Product References
Perinatal murine cytomegalovirus infection reshapes the transcriptional profile and functionality of NK cells.
Nature communications
Rožmanić C,Lisnić B,Pribanić Matešić M,Mihalić A,Hiršl L,Park E,Lesac Brizić A,Indenbirken D,Viduka I,Šantić M,Adler B,Yokoyama WM,Krmpotić A,Juranić Lisnić V,Jonjić S,Brizić I
Published figure using CD27 monoclonal antibody (Product # 12-0271-82) in Flow Cytometry
Thu Oct 12 00:00:00 EDT 2023
The transcription factor Bach2 negatively regulates murine natural killer cell maturation and function.
eLife
Li S,Bern MD,Miao B,Fan C,Xing X,Inoue T,Piersma SJ,Wang T,Colonna M,Kurosaki T,Yokoyama WM
Published figure using CD27 monoclonal antibody (Product # 12-0271-82) in Flow Cytometry
Mon Oct 03 00:00:00 EDT 2022
The transcriptional repressor ID2 supports natural killer cell maturation by controlling TCF1 amplitude.
The Journal of experimental medicine
Li ZY,Morman RE,Hegermiller E,Sun M,Bartom ET,Maienschein-Cline M,Sigvardsson M,Kee BL
Published figure using CD27 monoclonal antibody (Product # 12-0271-82) in Flow Cytometry
Mon Jun 07 00:00:00 EDT 2021
Chronic T cell proliferation in brains after stroke could interfere with the efficacy of immunotherapies.
The Journal of experimental medicine
Heindl S,Ricci A,Carofiglio O,Zhou Q,Arzberger T,Lenart N,Franzmeier N,Hortobagyi T,Nelson PT,Stowe AM,Denes A,Edbauer D,Liesz A
Published figure using CD27 monoclonal antibody (Product # 12-0271-82) in Flow Cytometry
Mon Aug 02 00:00:00 EDT 2021
PI3Kδ coordinates transcriptional, chromatin, and metabolic changes to promote effector CD8+ T cells at the expense of central memory.
Cell reports
Cannons JL,Villarino AV,Kapnick SM,Preite S,Shih HY,Gomez-Rodriguez J,Kaul Z,Shibata H,Reilley JM,Huang B,Handon R,McBain IT,Gossa S,Wu T,Su HC,McGavern DB,O'Shea JJ,McGuire PJ,Uzel G,Schwartzberg PL
Published figure using CD27 monoclonal antibody (Product # 12-0271-82) in Flow Cytometry
Tue Oct 12 00:00:00 EDT 2021
Effect of Subcutaneous Anti-CD20 Antibody-Mediated B Cell Depletion on Susceptibility to Pneumocystis Infection in Mice.
mSphere
Dai G,Noell K,Weckbecker G,Kolls JK
Published figure using CD27 monoclonal antibody (Product # 12-0271-82) in Flow Cytometry
Wed May 05 00:00:00 EDT 2021
Immune cell phenotypes associated with disease severity and long-term neutralizing antibody titers after natural dengue virus infection.
Cell reports. Medicine
Rouers A,Chng MHY,Lee B,Rajapakse MP,Kaur K,Toh YX,Sathiakumar D,Loy T,Thein TL,Lim VWX,Singhal A,Yeo TW,Leo YS,Vora KA,Casimiro D,Lim B,Tucker-Kellogg L,Rivino L,Newell EW,Fink K
Published figure using CD27 monoclonal antibody (Product # 12-0271-82) in Flow Cytometry
Tue May 18 00:00:00 EDT 2021
Development of a VRC01-class germline targeting immunogen derived from anti-idiotypic antibodies.
Cell reports
Seydoux E,Wan YH,Feng J,Wall A,Aljedani S,Homad LJ,MacCamy AJ,Weidle C,Gray MD,Brumage L,Taylor JJ,Pancera M,Stamatatos L,McGuire AT
Published figure using CD27 monoclonal antibody (Product # 12-0271-82) in Flow Cytometry
Tue May 04 00:00:00 EDT 2021
Ontogenic timing, T cell receptor signal strength, and Notch signaling direct γδ T cell functional differentiation in vivo.
