Product References
A platinum@polymer-catechol nanobraker enables radio-immunotherapy for crippling melanoma tumorigenesis, angiogenesis, and radioresistance.
Bioactive materials
Li W,Yan J,Tian H,Li B,Wang G,Sang W,Zhang Z,Zhang X,Dai Y
Published figure using CD62L (L-Selectin) monoclonal antibody (Product # 17-0621-82) in Flow Cytometry
Sat Apr 01 00:00:00 EDT 2023
Microbiota-assisted iron uptake promotes immune tolerance in the intestine.
Nature communications
Zhu L,Li G,Liang Z,Qi T,Deng K,Yu J,Peng Y,Zheng J,Song Y,Chang X
Published figure using CD62L (L-Selectin) monoclonal antibody (Product # 17-0621-82) in Flow Cytometry
Mon May 15 00:00:00 EDT 2023
Lin28B-high breast cancer cells promote immune suppression in the lung pre-metastatic niche via exosomes and support cancer progression.
Nature communications
Qi M,Xia Y,Wu Y,Zhang Z,Wang X,Lu L,Dai C,Song Y,Xu K,Ji W,Zhan L
Published figure using CD62L (L-Selectin) monoclonal antibody (Product # 17-0621-82) in Flow Cytometry
Wed Feb 16 00:00:00 EST 2022
Amphiphile-CpG vaccination induces potent lymph node activation and COVID-19 immunity in mice and non-human primates.
NPJ vaccines
Seenappa LM,Jakubowski A,Steinbuck MP,Palmer E,Haqq CM,Carter C,Fontenot J,Villinger F,McNeil LK,DeMuth PC
Published figure using CD62L (L-Selectin) monoclonal antibody (Product # 17-0621-82) in Flow Cytometry
Fri Oct 28 00:00:00 EDT 2022
SPICE-Met: profiling and imaging energy metabolism at the single-cell level using a fluorescent reporter mouse.
The EMBO journal
Russo E,Lemaître F,Corre B,Chikina AS,Langa-Vives F,Bousso P
17-0621-82 was used in Flow cytometry/Cell sorting to describe SPICE-Met (Single-cell Profiling and Imaging of Cell Energy Metabolism), a method for profiling energy metabolism in single cells using flow cytometry or imaging.
Tue Oct 04 00:00:00 EDT 2022
Low immunogenicity of malaria pre-erythrocytic stages can be overcome by vaccination.
EMBO molecular medicine
Müller K,Gibbins MP,Roberts M,Reyes-Sandoval A,Hill AVS,Draper SJ,Matuschewski K,Silvie O,Hafalla JCR
Published figure using CD62L (L-Selectin) monoclonal antibody (Product # 17-0621-82) in Flow Cytometry
Fri Apr 09 00:00:00 EDT 2021
Sirt6 Regulates the Development of Medullary Thymic Epithelial Cells and Contributes to the Establishment of Central Immune Tolerance.
Frontiers in cell and developmental biology
Zhang Q,Liang Z,Zhang J,Lei T,Dong X,Su H,Chen Y,Zhang Z,Tan L,Zhao Y
Published figure using CD62L (L-Selectin) monoclonal antibody (Product # 17-0621-82) in Flow Cytometry
Wed Apr 21 00:00:00 EDT 2021
Trichinella spiralis Paramyosin Induces Colonic Regulatory T Cells to Mitigate Inflammatory Bowel Disease.
Frontiers in cell and developmental biology
Hao C,Wang W,Zhan B,Wang Z,Huang J,Sun X,Zhu X
Published figure using CD62L (L-Selectin) monoclonal antibody (Product # 17-0621-82) in Flow Cytometry
Tue Aug 03 00:00:00 EDT 2021
CD8+ T cells in the central nervous system of mice with herpes simplex infection are highly activated and express high levels of CCR5 and CXCR3.
Journal of neurovirology
Lind L,Svensson A,Thörn K,Krzyzowska M,Eriksson K
Published figure using CD62L (L-Selectin) monoclonal antibody (Product # 17-0621-82) in Flow Cytometry
Mon Feb 01 00:00:00 EST 2021
cDC1 Dependent Accumulation of Memory T Cells Is Required for Chronic Autoimmune Inflammation in Murine Testis.
Frontiers in immunology
Jing Y,Cao M,Zhang B,Long X,Wang X
Published figure using CD62L (L-Selectin) monoclonal antibody (Product # 17-0621-82) in Flow Cytometry
Fri Sep 24 00:00:00 EDT 2021
cDC1 Dependent Accumulation of Memory T Cells Is Required for Chronic Autoimmune Inflammation in Murine Testis.
Frontiers in immunology
Jing Y,Cao M,Zhang B,Long X,Wang X
Published figure using CD62L (L-Selectin) monoclonal antibody (Product # 17-0621-82) in Flow Cytometry
Fri Sep 24 00:00:00 EDT 2021
Evaluation of DNA-Launched Virus-Like Particle Vaccines in an Immune Competent Mouse Model of Chikungunya Virus Infection.
Vaccines
Rayner JO,Kim JH,Roberts RW,Wood RR,Fouty B,Solodushko V
Published figure using CD62L (L-Selectin) monoclonal antibody (Product # 17-0621-82) in Flow Cytometry
Fri Apr 02 00:00:00 EDT 2021
PI3Kδ coordinates transcriptional, chromatin, and metabolic changes to promote effector CD8+ T cells at the expense of central memory.
Cell reports
Cannons JL,Villarino AV,Kapnick SM,Preite S,Shih HY,Gomez-Rodriguez J,Kaul Z,Shibata H,Reilley JM,Huang B,Handon R,McBain IT,Gossa S,Wu T,Su HC,McGavern DB,O'Shea JJ,McGuire PJ,Uzel G,Schwartzberg PL
Published figure using CD62L (L-Selectin) monoclonal antibody (Product # 17-0621-82) in Flow Cytometry
Tue Oct 12 00:00:00 EDT 2021
Synchronous effects of targeted mitochondrial complex I inhibitors on tumor and immune cells abrogate melanoma progression.
iScience
AbuEid M,McAllister DM,McOlash L,Harwig MC,Cheng G,Drouillard D,Boyle KA,Hardy M,Zielonka J,Johnson BD,Hill RB,Kalyanaraman B,Dwinell MB
Published figure using CD62L (L-Selectin) monoclonal antibody (Product # 17-0621-82) in Flow Cytometry
Fri Jun 25 00:00:00 EDT 2021
Theranostic near-infrared-IIb emitting nanoprobes for promoting immunogenic radiotherapy and abscopal effects against cancer metastasis.
Nature communications
Li H,Wang M,Huang B,Zhu SW,Zhou JJ,Chen DR,Cui R,Zhang M,Sun ZJ
Published figure using CD62L (L-Selectin) monoclonal antibody (Product # 17-0621-82) in Flow Cytometry
Thu Dec 09 00:00:00 EST 2021
Targeting Phosphatidylserine Enhances the Anti-tumor Response to Tumor-Directed Radiation Therapy in a Preclinical Model of Melanoma.
Cell reports
Budhu S,Giese R,Gupta A,Fitzgerald K,Zappasodi R,Schad S,Hirschhorn D,Campesato LF,De Henau O,Gigoux M,Liu C,Mazo G,Deng L,Barker CA,Wolchok JD,Merghoub T
Published figure using CD62L (L-Selectin) monoclonal antibody (Product # 17-0621-82) in Flow Cytometry
Tue Jan 12 00:00:00 EST 2021
Type 1 Cytotoxic T Cells Increase in Placenta after Intrauterine Inflammation.
