Product References
Protocol for PPP1R15A-inhibited mouse model establishment with subcutaneous B16F1 tumor and single-cell analysis.
STAR protocols
Wang R,Wang M,Pei S,Zhang Y,Guo S,Guo W,Wu Z,Wang H,Li Y,Zhu Y,Meng LH,Lang J,Jin G,Xiao Y,Hu L,Kong X
Published figure using NK1.1 monoclonal antibody (Product # 45-5941-82) in Flow Cytometry
Fri Dec 15 00:00:00 EST 2023
MCL-1 Inhibitor S63845 Distinctively Affects Intramedullary and Extramedullary Hematopoiesis.
Pharmaceutics
Zhang H,Li F,Yang M,Zhang W,He M,Xu H,Wang C,Zhang Y,Wang W,Gao Y,Du X,Li Y
Published figure using NK1.1 monoclonal antibody (Product # 45-5941-82) in Flow Cytometry
Tue Mar 28 00:00:00 EDT 2023
Peripheral Neutrophils-Derived Matrix Metallopeptidase-9 Induces Postoperative Cognitive Dysfunction in Aged Mice.
Frontiers in aging neuroscience
Huang L,Tian W,Chen X,Xu H,Dai W,Zhang Y,Wu X,Yu W,Tian J,Su D
Published figure using NK1.1 monoclonal antibody (Product # 45-5941-82) in Flow Cytometry
Mon Mar 14 00:00:00 EDT 2022
NK cells require immune checkpoint receptor LILRB4/gp49B to control neurotropic Zika virus infections in mice.
JCI insight
Lee HN,Manangeeswaran M,Lewkowicz AP,Engel K,Chowdhury M,Garige M,Eckhaus MA,Sourbier C,Ireland DD,Verthelyi D
Published figure using NK1.1 monoclonal antibody (Product # 45-5941-82) in Flow Cytometry
Tue Feb 08 00:00:00 EST 2022
Valosin-containing protein (VCP/p97) inhibition reduces viral clearance and induces toxicity associated with muscular damage.
Cell death & disease
Del Rio Oliva M,Basler M
Published figure using NK1.1 monoclonal antibody (Product # 45-5941-82) in Flow Cytometry
Thu Dec 01 00:00:00 EST 2022
A novel ZsGreen knock-in melanoma cell line reveals the function of CD11b in tumor phagocytosis.
Immunology and cell biology
Zhang L,Feng X,Shen Y,Wang Y,Liu Z,Ma Y,Gu Y,Guo G,Duan L,Lu L,Liang Y,Lawrence T,Huang R
45-5941-82 was used in Flow cytometry/Cell sorting to demonstrate that the ZsGreen-expressing YUMM1.7 melanoma model provides a valuable tool for the study of phagocytosis in vivo.
Sat Oct 01 00:00:00 EDT 2022
NKT cells adopt a glutamine-addicted phenotype to regulate their homeostasis and function.
Cell reports
Kumar A,Yarosz EL,Andren A,Zhang L,Lyssiotis CA,Chang CH
45-5941-82 was used in Flow cytometry/Cell sorting to highlight a distinct metabolic requirement of NKT cells compared with CD4 T cells, which may have therapeutic implications in the treatment of certain nutrient-restricted diseases.
Tue Oct 25 00:00:00 EDT 2022
Cytotoxic lymphocytes target characteristic biophysical vulnerabilities in cancer.
Immunity
Tello-Lafoz M,Srpan K,Sanchez EE,Hu J,Remsik J,Romin Y,Calò A,Hoen D,Bhanot U,Morris L,Boire A,Hsu KC,Massagué J,Huse M,Er EE
45-5941-82 was used in Flow cytometry/Cell sorting to suggest that immunosurveillance has a mechanical dimension, which we call mechanosurveillance, that is particularly relevant for the targeting of metastatic disease.
Tue May 11 00:00:00 EDT 2021
The transcriptional repressor ID2 supports natural killer cell maturation by controlling TCF1 amplitude.
The Journal of experimental medicine
Li ZY,Morman RE,Hegermiller E,Sun M,Bartom ET,Maienschein-Cline M,Sigvardsson M,Kee BL
Published figure using NK1.1 monoclonal antibody (Product # 45-5941-82) in Flow Cytometry
Mon Jun 07 00:00:00 EDT 2021
Chronic T cell proliferation in brains after stroke could interfere with the efficacy of immunotherapies.
