Product References
Forsythiaside A Improves the Inhibitory Efficiency of Recombinant Protein Vaccines against Bovine Viral Diarrhea Virus Infection.
International journal of molecular sciences
Yang G,Wang J,Wang S,Zhu Y
Published figure using IL-2 monoclonal antibody (Product # 13-7021-81) in Flow Cytometry
Sat Aug 20 00:00:00 EDT 2022
In vivo genome-wide CRISPR screening identifies ZNF24 as a negative NF-κB modulator in lung cancer.
Cell & bioscience
Liu L,Lei Y,Chen W,Zhou Q,Zheng Z,Zeng G,Liu W,Feng P,Zhang Z,Yu L,Chen L
Published figure using IL-2 monoclonal antibody (Product # 13-7021-81) in Flow Cytometry
Thu Dec 01 00:00:00 EST 2022
Z. morio Hemolymph Relieves E. coli-Induced Mastitis by Inhibiting Inflammatory Response and Repairing the Blood-Milk Barrier.
International journal of molecular sciences
Zou Y,Wang X,Xu J,Wang S,Li S,Zhu Y,Wang J
Published figure using IL-2 monoclonal antibody (Product # 13-7021-81) in Flow Cytometry
Mon Oct 31 00:00:00 EDT 2022
Impaired Treg-DC interactions contribute to autoimmunity in leukocyte adhesion deficiency type 1.
JCI insight
Klaus T,Wilson AS,Vicari E,Hadaschik E,Klein M,Helbich SSC,Kamenjarin N,Hodapp K,Schunke J,Haist M,Butsch F,Probst HC,Enk AH,Mahnke K,Waisman A,Bednarczyk M,Bros M,Bopp T,Grabbe S
Published figure using IL-2 monoclonal antibody (Product # 13-7021-81) in Flow Cytometry
Thu Dec 22 00:00:00 EST 2022
A Methyltransferase-Defective Vesicular Stomatitis Virus-Based SARS-CoV-2 Vaccine Candidate Provides Complete Protection against SARS-CoV-2 Infection in Hamsters.
Journal of virology
Lu M,Zhang Y,Dravid P,Li A,Zeng C,Kc M,Trivedi S,Sharma H,Chaiwatpongsakorn S,Zani A,Kenney A,Cai C,Ye C,Liang X,Qiu J,Martinez-Sobrido L,Yount JS,Boyaka PN,Liu SL,Peeples ME,Kapoor A,Li J
Published figure using IL-2 monoclonal antibody (Product # 13-7021-81) in Flow Cytometry
Mon Sep 27 00:00:00 EDT 2021
Local Sustained GM-CSF Delivery by Genetically Engineered Encapsulated Cells Enhanced Both Cellular and Humoral SARS-CoV-2 Spike-Specific Immune Response in an Experimental Murine Spike DNA Vaccination Model.
Vaccines
Vernet R,Charrier E,Cosset E,Fièvre S,Tomasello U,Grogg J,Mach N
Published figure using IL-2 monoclonal antibody (Product # 13-7021-81) in Flow Cytometry
Mon May 10 00:00:00 EDT 2021
Blocking interaction between SHP2 and PD-1 denotes a novel opportunity for developing PD-1 inhibitors.
EMBO molecular medicine
Fan Z,Tian Y,Chen Z,Liu L,Zhou Q,He J,Coleman J,Dong C,Li N,Huang J,Xu C,Zhang Z,Gao S,Zhou P,Ding K,Chen L
Published figure using IL-2 monoclonal antibody (Product # 13-7021-81) in Flow Cytometry
Mon Jun 08 00:00:00 EDT 2020
Deletion Timing of Cic Alleles during Hematopoiesis Determines the Degree of Peripheral CD4+ T Cell Activation and Proliferation.
Immune network
Park GY,Lee GW,Kim S,Hong H,Park JS,Cho JH,Lee Y
Published figure using IL-2 monoclonal antibody (Product # 13-7021-81) in ELISA
Thu Oct 01 00:00:00 EDT 2020
Deletion Timing of Cic Alleles during Hematopoiesis Determines the Degree of Peripheral CD4+ T Cell Activation and Proliferation.
