialova L,Prcina M,Parrak V,Dal-Bianco P,Brunner M,Staffen W,Rainer M,Ondrus M,Ropele S,Smisek M,Sivak R,Zilka N,Winblad B,Novak M
14-0038 was used in Flow cytometry/Cell sorting to follow-up on patients following a 24-week phase 1 trial on the active vaccine AADvac1 against pathological tau protein.
Wed Oct 24 00:00:00 EDT 2018
T Cells on Engineered Substrates: The Impact of TCR Clustering Is Enhanced by LFA-1 Engagement.
Frontiers in immunology
Benard E,Nunès JA,Limozin L,Sengupta K
14-0038 was used in Functional assays to indicate complementary role for LFA-1 and CD28 in the regulation and putative coupling of TCR micro-clusters to actin.
Mon Sep 30 00:00:00 EDT 2019
Dysfunction of CD19+CD24hiCD27+ B regulatory cells in patients with bullous pemphigoid.
Scientific reports
Liu Z,Dang E,Li B,Qiao H,Jin L,Zhang J,Wang G
14-0038 was used in Flow cytometry/Cell sorting to compare the frequency and function of B regulatory cells from the peripheral blood of bullous pemphigoid patients and healthy controls.
Mon Jan 15 00:00:00 EST 2018
Blocking the recruitment of naive CD4+ T cells reverses immunosuppression in breast cancer.
Cell research
Su S,Liao J,Liu J,Huang D,He C,Chen F,Yang L,Wu W,Chen J,Lin L,Zeng Y,Ouyang N,Cui X,Yao H,Su F,Huang JD,Lieberman J,Liu Q,Song E
Published figure using CD3 monoclonal antibody (Product # 14-0038-82) in Flow Cytometry
Sat Apr 01 00:00:00 EDT 2017
Dual role of tumour-infiltrating T helper 17 cells in human colorectal cancer.
Gut
Amicarella F,Muraro MG,Hirt C,Cremonesi E,Padovan E,Mele V,Governa V,Han J,Huber X,Droeser RA,Zuber M,Adamina M,Bolli M,Rosso R,Lugli A,Zlobec I,Terracciano L,Tornillo L,Zajac P,Eppenberger-Castori S,Trapani F,Oertli D,Iezzi G
14-0038 was used in an ELISA assay to investigate clinical relevance, phenotypes and functional features of CRC-infiltrating, IL-17- producing cells.
Sat Apr 01 00:00:00 EDT 2017
NK-Cell Recruitment Is Necessary for Eradication of Peritoneal Carcinomatosis with an IL12-Expressing Maraba Virus Cellular Vaccine.
Cancer immunology research
Alkayyal AA,Tai LH,Kennedy MA,de Souza CT,Zhang J,Lefebvre C,Sahi S,Ananth AA,Mahmoud AB,Makrigiannis AP,Cron GO,Macdonald B,Marginean EC,Stojdl DF,Bell JC,Auer RC
14-0038 was used in Flow cytometry/Cell sorting to suggest that an MG1-IL12-ICV is a promising therapy that could provide benefit to the thousands of patients diagnosed with PC each year.
Wed Mar 01 00:00:00 EST 2017
Follicular Regulatory T Cells Are Highly Permissive to R5-Tropic HIV-1.
Journal of virology
Miller SM,Miles B,Guo K,Folkvord J,Meditz AL,McCarter MD,Levy DN,MaWhinney S,Santiago ML,Connick E
Published figure using CD3 monoclonal antibody (Product # 14-0038-82) in Flow Cytometry
Fri Sep 01 00:00:00 EDT 2017
Frequency of CD4+CD161+ T Cell and Interleukin-10 Expression in Inflammatory Bowel Diseases.
Acta histochemica et cytochemica
Tsuchiya K,Ikeda T,Batmunkh B,Choijookhuu N,Ishizaki H,Hotokezaka M,Hishikawa Y,Nanashima A
14-0038 was used in Flow cytometry/Cell sorting to investigate the expression of CD4(+)CD161(+) T cells and IL-10 in inflammatory bowel disease patients.
Tue Feb 28 00:00:00 EST 2017
Antigen receptor-redirected T cells derived from hematopoietic precursor cells lack expression of the endogenous TCR/CD3 receptor and exhibit specific antitumor capacities.