The Journal of experimental medicine
Heindl S,Ricci A,Carofiglio O,Zhou Q,Arzberger T,Lenart N,Franzmeier N,Hortobagyi T,Nelson PT,Stowe AM,Denes A,Edbauer D,Liesz A
Published figure using NK1.1 monoclonal antibody (Product # 45-5941-82) in Flow Cytometry
Mon Aug 02 00:00:00 EDT 2021
Exosomal lncRNA SNHG10 derived from colorectal cancer cells suppresses natural killer cell cytotoxicity by upregulating INHBC.
Cancer cell international
Huang Y,Luo Y,Ou W,Wang Y,Dong D,Peng X,Luo Y
Published figure using NK1.1 monoclonal antibody (Product # 45-5941-82) in Flow Cytometry
Tue Oct 12 00:00:00 EDT 2021
Expression of CCRL2 Inhibits Tumor Growth by Concentrating Chemerin and Inhibiting Neoangiogenesis.
Cancers
Al Delbany D,Robert V,Dubois-Vedrenne I,Del Prete A,Vernimmen M,Radi A,Lefort A,Libert F,Wittamer V,Sozzani S,Parmentier M
Published figure using NK1.1 monoclonal antibody (Product # 45-5941-82) in Flow Cytometry
Tue Oct 05 00:00:00 EDT 2021
Near-infrared photoimmunotherapy targeting human-EGFR in a mouse tumor model simulating current and future clinical trials.
EBioMedicine
Okada R,Furusawa A,Vermeer DW,Inagaki F,Wakiyama H,Kato T,Nagaya T,Choyke PL,Spanos WC,Allen CT,Kobayashi H
45-5941-82 was used in Flow Cytometry to conclude that combined hEGFR and CD25-targeted NIR-PIT is a promising treatment for hEGFR expressing cancers in which Treg cells play an immunosuppressive role.
Sat May 01 00:00:00 EDT 2021
Near-infrared photoimmunotherapy targeting human-EGFR in a mouse tumor model simulating current and future clinical trials.
EBioMedicine
Okada R,Furusawa A,Vermeer DW,Inagaki F,Wakiyama H,Kato T,Nagaya T,Choyke PL,Spanos WC,Allen CT,Kobayashi H
45-5941-82 was used in Flow Cytometry to conclude that combined hEGFR and CD25-targeted NIR-PIT is a promising treatment for hEGFR expressing cancers in which Treg cells play an immunosuppressive role.
Sat May 01 00:00:00 EDT 2021
A novel miR1983-TLR7-IFNβ circuit licenses NK cells to kill glioma cells, and is under the control of galectin-1.
Oncoimmunology
Shah D,Comba A,Faisal SM,Kadiyala P,Baker GJ,Alghamri MS,Doherty R,Zamler D,Nuñez G,Castro MG,Lowenstein PR
Published figure using NK1.1 monoclonal antibody (Product # 45-5941-82) in Flow Cytometry
Mon Aug 02 00:00:00 EDT 2021
Association between cellular immune response and spleen weight in mice with hepatocellular carcinoma.
Oncology letters
Jiang W,Li Y,Zhang S,Kong G,Li Z
45-5941-82 was used in flow cytometry to present study revealed a novel role for the spleen in predicting the cellular immune response in tumor-bearing mice.
Sun Aug 01 00:00:00 EDT 2021
Sequencing, cloning, and antigen binding analysis of monoclonal antibodies isolated from single mouse B cells.
STAR protocols
Viant C,Escolano A,Chen ST,Nussenzweig MC
Published figure using NK1.1 monoclonal antibody (Product # 45-5941-82) in Flow Cytometry
Fri Jun 18 00:00:00 EDT 2021
The enrichment of neutrophil extracellular traps impair the placentas of systemic lupus erythematosus through accumulating decidual NK cells.
Scientific reports
Jiang M,Shen N,Zhou H,Wang Y,Lin S,Wu J,Di W
45-5941-82 was used in Flow Cytometry to show that NETs may contribute to immunological disorder in the placenta and the pathological changes in pregnancies with SLE, which provides a research basis for further explorations of the mechanism of SLE in placental impairment.
Thu Mar 25 00:00:00 EDT 2021
The enrichment of neutrophil extracellular traps impair the placentas of systemic lupus erythematosus through accumulating decidual NK cells.
