Product References
Perinatal murine cytomegalovirus infection reshapes the transcriptional profile and functionality of NK cells.
Nature communications
Rožmanić C,Lisnić B,Pribanić Matešić M,Mihalić A,Hiršl L,Park E,Lesac Brizić A,Indenbirken D,Viduka I,Šantić M,Adler B,Yokoyama WM,Krmpotić A,Juranić Lisnić V,Jonjić S,Brizić I
Published figure using CD49b (Integrin alpha 2) monoclonal antibody (Product # 11-5971-82) in Flow Cytometry
Thu Oct 12 00:00:00 EDT 2023
Lenvatinib for effectively treating antiangiogenic drug-resistant nasopharyngeal carcinoma.
Cell death & disease
Sun Q,Wang Y,Ji H,Sun X,Xie S,Chen L,Li S,Zeng W,Chen R,Tang Q,Zuo J,Hou L,Hosaka K,Lu Y,Liu Y,Ye Y,Yang Y
11-5971-82 was used in Flow cytometry/Cell sorting to provide mechanistic insights on FGF-2 signaling in the modulation of VEGF pathway activation in the NPC microenvironment and propose an effective NPC-targeted therapy by using a clinically available drug.
Fri Aug 19 00:00:00 EDT 2022
Hypoxia-mediated stabilization of HIF1A in prostatic intraepithelial neoplasia promotes cell plasticity and malignant progression.
Science advances
Abu El Maaty MA,Terzic J,Keime C,Rovito D,Lutzing R,Yanushko D,Parisotto M,Grelet E,Namer IJ,Lindner V,Laverny G,Metzger D
11-5971-82 was used in Flow cytometry/Cell sorting to characterize prostatic intraepithelial neoplasia (PIN) progression and demonstrate that HIF1A is a target for PCa prevention and that TGM2 is a promising prognostic biomarker of early relapse after prostatectomy.
Fri Jul 22 00:00:00 EDT 2022
Stage-specific action of Runx1 and GATA3 controls silencing of PU.1 expression in mouse pro-T cells.
The Journal of experimental medicine
Hosokawa H,Koizumi M,Masuhara K,Romero-Wolf M,Tanaka T,Nakayama T,Rothenberg EV
Published figure using CD49b (Integrin alpha 2) monoclonal antibody (Product # 11-5971-82) in Flow Cytometry
Mon Aug 02 00:00:00 EDT 2021
Exosomes derived from retinoblastoma cells enhance tumour deterioration by infiltrating the microenvironment.
Oncology reports
Chen S,Chen X,Qiu J,Chen P,Han X,Wu Y,Zhuang J,Yang M,Wu C,Wu N,Yang Y,Ge J,Yu K,Zhuang J
Published figure using CD49b (Integrin alpha 2) monoclonal antibody (Product # 11-5971-82) in Immunohistochemistry
Fri Jan 01 00:00:00 EST 2021
A helminth-derived suppressor of ST2 blocks allergic responses.
eLife
Vacca F,Chauché C,Jamwal A,Hinchy EC,Heieis G,Webster H,Ogunkanbi A,Sekne Z,Gregory WF,Wear M,Perona-Wright G,Higgins MK,Nys JA,Cohen ES,McSorley HJ
11-5971 was used in Flow cytometry/Cell sorting to demonstrate that H. polygyrus blocks the IL-33 pathway via both HpARI which blocks the cytokine, and also HpBARI which blocks the receptor.
Mon May 18 00:00:00 EDT 2020
A Regulatory Circuit Controlling the Dynamics of NFκB cRel Transitions B Cells from Proliferation to Plasma Cell Differentiation.
Immunity
Roy K,Mitchell S,Liu Y,Ohta S,Lin YS,Metzig MO,Nutt SL,Hoffmann A
11-5971-82 was used in Flow Cytometry to provide a mechanistic explanation of how dysregulation of this bi-stable circuit might result in pathologic B cell population phenotypes and thus offer new avenues for diagnostic stratification and treatment.
Tue Mar 19 00:00:00 EDT 2019
Ovalbumin induces natural killer cells to secrete Th2 cytokines IL‑5 and IL‑13 in a mouse model of asthma.
