Product References
Cathepsin S inhibition in dendritic cells prevents Th17 cell differentiation in perivascular adipose tissues following vascular injury in diabetic rats.
Journal of biochemical and molecular toxicology
Peng H,Lv Y,Li C,Cheng Z,He S,Wang C,Liu J
Published figure using CD4 monoclonal antibody (Product # 12-0049-42) in Flow Cytometry
Fri Sep 01 00:00:00 EDT 2023
Rapamycin improves Graves' orbitopathy by suppressing CD4+ cytotoxic T lymphocytes.
JCI insight
Zhang M,Chong KK,Chen ZY,Guo H,Liu YF,Kang YY,Li YJ,Shi TT,Lai KK,He MQ,Ye K,Kahaly GJ,Shi BY,Wang Y
Published figure using CD4 monoclonal antibody (Product # 12-0049-42) in Flow Cytometry
Wed Feb 08 00:00:00 EST 2023
HERC2 promotes inflammation-driven cancer stemness and immune evasion in hepatocellular carcinoma by activating STAT3 pathway.
Journal of experimental & clinical cancer research : CR
Liu Y,Xu Q,Deng F,Zheng Z,Luo J,Wang P,Zhou J,Lu X,Zhang L,Chen Z,Zhang Q,Chen Q,Zuo D
12-0049-42 was used in Flow cytometry/Cell sorting to identify HERC2 functions as a previously unknown modulator of the JAK2/STAT3 pathway, thereby promoting inflammation-induced stemness and immune evasion in HCC.
Wed Feb 01 00:00:00 EST 2023
Single-cell RNA sequencing reveals the molecular features of peripheral blood immune cells in children, adults and centenarians.
Frontiers in immunology
Zhong J,Ding R,Jiang H,Li L,Wan J,Feng X,Chen M,Peng L,Li X,Lin J,Yang H,Wang M,Li Q,Chen Q
Published figure using CD4 monoclonal antibody (Product # 12-0049-42) in Flow Cytometry
Mon Jan 30 00:00:00 EST 2023
Single-cell profiling of healthy human kidney reveals features of sex-based transcriptional programs and tissue-specific immunity.
Nature communications
McEvoy CM,Murphy JM,Zhang L,Clotet-Freixas S,Mathews JA,An J,Karimzadeh M,Pouyabahar D,Su S,Zaslaver O,Röst H,Arambewela R,Liu LY,Zhang S,Lawson KA,Finelli A,Wang B,MacParland SA,Bader GD,Konvalinka A,Crome SQ
Published figure using CD4 monoclonal antibody (Product # 12-0049-42) in Flow Cytometry
Sat Dec 10 00:00:00 EST 2022
Decoding the pathogenesis of Diamond-Blackfan anemia using single-cell RNA-seq.
Cell discovery
Wang B,Wang C,Wan Y,Gao J,Ma Y,Zhang Y,Tong J,Zhang Y,Liu J,Chang L,Xu C,Shen B,Chen Y,Jiang E,Kurita R,Nakamura Y,Lim KC,Engel JD,Zhou J,Cheng T,Zhu X,Zhu P,Shi L
Published figure using CD4 monoclonal antibody (Product # 12-0049-42) in Flow Cytometry
Tue May 10 00:00:00 EDT 2022
c-Met specific CAR-T cells as a targeted therapy for non-small cell lung cancer cell A549.
Bioengineered
Min J,Long C,Zhang L,Duan J,Fan H,Chu F,Li Z
12-0049-42 was used in Flow cytometry/Cell sorting to generate c-Met CAR- T cells, which exhibit enhanced cytotoxicity against NSCLC cells in vitro and in vivo.
Fri Apr 01 00:00:00 EDT 2022
B cells imprint adoptively transferred CD8+ T cells with enhanced tumor immunity.