Scientific reports
Jiang M,Shen N,Zhou H,Wang Y,Lin S,Wu J,Di W
45-5941-82 was used in Flow Cytometry to show that NETs may contribute to immunological disorder in the placenta and the pathological changes in pregnancies with SLE, which provides a research basis for further explorations of the mechanism of SLE in placental impairment.
Thu Mar 25 00:00:00 EDT 2021
Serum Amyloid A Proteins Induce Pathogenic Th17 Cells and Promote Inflammatory Disease.
Cell
Lee JY,Hall JA,Kroehling L,Wu L,Najar T,Nguyen HH,Lin WY,Yeung ST,Silva HM,Li D,Hine A,Loke P,Hudesman D,Martin JC,Kenigsberg E,Merad M,Khanna KM,Littman DR
45-5941 was used in Flow cytometry/Cell sorting to suggest that serum amyloid A proteins direct a pathogenic pro-inflammatory Th17 cell differentiation program and promote Th17-mediated inflammatory diseases.
Thu Jan 09 00:00:00 EST 2020
Legionella-Infected Macrophages Engage the Alveolar Epithelium to Metabolically Reprogram Myeloid Cells and Promote Antibacterial Inflammation.
Cell host & microbe
Liu X,Boyer MA,Holmgren AM,Shin S
45-5941-82 was used in Flow Cytometry to reveal that alveolar macrophages engage alveolar epithelial signals to metabolically reprogram monocytes for antibacterial inflammation.
Wed Nov 11 00:00:00 EST 2020
Patrolling Monocytes Control NK Cell Expression of Activating and Stimulatory Receptors to Curtail Lung Metastases.
Journal of immunology (Baltimore, Md. : 1950)
Narasimhan PB,Eggert T,Zhu YP,Marcovecchio P,Meyer MA,Wu R,Hedrick CC
45-5941-82 was used in Flow Cytometry to investigate the role of nonclassical, patrolling monocytes in lung tumor metastasis and their functional relationships with other immune cells.
Wed Jan 01 00:00:00 EST 2020
Control of Viral Infection by Natural Killer Cell Inhibitory Receptors.
Cell reports
Parikh BA,Bern MD,Piersma SJ,Yang L,Beckman DL,Poursine-Laurent J,Plougastel-Douglas B,Yokoyama WM
45-5941 was used in Flow cytometry/Cell sorting to show MHC-I-restricted control of murine cytomegalovirus (MCMV) infection in vivo that is NK cell dependent.
Tue Jul 28 00:00:00 EDT 2020
Analysis of Myeloid Cells in Mouse Tissues with Flow Cytometry.
STAR protocols
Liu Z,Gu Y,Shin A,Zhang S,Ginhoux F
Published figure using NK1.1 monoclonal antibody (Product # 45-5941-82) in Flow Cytometry
Fri Jun 19 00:00:00 EDT 2020
Acid ceramidase of macrophages traps herpes simplex virus in multivesicular bodies and protects from severe disease.
Nature communications
Lang J,Bohn P,Bhat H,Jastrow H,Walkenfort B,Cansiz F,Fink J,Bauer M,Olszewski D,Ramos-Nascimento A,Duhan V,Friedrich SK,Becker KA,Krawczyk A,Edwards MJ,Burchert A,Huber M,Friebus-Kardash J,Göthert JR,Hardt C,Probst HC,Schumacher F,Köhrer K,Kleuser B,Babiychuk EB,Sodeik B,Seibel J,Greber UF,Lang PA,Gulbins E,Lang KS
45-5941-82 was used in Flow Cytometry to show that macrophages take up HSV-1 via endocytosis and transport the virions into multivesicular bodies (MVBs).
Thu Mar 12 00:00:00 EDT 2020
Dendritic Cells and Myeloid Derived Suppressor Cells Fully Responsive to Stimulation via Toll-Like Receptor 4 Are Rapidly Induced from Bone-Marrow Cells by Granulocyte-Macrophage Colony-Stimulating Factor.
Vaccines
Kong YY,Wilson K,Apostolopoulos V,Plebanski M
Published figure using NK1.1 monoclonal antibody (Product # 45-5941-82) in Flow Cytometry
Sat Sep 12 00:00:00 EDT 2020
Immunization expands B cells specific to HIV-1 V3 glycan in mice and macaques.
