Product References
Cathepsin S inhibition in dendritic cells prevents Th17 cell differentiation in perivascular adipose tissues following vascular injury in diabetic rats.
Journal of biochemical and molecular toxicology
Peng H,Lv Y,Li C,Cheng Z,He S,Wang C,Liu J
Published figure using CD4 monoclonal antibody (Product # 17-0049-42) in Flow Cytometry
Fri Sep 01 00:00:00 EDT 2023
Rapamycin improves Graves' orbitopathy by suppressing CD4+ cytotoxic T lymphocytes.
JCI insight
Zhang M,Chong KK,Chen ZY,Guo H,Liu YF,Kang YY,Li YJ,Shi TT,Lai KK,He MQ,Ye K,Kahaly GJ,Shi BY,Wang Y
Published figure using CD4 monoclonal antibody (Product # 17-0049-42) in Flow Cytometry
Wed Feb 08 00:00:00 EST 2023
Single-cell RNA sequencing reveals the molecular features of peripheral blood immune cells in children, adults and centenarians.
Frontiers in immunology
Zhong J,Ding R,Jiang H,Li L,Wan J,Feng X,Chen M,Peng L,Li X,Lin J,Yang H,Wang M,Li Q,Chen Q
Published figure using CD4 monoclonal antibody (Product # 17-0049-42) in Flow Cytometry
Mon Jan 30 00:00:00 EST 2023
Single-cell profiling of healthy human kidney reveals features of sex-based transcriptional programs and tissue-specific immunity.
Nature communications
McEvoy CM,Murphy JM,Zhang L,Clotet-Freixas S,Mathews JA,An J,Karimzadeh M,Pouyabahar D,Su S,Zaslaver O,Röst H,Arambewela R,Liu LY,Zhang S,Lawson KA,Finelli A,Wang B,MacParland SA,Bader GD,Konvalinka A,Crome SQ
Published figure using CD4 monoclonal antibody (Product # 17-0049-42) in Flow Cytometry
Sat Dec 10 00:00:00 EST 2022
Decoding the pathogenesis of Diamond-Blackfan anemia using single-cell RNA-seq.
Cell discovery
Wang B,Wang C,Wan Y,Gao J,Ma Y,Zhang Y,Tong J,Zhang Y,Liu J,Chang L,Xu C,Shen B,Chen Y,Jiang E,Kurita R,Nakamura Y,Lim KC,Engel JD,Zhou J,Cheng T,Zhu X,Zhu P,Shi L
Published figure using CD4 monoclonal antibody (Product # 17-0049-42) in Flow Cytometry
Tue May 10 00:00:00 EDT 2022
A nonredundant role for T cell-derived interleukin 22 in antibacterial defense of colonic crypts.
Immunity
Zindl CL,Witte SJ,Laufer VA,Gao M,Yue Z,Janowski KM,Cai B,Frey BF,Silberger DJ,Harbour SN,Singer JR,Turner H,Lund FE,Vallance BA,Rosenberg AF,Schoeb TR,Chen JY,Hatton RD,Weaver CT
17-0049-42 was used in Flow Cytometry to demonstrate spatiotemporal differences in the production and action of IL-22 by ILCs and T cells during infection and reveal an indispensable role for IL-22-producing T cells in the protection of the intestinal crypts.
Tue Mar 08 00:00:00 EST 2022
Dysregulated Peripheral Invariant Natural Killer T Cells in Plaque Psoriasis Patients.
Frontiers in cell and developmental biology
Hu Y,Chen Y,Chen Z,Zhang X,Guo C,Yu Z,Xu P,Sun L,Zhou X,Gong Y,Yu Q,Shi Y
17-0049-42 was used in Flow cytometry/Cell sorting to explore the expression of iNKT cells in psoriasis patients and the effect of secukinumab on them.
Wed Feb 23 00:00:00 EST 2022
Effects of the Antidiabetic Drugs Evogliptin and Sitagliptin on the Immune Function of CD26/DPP4 in Th1 Cells.
Biomolecules & therapeutics
Yoon H,Sung JH,Song MJ
Published figure using CD4 monoclonal antibody (Product # 17-0049-42) in Flow Cytometry
Mon Mar 01 00:00:00 EST 2021
Murlentamab, a Low Fucosylated Anti-Müllerian Hormone Type II Receptor (AMHRII) Antibody, Exhibits Anti-Tumor Activity through Tumor-Associated Macrophage Reprogrammation and T Cell Activation.
