Product References
Type H vessel/platelet-derived growth factor receptor β+ perivascular cell disintegration is involved in vascular injury and bone loss in radiation-induced bone damage.
Cell proliferation
Li J,Chen X,Ren L,Chen X,Wu T,Wang Y,Ren X,Cheng B,Xia J
Published figure using CD140b (PDGFRB) monoclonal antibody (Product # 14-1402-82) in Flow Cytometry
Sat Jul 01 00:00:00 EDT 2023
PD-L1-directed PlGF/VEGF blockade synergizes with chemotherapy by targeting CD141+ cancer-associated fibroblasts in pancreatic cancer.
Nature communications
Kim DK,Jeong J,Lee DS,Hyeon DY,Park GW,Jeon S,Lee KB,Jang JY,Hwang D,Kim HM,Jung K
14-1402-82 was used in Immunohistochemistry to study the mechanism underlying chemotherapy-induced fibrosis in PDAC.
Sat Oct 22 00:00:00 EDT 2022
Cancer cell autophagy, reprogrammed macrophages, and remodeled vasculature in glioblastoma triggers tumor immunity.
Cancer cell
Chryplewicz A,Scotton J,Tichet M,Zomer A,Shchors K,Joyce JA,Homicsko K,Hanahan D
14-1402-82 was used in Western Blot, Flow Cytometry, Immunohistochemistry (Frozen) to assess this concept by combining vascular endothelial growth factor (VEGF) pathway inhibitors that remodel the tumor vasculature with the tricyclic antidepressant imipramine, which enhances autophagy in GBM cancer cells and unexpectedly reprograms immunosuppressive tumor-associated macrophages via inhibition of histamine receptor signaling to become immunostimulatory.
Mon Oct 10 00:00:00 EDT 2022
Immature Vascular Smooth Muscle Cells in Healthy Murine Arteries and Atherosclerotic Plaques: Localization and Activity.
International journal of molecular sciences
Balatskiy A,Ozhimalov I,Balatskaya M,Savina A,Filatova J,Kalinina N,Popov V,Tkachuk V
14-1402-82 was used in Immunohistochemistry-immunofluorescence to oppose the hypothesis that immature VSMCs are directly involved in the formation of atherosclerotic lesions.
Thu Feb 03 00:00:00 EST 2022
Essential Roles of Exocyst Complex Component 3-like 2 on Cardiovascular Development in Mice.
Life (Basel, Switzerland)
Watanabe C,Shibuya H,Ichiyama Y,Okamura E,Tsukiyama-Fujii S,Tsukiyama T,Matsumoto S,Matsushita J,Azami T,Kubota Y,Ohji M,Sugiyama F,Takahashi S,Mizuno S,Tamura M,Mizutani KI,Ema M
14-1402-82 was used in Flow Cytometry, Immunohistochemistry (Frozen) to reveal that Exoc3l2 is essential for cardiovascular and brain development in mice.
Fri Oct 28 00:00:00 EDT 2022
Role of pericytes in the development of cerebral cavernous malformations.
iScience
Dai Z,Li J,Li Y,Wang R,Yan H,Xiong Z,Wu S,Yang X,Lu D,Zhang D,Li G,Wang Y,Men C,Du W,Zheng X,Shi C
14-1402-82 was used in Flow Cytometry, Immunohistochemistry (Frozen) to indicate that pericytes are essential for CCM lesion development, and fibronectin intervention may provide a novel target for therapeutic intervention in such patients.
Thu Dec 22 00:00:00 EST 2022
Three-axis classification of mouse lung mesenchymal cells reveals two populations of myofibroblasts.
Development (Cambridge, England)
Narvaez Del Pilar O,Gacha Garay MJ,Chen J
14-1402-82 was used in Immunohistochemistry-immunofluorescence to classify the mouse lung mesenchyme into three proximal-distal axes that are associated with the endothelium, epithelium and interstitium, respectively.
Tue Mar 15 00:00:00 EDT 2022
Mfsd2b and Spns2 are essential for maintenance of blood vessels during development and in anaphylactic shock.
Cell reports
Le TNU,Nguyen TQ,Kalailingam P,Nguyen YTK,Sukumar VK,Tan CKH,Tukijan F,Couty L,Hasan Z,Del Gaudio I,Wenk MR,Cazenave-Gassiot A,Camerer E,Nguyen LN
14-1402-82 was used in Immunohistochemistry to show that S1P export from Mfsd2b and Spns2 is essential for developing and mature vasculature.
Tue Aug 16 00:00:00 EDT 2022
Continuous sensing of IFNα by hepatic endothelial cells shapes a vascular antimetastatic barrier.
eLife
Tran NL,Ferreira LM,Alvarez-Moya B,Buttiglione V,Ferrini B,Zordan P,Monestiroli A,Fagioli C,Bezzecchi E,Scotti GM,Esposito A,Leone R,Gnasso C,Brendolan A,Guidotti LG,Sitia G
14-1402-82 was used in Flow Cytometry, Immunohistochemistry (Frozen) to demonstrate that the continuous infusion of therapeutic doses of interferon-alpha (IFNα) controls CRC invasion by acting on hepatic endothelial cells (HECs).
Tue Oct 25 00:00:00 EDT 2022
Release of stem cells from quiescence reveals gliogenic domains in the adult mouse brain.
Science (New York, N.Y.)
Delgado AC,Maldonado-Soto AR,Silva-Vargas V,Mizrak D,von Känel T,Tan KR,Paul A,Madar A,Cuervo H,Kitajewski J,Lin CS,Doetsch F
14-1402-82 was used in Immunohistochemistry to show that platelet-derived growth factor receptor beta (PDGFRβ) is expressed by adult ventricular-subventricular zone neural stem cells that generate olfactory bulb interneurons and glia.
Fri Jun 11 00:00:00 EDT 2021
Heterogeneous bone-marrow stromal progenitors drive myelofibrosis via a druggable alarmin axis.
Cell stem cell
Leimkühler NB,Gleitz HFE,Ronghui L,Snoeren IAM,Fuchs SNR,Nagai JS,Banjanin B,Lam KH,Vogl T,Kuppe C,Stalmann USA,Büsche G,Kreipe H,Gütgemann I,Krebs P,Banz Y,Boor P,Tai EW,Brümmendorf TH,Koschmieder S,Crysandt M,Bindels E,Kramann R,Costa IG,Schneider RK
14-1402-82 was used in Flow Cytometry to develop a comprehensive map of the stroma in myeloproliferative neoplasms (MPNs)on a single-cell level in murine models and patient samples.
Thu Apr 01 00:00:00 EDT 2021
Blockade of the CD93 pathway normalizes tumor vasculature to facilitate drug delivery and immunotherapy.
Science translational medicine
Sun Y,Chen W,Torphy RJ,Yao S,Zhu G,Lin R,Lugano R,Miller EN,Fujiwara Y,Bian L,Zheng L,Anand S,Gao F,Zhang W,Ferrara SE,Goodspeed AE,Dimberg A,Wang XJ,Edil BH,Barnett CC,Schulick RD,Chen L,Zhu Y
14-1402-82 was used in Immunohistochemistry to identify a molecular interaction involved in tumor vascular dysfunction and reveal an approach to promote a favorable tumor microenvironment for therapeutic intervention.
Wed Jul 28 00:00:00 EDT 2021
Cellular dormancy in minimal residual disease following targeted therapy.
Breast cancer research : BCR
Ruth JR,Pant DK,Pan TC,Seidel HE,Baksh SC,Keister BA,Singh R,Sterner CJ,Bakewell SJ,Moody SE,Belka GK,Chodosh LA
Published figure using CD140b (PDGFRB) monoclonal antibody (Product # 14-1402-82) in Flow Cytometry
Fri Jun 04 00:00:00 EDT 2021
Distinct Fibroblast Lineages Give Rise to NG2+ Pericyte Populations in Mouse Skin Development and Repair.
Frontiers in cell and developmental biology
Goss G,Rognoni E,Salameti V,Watt FM
Published figure using CD140b (PDGFRB) monoclonal antibody (Product # 14-1402-82) in Flow Cytometry
Wed Mar 02 00:00:00 EST 2022
Generation and characterization of a Myh6-driven Cre knockin mouse line.
Transgenic research
Huang X,Yan L,Kou S,Meng J,Lu Z,Lin CP,Liu C,Zhang H
14-1402-82 was used in Flow Cytometry, Immunohistochemistry (Frozen) to generate a Myh6-Cre knockin mouse model by inserting the IRES-Cre-wpre-polyA cassette between the translational stop codon and the 3' untranslated region of the endogenous Myh6 gene.
Wed Dec 01 00:00:00 EST 2021
Generation and characterization of a Myh6-driven Cre knockin mouse line.
Transgenic research
Huang X,Yan L,Kou S,Meng J,Lu Z,Lin CP,Liu C,Zhang H
14-1402-82 was used in Flow Cytometry, Immunohistochemistry (Frozen) to generate a Myh6-Cre knockin mouse model by inserting the IRES-Cre-wpre-polyA cassette between the translational stop codon and the 3' untranslated region of the endogenous Myh6 gene.
Wed Dec 01 00:00:00 EST 2021
Direct contribution of skeletal muscle mesenchymal progenitors to bone repair.
Nature communications
Julien A,Kanagalingam A,Martínez-Sarrà E,Megret J,Luka M,Ménager M,Relaix F,Colnot C
Published figure using CD140b (PDGFRB) monoclonal antibody (Product # 14-1402-82) in Immunohistochemistry
Mon May 17 00:00:00 EDT 2021
Perivascular cell-derived extracellular vesicles stimulate colorectal cancer revascularization after withdrawal of antiangiogenic drugs.
Journal of extracellular vesicles
Huang M,Chen M,Qi M,Ye G,Pan J,Shi C,Yang Y,Zhao L,Mo X,Zhang Y,Li Y,Zhong J,Lu W,Li X,Zhang J,Lin J,Luo L,Liu T,Tang PM,Hong A,Cao Y,Ye W,Zhang D
14-1402 was used in Immunocytochemistry-immunoflourescence to shed new mechanistic insights into perivascular cells in off-AA-TKI-induced tumour revascularization and indicate that blocking the Axl signalling may provide an attractive anticancer approach for sustaining long-lasting angiostatic effects to improve the therapeutic outcomes of antiangiogenic drugs in CRC.