Nature
Escolano A,Gristick HB,Abernathy ME,Merkenschlager J,Gautam R,Oliveira TY,Pai J,West AP,Barnes CO,Cohen AA,Wang H,Golijanin J,Yost D,Keeffe JR,Wang Z,Zhao P,Yao KH,Bauer J,Nogueira L,Gao H,Voll AV,Montefiori DC,Seaman MS,Gazumyan A,Silva M,McGuire AT,Stamatatos L,Irvine DJ,Wells L,Martin MA,Bjorkman PJ,Nussenzweig MC
Published figure using NK1.1 monoclonal antibody (Product # 45-5941-82) in Flow Cytometry
Sat Jun 01 00:00:00 EDT 2019
Deletion of C-C Motif Chemokine Ligand 5 Worsens Invariant Natural Killer T-Cell-Mediated Hepatitis via Compensatory Up-regulation of CXCR2-Related Chemokine Activity.
Cellular and molecular gastroenterology and hepatology
Chen L,Gu J,Qian Y,Li M,Qian Y,Xu M,Li J,Wen Y,Xia L,Li J,Xia Q,Kong X,Wu H
Published figure using NK1.1 monoclonal antibody (Product # 45-5941-82) in Flow Cytometry
Tue Jun 04 00:00:00 EDT 2019
Synergized regulation of NK cell education by NKG2A and specific Ly49 family members.
Nature communications
Zhang X,Feng J,Chen S,Yang H,Dong Z
Published figure using NK1.1 monoclonal antibody (Product # 45-5941-82) in Flow Cytometry
Fri Nov 01 00:00:00 EDT 2019
Progranulin prevents regulatory NK cell cytotoxicity against antiviral T cells.
JCI insight
Huang A,Shinde PV,Huang J,Senff T,Xu HC,Margotta C,Häussinger D,Willnow TE,Zhang J,Pandyra AA,Timm J,Weggen S,Lang KS,Lang PA
Published figure using NK1.1 monoclonal antibody (Product # 45-5941-82) in Flow Cytometry
Thu Sep 05 00:00:00 EDT 2019
Antitumor immunity augments the therapeutic effects of p53 activation on acute myeloid leukemia.
Nature communications
Hayashi Y,Goyama S,Liu X,Tamura M,Asada S,Tanaka Y,Fukuyama T,Wunderlich M,O'Brien E,Mizukawa B,Yamazaki S,Matsumoto A,Yamasaki S,Shibata T,Matsuda K,Sashida G,Takizawa H,Kitamura T
Published figure using NK1.1 monoclonal antibody (Product # 45-5941-82) in Flow Cytometry
Fri Oct 25 00:00:00 EDT 2019
Keap1-Nrf2 System Plays an Important Role in Invariant Natural Killer T Cell Development and Homeostasis.
Cell reports
Pyaram K,Kumar A,Kim YH,Noel S,Reddy SP,Rabb H,Chang CH
45-5941 was used in Flow cytometry/Cell sorting to report that T cellspecific deletion of Keap1 results in defective development and reduced numbers of invariant natural killer T (NKT) cells in the thymus and the peripheral organs in a cell-intrinsic manner.
Tue Apr 16 00:00:00 EDT 2019
Invariant natural killer T-cell development and function with loss of microRNA-155.
Immunology
Frias AB,Buechel HM,Neupane A,D'Cruz LM
45-5941 was used in Flow cytometry/Cell sorting to examine the role of microRNA-155 in the development and function of invariant natural killer T cells.
Thu Feb 01 00:00:00 EST 2018
CD8+ T cells mediate the antitumor activity of frankincense and myrrh in hepatocellular carcinoma.
Journal of translational medicine
Xu C,Lu X,Liu W,Chen A,Meng G,Zhang H,Li B,Zhang Y,Wu J,Wei J
Published figure using NK1.1 monoclonal antibody (Product # 45-5941-82) in Flow Cytometry
Mon May 21 00:00:00 EDT 2018
Plasmodium co-infection protects against chikungunya virus-induced pathologies.
Nature communications
Teo TH,Lum FM,Ghaffar K,Chan YH,Amrun SN,Tan JJL,Lee CYP,Chua TK,Carissimo G,Lee WWL,Claser C,Rajarethinam R,Rénia L,Ng LFP
Published figure using NK1.1 monoclonal antibody (Product # 45-5941-82) in Flow Cytometry
Tue Sep 25 00:00:00 EDT 2018
CD24-p53 axis suppresses diethylnitrosamine-induced hepatocellular carcinogenesis by sustaining intrahepatic macrophages.