Immune network
Park GY,Lee GW,Kim S,Hong H,Park JS,Cho JH,Lee Y
Published figure using IL-2 monoclonal antibody (Product # 13-7021-81) in ELISA
Thu Oct 01 00:00:00 EDT 2020
Synthetic DNA Vaccines Adjuvanted with pIL-33 Drive Liver-Localized T Cells and Provide Protection from Plasmodium Challenge in a Mouse Model.
Vaccines
Reeder SM,Reuschel EL,Bah MA,Yun K,Tursi NJ,Kim KY,Chu J,Zaidi FI,Yilmaz I,Hart RJ,Perrin B,Xu Z,Humeau L,Weiner DB,Aly ASI
Published figure using IL-2 monoclonal antibody (Product # 13-7021-81) in Flow Cytometry
Fri Jan 10 00:00:00 EST 2020
Deletion of immune evasion genes provides an effective vaccine design for tumor-associated herpesviruses.
NPJ vaccines
Brar G,Farhat NA,Sukhina A,Lam AK,Kim YH,Hsu T,Tong L,Lin WW,Ware CF,Blackman MA,Sun R,Wu TT
Published figure using IL-2 monoclonal antibody (Product # 13-7021-81) in Flow Cytometry
Thu Nov 05 00:00:00 EST 2020
Rab6-dependent retrograde traffic of LAT controls immune synapse formation and T cell activation.
The Journal of experimental medicine
Carpier JM,Zucchetti AE,Bataille L,Dogniaux S,Shafaq-Zadah M,Bardin S,Lucchino M,Maurin M,Joannas LD,Magalhaes JG,Johannes L,Galli T,Goud B,Hivroz C
14-5931 was used in ELISA to show the role of MKP5 in restraining p38 MAPK-mediated neutrophil oxidant production, thereby preventing LPS-induced vascular injury in mice.
Mon Apr 02 00:00:00 EDT 2018
Opposing Roles of Dendritic Cell Subsets in Experimental GN.
Journal of the American Society of Nephrology : JASN
Brähler S,Zinselmeyer BH,Raju S,Nitschke M,Suleiman H,Saunders BT,Johnson MW,Böhner AMC,Viehmann SF,Theisen DJ,Kretzer NM,Briseño CG,Zaitsev K,Ornatsky O,Chang Q,Carrero JA,Kopp JB,Artyomov MN,Kurts C,Murphy KM,Miner JH,Shaw AS
13-7021 was used in an ELISA assay to study the function of dendritic cells in renal inflammation using DC specific reporters.
Mon Jan 01 00:00:00 EST 2018
Excessive expression of miR-27 impairs Treg-mediated immunological tolerance.
The Journal of clinical investigation
Cruz LO,Hashemifar SS,Wu CJ,Cho S,Nguyen DT,Lin LL,Khan AA,Lu LF
Published figure using IL-2 monoclonal antibody (Product # 13-7021-81) in Flow Cytometry
Wed Feb 01 00:00:00 EST 2017
Vaccination with High-Affinity Epitopes Impairs Antitumor Efficacy by Increasing PD-1 Expression on CD8+ T Cells.
Cancer immunology research
Zahm CD,Colluru VT,McNeel DG
Published figure using IL-2 monoclonal antibody (Product # 13-7021-81) in Flow Cytometry
Tue Aug 01 00:00:00 EDT 2017
A New Adjuvant MTOM Mediates Mycobacterium tuberculosis Subunit Vaccine to Enhance Th1-Type T Cell Immune Responses and IL-2+ T Cells.
Frontiers in immunology
Yu Q,Wang X,Fan X
Published figure using IL-2 monoclonal antibody (Product # 13-7021-81) in Flow Cytometry
Wed Nov 20 00:00:00 EST 2019
Toll like Receptor 2 engagement on CD4+ T cells promotes TH9 differentiation and function.
European journal of immunology
Karim AF,Reba SM,Li Q,Boom WH,Rojas RE
13-7021 was used in an ELISA assay to study the role of T-cell expressed TLR2 on CD4+ T-cell differentiation and function.