Sat May 01 00:00:00 EDT 2021
Perivascular cell-derived extracellular vesicles stimulate colorectal cancer revascularization after withdrawal of antiangiogenic drugs.
Journal of extracellular vesicles
Huang M,Chen M,Qi M,Ye G,Pan J,Shi C,Yang Y,Zhao L,Mo X,Zhang Y,Li Y,Zhong J,Lu W,Li X,Zhang J,Lin J,Luo L,Liu T,Tang PM,Hong A,Cao Y,Ye W,Zhang D
14-1402 was used in Immunocytochemistry-immunoflourescence to shed new mechanistic insights into perivascular cells in off-AA-TKI-induced tumour revascularization and indicate that blocking the Axl signalling may provide an attractive anticancer approach for sustaining long-lasting angiostatic effects to improve the therapeutic outcomes of antiangiogenic drugs in CRC.
Sat May 01 00:00:00 EDT 2021
Cardiac pericytes function as key vasoactive cells to regulate homeostasis and disease.
FEBS open bio
Lee LL,Khakoo AY,Chintalgattu V
Published figure using CD140b (PDGFRB) monoclonal antibody (Product # 14-1402-82) in Flow Cytometry
Fri Jan 01 00:00:00 EST 2021
Optical manipulation of local cerebral blood flow in the deep brain of freely moving mice.
Cell reports
Abe Y,Kwon S,Oishi M,Unekawa M,Takata N,Seki F,Koyama R,Abe M,Sakimura K,Masamoto K,Tomita Y,Okano H,Mushiake H,Tanaka KF
14-1402-82 was used in Cell Culture to conclude that the development of vascular optogenetic animal models will help accelerate research linking vasculature, circuits, and behavior to health and disease.
Tue Jul 27 00:00:00 EDT 2021
PDGFRb+ mesenchymal cells, but not NG2+ mural cells, contribute to cardiac fat.
Cell reports
Jiang Z,Feng T,Lu Z,Wei Y,Meng J,Lin CP,Zhou B,Liu C,Zhang H
14-1402-82 was used in Immunohistochemistry to demonstrate that PDGFRb+ MCs, but not NG2+ coronary vascular mural cells, are the major source of intramyocardial adipocytes.
Tue Feb 02 00:00:00 EST 2021
Connectivity Mapping Identifies BI-2536 as a Potential Drug to Treat Diabetic Kidney Disease.
Diabetes
Zhang L,Wang Z,Liu R,Li Z,Lin J,Wojciechowicz ML,Huang J,Lee K,Ma'ayan A,He JC
14-1402-81 was used in Immunohistochemistry (Paraffin) to suggest that the PLK1 inhibitor BI-2536 should be further investigated as a novel therapy for DKD.
Mon Feb 01 00:00:00 EST 2021
Direct Tumor Killing and Immunotherapy through Anti-SerpinB9 Therapy.
Cell
Jiang L,Wang YJ,Zhao J,Uehara M,Hou Q,Kasinath V,Ichimura T,Banouni N,Dai L,Li X,Greiner DL,Shultz LD,Zhang X,Sun ZJ,Curtin I,Vangos NE,Yeoh ZC,Geffken EA,Seo HS,Liu ZX,Heffron GJ,Shah K,Dhe-Paganon S,Abdi R
14-1402-81 was used in Immunohistochemistry (Frozen) to describe a molecular target that permits a combination of tumor ablation, interference within the TME, and immunotherapy in one potential modality.
Wed Nov 25 00:00:00 EST 2020
Mosaic Mutant Analysis Identifies PDGFRα/PDGFRβ as Negative Regulators of Adipogenesis.
Cell stem cell
Sun C,Sakashita H,Kim J,Tang Z,Upchurch GM,Yao L,Berry WL,Griffin TM,Olson LE
14-1402-81 was used in Immunohistochemistry (Frozen) to show that both platelet-derived growth factor α and β receptors are cell-autonomous inhibitors of adipocyte differentiation and implicate downregulation of growth factor signalling as a critical event in the transition from adipocyte progenitors to adipocyte.
Thu May 07 00:00:00 EDT 2020
Single-cell profiling reveals an endothelium-mediated immunomodulatory pathway in the eye choroid.
The Journal of experimental medicine
Lehmann GL,Hanke-Gogokhia C,Hu Y,Bareja R,Salfati Z,Ginsberg M,Nolan DJ,Mendez-Huergo SP,Dalotto-Moreno T,Wojcinski A,Ochoa F,Zeng S,Cerliani JP,Panagis L,Zager PJ,Mullins RF,Ogura S,Lutty GA,Bang J,Zippin JH,Romano C,Rabinovich GA,Elemento O,Joyner AL,Rafii S,Rodriguez-Boulan E,Benedicto I
Published figure using CD140b (PDGFRB) monoclonal antibody (Product # 14-1402-82) in Immunocytochemistry
Mon Jun 01 00:00:00 EDT 2020
Single-cell profiling reveals an endothelium-mediated immunomodulatory pathway in the eye choroid.
The Journal of experimental medicine
Lehmann GL,Hanke-Gogokhia C,Hu Y,Bareja R,Salfati Z,Ginsberg M,Nolan DJ,Mendez-Huergo SP,Dalotto-Moreno T,Wojcinski A,Ochoa F,Zeng S,Cerliani JP,Panagis L,Zager PJ,Mullins RF,Ogura S,Lutty GA,Bang J,Zippin JH,Romano C,Rabinovich GA,Elemento O,Joyner AL,Rafii S,Rodriguez-Boulan E,Benedicto I
Published figure using CD140b (PDGFRB) monoclonal antibody (Product # 14-1402-82) in Immunocytochemistry
Mon Jun 01 00:00:00 EDT 2020
AP-2β/KCTD1 Control Distal Nephron Differentiation and Protect against Renal Fibrosis.
Developmental cell
Marneros AG
14-1402-82 was used in Immunohistochemistry to show that the transcription factor AP-2β is required for the differentiation of distal tubule precursors into early stage distal convoluted tubules during nephrogenesis.
Mon Aug 10 00:00:00 EDT 2020
Sphingosine 1-Phosphate Receptor Signaling Establishes AP-1 Gradients to Allow for Retinal Endothelial Cell Specialization.
Developmental cell
Yanagida K,Engelbrecht E,Niaudet C,Jung B,Gaengel K,Holton K,Swendeman S,Liu CH,Levesque MV,Kuo A,Fu Z,Smith LEH,Betsholtz C,Hla T
14-1402 was used in Immunohistochemistry to show that retinal endothelial sphingosine 1-phosphate receptors (S1PRs), which restrain vascular endothelial growth factor (VEGF)-induced angiogenesis, spatially restrict expression of JunB, a member of the activator protein 1 (AP-1) family of transcription factors (TFs).
Mon Mar 23 00:00:00 EDT 2020
Generation of diffuse intrinsic pontine glioma mouse models by brainstem-targeted in utero electroporation.
Neuro-oncology
Patel SK,Hartley RM,Wei X,Furnish R,Escobar-Riquelme F,Bear H,Choi K,Fuller C,Phoenix TN
14-1402 was used in Immunohistochemistry to generate new mouse models of diffuse intrinsic pontine gliomas (DIPGs) and characterize the role of specific oncogenic combinations in DIPG pathogenesis.
Thu Mar 05 00:00:00 EST 2020
Effects of Heterozygous TfR1 (Transferrin Receptor 1) Deletion in Pathogenesis of Renal Fibrosis in Mice.
Hypertension (Dallas, Tex. : 1979)
Yasumura S,Naito Y,Okuno K,Sawada H,Asakura M,Masuyama T,Ishihara M
14-1402 was used in Immunohistochemistry-immunofluorescence to suggest that TfR1 plays an important role in the development of renal fibrosis.
Sat Feb 01 00:00:00 EST 2020
Parenchymal pericytes are not the major contributor of extracellular matrix in the fibrotic scar after stroke in male mice.
Journal of neuroscience research
Roth M,Enström A,Aghabeick C,Carlsson R,Genové G,Paul G
14-1402 was used in Immunohistochemistry-immunofluorescence to suggest that parenchymal (PDGFRß+) pericytes do not play a dominant role in extracellular matrix formation in the fibrotic scar after stroke in male mice.
Fri May 01 00:00:00 EDT 2020
TGFβ1 orchestrates renal fibrosis following Escherichia coli pyelonephritis.
Physiological reports
Hreha TN,Collins CA,Daugherty AL,Twentyman J,Paluri N,Hunstad DA
14-1402-82 was used in Immunohistochemistry to increases in cortical populations of MSC-like cells and the Gli1 + activated myofibroblasts that are responsible for scarring.
Sun Mar 01 00:00:00 EST 2020
TGFβ1 orchestrates renal fibrosis following Escherichia coli pyelonephritis.
Physiological reports
Hreha TN,Collins CA,Daugherty AL,Twentyman J,Paluri N,Hunstad DA
14-1402-82 was used in Immunohistochemistry to increases in cortical populations of MSC-like cells and the Gli1 + activated myofibroblasts that are responsible for scarring.
Sun Mar 01 00:00:00 EST 2020
Angiomodulin (IGFBP7) is a cerebral specific angiocrine factor, but is probably not a blood-brain barrier inducer.
Fluids and barriers of the CNS
Bar O,Gelb S,Atamny K,Anzi S,Ben-Zvi A
Published figure using CD140b (PDGFRB) monoclonal antibody (Product # 14-1402-82) in Immunocytochemistry
Wed Apr 01 00:00:00 EDT 2020
Angiomodulin (IGFBP7) is a cerebral specific angiocrine factor, but is probably not a blood-brain barrier inducer.