Journal for immunotherapy of cancer
Smith AS,Knochelmann HM,Wyatt MM,Rangel Rivera GO,Rivera-Reyes AM,Dwyer CJ,Ware MB,Cole AC,Neskey DM,Rubinstein MP,Liu B,Thaxton JE,Bartee E,Paulos CM
12-0049-42 was used in Flow cytometry/Cell sorting to investigate how tumor-specific murine CD8+ T cells and human tumor infiltrating lymphocytes (TILs) are impacted when expanded ex vivo with the TLR9 agonist CpG.
Sat Jan 01 00:00:00 EST 2022
Endothelial dysfunction markers and immune response indices in cosmonauts' blood after long-duration space flights.
NPJ microgravity
Kuzichkin DS,Nichiporuk IA,Zhuravleva OA,Markin AA,Rykova MP,Zhuravleva TV,Sadova AA,Kutko OV,Shmarov VA,Ponomarev SA
12-0049-42 was used in Flow cytometry/Cell sorting to investigat the markers of endothelial activation and damage (plasma concentrations of soluble thrombomodulin fraction (sTM), von Willebrand factor (vWF), highly sensitive C-reactive protein (hs-CRP)), as well as the level of D-dimer and compared them to the immunological parameters characterizing the state of human humoral and cellular immunity.
Wed Nov 02 00:00:00 EDT 2022
Effects of the Antidiabetic Drugs Evogliptin and Sitagliptin on the Immune Function of CD26/DPP4 in Th1 Cells.
Biomolecules & therapeutics
Yoon H,Sung JH,Song MJ
Published figure using CD4 monoclonal antibody (Product # 12-0049-42) in Flow Cytometry
Mon Mar 01 00:00:00 EST 2021
Murlentamab, a Low Fucosylated Anti-Müllerian Hormone Type II Receptor (AMHRII) Antibody, Exhibits Anti-Tumor Activity through Tumor-Associated Macrophage Reprogrammation and T Cell Activation.
Cancers
Prat M,Salon M,Allain T,Dubreuil O,Noël G,Preisser L,Jean B,Cassard L,Lemée F,Tabah-Fish I,Pipy B,Jeannin P,Prost JF,Barret JM,Coste A
Published figure using CD4 monoclonal antibody (Product # 12-0049-42) in Flow Cytometry
Tue Apr 13 00:00:00 EDT 2021
Generation of hypoxia-sensing chimeric antigen receptor T cells.
STAR protocols
Kosti P,Larios-Martinez KI,Maher J,Arnold JN
12-0049-42 was used in Flow Cytometry to summarize the synthetic biology underlying the development of a stringent oxygen-sensitive CAR for in vitro and in vivo preclinical characterization.
Fri Sep 17 00:00:00 EDT 2021
Characterization and modulation of anti-αβTCR antibodies and their respective binding sites at the βTCR chain to enrich engineered T cells.
Molecular therapy. Methods & clinical development
Kierkels GJJ,van Diest E,Hernández-López P,Scheper W,de Bruin ACM,Frijlink E,Aarts-Riemens T,van Dooremalen SFJ,Beringer DX,Oostvogels R,Kramer L,Straetemans T,Uckert W,Sebestyén Z,Kuball J
Published figure using CD4 monoclonal antibody (Product # 12-0049-42) in Flow Cytometry
Fri Sep 10 00:00:00 EDT 2021
Bispecific T-Cell Engaging Antibodies Against MUC16 Demonstrate Efficacy Against Ovarian Cancer in Monotherapy and in Combination With PD-1 and VEGF Inhibition.
Frontiers in immunology
Yeku OO,Rao TD,Laster I,Kononenko A,Purdon TJ,Wang P,Cui Z,Liu H,Brentjens RJ,Spriggs D
Published figure using CD4 monoclonal antibody (Product # 12-0049-42) in Flow Cytometry
Thu Oct 21 00:00:00 EDT 2021
Bispecific T-Cell Engaging Antibodies Against MUC16 Demonstrate Efficacy Against Ovarian Cancer in Monotherapy and in Combination With PD-1 and VEGF Inhibition.