Cancers
Prat M,Salon M,Allain T,Dubreuil O,Noël G,Preisser L,Jean B,Cassard L,Lemée F,Tabah-Fish I,Pipy B,Jeannin P,Prost JF,Barret JM,Coste A
Published figure using CD4 monoclonal antibody (Product # 17-0049-42) in Flow Cytometry
Tue Apr 13 00:00:00 EDT 2021
Blockade of IDO-Kynurenine-AhR Axis Ameliorated Colitis-Associated Colon Cancer via Inhibiting Immune Tolerance.
Cellular and molecular gastroenterology and hepatology
Zhang X,Liu X,Zhou W,Du Q,Yang M,Ding Y,Hu R
17-0049-42 was used in Flow Cytometry to demonstrate that inhibition of IDO diminished Kyn/AhR-mediated Treg differentiation and could be an effective strategy for the prevention and treatment of inflammation-related colon cancer.
Fri Mar 25 00:00:00 EDT 2022
Characterization and modulation of anti-αβTCR antibodies and their respective binding sites at the βTCR chain to enrich engineered T cells.
Molecular therapy. Methods & clinical development
Kierkels GJJ,van Diest E,Hernández-López P,Scheper W,de Bruin ACM,Frijlink E,Aarts-Riemens T,van Dooremalen SFJ,Beringer DX,Oostvogels R,Kramer L,Straetemans T,Uckert W,Sebestyén Z,Kuball J
Published figure using CD4 monoclonal antibody (Product # 17-0049-42) in Flow Cytometry
Fri Sep 10 00:00:00 EDT 2021
Bispecific T-Cell Engaging Antibodies Against MUC16 Demonstrate Efficacy Against Ovarian Cancer in Monotherapy and in Combination With PD-1 and VEGF Inhibition.
Frontiers in immunology
Yeku OO,Rao TD,Laster I,Kononenko A,Purdon TJ,Wang P,Cui Z,Liu H,Brentjens RJ,Spriggs D
Published figure using CD4 monoclonal antibody (Product # 17-0049-42) in Flow Cytometry
Thu Oct 21 00:00:00 EDT 2021
An Integrated Epigenomic and Transcriptomic Map of Mouse and Human αβ T Cell Development.
Immunity
Chopp LB,Gopalan V,Ciucci T,Ruchinskas A,Rae Z,Lagarde M,Gao Y,Li C,Bosticardo M,Pala F,Livak F,Kelly MC,Hannenhalli S,Bosselut R
17-0049-42 was used in Flow Cytometry to identify mouse and human αβ thymocyte developmental trajectories.
Tue Dec 15 00:00:00 EST 2020
An Integrated Epigenomic and Transcriptomic Map of Mouse and Human αβ T Cell Development.
Immunity
Chopp LB,Gopalan V,Ciucci T,Ruchinskas A,Rae Z,Lagarde M,Gao Y,Li C,Bosticardo M,Pala F,Livak F,Kelly MC,Hannenhalli S,Bosselut R
17-0049-42 was used in Flow Cytometry to identify mouse and human αβ thymocyte developmental trajectories.
Tue Dec 15 00:00:00 EST 2020
Identification of two HLA-A*0201 immunogenic epitopes of lactate dehydrogenase C (LDHC): potential novel targets for cancer immunotherapy.
Cancer immunology, immunotherapy : CII
Thomas R,Shaath H,Naik A,Toor SM,Elkord E,Decock J
Published figure using CD4 monoclonal antibody (Product # 17-0049-42) in Flow Cytometry
Sun Mar 01 00:00:00 EST 2020
HDAC Inhibitor, CG-745, Enhances the Anti-Cancer Effect of Anti-PD-1 Immune Checkpoint Inhibitor by Modulation of the Immune Microenvironment.
Journal of Cancer
Kim YD,Park SM,Ha HC,Lee AR,Won H,Cha H,Cho S,Cho JM
Published figure using CD4 monoclonal antibody (Product # 17-0049-42) in Flow Cytometry
Mon Sep 28 00:00:00 EDT 2020
Involvement of natural killer cells in the pathogenesis of endometriosis in patients with pelvic pain.
The Journal of international medical research
He J,Xu Y,Yi M,Gu C,Zhu Y,Hu G
Published figure using CD4 monoclonal antibody (Product # 17-0049-42) in Flow Cytometry
Wed Jul 01 00:00:00 EDT 2020
Standardized 11-color flow cytometry panel for the functional phenotyping of human T regulatory cells.
Journal of biological methods
Manuszak C,Brainard M,Thrash E,Hodi FS,Severgnini M
Published figure using CD4 monoclonal antibody (Product # 17-0049-42) in Flow Cytometry
Mon Sep 28 00:00:00 EDT 2020
Loss of ARPC1B impairs cytotoxic T lymphocyte maintenance and cytolytic activity.