Cell reports
Chen ELY,Lee CR,Thompson PK,Wiest DL,Anderson MK,Zúñiga-Pflücker JC
Published figure using CD27 monoclonal antibody (Product # 12-0271-82) in Flow Cytometry
Tue Jun 08 00:00:00 EDT 2021
Heterogenous Populations of Tissue-Resident CD8+ T Cells Are Generated in Response to Infection and Malignancy.
Immunity
Milner JJ,Toma C,He Z,Kurd NS,Nguyen QP,McDonald B,Quezada L,Widjaja CE,Witherden DA,Crowl JT,Shaw LA,Yeo GW,Chang JT,Omilusik KD,Goldrath AW
12-0271 was used in Flow cytometry/Cell sorting to identify discrete lineages of intestinal antigen-specific CD8+ T cells, including a Blimp1hiId3lo tissue-resident effector cell population most prominent in the early phase of acute viral and bacterial infections and a molecularly distinct Blimp1loId3hi tissue-resident memory population that subsequently accumulated at later infection time points.
Tue May 19 00:00:00 EDT 2020
SRC-3 Functions as a Coactivator of T-bet by Regulating the Maturation and Antitumor Activity of Natural Killer Cells.
Cancer immunology research
Hu M,Lu Y,Qi Y,Zhang Z,Wang S,Xu Y,Chen F,Tang Y,Chen S,Chen M,Du C,Shen M,Wang F,Su Y,Deng Y,Wang J
12-0271-82 was used in Flow Cytometry to study the role of SRC-3 as a coactivator of T-bet in natural killer-cell biology and indicate that targeting SRC-3 may be a promising strategy to increase the tumor surveillance function of natural killer cells.
Tue Sep 01 00:00:00 EDT 2020
Th2 Biased Immunity With Altered B Cell Profiles in Circulation of Patients With Sporotrichosis Caused by Sporothrix globosa.
Frontiers in immunology
Zu J,Yao L,Song Y,Cui Y,Guan M,Chen R,Zhen Y,Li S
12-0271 was used in Flow cytometry/Cell sorting to shed light on the potential involvement of peripheral T and B cell immunity against this mycotic infection.
Mon May 31 00:00:00 EDT 2021
Th2 Biased Immunity With Altered B Cell Profiles in Circulation of Patients With Sporotrichosis Caused by Sporothrix globosa.
Frontiers in immunology
Zu J,Yao L,Song Y,Cui Y,Guan M,Chen R,Zhen Y,Li S
12-0271 was used in Flow cytometry/Cell sorting to shed light on the potential involvement of peripheral T and B cell immunity against this mycotic infection.
Mon May 31 00:00:00 EDT 2021
Diverse CD8 T Cell Responses to Viral Infection Revealed by the Collaborative Cross.
Cell reports
Martin MD,Sompallae R,Winborn CS,Harty JT,Badovinac VP
12-0271 was used in Flow cytometry/Cell sorting to advance the utility of the Collaborative Cross (CC) as a tool to analyze the immune response to viral infection.
Tue Apr 14 00:00:00 EDT 2020
The cis-Regulatory Atlas of the Mouse Immune System.
Cell
Yoshida H,Lareau CA,Ramirez RN,Rose SA,Maier B,Wroblewska A,Desland F,Chudnovskiy A,Mortha A,Dominguez C,Tellier J,Kim E,Dwyer D,Shinton S,Nabekura T,Qi Y,Yu B,Robinette M,Kim KW,Wagers A,Rhoads A,Nutt SL,Brown BD,Mostafavi S,Buenrostro JD,Benoist C
12-0271-82 was used in Flow Cytometry to generate matched epigenome and transcriptome measurements in 86 primary cell types that span the mouse immune system and its differentiation cascade.
Thu Feb 07 00:00:00 EST 2019
Synergized regulation of NK cell education by NKG2A and specific Ly49 family members.
Nature communications
Zhang X,Feng J,Chen S,Yang H,Dong Z
12-0271 was used in Flow cytometry/Cell sorting to provide genetic evidence supporting that NKG2A and the inhibitory members of Ly49 family receptors synergize to regulate NK cell education.
Fri Nov 01 00:00:00 EDT 2019
Qa-1-Restricted CD8+ T Cells Can Compensate for the Absence of Conventional T Cells during Viral Infection.
Cell reports
Anderson CK,Reilly EC,Lee AY,Brossay L
12-0271 was used in Flow cytometry/Cell sorting to study compensatory mechanisms in immune responses to viruses when classical T cell immunity has been evaded.
