Product References
Rad52 mediates class-switch DNA recombination to IgD.
Nature communications
Xu Y,Zhou H,Post G,Zan H,Casali P
Published figure using IgM monoclonal antibody (Product # 14-5790-82) in Immunohistochemistry
Mon Feb 21 00:00:00 EST 2022
Nanobodies from camelid mice and llamas neutralize SARS-CoV-2 variants.
Nature
Xu J,Xu K,Jung S,Conte A,Lieberman J,Muecksch F,Lorenzi JCC,Park S,Schmidt F,Wang Z,Huang Y,Luo Y,Nair MS,Wang P,Schulz JE,Tessarollo L,Bylund T,Chuang GY,Olia AS,Stephens T,Teng IT,Tsybovsky Y,Zhou T,Munster V,Ho DD,Hatziioannou T,Bieniasz PD,Nussenzweig MC,Kwong PD,Casellas R
Published figure using IgM monoclonal antibody (Product # 14-5790-82) in Flow Cytometry
Thu Jul 01 00:00:00 EDT 2021
Smc3 dosage regulates B cell transit through germinal centers and restricts their malignant transformation.
Nature immunology
Rivas MA,Meydan C,Chin CR,Challman MF,Kim D,Bhinder B,Kloetgen A,Viny AD,Teater MR,McNally DR,Doane AS,Béguelin W,Fernández MTC,Shen H,Wang X,Levine RL,Chen Z,Tsirigos A,Elemento O,Mason CE,Melnick AM
Published figure using IgM monoclonal antibody (Product # 14-5790-82) in Flow Cytometry
Mon Feb 01 00:00:00 EST 2021
A platform-agnostic, function first-based antibody discovery strategy using plasmid-free mammalian expression of antibodies.
mAbs
Zhang R,Prabakaran P,Yu X,Mackness BC,Boudanova E,Hopke J,Sancho J,Saleh J,Cho H,Zhang N,Simonds-Mannes H,Stimple SD,Hoffmann D,Park A,Chowdhury PS,Rao SP
Published figure using IgM monoclonal antibody (Product # 14-5790-82) in Flow Cytometry
Wed Jan 19 00:00:00 EST 2022
Stearoyl-CoA Desaturase-Mediated Monounsaturated Fatty Acid Availability Supports Humoral Immunity.
Cell reports
Zhou X,Zhu X,Li C,Li Y,Ye Z,Shapiro VS,Copland JA,Hitosugi T,Bernlohr DA,Sun J,Zeng H
Published figure using IgM monoclonal antibody (Product # 14-5790-82) in ELISA
Tue Jan 05 00:00:00 EST 2021
A booster dose enhances immunogenicity of the COVID-19 vaccine candidate ChAdOx1 nCoV-19 in aged mice.
Med (New York, N.Y.)
Silva-Cayetano A,Foster WS,Innocentin S,Belij-Rammerstorfer S,Spencer AJ,Burton OT,Fra-Bidó S,Le Lee J,Thakur N,Conceicao C,Wright D,Barrett J,Evans-Bailey N,Noble C,Bailey D,Liston A,Gilbert SC,Lambe T,Linterman MA
14-5790-82 was used in Flow Cytometry to show that ChAdOx1 nCoV-19 induces both cellular and humoral immunity in adult and aged mice and suggest a prime-boost strategy is a rational approach to enhance immunogenicity in older persons.
Fri Mar 12 00:00:00 EST 2021
Construction, characterization, and immunization of nanoparticles that display a diverse array of influenza HA trimers.
PloS one
Cohen AA,Yang Z,Gnanapragasam PNP,Ou S,Dam KA,Wang H,Bjorkman PJ
Published figure using IgM monoclonal antibody (Product # 14-5790-82) in Flow Cytometry
Fri Oct 15 00:00:00 EDT 2021
Therapeutic Targeting of Vasculature in the Premetastatic and Metastatic Niches Reduces Lung Metastasis.