Fluids and barriers of the CNS
Bar O,Gelb S,Atamny K,Anzi S,Ben-Zvi A
Published figure using CD140b (PDGFRB) monoclonal antibody (Product # 14-1402-82) in Immunocytochemistry
Wed Apr 01 00:00:00 EDT 2020
Macrophages promote endothelial-to-mesenchymal transition via MT1-MMP/TGFβ1 after myocardial infarction.
eLife
Alonso-Herranz L,Sahún-Español Á,Paredes A,Gonzalo P,Gkontra P,Núñez V,Clemente C,Cedenilla M,Villalba-Orero M,Inserte J,García-Dorado D,Arroyo AG,Ricote M
14-1402-82 was used in Immunocytochemistry to indicate the contribution of EndMT to cardiac fibrosis and adverse remodeling post-MI and identify Mφ MT1-MMP as a key regulator of this process.
Fri Oct 16 00:00:00 EDT 2020
Macrophages promote endothelial-to-mesenchymal transition via MT1-MMP/TGFβ1 after myocardial infarction.
eLife
Alonso-Herranz L,Sahún-Español Á,Paredes A,Gonzalo P,Gkontra P,Núñez V,Clemente C,Cedenilla M,Villalba-Orero M,Inserte J,García-Dorado D,Arroyo AG,Ricote M
14-1402-82 was used in Immunocytochemistry to indicate the contribution of EndMT to cardiac fibrosis and adverse remodeling post-MI and identify Mφ MT1-MMP as a key regulator of this process.
Fri Oct 16 00:00:00 EDT 2020
Gliomas Interact with Non-glioma Brain Cells via Extracellular Vesicles.
Cell reports
Gao X,Zhang Z,Mashimo T,Shen B,Nyagilo J,Wang H,Wang Y,Liu Z,Mulgaonkar A,Hu XL,Piccirillo SGM,Eskiocak U,Davé DP,Qin S,Yang Y,Sun X,Fu YX,Zong H,Sun W,Bachoo RM,Ge WP
14-1402-81 was used in Immunocytochemistry to indicate that EV-mediated interaction between glioma cells and non-glioma brain cells alters the tumor microenvironment and contributes to glioma development.
Tue Feb 25 00:00:00 EST 2020
Non-neuronal expression of SARS-CoV-2 entry genes in the olfactory system suggests mechanisms underlying COVID-19-associated anosmia.
Science advances
Brann DH,Tsukahara T,Weinreb C,Lipovsek M,Van den Berge K,Gong B,Chance R,Macaulay IC,Chou HJ,Fletcher RB,Das D,Street K,de Bezieux HR,Choi YG,Risso D,Dudoit S,Purdom E,Mill J,Hachem RA,Matsunami H,Logan DW,Goldstein BJ,Grubb MS,Ngai J,Datta SR
14-1402 was used in Western Blotting to identify cell types in the olfactory epithelium and olfactory bulb that express SARS-CoV-2 cell entry molecules.
Fri Jul 31 00:00:00 EDT 2020
Arterial Sca1+ Vascular Stem Cells Generate De Novo Smooth Muscle for Artery Repair and Regeneration.
Cell stem cell
Tang J,Wang H,Huang X,Li F,Zhu H,Li Y,He L,Zhang H,Pu W,Liu K,Zhao H,Bentzon JF,Yu Y,Ji Y,Nie Y,Tian X,Zhang L,Gao D,Zhou B
14-1402-81 was used in Immunocytochemistry to identify Sca1+ VSCs in the adventitial layer of artery walls.
Thu Jan 02 00:00:00 EST 2020
Profiling the mouse brain endothelial transcriptome in health and disease models reveals a core blood-brain barrier dysfunction module.
Nature neuroscience
Munji RN,Soung AL,Weiner GA,Sohet F,Semple BD,Trivedi A,Gimlin K,Kotoda M,Korai M,Aydin S,Batugal A,Cabangcala AC,Schupp PG,Oldham MC,Hashimoto T,Noble-Haeusslein LJ,Daneman R
14-1402 was used in Immunohistochemistry to analyse the gene expression of endothelial cells in mice, comparing brain endothelial cells with peripheral endothelial cells.
Fri Nov 01 00:00:00 EDT 2019
Expression Profiling of Fibroblasts in Chronic and Acute Disease Models Reveals Novel Pathways in Kidney Fibrosis.
Journal of the American Society of Nephrology : JASN
Higashi AY,Aronow BJ,Dressler GR
14-1402 was used in Immunohistochemistry to investigate whether activated fibroblasts demonstrate changes in gene expression that correspond with regression after acute injury but are not observed in chronic models of fibrosis.
Tue Jan 01 00:00:00 EST 2019
Dual functions of angiopoietin-like protein 2 signaling in tumor progression and anti-tumor immunity.
Genes & development
Horiguchi H,Kadomatsu T,Kurahashi R,Hara C,Miyata K,Baba M,Osumi H,Terada K,Araki K,Takai T,Kamba T,Linehan WM,Moroishi T,Oike Y
14-1402 was used in Immunohistochemistry-immunofluorescence to provide strong evidence that ANGPTL2 can function in either tumor promotion or suppression, depending on what cell type it is expressed in.
Sun Dec 01 00:00:00 EST 2019
Fibroblast mTOR/PPARγ/HGF axis protects against tubular cell death and acute kidney injury.
Cell death and differentiation
Gui Y,Lu Q,Gu M,Wang M,Liang Y,Zhu X,Xue X,Sun X,He W,Yang J,Zhao AZ,Xiao B,Dai C
14-1402 was used in Immunocytochemistry-Immunofluorescence to investigate mTOR signalling in fibroblasts during acute kidney injury.
Sun Dec 01 00:00:00 EST 2019
Vitronectin from brain pericytes promotes adult forebrain neurogenesis by stimulating CNTF.
Experimental neurology
Jia C,Keasey MP,Malone HM,Lovins C,Sante RR,Razskazovskiy V,Hagg T
14-1402-82 was used in Immunohistochemistry to investigate if vitronectin is uniquely expressed by approximately half of the pericytes of subventricular zone (SVZ) where neurogenesis continues throughout life.
Fri Feb 01 00:00:00 EST 2019
STAT3 Inhibition Partly Abolishes IL-33-Induced Bone Marrow-Derived Monocyte Phenotypic Transition into Fibroblast Precursor and Alleviates Experimental Renal Interstitial Fibrosis.
Journal of immunology (Baltimore, Md. : 1950)
Zhu F,Bai X,Hong Q,Cui S,Wang X,Xiao F,Li J,Zhang L,Dong Z,Wang Y,Cai G,Chen X
14-1402 was used in Immunohistochemistry to determine that the STAT3 inhibitor BP-1-102 alleviates renal interstitial fibrosis by inhibiting bone marrow-derived monocyte transition into fibroblast precursors in an IL-33/STAT3-dependent manner.
Fri Nov 15 00:00:00 EST 2019
Standard screening methods underreport AAV-mediated transduction and gene editing.
Nature communications
Lang JF,Toulmin SA,Brida KL,Eisenlohr LC,Davidson BL
Published figure using CD140b (PDGFRB) monoclonal antibody (Product # 14-1402-82) in Immunohistochemistry
Tue Jul 30 00:00:00 EDT 2019
Claudin-12 is not required for blood-brain barrier tight junction function.
Fluids and barriers of the CNS
Castro Dias M,Coisne C,Baden P,Enzmann G,Garrett L,Becker L,Hölter SM,Hrabě de Angelis M,Deutsch U,Engelhardt B
Published figure using CD140b (PDGFRB) monoclonal antibody (Product # 14-1402-82) in Immunofluorescence
Thu Sep 12 00:00:00 EDT 2019
Claudin-12 is not required for blood-brain barrier tight junction function.
Fluids and barriers of the CNS
Castro Dias M,Coisne C,Baden P,Enzmann G,Garrett L,Becker L,Hölter SM,Hrabě de Angelis M,Deutsch U,Engelhardt B
Published figure using CD140b (PDGFRB) monoclonal antibody (Product # 14-1402-82) in Immunofluorescence
Thu Sep 12 00:00:00 EDT 2019
Dual lineage tracing identifies intermediate mesenchymal stage for endocardial contribution to fibroblasts, coronary mural cells, and adipocytes.
The Journal of biological chemistry
Huang X,Feng T,Jiang Z,Meng J,Kou S,Lu Z,Chen W,Lin CP,Zhou B,Zhang H
Published figure using CD140b (PDGFRB) monoclonal antibody (Product # 14-1402-82) in Flow Cytometry
Fri May 31 00:00:00 EDT 2019
Dual lineage tracing identifies intermediate mesenchymal stage for endocardial contribution to fibroblasts, coronary mural cells, and adipocytes.
The Journal of biological chemistry
Huang X,Feng T,Jiang Z,Meng J,Kou S,Lu Z,Chen W,Lin CP,Zhou B,Zhang H
Published figure using CD140b (PDGFRB) monoclonal antibody (Product # 14-1402-82) in Flow Cytometry
Fri May 31 00:00:00 EDT 2019
Dual lineage tracing identifies intermediate mesenchymal stage for endocardial contribution to fibroblasts, coronary mural cells, and adipocytes.
The Journal of biological chemistry
Huang X,Feng T,Jiang Z,Meng J,Kou S,Lu Z,Chen W,Lin CP,Zhou B,Zhang H
Published figure using CD140b (PDGFRB) monoclonal antibody (Product # 14-1402-82) in Flow Cytometry
Fri May 31 00:00:00 EDT 2019
Spatiotemporally Dependent Vascularization Is Differently Utilized among Neural Progenitor Subtypes during Neocortical Development.
Cell reports
Komabayashi-Suzuki M,Yamanishi E,Watanabe C,Okamura M,Tabata H,Iwai R,Ajioka I,Matsushita J,Kidoya H,Takakura N,Okamoto T,Kinoshita K,Ichihashi M,Nagata KI,Ema M,Mizutani KI
Tue Oct 29 00:00:00 EDT 2019
Growth Factor Screening in Dystrophic Muscles Reveals PDGFB/PDGFRB-Mediated Migration of Interstitial Stem Cells.