Tue Apr 09 00:00:00 EDT 2019
Persistence of Integrase-Deficient Lentiviral Vectors Correlates with the Induction of STING-Independent CD8+ T Cell Responses.
Cell reports
Cousin C,Oberkampf M,Felix T,Rosenbaum P,Weil R,Fabrega S,Morante V,Negri D,Cara A,Dadaglio G,Leclerc C
12-0271 was used in Flow cytometry/Cell sorting to demonstrate that integrase-deficient lentiviral vectors can trigger persistent adaptive response by the mediation of a weak and transient innate response alongside the persistence of the vector in tissues.
Tue Jan 29 00:00:00 EST 2019
BALDR: a computational pipeline for paired heavy and light chain immunoglobulin reconstruction in single-cell RNA-seq data.
Genome medicine
Upadhyay AA,Kauffman RC,Wolabaugh AN,Cho A,Patel NB,Reiss SM,Havenar-Daughton C,Dawoud RA,Tharp GK,Sanz I,Pulendran B,Crotty S,Lee FE,Wrammert J,Bosinger SE
Published figure using CD27 monoclonal antibody (Product # 12-0271-82) in Flow Cytometry
Tue Mar 20 00:00:00 EDT 2018
Crosstalks between mTORC1 and mTORC2 variagate cytokine signaling to control NK maturation and effector function.
Nature communications
Wang F,Meng M,Mo B,Yang Y,Ji Y,Huang P,Lai W,Pan X,You T,Luo H,Guan X,Deng Y,Yuan S,Chu J,Namaka M,Hughes T,Ye L,Yu J,Li X,Deng Y
Published figure using CD27 monoclonal antibody (Product # 12-0271-82) in Flow Cytometry
Mon Nov 19 00:00:00 EST 2018
Loss of HIF-1α in natural killer cells inhibits tumour growth by stimulating non-productive angiogenesis.
Nature communications
Krzywinska E,Kantari-Mimoun C,Kerdiles Y,Sobecki M,Isagawa T,Gotthardt D,Castells M,Haubold J,Millien C,Viel T,Tavitian B,Takeda N,Fandrey J,Vivier E,Sexl V,Stockmann C
12-0271 was used in Flow cytometry/Cell sorting to investigate the mechanisms by which loss of HIF1α in natural killer cells inhibits tumour growth.
Fri Nov 17 00:00:00 EST 2017
The breast tumor microenvironment alters the phenotype and function of natural killer cells.
Cellular & molecular immunology
Krneta T,Gillgrass A,Chew M,Ashkar AA
Published figure using CD27 monoclonal antibody (Product # 12-0271-82) in Flow Cytometry
Thu Sep 01 00:00:00 EDT 2016
NK cell development requires Tsc1-dependent negative regulation of IL-15-triggered mTORC1 activation.
Nature communications
Yang M,Chen S,Du J,He J,Wang Y,Li Z,Liu G,Peng W,Zeng X,Li D,Xu P,Guo W,Chang Z,Wang S,Tian Z,Dong Z
Wed Sep 07 00:00:00 EDT 2016
Production of IL-10 by CD4(+) regulatory T cells during the resolution of infection promotes the maturation of memory CD8(+) T cells.
Nature immunology
Laidlaw BJ,Cui W,Amezquita RA,Gray SM,Guan T,Lu Y,Kobayashi Y,Flavell RA,Kleinstein SH,Craft J,Kaech SM
Published figure using CD27 monoclonal antibody (Product # 12-0271-82) in Flow Cytometry
Sat Aug 01 00:00:00 EDT 2015
Plasmodium suppresses expansion of T cell responses to heterologous infections.
Journal of immunology (Baltimore, Md. : 1950)
White CE,Villarino NF,Sloan SS,Ganusov VV,Schmidt NW
12-0271 was used in Flow cytometry/Cell sorting to investigate the mechanisms by which Plasmodium suppresses the expansion of T cell responses to heterologous coinfections.
Thu Jan 15 00:00:00 EST 2015
Identification and characterization of latency-associated peptide-expressing γδ T cells.