Journal of immunology (Baltimore, Md. : 1950)
Ghouse SM,Vadrevu SK,Manne S,Reese B,Patel J,Patel B,Silwal A,Lodhi N,Paterson Y,Srivastava SK,Karbowniczek M,Markiewski MM
14-5790-85 was used in Immunohistochemistry (Frozen) to provide initial evidence that angiogenesis contributes to the premetastatic niche in rapidly progressing cancers and that inhibiting this process through immunotherapy is beneficial for reducing or even preventing metastasis.
Sat Feb 15 00:00:00 EST 2020
B Cell Diversification Is Uncoupled from SAP-Mediated Selection Forces in Chronic Germinal Centers within Peyer's Patches.
Cell reports
Biram A,Winter E,Denton AE,Zaretsky I,Dassa B,Bemark M,Linterman MA,Yaari G,Shulman Z
Published figure using IgM monoclonal antibody (Product # 14-5790-82) in Flow Cytometry
Tue Feb 11 00:00:00 EST 2020
Chronic Viral Infection Promotes Efficient Germinal Center B Cell Responses.
Cell reports
Fallet B,Hao Y,Florova M,Cornille K,de Los Aires AV,Girelli Zubani G,Ertuna YI,Greiff V,Menzel U,Hammad K,Merkler D,Reddy ST,Weill JC,Reynaud CA,Pinschewer DD
Published figure using IgM monoclonal antibody (Product # 14-5790-82) in Flow Cytometry
Tue Jan 28 00:00:00 EST 2020
Decreased immunoglobulin G in brain regions of elder female APOE4-TR mice accompany with Aβ accumulation.
Immunity & ageing : I & A
Zhang L,Xu J,Gao J,Chen P,Yin M,Zhao W
14-5790-82 was used in Flow Cytometry to determine the alterations of IgG, CD19, and Aβ in various brain regions of uninfected male and female APOE3- and APOE4-TR mice at the age of 3 and 10 months to elucidate impacts of AD risk factors on alterations of brain IgG.
Thu Mar 31 00:00:00 EDT 2022
TET enzymes control antibody production and shape the mutational landscape in germinal centre B cells.
The FEBS journal
Schoeler K,Aufschnaiter A,Messner S,Derudder E,Herzog S,Villunger A,Rajewsky K,Labi V
Published figure using IgM monoclonal antibody (Product # 14-5790-82) in Flow Cytometry
Sun Sep 01 00:00:00 EDT 2019
Distinct Requirements of CHD4 during B Cell Development and Antibody Response.
Cell reports
Yen WF,Sharma R,Cols M,Lau CM,Chaudhry A,Chowdhury P,Yewdell WT,Vaidyanathan B,Sun A,Coffre M,Pucella JN,Chen CC,Jasin M,Sun JC,Rudensky AY,Koralov SB,Chaudhuri J
Published figure using IgM monoclonal antibody (Product # 14-5790-82) in ELISA
Tue Apr 30 00:00:00 EDT 2019
Inducible IL-7 Hyperexpression Influences Lymphocyte Homeostasis and Function and Increases Allograft Rejection.
Frontiers in immunology
Schreiber M,Weigelt M,Karasinsky A,Anastassiadis K,Schallenberg S,Petzold C,Bonifacio E,Kretschmer K,Hommel A
14-5790 was used in Flow cytometry/Cell sorting to show that transient hyperexpression of IL-7 can impair immune regulation, through disturbances in lymphocyte development pathways, and decrease graft survival time, even under immunosuppression.
Mon Sep 14 00:00:00 EDT 2020
Anti‑IL‑39 (IL‑23p19/Ebi3) polyclonal antibodies ameliorate autoimmune symptoms in lupus‑like mice.
Molecular medicine reports
Wang X,Zhang Y,Wang Z,Liu X,Zhu G,Han G,Chen G,Hou C,Wang T,Shen B,Li Y,Xiao H,Ma N,Wang R
Published figure using IgM monoclonal antibody (Product # 14-5790-82) in ELISA
Mon Jan 01 00:00:00 EST 2018
A protocol for generating induced T cells by reprogramming B cells in vivo.