International journal of molecular sciences
Camps J,Grosemans H,Gijsbers R,Maes C,Sampaolesi M
Published figure using CD140b (PDGFRB) monoclonal antibody (Product # 14-1402-82) in Flow Cytometry
Tue Mar 05 00:00:00 EST 2019
1,25(OH)2D3 regulates the proangiogenic activity of pericyte through VDR-mediated modulation of VEGF production and signaling of VEGF and PDGF receptors.
FASEB bioAdvances
Jamali N,Song YS,Sorenson CM,Sheibani N
14-1402 was used in Flow cytometry/Cell sorting to determine the impact of 1,25(OH)2D3 on retinal pericytes prepared from wild type and VDR-deficient mice.
Mon Jul 01 00:00:00 EDT 2019
Circuit Design Features of a Stable Two-Cell System.
Cell
Zhou X,Franklin RA,Adler M,Jacox JB,Bailis W,Shyer JA,Flavell RA,Mayo A,Alon U,Medzhitov R
14-1402 was used in Flow cytometry/Cell sorting to illustrate principles of cell circuit design and provide a quantitative perspective on cell interactions.
Thu Feb 08 00:00:00 EST 2018
A dual genetic tracing system identifies diverse and dynamic origins of cardiac valve mesenchyme.
Development (Cambridge, England)
Liu K,Yu W,Tang M,Tang J,Liu X,Liu Q,Li Y,He L,Zhang L,Evans SM,Tian X,Lui KO,Zhou B
14-1402 was used in Immunohistochemistry to provide a proof-of-principle application of the Nigri-nox system for in vivo mouse genomic engineering.
Mon Sep 17 00:00:00 EDT 2018
Molecular mechanisms of IL-33-mediated stromal interactions in cancer metastasis.
JCI insight
Andersson P,Yang Y,Hosaka K,Zhang Y,Fischer C,Braun H,Liu S,Yu G,Liu S,Beyaert R,Chang M,Li Q,Cao Y
14-1402 was used in Flow cytometry/Cell sorting to study the IL-33-NF-κB-MMP9-laminin axis that mediates the cancer-associated fibroblast-tumour-associated macrophage-committed cancer metastasis.
Thu Oct 18 00:00:00 EDT 2018
Molecular mechanisms of IL-33-mediated stromal interactions in cancer metastasis.
JCI insight
Andersson P,Yang Y,Hosaka K,Zhang Y,Fischer C,Braun H,Liu S,Yu G,Liu S,Beyaert R,Chang M,Li Q,Cao Y
14-1402 was used in Flow cytometry/Cell sorting to study the IL-33-NF-κB-MMP9-laminin axis that mediates the cancer-associated fibroblast-tumour-associated macrophage-committed cancer metastasis.
Thu Oct 18 00:00:00 EDT 2018
Dual roles of endothelial FGF-2-FGFR1-PDGF-BB and perivascular FGF-2-FGFR2-PDGFRβ signaling pathways in tumor vascular remodeling.
Cell discovery
Hosaka K,Yang Y,Nakamura M,Andersson P,Yang X,Zhang Y,Seki T,Scherzer M,Dubey O,Wang X,Cao Y
14-1402 was used in Immunocytochemistry-immunoflourescence to identify a novel mechanism by which FGF-2 and PDGF-BB collaboratively modulate perivascular cell coverage in tumour vessels.
Mon Mar 21 00:00:00 EDT 2022
A molecular atlas of cell types and zonation in the brain vasculature.
Nature
Vanlandewijck M,He L,Mäe MA,Andrae J,Ando K,Del Gaudio F,Nahar K,Lebouvier T,Laviña B,Gouveia L,Sun Y,Raschperger E,Räsänen M,Zarb Y,Mochizuki N,Keller A,Lendahl U,Betsholtz C
14-1402-82 was used in Flow Cytometry, Immunohistochemistry (Frozen) to illustrate the power of single-cell transcriptomics to decode the higher organizational principles of a tissue and may provide the initial chapter in a molecular encyclopaedia of the mammalian vasculature.
Thu Feb 22 00:00:00 EST 2018
Pulmonary pericytes regulate lung morphogenesis.
Nature communications
Kato K,Diéguez-Hurtado R,Park DY,Hong SP,Kato-Azuma S,Adams S,Stehling M,Trappmann B,Wrana JL,Koh GY,Adams RH
14-1402 was used in Immunohistochemistry to establish that pericytes coordinate the behavior of epithelial and vascular cells during lung morphogenesis.
Fri Jun 22 00:00:00 EDT 2018
Pulmonary pericytes regulate lung morphogenesis.
Nature communications
Kato K,Diéguez-Hurtado R,Park DY,Hong SP,Kato-Azuma S,Adams S,Stehling M,Trappmann B,Wrana JL,Koh GY,Adams RH
14-1402 was used in Immunohistochemistry to establish that pericytes coordinate the behavior of epithelial and vascular cells during lung morphogenesis.
Fri Jun 22 00:00:00 EDT 2018
EphB2 receptor tyrosine kinase promotes hepatic fibrogenesis in mice via activation of hepatic stellate cells.
Scientific reports
Mimche PN,Lee CM,Mimche SM,Thapa M,Grakoui A,Henkemeyer M,Lamb TJ
14-1402 was used in Immunohistochemistry to identify that upregulation of EphB2 is a prominent feature of two mouse models of hepatic fibrosis and also observed in humans with liver cirrhosis.
Wed Feb 07 00:00:00 EST 2018
Prolonged systemic hyperglycemia does not cause pericyte loss and permeability at the mouse blood-brain barrier.
Scientific reports
Mäe MA,Li T,Bertuzzi G,Raschperger E,Vanlandewijck M,He L,Nahar K,Dalheim A,Hofmann JJ,Laviña B,Keller A,Betsholtz C,Genové G
14-1402 was used in Immunohistochemistry to study whether prolonged systemic hyperglycaemia induces blood-brain barrier dysfunction and leakage.
Thu Nov 29 00:00:00 EST 2018
Gpr124 is essential for blood-brain barrier integrity in central nervous system disease.
Nature medicine
Chang J,Mancuso MR,Maier C,Liang X,Yuki K,Yang L,Kwong JW,Wang J,Rao V,Vallon M,Kosinski C,Zhang JJ,Mah AT,Xu L,Li L,Gholamin S,Reyes TF,Li R,Kuhnert F,Han X,Yuan J,Chiou SH,Brettman AD,Daly L,Corney DC,Cheshier SH,Shortliffe LD,Wu X,Snyder M,Chan P,Giffard RG,Chang HY,Andreasson K,Kuo CJ
Sat Apr 01 00:00:00 EDT 2017
Fibroblasts in an endocardial fibroelastosis disease model mainly originate from mesenchymal derivatives of epicardium.
Cell research
Zhang H,Huang X,Liu K,Tang J,He L,Pu W,Liu Q,Li Y,Tian X,Wang Y,Zhang L,Yu Y,Wang H,Hu R,Wang F,Chen T,Wang QD,Qiao Z,Zhang L,Lui KO,Zhou B
14-1402 was used in Immunohistochemistry to examine the origin of the excessive fibroblasts found within endocardial fibroelastosis-like tissues.
Fri Sep 01 00:00:00 EDT 2017
A fluoro-Nissl dye identifies pericytes as distinct vascular mural cells during in vivo brain imaging.
Nature neuroscience
Damisah EC,Hill RA,Tong L,Murray KN,Grutzendler J
14-1402 was used in Immunohistochemistry to demonstrate the ability of NeuroTrace 500/525 to label brain pericytes with specificity, allowing high-resolution optical imaging in the live mouse.
Sat Jul 01 00:00:00 EDT 2017
Cardiac myofibroblast engulfment of dead cells facilitates recovery after myocardial infarction.
The Journal of clinical investigation
Nakaya M,Watari K,Tajima M,Nakaya T,Matsuda S,Ohara H,Nishihara H,Yamaguchi H,Hashimoto A,Nishida M,Nagasaka A,Horii Y,Ono H,Iribe G,Inoue R,Tsuda M,Inoue K,Tanaka A,Kuroda M,Nagata S,Kurose H
14140282 was used in immunohistochemistry - frozen section to observe that cardiac myofibroblasts efficiently engulf dead cells
Tue Jan 03 00:00:00 EST 2017
Repression of Interstitial Identity in Nephron Progenitor Cells by Pax2 Establishes the Nephron-Interstitium Boundary during Kidney Development.
Developmental cell
Naiman N,Fujioka K,Fujino M,Valerius MT,Potter SS,McMahon AP,Kobayashi A
Published figure using CD140b (PDGFRB) monoclonal antibody (Product # 14-1402-82) in Immunohistochemistry (Frozen)
Mon May 22 00:00:00 EDT 2017
Repression of Interstitial Identity in Nephron Progenitor Cells by Pax2 Establishes the Nephron-Interstitium Boundary during Kidney Development.
Developmental cell
Naiman N,Fujioka K,Fujino M,Valerius MT,Potter SS,McMahon AP,Kobayashi A
Published figure using CD140b (PDGFRB) monoclonal antibody (Product # 14-1402-82) in Immunohistochemistry (Frozen)
Mon May 22 00:00:00 EDT 2017
Repression of Interstitial Identity in Nephron Progenitor Cells by Pax2 Establishes the Nephron-Interstitium Boundary during Kidney Development.
Developmental cell
Naiman N,Fujioka K,Fujino M,Valerius MT,Potter SS,McMahon AP,Kobayashi A
Published figure using CD140b (PDGFRB) monoclonal antibody (Product # 14-1402-82) in Immunohistochemistry (Frozen)
Mon May 22 00:00:00 EDT 2017
Smooth muscle cell recruitment to lymphatic vessels requires PDGFB and impacts vessel size but not identity.
Development (Cambridge, England)
Wang Y,Jin Y,Mäe MA,Zhang Y,Ortsäter H,Betsholtz C,Mäkinen T,Jakobsson L
Published figure using CD140b (PDGFRB) monoclonal antibody (Product # 14-1402-82) in Immunofluorescence
Sun Oct 01 00:00:00 EDT 2017
Characterization of transgene expression and pDNA distribution of the suctioned kidney in mice.