Molecular medicine reports
Chen Z,Wang L
11-5971-82 was used in Flow Cytometry to analyse the dynamic changes of NK cells and their subsets during the development of the ovalbumin (OVA)‚induced allergic airway response.
Mon Apr 01 00:00:00 EDT 2019
Enhanced germinal center reaction by targeting vaccine antigen to major histocompatibility complex class II molecules.
NPJ vaccines
Andersen TK,Huszthy PC,Gopalakrishnan RP,Jacobsen JT,Fauskanger M,Tveita AA,Grødeland G,Bogen B
11-5971 was used in Flow cytometry/Cell sorting to study the underlying mechanism by which the targeting of antigen to MHCII on antigen-presenting cells increases antibody responses.
Thu Oct 05 00:00:00 EDT 2023
A Circular RNA Protects Dormant Hematopoietic Stem Cells from DNA Sensor cGAS-Mediated Exhaustion.
Immunity
Xia P,Wang S,Ye B,Du Y,Li C,Xiong Z,Qu Y,Fan Z
11-5971 was used in Flow cytometry/Cell sorting to study circular RNA-mediated maintenance of hematopoeitic stem cell homeostasis.
Tue Apr 17 00:00:00 EDT 2018
Targeting immune checkpoints potentiates immunoediting and changes the dynamics of tumor evolution.
Nature communications
Efremova M,Rieder D,Klepsch V,Charoentong P,Finotello F,Hackl H,Hermann-Kleiter N,Löwer M,Baier G,Krogsdam A,Trajanoski Z
11-5971 was used in Flow cytometry/Cell sorting to demonstrate that neutral evolution is another force that contributes to sculpting the tumor and that checkpoint blockade effectively enforces T-cell-dependent immunoselective pressure.
Tue Jan 02 00:00:00 EST 2018
Reduction of MHC-I expression limits T-lymphocyte-mediated killing of Cancer-initiating cells.
BMC cancer
Morrison BJ,Steel JC,Morris JC
11-5971 was used in Flow cytometry/Cell sorting to suggest that the attenuated expression of MHC-I molecules by CICs represents a potential strategy of CICs to escape immune recognition, and that the development of successful immunotherapy strategies targeting CICs may decrease their resistance to T cell-mediated immune detection by enhancing CIC MHC-I expression.
Thu Apr 26 00:00:00 EDT 2018
HpARI Protein Secreted by a Helminth Parasite Suppresses Interleukin-33.
Immunity
Osbourn M,Soares DC,Vacca F,Cohen ES,Scott IC,Gregory WF,Smyth DJ,Toivakka M,Kemter AM,le Bihan T,Wear M,Hoving D,Filbey KJ,Hewitson JP,Henderson H,Gonzàlez-Cìscar A,Errington C,Vermeren S,Astier AL,Wallace WA,Schwarze J,Ivens AC,Maizels RM,McSorley HJ
11-5971 was used in an ELISA assay to study how HpARI employs a novel molecular strategy to suppress type 2 immunity in both infection and allergy.
Tue Oct 17 00:00:00 EDT 2017
DC subset-specific induction of T cell responses upon antigen uptake via Fcγ receptors in vivo.
The Journal of experimental medicine
Lehmann CHK,Baranska A,Heidkamp GF,Heger L,Neubert K,Lühr JJ,Hoffmann A,Reimer KC,Brückner C,Beck S,Seeling M,Kießling M,Soulat D,Krug AB,Ravetch JV,Leusen JHW,Nimmerjahn F,Dudziak D
11-5971 was used in Flow cytometry/Cell sorting to suggest that targeting antigens to FcγRs on DCs may be a promising approach to raise immunogenic or tolerogenic T cell responses to antigens of choice.
Mon May 01 00:00:00 EDT 2017
Anti-PD-L1 peptide improves survival in sepsis.
The Journal of surgical research
Shindo Y,McDonough JS,Chang KC,Ramachandra M,Sasikumar PG,Hotchkiss RS
11-5971 was used in Flow cytometry/Cell sorting to assess the efficacy of a novel short-acting peptide that inhibits programmed cell death 1 and its ligand signalling, in a clinically relevant second-hit fungal sepsis model.