Cell regeneration (London, England)
Weng Q,Hu F,Zhang M,Dong Y,Lv C,Wang Y,Liu X,Wang J
Published figure using IgM monoclonal antibody (Product # 14-5790-82) in Flow Cytometry
Sat Sep 01 00:00:00 EDT 2018
PI3Kδ hyper-activation promotes development of B cells that exacerbate Streptococcus pneumoniae infection in an antibody-independent manner.
Nature communications
Stark AK,Chandra A,Chakraborty K,Alam R,Carbonaro V,Clark J,Sriskantharajah S,Bradley G,Richter AG,Banham-Hall E,Clatworthy MR,Nejentsev S,Hamblin JN,Hessel EM,Condliffe AM,Okkenhaug K
Published figure using IgM monoclonal antibody (Product # 14-5790-82) in T-Cell Activation
Thu Aug 09 00:00:00 EDT 2018
High-affinity IgM+ memory B cells are defective in differentiation into IgM antibody-secreting cells by re-stimulation with a T cell-dependent antigen.
Scientific reports
Tashiro Y,Murakami A,Hara Y,Shimizu T,Kubo M,Goitsuka R,Kishimoto H,Azuma T
14-5790 was used in Flow cytometry/Cell sorting to demonstrate that only non-germinal centre-dependent IgM+ memomry B cells have terminal differential potential to become plasma cell during recall immune response.
Fri Sep 28 00:00:00 EDT 2018
The microanatomic segregation of selection by apoptosis in the germinal center.
Science (New York, N.Y.)
Mayer CT,Gazumyan A,Kara EE,Gitlin AD,Golijanin J,Viant C,Pai J,Oliveira TY,Wang Q,Escolano A,Medina-Ramirez M,Sanders RW,Nussenzweig MC
14-5790 was used in Flow cytometry/Cell sorting to visualise, purify and characterise dying germinal centres B cells in apoptosis-indicator mice.
Fri Oct 13 00:00:00 EDT 2017
Functional characterization of the lysosomal membrane protein TMEM192 in mice.
Oncotarget
Nguyen TL,Schneppenheim J,Rudnik S,Lüllmann-Rauch R,Bernreuther C,Hermans-Borgmeyer I,Glatzel M,Saftig P,Schröder B
14-5790-82 was used in Flow Cytometry to conclude that under basal conditions in vivo the loss of TMEM192 can be efficiently compensated by alternative pathways.
Tue Jul 04 00:00:00 EDT 2017
Early derivation of IgM memory cells and bone marrow plasmablasts.
PloS one
Papillion AM,Kenderes KJ,Yates JL,Winslow GM
14-5790 was used in Flow cytometry/Cell sorting to demonstrate that two distinct long-term IgM-positive B cell populations are generated early in response to infection but maintained bu separate mechanisms.
Fri Sep 22 00:00:00 EDT 2017
Conversion of T cells to B cells by inactivation of polycomb-mediated epigenetic suppression of the B-lineage program.
Genes & development
Ikawa T,Masuda K,Endo TA,Endo M,Isono K,Koseki Y,Nakagawa R,Kometani K,Takano J,Agata Y,Katsura Y,Kurosaki T,Vidal M,Koseki H,Kawamoto H
Published figure using IgM monoclonal antibody (Product # 14-5790-82) in ELISA
Tue Nov 15 00:00:00 EST 2016
Conversion of T cells to B cells by inactivation of polycomb-mediated epigenetic suppression of the B-lineage program.
Genes & development
Ikawa T,Masuda K,Endo TA,Endo M,Isono K,Koseki Y,Nakagawa R,Kometani K,Takano J,Agata Y,Katsura Y,Kurosaki T,Vidal M,Koseki H,Kawamoto H
Published figure using IgM monoclonal antibody (Product # 14-5790-82) in ELISA
Tue Nov 15 00:00:00 EST 2016
Ligase I and ligase III mediate the DNA double-strand break ligation in alternative end-joining.