Cell discovery
Li D,Hu M,Liu Y,Ye P,Du P,Li CS,Cheng L,Liu P,Jiang J,Su L,Wang S,Zheng P,Liu Y
45-5941-82 was used in Flow cytometry/Cell sorting to show that targeted mutation of Cd24 dramatically increased HCC burden while reducing intrahepatic macrophages and DEN-induced hepatocyte apoptosis.
Thu Oct 01 00:00:00 EDT 2020
Differentiation of human and murine induced pluripotent stem cells to microglia-like cells.
Nature neuroscience
Pandya H,Shen MJ,Ichikawa DM,Sedlock AB,Choi Y,Johnson KR,Kim G,Brown MA,Elkahloun AG,Maric D,Sweeney CL,Gossa S,Malech HL,McGavern DB,Park JK
Published figure using NK1.1 monoclonal antibody (Product # 45-5941-82) in Flow Cytometry
Mon May 01 00:00:00 EDT 2017
A TLR7 agonist enhances the antitumor efficacy of obinutuzumab in murine lymphoma models via NK cells and CD4 T cells.
Leukemia
Cheadle EJ,Lipowska-Bhalla G,Dovedi SJ,Fagnano E,Klein C,Honeychurch J,Illidge TM
Published figure using NK1.1 monoclonal antibody (Product # 45-5941-82) in Flow Cytometry
Sat Jul 01 00:00:00 EDT 2017
Different Lymphocyte Populations Direct Dichotomous Eosinophil or Neutrophil Responses to Pulmonary Cryptococcus Infection.
Journal of immunology (Baltimore, Md. : 1950)
Wiesner DL,Smith KD,Kashem SW,Bohjanen PR,Nielsen K
45-5941 was used in Flow cytometry/Cell sorting to study the lymphocyte subsets responsible for the oesinophil or neutrophil response to infection with Cryptococcus neoformans.
Wed Feb 15 00:00:00 EST 2017
IL-2/Anti-IL-2 Complex Attenuates Inflammation and BBB Disruption in Mice Subjected to Traumatic Brain Injury.
Frontiers in neurology
Gao W,Li F,Zhou Z,Xu X,Wu Y,Zhou S,Yin D,Sun D,Xiong J,Jiang R,Zhang J
Published figure using NK1.1 monoclonal antibody (Product # 45-5941-82) in Flow Cytometry
Thu Oct 01 00:00:00 EDT 2020
Loss of HIF-1α in natural killer cells inhibits tumour growth by stimulating non-productive angiogenesis.
Nature communications
Krzywinska E,Kantari-Mimoun C,Kerdiles Y,Sobecki M,Isagawa T,Gotthardt D,Castells M,Haubold J,Millien C,Viel T,Tavitian B,Takeda N,Fandrey J,Vivier E,Sexl V,Stockmann C
Published figure using NK1.1 monoclonal antibody (Product # 45-5941-82) in Flow Cytometry
Fri Nov 17 00:00:00 EST 2017
Differential regulation of C5a receptor 1 in innate immune cells during the allergic asthma effector phase.
PloS one
Ender F,Wiese AV,Schmudde I,Sun J,Vollbrandt T,König P,Laumonnier Y,Köhl J
45-5941 was used in Flow cytometry/Cell sorting to demonstrate a complex regulation pattern of C5aR1 in the airways, lung tissue and lymph nodes of mice.
Thu Aug 17 00:00:00 EDT 2017
Single-cell tracking of flavivirus RNA uncovers species-specific interactions with the immune system dictating disease outcome.
Nature communications
Douam F,Hrebikova G,Albrecht YE,Sellau J,Sharon Y,Ding Q,Ploss A
45-5941 was used in Flow cytometry/Cell sorting to demonstrate the tracking of and sense viral RNA at single-cell resolution within complex subsets of the human and murine immune system in different mouse models.
Tue Mar 14 00:00:00 EDT 2017
Type III Interferon-Mediated Signaling Is Critical for Controlling Live Attenuated Yellow Fever Virus Infection In Vivo.
mBio
Douam F,Soto Albrecht YE,Hrebikova G,Sadimin E,Davidson C,Kotenko SV,Ploss A
45-5941 was used in Flow cytometry/Cell sorting to analyse the role of type III interferon (IFN)-mediated signaling in controlling the infection and attenuation of the live attenuated yellow virus strain, YFV-17D.
Tue Aug 15 00:00:00 EDT 2017
Macrophage autophagy limits acute toxic liver injury in mice through down regulation of interleukin-1β.