Fri Sep 01 00:00:00 EDT 2017
Capicua deficiency induces autoimmunity and promotes follicular helper T cell differentiation via derepression of ETV5.
Nature communications
Park S,Lee S,Lee CG,Park GY,Hong H,Lee JS,Kim YM,Lee SB,Hwang D,Choi YS,Fryer JD,Im SH,Lee SW,Lee Y
13-7021 was used in an ELISA assay to investigate the role of Capicua in autoimmunity.
Wed Jul 12 00:00:00 EDT 2017
Tristetraprolin inhibits macrophage IL-27-induced activation of antitumour cytotoxic T cell responses.
Nature communications
Wang Q,Ning H,Peng H,Wei L,Hou R,Hoft DF,Liu J
Published figure using IL-2 monoclonal antibody (Product # 13-7021-81) in Flow Cytometry
Wed Oct 11 00:00:00 EDT 2017
A Multistage Subunit Vaccine Effectively Protects Mice Against Primary Progressive Tuberculosis, Latency and Reactivation.
EBioMedicine
Ma J,Teng X,Wang X,Fan X,Wu Y,Tian M,Zhou Z,Li L
Published figure using IL-2 monoclonal antibody (Product # 13-7021-81) in Flow Cytometry
Tue Aug 01 00:00:00 EDT 2017
Immunogenicity and protective efficacy of DMT liposome-adjuvanted tuberculosis subunit CTT3H vaccine.
Human vaccines & immunotherapeutics
Teng X,Tian M,Li J,Tan S,Yuan X,Yu Q,Jing Y,Zhang Z,Yue T,Zhou L,Fan X
Published figure using IL-2 monoclonal antibody (Product # 13-7021-81) in Flow Cytometry
Fri Mar 11 00:00:00 EST 2016
TLR2 engagement on CD4(+) T cells enhances effector functions and protective responses to Mycobacterium tuberculosis.
European journal of immunology
Reba SM,Li Q,Onwuzulike S,Ding X,Karim AF,Hernandez Y,Fulton SA,Harding CV,Lancioni CL,Nagy N,Rodriguez ME,Wearsch PA,Rojas RE
Published figure using IL-2 monoclonal antibody (Product # 13-7021-81) in Flow Cytometry
Thu May 01 00:00:00 EDT 2014
Analysis of the vaccine potential of plasmid DNA encoding nine mycolactone polyketide synthase domains in Mycobacterium ulcerans infected mice.
PLoS neglected tropical diseases
Roupie V,Pidot SJ,Einarsdottir T,Van Den Poel C,Jurion F,Stinear TP,Huygen K
13-7021 was used in an ELISA assay to analyse the vaccine potential of nine polyketide synthase domains using a DNA prime/protein boost strategy.
Mon Sep 08 00:00:00 EDT 2014
T cells translate individual, quantal activation into collective, analog cytokine responses via time-integrated feedbacks.
eLife
Tkach KE,Barik D,Voisinne G,Malandro N,Hathorn MM,Cotari JW,Vogel R,Merghoub T,Wolchok J,Krichevsky O,Altan-Bonnet G
13-7021 was used in an ELISA assay to investigate how T cells produce cytokines as a function of antigen input.
Wed Apr 09 00:00:00 EDT 2014
CD28-inducible transcription factor DEC1 is required for efficient autoreactive CD4+ T cell response.
The Journal of experimental medicine
Martínez-Llordella M,Esensten JH,Bailey-Bucktrout SL,Lipsky RH,Marini A,Chen J,Mughal M,Mattson MP,Taub DD,Bluestone JA
13-7021 was used in an ELISA assay to identify DEC1 as a critical transcriptional mediator in the activation of naive CD4(+) T cells that is required for the development of a T cell-mediated autoimmune disease.
Mon Jul 29 00:00:00 EDT 2013
CD28-inducible transcription factor DEC1 is required for efficient autoreactive CD4+ T cell response.