Drug delivery
Oyama N,Fuchigami Y,Fumoto S,Sato M,Hagimori M,Shimizu K,Kawakami S
Wed Nov 01 00:00:00 EDT 2017
Imatinib Inhibits the Renewal and Tumorigenicity of CT-26 Colon Cancer Cells after Cytoreductive Treatment with Doxorubicin.
Archivum immunologiae et therapiae experimentalis
Przybyszewska M,Miłoszewska J,Kotlarz A,Swoboda P,Pyśniak K,Szczepek W,Kaczmarek Ł,Markowicz S
14140282 was used in flow cytometry to assess if drugs that target receptor tyrosine kinases silence or eliminate colorectal cancer cells that are refractory to conventional treatment
Wed Feb 01 00:00:00 EST 2017
Laminin differentially regulates the stemness of type I and type II pericytes.
Stem cell research & therapy
Gautam J,Nirwane A,Yao Y
14140282 was used in immunohistochemistry to examine the role of laminin on type I and type II pericyte proliferation and differentiation
Tue Feb 07 00:00:00 EST 2017
Laminin differentially regulates the stemness of type I and type II pericytes.
Stem cell research & therapy
Gautam J,Nirwane A,Yao Y
14140282 was used in immunohistochemistry to examine the role of laminin on type I and type II pericyte proliferation and differentiation
Tue Feb 07 00:00:00 EST 2017
Laminin differentially regulates the stemness of type I and type II pericytes.
Stem cell research & therapy
Gautam J,Nirwane A,Yao Y
14140282 was used in immunohistochemistry to examine the role of laminin on type I and type II pericyte proliferation and differentiation
Tue Feb 07 00:00:00 EST 2017
Pericytes regulate VEGF-induced endothelial sprouting through VEGFR1.
Nature communications
Eilken HM,Diéguez-Hurtado R,Schmidt I,Nakayama M,Jeong HW,Arf H,Adams S,Ferrara N,Adams RH
Published figure using CD140b (PDGFRB) monoclonal antibody (Product # 14-1402-82) in Immunohistochemistry
Fri Nov 17 00:00:00 EST 2017
Pericytes regulate VEGF-induced endothelial sprouting through VEGFR1.
Nature communications
Eilken HM,Diéguez-Hurtado R,Schmidt I,Nakayama M,Jeong HW,Arf H,Adams S,Ferrara N,Adams RH
Published figure using CD140b (PDGFRB) monoclonal antibody (Product # 14-1402-82) in Immunohistochemistry
Fri Nov 17 00:00:00 EST 2017
Neural Crest Cells Contribute an Astrocyte-like Glial Population to the Spleen.
Scientific reports
Barlow-Anacker AJ,Fu M,Erickson CS,Bertocchini F,Gosain A
14-1402 was used in Immunohistochemistry to demonstrate that neural crest cells (NCC) colonize the spleen during embryogenesis and persist into adulthood.
Tue Mar 28 00:00:00 EDT 2017
Neonatal pancreatic pericytes support β-cell proliferation.
Molecular metabolism
Epshtein A,Rachi E,Sakhneny L,Mizrachi S,Baer D,Landsman L
Published figure using CD140b (PDGFRB) monoclonal antibody (Product # 14-1402-82) in Flow Cytometry
Sun Oct 01 00:00:00 EDT 2017
A PPARγ transcriptional cascade directs adipose progenitor cell-niche interaction and niche expansion.
Nature communications
Jiang Y,Berry DC,Jo A,Tang W,Arpke RW,Kyba M,Graff JM
14-1402 was used in Immunohistochemistry to indicate that adipose progenitor cells direct adipose tissue niche expansion via a PPARγ-initiated PDGFRΒ and VEGF transcriptional axis.
Mon Jun 26 00:00:00 EDT 2017
Age-dependent modulation of vascular niches for haematopoietic stem cells.
Nature
Kusumbe AP,Ramasamy SK,Itkin T,Mäe MA,Langen UH,Betsholtz C,Lapidot T,Adams RH
Published figure using CD140b (PDGFRB) monoclonal antibody (Product # 14-1402-82) in Immunofluorescence
Thu Apr 21 00:00:00 EDT 2016
Age-dependent modulation of vascular niches for haematopoietic stem cells.
Nature
Kusumbe AP,Ramasamy SK,Itkin T,Mäe MA,Langen UH,Betsholtz C,Lapidot T,Adams RH
Published figure using CD140b (PDGFRB) monoclonal antibody (Product # 14-1402-82) in Immunofluorescence
Thu Apr 21 00:00:00 EDT 2016
Age-dependent modulation of vascular niches for haematopoietic stem cells.
Nature
Kusumbe AP,Ramasamy SK,Itkin T,Mäe MA,Langen UH,Betsholtz C,Lapidot T,Adams RH
Published figure using CD140b (PDGFRB) monoclonal antibody (Product # 14-1402-82) in Immunofluorescence
Thu Apr 21 00:00:00 EDT 2016
Age-dependent modulation of vascular niches for haematopoietic stem cells.
Nature
Kusumbe AP,Ramasamy SK,Itkin T,Mäe MA,Langen UH,Betsholtz C,Lapidot T,Adams RH
Published figure using CD140b (PDGFRB) monoclonal antibody (Product # 14-1402-82) in Immunofluorescence
Thu Apr 21 00:00:00 EDT 2016
Age-dependent modulation of vascular niches for haematopoietic stem cells.
Nature
Kusumbe AP,Ramasamy SK,Itkin T,Mäe MA,Langen UH,Betsholtz C,Lapidot T,Adams RH
Published figure using CD140b (PDGFRB) monoclonal antibody (Product # 14-1402-82) in Immunofluorescence
Thu Apr 21 00:00:00 EDT 2016
Medulloblastoma Genotype Dictates Blood Brain Barrier Phenotype.
Cancer cell
Phoenix TN,Patmore DM,Boop S,Boulos N,Jacus MO,Patel YT,Roussel MF,Finkelstein D,Goumnerova L,Perreault S,Wadhwa E,Cho YJ,Stewart CF,Gilbertson RJ
14-1402 was used in Immunofluorescence to demonstrate the biological basis of WNT-medulloblastoma treatment sensitivity: medulloblastoma genotype dictates tumour vessel phenotype, partially explaining disparate prognoses among subtypes.
Mon Apr 11 00:00:00 EDT 2016
Revisiting Cardiac Cellular Composition.
Circulation research
Pinto AR,Ilinykh A,Ivey MJ,Kuwabara JT,D'Antoni ML,Debuque R,Chandran A,Wang L,Arora K,Rosenthal NA,Tallquist MD
14-1402 was used in Immunofluorescence to examine the relative frequency of cardiac endothelial cells, hematopoietic-derived cells, and fibroblasts in the mouse and human heart.
Fri Feb 05 00:00:00 EST 2016
Distinct subpopulations of FOXD1 stroma-derived cells regulate renal erythropoietin.
The Journal of clinical investigation
Kobayashi H,Liu Q,Binns TC,Urrutia AA,Davidoff O,Kapitsinou PP,Pfaff AS,Olauson H,Wernerson A,Fogo AB,Fong GH,Gross KW,Haase VH
14-1402-82 was used in Magnetic cell separation to characterise the expression patterns of distinct subpopulations of FOXD1 stroma-derived cells in the liver responsible for erythropoietin regulation.
Mon May 02 00:00:00 EDT 2016
Paracrine Wnt1 Drives Interstitial Fibrosis without Inflammation by Tubulointerstitial Cross-Talk.
Journal of the American Society of Nephrology : JASN
Maarouf OH,Aravamudhan A,Rangarajan D,Kusaba T,Zhang V,Welborn J,Gauvin D,Hou X,Kramann R,Humphreys BD
Published figure using CD140b (PDGFRB) monoclonal antibody (Product # 14-1402-82) in Flow Cytometry
Tue Mar 01 00:00:00 EST 2016
Paracrine Wnt1 Drives Interstitial Fibrosis without Inflammation by Tubulointerstitial Cross-Talk.
Journal of the American Society of Nephrology : JASN
Maarouf OH,Aravamudhan A,Rangarajan D,Kusaba T,Zhang V,Welborn J,Gauvin D,Hou X,Kramann R,Humphreys BD
Published figure using CD140b (PDGFRB) monoclonal antibody (Product # 14-1402-82) in Flow Cytometry
Tue Mar 01 00:00:00 EST 2016
Epithelial cell integrin β1 is required for developmental angiogenesis in the pituitary gland.
Proceedings of the National Academy of Sciences of the United States of America
Scully KM,Skowronska-Krawczyk D,Krawczyk M,Merkurjev D,Taylor H,Livolsi A,Tollkuhn J,Stan RV,Rosenfeld MG
Published figure using CD140b (PDGFRB) monoclonal antibody (Product # 14-1402-82) in Immunofluorescence
Tue Nov 22 00:00:00 EST 2016
Islet Pericytes Are Required for β-Cell Maturity.
Diabetes
Sasson A,Rachi E,Sakhneny L,Baer D,Lisnyansky M,Epshtein A,Landsman L
14-1402 was used in Immunohistochemistry-immunofluorescence to suggest that pericytes are pivotal components of the islet niche, which are required for beta-cell maturity and functionality.
Sat Oct 01 00:00:00 EDT 2016
PDGF-A and PDGF-B induces cardiac fibrosis in transgenic mice.
Experimental cell research
Gallini R,Lindblom P,Bondjers C,Betsholtz C,Andrae J
14140282 was used in immunohistochemistry - paraffin section to characterize 3 transgenic mouse lines in which different platelet-derived growth factor ligands are expressed under the same heart specific promoter
Sat Dec 10 00:00:00 EST 2016
The role of pericytic laminin in blood brain barrier integrity maintenance.
Scientific reports
Gautam J,Zhang X,Yao Y
14140282 was used in immunohistochemistry to examine the function of pericyte-derived laminin in vascular integrity
Thu Nov 03 00:00:00 EDT 2016
The role of pericytic laminin in blood brain barrier integrity maintenance.