Frontiers in immunology
Liu J,Liu Y,Panda S,Liu A,Lei J,Burd I
Published figure using CD62L (L-Selectin) monoclonal antibody (Product # 17-0621-82) in Flow Cytometry
Fri Dec 17 00:00:00 EST 2021
Near-infrared photoimmunotherapy targeting human-EGFR in a mouse tumor model simulating current and future clinical trials.
EBioMedicine
Okada R,Furusawa A,Vermeer DW,Inagaki F,Wakiyama H,Kato T,Nagaya T,Choyke PL,Spanos WC,Allen CT,Kobayashi H
17-0621-82 was used in Flow Cytometry to conclude that combined hEGFR and CD25-targeted NIR-PIT is a promising treatment for hEGFR expressing cancers in which Treg cells play an immunosuppressive role.
Sat May 01 00:00:00 EDT 2021
Near-infrared photoimmunotherapy targeting human-EGFR in a mouse tumor model simulating current and future clinical trials.
EBioMedicine
Okada R,Furusawa A,Vermeer DW,Inagaki F,Wakiyama H,Kato T,Nagaya T,Choyke PL,Spanos WC,Allen CT,Kobayashi H
17-0621-82 was used in Flow Cytometry to conclude that combined hEGFR and CD25-targeted NIR-PIT is a promising treatment for hEGFR expressing cancers in which Treg cells play an immunosuppressive role.
Sat May 01 00:00:00 EDT 2021
Inhibition of TLR4 signaling protects mice from sensory and motor dysfunction in an animal model of autoimmune peripheral neuropathy.
Journal of neuroinflammation
Oladiran O,Shi XQ,Yang M,Fournier S,Zhang J
Published figure using CD62L (L-Selectin) monoclonal antibody (Product # 17-0621-82) in Flow Cytometry
Mon Mar 22 00:00:00 EDT 2021
STING Activated Tumor-Intrinsic Type I Interferon Signaling Promotes CXCR3 Dependent Antitumor Immunity in Pancreatic Cancer.
Cellular and molecular gastroenterology and hepatology
Vonderhaar EP,Barnekow NS,McAllister D,McOlash L,Eid MA,Riese MJ,Tarakanova VL,Johnson BD,Dwinell MB
Published figure using CD62L (L-Selectin) monoclonal antibody (Product # 17-0621-82) in Flow Cytometry
Mon Jan 24 00:00:00 EST 2022
A nanounit strategy reverses immune suppression of exosomal PD-L1 and is associated with enhanced ferroptosis.
Nature communications
Wang G,Xie L,Li B,Sang W,Yan J,Li J,Tian H,Li W,Zhang Z,Tian Y,Dai Y
Published figure using CD62L (L-Selectin) monoclonal antibody (Product # 17-0621-82) in Flow Cytometry
Thu Sep 30 00:00:00 EDT 2021
Graded RhoA GTPase Expression in Treg Cells Distinguishes Tumor Immunity From Autoimmunity.
Frontiers in immunology
Kalim KW,Yang JQ,Modur V,Nguyen P,Li Y,Zheng Y,Guo F
Published figure using CD62L (L-Selectin) monoclonal antibody (Product # 17-0621-82) in Flow Cytometry
Tue Jan 11 00:00:00 EST 2022
Hepatocyte-specific glucose-6-phosphatase deficiency disturbs platelet aggregation and decreases blood monocytes upon fasting-induced hypoglycemia.
Molecular metabolism
La Rose AM,Bazioti V,Hoogerland JA,Svendsen AF,Groenen AG,van Faassen M,Rutten MGS,Kloosterhuis NJ,Dethmers-Ausema B,Nijland JH,Mithieux G,Rajas F,Kuipers F,Lukens MV,Soehnlein O,Oosterveer MH,Westerterp M
17-0621-82 was used in Flow Cytometry to evaluate the effect of glycemic control on leukocyte levels and coagulation in glycogen storage disease type 1a.
Mon Nov 01 00:00:00 EDT 2021
Analysis of T cells in mouse lymphoid tissue and blood with flow cytometry.
STAR protocols
Skordos I,Demeyer A,Beyaert R
Published figure using CD62L (L-Selectin) monoclonal antibody (Product # 17-0621-82) in Flow Cytometry
Fri Mar 19 00:00:00 EDT 2021
Oxygen-Enriched Metal-Phenolic X-Ray Nanoprocessor for Cancer Radio-Radiodynamic Therapy in Combination with Checkpoint Blockade Immunotherapy.
Advanced science (Weinheim, Baden-Wurttemberg, Germany)
Sang W,Xie L,Wang G,Li J,Zhang Z,Li B,Guo S,Deng CX,Dai Y
17-0621 was used in Flow cytometry/Cell sorting to presents a multifunctional metal-phenolic nanoplatform for efficient X-ray mediated RT-RDT in combination with immunotherapy and may provide a new therapeutic option for cancer treatment.
Mon Feb 01 00:00:00 EST 2021
Insulin-Like Growth Factors Are Key Regulators of T Helper 17 Regulatory T Cell Balance in Autoimmunity.
Immunity
DiToro D,Harbour SN,Bando JK,Benavides G,Witte S,Laufer VA,Moseley C,Singer JR,Frey B,Turner H,Bruning J,Darley-Usmar V,Gao M,Conover C,Hatton RD,Frank S,Colonna M,Weaver CT
17-0621 was used in Flow cytometry/Cell sorting to show that, among effector T cell subsets, Th17 and Treg cells selectively expressed multiple components of the IGF system.
Tue Apr 14 00:00:00 EDT 2020
Regulatory T Cell-Derived TGF-β1 Controls Multiple Checkpoints Governing Allergy and Autoimmunity.
Immunity
Turner JA,Stephen-Victor E,Wang S,Rivas MN,Abdel-Gadir A,Harb H,Cui Y,Fanny M,Charbonnier LM,Fong JJH,Benamar M,Wang L,Burton OT,Bansal K,Bry L,Zhu C,Li QZ,Clement RL,Oettgen HC,Crestani E,Rachid R,Sage PT,Chatila TA
17-0621-82 was used in Flow Cytometry to show that Treg cells in food allergy (FA) had decreased expression of transforming growth factor beta 1 (TGF-β1) because of interleukin-4 (IL-4)- and signal transducer and activator of transciription-6 (STAT6)-dependent inhibition of Tgfb1 transcription.
Tue Dec 15 00:00:00 EST 2020
Placental endovascular extravillous trophoblasts (enEVTs) educate maternal T-cell differentiation along the maternal-placental circulation.
Cell proliferation
Ma Y,Yang Q,Fan M,Zhang L,Gu Y,Jia W,Li Z,Wang F,Li YX,Wang J,Li R,Shao X,Wang YL
17-0621 was used in Flow cytometry/Cell sorting to study the TGF-β1 expression and distribution of regulatory T cells (Tregs) along the placental-maternal circulation route.
Fri May 01 00:00:00 EDT 2020
B Cell Diversification Is Uncoupled from SAP-Mediated Selection Forces in Chronic Germinal Centers within Peyer's Patches.