Frontiers in immunology
Yeku OO,Rao TD,Laster I,Kononenko A,Purdon TJ,Wang P,Cui Z,Liu H,Brentjens RJ,Spriggs D
Published figure using CD4 monoclonal antibody (Product # 12-0049-42) in Flow Cytometry
Thu Oct 21 00:00:00 EDT 2021
Hypoxia-sensing CAR T cells provide safety and efficacy in treating solid tumors.
Cell reports. Medicine
Kosti P,Opzoomer JW,Larios-Martinez KI,Henley-Smith R,Scudamore CL,Okesola M,Taher MYM,Davies DM,Muliaditan T,Larcombe-Young D,Woodman N,Gillett CE,Thavaraj S,Maher J,Arnold JN
12-0049-42 was used in Flow Cytometry to present a stringent hypoxia-sensing CAR T cell system that achieves selective expression of a pan-ErbB-targeted CAR within a solid tumor.
Tue Apr 20 00:00:00 EDT 2021
Identification of two HLA-A*0201 immunogenic epitopes of lactate dehydrogenase C (LDHC): potential novel targets for cancer immunotherapy.
Cancer immunology, immunotherapy : CII
Thomas R,Shaath H,Naik A,Toor SM,Elkord E,Decock J
Published figure using CD4 monoclonal antibody (Product # 12-0049-42) in Flow Cytometry
Sun Mar 01 00:00:00 EST 2020
HDAC Inhibitor, CG-745, Enhances the Anti-Cancer Effect of Anti-PD-1 Immune Checkpoint Inhibitor by Modulation of the Immune Microenvironment.
Journal of Cancer
Kim YD,Park SM,Ha HC,Lee AR,Won H,Cha H,Cho S,Cho JM
12-0049 was used in Flow cytometry/Cell sorting to study the HDAC inhibitor CG-745 and its function to enable the synergistic effects of the immune checkpoint inhibitor combination therapy in various cancers by suppressing tumor microenvironment.
Mon Sep 28 00:00:00 EDT 2020
HDAC Inhibitor, CG-745, Enhances the Anti-Cancer Effect of Anti-PD-1 Immune Checkpoint Inhibitor by Modulation of the Immune Microenvironment.
Journal of Cancer
Kim YD,Park SM,Ha HC,Lee AR,Won H,Cha H,Cho S,Cho JM
12-0049 was used in Flow cytometry/Cell sorting to study the HDAC inhibitor CG-745 and its function to enable the synergistic effects of the immune checkpoint inhibitor combination therapy in various cancers by suppressing tumor microenvironment.
Mon Sep 28 00:00:00 EDT 2020
Involvement of natural killer cells in the pathogenesis of endometriosis in patients with pelvic pain.
The Journal of international medical research
He J,Xu Y,Yi M,Gu C,Zhu Y,Hu G
Published figure using CD4 monoclonal antibody (Product # 12-0049-42) in Flow Cytometry
Wed Jul 01 00:00:00 EDT 2020
Standardized 11-color flow cytometry panel for the functional phenotyping of human T regulatory cells.
Journal of biological methods
Manuszak C,Brainard M,Thrash E,Hodi FS,Severgnini M
Published figure using CD4 monoclonal antibody (Product # 12-0049-42) in Flow Cytometry
Mon Sep 28 00:00:00 EDT 2020
MicroRNA‑155 inhibits the proliferation of CD8+ T cells via upregulating regulatory T cells in vitiligo.
Molecular medicine reports
Lv M,Li Z,Liu J,Lin F,Zhang Q,Li Z,Wang Y,Wang K,Xu Y
Published figure using CD4 monoclonal antibody (Product # 12-0049-42) in Flow Cytometry
Tue Oct 01 00:00:00 EDT 2019
RAB11FIP5 Expression and Altered Natural Killer Cell Function Are Associated with Induction of HIV Broadly Neutralizing Antibody Responses.