Proceedings of the National Academy of Sciences of the United States of America
Lu G,Duan J,Shu S,Wang X,Gao L,Guo J,Zhang Y
Published figure using IgM monoclonal antibody (Product # 14-5790-82) in Flow Cytometry
Tue Feb 02 00:00:00 EST 2016
Protective Role for B-1b B Cells and IgM in Obesity-Associated Inflammation, Glucose Intolerance, and Insulin Resistance.
Arteriosclerosis, thrombosis, and vascular biology
Harmon DB,Srikakulapu P,Kaplan JL,Oldham SN,McSkimming C,Garmey JC,Perry HM,Kirby JL,Prohaska TA,Gonen A,Hallowell P,Schirmer B,Tsimikas S,Taylor AM,Witztum JL,McNamara CA
14-5790 was used in Flow cytometry/Cell sorting to investigate the role of B-cell functions in obesity-induced metabolic dysfunction.
Fri Apr 01 00:00:00 EDT 2016
Editing of mouse and human immunoglobulin genes by CRISPR-Cas9 system.
Nature communications
Cheong TC,Compagno M,Chiarle R
Published figure using IgM monoclonal antibody (Product # 14-5790-82) in Flow Cytometry
Wed Mar 09 00:00:00 EST 2016
B cell autophagy mediates TLR7-dependent autoimmunity and inflammation.
Autophagy
Weindel CG,Richey LJ,Bolland S,Mehta AJ,Kearney JF,Huber BT
Published figure using IgM monoclonal antibody (Product # 14-5790-82) in ELISA
Mon Apr 18 00:00:00 EDT 2016
B cell autophagy mediates TLR7-dependent autoimmunity and inflammation.
Autophagy
Weindel CG,Richey LJ,Bolland S,Mehta AJ,Kearney JF,Huber BT
Published figure using IgM monoclonal antibody (Product # 14-5790-82) in ELISA
Mon Apr 18 00:00:00 EDT 2016
B cell autophagy mediates TLR7-dependent autoimmunity and inflammation.
Autophagy
Weindel CG,Richey LJ,Bolland S,Mehta AJ,Kearney JF,Huber BT
Published figure using IgM monoclonal antibody (Product # 14-5790-82) in ELISA
Mon Apr 18 00:00:00 EDT 2016
Comparison of predicted and actual consequences of missense mutations.
Proceedings of the National Academy of Sciences of the United States of America
Miosge LA,Field MA,Sontani Y,Cho V,Johnson S,Palkova A,Balakishnan B,Liang R,Zhang Y,Lyon S,Beutler B,Whittle B,Bertram EM,Enders A,Goodnow CC,Andrews TD
14-5790 was used in Flow cytometry/Cell sorting to analyse the efficacy of computational inferences of the functional significance of missense mutations in mice.
Tue Sep 15 00:00:00 EDT 2015
Mitochondrial ATP transporter Ant2 depletion impairs erythropoiesis and B lymphopoiesis.
Cell death and differentiation
Cho J,Seo J,Lim CH,Yang L,Shiratsuchi T,Lee MH,Chowdhury RR,Kasahara H,Kim JS,Oh SP,Lee YJ,Terada N
Published figure using IgM monoclonal antibody (Product # 14-5790-82) in Flow Cytometry
Tue Sep 01 00:00:00 EDT 2015
LKB1 inhibition of NF-κB in B cells prevents T follicular helper cell differentiation and germinal center formation.
EMBO reports
Walsh NC,Waters LR,Fowler JA,Lin M,Cunningham CR,Brooks DG,Rehg JE,Morse HC,Teitell MA
14-5790 was used in Flow cytometry/Cell sorting to show that LKB1 expression in B cells maintains B-cell quiescence and prevents the premature formation of germinal centers.