Wed Feb 01 00:00:00 EST 2017
Characterisation of innate lymphoid cell populations at different sites in mice with defective T cell immunity.
Wellcome open research
Dutton EE,Camelo A,Sleeman M,Herbst R,Carlesso G,Belz GT,Withers DR
11-5971 was used in Flow cytometry/Cell sorting to compare the innate lymphoid cell populations at different sites in mice with defective T cell immunity.
Sat Jan 09 00:00:00 EST 2021
The breast tumor microenvironment alters the phenotype and function of natural killer cells.
Cellular & molecular immunology
Krneta T,Gillgrass A,Chew M,Ashkar AA
Published figure using CD49b (Integrin alpha 2) monoclonal antibody (Product # 11-5971-82) in Flow Cytometry
Thu Sep 01 00:00:00 EDT 2016
Innate lymphoid cells contribute to allergic airway disease exacerbation by obesity.
The Journal of allergy and clinical immunology
Everaere L,Ait-Yahia S,Molendi-Coste O,Vorng H,Quemener S,LeVu P,Fleury S,Bouchaert E,Fan Y,Duez C,de Nadai P,Staels B,Dombrowicz D,Tsicopoulos A
11-5971 was used in Flow cytometry/Cell sorting to indicate that high-fat diet-induced obesity might exacerbate allergic airway inflammation through mechanisms involving ILC2s and ILC3s.
Tue Nov 01 00:00:00 EDT 2016
Lack of the programmed death-1 receptor renders host susceptible to enteric microbial infection through impairing the production of the mucosal natural killer cell effector molecules.
Journal of leukocyte biology
Solaymani-Mohammadi S,Lakhdari O,Minev I,Shenouda S,Frey BF,Billeskov R,Singer SM,Berzofsky JA,Eckmann L,Kagnoff MF
11-5971 was used in Flow cytometry/Cell sorting to identify the role of the programmed death-1 receptor in early host microbial defence at the intestinal mucosa.
Tue Mar 01 00:00:00 EST 2016
Diacylglycerol Kinase ζ Is a Target To Enhance NK Cell Function.
Journal of immunology (Baltimore, Md. : 1950)
Yang E,Singh BK,Paustian AM,Kambayashi T
11-5971 was used in Flow cytometry/Cell sorting to investigate methods to enhance NK cell function, showing that diacylglycerol kinase ζ is a target for enhancement of NK function.
Mon Aug 01 00:00:00 EDT 2016
Immune adjuvant effect of a Toxoplasma gondii profilin-like protein in autologous whole-tumor-cell vaccination in mice.
Oncotarget
Pyo KH,Lee YW,Lim SM,Shin EH
11-5971 was used in Flow cytometry/Cell sorting to explore the potential of TgPLP as an adjuvant in autologous whole-tumour-cell vaccines.
Tue Nov 08 00:00:00 EST 2016
Interleukin-7 and anti-programmed cell death 1 antibody have differing effects to reverse sepsis-induced immunosuppression.
Shock (Augusta, Ga.)
Shindo Y,Unsinger J,Burnham CA,Green JM,Hotchkiss RS
11-5971 was used in Flow cytometry/Cell sorting to investigate differences in immunomodulatory actions between IL-7 and anti-PD-1, to evaluate their potential use in the therapy of sepsis.
Wed Apr 01 00:00:00 EDT 2015
Interleukin-17-producing innate lymphoid cells and the NLRP3 inflammasome facilitate obesity-associated airway hyperreactivity.
Nature medicine
Kim HY,Lee HJ,Chang YJ,Pichavant M,Shore SA,Fitzgerald KA,Iwakura Y,Israel E,Bolger K,Faul J,DeKruyff RH,Umetsu DT
11-5971 was used in Flow cytometry/Cell sorting to show that IL-17 producing innate lymphoid cells and the NLRP3 inflammasome facilitate obesity-associated airway hyperreactivity.
Wed Jan 01 00:00:00 EST 2014
Asthma increases susceptibility to heterologous but not homologous secondary influenza.