Cell reports
Biram A,Winter E,Denton AE,Zaretsky I,Dassa B,Bemark M,Linterman MA,Yaari G,Shulman Z
Published figure using CD62L (L-Selectin) monoclonal antibody (Product # 17-0621-82) in Flow Cytometry
Tue Feb 11 00:00:00 EST 2020
Inhibition of IRF4 in dendritic cells by PRR-independent and -dependent signals inhibit Th2 and promote Th17 responses.
eLife
Lee J,Zhang J,Chung YJ,Kim JH,Kook CM,González-Navajas JM,Herdman DS,Nürnberg B,Insel PA,Corr M,Mo JH,Tao A,Yasuda K,Rifkin IR,Broide DH,Sciammas R,Webster NJ,Raz E
Published figure using CD62L (L-Selectin) monoclonal antibody (Product # 17-0621-82) in Flow Cytometry
Tue Feb 04 00:00:00 EST 2020
Attenuation of TCR-induced transcription by Bach2 controls regulatory T cell differentiation and homeostasis.
Nature communications
Sidwell T,Liao Y,Garnham AL,Vasanthakumar A,Gloury R,Blume J,Teh PP,Chisanga D,Thelemann C,de Labastida Rivera F,Engwerda CR,Corcoran L,Kometani K,Kurosaki T,Smyth GK,Shi W,Kallies A
Published figure using CD62L (L-Selectin) monoclonal antibody (Product # 17-0621-82) in Flow Cytometry
Tue Jan 14 00:00:00 EST 2020
Diverse CD8 T Cell Responses to Viral Infection Revealed by the Collaborative Cross.
Cell reports
Martin MD,Sompallae R,Winborn CS,Harty JT,Badovinac VP
17-0621 was used in Flow cytometry/Cell sorting to advance the utility of the Collaborative Cross (CC) as a tool to analyze the immune response to viral infection.
Tue Apr 14 00:00:00 EDT 2020
Localized cocktail chemoimmunotherapy after in situ gelation to trigger robust systemic antitumor immune responses.
Science advances
Chao Y,Liang C,Tao H,Du Y,Wu D,Dong Z,Jin Q,Chen G,Xu J,Xiao Z,Chen Q,Wang C,Chen J,Liu Z
17-0621-82 was used in Flow Cytometry to report several "cocktail" therapeutic formulations by mixing immunogenic cell death (ICD)-inducing chemotherapeutics and immune adjuvants together with alginate (ALG) for localized chemoimmunotherapy.
Sun Mar 01 00:00:00 EST 2020
Localized cocktail chemoimmunotherapy after in situ gelation to trigger robust systemic antitumor immune responses.
Science advances
Chao Y,Liang C,Tao H,Du Y,Wu D,Dong Z,Jin Q,Chen G,Xu J,Xiao Z,Chen Q,Wang C,Chen J,Liu Z
17-0621-82 was used in Flow Cytometry to report several "cocktail" therapeutic formulations by mixing immunogenic cell death (ICD)-inducing chemotherapeutics and immune adjuvants together with alginate (ALG) for localized chemoimmunotherapy.
Sun Mar 01 00:00:00 EST 2020
Gasdermin D in peripheral myeloid cells drives neuroinflammation in experimental autoimmune encephalomyelitis.
The Journal of experimental medicine
Li S,Wu Y,Yang D,Wu C,Ma C,Liu X,Moynagh PN,Wang B,Hu G,Yang S
17-0621-82 was used in Flow Cytometry to study how GSDMD deficiency in peripheral myeloid cells impaired the infiltration of immune cells into the CNS, leading to the suppression of neuroinflammation and demyelination.
Mon Nov 04 00:00:00 EST 2019
ER stress-induced mediator C/EBP homologous protein thwarts effector T cell activity in tumors through T-bet repression.
Nature communications
Cao Y,Trillo-Tinoco J,Sierra RA,Anadon C,Dai W,Mohamed E,Cen L,Costich TL,Magliocco A,Marchion D,Klar R,Michel S,Jaschinski F,Reich RR,Mehrotra S,Cubillos-Ruiz JR,Munn DH,Conejo-Garcia JR,Rodriguez PC
Published figure using CD62L (L-Selectin) monoclonal antibody (Product # 17-0621-82) in Flow Cytometry
Wed Mar 20 00:00:00 EDT 2019
Pulsatile MEK Inhibition Improves Anti-tumor Immunity and T Cell Function in Murine Kras Mutant Lung Cancer.
Cell reports
Choi H,Deng J,Li S,Silk T,Dong L,Brea EJ,Houghton S,Redmond D,Zhong H,Boiarsky J,Akbay EA,Smith PD,Merghoub T,Wong KK,Wolchok JD
Published figure using CD62L (L-Selectin) monoclonal antibody (Product # 17-0621-82) in Flow Cytometry
Tue Apr 16 00:00:00 EDT 2019
Activated Peyer's patch B cells sample antigen directly from M cells in the subepithelial dome.
Nature communications
Komban RJ,Strömberg A,Biram A,Cervin J,Lebrero-Fernández C,Mabbott N,Yrlid U,Shulman Z,Bemark M,Lycke N
Published figure using CD62L (L-Selectin) monoclonal antibody (Product # 17-0621-82) in Flow Cytometry
Mon Jun 03 00:00:00 EDT 2019
Autophagy Regulation of Metabolism Is Required for CD8+ T Cell Anti-tumor Immunity.
Cell reports
DeVorkin L,Pavey N,Carleton G,Comber A,Ho C,Lim J,McNamara E,Huang H,Kim P,Zacharias LG,Mizushima N,Saitoh T,Akira S,Beckham W,Lorzadeh A,Moksa M,Cao Q,Murthy A,Hirst M,DeBerardinis RJ,Lum JJ
17-0621 was used in Flow cytometry/Cell sorting to demonstrate a cell-autonomous role for autophagy in the regulation of CD8+ T-cell-mediated control of tumors.
Tue Apr 09 00:00:00 EDT 2019
Checkpoint blockade and nanosonosensitizer-augmented noninvasive sonodynamic therapy combination reduces tumour growth and metastases in mice.
Nature communications
Yue W,Chen L,Yu L,Zhou B,Yin H,Ren W,Liu C,Guo L,Zhang Y,Sun L,Zhang K,Xu H,Chen Y
17-0621 was used in Flow cytometry/Cell sorting to demonstrate how a combination of nanosonosensitiser-augmented sonodynamic and anti-PD-L1 checkpoint blockade therapy deliver highly efficient tumour therapy in mice.
Thu May 02 00:00:00 EDT 2019
Bacteroides fragilis polysaccharide A induces IL-10 secreting B and T cells that prevent viral encephalitis.
Nature communications
Ramakrishna C,Kujawski M,Chu H,Li L,Mazmanian SK,Cantin EM
17-0621 was used in Flow cytometry/Cell sorting to study polysaccharide A as an immunomodulatory symbiosis factor whcih coordinates anti-inflammatory responses during viral infections.
Tue May 14 00:00:00 EDT 2019
MTOR signaling is essential for the development of thymic epithelial cells and the induction of central immune tolerance.
Autophagy
Liang Z,Zhang L,Su H,Luan R,Na N,Sun L,Zhao Y,Zhang X,Zhang Q,Li J,Zhang L,Zhao Y
Published figure using CD62L (L-Selectin) monoclonal antibody (Product # 17-0621-82) in Flow Cytometry
Fri Mar 22 00:00:00 EDT 2019
In Vitro Priming of Adoptively Transferred T Cells with a RORγ Agonist Confers Durable Memory and Stemness In Vivo.