The Journal of clinical investigation
Randzavola LO,Strege K,Juzans M,Asano Y,Stinchcombe JC,Gawden-Bone CM,Seaman MN,Kuijpers TW,Griffiths GM
17-0049-42 was used in Flow cytometry/Cell sorting to show that loss of actin-related protein complex 1B led to loss of CD8 cytotoxic T lymphocytes cytotoxicity, with the defect arising at 2 different levels.
Mon Dec 02 00:00:00 EST 2019
Role of IL-35 in sublingual allergen immunotherapy.
The Journal of allergy and clinical immunology
Shamji MH,Layhadi JA,Achkova D,Kouser L,Perera-Webb A,Couto-Francisco NC,Parkin RV,Matsuoka T,Scadding G,Ashton-Rickardt PG,Durham SR
17-0049 was used in Flow cytometry/Cell sorting to investigate mechanisms underlying the induction and maintenance of immunologic tolerance induced by IL-35 and iTR35 cells.
Fri Mar 01 00:00:00 EST 2019
Immunological Properties of Neural Crest Cells Derived from Human Induced Pluripotent Stem Cells.
Stem cells and development
Fujii S,Yoshida S,Inagaki E,Hatou S,Tsubota K,Takahashi M,Shimmura S,Sugita S
17-0049 was used in Flow cytometry/Cell sorting to assess the immunological properties of human induced pluripotent stem cells-neural crest cells.
Tue Jan 01 00:00:00 EST 2019
MicroRNA‑155 inhibits the proliferation of CD8+ T cells via upregulating regulatory T cells in vitiligo.
Molecular medicine reports
Lv M,Li Z,Liu J,Lin F,Zhang Q,Li Z,Wang Y,Wang K,Xu Y
Published figure using CD4 monoclonal antibody (Product # 17-0049-42) in Flow Cytometry
Tue Oct 01 00:00:00 EDT 2019
Causes and Consequences of miR-150-5p Dysregulation in Myasthenia Gravis.
Frontiers in immunology
Cron MA,Maillard S,Truffault F,Gualeni AV,Gloghini A,Fadel E,Guihaire J,Behin A,Berrih-Aknin S,Le Panse R
17-0049 was used in Flow cytometry/Cell sorting to show miR-150-5p dysregulation can increase death of CD4+ and CD8+ T cells and induce overexpression of pro-apoptotic genes normally targeted by miR-150.
Tue Aug 04 00:00:00 EDT 2020
RAB11FIP5 Expression and Altered Natural Killer Cell Function Are Associated with Induction of HIV Broadly Neutralizing Antibody Responses.
Cell
Bradley T,Peppa D,Pedroza-Pacheco I,Li D,Cain DW,Henao R,Venkat V,Hora B,Chen Y,Vandergrift NA,Overman RG,Edwards RW,Woods CW,Tomaras GD,Ferrari G,Ginsburg GS,Connors M,Cohen MS,Moody MA,Borrow P,Haynes BF
Published figure using CD4 monoclonal antibody (Product # 17-0049-42) in Flow Cytometry
Thu Oct 04 00:00:00 EDT 2018
Lower High-Density Lipoproteins Levels During Human Immunodeficiency Virus Type 1 Infection Are Associated With Increased Inflammatory Markers and Disease Progression.
Frontiers in immunology
Marín-Palma D,Castro GA,Cardona-Arias JA,Urcuqui-Inchima S,Hernandez JC
17-0049 was used in Flow cytometry/Cell sorting to indicate that HDL might modulate the expression of several key components of the inflammasomes during HIV-1 infection, suggesting a novel role of HDL in modifying the inflammatory state and consequently, the progression of HIV-1 infection.
Mon Mar 21 00:00:00 EDT 2022
Abnormal expression of circulating and tumor-infiltrating carcinoembryonic antigen-related cell adhesion molecule 1 in patients with glioma.
Oncology letters
Li J,Liu X,Duan Y,Wang H,Su W,Wang Y,Zhuang G,Fan Y
17-0049-42 was used in Flow cytometry/Cell sorting to analyse associations between CEACAM1 expression and multiple clinicopathological characteristics in patients with gliomas.
Thu Mar 01 00:00:00 EST 2018
The Effects of High Mobility Group Box-1 Protein on Peripheral Treg/Th17 Balance in Patients with Atherosclerosis.
Acta Cardiologica Sinica
Ding JW,Zhou T,Zheng XX,Wang XA,Tong XH,Luo CY,Zhang ZQ,Yu B
Published figure using CD4 monoclonal antibody (Product # 17-0049-42) in Flow Cytometry
Sat Sep 01 00:00:00 EDT 2018
Activation-induced Markers Detect Vaccine-Specific CD4⁺ T Cell Responses Not Measured by Assays Conventionally Used in Clinical Trials.