Cell
Bradley T,Peppa D,Pedroza-Pacheco I,Li D,Cain DW,Henao R,Venkat V,Hora B,Chen Y,Vandergrift NA,Overman RG,Edwards RW,Woods CW,Tomaras GD,Ferrari G,Ginsburg GS,Connors M,Cohen MS,Moody MA,Borrow P,Haynes BF
Published figure using CD4 monoclonal antibody (Product # 12-0049-42) in Flow Cytometry
Thu Oct 04 00:00:00 EDT 2018
The Effects of High Mobility Group Box-1 Protein on Peripheral Treg/Th17 Balance in Patients with Atherosclerosis.
Acta Cardiologica Sinica
Ding JW,Zhou T,Zheng XX,Wang XA,Tong XH,Luo CY,Zhang ZQ,Yu B
Published figure using CD4 monoclonal antibody (Product # 12-0049-42) in Flow Cytometry
Sat Sep 01 00:00:00 EDT 2018
Non-neutralizing Antibodies Alter the Course of HIV-1 Infection In Vivo.
Cell
Horwitz JA,Bar-On Y,Lu CL,Fera D,Lockhart AAK,Lorenzi JCC,Nogueira L,Golijanin J,Scheid JF,Seaman MS,Gazumyan A,Zolla-Pazner S,Nussenzweig MC
Published figure using CD4 monoclonal antibody (Product # 12-0049-42) in Flow Cytometry
Thu Aug 10 00:00:00 EDT 2017
Spontaneous Chitin Accumulation in Airways and Age-Related Fibrotic Lung Disease.
Cell
Van Dyken SJ,Liang HE,Naikawadi RP,Woodruff PG,Wolters PJ,Erle DJ,Locksley RM
12-0049 was used in Flow cytometry/Cell sorting to show that altered chitin clearance could exacerbate fibrogenic pathways in the setting of lung diseases characterised by epithelial cell dysfunction.
Thu Apr 20 00:00:00 EDT 2017
Blocking the recruitment of naive CD4+ T cells reverses immunosuppression in breast cancer.
Cell research
Su S,Liao J,Liu J,Huang D,He C,Chen F,Yang L,Wu W,Chen J,Lin L,Zeng Y,Ouyang N,Cui X,Yao H,Su F,Huang JD,Lieberman J,Liu Q,Song E
Published figure using CD4 monoclonal antibody (Product # 12-0049-42) in Flow Cytometry
Sat Apr 01 00:00:00 EDT 2017
Impact of Enhancer of Zeste Homolog 2 on T Helper Cell-Mediated Allergic Rhinitis.
Frontiers in immunology
Hou TY,Chen MR,Chou YC,Kan PC,Tsai YT,Cha TL
Published figure using CD4 monoclonal antibody (Product # 12-0049-42) in Flow Cytometry
Wed Nov 20 00:00:00 EST 2019
Protein kinase CK2 controls T-cell polarization through dendritic cell activation in response to contact sensitizers.
Journal of leukocyte biology
de Bourayne M,Gallais Y,El Ali Z,Rousseau P,Damiens MH,Cochet C,Filhol O,Chollet-Martin S,Pallardy M,Kerdine-Römer S
Published figure using CD4 monoclonal antibody (Product # 12-0049-42) in Flow Cytometry
Wed Mar 01 00:00:00 EST 2017
CXCL13-producing TFH cells link immune suppression and adaptive memory in human breast cancer.
JCI insight
Gu-Trantien C,Migliori E,Buisseret L,de Wind A,Brohée S,Garaud S,Noël G,Dang Chi VL,Lodewyckx JN,Naveaux C,Duvillier H,Goriely S,Larsimont D,Willard-Gallo K
Published figure using CD4 monoclonal antibody (Product # 12-0049-42) in Flow Cytometry
Fri Jun 02 00:00:00 EDT 2017
Single-cell tracking of flavivirus RNA uncovers species-specific interactions with the immune system dictating disease outcome.
Nature communications
Douam F,Hrebikova G,Albrecht YE,Sellau J,Sharon Y,Ding Q,Ploss A
12-0049 was used in Flow cytometry/Cell sorting to demonstrate the tracking of and sense viral RNA at single-cell resolution within complex subsets of the human and murine immune system in different mouse models.