Nature communications
Rezende RM,da Cunha AP,Kuhn C,Rubino S,M'Hamdi H,Gabriely G,Vandeventer T,Liu S,Cialic R,Pinheiro-Rosa N,Oliveira RP,Gaublomme JT,Obholzer N,Kozubek J,Pochet N,Faria AMC,Weiner HL
12-0271 was used in Flow cytometry/Cell sorting to describe a subset of regulatory γδ T cells that express the latency-associated peptide, a membrane-bound TGF-β1.
Tue Dec 08 00:00:00 EST 2015
Sm29, but not Sm22.6 retains its ability to induce a protective immune response in mice previously exposed to a Schistosoma mansoni infection.
PLoS neglected tropical diseases
Alves CC,Araujo N,dos Santos VC,Couto FB,Assis NR,Morais SB,Oliveira SC,Fonseca CT
12-0271 was used in Flow cytometry/Cell sorting to investigate the potential of Sm29 and Sm22.6 as promising antigens to compose a vaccine against schistosomiasis.
Sun Feb 01 00:00:00 EST 2015
Viral MHC class I-like molecule allows evasion of NK cell effector responses in vivo.
Journal of immunology (Baltimore, Md. : 1950)
Pyzik M,Dumaine A,Charbonneau B,Fodil-Cornu N,Jonjic S,Vidal SM
12-0271 was used in Flow cytometry/Cell sorting to show that recognition of the viral protein m157 by the inhibitory Ly49C receptor allows escape from natural killer cell control of viral replication.
Mon Dec 15 00:00:00 EST 2014
The Menin-Bach2 axis is critical for regulating CD4 T-cell senescence and cytokine homeostasis.
Nature communications
Kuwahara M,Suzuki J,Tofukuji S,Yamada T,Kanoh M,Matsumoto A,Maruyama S,Kometani K,Kurosaki T,Ohara O,Nakayama T,Yamashita M
12-0271 was used in Flow cytometry/Cell sorting to show that T cell-specific Menin deficiency results in the premature senescence of CD4 T cells, which is accompanied by the senescence-associated secretory phenotype after antigenic stimulation and dysregulated cytokine production.
Wed Apr 02 00:00:00 EDT 2014
IL-33 signaling regulates innate and adaptive immunity to Cryptococcus neoformans.
Journal of immunology (Baltimore, Md. : 1950)
Flaczyk A,Duerr CU,Shourian M,Lafferty EI,Fritz JH,Qureshi ST
12-0271 was used in Flow cytometry/Cell sorting to study how allergic patterns of lung inflammation are mediated as a host response to Cryptococcus neoformans infection.
Sun Sep 01 00:00:00 EDT 2013
Markers of nonselective and specific NK cell activation.
Journal of immunology (Baltimore, Md. : 1950)
Fogel LA,Sun MM,Geurs TL,Carayannopoulos LN,French AR
12-0271 was used in Flow cytometry/Cell sorting to demonstrate that a combination of Sca-1, CD27, and KLRG1 can distinguish NK cells based on their mechanism of activation.
Sat Jun 15 00:00:00 EDT 2013
Role of NK cell subsets in organ-specific murine melanoma metastasis.
PloS one
Ballas ZK,Buchta CM,Rosean TR,Heusel JW,Shey MR
12-0271 was used in Flow cytometry/Cell sorting to examine the organ-specific functions of natural killer cells.
Thu Jan 16 00:00:00 EST 2014
Tumor necrosis factor induces tumor promoting and anti-tumoral effects on pancreatic cancer via TNFR1.
PloS one
Chopra M,Lang I,Salzmann S,Pachel C,Kraus S,Bäuerlein CA,Brede C,Garrote AL,Mattenheimer K,Ritz M,Schwinn S,Graf C,Schäfer V,Frantz S,Einsele H,Wajant H,Beilhack A
12-0271 was used in Flow cytometry/Cell sorting to assess the mechanisms underlying the contribution of tumour necrosis factor to carcinogenesis.
Mon May 12 00:00:00 EDT 2014
Nucleoside salvage pathway kinases regulate hematopoiesis by linking nucleotide metabolism with replication stress.
The Journal of experimental medicine
Austin WR,Armijo AL,Campbell DO,Singh AS,Hsieh T,Nathanson D,Herschman HR,Phelps ME,Witte ON,Czernin J,Radu CG
12-0271 was used in Flow cytometry/Cell sorting to investigate a functional link between nucleotide deficiency, replication stress, and two enzymes of the nucleoside salvage pathway: deoxycytidine kinase and thymidine kinase.