Oncoimmunology
Van Caeneghem Y,De Munter S,Tieppo P,Goetgeluk G,Weening K,Verstichel G,Bonte S,Taghon T,Leclercq G,Kerre T,Debets R,Vermijlen D,Abken H,Vandekerckhove B
Published figure using CD3 monoclonal antibody (Product # 14-0038-82) in Flow Cytometry
Tue Jan 12 00:00:00 EST 2021
Tissue factor expression by myeloid cells contributes to protective immune response against Mycobacterium tuberculosis infection.
European journal of immunology
Venkatasubramanian S,Tripathi D,Tucker T,Paidipally P,Cheekatla S,Welch E,Raghunath A,Jeffers A,Tvinnereim AR,Schechter ME,Andrade BB,Mackman N,Idell S,Vankayalapati R
14-0038 was used in Flow cytometry/Cell sorting to determine the role of tissue factor expressed by myeloid cells during Mycobacterium tuberculosis infection.
Mon Feb 01 00:00:00 EST 2016
Distinct Transcriptional Changes and Epithelial-Stromal Interactions Are Altered in Early-Stage Colon Cancer Development.
Molecular cancer research : MCR
Mo A,Jackson S,Varma K,Carpino A,Giardina C,Devers TJ,Rosenberg DW
14-0038 was used in Immunofluorescence in immunohistochemistry on frozen tissues to perform a detailed characterisation of aberrant crypt foci in the human colon to better understand the epithelial-stromal interactions that regulate their progression to malignancy.
Thu Sep 01 00:00:00 EDT 2016
Interaction among activated lymphocytes and mesenchymal cells through podoplanin is critical for a high IL-17 secretion.
Arthritis research & therapy
Noack M,Ndongo-Thiam N,Miossec P
Published figure using CD3 monoclonal antibody (Product # 14-0038-82) in Flow Cytometry
Thu Jun 23 00:00:00 EDT 2016
MAIT cells are activated during human viral infections.
Nature communications
van Wilgenburg B,Scherwitzl I,Hutchinson EC,Leng T,Kurioka A,Kulicke C,de Lara C,Cole S,Vasanawathana S,Limpitikul W,Malasit P,Young D,Denney L,Moore MD,Fabris P,Giordani MT,Oo YH,Laidlaw SM,Dustin LB,Ho LP,Thompson FM,Ramamurthy N,Mongkolsapaya J,Willberg CB,Screaton GR,Klenerman P
Published figure using CD3 monoclonal antibody (Product # 14-0038-82) in Flow Cytometry
Thu Jun 23 00:00:00 EDT 2016
The Effect of Chronic Hepatitis B Virus Infection on BDCA3+ Dendritic Cell Frequency and Function.
PloS one
van der Aa E,Buschow SI,Biesta PJ,Janssen HL,Woltman AM
14-0038 was used in Flow cytometry/Cell sorting to investigate the role of BDCA3+ DCs in immune response against the hepititis B virus, showing that BDCA3+ DCs are available in the blood and on site in HBV infected livers.
Wed Aug 02 00:00:00 EDT 2017
Distinct Metabolic Requirements of Exhausted and Functional Virus-Specific CD8 T Cells in the Same Host.
Cell reports
Schurich A,Pallett LJ,Jajbhay D,Wijngaarden J,Otano I,Gill US,Hansi N,Kennedy PT,Nastouli E,Gilson R,Frezza C,Henson SM,Maini MK
14-0038 was used in Flow cytometry/Cell sorting to demonstrate that functional and exhausted human-virus-specific CD8 T-cells have distinct metabolic phenotypes, shaping their effector capacity.
Tue Aug 02 00:00:00 EDT 2016
Atypical natural killer T-cell receptor recognition of CD1d-lipid antigens.
Nature communications
Le Nours J,Praveena T,Pellicci DG,Gherardin NA,Ross FJ,Lim RT,Besra GS,Keshipeddy S,Richardson SK,Howell AR,Gras S,Godfrey DI,Rossjohn J,Uldrich AP
14-0038 was used in Flow cytometry/Cell sorting to try to determine the diversity of the NKT cell repertoire and the ensuing interactions with the CD1d-antigen.
Mon Feb 15 00:00:00 EST 2016
Jejunal T Cell Inflammation in Human Obesity Correlates with Decreased Enterocyte Insulin Signaling.
Cell metabolism
Monteiro-Sepulveda M,Touch S,Mendes-Sá C,André S,Poitou C,Allatif O,Cotillard A,Fohrer-Ting H,Hubert EL,Remark R,Genser L,Tordjman J,Garbin K,Osinski C,Sautès-Fridman C,Leturque A,Clément K,Brot-Laroche E
14-0038 was used in Flow cytometry/Cell sorting to study inflammation of the absorptive small intestine in obese and diabetic patients.