Cancer research
Hu X,Majchrzak K,Liu X,Wyatt MM,Spooner CJ,Moisan J,Zou W,Carter LL,Paulos CM
17-0621 was used in Flow cytometry/Cell sorting to demonstrate that addition of a synthetic, small-molecule RORγ agonist during ex vivo expansion potentiates the anti-tumour activity of human Th17 and Tc17 cells redirected with a chimeric antigen receptor.
Sun Jul 15 00:00:00 EDT 2018
C5aR1 regulates T follicular helper differentiation and chronic graft-versus-host disease bronchiolitis obliterans.
JCI insight
Verghese DA,Chun N,Paz K,Fribourg M,Woodruff TM,Flynn R,Hu Y,Xiong H,Zhang W,Yi Z,Du J,Blazar BR,Heeger PS
Published figure using CD62L (L-Selectin) monoclonal antibody (Product # 17-0621-82) in Flow Cytometry
Thu Dec 20 00:00:00 EST 2018
Helminth-induced IL-4 expands bystander memory CD8+ T cells for early control of viral infection.
Nature communications
Rolot M,Dougall AM,Chetty A,Javaux J,Chen T,Xiao X,Machiels B,Selkirk ME,Maizels RM,Hokke C,Denis O,Brombacher F,Vanderplasschen A,Gillet L,Horsnell WGC,Dewals BG
Published figure using CD62L (L-Selectin) monoclonal antibody (Product # 17-0621-82) in Flow Cytometry
Tue Oct 30 00:00:00 EDT 2018
Repeated Antigen Exposure Extends the Durability of Influenza-Specific Lung-Resident Memory CD8+ T Cells and Heterosubtypic Immunity.
Cell reports
Van Braeckel-Budimir N,Varga SM,Badovinac VP,Harty JT
17-0621 was used in Flow cytometry/Cell sorting to demonstrate that, relative to single virus exposure, repeated antigen exposure dramatically alters the dynamics of influenza-specific lung-resident primary memory CD8+ T cell populations.
Tue Sep 25 00:00:00 EDT 2018
A stochastic epigenetic switch controls the dynamics of T-cell lineage commitment.
eLife
Ng KK,Yui MA,Mehta A,Siu S,Irwin B,Pease S,Hirose S,Elowitz MB,Rothenberg EV,Kueh HY
17-0621 was used in Flow cytometry/Cell sorting to study the activation of Bcl11b, which controls T-cell fate commitment.
Tue Nov 20 00:00:00 EST 2018
Stability and function of regulatory T cells expressing the transcription factor T-bet.
Nature
Levine AG,Mendoza A,Hemmers S,Moltedo B,Niec RE,Schizas M,Hoyos BE,Putintseva EV,Chaudhry A,Dikiy S,Fujisawa S,Chudakov DM,Treuting PM,Rudensky AY
Published figure using CD62L (L-Selectin) monoclonal antibody (Product # 17-0621-82) in Flow Cytometry
Thu Jun 15 00:00:00 EDT 2017
Antibody Tumor Targeting Is Enhanced by CD27 Agonists through Myeloid Recruitment.
Cancer cell
Turaj AH,Hussain K,Cox KL,Rose-Zerilli MJJ,Testa J,Dahal LN,Chan HTC,James S,Field VL,Carter MJ,Kim HJ,West JJ,Thomas LJ,He LZ,Keler T,Johnson PWM,Al-Shamkhani A,Thirdborough SM,Beers SA,Cragg MS,Glennie MJ,Lim SH
Mon Dec 11 00:00:00 EST 2017
Cholesterol Accumulation in Dendritic Cells Links the Inflammasome to Acquired Immunity.
Cell metabolism
Westerterp M,Gautier EL,Ganda A,Molusky MM,Wang W,Fotakis P,Wang N,Randolph GJ,D'Agati VD,Yvan-Charvet L,Tall AR
17-0621 was used in Flow cytometry/Cell sorting to identify an essential role of DC cholesterol efflux pathways in maintaining immune tolerance.
Tue Jun 06 00:00:00 EDT 2017
A Stat6/Pten Axis Links Regulatory T Cells with Adipose Tissue Function.
Cell metabolism
Kälin S,Becker M,Ott VB,Serr I,Hosp F,Mollah MMH,Keipert S,Lamp D,Rohner-Jeanrenaud F,Flynn VK,Scherm MG,Nascimento LFR,Gerlach K,Popp V,Dietzen S,Bopp T,Krishnamurthy P,Kaplan MH,Serrano M,Woods SC,Tripal P,Palmisano R,Jastroch M,Blüher M,Wolfrum C,Weigmann B,Ziegler AG,Mann M,Tschöp MH,Daniel C
17-0621-82 was used in Flow Cytometry to study the link between adipose tissue function and regulatory T cells.
Tue Sep 05 00:00:00 EDT 2017
A Predictive Model for Selective Targeting of the Warburg Effect through GAPDH Inhibition with a Natural Product.
Cell metabolism
Liberti MV,Dai Z,Wardell SE,Baccile JA,Liu X,Gao X,Baldi R,Mehrmohamadi M,Johnson MO,Madhukar NS,Shestov AA,Chio IIC,Elemento O,Rathmell JC,Schroeder FC,McDonnell DP,Locasale JW
17-0621 was used in Flow cytometry/Cell sorting to develop a predictive model for selective targeting of the Warburg effect.
Tue Oct 03 00:00:00 EDT 2017
Epithelial-Cell-Derived Phospholipase A2 Group 1B Is an Endogenous Anthelmintic.
Cell host & microbe
Entwistle LJ,Pelly VS,Coomes SM,Kannan Y,Perez-Lloret J,Czieso S,Silva Dos Santos M,MacRae JI,Collinson L,Sesay A,Nikolov N,Metidji A,Helmby H,Hui DY,Wilson MS
17-0621 was used in Flow cytometry/Cell sorting to uncover epithelial-cell-derived Pla2g1b as an essential mediator of helminth killing.
Wed Oct 11 00:00:00 EDT 2017
Excessive expression of miR-27 impairs Treg-mediated immunological tolerance.
The Journal of clinical investigation
Cruz LO,Hashemifar SS,Wu CJ,Cho S,Nguyen DT,Lin LL,Khan AA,Lu LF
Published figure using CD62L (L-Selectin) monoclonal antibody (Product # 17-0621-82) in Flow Cytometry
Wed Feb 01 00:00:00 EST 2017
Egr2 and 3 control adaptive immune responses by temporally uncoupling expansion from T cell differentiation.
The Journal of experimental medicine
Miao T,Symonds ALJ,Singh R,Symonds JD,Ogbe A,Omodho B,Zhu B,Li S,Wang P
Published figure using CD62L (L-Selectin) monoclonal antibody (Product # 17-0621-82) in Flow Cytometry
Mon Jun 05 00:00:00 EDT 2017
Nimodipine fosters remyelination in a mouse model of multiple sclerosis and induces microglia-specific apoptosis.