Vaccines
Bowyer G,Rampling T,Powlson J,Morter R,Wright D,Hill AVS,Ewer KJ
17-0049 was used in Flow cytometry/Cell sorting to compare the use of markers for their sensitivity, specificity and associations with other measures of vaccine immunogenicity and demonstrate these as an additional method of reporting the T cell response to vaccination.
Tue Jul 31 00:00:00 EDT 2018
Non-neutralizing Antibodies Alter the Course of HIV-1 Infection In Vivo.
Cell
Horwitz JA,Bar-On Y,Lu CL,Fera D,Lockhart AAK,Lorenzi JCC,Nogueira L,Golijanin J,Scheid JF,Seaman MS,Gazumyan A,Zolla-Pazner S,Nussenzweig MC
Published figure using CD4 monoclonal antibody (Product # 17-0049-42) in Flow Cytometry
Thu Aug 10 00:00:00 EDT 2017
Spontaneous Chitin Accumulation in Airways and Age-Related Fibrotic Lung Disease.
Cell
Van Dyken SJ,Liang HE,Naikawadi RP,Woodruff PG,Wolters PJ,Erle DJ,Locksley RM
17-0049 was used in Flow cytometry/Cell sorting to show that altered chitin clearance could exacerbate fibrogenic pathways in the setting of lung diseases characterised by epithelial cell dysfunction.
Thu Apr 20 00:00:00 EDT 2017
Blocking the recruitment of naive CD4+ T cells reverses immunosuppression in breast cancer.
Cell research
Su S,Liao J,Liu J,Huang D,He C,Chen F,Yang L,Wu W,Chen J,Lin L,Zeng Y,Ouyang N,Cui X,Yao H,Su F,Huang JD,Lieberman J,Liu Q,Song E
Published figure using CD4 monoclonal antibody (Product # 17-0049-42) in Flow Cytometry
Sat Apr 01 00:00:00 EDT 2017
Recruited Monocytes and Type 2 Immunity Promote Lung Regeneration following Pneumonectomy.
Cell stem cell
Lechner AJ,Driver IH,Lee J,Conroy CM,Nagle A,Locksley RM,Rock JR
17-0049 was used in Flow cytometry/Cell sorting to provide evidence that group 2 innate lymphoid cells are a source of IL-13, which promotes lung regeneration.
Thu Jul 06 00:00:00 EDT 2017
Impact of Enhancer of Zeste Homolog 2 on T Helper Cell-Mediated Allergic Rhinitis.
Frontiers in immunology
Hou TY,Chen MR,Chou YC,Kan PC,Tsai YT,Cha TL
Published figure using CD4 monoclonal antibody (Product # 17-0049-42) in Flow Cytometry
Wed Nov 20 00:00:00 EST 2019
Protein kinase CK2 controls T-cell polarization through dendritic cell activation in response to contact sensitizers.
Journal of leukocyte biology
de Bourayne M,Gallais Y,El Ali Z,Rousseau P,Damiens MH,Cochet C,Filhol O,Chollet-Martin S,Pallardy M,Kerdine-Römer S
Published figure using CD4 monoclonal antibody (Product # 17-0049-42) in Flow Cytometry
Wed Mar 01 00:00:00 EST 2017
CXCL13-producing TFH cells link immune suppression and adaptive memory in human breast cancer.
JCI insight
Gu-Trantien C,Migliori E,Buisseret L,de Wind A,Brohée S,Garaud S,Noël G,Dang Chi VL,Lodewyckx JN,Naveaux C,Duvillier H,Goriely S,Larsimont D,Willard-Gallo K
Published figure using CD4 monoclonal antibody (Product # 17-0049-42) in Flow Cytometry
Fri Jun 02 00:00:00 EDT 2017
Remarkably low affinity of CD4/peptide-major histocompatibility complex class II protein interactions.
Proceedings of the National Academy of Sciences of the United States of America
Jönsson P,Southcombe JH,Santos AM,Huo J,Fernandes RA,McColl J,Lever M,Evans EJ,Hudson A,Chang VT,Hanke T,Godkin A,Dunne PD,Horrocks MH,Palayret M,Screaton GR,Petersen J,Rossjohn J,Fugger L,Dushek O,Xu XN,Davis SJ,Klenerman D
Published figure using CD4 monoclonal antibody (Product # 17-0049-42) in Flow Cytometry
Tue May 17 00:00:00 EDT 2016
Polymorphism in TGFB1 is associated with worse non-relapse mortality and overall survival after stem cell transplantation with unrelated donors.