Mon Jun 01 00:00:00 EDT 2015
Setd1a regulates progenitor B-cell-to-precursor B-cell development through histone H3 lysine 4 trimethylation and Ig heavy-chain rearrangement.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology
Tusi BK,Deng C,Salz T,Zeumer L,Li Y,So CW,Morel LM,Qiu Y,Huang S
14-5790 was used in Flow cytometry/Cell sorting to investigate if Setd1a controls specific hematopoietic lineage commitment and differentiation during development, showing that it regulates progenitor B-cell-to-precursor B-cell development.
Wed Apr 01 00:00:00 EDT 2015
Natural IgM Switches the Function of Lipopolysaccharide-Activated Murine Bone Marrow-Derived Dendritic Cells to a Regulatory Dendritic Cell That Suppresses Innate Inflammation.
Journal of immunology (Baltimore, Md. : 1950)
Lobo PI,Schlegel KH,Bajwa A,Huang L,Kurmaeva E,Wang B,Ye H,Tedder TF,Kinsey GR,Okusa MD
14-5790 was used in Flow cytometry/Cell sorting to investigate how natural IgM anti-leukocyte Abs can switch BMDC to a regulatory phenotype despite the presence of LPS that ordinarily induces BMDC maturation.
Tue Dec 01 00:00:00 EST 2015
TNF signals are dispensable for the generation of CD23+ CD21/35-high CD1d-high B cells in inflamed lymph nodes.
Cellular immunology
Kuzin II,Bouta EM,Schwarz EM,Bottaro A
14-5790 was used in Flow cytometry/Cell sorting to investigate the role of tumor necrosis factor signals in producing and maintaining B cells in inflamed lymph nodes, and their role in rheumatoid arthritis pathogenesis.
Sat Aug 01 00:00:00 EDT 2015
Testing the role of the FcγRIIB immunoreceptor tyrosine-based inhibitory motif in regulation of the B cell immune response.
Immunity, inflammation and disease
Vuyyuru R,Shen S,Manser T
14-5790 was used in Flow cytometry/Cell sorting to test the role of the FcγRIIB ITIM motif in the regulation of B cell immune response in vivo, showing that a functional ITIM motif is not required for all inhibitory activity of this receptor, however further investigation is required to confirm this.
Tue Sep 01 00:00:00 EDT 2015
Combined MEK and JAK inhibition abrogates murine myeloproliferative neoplasm.
The Journal of clinical investigation
Kong G,Wunderlich M,Yang D,Ranheim EA,Young KH,Wang J,Chang YI,Du J,Liu Y,Tey SR,Zhang X,Juckett M,Mattison R,Damnernsawad A,Zhang J,Mulloy JC,Zhang J
14-5790 was used in Flow cytometry/Cell sorting to investigate the effect of combined targeting of MEK/ERK and JAK/STAT signalling on the murine myeloproliferative neoplasm.
Sun Jun 01 00:00:00 EDT 2014
Elucidation of the enigmatic IgD class-switch recombination via germline deletion of the IgH 3' regulatory region.
The Journal of experimental medicine
Rouaud P,Saintamand A,Saad F,Carrion C,Lecardeur S,Cogné M,Denizot Y
Published figure using IgM monoclonal antibody (Product # 14-5790-82) in Immunohistochemistry
Mon May 05 00:00:00 EDT 2014
Elucidation of the enigmatic IgD class-switch recombination via germline deletion of the IgH 3' regulatory region.
The Journal of experimental medicine
Rouaud P,Saintamand A,Saad F,Carrion C,Lecardeur S,Cogné M,Denizot Y
Published figure using IgM monoclonal antibody (Product # 14-5790-82) in Immunohistochemistry
Mon May 05 00:00:00 EDT 2014
APRIL mediates peritoneal B-1 cell homeostasis.
Immunology letters
Sindhava VJ,Scholz JL,Stohl W,Cancro MP
14-5790 was used in Flow cytometry/Cell sorting to assess the contribution of BLyS and other ligands to peritoneal B-1 cell maintenance.