Tue Jul 07 00:00:00 EDT 2015
A polymorphism in a phosphotyrosine signalling motif of CD229 (Ly9, SLAMF3) alters SH2 domain binding and T-cell activation.
Immunology
Margraf S,Garner LI,Wilson TJ,Brown MH
14-0038 was used in Functional assays to identify potential mechanisms by which a single single-nucleotide polymorphisms can perturb fine-tuning in the immune system, with significant functional consequences.
Sun Nov 01 00:00:00 EDT 2015
Thymic HIV-2 infection uncovers posttranscriptional control of viral replication in human thymocytes.
Journal of virology
Nunes-Cabaço H,Matoso P,Foxall RB,Tendeiro R,Pires AR,Carvalho T,Pinheiro AI,Soares RS,Sousa AE
14-0038 was used in Flow cytometry/Cell sorting to assess the direct impact of HIV-2 infection on the human thymus.
Sun Feb 01 00:00:00 EST 2015
The Nrf2 activator tBHQ inhibits T cell activation of primary human CD4 T cells.
Cytokine
Turley AE,Zagorski JW,Rockwell CE
14-0038 was used in Functional assays to investigate the effect of Nrf2 on human immune cells, showing that the Nrf2 activator tBHQ inhibits T cell activation.
Sun Feb 01 00:00:00 EST 2015
Follicular regulatory T cells impair follicular T helper cells in HIV and SIV infection.
Nature communications
Miles B,Miller SM,Folkvord JM,Kimball A,Chamanian M,Meditz AL,Arends T,McCarter MD,Levy DN,Rakasz EG,Skinner PJ,Connick E
Published figure using CD3 monoclonal antibody (Product # 14-0038-82) in Flow Cytometry
Tue Oct 20 00:00:00 EDT 2015
Higher Frequency of NK and CD4+ T-Cells in Mucosa and Potent Cytotoxic Response in HIV Controllers.
PloS one
Taborda NA,González SM,Alvarez CM,Correa LA,Montoya CJ,Rugeles MT
14-0038 was used in Flow cytometry/Cell sorting to investigate the frequency, phenotype and activity of T and NK cells in HIV controllers, showing higher frequencies of NK and CD4+ T-Cells and potent cytotoxic response.
Fri May 13 00:00:00 EDT 2016
Transfer of mRNA Encoding Invariant NKT Cell Receptors Imparts Glycolipid Specific Responses to T Cells and γδT Cells.
PloS one
Shimizu K,Shinga J,Yamasaki S,Kawamura M,Dörrie J,Schaft N,Sato Y,Iyoda T,Fujii S
14-0038 was used in Flow cytometry/Cell sorting to transfect innate and adaptive lymphocytes with the human NKT cell-derived TCRα and β chain mRNA, to show a potential new approach to tumor immunotherapy.
Mon Mar 28 00:00:00 EDT 2016
Safety and immunogenicity of a candidate tuberculosis vaccine MVA85A delivered by aerosol in BCG-vaccinated healthy adults: a phase 1, double-blind, randomised controlled trial.
The Lancet. Infectious diseases
Satti I,Meyer J,Harris SA,Manjaly Thomas ZR,Griffiths K,Antrobus RD,Rowland R,Ramon RL,Smith M,Sheehan S,Bettinson H,McShane H
14-0038 was used in Flow cytometry/Cell sorting to compare the safety and immunogenicity of aerosol-administered and intradermally administered MVA85A, a candidate vaccine against tuberculosis.
Wed Oct 01 00:00:00 EDT 2014
Human mesenchymal stromal cells modulate T-cell responses through TNF-α-mediated activation of NF-κB.
European journal of immunology
Dorronsoro A,Ferrin I,Salcedo JM,Jakobsson E,Fernández-Rueda J,Lang V,Sepulveda P,Fechter K,Pennington D,Trigueros C
Published figure using CD3 monoclonal antibody (Product # 14-0038-82) in Flow Cytometry
Sat Feb 01 00:00:00 EST 2014
Signal transduction by different forms of the γδ T cell-specific pattern recognition receptor WC1.
Journal of immunology (Baltimore, Md. : 1950)
Chen C,Hsu H,Hudgens E,Telfer JC,Baldwin CL
14-0038 was used in an ELISA assay to assess IL-2 production in response to differences in expression of the WC1 gene.