Journal of virology
Furuya Y,Roberts S,Hurteau GJ,Sanfilippo AM,Racine R,Metzger DW
11-5971 was used in Flow cytometry/Cell sorting to show that antibody responses during secondary heterologous influenza infections are suboptimal which causes increased viral infection mortality in asthmatic mice.
Fri Aug 01 00:00:00 EDT 2014
Bronchial epithelial injury in the context of alloimmunity promotes lymphocytic bronchiolitis through hyaluronan expression.
American journal of physiology. Lung cellular and molecular physiology
Stober VP,Szczesniak C,Childress Q,Heise RL,Bortner C,Hollingsworth JW,Neuringer IP,Palmer SM,Garantziotis S
11-5971 was used in Flow cytometry/Cell sorting to study the effect of sterile bronchial epithelial injuries on alloimmunity.
Sun Jun 01 00:00:00 EDT 2014
Long-term prevention of chronic allograft rejection by regulatory T-cell immunotherapy involves host Foxp3-expressing T cells.
Blood
Pasquet L,Douet JY,Sparwasser T,Romagnoli P,van Meerwijk JP
11-5971 was used in Flow cytometry/Cell sorting to assess if persistence of administered regulatory T cells is required for long-term maintenance of tolerance to allografts.
Thu May 23 00:00:00 EDT 2013
Perturbation of NK cell peripheral homeostasis accelerates prostate carcinoma metastasis.
The Journal of clinical investigation
Liu G,Lu S,Wang X,Page ST,Higano CS,Plymate SR,Greenberg NM,Sun S,Li Z,Wu JD
11-5971 was used in Flow cytometry/Cell sorting to provide evidence in vivo that soluble and membrane-restricted NKG2D ligands pose opposite impacts on cancer progression.
Tue Oct 01 00:00:00 EDT 2013
Role of NK cells in host defense against pulmonary type A Francisella tularensis infection.
Microbes and infection
Schmitt DM,O'Dee DM,Brown MJ,Horzempa J,Russo BC,Morel PA,Nau GJ
11-5971 was used in Flow cytometry/Cell sorting to investigate role of NK cells against F.tularensis infection in vivo, with LVS-vaccinated murine hosts.
Fri Mar 01 00:00:00 EST 2013
Evidence for a multipotent mammary progenitor with pregnancy-specific activity.
Breast cancer research : BCR
Kaanta AS,Virtanen C,Selfors LM,Brugge JS,Neel BG
Published figure using CD49b (Integrin alpha 2) monoclonal antibody (Product # 11-5971-82) in Immunofluorescence
Mon Dec 08 00:00:00 EST 2014
Both NK cell-intrinsic and -extrinsic STAT1 signaling are required for NK cell response against vaccinia virus.
Journal of immunology (Baltimore, Md. : 1950)
Fortin C,Huang X,Yang Y
11-5971 was used in Flow cytometry/Cell sorting to explore the role of STAT1 in natural killer cell responses to vaccinia virus infection in vivo.
Mon Jul 01 00:00:00 EDT 2013
Uterine natural killer cells severely decrease in number at gestation day 6 in mice.
Biology of reproduction
Takashima A,Ishikawa F,Kuwabara T,Tanaka Y,Kinoshita T,Ito M,Kakiuchi T
11-5971 was used in Flow cytometry/Cell sorting to study how uterine NK cells or their precursors migrate into the uterus, mature, and produce interferon-gamma to support pregnancy in mice.
Tue Oct 01 00:00:00 EDT 2013
CD36 contributes to malaria parasite-induced pro-inflammatory cytokine production and NK and T cell activation by dendritic cells.
PloS one
Gowda NM,Wu X,Kumar S,Febbraio M,Gowda DC
11-5971 was used in an ELISA assay to imply that the effect of CD36 on malaria immunity is imprinted early during infection when parasite load is low.
Tue Aug 05 00:00:00 EDT 2014
Natural killer cells regulate murine cytomegalovirus-induced sialadenitis and salivary gland disease.
Journal of virology
Carroll VA,Lundgren A,Wei H,Sainz S,Tung KS,Brown MG
11-5971 was used in Flow cytometry/Cell sorting to discover that natural killer cells preserve organ integrity and function and regulate the innate inflammatory response within the salivary gland.