Fri Aug 01 00:00:00 EDT 2014
A component of the mir-17-92 polycistronic oncomir promotes oncogene-dependent apoptosis.
eLife
Olive V,Sabio E,Bennett MJ,De Jong CS,Biton A,McGann JC,Greaney SK,Sodir NM,Zhou AY,Balakrishnan A,Foth M,Luftig MA,Goga A,Speed TP,Xuan Z,Evan GI,Wan Y,Minella AC,He L
Published figure using IgM monoclonal antibody (Product # 14-5790-82) in Flow Cytometry
Tue Oct 15 00:00:00 EDT 2013
A mouse model for inducible overexpression of Prdm14 results in rapid-onset and highly penetrant T-cell acute lymphoblastic leukemia (T-ALL).
Disease models & mechanisms
Carofino BL,Ayanga B,Justice MJ
Published figure using IgM monoclonal antibody (Product # 14-5790-82) in Flow Cytometry
Fri Nov 01 00:00:00 EDT 2013
Ebf1 and c-Myb repress rag transcription downstream of Stat5 during early B cell development.
Journal of immunology (Baltimore, Md. : 1950)
Timblin GA,Schlissel MS
14-5790 was used in Flow cytometry/Cell sorting to identify a novel pathway responsible for the transcriptional repression of Rag in developing B cells using an in vitro model system.
Fri Nov 01 00:00:00 EDT 2013
TiF1-gamma plays an essential role in murine hematopoiesis and regulates transcriptional elongation of erythroid genes.
Developmental biology
Bai X,Trowbridge JJ,Riley E,Lee JA,DiBiase A,Kaartinen VM,Orkin SH,Zon LI
14-5790 was used in Flow cytometry/Cell sorting to study the role of TIF1γ in murine erythropoiesis and to assess its function in other blood lineages.
Tue Jan 15 00:00:00 EST 2013
Differential and site specific impact of B cells in the protective immune response to Mycobacterium tuberculosis in the mouse.
PloS one
Torrado E,Fountain JJ,Robinson RT,Martino CA,Pearl JE,Rangel-Moreno J,Tighe M,Dunn R,Cooper AM
14-5790 was used in an ELISpot assay to elucidate the role of B cells for the control of mycobacterial infections.
Thu Nov 14 00:00:00 EST 2013
Differential and site specific impact of B cells in the protective immune response to Mycobacterium tuberculosis in the mouse.
PloS one
Torrado E,Fountain JJ,Robinson RT,Martino CA,Pearl JE,Rangel-Moreno J,Tighe M,Dunn R,Cooper AM
14-5790 was used in an ELISpot assay to elucidate the role of B cells for the control of mycobacterial infections.
Thu Nov 14 00:00:00 EST 2013
Human lymphoma mutations reveal CARD11 as the switch between self-antigen-induced B cell death or proliferation and autoantibody production.
The Journal of experimental medicine
Jeelall YS,Wang JQ,Law HD,Domaschenz H,Fung HK,Kallies A,Nutt SL,Goodnow CC,Horikawa K
14-5790 was used in Flow cytometry/Cell sorting to demonstrate that regulation of CARD11 signaling is a critical switch governing the decision between death and proliferation in antigen-stimulated mature B cells.
Mon Oct 22 00:00:00 EDT 2012
PIDDosome-independent tumor suppression by Caspase-2.
Cell death and differentiation
Manzl C,Peintner L,Krumschnabel G,Bock F,Labi V,Drach M,Newbold A,Johnstone R,Villunger A
14-5790 was used in Flow cytometry/Cell sorting to investigate the role of PIDD, RIP-1 kinase and Nemo/IKKγ in oncogenesis induced by DNA damage or oncogenic stress in gene-ablated mice.
Mon Oct 01 00:00:00 EDT 2012
Lung B cells promote early pathogen dissemination and hasten death from inhalation anthrax.