Proceedings of the National Academy of Sciences of the United States of America
Schampel A,Volovitch O,Koeniger T,Scholz CJ,Jörg S,Linker RA,Wischmeyer E,Wunsch M,Hell JW,Ergün S,Kuerten S
17-0621 was used in Flow cytometry/Cell sorting to show that nimodipine application generates a favourable environment for regenerative processes and could be a treatment option for multiple sclerosis.
Tue Apr 18 00:00:00 EDT 2017
Engineered erythrocytes covalently linked to antigenic peptides can protect against autoimmune disease.
Proceedings of the National Academy of Sciences of the United States of America
Pishesha N,Bilate AM,Wibowo MC,Huang NJ,Li Z,Deshycka R,Bousbaine D,Li H,Patterson HC,Dougan SK,Maruyama T,Lodish HF,Ploegh HL
17-0621-82 was used in Flow cytometry/Cell sorting to show that transfusion of red blood cells expressing self-antigen epitopes can alleviate and even prevent signs of disease in experimental autoimmune encephalomyelitis, as well as maintain normoglycemia in a mouse model of type 1 diabetes.
Tue Mar 21 00:00:00 EDT 2017
Role of Nuclear Factor (Erythroid-Derived 2)-Like 2 Signaling for Effects of Fumaric Acid Esters on Dendritic Cells.
Frontiers in immunology
Hammer A,Waschbisch A,Knippertz I,Zinser E,Berg J,Jörg S,Kuhbandner K,David C,Pi J,Bayas A,Lee DH,Haghikia A,Gold R,Steinkasserer A,Linker RA
Wed Nov 20 00:00:00 EST 2019
Peripheral administration of the soluble TNF inhibitor XPro1595 modifies brain immune cell profiles, decreases beta-amyloid plaque load, and rescues impaired long-term potentiation in 5xFAD mice.
Neurobiology of disease
MacPherson KP,Sompol P,Kannarkat GT,Chang J,Sniffen L,Wildner ME,Norris CM,Tansey MG
Published figure using CD62L (L-Selectin) monoclonal antibody (Product # 17-0621-82) in Flow Cytometry
Thu Jun 01 00:00:00 EDT 2017
The Ox40/Ox40 Ligand Pathway Promotes Pathogenic Th Cell Responses, Plasmablast Accumulation, and Lupus Nephritis in NZB/W F1 Mice.
Journal of immunology (Baltimore, Md. : 1950)
Sitrin J,Suto E,Wuster A,Eastham-Anderson J,Kim JM,Austin CD,Lee WP,Behrens TW
Published figure using CD62L (L-Selectin) monoclonal antibody (Product # 17-0621-82) in Flow Cytometry
Tue Aug 15 00:00:00 EDT 2017
Impairment of CCR6+ and CXCR3+ Th Cell Migration in HIV-1 Infection Is Rescued by Modulating Actin Polymerization.
Journal of immunology (Baltimore, Md. : 1950)
Cecchinato V,Bernasconi E,Speck RF,Proietti M,Sauermann U,D'Agostino G,Danelon G,Rezzonico Jost T,Grassi F,Raeli L,Schöni-Affolter F,Stahl-Hennig C,Uguccioni M
17-0621 was used in Flow cytometry/Cell sorting to investigate how actin polymerization modulation restores lymphocyte migration in response to chemokines in HIV-1 infection.
Sun Jan 01 00:00:00 EST 2017
Differential effect of Platelet Endothelial Cell Adhesion Molecule-1 (PECAM-1) on leukocyte infiltration during contact hypersensitivity responses.
PeerJ
Early M,Schroeder WG,Unnithan R,Gilchrist JM,Muller WA,Schenkel A
Mon Dec 14 00:00:00 EST 2020
Batf3-dependent CD8α+ Dendritic Cells Aggravates Atherosclerosis via Th1 Cell Induction and Enhanced CCL5 Expression in Plaque Macrophages.
EBioMedicine
Li Y,Liu X,Duan W,Tian H,Zhu G,He H,Yao S,Yi S,Song W,Tang H
Published figure using CD62L (L-Selectin) monoclonal antibody (Product # 17-0621-82) in Flow Cytometry
Sat Apr 01 00:00:00 EDT 2017
Extrafollicular CD4+ T-B interactions are sufficient for inducing autoimmune-like chronic graft-versus-host disease.
Nature communications
Deng R,Hurtz C,Song Q,Yue C,Xiao G,Yu H,Wu X,Muschen M,Forman S,Martin PJ,Zeng D
Published figure using CD62L (L-Selectin) monoclonal antibody (Product # 17-0621-82) in Flow Cytometry
Tue Oct 17 00:00:00 EDT 2017
MyD88-dependent pro-interleukin-1β induction in dendritic cells exposed to food-grade synthetic amorphous silica.
Particle and fibre toxicology
Winkler HC,Kornprobst J,Wick P,von Moos LM,Trantakis I,Schraner EM,Bathke B,Hochrein H,Suter M,Naegeli H
Fri Jun 23 00:00:00 EDT 2017
Identification of Zika virus epitopes reveals immunodominant and protective roles for dengue virus cross-reactive CD8+ T cells.
Nature microbiology
Wen J,Tang WW,Sheets N,Ellison J,Sette A,Kim K,Shresta S
17-0621 was used in Flow cytometry/Cell sorting to demonstrate both an altered immunodominance pattern in the DENV-immune setting relative to naive, as well as a protective role for epitope-specific CD8+ T cells against ZIKV.
Mon Mar 13 00:00:00 EDT 2017
Impact of combined sodium chloride and saturated long-chain fatty acid challenge on the differentiation of T helper cells in neuroinflammation.
Journal of neuroinflammation
Hammer A,Schliep A,Jörg S,Haghikia A,Gold R,Kleinewietfeld M,Müller DN,Linker RA
17-0621 was used in Flow cytometry/Cell sorting to demonstrate that sodium chloride and lauric acid have an additive effect on T helper cell polarisation and responses in autoimmune neuroinflammation.
Tue Sep 12 00:00:00 EDT 2017
NKT sublineage specification and survival requires the ubiquitin-modifying enzyme TNFAIP3/A20.
The Journal of experimental medicine
Drennan MB,Govindarajan S,Verheugen E,Coquet JM,Staal J,McGuire C,Taghon T,Leclercq G,Beyaert R,van Loo G,Lambrecht BN,Elewaut D
17-0621 was used in Flow cytometry/Cell sorting to show that negative regulation of TCR signalling during NKT development controls the differentiation and survival of NKT1 and NKT2 cells.
Mon Sep 19 00:00:00 EDT 2016
Foxp3(+) T cells expressing RORγt represent a stable regulatory T-cell effector lineage with enhanced suppressive capacity during intestinal inflammation.
Mucosal immunology
Yang BH,Hagemann S,Mamareli P,Lauer U,Hoffmann U,Beckstette M,Föhse L,Prinz I,Pezoldt J,Suerbaum S,Sparwasser T,Hamann A,Floess S,Huehn J,Lochner M
17-0621 was used in Flow cytometry/Cell sorting to demonstrate that Foxp3(+) T cells expressing retinoic acid-related orphan receptor-γt, represent a stable regulatory T cell lineage with a highly suppressive phenotype in vivo.
Tue Mar 01 00:00:00 EST 2016
Mast cell depletion in the preclinical phase of collagen-induced arthritis reduces clinical outcome by lowering the inflammatory cytokine profile.