Wed Feb 01 00:00:00 EST 2012
TLR9 and MyD88 are crucial for the development of protective immunity to malaria.
Journal of immunology (Baltimore, Md. : 1950)
Gowda NM,Wu X,Gowda DC
11-5971 was used in Flow cytometry/Cell sorting to investigate TLR9 and MyD88 regulation of pro/anti-inflammatory cytokines in mice infected with Plasmodium yoelii.
Tue May 15 00:00:00 EDT 2012
High susceptibility to lipopolysaccharide-induced lethal shock in encephalomyocarditis virus-infected mice.
Scientific reports
Ohtaki H,Ito H,Hoshi M,Osawa Y,Takamatsu M,Hara A,Ishikawa T,Moriwaki H,Saito K,Seishima M
11-5971 was used in Flow cytometry/Cell sorting to examine and explore the effect of lipopolysaccharide on encephalomyocarditis virus-infected mice.
Fri Apr 12 00:00:00 EDT 2013
Distinct MHC class I-dependent NK cell-activating receptors control cytomegalovirus infection in different mouse strains.
The Journal of experimental medicine
Pyzik M,Charbonneau B,Gendron-Pontbriand EM,Babić M,Krmpotić A,Jonjić S,Vidal SM
11-5971 was used in Flow cytometry/Cell sorting to study how multiple activating Ly49 receptors may participate in H-2-dependent recognition of MCMV infection, providing a common mechanism of NK cell-mediated resistance against viral infection.
Mon May 09 00:00:00 EDT 2011
Anti-tumour synergy of cytotoxic chemotherapy and anti-CD40 plus CpG-ODN immunotherapy through repolarization of tumour-associated macrophages.
Immunology
Buhtoiarov IN,Sondel PM,Wigginton JM,Buhtoiarova TN,Yanke EM,Mahvi DA,Rakhmilevich AL
11-5971-82 was used in Flow Cytometry to show that chemotherapy and anti-CD40 + CpG-ODN IT synergise in the induction of anti-tumour effects which are associated with the phenotypic repolarisation of tumour-associated Mφ.
Tue Feb 01 00:00:00 EST 2011
Vesicular stomatitis virus expressing tumor suppressor p53 is a highly attenuated, potent oncolytic agent.
Journal of virology
Heiber JF,Barber GN
Published figure using CD49b (Integrin alpha 2) monoclonal antibody (Product # 11-5971-82) in Western Blot
Sat Oct 01 00:00:00 EDT 2011
Differential internalization of hu14.18-IL2 immunocytokine by NK and tumor cell: impact on conjugation, cytotoxicity, and targeting.
Journal of leukocyte biology
Buhtoiarov IN,Neal ZC,Gan J,Buhtoiarova TN,Patankar MS,Gubbels JA,Hank JA,Yamane B,Rakhmilevich AL,Reisfeld RA,Gillies SD,Sondel PM
11-5971 was used in Flow cytometry/Cell sorting to demonstrate that once IC binds to the tumour, it is present on the tumour surface for a prolonged time, inducing tumour cell killing.
Fri Apr 01 00:00:00 EDT 2011
FcεRI, but not FcγR, signals induce prostaglandin D2 and E2 production from basophils.
The American journal of pathology
Ugajin T,Satoh T,Kanamori T,Aritake K,Urade Y,Yokozeki H
11-5971-82 was used in Magnetic cell separation to show that basophils function as a source of PGD2 and PGE2.
Mon Aug 01 00:00:00 EDT 2011
Myeloid-derived suppressor cells infiltrate the heart in acute Trypanosoma cruzi infection.
Journal of immunology (Baltimore, Md. : 1950)
Cuervo H,Guerrero NA,Carbajosa S,Beschin A,De Baetselier P,Gironès N,Fresno M
11-5971 was used in Flow cytometry/Cell sorting to purify and characterise the phenotype and function of CD11b(+) myeloid cells from the hearts of Trypanosoma cruzi-infected mice.
Thu Sep 01 00:00:00 EDT 2011
Th-1 lymphocytes induce dendritic cell tumor killing activity by an IFN-γ-dependent mechanism.