Haematologica
Arrieta-Bolaños E,Mayor NP,Marsh SG,Madrigal JA,Apperley JF,Kirkland K,Mackinnon S,Marks DI,McQuaker G,Perry J,Potter MN,Russell NH,Thomson K,Shaw BE
17-0049 was used in Flow cytometry/Cell sorting to analyse the role of genetic variation in the regulatory region and exon 1 of TGFB1 on the outcome of unrelated donor hematopoietic stem cell transplantation.
Tue Mar 01 00:00:00 EST 2016
Chemical proteomic map of dimethyl fumarate-sensitive cysteines in primary human T cells.
Science signaling
Blewett MM,Xie J,Zaro BW,Backus KM,Altman A,Teijaro JR,Cravatt BF
17-0049 was used in Flow cytometry/Cell sorting to explore the mode of action of Dimethyl fumarate as a therapy for autoimmune diseases.
Tue Sep 13 00:00:00 EDT 2016
Interaction among activated lymphocytes and mesenchymal cells through podoplanin is critical for a high IL-17 secretion.
Arthritis research & therapy
Noack M,Ndongo-Thiam N,Miossec P
Published figure using CD4 monoclonal antibody (Product # 17-0049-42) in Flow Cytometry
Thu Jun 23 00:00:00 EDT 2016
Umbilical Cord-Derived Mesenchymal Stem Cells Suppress Autophagy of T Cells in Patients with Systemic Lupus Erythematosus via Transfer of Mitochondria.
Stem cells international
Chen J,Wang Q,Feng X,Zhang Z,Geng L,Xu T,Wang D,Sun L
17-0049 was used in Flow cytometry/Cell sorting to show that T cells from SLE patients had higher autophagic activity than that from healthy controls.
Thu Oct 01 00:00:00 EDT 2020
CD28 family of receptors on T cells in chronic HBV infection: Expression characteristics, clinical significance and correlations with PD-1 blockade.
Molecular medicine reports
Tang ZS,Hao YH,Zhang EJ,Xu CL,Zhou Y,Zheng X,Yang DL
Published figure using CD4 monoclonal antibody (Product # 17-0049-42) in Flow Cytometry
Mon Aug 01 00:00:00 EDT 2016
Equilibrium of Treg/Th17 cells of peripheral blood in syphilitic patients with sero-resistance.
Experimental and therapeutic medicine
Zhao J,Ma J,Zhang X,Li Q,Yang X
Published figure using CD4 monoclonal antibody (Product # 17-0049-42) in Flow Cytometry
Wed Jun 01 00:00:00 EDT 2016
Tuning of AKT-pathway by Nef and its blockade by protease inhibitors results in limited recovery in latently HIV infected T-cell line.
Scientific reports
Kumar A,Abbas W,Colin L,Khan KA,Bouchat S,Varin A,Larbi A,Gatot JS,Kabeya K,Vanhulle C,Delacourt N,Pasquereau S,Coquard L,Borch A,König R,Clumeck N,De Wit S,Rohr O,Rouzioux C,Fulop T,Van Lint C,Herbein G
Published figure using CD4 monoclonal antibody (Product # 17-0049-42) in Flow Cytometry
Thu Apr 14 00:00:00 EDT 2016
Lack of T Cell Response to iPSC-Derived Retinal Pigment Epithelial Cells from HLA Homozygous Donors.
Stem cell reports
Sugita S,Iwasaki Y,Makabe K,Kimura T,Futagami T,Suegami S,Takahashi M
Published figure using CD4 monoclonal antibody (Product # 17-0049-42) in Flow Cytometry
Tue Oct 11 00:00:00 EDT 2016
T-cell activation is an immune correlate of risk in BCG vaccinated infants.
Nature communications
Fletcher HA,Snowden MA,Landry B,Rida W,Satti I,Harris SA,Matsumiya M,Tanner R,O'Shea MK,Dheenadhayalan V,Bogardus L,Stockdale L,Marsay L,Chomka A,Harrington-Kandt R,Manjaly-Thomas ZR,Naranbhai V,Stylianou E,Darboe F,Penn-Nicholson A,Nemes E,Hatherill M,Hussey G,Mahomed H,Tameris M,McClain JB,Evans TG,Hanekom WA,Scriba TJ,McShane H
17-0049 was used in Flow cytometry/Cell sorting to identify immune characteristics that correlate with an increased risk of tuberculosis contraction using trial and study data.
Tue Apr 12 00:00:00 EDT 2016
Quantitative Proteomics of Gut-Derived Th1 and Th1/Th17 Clones Reveal the Presence of CD28+ NKG2D- Th1 Cytotoxic CD4+ T cells.