Mucosal immunology
Rayamajhi M,Delgado C,Condon TV,Riches DW,Lenz LL
14-5790 was used in Flow cytometry/Cell sorting to investigate mechanisms of Bacillus anthracis spore traffic from the lungs to the lung-draining lymph nodes in a mouse model of inhalation anthrax.
Sun Jul 01 00:00:00 EDT 2012
Critical role of B cell lymphoma 10 in BAFF-regulated NF-κB activation and survival of anergic B cells.
Journal of immunology (Baltimore, Md. : 1950)
Yu M,Chen Y,He Y,Podd A,Fu G,Wright JA,Kleiman E,Khan WN,Wen R,Wang D
Published figure using IgM monoclonal antibody (Product # 14-5790-82) in Flow Cytometry
Sat Dec 01 00:00:00 EST 2012
Peroxisome proliferator-activated receptor γ B cell-specific-deficient mice have an impaired antibody response.
Journal of immunology (Baltimore, Md. : 1950)
Ramon S,Bancos S,Thatcher TH,Murant TI,Moshkani S,Sahler JM,Bottaro A,Sime PJ,Phipps RP
14-5790 was used in Flow cytometry/Cell sorting to study how PPARγ expression in B cells is required for an efficient B cell-mediated immune response by regulating B cell differentiation and Ab production.
Thu Nov 15 00:00:00 EST 2012
Development and function of murine B cells lacking RANK.
Journal of immunology (Baltimore, Md. : 1950)
Perlot T,Penninger JM
14-5790 was used in Flow cytometry/Cell sorting to indicate that ablation of the RANKL-RANK pathway has no direct adverse effect on B cell physiology.
Wed Feb 01 00:00:00 EST 2012
Nuclear export of the NF-κB inhibitor IκBα is required for proper B cell and secondary lymphoid tissue formation.
Immunity
Wuerzberger-Davis SM,Chen Y,Yang DT,Kearns JD,Bates PW,Lynch C,Ladell NC,Yu M,Podd A,Zeng H,Huang TT,Wen R,Hoffmann A,Wang D,Miyamoto S
Published figure using IgM monoclonal antibody (Product # 14-5790-82) in Flow Cytometry
Fri Feb 25 00:00:00 EST 2011
Nuclear export of the NF-κB inhibitor IκBα is required for proper B cell and secondary lymphoid tissue formation.
Immunity
Wuerzberger-Davis SM,Chen Y,Yang DT,Kearns JD,Bates PW,Lynch C,Ladell NC,Yu M,Podd A,Zeng H,Huang TT,Wen R,Hoffmann A,Wang D,Miyamoto S
Published figure using IgM monoclonal antibody (Product # 14-5790-82) in Flow Cytometry
Fri Feb 25 00:00:00 EST 2011
Regulatory B cell production of IL-10 inhibits lymphoma depletion during CD20 immunotherapy in mice.
The Journal of clinical investigation
Horikawa M,Minard-Colin V,Matsushita T,Tedder TF
14-5790 was used in Flow cytometry/Cell sorting to investigate whether heterogeneity in endogenous tissue CD20+ B cell depletion influences in vivo lymphoma therapy, showing that production of IL-10 inhibits lymphoma depletion.
Tue Nov 01 00:00:00 EDT 2011
Regulatory B cell production of IL-10 inhibits lymphoma depletion during CD20 immunotherapy in mice.
The Journal of clinical investigation
Horikawa M,Minard-Colin V,Matsushita T,Tedder TF
14-5790 was used in Flow cytometry/Cell sorting to investigate whether heterogeneity in endogenous tissue CD20+ B cell depletion influences in vivo lymphoma therapy, showing that production of IL-10 inhibits lymphoma depletion.
Tue Nov 01 00:00:00 EDT 2011
Transcription of preintegrated HIV-1 cDNA modulates cell surface expression of major histocompatibility complex class I via Nef.
Journal of virology
Sloan RD,Kuhl BD,Donahue DA,Roland A,Bar-Magen T,Wainberg MA
14-5790 was used in Flow cytometry/Cell sorting to suggest that Nef-mediated evasion of host immune responsiveness might be attributable to transcription from unintegrated viral DNA.