Journal of hepatology
Ilyas G,Zhao E,Liu K,Lin Y,Tesfa L,Tanaka KE,Czaja MJ
45-5941 was used in Flow cytometry/Cell sorting to show that macrophage autophagy functions to limit acute toxin-induced liver injury and death by inhibiting the generation of inflammasome-dependent IL-1β.
Fri Jan 01 00:00:00 EST 2016
The breast tumor microenvironment alters the phenotype and function of natural killer cells.
Cellular & molecular immunology
Krneta T,Gillgrass A,Chew M,Ashkar AA
Published figure using NK1.1 monoclonal antibody (Product # 45-5941-82) in Flow Cytometry
Thu Sep 01 00:00:00 EDT 2016
Resolving TYK2 locus genotype-to-phenotype differences in autoimmunity.
Science translational medicine
Dendrou CA,Cortes A,Shipman L,Evans HG,Attfield KE,Jostins L,Barber T,Kaur G,Kuttikkatte SB,Leach OA,Desel C,Faergeman SL,Cheeseman J,Neville MJ,Sawcer S,Compston A,Johnson AR,Everett C,Bell JI,Karpe F,Ultsch M,Eigenbrot C,McVean G,Fugger L
45-5941 was used in Flow cytometry/Cell sorting to reveal a protective homozygous effect that defined a signalling optimum between autoimmunity and immunodeficiency and identified TYK2 as a potential drug target for autoimmune disorders.
Wed Nov 02 00:00:00 EDT 2016
NKT sublineage specification and survival requires the ubiquitin-modifying enzyme TNFAIP3/A20.
The Journal of experimental medicine
Drennan MB,Govindarajan S,Verheugen E,Coquet JM,Staal J,McGuire C,Taghon T,Leclercq G,Beyaert R,van Loo G,Lambrecht BN,Elewaut D
45-5941 was used in Flow cytometry/Cell sorting to show that negative regulation of TCR signalling during NKT development controls the differentiation and survival of NKT1 and NKT2 cells.
Mon Sep 19 00:00:00 EDT 2016
Hypoxia-Inducible Factor-2α Limits Natural Killer T Cell Cytotoxicity in Renal Ischemia/Reperfusion Injury.
Journal of the American Society of Nephrology : JASN
Zhang J,Han C,Dai H,Hou J,Dong Y,Cui X,Xu L,Zhang M,Xia Q
Published figure using NK1.1 monoclonal antibody (Product # 45-5941-82) in Flow Cytometry
Fri Jan 01 00:00:00 EST 2016
IL-33-Dependent Group 2 Innate Lymphoid Cells Promote Cutaneous Wound Healing.
The Journal of investigative dermatology
Rak GD,Osborne LC,Siracusa MC,Kim BS,Wang K,Bayat A,Artis D,Volk SW
45-5941 was used in Flow cytometry/Cell sorting to demonstrate that cutaneous injury promotes an IL-33-dependent group 2 ILC response and that abrogation of this response can impair efficient wound closure.
Mon Feb 01 00:00:00 EST 2016
Id2 regulates hyporesponsive invariant natural killer T cells.
Immunology and cell biology
Stradner MH,Cheung KP,Lasorella A,Goldrath AW,D'Cruz LM
45-5941 was used in Flow cytometry/Cell sorting to propose that downregulation of Id2 expression is essential to induction of the anti-inflammatory state in iNKT cells.
Mon Aug 01 00:00:00 EDT 2016
NK cell development requires Tsc1-dependent negative regulation of IL-15-triggered mTORC1 activation.
Nature communications
Yang M,Chen S,Du J,He J,Wang Y,Li Z,Liu G,Peng W,Zeng X,Li D,Xu P,Guo W,Chang Z,Wang S,Tian Z,Dong Z
Published figure using NK1.1 monoclonal antibody (Product # 45-5941-82) in Flow Cytometry
Wed Sep 07 00:00:00 EDT 2016
CXCL16-positive dendritic cells enhance invariant natural killer T cell-dependent IFNγ production and tumor control.
Oncoimmunology
Veinotte L,Gebremeskel S,Johnston B
45-5941 was used in Flow cytometry/Cell sorting to study the co-stimulatory role of CXCR6/CXCL16 interactions in glycolipid-dependent invariant natural killer T (iNKT) cell activation and tumour control, showing that CXCL16-positive dendritic cells enhance iNKT cell-dependent IFNγ production and tumor control.