The Journal of experimental medicine
Martínez-Llordella M,Esensten JH,Bailey-Bucktrout SL,Lipsky RH,Marini A,Chen J,Mughal M,Mattson MP,Taub DD,Bluestone JA
13-7021 was used in an ELISA assay to identify DEC1 as a critical transcriptional mediator in the activation of naive CD4(+) T cells that is required for the development of a T cell-mediated autoimmune disease.
Mon Jul 29 00:00:00 EDT 2013
Shaping T cell - B cell collaboration in the response to human immunodeficiency virus type 1 envelope glycoprotein gp120 by peptide priming.
PloS one
Steede NK,Rust BJ,Hossain MM,Freytag LC,Robinson JE,Landry SJ
13-7021 was used in an ELISpot assay to investigate how dominant B-cell subsets recruit the dominant T-cell subsets and that T-B collaborations can be shaped by epitope-specific priming.
Thu Jan 16 00:00:00 EST 2014
A role for IL-27 in limiting T regulatory cell populations.
Journal of immunology (Baltimore, Md. : 1950)
Wojno ED,Hosken N,Stumhofer JS,O'Hara AC,Mauldin E,Fang Q,Turka LA,Levin SD,Hunter CA
13-7021 was used in an ELISA assay to show that mice that overexpress IL-27 had decreased Treg frequencies and developed spontaneous inflammation.
Fri Jul 01 00:00:00 EDT 2011
CD8+CD122+ regulatory T cells (Tregs) and CD4+ Tregs cooperatively prevent and cure CD4+ cell-induced colitis.
Journal of immunology (Baltimore, Md. : 1950)
Endharti AT,Okuno Y,Shi Z,Misawa N,Toyokuni S,Ito M,Isobe K,Suzuki H
13-7021 was used in Flow cytometry/Cell sorting to investigate the role of CD8(+)CD122(+) regulatory T cells (Tregs) in maintenance of immune homeostasis, showing that CD8(+)CD122(+) Tregs and CD4+ Tregs cooperatively prevent and cure CD4+ cell-induced colitis.
Sat Jan 01 00:00:00 EST 2011
Immune responses to coiled coil supramolecular biomaterials.
Biomaterials
Rudra JS,Tripathi PK,Hildeman DA,Jung JP,Collier JH
13-7021 was used in an ELISA assay to investigate murine immune responses to a set of self-oligomerization assembled biomaterials.
Mon Nov 01 00:00:00 EDT 2010
Single-cell quantification of IL-2 response by effector and regulatory T cells reveals critical plasticity in immune response.
Molecular systems biology
Feinerman O,Jentsch G,Tkach KE,Coward JW,Hathorn MM,Sneddon MW,Emonet T,Smith KA,Altan-Bonnet G
13-7021 was used in an ELISA assay to demonstrate quantitative, experimentally validated predictions for the manipulation of T(reg) suppression.
Tue Nov 30 00:00:00 EST 2010
Estradiol-induced vaginal mucus inhibits antigen penetration and CD8(+) T cell priming in response to intravaginal immunization.
Vaccine
Seavey MM,Mosmann TR
13-7021 was used in an ELISpot assay to investigate the effect of estradiol during intravaginal immunisation, showing that estradiol-induced vaginal mucus inhibits antigen penetration and CD8(+) T cell priming.
Tue Apr 14 00:00:00 EDT 2009
Peripheral dendritic cells are essential for both the innate and adaptive antiviral immune responses in the central nervous system.
Virology
Steel CD,Hahto SM,Ciavarra RP
13-7021 was used in an ELISA assay to study the adaptive primary antiviral immune response in the CNS and the effect of dendritic cells upon this in vivo.
Sat Apr 25 00:00:00 EDT 2009
Automated analysis of two- and three-color fluorescent Elispot (Fluorospot) assays for cytokine secretion.
Computer methods and programs in biomedicine
Rebhahn JA,Bishop C,Divekar AA,Jiminez-Garcia K,Kobie JJ,Lee FE,Maupin GM,Snyder-Cappione JE,Zaiss DM,Mosmann TR
13-7021 was used in an ELISpot assay to develop an automated counting program to detect and quantify Fluorospots in automated fluorescence microscope images.
Wed Oct 01 00:00:00 EDT 2008
Automated analysis of two- and three-color fluorescent Elispot (Fluorospot) assays for cytokine secretion.