Tue Mar 01 00:00:00 EST 2011
Generation and evaluation of an IPTG-regulated version of Vav-gene promoter for mouse transgenesis.
PloS one
Grespi F,Ottina E,Yannoutsos N,Geley S,Villunger A
14-5790 was used in Flow cytometry/Cell sorting to evaluate the suitability of the lac-operon/lac-repressor (lacO/lacI) system for the regulation of the Vav-gene promoter, and the importance of IPTG.
Mon Mar 21 00:00:00 EDT 2011
Suppression of B-cell lymphomagenesis by the BH3-only proteins Bmf and Bad.
Blood
Frenzel A,Labi V,Chmelewskij W,Ploner C,Geley S,Fiegl H,Tzankov A,Villunger A
14-5790 was used in Flow cytometry/Cell sorting to demonstrate the potential of BH3-only proapoptotic Bcl-2 family members to regulate excessive lymphocyte proliferation.
Thu Feb 04 00:00:00 EST 2010
B-cell homeostasis requires complementary CD22 and BLyS/BR3 survival signals.
International immunology
Smith SH,Haas KM,Poe JC,Yanaba K,Ward CD,Migone TS,Tedder TF
14-5790 was used in Flow cytometry/Cell sorting to support a model whereby B cells must integrate varied signals, including those from the BLyS- BR3 axis, CD22-ligand binding and antigen-receptor-mediated tonic signaling for their homeostatic maintenance in vivo.
Sun Aug 01 00:00:00 EDT 2010
A critical role of TAK1 in B-cell receptor-mediated nuclear factor kappaB activation.
Blood
Schuman J,Chen Y,Podd A,Yu M,Liu HH,Wen R,Chen ZJ,Wang D
Published figure using IgM monoclonal antibody (Product # 14-5790-82) in Immunofluorescence
Thu May 07 00:00:00 EDT 2009
A critical role of TAK1 in B-cell receptor-mediated nuclear factor kappaB activation.
Blood
Schuman J,Chen Y,Podd A,Yu M,Liu HH,Wen R,Chen ZJ,Wang D
Published figure using IgM monoclonal antibody (Product # 14-5790-82) in Immunofluorescence
Thu May 07 00:00:00 EDT 2009
miR-19 is a key oncogenic component of mir-17-92.
Genes & development
Olive V,Bennett MJ,Walker JC,Ma C,Jiang I,Cordon-Cardo C,Li QJ,Lowe SW,Hannon GJ,He L
Published figure using IgM monoclonal antibody (Product # 14-5790-82) in Flow Cytometry
Tue Dec 15 00:00:00 EST 2009
Id1 represses osteoclast-dependent transcription and affects bone formation and hematopoiesis.
PloS one
Chan AS,Jensen KK,Skokos D,Doty S,Lederman HK,Kaplan RN,Rafii S,Rivella S,Lyden D
14-5790 was used in Flow cytometry/Cell sorting to identify Id1 as crucial for the dynamic cross-talk between bone and bone marrow haematopoietic cells.
Tue Nov 24 00:00:00 EST 2009
A regulatory B cell subset with a unique CD1dhiCD5+ phenotype controls T cell-dependent inflammatory responses.
Immunity
Yanaba K,Bouaziz JD,Haas KM,Poe JC,Fujimoto M,Tedder TF
14-5790 was used in Flow cytometry/Cell sorting to identify that CD1d(hi)CD5(+) B cells represent a unique subset of potent regulatory B cells.
Thu May 01 00:00:00 EDT 2008
Phospholipase Cgamma2 contributes to light-chain gene activation and receptor editing.
Molecular and cellular biology
Bai L,Chen Y,He Y,Dai X,Lin X,Wen R,Wang D
Published figure using IgM monoclonal antibody (Product # 14-5790-82) in Flow Cytometry
Sat Sep 01 00:00:00 EDT 2007