Journal of immunology (Baltimore, Md. : 1950)
LaCasse CJ,Janikashvili N,Larmonier CB,Alizadeh D,Hanke N,Kartchner J,Situ E,Centuori S,Har-Noy M,Bonnotte B,Katsanis E,Larmonier N
11-5971 was used in Flow cytometry/Cell sorting to investigate the regulation of murine dendritic cell cytotoxic functions by T lymphocytes.
Thu Dec 15 00:00:00 EST 2011
CpG and non-CpG oligodeoxynucleotides directly costimulate mouse and human CD4+ T cells through a TLR9- and MyD88-independent mechanism.
Journal of immunology (Baltimore, Md. : 1950)
Landrigan A,Wong MT,Utz PJ
11-5971 was used in Flow cytometry/Cell sorting to study the ability of oligodeoxynucleotides to activate and polarise T cells.
Thu Sep 15 00:00:00 EDT 2011
The nucleosome (histone-DNA complex) is the TLR9-specific immunostimulatory component of Plasmodium falciparum that activates DCs.
PloS one
Gowda NM,Wu X,Gowda DC
11-5971 was used in an ELISA assay to provide a significant insight into the activation of DCs by malaria parasites.
Fri Oct 14 00:00:00 EDT 2011
Type I interferon drives dendritic cell apoptosis via multiple BH3-only proteins following activation by PolyIC in vivo.
PloS one
Fuertes Marraco SA,Scott CL,Bouillet P,Ives A,Masina S,Vremec D,Jansen ES,O'Reilly LA,Schneider P,Fasel N,Shortman K,Strasser A,Acha-Orbea H
11-5971 was used in Flow cytometry/Cell sorting to elucidate the possible apoptotic mechanisms that control activated dendritic cell lifespan in response to PAMPs.
Fri Sep 30 00:00:00 EDT 2011
Dose-dependent effect of anti-CTLA-4 on survival in sepsis.
Shock (Augusta, Ga.)
Inoue S,Bo L,Bian J,Unsinger J,Chang K,Hotchkiss RS
11-5971-82 was used in Flow cytometry/Cell sorting to show that anti-CTLA-4 based immunotherapy offers promise in the treatment of sepsis but care must be used in the timing and dose of administration of the drug to prevent adverse effects.
Fri Jul 01 00:00:00 EDT 2011
Ig gene-like molecule CD31 plays a nonredundant role in the regulation of T-cell immunity and tolerance.
Proceedings of the National Academy of Sciences of the United States of America
Ma L,Mauro C,Cornish GH,Chai JG,Coe D,Fu H,Patton D,Okkenhaug K,Franzoso G,Dyson J,Nourshargh S,Marelli-Berg FM
11-5971 was used in Magnetic cell separation to investigate the contribution of CD31 to T-cell responses, showing that it plays a nonredundant role in the regulation of T-cell immunity and tolerance.
Tue Nov 09 00:00:00 EST 2010
Interleukin-22 (IL-22) production by pulmonary Natural Killer cells and the potential role of IL-22 during primary influenza virus infection.
Journal of virology
Guo H,Topham DJ
11-5971 was used in Flow cytometry/Cell sorting to test whether interleukin-22 (IL-22) is protective during influenza virus infection, showing that IL-22 plays a marginal role for protection, with a differential requirement of this cytokine for bacterial and viral infections.
Sun Aug 01 00:00:00 EDT 2010
Delayed administration of anti-PD-1 antibody reverses immune dysfunction and improves survival during sepsis.
Journal of leukocyte biology
Brahmamdam P,Inoue S,Unsinger J,Chang KC,McDunn JE,Hotchkiss RS
Sun Aug 01 00:00:00 EDT 2010
Virulence of Toxoplasma gondii is associated with distinct dendritic cell responses and reduced numbers of activated CD8+ T cells.
Journal of immunology (Baltimore, Md. : 1950)
Tait ED,Jordan KA,Dupont CD,Harris TH,Gregg B,Wilson EH,Pepper M,Dzierszinski F,Roos DS,Hunter CA
11-5971 was used in Flow cytometry/Cell sorting to show the dendritic cell response to T.gondii alters levels of CD8+ T cells which ultimately determine the outcome of infection.