Computer methods and programs in biomedicine
Rebhahn JA,Bishop C,Divekar AA,Jiminez-Garcia K,Kobie JJ,Lee FE,Maupin GM,Snyder-Cappione JE,Zaiss DM,Mosmann TR
13-7021 was used in an ELISpot assay to develop an automated counting program to detect and quantify Fluorospots in automated fluorescence microscope images.
Wed Oct 01 00:00:00 EDT 2008
Automated analysis of two- and three-color fluorescent Elispot (Fluorospot) assays for cytokine secretion.
Computer methods and programs in biomedicine
Rebhahn JA,Bishop C,Divekar AA,Jiminez-Garcia K,Kobie JJ,Lee FE,Maupin GM,Snyder-Cappione JE,Zaiss DM,Mosmann TR
13-7021 was used in an ELISpot assay to develop an automated counting program to detect and quantify Fluorospots in automated fluorescence microscope images.
Wed Oct 01 00:00:00 EDT 2008
Automated analysis of two- and three-color fluorescent Elispot (Fluorospot) assays for cytokine secretion.
Computer methods and programs in biomedicine
Rebhahn JA,Bishop C,Divekar AA,Jiminez-Garcia K,Kobie JJ,Lee FE,Maupin GM,Snyder-Cappione JE,Zaiss DM,Mosmann TR
13-7021 was used in an ELISpot assay to develop an automated counting program to detect and quantify Fluorospots in automated fluorescence microscope images.
Wed Oct 01 00:00:00 EDT 2008
Modulation of pulmonary dendritic cell function during mycobacterial infection.
Infection and immunity
Anis MM,Fulton SA,Reba SM,Liu Y,Harding CV,Boom WH
13-7021 was used in an ELISA assay to investigate the role of chemokine receptor CCR7 and its ligands to activate naïve T cells during pulmonary infection.
Fri Feb 01 00:00:00 EST 2008
Modulation of naive CD4+ T-cell responses to an airway antigen during pulmonary mycobacterial infection.
Infection and immunity
Anis MM,Fulton SA,Reba SM,Harding CV,Boom WH
Published figure using IL-2 monoclonal antibody (Product # 13-7021-81) in ELISA
Tue May 01 00:00:00 EDT 2007
Macrophage-mediated but gamma interferon-independent innate immune responses control the primary wave of Plasmodium yoelii parasitemia.
Infection and immunity
Couper KN,Blount DG,Hafalla JC,van Rooijen N,de Souza JB,Riley EM
13-7021 was used in an ELISA assay to discern the factors that control the primary wave of plasmodium yoelii parasitaemia.
Sat Dec 01 00:00:00 EST 2007
Impaired selection of invariant natural killer T cells in diverse mouse models of glycosphingolipid lysosomal storage diseases.
The Journal of experimental medicine
Gadola SD,Silk JD,Jeans A,Illarionov PA,Salio M,Besra GS,Dwek R,Butters TD,Platt FM,Cerundolo V
13-7021 was used in an ELISA assay to investigate whether accumulation of glycosphingolipids in lysosomal storage diseases affects iNKT cell secretion or function.
Mon Oct 02 00:00:00 EDT 2006
Direct stimulation of T cells by membrane vesicles from antigen-presenting cells.
Proceedings of the National Academy of Sciences of the United States of America
Kovar M,Boyman O,Shen X,Hwang I,Kohler R,Sprent J
13-7021 was used in Flow cytometry/Cell sorting to study how dissociated cell membrane fragments from a DC line can be used as an effective substitute for viable DC.
Tue Aug 01 00:00:00 EDT 2006
Essential roles of CD8+CD122+ regulatory T cells in the maintenance of T cell homeostasis.
The Journal of experimental medicine
Rifa'i M,Kawamoto Y,Nakashima I,Suzuki H
13-7021 was used in Flow cytometry/Cell sorting to investigate the effect of transfer of CD8+CD122+ cells into CD122-deficient neonates, showing that CD8+CD122+ regulatory T cells are essential for T cell homeostasis.
Mon Nov 01 00:00:00 EST 2004