Wed Jun 01 00:00:00 EDT 2016
A small-molecule inhibitor of SHIP1 reverses age- and diet-associated obesity and metabolic syndrome.
JCI insight
Srivastava N,Iyer S,Sudan R,Youngs C,Engelman RW,Howard KT,Russo CM,Chisholm JD,Kerr WG
45-5941 was used in Flow cytometry/Cell sorting to investigate how SHIPi represents an approach that permits control of obesity and diet-induced metabolic syndrome without apparent toxicity.
Thu Jul 21 00:00:00 EDT 2016
Group 2 innate lymphoid cells promote beiging of white adipose tissue and limit obesity.
Nature
Brestoff JR,Kim BS,Saenz SA,Stine RR,Monticelli LA,Sonnenberg GF,Thome JJ,Farber DL,Lutfy K,Seale P,Artis D
45-5941 was used in Flow cytometry/Cell sorting to study how ILC2s can regulate adipose function and metabolic homeostasis.
Thu Mar 12 00:00:00 EDT 2015
The Inflammatory Caspases-1 and -11 Mediate the Pathogenesis of Dermatitis in Sharpin-Deficient Mice.
Journal of immunology (Baltimore, Md. : 1950)
Douglas T,Champagne C,Morizot A,Lapointe JM,Saleh M
45-5941 was used in Flow cytometry/Cell sorting to implicate the inflammasome as an important initiating signal in skin disease pathogenesis.
Tue Sep 01 00:00:00 EDT 2015
Favorable alteration of tumor microenvironment by immunomodulatory cytokines for efficient T-cell therapy in solid tumors.
PloS one
Tähtinen S,Kaikkonen S,Merisalo-Soikkeli M,Grönberg-Vähä-Koskela S,Kanerva A,Parviainen S,Vähä-Koskela M,Hemminki A
Published figure using NK1.1 monoclonal antibody (Product # 45-5941-82) in Flow Cytometry
Thu Apr 28 00:00:00 EDT 2016
Metronomic cyclophosphamide eradicates large implanted GL261 gliomas by activating antitumor Cd8+ T-cell responses and immune memory.
Oncoimmunology
Wu J,Waxman DJ
Published figure using NK1.1 monoclonal antibody (Product # 45-5941-82) in Flow Cytometry
Wed Apr 01 00:00:00 EDT 2015
The cholesterol transporter ABCG1 links cholesterol homeostasis and tumour immunity.
Nature communications
Sag D,Cekic C,Wu R,Linden J,Hedrick CC
45-5941 was used in Flow cytometry/Cell sorting to demonstrate that the absence of ABCG1 inhibits tumour growth through modulation of macrophage function within the tumour.
Fri Feb 27 00:00:00 EST 2015
Anti-G-CSF treatment induces protective tumor immunity in mouse colon cancer by promoting protective NK cell, macrophage and T cell responses.
Oncotarget
Morris KT,Castillo EF,Ray AL,Weston LL,Nofchissey RA,Hanson JA,Samedi VG,Pinchuk IV,Hudson LG,Beswick EJ
45-5941 was used in Flow cytometry/Cell sorting to indicate a crucial role for G-CSF inhibition in promoting protective anti-tumor immunity.
Tue Sep 08 00:00:00 EDT 2015
E and Id proteins influence invariant NKT cell sublineage differentiation and proliferation.
Journal of immunology (Baltimore, Md. : 1950)
D'Cruz LM,Stradner MH,Yang CY,Goldrath AW
45-5941 was used in Flow cytometry/Cell sorting to investigate the mechanism by which E and Id proteins control the development of invariant NKT sublineages after positive selection.
Sat Mar 01 00:00:00 EST 2014
Leukocyte population dynamics and detection of IL-9 as a major cytokine at the mouse fetal-maternal interface.
PloS one
Habbeddine M,Verbeke P,Karaz S,Bobé P,Kanellopoulos-Langevin C
Published figure using NK1.1 monoclonal antibody (Product # 45-5941-82) in Flow Cytometry
Wed Jun 10 00:00:00 EDT 2015
mRNA-based vaccines synergize with radiation therapy to eradicate established tumors.
Radiation oncology (London, England)
Fotin-Mleczek M,Zanzinger K,Heidenreich R,Lorenz C,Kowalczyk A,Kallen KJ,Huber SM
45-5941 was used in Flow cytometry/Cell sorting to investigate how mRNA-based vaccines interact with radiation therapy in treating established tumours.