Tue Mar 14 00:00:00 EDT 2017
Remarkably low affinity of CD4/peptide-major histocompatibility complex class II protein interactions.
Proceedings of the National Academy of Sciences of the United States of America
Jönsson P,Southcombe JH,Santos AM,Huo J,Fernandes RA,McColl J,Lever M,Evans EJ,Hudson A,Chang VT,Hanke T,Godkin A,Dunne PD,Horrocks MH,Palayret M,Screaton GR,Petersen J,Rossjohn J,Fugger L,Dushek O,Xu XN,Davis SJ,Klenerman D
Published figure using CD4 monoclonal antibody (Product # 12-0049-42) in Flow Cytometry
Tue May 17 00:00:00 EDT 2016
New mouse model of acute adult T-cell leukemia generated by transplantation of AKT, BCLxL, and HBZ-transduced T cells.
Cancer science
Kasugai Y,Yoshida N,Ohshima K,Matsuo K,Seto M,Tsuzuki S
12-0049 was used in Flow cytometry/Cell sorting to develop methods to explore the role of candidate genes with the HBZ gene in adult T-cell leukemia/lymphoma development, producing a new mouse model.
Mon Aug 01 00:00:00 EDT 2016
Interaction among activated lymphocytes and mesenchymal cells through podoplanin is critical for a high IL-17 secretion.
Arthritis research & therapy
Noack M,Ndongo-Thiam N,Miossec P
Published figure using CD4 monoclonal antibody (Product # 12-0049-42) in Flow Cytometry
Thu Jun 23 00:00:00 EDT 2016
CD28 family of receptors on T cells in chronic HBV infection: Expression characteristics, clinical significance and correlations with PD-1 blockade.
Molecular medicine reports
Tang ZS,Hao YH,Zhang EJ,Xu CL,Zhou Y,Zheng X,Yang DL
12-0049 was used in Flow cytometry/Cell sorting to investigate the expression characteristics and clinical significance of CD28, PD-1, CTLA4 and BTLA on T-cells in patients with chronic HBV and the correlations among these receptors.
Mon Aug 01 00:00:00 EDT 2016
Interleukin‑33‑induced immune tolerance is associated with the imbalance of memory and naïve T‑lymphocyte subsets.
Molecular medicine reports
Shi X,Tang Y,Sun X,Liu Y,Sun Y,Sun M,Jiang Y,Li Y
12-0049-42 was used in Flow cytometry/Cell sorting to investigate the distribution of memory and naïve T cells in hepatitis B virus‚infected patients at different immune stages, and the effect of interleukin-33 on the regulation of the T‚cell subsets.
Tue Nov 01 00:00:00 EDT 2016
Equilibrium of Treg/Th17 cells of peripheral blood in syphilitic patients with sero-resistance.
Experimental and therapeutic medicine
Zhao J,Ma J,Zhang X,Li Q,Yang X
Published figure using CD4 monoclonal antibody (Product # 12-0049-42) in Flow Cytometry
Wed Jun 01 00:00:00 EDT 2016
Tuning of AKT-pathway by Nef and its blockade by protease inhibitors results in limited recovery in latently HIV infected T-cell line.
Scientific reports
Kumar A,Abbas W,Colin L,Khan KA,Bouchat S,Varin A,Larbi A,Gatot JS,Kabeya K,Vanhulle C,Delacourt N,Pasquereau S,Coquard L,Borch A,König R,Clumeck N,De Wit S,Rohr O,Rouzioux C,Fulop T,Van Lint C,Herbein G
Published figure using CD4 monoclonal antibody (Product # 12-0049-42) in Flow Cytometry
Thu Apr 14 00:00:00 EDT 2016
Lack of T Cell Response to iPSC-Derived Retinal Pigment Epithelial Cells from HLA Homozygous Donors.