Scientific reports
Gautam J,Zhang X,Yao Y
14140282 was used in immunohistochemistry to examine the function of pericyte-derived laminin in vascular integrity
Thu Nov 03 00:00:00 EDT 2016
The role of pericytic laminin in blood brain barrier integrity maintenance.
Scientific reports
Gautam J,Zhang X,Yao Y
14140282 was used in immunohistochemistry to examine the function of pericyte-derived laminin in vascular integrity
Thu Nov 03 00:00:00 EDT 2016
Laminin regulates PDGFRβ(+) cell stemness and muscle development.
Nature communications
Yao Y,Norris EH,Mason CE,Strickland S
Published figure using CD140b (PDGFRB) monoclonal antibody (Product # 14-1402-82) in Immunofluorescence
Tue May 03 00:00:00 EDT 2016
Laminin regulates PDGFRβ(+) cell stemness and muscle development.
Nature communications
Yao Y,Norris EH,Mason CE,Strickland S
Published figure using CD140b (PDGFRB) monoclonal antibody (Product # 14-1402-82) in Immunofluorescence
Tue May 03 00:00:00 EDT 2016
Heterogeneous fibroblasts underlie age-dependent tertiary lymphoid tissues in the kidney.
JCI insight
Sato Y,Mii A,Hamazaki Y,Fujita H,Nakata H,Masuda K,Nishiyama S,Shibuya S,Haga H,Ogawa O,Shimizu A,Narumiya S,Kaisho T,Arita M,Yanagisawa M,Miyasaka M,Sharma K,Minato N,Kawamoto H,Yanagita M
Published figure using CD140b (PDGFRB) monoclonal antibody (Product # 14-1402-82) in Immunohistochemistry
Thu Jul 21 00:00:00 EDT 2016
The PDGF-BB-SOX7 axis-modulated IL-33 in pericytes and stromal cells promotes metastasis through tumour-associated macrophages.
Nature communications
Yang Y,Andersson P,Hosaka K,Zhang Y,Cao R,Iwamoto H,Yang X,Nakamura M,Wang J,Zhuang R,Morikawa H,Xue Y,Braun H,Beyaert R,Samani N,Nakae S,Hams E,Dissing S,Fallon PG,Langer R,Cao Y
Published figure using CD140b (PDGFRB) monoclonal antibody (Product # 14-1402-82) in Immunofluorescence
Fri May 06 00:00:00 EDT 2016
The PDGF-BB-SOX7 axis-modulated IL-33 in pericytes and stromal cells promotes metastasis through tumour-associated macrophages.
Nature communications
Yang Y,Andersson P,Hosaka K,Zhang Y,Cao R,Iwamoto H,Yang X,Nakamura M,Wang J,Zhuang R,Morikawa H,Xue Y,Braun H,Beyaert R,Samani N,Nakae S,Hams E,Dissing S,Fallon PG,Langer R,Cao Y
Published figure using CD140b (PDGFRB) monoclonal antibody (Product # 14-1402-82) in Immunofluorescence
Fri May 06 00:00:00 EDT 2016
Isoform-Specific Modulation of Inflammation Induced by Adenoviral Mediated Delivery of Platelet-Derived Growth Factors in the Adult Mouse Heart.
PloS one
Gallini R,Huusko J,Ylä-Herttuala S,Betsholtz C,Andrae J
Published figure using CD140b (PDGFRB) monoclonal antibody (Product # 14-1402-82) in Immunohistochemistry
Mon Aug 07 00:00:00 EDT 2017
Analysis of the brain mural cell transcriptome.
Scientific reports
He L,Vanlandewijck M,Raschperger E,Andaloussi Mäe M,Jung B,Lebouvier T,Ando K,Hofmann J,Keller A,Betsholtz C
Published figure using CD140b (PDGFRB) monoclonal antibody (Product # 14-1402-82) in Immunofluorescence
Tue Oct 11 00:00:00 EDT 2016
Analysis of the brain mural cell transcriptome.
Scientific reports
He L,Vanlandewijck M,Raschperger E,Andaloussi Mäe M,Jung B,Lebouvier T,Ando K,Hofmann J,Keller A,Betsholtz C
Published figure using CD140b (PDGFRB) monoclonal antibody (Product # 14-1402-82) in Immunofluorescence
Tue Oct 11 00:00:00 EDT 2016
Endothelial cells are progenitors of cardiac pericytes and vascular smooth muscle cells.
Nature communications
Chen Q,Zhang H,Liu Y,Adams S,Eilken H,Stehling M,Corada M,Dejana E,Zhou B,Adams RH
Published figure using CD140b (PDGFRB) monoclonal antibody (Product # 14-1402-82) in Immunofluorescence
Fri Aug 12 00:00:00 EDT 2016
Endothelial cells are progenitors of cardiac pericytes and vascular smooth muscle cells.
Nature communications
Chen Q,Zhang H,Liu Y,Adams S,Eilken H,Stehling M,Corada M,Dejana E,Zhou B,Adams RH
Published figure using CD140b (PDGFRB) monoclonal antibody (Product # 14-1402-82) in Immunofluorescence
Fri Aug 12 00:00:00 EDT 2016
Overexpression of Heme Oxygenase-1 Prevents Renal Interstitial Inflammation and Fibrosis Induced by Unilateral Ureter Obstruction.
PloS one
Chen X,Wei SY,Li JS,Zhang QF,Wang YX,Zhao SL,Yu J,Wang C,Qin Y,Wei QJ,Lv GX,Li B
14140282 was used in immunohistochemistry - paraffin section to study the effect of heme oxygenase-1 on renal fibrosis using a unilateral ureter obstruction model
Fri Jul 08 00:00:00 EDT 2016
Mesodermal iPSC-derived progenitor cells functionally regenerate cardiac and skeletal muscle.
The Journal of clinical investigation
Quattrocelli M,Swinnen M,Giacomazzi G,Camps J,Barthélemy I,Ceccarelli G,Caluwé E,Grosemans H,Thorrez L,Pelizzo G,Muijtjens M,Verfaillie CM,Blot S,Janssens S,Sampaolesi M
Published figure using CD140b (PDGFRB) monoclonal antibody (Product # 14-1402-82) in Flow Cytometry
Tue Dec 01 00:00:00 EST 2015
The αvβ1 integrin plays a critical in vivo role in tissue fibrosis.
Science translational medicine
Reed NI,Jo H,Chen C,Tsujino K,Arnold TD,DeGrado WF,Sheppard D
Published figure using CD140b (PDGFRB) monoclonal antibody (Product # 14-1402-82) in Immunofluorescence
Wed May 20 00:00:00 EDT 2015
Regional and stage-specific effects of prospectively purified vascular cells on the adult V-SVZ neural stem cell lineage.
The Journal of neuroscience : the official journal of the Society for Neuroscience
Crouch EE,Liu C,Silva-Vargas V,Doetsch F
Published figure using CD140b (PDGFRB) monoclonal antibody (Product # 14-1402-82) in Immunofluorescence
Wed Mar 18 00:00:00 EDT 2015
Regional and stage-specific effects of prospectively purified vascular cells on the adult V-SVZ neural stem cell lineage.
The Journal of neuroscience : the official journal of the Society for Neuroscience
Crouch EE,Liu C,Silva-Vargas V,Doetsch F
Published figure using CD140b (PDGFRB) monoclonal antibody (Product # 14-1402-82) in Immunofluorescence
Wed Mar 18 00:00:00 EDT 2015
Regional and stage-specific effects of prospectively purified vascular cells on the adult V-SVZ neural stem cell lineage.
The Journal of neuroscience : the official journal of the Society for Neuroscience
Crouch EE,Liu C,Silva-Vargas V,Doetsch F
Published figure using CD140b (PDGFRB) monoclonal antibody (Product # 14-1402-82) in Immunofluorescence
Wed Mar 18 00:00:00 EDT 2015
Fibroblast Growth Factor 9 Imparts Hierarchy and Vasoreactivity to the Microcirculation of Renal Tumors and Suppresses Metastases.
The Journal of biological chemistry
Yin H,Frontini MJ,Arpino JM,Nong Z,O'Neil C,Xu Y,Balint B,Ward AD,Chakrabarti S,Ellis CG,Gros R,Pickering JG
Published figure using CD140b (PDGFRB) monoclonal antibody (Product # 14-1402-82) in Immunofluorescence
Fri Sep 04 00:00:00 EDT 2015
Fibroblast Growth Factor 9 Imparts Hierarchy and Vasoreactivity to the Microcirculation of Renal Tumors and Suppresses Metastases.
The Journal of biological chemistry
Yin H,Frontini MJ,Arpino JM,Nong Z,O'Neil C,Xu Y,Balint B,Ward AD,Chakrabarti S,Ellis CG,Gros R,Pickering JG
Published figure using CD140b (PDGFRB) monoclonal antibody (Product # 14-1402-82) in Immunofluorescence
Fri Sep 04 00:00:00 EDT 2015
Fibroblast Growth Factor 9 Imparts Hierarchy and Vasoreactivity to the Microcirculation of Renal Tumors and Suppresses Metastases.
The Journal of biological chemistry
Yin H,Frontini MJ,Arpino JM,Nong Z,O'Neil C,Xu Y,Balint B,Ward AD,Chakrabarti S,Ellis CG,Gros R,Pickering JG
Published figure using CD140b (PDGFRB) monoclonal antibody (Product # 14-1402-82) in Immunofluorescence
Fri Sep 04 00:00:00 EDT 2015
Fibroblast Growth Factor 9 Imparts Hierarchy and Vasoreactivity to the Microcirculation of Renal Tumors and Suppresses Metastases.
The Journal of biological chemistry
Yin H,Frontini MJ,Arpino JM,Nong Z,O'Neil C,Xu Y,Balint B,Ward AD,Chakrabarti S,Ellis CG,Gros R,Pickering JG
Published figure using CD140b (PDGFRB) monoclonal antibody (Product # 14-1402-82) in Immunofluorescence
Fri Sep 04 00:00:00 EDT 2015
Pericytes are progenitors for coronary artery smooth muscle.
eLife
Volz KS,Jacobs AH,Chen HI,Poduri A,McKay AS,Riordan DP,Kofler N,Kitajewski J,Weissman I,Red-Horse K
14-1402 was used in Immunohistochemistry to demonstrate that pericytes are progenitors for smooth muscle, and their presence in adult hearts is a new potential cell type for targeting during cardiovascular disease.