Molecular & cellular proteomics : MCP
Riaz T,Sollid LM,Olsen I,de Souza GA
17-0049 was used in Flow cytometry/Cell sorting to identify the proteomes of human Th1 and Th1/Th17 clones from intestinal biopsies of Crohn's patients and identify deferentially expressed proteins between the two phenotypes.
Tue Mar 01 00:00:00 EST 2016
Efficient gene disruption in cultured primary human endothelial cells by CRISPR/Cas9.
Circulation research
Abrahimi P,Chang WG,Kluger MS,Qyang Y,Tellides G,Saltzman WM,Pober JS
17-0049 was used in Flow cytometry/Cell sorting to demonstrate that the CRISPR/Cas9 modification of epithelial cells is a powerful platform for vascular research and for regenerative medicine.
Fri Jul 03 00:00:00 EDT 2015
Liposomal Glutathione Supplementation Restores TH1 Cytokine Response to Mycobacterium tuberculosis Infection in HIV-Infected Individuals.
Journal of interferon & cytokine research : the official journal of the International Society for Interferon and Cytokine Research
Ly J,Lagman M,Saing T,Singh MK,Tudela EV,Morris D,Anderson J,Daliva J,Ochoa C,Patel N,Pearce D,Venketaraman V
Published figure using CD4 monoclonal antibody (Product # 17-0049-42) in Flow Cytometry
Sun Nov 01 00:00:00 EDT 2015
Distinct patterns of intratumoral immune cell infiltrates in patients with HPV-associated compared to non-virally induced head and neck squamous cell carcinoma.
Oncoimmunology
Partlová S,Bouček J,Kloudová K,Lukešová E,Zábrodský M,Grega M,Fučíková J,Truxová I,Tachezy R,Špíšek R,Fialová A
Published figure using CD4 monoclonal antibody (Product # 17-0049-42) in Flow Cytometry
Thu Jan 01 00:00:00 EST 2015
dNP2 is a blood-brain barrier-permeable peptide enabling ctCTLA-4 protein delivery to ameliorate experimental autoimmune encephalomyelitis.
Nature communications
Lim S,Kim WJ,Kim YH,Lee S,Koo JH,Lee JA,Yoon H,Kim DH,Park HJ,Kim HM,Lee HG,Yun Kim J,Lee JU,Hun Shin J,Kyun Kim L,Doh J,Kim H,Lee SK,Bothwell ALM,Suh M,Choi JM
Published figure using CD4 monoclonal antibody (Product # 17-0049-42) in Flow Cytometry
Tue Sep 15 00:00:00 EDT 2015
Investigating the causes for decreased levels of glutathione in individuals with type II diabetes.
PloS one
Lagman M,Ly J,Saing T,Kaur Singh M,Vera Tudela E,Morris D,Chi PT,Ochoa C,Sathananthan A,Venketaraman V
Published figure using CD4 monoclonal antibody (Product # 17-0049-42) in Flow Cytometry
Wed Dec 30 00:00:00 EST 2015
A CD8 T cell/indoleamine 2,3-dioxygenase axis is required for mesenchymal stem cell suppression of human systemic lupus erythematosus.
Arthritis & rheumatology (Hoboken, N.J.)
Wang D,Feng X,Lu L,Konkel JE,Zhang H,Chen Z,Li X,Gao X,Lu L,Shi S,Chen W,Sun L
17-0049 was used in Flow cytometry/Cell sorting to highlight a previously unrecognised CD8+ T cell/IFNγ/IDO axis that mediates the therapeutic effects of allogeneic MSCs in lupus patients.
Fri Aug 01 00:00:00 EDT 2014
Immune response to JC virus T antigen in patients with and without colorectal neoplasia.
Gut microbes
Butcher LD,Garcia M,Arnold M,Ueno H,Goel A,Boland CR
17-0049 was used in Flow cytometry/Cell sorting to compare the immune response to JC virus T antigen in those with and without colorectal neoplasia.
Tue Jul 01 00:00:00 EDT 2014
Delta-like 1-mediated Notch signaling enhances the in vitro conversion of human memory CD4 T cells into FOXP3-expressing regulatory T cells.
Journal of immunology (Baltimore, Md. : 1950)
Mota C,Nunes-Silva V,Pires AR,Matoso P,Victorino RM,Sousa AE,Caramalho I
17-0049 was used in Flow cytometry/Cell sorting to investigate novel strategies to generate in vitro-induced Tregs.
Mon Dec 15 00:00:00 EST 2014
OMIP-022: Comprehensive assessment of antigen-specific human T-cell functionality and memory.