Arthritis research & therapy
van der Velden D,Lagraauw HM,Wezel A,Launay P,Kuiper J,Huizinga TW,Toes RE,Bot I,Stoop JN
17-0621 was used in Flow cytometry/Cell sorting to suggest that mast cells may play a role in the regulation of the adaptive immune response during the development of arthritis.
Mon Jun 13 00:00:00 EDT 2016
Targeting of Ly9 (CD229) Disrupts Marginal Zone and B1 B Cell Homeostasis and Antibody Responses.
Journal of immunology (Baltimore, Md. : 1950)
Cuenca M,Romero X,Sintes J,Terhorst C,Engel P
17-0621 was used in Flow cytometry/Cell sorting to investigate the role of Ly9 in the development and function of innate T lymphocytes, showing that targeting Ly9 disrupts marginal zone and B1 B cell homeostasis.
Fri Jan 15 00:00:00 EST 2016
B cell-derived transforming growth factor-β1 expression limits the induction phase of autoimmune neuroinflammation.
Scientific reports
Bjarnadóttir K,Benkhoucha M,Merkler D,Weber MS,Payne NL,Bernard CCA,Molnarfi N,Lalive PH
17-0621-82 was used in Flow Cytometry to test the role for transforming growth factor-β1 expression in regulatory B cell function in autoimmune neuroinflammation.
Thu Oct 06 00:00:00 EDT 2016
Type 1 diabetes vaccine candidates promote human Foxp3(+)Treg induction in humanized mice.
Nature communications
Serr I,Fürst RW,Achenbach P,Scherm MG,Gökmen F,Haupt F,Sedlmeier EM,Knopff A,Shultz L,Willis RA,Ziegler AG,Daniel C
17-0621 was used in Flow cytometry/Cell sorting to show induced human Tregs show increased expression of Treg signature genes such as Foxp3, CTLA4, IL-2Rα and TIGIT.
Tue Mar 15 00:00:00 EDT 2016
Tumour suppressor death-associated protein kinase targets cytoplasmic HIF-1α for Th17 suppression.
Nature communications
Chou TF,Chuang YT,Hsieh WC,Chang PY,Liu HY,Mo ST,Hsu TS,Miaw SC,Chen RH,Kimchi A,Lai MZ
17-0621 was used in Flow cytometry/Cell sorting to study tumour suppressor death-associated protein kinases as treatments for Th17-associated inflammatory diseases.
Fri Jun 17 00:00:00 EDT 2016
Photothermal therapy with immune-adjuvant nanoparticles together with checkpoint blockade for effective cancer immunotherapy.
Nature communications
Chen Q,Xu L,Liang C,Wang C,Peng R,Liu Z
17-0621 was used in Immunohistochemistry to investigate the use of immuneadjuvant nanoparticles for photothermal tumour ablation in mice and their potential for cancer immunotherapy.
Fri Oct 21 00:00:00 EDT 2016
Quantitative and Qualitative Analysis of Bone Marrow CD8(+) T Cells from Different Bones Uncovers a Major Contribution of the Bone Marrow in the Vertebrae.
Frontiers in immunology
Geerman S,Hickson S,Brasser G,Pascutti MF,Nolte MA
17-0621 was used in Flow cytometry/Cell sorting to suggest that in respect to CD8(+) T cells, BM harvested from a single bone is a fair reflection of the rest of the BM present in the murine body.
Thu Jan 21 00:00:00 EST 2016
A novel Cd8-cis-regulatory element preferentially directs expression in CD44hiCD62L+ CD8+ T cells and in CD8αα+ dendritic cells.
Journal of leukocyte biology
Sakaguchi S,Hombauer M,Hassan H,Tanaka H,Yasmin N,Naoe Y,Bilic I,Moser MA,Hainberger D,Mayer H,Seiser C,Bergthaler A,Taniuchi I,Ellmeier W
17-0621 was used in Flow cytometry/Cell sorting to identify a novel Cd8 enhancer that directs expression in CD44(hi)CD62L(+) CD8(+) T cells, including innate-like and antigen-specific effector/memory CD8(+) T cells and in CD8αα(+) DCs.
Wed Apr 01 00:00:00 EDT 2015
The Flavonoid Isoliquiritigenin Reduces Lung Inflammation and Mouse Morbidity during Influenza Virus Infection.
Antimicrobial agents and chemotherapy
Traboulsi H,Cloutier A,Boyapelly K,Bonin MA,Marsault É,Cantin AM,Richter MV
17-0621 was used in Flow cytometry/Cell sorting to investigate the anti-inflammatory and antiviral activities of isoliquiritigenin during influenza virus infection.
Thu Oct 01 00:00:00 EDT 2015
Unexpected Role for Adaptive αβTh17 Cells in Acute Respiratory Distress Syndrome.
Journal of immunology (Baltimore, Md. : 1950)
Li JT,Melton AC,Su G,Hamm DE,LaFemina M,Howard J,Fang X,Bhat S,Huynh KM,O'Kane CM,Ingram RJ,Muir RR,McAuley DF,Matthay MA,Sheppard D
17-0621 was used in Flow cytometry/Cell sorting to study the unexpected role for adaptive αβTh17 cells in acute respiratory distress syndrome.
Wed Jul 01 00:00:00 EDT 2015
Targeted Mutation of Nuclear Bone Morphogenetic Protein 2 Impairs Secondary Immune Response in a Mouse Model.
BioMed research international
Olsen DS,Goar WA,Nichols BA,Bailey KT,Christensen SL,Merriam KR,Reynolds PR,Wilson E,Weber KS,Bridgewater LC
Published figure using CD62L (L-Selectin) monoclonal antibody (Product # 17-0621-82) in Flow Cytometry
Mon Aug 01 00:00:00 EDT 2016
Leucocyte expression of complement C5a receptors exacerbates infarct size after myocardial reperfusion injury.
Cardiovascular research
De Hoog VC,Timmers L,Van Duijvenvoorde A,De Jager SC,Van Middelaar BJ,Smeets MB,Woodruff TM,Doevendans PA,Pasterkamp G,Hack CE,De Kleijn DP
17-0621 was used in Flow cytometry/Cell sorting to demonstrate that selective blocking of C5aR might be a promising strategy to prevent myocardial ischaemia-reperfusion injury.
Mon Sep 01 00:00:00 EDT 2014
Alphavirus-based vaccines encoding nonstructural proteins of hepatitis C virus induce robust and protective T-cell responses.
Molecular therapy : the journal of the American Society of Gene Therapy
Ip PP,Boerma A,Regts J,Meijerhof T,Wilschut J,Nijman HW,Daemen T
17-0621 was used in Flow cytometry/Cell sorting to study an rSFV-based vector which induces robust T-cell activity and has a potential for the treatment of HCV infections.
Tue Apr 01 00:00:00 EDT 2014
T Cell factor 1 represses CD8+ effector T cell formation and function.
Journal of immunology (Baltimore, Md. : 1950)
Tiemessen MM,Baert MR,Kok L,van Eggermond MC,van den Elsen PJ,Arens R,Staal FJ
17-0621 was used in Flow cytometry/Cell sorting to explore the role of the Wnt-responsive transcription factor T cell factor 1 in the initial phases of CD8(+) T effector cell formation.
Mon Dec 01 00:00:00 EST 2014
Myelin-specific T helper 17 cells promote adult hippocampal neurogenesis through indirect mechanisms.