Mon Oct 19 00:00:00 EDT 2015
Renal stromal miRNAs are required for normal nephrogenesis and glomerular mesangial survival.
Physiological reports
Phua YL,Chu JY,Marrone AK,Bodnar AJ,Sims-Lucas S,Ho J
14-1402 was used in Immunofluorescence to support the indispensable role for stromal miRNAs in the regulation of apoptosis during kidney development.
Thu Oct 01 00:00:00 EDT 2015
Mfsd2a is critical for the formation and function of the blood-brain barrier.
Nature
Ben-Zvi A,Lacoste B,Kur E,Andreone BJ,Mayshar Y,Yan H,Gu C
Published figure using CD140b (PDGFRB) monoclonal antibody (Product # 14-1402-82) in Immunofluorescence
Thu May 22 00:00:00 EDT 2014
Secretion of shh by a neurovascular bundle niche supports mesenchymal stem cell homeostasis in the adult mouse incisor.
Cell stem cell
Zhao H,Feng J,Seidel K,Shi S,Klein O,Sharpe P,Chai Y
14-1402 was used in Immunofluorescence to demonstrate that mesenchymal stem cells originate from periarterial cells and are regulated by Shh secretion from a neurovascular bundle.
Thu Feb 06 00:00:00 EST 2014
Cell-specific translational profiling in acute kidney injury.
The Journal of clinical investigation
Liu J,Krautzberger AM,Sui SH,Hofmann OM,Chen Y,Baetscher M,Grgic I,Kumar S,Humphreys BD,Hide WA,McMahon AP
14-1402 was used in Immunofluorescence on frozen tissues to provide a deep, cell-based view of early injury-associated molecular events in acute kidney injury.
Sat Mar 01 00:00:00 EST 2014
Lymphatic regulator PROX1 determines Schlemm's canal integrity and identity.
The Journal of clinical investigation
Park DY,Lee J,Park I,Choi D,Lee S,Song S,Hwang Y,Hong KY,Nakaoka Y,Makinen T,Kim P,Alitalo K,Hong YK,Koh GY
14-1402 was used in Immunohistochemistry to indicate that PROX1 is an accurate and reliable biosensor of schlemm''s canal (SC) integrity and identity.
Mon Sep 01 00:00:00 EDT 2014
The myeloid-binding peptide adenoviral vector enables multi-organ vascular endothelial gene targeting.
Laboratory investigation; a journal of technical methods and pathology
Lu ZH,Kaliberov S,Zhang J,Muz B,Azab AK,Sohn RE,Kaliberova L,Du Y,Curiel DT,Arbeit JM
14-1402 was used in Immunofluorescence on frozen tissues to investigate the use of the myeloid-binding peptide in gene therapy.
Fri Aug 01 00:00:00 EDT 2014
Formation of persistent hyperplastic primary vitreous in ephrin-A5-/- mice.
Investigative ophthalmology & visual science
Son AI,Sheleg M,Cooper MA,Sun Y,Kleiman NJ,Zhou R
Published figure using CD140b (PDGFRB) monoclonal antibody (Product # 14-1402-82) in Immunofluorescence
Wed Mar 19 00:00:00 EDT 2014
Distribution of microsomal prostaglandin E synthase-1 in the mouse brain.
The Journal of comparative neurology
Eskilsson A,Tachikawa M,Hosoya K,Blomqvist A
Published figure using CD140b (PDGFRB) monoclonal antibody (Product # 14-1402-82) in Immunofluorescence
Wed Oct 01 00:00:00 EDT 2014
Astrocytic laminin regulates pericyte differentiation and maintains blood brain barrier integrity.
Nature communications
Yao Y,Chen ZL,Norris EH,Strickland S
Published figure using CD140b (PDGFRB) monoclonal antibody (Product # 14-1402-82) in Immunofluorescence
Mon Mar 03 00:00:00 EST 2014
The Wilms' tumour suppressor Wt1 is a major regulator of tumour angiogenesis and progression.
Nature communications
Wagner KD,Cherfils-Vicini J,Hosen N,Hohenstein P,Gilson E,Hastie ND,Michiels JF,Wagner N
14-1402 was used in Flow cytometry/Cell sorting to show that inducible knockout of Wt1 is sufficient to cause regression of tumour vascularisation and enhanced anti-tumour immune responses in mice.
Tue Dec 16 00:00:00 EST 2014
Imatinib disrupts lymphoma angiogenesis by targeting vascular pericytes.
Blood
Ruan J,Luo M,Wang C,Fan L,Yang SN,Cardenas M,Geng H,Leonard JP,Melnick A,Cerchietti L,Hajjar KA
14-1402 was used in Immunohistochemistry on frozen tissues to indicate that platelet-derived growth factor receptor Β pericytes may represent a novel, nonendothelial, antiangiogenic target for lymphoma therapy.
Thu Jun 27 00:00:00 EDT 2013
Wnt4/β-catenin signaling in medullary kidney myofibroblasts.
Journal of the American Society of Nephrology : JASN
DiRocco DP,Kobayashi A,Taketo MM,McMahon AP,Humphreys BD
Published figure using CD140b (PDGFRB) monoclonal antibody (Product # 14-1402-82) in Immunofluorescence
Sun Sep 01 00:00:00 EDT 2013
Ephrin-B2 controls PDGFRβ internalization and signaling.
Genes & development
Nakayama A,Nakayama M,Turner CJ,Höing S,Lepore JJ,Adams RH
Published figure using CD140b (PDGFRB) monoclonal antibody (Product # 14-1402-82) in Immunofluorescence
Sun Dec 01 00:00:00 EST 2013
Ephrin-B2 controls PDGFRβ internalization and signaling.
Genes & development
Nakayama A,Nakayama M,Turner CJ,Höing S,Lepore JJ,Adams RH
Published figure using CD140b (PDGFRB) monoclonal antibody (Product # 14-1402-82) in Immunofluorescence
Sun Dec 01 00:00:00 EST 2013
Ephrin-B2 controls PDGFRβ internalization and signaling.
Genes & development
Nakayama A,Nakayama M,Turner CJ,Höing S,Lepore JJ,Adams RH
Published figure using CD140b (PDGFRB) monoclonal antibody (Product # 14-1402-82) in Immunofluorescence
Sun Dec 01 00:00:00 EST 2013
Role of vascular endothelial growth factor in maintenance of pregnancy in mice.
Endocrinology
Wada Y,Ozaki H,Abe N,Mori A,Sakamoto K,Nagamitsu T,Nakahara T,Ishii K
14-1402 was used in Immunohistochemistry to suggest that the vascular endothelial growth factor system in the corpus luteum plays a critical role in maintaining a high level of circulating progesterone.
Fri Feb 01 00:00:00 EST 2013
High glucose and diabetes modulate cellular proteasome function: Implications in the pathogenesis of diabetes complications.
Biochemical and biophysical research communications
Aghdam SY,Gurel Z,Ghaffarieh A,Sorenson CM,Sheibani N
Published figure using CD140b (PDGFRB) monoclonal antibody (Product # 14-1402-82) in Immunofluorescence
Fri Mar 08 00:00:00 EST 2013
Pericytes derived from adipose-derived stem cells protect against retinal vasculopathy.
PloS one
Mendel TA,Clabough EB,Kao DS,Demidova-Rice TN,Durham JT,Zotter BC,Seaman SA,Cronk SM,Rakoczy EP,Katz AJ,Herman IM,Peirce SM,Yates PA
Published figure using CD140b (PDGFRB) monoclonal antibody (Product # 14-1402-82) in Flow Cytometry
Fri Jan 10 00:00:00 EST 2014
Regulator of G-protein signaling 5 (RGS5) protein: a novel marker of cancer vasculature elicited and sustained by the tumor's proangiogenic microenvironment.
Cellular and molecular life sciences : CMLS
Silini A,Ghilardi C,Figini S,Sangalli F,Fruscio R,Dahse R,Pedley RB,Giavazzi R,Bani M
14-1402 was used in Immunocytochemistry-immunoflourescence to provide the first in vivo/ex vivo evidence of regulator of G-protein signalling 5 protein in the vasculature of ovarian carcinoma clinical specimens and its absence in human ovaries.
Sun Apr 01 00:00:00 EDT 2012
Regulator of G-protein signaling 5 (RGS5) protein: a novel marker of cancer vasculature elicited and sustained by the tumor's proangiogenic microenvironment.
Cellular and molecular life sciences : CMLS
Silini A,Ghilardi C,Figini S,Sangalli F,Fruscio R,Dahse R,Pedley RB,Giavazzi R,Bani M
14-1402 was used in Immunocytochemistry-immunoflourescence to provide the first in vivo/ex vivo evidence of regulator of G-protein signalling 5 protein in the vasculature of ovarian carcinoma clinical specimens and its absence in human ovaries.
Sun Apr 01 00:00:00 EDT 2012
The bHLH transcription factor Tcf21 is required for lineage-specific EMT of cardiac fibroblast progenitors.
Development (Cambridge, England)
Acharya A,Baek ST,Huang G,Eskiocak B,Goetsch S,Sung CY,Banfi S,Sauer MF,Olsen GS,Duffield JS,Olson EN,Tallquist MD
Published figure using CD140b (PDGFRB) monoclonal antibody (Product # 14-1402-82) in Immunofluorescence
Fri Jun 01 00:00:00 EDT 2012
Hedgehog-Gli pathway activation during kidney fibrosis.
The American journal of pathology
Fabian SL,Penchev RR,St-Jacques B,Rao AN,Sipilä P,West KA,McMahon AP,Humphreys BD
14-1402 was used in Immunohistochemistry to describe paracrine hedgehog signaling in adult kidney, which indicates a possible role for hedgehog-Gli signaling in fibrotic chronic kidney disease.
Sun Apr 01 00:00:00 EDT 2012
INK4a deletion results in improved kidney regeneration and decreased capillary rarefaction after ischemia-reperfusion injury.