Tue Jul 01 00:00:00 EDT 2014
A comparison of DNA methylation specific droplet digital PCR (ddPCR) and real time qPCR with flow cytometry in characterizing human T cells in peripheral blood.
Epigenetics
Wiencke JK,Bracci PM,Hsuang G,Zheng S,Hansen H,Wrensch MR,Rice T,Eliot M,Kelsey KT
Published figure using CD3 monoclonal antibody (Product # 14-0038-82) in Flow Cytometry
Wed Oct 01 00:00:00 EDT 2014
The antiangiogenic insulin receptor substrate-1 antisense oligonucleotide aganirsen impairs AU-rich mRNA stability by reducing 14-3-3β-tristetraprolin protein complex, reducing inflammation and psoriatic lesion size in patients.
The Journal of pharmacology and experimental therapeutics
Colin S,Darné B,Kadi A,Ferry A,Favier M,Lesaffre C,Conduzorgues JP,Al-Mahmood S,Doss N
14-0038 was used in Immunohistochemistry to demonstrate that aganirsen is the first of a new generation of antiangiogenic medicines combining anti-inflammatory activities.
Tue Apr 01 00:00:00 EDT 2014
Trypan blue exclusion assay by flow cytometry.
Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologicas
Avelar-Freitas BA,Almeida VG,Pinto MC,Mourão FA,Massensini AR,Martins-Filho OA,Rocha-Vieira E,Brito-Melo GE
Published figure using CD3 monoclonal antibody (Product # 14-0038-82) in Flow Cytometry
Tue Apr 01 00:00:00 EDT 2014
Induction of type I and type III interferons by Borrelia burgdorferi correlates with pathogenesis and requires linear plasmid 36.
PloS one
Krupna-Gaylord MA,Liveris D,Love AC,Wormser GP,Schwartz I,Petzke MM
Published figure using CD3 monoclonal antibody (Product # 14-0038-82) in Flow Cytometry
Thu Mar 12 00:00:00 EDT 2015
Novel lentiviral vectors with mutated reverse transcriptase for mRNA delivery of TALE nucleases.
Scientific reports
Mock U,Riecken K,Berdien B,Qasim W,Chan E,Cathomen T,Fehse B
Published figure using CD3 monoclonal antibody (Product # 14-0038-82) in Flow Cytometry
Thu Sep 18 00:00:00 EDT 2014
Recombinant influenza virus carrying the respiratory syncytial virus (RSV) F85-93 CTL epitope reduces RSV replication in mice.
Journal of virology
De Baets S,Schepens B,Sedeyn K,Schotsaert M,Roose K,Bogaert P,Fiers W,Saelens X
Published figure using CD3 monoclonal antibody (Product # 14-0038-82) in Flow Cytometry
Fri Mar 01 00:00:00 EST 2013
Intercellular adhesion molecule 1 mediates migration of Th1 and Th17 cells across human retinal vascular endothelium.
Investigative ophthalmology & visual science
Bharadwaj AS,Schewitz-Bowers LP,Wei L,Lee RW,Smith JR
14-0038 was used in Flow cytometry/Cell sorting to investigate the ability of human Th1- and Th17-polarised cells to cross a simulated human retinal endothelium, and examined the role of IgG superfamily members in this process.
Wed Oct 23 00:00:00 EDT 2013
MHC multimer-guided and cell culture-independent isolation of functional T cell receptors from single cells facilitates TCR identification for immunotherapy.
PloS one
Dössinger G,Bunse M,Bet J,Albrecht J,Paszkiewicz PJ,Weißbrich B,Schiedewitz I,Henkel L,Schiemann M,Neuenhahn M,Uckert W,Busch DH
Published figure using CD3 monoclonal antibody (Product # 14-0038-82) in Flow Cytometry
Mon Nov 11 00:00:00 EST 2013
Antibody-mediated targeting of the Orai1 calcium channel inhibits T cell function.
PloS one
Cox JH,Hussell S,Søndergaard H,Roepstorff K,Bui JV,Deer JR,Zhang J,Li ZG,Lamberth K,Kvist PH,Padkjær S,Haase C,Zahn S,Odegard VH
14-0038 was used in Functional assays to investigate the use of ion channels as therapeutic targets for the treatment of autoimmunity and other diseases.
Mon Oct 06 00:00:00 EDT 2014
Mycobacterial phosphatidylinositol mannoside 6 (PIM6) up-regulates TCR-triggered HIV-1 replication in CD4+ T cells.