Stem cell reports
Sugita S,Iwasaki Y,Makabe K,Kimura T,Futagami T,Suegami S,Takahashi M
Published figure using CD4 monoclonal antibody (Product # 12-0049-42) in Flow Cytometry
Tue Oct 11 00:00:00 EDT 2016
An oncofetal antigen, IMP-3-derived long peptides induce immune responses of both helper T cells and CTLs.
Oncoimmunology
Hirayama M,Tomita Y,Yuno A,Tsukamoto H,Senju S,Imamura Y,Sayem MA,Irie A,Yoshitake Y,Fukuma D,Shinohara M,Hamada A,Jono H,Yuba E,Kono K,Yoshida K,Tsunoda T,Nakayama H,Nishimura Y
12-0049 was used in Flow cytometry/Cell sorting to investigate the potential usefulness of IMP-3-LPs in propagating both Th cells and CTLs.
Wed Jun 01 00:00:00 EDT 2016
RNAi-Mediated CCR5 Knockdown Provides HIV-1 Resistance to Memory T Cells in Humanized BLT Mice.
Molecular therapy. Nucleic acids
Shimizu S,Ringpis GE,Marsden MD,Cortado RV,Wilhalme HM,Elashoff D,Zack JA,Chen IS,An DS
12-0049 was used in Flow cytometry/Cell sorting to demonstrate the potential for effective resistance of sh1005-modified CD4+ T cells to HIV-1 in humanised mice.
Tue Feb 17 00:00:00 EST 2015
Liposomal Glutathione Supplementation Restores TH1 Cytokine Response to Mycobacterium tuberculosis Infection in HIV-Infected Individuals.
Journal of interferon & cytokine research : the official journal of the International Society for Interferon and Cytokine Research
Ly J,Lagman M,Saing T,Singh MK,Tudela EV,Morris D,Anderson J,Daliva J,Ochoa C,Patel N,Pearce D,Venketaraman V
Published figure using CD4 monoclonal antibody (Product # 12-0049-42) in Flow Cytometry
Sun Nov 01 00:00:00 EDT 2015
Distinct patterns of intratumoral immune cell infiltrates in patients with HPV-associated compared to non-virally induced head and neck squamous cell carcinoma.
Oncoimmunology
Partlová S,Bouček J,Kloudová K,Lukešová E,Zábrodský M,Grega M,Fučíková J,Truxová I,Tachezy R,Špíšek R,Fialová A
Published figure using CD4 monoclonal antibody (Product # 12-0049-42) in Flow Cytometry
Thu Jan 01 00:00:00 EST 2015
dNP2 is a blood-brain barrier-permeable peptide enabling ctCTLA-4 protein delivery to ameliorate experimental autoimmune encephalomyelitis.
Nature communications
Lim S,Kim WJ,Kim YH,Lee S,Koo JH,Lee JA,Yoon H,Kim DH,Park HJ,Kim HM,Lee HG,Yun Kim J,Lee JU,Hun Shin J,Kyun Kim L,Doh J,Kim H,Lee SK,Bothwell ALM,Suh M,Choi JM
Published figure using CD4 monoclonal antibody (Product # 12-0049-42) in Flow Cytometry
Tue Sep 15 00:00:00 EDT 2015
Investigating the causes for decreased levels of glutathione in individuals with type II diabetes.
PloS one
Lagman M,Ly J,Saing T,Kaur Singh M,Vera Tudela E,Morris D,Chi PT,Ochoa C,Sathananthan A,Venketaraman V
Published figure using CD4 monoclonal antibody (Product # 12-0049-42) in Flow Cytometry
Wed Dec 30 00:00:00 EST 2015
Immune response to JC virus T antigen in patients with and without colorectal neoplasia.
Gut microbes
Butcher LD,Garcia M,Arnold M,Ueno H,Goel A,Boland CR
Published figure using CD4 monoclonal antibody (Product # 12-0049-42) in Flow Cytometry
Tue Jul 01 00:00:00 EDT 2014
Comparison of human adipose-derived stem cells isolated from subcutaneous, omental, and intrathoracic adipose tissue depots for regenerative applications.