Mon Nov 19 00:00:00 EST 2012
CD4 T cells play important roles in maintaining IL-17-producing γδ T-cell subsets in naive animals.
Immunology and cell biology
Do JS,Visperas A,O'Brien RL,Min B
12-0271 was used in Flow cytometry/Cell sorting to investigate the mechanism underlying the regulation of αβ and γδ T-cell homeostasis, showing that CD4 T cells play important roles in maintaining IL-17-producing subsets.
Sun Apr 01 00:00:00 EDT 2012
Cutting edge: attrition of Plasmodium-specific memory CD8 T cells results in decreased protection that is rescued by booster immunization.
Journal of immunology (Baltimore, Md. : 1950)
Schmidt NW,Harty JT
12-0271 was used in Flow cytometry/Cell sorting to investigate whether unrelated infections will compromise numbers of Plasmodium-specific memory CD8 T cells, showing that attrition of Plasmodium-specific cells is rescued by booster immunisation.
Fri Apr 01 00:00:00 EDT 2011
Plasmodium-host interactions directly influence the threshold of memory CD8 T cells required for protective immunity.
Journal of immunology (Baltimore, Md. : 1950)
Schmidt NW,Butler NS,Harty JT
12-0271 was used in Flow cytometry/Cell sorting to investigate how the threshold of memory CD8 T cells required for protective immunity is influenced by Plasmodium-host interactions.
Sun May 15 00:00:00 EDT 2011
Heterogeneity among viral antigen-specific CD4+ T cells and their de novo recruitment during persistent polyomavirus infection.
Journal of immunology (Baltimore, Md. : 1950)
Lin E,Kemball CC,Hadley A,Wilson JJ,Hofstetter AR,Pack CD,Lukacher AE
12-0271 was used in Flow cytometry/Cell sorting to investigate the heterogeneity in the viral antigen-specific CD4+ T cell responses to chronic polyomavirus infection.
Sun Aug 01 00:00:00 EDT 2010
IL-7 and IL-15 differentially regulate CD8+ T-cell subsets during contraction of the immune response.
Blood
Rubinstein MP,Lind NA,Purton JF,Filippou P,Best JA,McGhee PA,Surh CD,Goldrath AW
12-0271 was used in Flow cytometry/Cell sorting to study IL-7 and IL-15 regulation of CD8+ T-cell subsets during contraction of the immune response.
Sat Nov 01 00:00:00 EDT 2008
E47 controls the developmental integrity and cell cycle quiescence of multipotential hematopoietic progenitors.
Journal of immunology (Baltimore, Md. : 1950)
Yang Q,Kardava L,St Leger A,Martincic K,Varnum-Finney B,Bernstein ID,Milcarek C,Borghesi L
12-0271 was used in Flow cytometry/Cell sorting to show E47 controls the developmental integrity and cell cycle quiescence of hematopoietic progenitors.
Sat Nov 01 00:00:00 EDT 2008
Late signals from CD27 prevent Fas-dependent apoptosis of primary CD8+ T cells.
Journal of immunology (Baltimore, Md. : 1950)
Dolfi DV,Boesteanu AC,Petrovas C,Xia D,Butz EA,Katsikis PD
12-0271 was used in Flow cytometry/Cell sorting to demonstrate a novel mechanism of CD27 costimulation, and its role in late stage CD8+ T cell response to influenza virus.
Sat Mar 01 00:00:00 EST 2008
The latency-associated nuclear antigen of Kaposi sarcoma-associated herpesvirus induces B cell hyperplasia and lymphoma.
The Journal of clinical investigation
Fakhari FD,Jeong JH,Kanan Y,Dittmer DP
12-0271 was used in Flow cytometry/Cell sorting to assess the contribution of Kaposi sarcoma-associated herpesvirus latency-associated nuclear antigen to lymphomagenesis.
Wed Mar 01 00:00:00 EST 2006
Delayed, asynchronous, and reversible T-lineage specification induced by Notch/Delta signaling.
Genes & development
Taghon TN,David ES,Zúñiga-Pflücker JC,Rothenberg EV
12-0271 was used in Flow cytometry/Cell sorting to study how Notch/Delta signaling is not sufficient for T-lineage specification and commitment, but can be permissive for the maintenance and proliferation of uncommitted progenitors.
Fri Apr 15 00:00:00 EDT 2005