PloS one
Rodriguez ME,Loyd CM,Ding X,Karim AF,McDonald DJ,Canaday DH,Rojas RE
14-0038 was used in Functional assays to study the direct effects of different MTB molecules on HIV-1 replication in T cells.
Tue Aug 05 00:00:00 EDT 2014
Epigenetic biomarkers of T-cells in human glioma.
Epigenetics
Wiencke JK,Accomando WP,Zheng S,Patoka J,Dou X,Phillips JJ,Hsuang G,Christensen BC,Houseman EA,Koestler DC,Bracci P,Wiemels JL,Wrensch M,Nelson HH,Kelsey KT
Published figure using CD3 monoclonal antibody (Product # 14-0038-82) in Flow Cytometry
Sat Dec 01 00:00:00 EST 2012
Ulcerative colitis impairs the acylethanolamide-based anti-inflammatory system reversal by 5-aminosalicylic acid and glucocorticoids.
PloS one
Suárez J,Romero-Zerbo Y,Márquez L,Rivera P,Iglesias M,Bermúdez-Silva FJ,Andreu M,Rodríguez de Fonseca F
Published figure using CD3 monoclonal antibody (Product # 14-0038-82) in Immunofluorescence
Thu Dec 13 00:00:00 EST 2012
Ulcerative colitis impairs the acylethanolamide-based anti-inflammatory system reversal by 5-aminosalicylic acid and glucocorticoids.
PloS one
Suárez J,Romero-Zerbo Y,Márquez L,Rivera P,Iglesias M,Bermúdez-Silva FJ,Andreu M,Rodríguez de Fonseca F
Published figure using CD3 monoclonal antibody (Product # 14-0038-82) in Immunofluorescence
Thu Dec 13 00:00:00 EST 2012
TNF-α and TGF-β counter-regulate PD-L1 expression on monocytes in systemic lupus erythematosus.
Scientific reports
Ou JN,Wiedeman AE,Stevens AM
14-0038 was used in Flow cytometry/Cell sorting to investigate the mechanism for PD-L1 dysregulation on lupus monocytes.
Fri Apr 12 00:00:00 EDT 2013
Defective response of CD4(+) T cells to retinoic acid and TGFβ in systemic lupus erythematosus.
Arthritis research & therapy
Sobel ES,Brusko TM,Butfiloski EJ,Hou W,Li S,Cuda CM,Abid AN,Reeves WH,Morel L
14-0038 was used in Flow cytometry/Cell sorting to investigate the impaired integration of the TGFβ and RA signals in SLE T cells and implicate the PBX1 gene in this process.
Mon Jun 27 00:00:00 EDT 2011
HLA-G level on monocytoid dendritic cells correlates with regulatory T-cell Foxp3 expression in liver transplant tolerance.
Transplantation
Castellaneta A,Mazariegos GV,Nayyar N,Zeevi A,Thomson AW
14-0038 was used in Flow cytometry/Cell sorting to investigate the correlation between HLA-G level on monocytoid dendritic cells and regulatory T cell Foxp3 expression in liver transplant tolerance.
Fri May 27 00:00:00 EDT 2011
Immunostaining of PD-1/PD-Ls in liver tissues of patients with hepatitis and hepatocellular carcinoma.
World journal of gastroenterology
Wang BJ,Bao JJ,Wang JZ,Wang Y,Jiang M,Xing MY,Zhang WG,Qi JY,Roggendorf M,Lu MJ,Yang DL
14-0038 was used in Immunohistochemistry to investigate the expression of PD-1, PD-L1 and PD-L2 in liver tissues in the context of chronic hepatitis and hepatocellular carcinoma.
Thu Jul 28 00:00:00 EDT 2011
Accumulation of natural killer T cells in progressive nonalcoholic fatty liver disease.
Hepatology (Baltimore, Md.)
Syn WK,Oo YH,Pereira TA,Karaca GF,Jung Y,Omenetti A,Witek RP,Choi SS,Guy CD,Fearing CM,Teaberry V,Pereira FE,Adams DH,Diehl AM
Published figure using CD3 monoclonal antibody (Product # 14-0038-82) in Immunohistochemistry
Tue Jun 01 00:00:00 EDT 2010
Human Th1 cells that express CD300a are polyfunctional and after stimulation up-regulate the T-box transcription factor eomesodermin.