Stem cells translational medicine
Russo V,Yu C,Belliveau P,Hamilton A,Flynn LE
12-0049 was used in Flow cytometry/Cell sorting to determine that depot selection is an important factor to consider when applying ASCs in tissue-specific cell-based regenerative therapies.
Sat Feb 01 00:00:00 EST 2014
Human mesenchymal stromal cells transiently increase cytokine production by activated T cells before suppressing T-cell proliferation: effect of interferon-γ and tumor necrosis factor-α stimulation.
Cytotherapy
Cuerquis J,Romieu-Mourez R,François M,Routy JP,Young YK,Zhao J,Eliopoulos N
12-0049 was used in Flow cytometry/Cell sorting to assess the kinetic effects of mesenchymal stromal cells on cytokine production and T-cell proliferation, cell cycle and apoptosis.
Sat Feb 01 00:00:00 EST 2014
M-CSF inhibits anti-HIV-1 activity of IL-32, but they enhance M2-like phenotypes of macrophages.
Journal of immunology (Baltimore, Md. : 1950)
Osman A,Bhuyan F,Hashimoto M,Nasser H,Maekawa T,Suzu S
12-0049 was used in Flow cytometry/Cell sorting to investigate the functional interplay between M-CSF and IL-32 acting on macrophages.
Sun Jun 01 00:00:00 EDT 2014
OMIP-022: Comprehensive assessment of antigen-specific human T-cell functionality and memory.
Cytometry. Part A : the journal of the International Society for Analytical Cytology
Graves AJ,Padilla MG,Hokey DA
Published figure using CD4 monoclonal antibody (Product # 12-0049-42) in Flow Cytometry
Tue Jul 01 00:00:00 EDT 2014
T helper cell subsets specific for Pseudomonas aeruginosa in healthy individuals and patients with cystic fibrosis.
PloS one
Bayes HK,Bicknell S,MacGregor G,Evans TJ
12-0049 was used in Flow cytometry/Cell sorting to compare the T helper cells resonses to Pseudomonas aeruginosa infection in both healthy and cystic-fibrosis suffering individuals.
Wed Oct 29 00:00:00 EDT 2014
Human regulatory T cells kill tumor cells through granzyme-dependent cytotoxicity upon retargeting with a bispecific antibody.
Cancer immunology research
Choi BD,Gedeon PC,Herndon JE,Archer GE,Reap EA,Sanchez-Perez L,Mitchell DA,Bigner DD,Sampson JH
Published figure using CD4 monoclonal antibody (Product # 12-0049-42) in Flow Cytometry
Sun Sep 01 00:00:00 EDT 2013
Gelsolin activity controls efficient early HIV-1 infection.
Retrovirology
García-Expósito L,Ziglio S,Barroso-González J,de Armas-Rillo L,Valera MS,Zipeto D,Machado JD,Valenzuela-Fernández A
12-0049 was used in Neutralization experiments to propose that gelsolin can limit HIV-1 infection at a pre-fusion step.
Wed Apr 10 00:00:00 EDT 2013
The lantibiotic peptide labyrinthopeptin A1 demonstrates broad anti-HIV and anti-HSV activity with potential for microbicidal applications.
PloS one
Férir G,Petrova MI,Andrei G,Huskens D,Hoorelbeke B,Snoeck R,Vanderleyden J,Balzarini J,Bartoschek S,Brönstrup M,Süssmuth RD,Schols D
12-0049 was used in Functional assays to evaluate the broad-spectrum activity of lantibiotic peptide labyrinthopeptin A1 against HIV and HSV in vitro, its mechanism of action and potential microbicidal applications.
Fri Jan 10 00:00:00 EST 2014
Increased frequencies of Th22 cells as well as Th17 cells in the peripheral blood of patients with ankylosing spondylitis and rheumatoid arthritis.