F1000Research
Niebling J,E Rünker A,Schallenberg S,Kretschmer K,Kempermann G
17-0621 was used in Flow cytometry/Cell sorting to explore the proneurogenic potential of interleukin 17-producing T helper (Th17) cells.
Fri Mar 06 00:00:00 EST 2020
STAT4 is required for IL-23 responsiveness in Th17 memory cells and NKT cells.
JAK-STAT
Glosson-Byers NL,Sehra S,Kaplan MH
Published figure using CD62L (L-Selectin) monoclonal antibody (Product # 17-0621-82) in Flow Cytometry
Mon Sep 28 00:00:00 EDT 2015
Bhlhe40 controls cytokine production by T cells and is essential for pathogenicity in autoimmune neuroinflammation.
Nature communications
Lin CC,Bradstreet TR,Schwarzkopf EA,Sim J,Carrero JA,Chou C,Cook LE,Egawa T,Taneja R,Murphy TL,Russell JH,Edelson BT
17-0621 was used in Flow cytometry/Cell sorting to study the factors affecting pathogenicity of TH cells in experimental autoimmune encephalomyelitis (EAE), showing that Bhlhe40 controls cytokine production by T cells and is essential for pathogenicity in EAE.
Thu Apr 03 00:00:00 EDT 2014
Neoadjuvant anti-tumor vaccination prior to surgery enhances survival.
Journal of translational medicine
Fisher SA,Cleaver A,Lakhiani DD,Khong A,Connor T,Wylie B,Lesterhuis WJ,Robinson BW,Lake RA
17-0621 was used in Flow cytometry/Cell sorting to characterise changes in the proportion and activation status of immune cells associated with anti-tumour immunity.
Thu Sep 04 00:00:00 EDT 2014
Murine In vitro Memory T Cell Differentiation.
Bio-protocol
Kim MV,Ouyang W,Liao W,Zhang MQ,Li MO
17-0621 was used in Flow cytometry/Cell sorting to describe a detailed protocol for memory T cell differentiation to generate large number of CD44hiCD62Lhiantigen-specific memory T cells in vitro.
Sat Jul 05 00:00:00 EDT 2014
Vector transmission regulates immune control of Plasmodium virulence.
Nature
Spence PJ,Jarra W,Lévy P,Reid AJ,Chappell L,Brugat T,Sanders M,Berriman M,Langhorne J
17-0621 was used in Flow cytometry/Cell sorting to interrogate the regulation of parasite virulence using mosquito transmission of serially blood passaged Plasmodium chabaudi chabaudi.
Thu Jun 13 00:00:00 EDT 2013
Medullary thymic epithelial cell depletion leads to autoimmune hepatitis.
The Journal of clinical investigation
Bonito AJ,Aloman C,Fiel MI,Danzl NM,Cha S,Weinstein EG,Jeong S,Choi Y,Walsh MC,Alexandropoulos K
17-0621 was used in Flow cytometry/Cell sorting to investigate the role of TRAF6 and medullary thymic epithelial cells (mETCs) in autoimmunity, showing that mETC depletion leads to autoimmune hepatitis.
Thu Aug 01 00:00:00 EDT 2013
MHC class II-dependent B cell APC function is required for induction of CNS autoimmunity independent of myelin-specific antibodies.
The Journal of experimental medicine
Molnarfi N,Schulze-Topphoff U,Weber MS,Patarroyo JC,Prod'homme T,Varrin-Doyer M,Shetty A,Linington C,Slavin AJ,Hidalgo J,Jenne DE,Wekerle H,Sobel RA,Bernard CC,Shlomchik MJ,Zamvil SS
17-0621 was used in Flow cytometry/Cell sorting to investigate the contribution of B cells to antigen presentation and pathogenic T cell activation in the multiple sclerosis model experimental autoimmune encephalomyelitis.
Mon Dec 16 00:00:00 EST 2013
Mesenchymal stem cells are mobilized from the bone marrow during inflammation.
Frontiers in immunology
Koning JJ,Kooij G,de Vries HE,Nolte MA,Mebius RE
17-0621 was used in Flow cytometry/Cell sorting to analyse mesenchymal stem- and T-cell migration during experimental allergic encephalomyelitis.
Wed Mar 06 00:00:00 EST 2013
CD4(+) T Cell-Receptor Repertoire Diversity is Compromised in the Spleen but Not in the Bone Marrow of Aged Mice Due to Private and Sporadic Clonal Expansions.
Frontiers in immunology
Shifrut E,Baruch K,Gal H,Ndifon W,Deczkowska A,Schwartz M,Friedman N
17-0621 was used in Flow cytometry/Cell sorting to investigate the relationship between immune cell diversity and age in various tissues.
Fri Dec 06 00:00:00 EST 2013
The ubiquitin-like protein, ISG15, is a novel tumor-associated antigen for cancer immunotherapy.
Cancer immunology, immunotherapy : CII
Wood LM,Pan ZK,Seavey MM,Muthukumaran G,Paterson Y
17-0621 was used in Flow cytometry/Cell sorting to investigate ISG15, a novel tumor-associated antigen for cancer immunotherapy.
Tue May 01 00:00:00 EDT 2012
Hepatocyte-specific S100a8 and S100a9 transgene expression in mice causes Cxcl1 induction and systemic neutrophil enrichment.
Cell communication and signaling : CCS
Wiechert L,Németh J,Pusterla T,Bauer C,De Ponti A,Manthey S,Marhenke S,Vogel A,Klingmüller U,Hess J,Angel P
Published figure using CD62L (L-Selectin) monoclonal antibody (Product # 17-0621-82) in Flow Cytometry
Sat Dec 15 00:00:00 EST 2012
Anti-thymocyte globulin (ATG) differentially depletes naïve and memory T cells and permits memory-type regulatory T cells in nonobese diabetic mice.
BMC immunology
Xia CQ,Chernatynskaya AV,Wasserfall CH,Wan S,Looney BM,Eisenbeis S,Williams J,Clare-Salzler MJ,Atkinson MA
17-0621 was used in Flow cytometry/Cell sorting to assess how murine ATG therapy affects T cell subsets in NOD mice, and its influence on antigen-specific immune responses.
Fri Dec 14 00:00:00 EST 2012
A critical role for SOCS3 in innate resistance to Toxoplasma gondii.
Cell host & microbe
Whitmarsh RJ,Gray CM,Gregg B,Christian DA,May MJ,Murray PJ,Hunter CA
17-0621 was used in Flow cytometry/Cell sorting to study the role of SOCS3 in suppressing IL-6 signalling during immune responses to T. gondii infection.
Thu Sep 15 00:00:00 EDT 2011
Inferring relevant control mechanisms for interleukin-12 signaling in naïve CD4+ T cells.
Immunology and cell biology
Finley SD,Gupta D,Cheng N,Klinke DJ
17-0621 was used in Flow cytometry/Cell sorting to infer the relative importance of regulatory mechanisms that modulate the activation of STAT4 in naive CD4(+) T cells.
Sat Jan 01 00:00:00 EST 2011
A role for IL-27 in limiting T regulatory cell populations.
Journal of immunology (Baltimore, Md. : 1950)
Wojno ED,Hosken N,Stumhofer JS,O'Hara AC,Mauldin E,Fang Q,Turka LA,Levin SD,Hunter CA
17-0621 was used in Flow cytometry/Cell sorting to show that mice that overexpress IL-27 had decreased Treg frequencies and developed spontaneous inflammation.