Cytometry. Part A : the journal of the International Society for Analytical Cytology
Graves AJ,Padilla MG,Hokey DA
Published figure using CD4 monoclonal antibody (Product # 17-0049-42) in Flow Cytometry
Tue Jul 01 00:00:00 EDT 2014
Sphingomyelin synthase 2, but not sphingomyelin synthase 1, is involved in HIV-1 envelope-mediated membrane fusion.
The Journal of biological chemistry
Hayashi Y,Nemoto-Sasaki Y,Tanikawa T,Oka S,Tsuchiya K,Zama K,Mitsutake S,Sugiura T,Yamashita A
17-0049 was used in Flow cytometry/Cell sorting to study a novel function of SMS2 which is the regulation of HIV-1 Env-mediated membrane fusion via actin rearrangement.
Fri Oct 31 00:00:00 EDT 2014
Assessment of CD4+ T cell responses to glutamic acid decarboxylase 65 using DQ8 tetramers reveals a pathogenic role of GAD65 121-140 and GAD65 250-266 in T1D development.
PloS one
Chow IT,Yang J,Gates TJ,James EA,Mai DT,Greenbaum C,Kwok WW
17-0049 was used in Flow cytometry/Cell sorting to suggest a pro-inflammatory role for T cells specific for DQ8-restricted epitopes and their possible contribution to type 1 diabetes progression.
Mon Jan 04 00:00:00 EST 2016
A truncation variant of the cation channel P2RX5 is upregulated during T cell activation.
PloS one
Abramowski P,Ogrodowczyk C,Martin R,Pongs O
17-0049 was used in Flow cytometry/Cell sorting to show that P2RX5 gene expression of human T lymphocytes is upregulated during activation.
Mon May 18 00:00:00 EDT 2015
The orally available, synthetic ether lipid edelfosine inhibits T cell proliferation and induces a type I interferon response.
PloS one
Abramowski P,Otto B,Martin R
17-0049 was used in Flow cytometry/Cell sorting to study how the inhibition of homeostatic proliferation, MHC class II expression and presentation, and the induction of type I interferon-associated genes could be used to develop edelfosine for clinical use in MS.
Thu Jan 22 00:00:00 EST 2015
Type 2 innate lymphoid cells control eosinophil homeostasis.
Nature
Nussbaum JC,Van Dyken SJ,von Moltke J,Cheng LE,Mohapatra A,Molofsky AB,Thornton EE,Krummel MF,Chawla A,Liang HE,Locksley RM
17-0049 was used in Flow cytometry/Cell sorting to investigate the processes underlying regulation of cytokine and chemokines for eosinophil development and survival, showing that type 2 innate lymphoid cells control eosinophil homeostasis.
Thu Oct 10 00:00:00 EDT 2013
HLA-DR15-derived self-peptides are involved in increased autologous T cell proliferation in multiple sclerosis.
Brain : a journal of neurology
Mohme M,Hotz C,Stevanovic S,Binder T,Lee JH,Okoniewski M,Eiermann T,Sospedra M,Rammensee HG,Martin R
17-0049 was used in Flow cytometry/Cell sorting to investigate perturbed T cell repertoire dynamics and the functional involvement of the major genetic risk factor, the HLA-DR15 haplotype, in multiple sclerosis.
Sat Jun 01 00:00:00 EDT 2013
Human regulatory T cells kill tumor cells through granzyme-dependent cytotoxicity upon retargeting with a bispecific antibody.
Cancer immunology research
Choi BD,Gedeon PC,Herndon JE,Archer GE,Reap EA,Sanchez-Perez L,Mitchell DA,Bigner DD,Sampson JH
Published figure using CD4 monoclonal antibody (Product # 17-0049-42) in Flow Cytometry
Sun Sep 01 00:00:00 EDT 2013
T cell epitope mapping of JC polyoma virus-encoded proteome reveals reduced T cell responses in HLA-DRB1*04:01+ donors.
Journal of virology
Jelcic I,Aly L,Binder TM,Jelcic I,Bofill-Mas S,Planas R,Demina V,Eiermann TH,Weber T,Girones R,Sospedra M,Martin R
17-0049 was used in Flow cytometry/Cell sorting to study the T cell response to JC polyomavirus in a group of predominantly HLA-DR-heterozygotic healthy donors.
Fri Mar 01 00:00:00 EST 2013
Evaluation of clinical and immunological responses: a 2-year follow-up study in children with allergic rhinitis due to house dust mite.
Mediators of inflammation
Moed H,Gerth van Wijk R,Hendriks RW,van der Wouden JC
17-0049 was used in Flow cytometry/Cell sorting to study allergic rhinitis clinical symptoms and associated in vivo/vitro skin and regulatory T cell responses respectively.