PloS one
Zhang L,Li YG,Li YH,Qi L,Liu XG,Yuan CZ,Hu NW,Ma DX,Li ZF,Yang Q,Li W,Li JM
Published figure using CD4 monoclonal antibody (Product # 12-0049-42) in Flow Cytometry
Fri Jul 27 00:00:00 EDT 2012
Divergent expression patterns of IL-4 and IL-13 define unique functions in allergic immunity.
Nature immunology
Liang HE,Reinhardt RL,Bando JK,Sullivan BM,Ho IC,Locksley RM
12-0049 was used in Flow cytometry/Cell sorting to assess the temporal and spatial production of IL-4 and IL-13 in vivo.
Sun Dec 04 00:00:00 EST 2011
Upregulation of programmed death-1 on T cells and programmed death ligand-1 on monocytes in septic shock patients.
Critical care (London, England)
Zhang Y,Li J,Lou J,Zhou Y,Bo L,Zhu J,Zhu K,Wan X,Cai Z,Deng X
12-0049 was used in Flow cytometry/Cell sorting to demonstrate that lymphocyte apoptosis is markedly increased in septic shock patients, and suggest an essential role for the PD-1/PD-L1 pathway in sepsis-induced immunosuppression.
Wed Dec 07 00:00:00 EST 2011
Modulation of CD4+ T lymphocyte lineage outcomes with targeted, nanoparticle-mediated cytokine delivery.
Molecular pharmaceutics
Park J,Gao W,Whiston R,Strom TB,Metcalfe S,Fahmy TM
Published figure using CD4 monoclonal antibody (Product # 12-0049-42) in Flow Cytometry
Mon Feb 07 00:00:00 EST 2011
Forced expression of cyclin-dependent kinase 6 confers resistance of pro-B acute lymphocytic leukemia to Gleevec treatment.
Molecular and cellular biology
Kuo TC,Chavarria-Smith JE,Huang D,Schlissel MS
12-0049 was used in Flow cytometry/Cell sorting to find that forced expression of Cdk6 promotes continued cell division and decreased Gleevec-induced apoptosis of leukaemic cells.
Fri Jul 01 00:00:00 EDT 2011
Inhibition of HIV-1 infection by a unique short hairpin RNA to chemokine receptor 5 delivered into macrophages through hematopoietic progenitor cell transduction.
The journal of gene medicine
Liang M,Kamata M,Chen KN,Pariente N,An DS,Chen IS
12-0049 was used in Flow cytometry/Cell sorting to assess the activity of the short hairpin RNA through haematopoietic progenitor cell (HPC) transduction and differentiation into macrophages derived from foetal liver CD34+ HPCs.
Mon Mar 01 00:00:00 EST 2010
Human immunodeficiency virus type 1 escape from cyclotriazadisulfonamide-induced CD4-targeted entry inhibition is associated with increased neutralizing antibody susceptibility.
Journal of virology
Vermeire K,Van Laethem K,Janssens W,Bell TW,Schols D
12-0049-42 was used in Flow Cytometry to study the association between cyclotriazadisulfonamide-resistance in human immunodeficiency virus type 1 and increased susceptibility to neutralising antibodies.
Tue Sep 01 00:00:00 EDT 2009
Sepsis-induced human lymphocyte apoptosis and cytokine production in "humanized" mice.
Journal of leukocyte biology
Unsinger J,McDonough JS,Shultz LD,Ferguson TA,Hotchkiss RS
Published figure using CD4 monoclonal antibody (Product # 12-0049-42) in Flow Cytometry
Sat Aug 01 00:00:00 EDT 2009
B cells and monocytes from patients with active multiple sclerosis exhibit increased surface expression of both HERV-H Env and HERV-W Env, accompanied by increased seroreactivity.
Retrovirology
Brudek T,Christensen T,Aagaard L,Petersen T,Hansen HJ,Møller-Larsen A
Published figure using CD4 monoclonal antibody (Product # 12-0049-42) in Flow Cytometry
Mon Nov 16 00:00:00 EST 2009