Fri Jul 01 00:00:00 EDT 2011
Nitric oxide modulates TGF-beta-directive signals to suppress Foxp3+ regulatory T cell differentiation and potentiate Th1 development.
Journal of immunology (Baltimore, Md. : 1950)
Lee SW,Choi H,Eun SY,Fukuyama S,Croft M
17-0621 was used in Flow cytometry/Cell sorting to demonstrate that nitric oxide modulates TGF-β activity away from T cells and towards the Th1 lineage.
Wed Jun 15 00:00:00 EDT 2011
Alloreactive CD8 T-cell primed/memory responses and accelerated graft rejection in B-cell-deficient sensitized mice.
Transplantation
Ji H,Shen XD,Gao F,Busuttil RW,Zhai Y,Kupiec-Weglinski JW
17-0621 was used in Flow cytometry/Cell sorting to investigate the role of B cell deficiency in primed/memory CD8+ T cell responses and the mechanism of cardiac allograft rejection in sensitised mouse recipients.
Fri May 27 00:00:00 EDT 2011
Modeling Sjögren's syndrome with Id3 conditional knockout mice.
Immunology letters
Guo Z,Li H,Han M,Xu T,Wu X,Zhuang Y
Wed Mar 30 00:00:00 EDT 2011
Distribution of primed T cells and antigen-loaded antigen presenting cells following intranasal immunization in mice.
PloS one
Ciabattini A,Pettini E,Fiorino F,Prota G,Pozzi G,Medaglini D
17-0621 was used in Flow cytometry/Cell sorting to elucidate the trafficking of antigen-specific primed T cells to non-draining peripheral and mucosa-associated lymph nodes following nasal immunisation.
Fri Apr 29 00:00:00 EDT 2011
Experimental cerebral malaria progresses independently of the Nlrp3 inflammasome.
European journal of immunology
Reimer T,Shaw MH,Franchi L,Coban C,Ishii KJ,Akira S,Horii T,Rodriguez A,Núñez G
17-0621 was used in Flow cytometry/Cell sorting to study the role of Nlrp3 in experimental cerebral malaria.
Mon Mar 01 00:00:00 EST 2010
IL-7 promotes T cell viability, trafficking, and functionality and improves survival in sepsis.
Journal of immunology (Baltimore, Md. : 1950)
Unsinger J,McGlynn M,Kasten KR,Hoekzema AS,Watanabe E,Muenzer JT,McDonough JS,Tschoep J,Ferguson TA,McDunn JE,Morre M,Hildeman DA,Caldwell CC,Hotchkiss RS
Published figure using CD62L (L-Selectin) monoclonal antibody (Product # 17-0621-82) in Flow Cytometry
Thu Apr 01 00:00:00 EDT 2010
Peptide vaccine induces enhanced tumor growth associated with apoptosis induction in CD8+ T cells.
Journal of immunology (Baltimore, Md. : 1950)
Muraoka D,Kato T,Wang L,Maeda Y,Noguchi T,Harada N,Takeda K,Yagita H,Guillaume P,Luescher I,Old LJ,Shiku H,Nishikawa H
17-0621 was used in Flow cytometry/Cell sorting to investigate the mechanism underlying the failure of anti-tumour vaccination using synthetic peptides, showing that it induces enhanced tumour growth associated with apoptosis induction in CD8+ T cells.
Wed Sep 15 00:00:00 EDT 2010
Virulence of Toxoplasma gondii is associated with distinct dendritic cell responses and reduced numbers of activated CD8+ T cells.
Journal of immunology (Baltimore, Md. : 1950)
Tait ED,Jordan KA,Dupont CD,Harris TH,Gregg B,Wilson EH,Pepper M,Dzierszinski F,Roos DS,Hunter CA
17-0621 was used in Flow cytometry/Cell sorting to show the dendritic cell response to T.gondii alters levels of CD8+ T cells which ultimately determine the outcome of infection.
Sun Aug 01 00:00:00 EDT 2010
Conditional deletion of histone deacetylase 1 in T cells leads to enhanced airway inflammation and increased Th2 cytokine production.
Journal of immunology (Baltimore, Md. : 1950)
Grausenburger R,Bilic I,Boucheron N,Zupkovitz G,El-Housseiny L,Tschismarov R,Zhang Y,Rembold M,Gaisberger M,Hartl A,Epstein MM,Matthias P,Seiser C,Ellmeier W
17-0621 was used in Flow cytometry/Cell sorting to provide genetic evidence that HDAC1 is an essential HDAC that controls the magnitude of an inflammatory response by modulating cytokine expression in effector T cells.
Wed Sep 15 00:00:00 EDT 2010
PD-L1 regulates the development, maintenance, and function of induced regulatory T cells.
The Journal of experimental medicine
Francisco LM,Salinas VH,Brown KE,Vanguri VK,Freeman GJ,Kuchroo VK,Sharpe AH
17-0621 was used in Flow cytometry/Cell sorting to investigate the role of PD-L1 in the development and function of regulatory T cells for peripheral tolerance.
Mon Dec 21 00:00:00 EST 2009
Isolated CD39 expression on CD4+ T cells denotes both regulatory and memory populations.
American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons
Zhou Q,Yan J,Putheti P,Wu Y,Sun X,Toxavidis V,Tigges J,Kassam N,Enjyoji K,Robson SC,Strom TB,Gao W
17-0621 was used in Flow cytometry/Cell sorting to study how besides Tregs, CD39 is also expressed on pre-existing memory T cells of Th1-, Th2- and Th17-types with heightened alloreactivity.
Thu Oct 01 00:00:00 EDT 2009
Scalable analysis of flow cytometry data using R/Bioconductor.
Cytometry. Part A : the journal of the International Society for Analytical Cytology
Klinke DJ,Brundage KM
17-0621 was used in Flow cytometry/Cell sorting to demonstrate usage of a platform for the graphical and data analysis of flow cytometry data.
Sat Aug 01 00:00:00 EDT 2009
Modulation of naive CD4+ T-cell responses to an airway antigen during pulmonary mycobacterial infection.
Infection and immunity
Anis MM,Fulton SA,Reba SM,Harding CV,Boom WH
Published figure using CD62L (L-Selectin) monoclonal antibody (Product # 17-0621-82) in Flow Cytometry
Tue May 01 00:00:00 EDT 2007
TGFbeta in the context of an inflammatory cytokine milieu supports de novo differentiation of IL-17-producing T cells.
Immunity
Veldhoen M,Hocking RJ,Atkins CJ,Locksley RM,Stockinger B
17-0621 was used in Flow cytometry/Cell sorting to investigate the generation of IL-17-producing T cells from naive CD4 T cells, showing that TGFbeta supports de novo differentiation of IL-17-producing T cells.
Wed Feb 01 00:00:00 EST 2006
Spontaneous atopic dermatitis in mice expressing an inducible thymic stromal lymphopoietin transgene specifically in the skin.
The Journal of experimental medicine
Yoo J,Omori M,Gyarmati D,Zhou B,Aye T,Brewer A,Comeau MR,Campbell DJ,Ziegler SF
17-0621 was used in Flow cytometry/Cell sorting to demonstrate that TSLP can initiate a cascade of allergic inflammation in the skin of transgenic mice.
Mon Aug 15 00:00:00 EDT 2005