Fri Aug 15 00:00:00 EDT 2014
CD22 is required for protection against West Nile virus Infection.
Journal of virology
Ma DY,Suthar MS,Kasahara S,Gale M,Clark EA
45-5941 was used in Flow cytometry/Cell sorting to elucidate the immunological requirements for an antibody response following West Nile virus infection.
Fri Mar 01 00:00:00 EST 2013
Markers of nonselective and specific NK cell activation.
Journal of immunology (Baltimore, Md. : 1950)
Fogel LA,Sun MM,Geurs TL,Carayannopoulos LN,French AR
45-5941 was used in Flow cytometry/Cell sorting to demonstrate that a combination of Sca-1, CD27, and KLRG1 can distinguish NK cells based on their mechanism of activation.
Sat Jun 15 00:00:00 EDT 2013
VEGF receptor inhibitors block the ability of metronomically dosed cyclophosphamide to activate innate immunity-induced tumor regression.
Cancer research
Doloff JC,Waxman DJ
Published figure using NK1.1 monoclonal antibody (Product # 45-5941-82) in Flow Cytometry
Thu Mar 01 00:00:00 EST 2012
Highly potent mRNA based cancer vaccines represent an attractive platform for combination therapies supporting an improved therapeutic effect.
The journal of gene medicine
Fotin-Mleczek M,Zanzinger K,Heidenreich R,Lorenz C,Thess A,Duchardt KM,Kallen KJ
45-5941 was used in Flow cytometry/Cell sorting to study the effects of CureVac's mRNA vaccines in prostate cancer and non-small cell lung carcinoma patients.
Fri Jun 01 00:00:00 EDT 2012
Innate lymphoid cells promote lung-tissue homeostasis after infection with influenza virus.
Nature immunology
Monticelli LA,Sonnenberg GF,Abt MC,Alenghat T,Ziegler CG,Doering TA,Angelosanto JM,Laidlaw BJ,Yang CY,Sathaliyawala T,Kubota M,Turner D,Diamond JM,Goldrath AW,Farber DL,Collman RG,Wherry EJ,Artis D
45-5941 was used in Flow cytometry/Cell sorting to demonstrate a critical role for lung ILCs in restoring airway epithelial integrity and tissue homeostasis after viral replication.
Tue Nov 01 00:00:00 EDT 2011
IL-17-producing invariant NKT cells in lymphoid organs are recent thymic emigrants identified by neuropilin-1 expression.
Blood
Milpied P,Massot B,Renand A,Diem S,Herbelin A,Leite-de-Moraes M,Rubio MT,Hermine O
45-5941 was used in Flow cytometry/Cell sorting to determine the function of recent thymic emigrant invariant natural killer (RTE TiNKT) cells in naive mice.
Thu Sep 15 00:00:00 EDT 2011
TCR-dependent and -independent activation underlie liver-specific regulation of NKT cells.
Journal of immunology (Baltimore, Md. : 1950)
Subleski JJ,Hall VL,Wolfe TB,Scarzello AJ,Weiss JM,Chan T,Hodge DL,Back TC,Ortaldo JR,Wiltrout RH
45-5941 was used in Flow cytometry/Cell sorting to investigate TCR -dependent and -independent activation of NKT cells in the liver.
Sat Jan 15 00:00:00 EST 2011
Interleukin-22 (IL-22) production by pulmonary Natural Killer cells and the potential role of IL-22 during primary influenza virus infection.
Journal of virology
Guo H,Topham DJ
45-5941 was used in Flow cytometry/Cell sorting to test whether interleukin-22 (IL-22) is protective during influenza virus infection, showing that IL-22 plays a marginal role for protection, with a differential requirement of this cytokine for bacterial and viral infections.
Sun Aug 01 00:00:00 EDT 2010
Influenza infection leads to increased susceptibility to subsequent bacterial superinfection by impairing NK cell responses in the lung.
Journal of immunology (Baltimore, Md. : 1950)
Small CL,Shaler CR,McCormick S,Jeyanathan M,Damjanovic D,Brown EG,Arck P,Jordana M,Kaushic C,Ashkar AA,Xing Z
45-5941 was used in Flow cytometry/Cell sorting to identify weakened NK cell response in the lung to be a critical mechanism for flu-mediated susceptibility to bacterial superinfection.
Mon Feb 15 00:00:00 EST 2010