Tue Dec 03 00:00:00 EST 2013
Increased frequencies of Th22 cells as well as Th17 cells in the peripheral blood of patients with ankylosing spondylitis and rheumatoid arthritis.
PloS one
Zhang L,Li YG,Li YH,Qi L,Liu XG,Yuan CZ,Hu NW,Ma DX,Li ZF,Yang Q,Li W,Li JM
Published figure using CD4 monoclonal antibody (Product # 17-0049-42) in Flow Cytometry
Fri Jul 27 00:00:00 EDT 2012
Upregulation of programmed death-1 on T cells and programmed death ligand-1 on monocytes in septic shock patients.
Critical care (London, England)
Zhang Y,Li J,Lou J,Zhou Y,Bo L,Zhu J,Zhu K,Wan X,Cai Z,Deng X
Published figure using CD4 monoclonal antibody (Product # 17-0049-42) in Flow Cytometry
Wed Dec 07 00:00:00 EST 2011
Central role of JC virus-specific CD4+ lymphocytes in progressive multi-focal leucoencephalopathy-immune reconstitution inflammatory syndrome.
Brain : a journal of neurology
Aly L,Yousef S,Schippling S,Jelcic I,Breiden P,Matschke J,Schulz R,Bofill-Mas S,Jones L,Demina V,Linnebank M,Ogg G,Girones R,Weber T,Sospedra M,Martin R
17-0049 was used in Flow cytometry/Cell sorting to provide novel insight into the pathogenesis of progressive multi-focal leucoencephalopathy-immune reconstitution inflammatory syndrome.
Thu Sep 01 00:00:00 EDT 2011
Modulation of CD4+ T lymphocyte lineage outcomes with targeted, nanoparticle-mediated cytokine delivery.
Molecular pharmaceutics
Park J,Gao W,Whiston R,Strom TB,Metcalfe S,Fahmy TM
Published figure using CD4 monoclonal antibody (Product # 17-0049-42) in Flow Cytometry
Mon Feb 07 00:00:00 EST 2011
Differential expression of CD300a/c on human TH1 and TH17 cells.
BMC immunology
Simhadri VR,Mariano JL,Zhou Q,DeBell KE,Borrego F
17-0049 was used in Flow cytometry/Cell sorting to conclude that the CD300a/c receptors are differentially expressed on human TH1 and TH17 cells, and that their ligation is capable of modulating TCR mediated signals.
Wed Nov 02 00:00:00 EDT 2011
Memory T-cells and characterization of peripheral T-cell clones in acute Kawasaki disease.
Autoimmunity
Franco A,Shimizu C,Tremoulet AH,Burns JC
17-0049 was used in Flow cytometry/Cell sorting to provide insight into the nature and kinetics of the adaptive immune response in Kawasaki disease.
Tue Jun 01 00:00:00 EDT 2010
Human Th1 cells that express CD300a are polyfunctional and after stimulation up-regulate the T-box transcription factor eomesodermin.
PloS one
Narayanan S,Silva R,Peruzzi G,Alvarez Y,Simhadri VR,Debell K,Coligan JE,Borrego F
17-0049 was used in Flow cytometry/Cell sorting to investigate a subset within the CD4 T cell population defined by expression of the immunomodulatory receptor CD300a.
Thu May 13 00:00:00 EDT 2010
Frequency of gC1qR+CD4+ T cells increases during acute hepatitis C virus infection and remains elevated in patients with chronic infection.
Clinical immunology (Orlando, Fla.)
Cummings KL,Rosen HR,Hahn YS
17-0049 was used in Flow cytometry/Cell sorting to suggest that HCV infection expands gC1qR+CD4+ T cells, which ultimately facilitates the establishment of HCV persistency.
Tue Sep 01 00:00:00 EDT 2009
Sepsis-induced human lymphocyte apoptosis and cytokine production in "humanized" mice.
Journal of leukocyte biology
Unsinger J,McDonough JS,Shultz LD,Ferguson TA,Hotchkiss RS
Published figure using CD4 monoclonal antibody (Product # 17-0049-42) in Flow Cytometry
Sat Aug 01 00:00:00 EDT 2009
B cells and monocytes from patients with active multiple sclerosis exhibit increased surface expression of both HERV-H Env and HERV-W Env, accompanied by increased seroreactivity.
Retrovirology
Brudek T,Christensen T,Aagaard L,Petersen T,Hansen HJ,Møller-Larsen A
Published figure using CD4 monoclonal antibody (Product # 17-0049-42) in Flow Cytometry
Mon Nov 16 00:00:00 EST 2009