PloS one
Narayanan S,Silva R,Peruzzi G,Alvarez Y,Simhadri VR,Debell K,Coligan JE,Borrego F
14-0038 was used in Functional assays to investigate a subset within the CD4 T cell population defined by expression of the immunomodulatory receptor CD300a.
Thu May 13 00:00:00 EDT 2010
Lung dendritic cell expression of maturation molecules increases with worsening chronic obstructive pulmonary disease.
American journal of respiratory and critical care medicine
Freeman CM,Martinez FJ,Han MK,Ames TM,Chensue SW,Todt JC,Arenberg DA,Meldrum CA,Getty C,McCloskey L,Curtis JL
14-0038 was used in Flow cytometry/Cell sorting to determine the expression of maturation molecules by individual DC subsets in relationship to COPD stage.
Tue Dec 15 00:00:00 EST 2009
A role for human skin-resident T cells in wound healing.
The Journal of experimental medicine
Toulon A,Breton L,Taylor KR,Tenenhaus M,Bhavsar D,Lanigan C,Rudolph R,Jameson J,Havran WL
14-0038 was used in Flow cytometry/Cell sorting to demonstrate that human epidermal T cells are able to produce IGF-1 upon activation to promote wound healing.
Mon Apr 13 00:00:00 EDT 2009
Hepatitis B virus surface antigen impairs myeloid dendritic cell function: a possible immune escape mechanism of hepatitis B virus.
Immunology
Op den Brouw ML,Binda RS,van Roosmalen MH,Protzer U,Janssen HL,van der Molen RG,Woltman AM
14-0038 was used in Flow cytometry/Cell sorting to assess whether hepatitis B virus directly influences myeloid dendritic cell function.
Sun Feb 01 00:00:00 EST 2009
Loss of the Brm-type SWI/SNF chromatin remodeling complex is a strong barrier to the Tat-independent transcriptional elongation of human immunodeficiency virus type 1 transcripts.
Journal of virology
Mizutani T,Ishizaka A,Tomizawa M,Okazaki T,Yamamichi N,Kawana-Tachikawa A,Iwamoto A,Iba H
14-0038 was used in Functional assays to elucidate the epigenetic regulation of Tat-independent HIV transcription following proviral integration, showing that loss of the Brm-type SWI/SNF chromatin remodeling complex is a strong barrier against elongation.
Sun Nov 01 00:00:00 EDT 2009
Construction and preclinical evaluation of an anti-CD19 chimeric antigen receptor.
Journal of immunotherapy (Hagerstown, Md. : 1997)
Kochenderfer JN,Feldman SA,Zhao Y,Xu H,Black MA,Morgan RA,Wilson WH,Rosenberg SA
14-0038 was used in Flow cytometry/Cell sorting to construct and compare two chimaeric antigen receptors containing a single chain variable region moiety that recognises CD19.
Tue Sep 01 00:00:00 EDT 2009
Expansion of regulatory T cells in patients with Langerhans cell histiocytosis.
PLoS medicine
Senechal B,Elain G,Jeziorski E,Grondin V,Patey-Mariaud de Serre N,Jaubert F,Beldjord K,Lellouch A,Glorion C,Zerah M,Mary P,Barkaoui M,Emile JF,Boccon-Gibod L,Josset P,Debré M,Fischer A,Donadieu J,Geissmann F
Published figure using CD3 monoclonal antibody (Product # 14-0038-82) in Immunohistochemistry
Wed Aug 01 00:00:00 EDT 2007
Bacterial superantigens bypass Lck-dependent T cell receptor signaling by activating a Galpha11-dependent, PLC-beta-mediated pathway.
Immunity
Bueno C,Lemke CD,Criado G,Baroja ML,Ferguson SS,Rahman AK,Tsoukas CD,McCormick JK,Madrenas J
14-0038 was used in Flow cytometry/Cell sorting to show that this alternative pathway operates in the absence of Lck-dependent tyrosine-phosphorylation events and was initiated by the TCR-dependent activation of raft-enriched heterotrimeric Galpha11 proteins.
Sat Jul 01 00:00:00 EDT 2006
Expression of the novel co-stimulatory molecule B7-H4 by renal tubular epithelial cells.
Kidney international
Chen Y,Yang C,Xie Z,Zou L,Ruan Z,Zhang X,Tang Y,Fei L,Jia Z,Wu Y
14-0038 was used in Functional assays to investigate the expression of B7-H4 on cryostat renal biopsies from patients with nephritis.
Fri Dec 01 00:00:00 EST 2006