American journal of physiology. Renal physiology
Lee DH,Wolstein JM,Pudasaini B,Plotkin M
14-1402 was used in Immunohistochemistry to investigate the molecular mechanisms that lead to tubular atrophy, capillary loss, and fibrosis following acute kidney injury.
Sun Jan 01 00:00:00 EST 2012
Penetration and differentiation of cephalic neural crest-derived cells in the developing mouse telencephalon.
Development, growth & differentiation
Yamanishi E,Takahashi M,Saga Y,Osumi N
14-1402 was used in Immunohistochemistry to study when and how cephalic neural crest-derived cells invade the telencephalon and differentiate into pericytes.
Sat Dec 01 00:00:00 EST 2012
Necdin controls proliferation of white adipocyte progenitor cells.
PloS one
Fujiwara K,Hasegawa K,Ohkumo T,Miyoshi H,Tseng YH,Yoshikawa K
14-1402 was used in Immunocytochemistry to investigate the molecular mechanisms that regulate preadipocyte proliferation during adipose tissue development, showing that proliferation is controlled by Necdin.
Mon Jun 04 00:00:00 EDT 2012
The tyrphostin agent AG490 prevents and reverses type 1 diabetes in NOD mice.
PloS one
Davoodi-Semiromi A,Wasserfall CH,Xia CQ,Cooper-DeHoff RM,Wabitsch M,Clare-Salzler M,Atkinson M
14-1402 was used in Western Blotting to analyse the development and/or reversal of diabetes, insulitis, adoptive transfer, and other mechanistic studies using NOD mice.
Fri Sep 14 00:00:00 EDT 2012
Characterization and fate of telomerase-expressing epithelia during kidney repair.
Journal of the American Society of Nephrology : JASN
Song J,Czerniak S,Wang T,Ying W,Carlone DL,Breault DT,Humphreys BD
14-1402 was used in Immunofluorescence to elucidate the role of telomere length for kidney repair.
Thu Dec 01 00:00:00 EST 2011
Multiple stromal populations contribute to pulmonary fibrosis without evidence for epithelial to mesenchymal transition.
Proceedings of the National Academy of Sciences of the United States of America
Rock JR,Barkauskas CE,Cronce MJ,Xue Y,Harris JR,Liang J,Noble PW,Hogan BL
Published figure using CD140b (PDGFRB) monoclonal antibody (Product # 14-1402-82) in Immunofluorescence
Tue Dec 27 00:00:00 EST 2011
Pericyte requirement for anti-leak action of angiopoietin-1 and vascular remodeling in sustained inflammation.
The American journal of pathology
Fuxe J,Tabruyn S,Colton K,Zaid H,Adams A,Baluk P,Lashnits E,Morisada T,Le T,O'Brien S,Epstein DM,Koh GY,McDonald DM
14-1402 was used in Immunohistochemistry to show that pericyte contributions to endothelial stability have greater dependence on PDGF-B during the development of sustained inflammation than under baseline conditions or in acute inflammation.
Wed Jun 01 00:00:00 EDT 2011
Activation of PDGFr-β Signaling Pathway after Imatinib and Radioimmunotherapy Treatment in Experimental Pancreatic Cancer.
Cancers
Abe M,Kortylewicz ZP,Enke CA,Mack E,Baranowska-Kortylewicz J
14-1402 was used in an ELISA assay to examine the PDGFr-β/PDGF-B pathways in both human and murine models of tumours.
Wed May 25 00:00:00 EDT 2011
Activation of PDGFr-β Signaling Pathway after Imatinib and Radioimmunotherapy Treatment in Experimental Pancreatic Cancer.
Cancers
Abe M,Kortylewicz ZP,Enke CA,Mack E,Baranowska-Kortylewicz J
14-1402 was used in an ELISA assay to examine the PDGFr-β/PDGF-B pathways in both human and murine models of tumours.
Wed May 25 00:00:00 EDT 2011
Differential contribution to neuroendocrine tumorigenesis of parallel egfr signaling in cancer cells and pericytes.
Genes & cancer
Nolan-Stevaux O,Truitt MC,Pahler JC,Olson P,Guinto C,Lee DC,Hanahan D
14-1402 was used in Immunohistochemistry-immunofluorescence to associate Tgf-α and Hb-egf expression with wild-type Egfr oncogenicity and ascribes the proangiogenic activity of Egfr to a mesenchymal Hb-egf/Egfr signalling axis.
Mon Feb 01 00:00:00 EST 2010
Differential contribution to neuroendocrine tumorigenesis of parallel egfr signaling in cancer cells and pericytes.
Genes & cancer
Nolan-Stevaux O,Truitt MC,Pahler JC,Olson P,Guinto C,Lee DC,Hanahan D
14-1402 was used in Immunohistochemistry-immunofluorescence to associate Tgf-α and Hb-egf expression with wild-type Egfr oncogenicity and ascribes the proangiogenic activity of Egfr to a mesenchymal Hb-egf/Egfr signalling axis.
Mon Feb 01 00:00:00 EST 2010
Contrasting actions of selective inhibitors of angiopoietin-1 and angiopoietin-2 on the normalization of tumor blood vessels.
The American journal of pathology
Falcón BL,Hashizume H,Koumoutsakos P,Chou J,Bready JV,Coxon A,Oliner JD,McDonald DM
14-1402 was used in Immunohistochemistry to study how inhibition of Ang2 leads to normalization of tumor blood vessels by permitting the unopposed action of Ang1, but decreases tumor vascularity primarily by blocking Ang2 actions.
Sun Nov 01 00:00:00 EDT 2009
Localization of mesenchymal cells in adult mouse thymus: their abnormal distribution in mice with disorganization of thymic medullary epithelium.
The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society
Odaka C
14-1402 was used in Immunohistochemistry to examine the expression of mesenchymal markers in the thymi of normal adult mice.
Wed Apr 01 00:00:00 EDT 2009
Six2 defines and regulates a multipotent self-renewing nephron progenitor population throughout mammalian kidney development.
Cell stem cell
Kobayashi A,Valerius MT,Mugford JW,Carroll TJ,Self M,Oliver G,McMahon AP
Thu Aug 07 00:00:00 EDT 2008
Mesothelium contributes to vascular smooth muscle and mesenchyme during lung development.
Proceedings of the National Academy of Sciences of the United States of America
Que J,Wilm B,Hasegawa H,Wang F,Bader D,Hogan BL
14-1402 was used in Immunohistochemistry to show that mesothelial cells serve as a source of vascular smooth muscle cells in the developing lung.
Tue Oct 28 00:00:00 EDT 2008
LKB1 in endothelial cells is required for angiogenesis and TGFbeta-mediated vascular smooth muscle cell recruitment.
Development (Cambridge, England)
Londesborough A,Vaahtomeri K,Tiainen M,Katajisto P,Ekman N,Vallenius T,Mäkelä TP
14-1402 was used in Immunohistochemistry-immunofluorescence to investigate the defects underlying the Lkb1(-/-) phenotype.
Tue Jul 01 00:00:00 EDT 2008
Defective N-sulfation of heparan sulfate proteoglycans limits PDGF-BB binding and pericyte recruitment in vascular development.
Genes & development
Abramsson A,Kurup S,Busse M,Yamada S,Lindblom P,Schallmeiner E,Stenzel D,Sauvaget D,Ledin J,Ringvall M,Landegren U,Kjellén L,Bondjers G,Li JP,Lindahl U,Spillmann D,Betsholtz C,Gerhardt H
14-1402 was used in Immunohistochemistry to study the participation of heparan sulfate chains in pericyte recruitment using two mouse models with altered heparan sulfate biosynthesis.
Thu Feb 01 00:00:00 EST 2007
The role of platelet-derived growth factor signaling in healing myocardial infarcts.
Journal of the American College of Cardiology
Zymek P,Bujak M,Chatila K,Cieslak A,Thakker G,Entman ML,Frangogiannis NG
14-1402 was used in Immunohistochemistry to show that PDGFR-beta- and PDGFR-alpha-mediated pathways promote collagen deposition in the infarct and recruit mural cells promoting resolution of inflammation.
Tue Dec 05 00:00:00 EST 2006
Vascular endothelial growth factor a signaling in the podocyte-endothelial compartment is required for mesangial cell migration and survival.
Journal of the American Society of Nephrology : JASN
Eremina V,Cui S,Gerber H,Ferrara N,Haigh J,Nagy A,Ema M,Rossant J,Jothy S,Miner JH,Quaggin SE
14-1402 was used in Immunohistochemistry-immunofluorescence to study the role of VEGF-A signalling for mesangial cell survival and differentiation.
Wed Mar 01 00:00:00 EST 2006
Inhibition of platelet-derived growth factor B signaling enhances the efficacy of anti-vascular endothelial growth factor therapy in multiple models of ocular neovascularization.
The American journal of pathology
Jo N,Mailhos C,Ju M,Cheung E,Bradley J,Nishijima K,Robinson GS,Adamis AP,Shima DT
14-1402 was used in Immunohistochemistry to investigate blood vessel growth factor dependency, and validate a combination therapy strategy for enhancing the current treatments for ocular angiogenic disease.
Thu Jun 01 00:00:00 EDT 2006
VEGF-A and FGF-2 synergistically promote neoangiogenesis through enhancement of endogenous PDGF-B-PDGFRbeta signaling.
Journal of cell science
Kano MR,Morishita Y,Iwata C,Iwasaka S,Watabe T,Ouchi Y,Miyazono K,Miyazawa K
14-1402 was used in Immunohistochemistry to demonstrate that enhancement of endogenous PDGF-B-PDGFR signaling is critical for the synergistic effect of VEGF-A and FGF-2 on neoangiogenesis in adults.
Mon Aug 15 00:00:00 EDT 2005
PDGFR alpha expression during mouse embryogenesis: immunolocalization analyzed by whole-mount immunohistostaining using the monoclonal anti-mouse PDGFR alpha antibody APA5.
The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society
Takakura N,Yoshida H,Ogura Y,Kataoka H,Nishikawa S,Nishikawa S
Sun Jun 01 00:00:00 EDT 1997