Sun Aug 01 00:00:00 EDT 2010
IL-15 prevents apoptosis, reverses innate and adaptive immune dysfunction, and improves survival in sepsis.
Journal of immunology (Baltimore, Md. : 1950)
Inoue S,Unsinger J,Davis CG,Muenzer JT,Ferguson TA,Chang K,Osborne DF,Clark AT,Coopersmith CM,McDunn JE,Hotchkiss RS
11-5971 was used in Flow cytometry/Cell sorting to assess the use of IL-15 as a potential therapy for sepsis.
Mon Feb 01 00:00:00 EST 2010
Intracellular staining for analysis of the expression and phosphorylation of signal transducers and activators of transcription (STATs) in NK cells.
Methods in molecular biology (Clifton, N.J.)
Miyagi T,Lee SH,Biron CA
11-5971 was used in Flow cytometry/Cell sorting to develop approaches to measure the levels of expression and activation of signalling molecules.
Fri Feb 26 00:00:00 EST 2010
Basophils preferentially express mouse Mast Cell Protease 11 among the mast cell tryptase family in contrast to mast cells.
Journal of leukocyte biology
Ugajin T,Kojima T,Mukai K,Obata K,Kawano Y,Minegishi Y,Eishi Y,Yokozeki H,Karasuyama H
11-5971 was used in Flow cytometry/Cell sorting to reveal mouse basophils rather than mast cells are the major source of mMCP-11, a trypsin-like protease.
Tue Dec 01 00:00:00 EST 2009
Hypercostimulation through 4-1BB distorts homeostasis of immune cells.
Journal of immunology (Baltimore, Md. : 1950)
Lee SW,Salek-Ardakani S,Mittler RS,Croft M
11-5971 was used in Immunohistochemistry-immunofluorescence to investigate the potential side effects of immunotherapeutic strategies using Abs against costimulatory molecules.
Mon Jun 01 00:00:00 EDT 2009
Locally administered TLR7 agonists drive systemic antitumor immune responses that are enhanced by anti-CD40 immunotherapy.
Journal of immunology (Baltimore, Md. : 1950)
Broomfield SA,van der Most RG,Prosser AC,Mahendran S,Tovey MG,Smyth MJ,Robinson BW,Currie AJ
11-5971 was used in Flow cytometry/Cell sorting to show that locally delivered TLR7 agonist imiquimod in conjuction with systemic anti-CD40 immunotherapy significantly enhances the local antitumor response and retards growth of distal tumors.
Fri May 01 00:00:00 EDT 2009
Basophils play a pivotal role in immunoglobulin-G-mediated but not immunoglobulin-E-mediated systemic anaphylaxis.
Immunity
Tsujimura Y,Obata K,Mukai K,Shindou H,Yoshida M,Nishikado H,Kawano Y,Minegishi Y,Shimizu T,Karasuyama H
11-5971 was used in Flow cytometry/Cell sorting to highlight a pivotal role for basophils in vivo and contrast two major, distinct pathways leading to allergen-induced systemic anaphylaxis.
Tue Apr 01 00:00:00 EDT 2008
Overexpression of indoleamine 2,3-dioxygenase in human endometrial carcinoma cells induces rapid tumor growth in a mouse xenograft model.
Clinical cancer research : an official journal of the American Association for Cancer Research
Yoshida N,Ino K,Ishida Y,Kajiyama H,Yamamoto E,Shibata K,Terauchi M,Nawa A,Akimoto H,Takikawa O,Isobe K,Kikkawa F
11-5971 was used in Flow cytometry/Cell sorting to clarify the functional role of indoleamine 2,3-dioxygenase (IDO) in human endometrial cancer cells, and investigate the therapeutic potential of IDO inhibitors.
Sat Nov 15 00:00:00 EST 2008
Unique receptor repertoire in mouse uterine NK cells.
Journal of immunology (Baltimore, Md. : 1950)
Yadi H,Burke S,Madeja Z,Hemberger M,Moffett A,Colucci F
11-5971-82 was used in Flow Cytometry to define the receptor repertoire and phenotype of uterine NK cells at mid-gestation in mice.
Sat Nov 01 00:00:00 EDT 2008
