Invitrogen

NK1.1 Monoclonal Antibody (PK136), Alexa Fluor™ 700, eBioscience™

54 Published Figures

48 References

View all (46) NK1.1 antibodies

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Protocols

Questions & Answers

Datasheet

Protocols

Questions & Answers

Antibody Testing Data (1)
Published Figures (54)

FIGURE: 1 / 55

NK1.1 Antibody (56-5941-82) in Flow

Staining of C57Bl/6 splenocytes with Anti-Mouse CD49b (Integrin alpha 2) APC (Product # 17-5971-82) and 0.5 µg of Rat IgG2a K Isotype Control Alexa Fluor® 700 (Product # 56-4321-80) (left) or 0.5 µg of Anti-Mouse NK1-1 Alexa Fluor® 700 (right). Cells in the lymphocyte gate were used for analysis.

NK1.1 Antibody in Immunohistochemistry (IHC)

Product Image Gallery

Product Details

56-5941-82

Applications

Tested Dilution

Publications

Immunohistochemistry (IHC)

View 2 publications 2 publications

Flow Cytometry (Flow)

1 µg/test

View 45 publications 45 publications

Miscellaneous PubMed (Misc)

View 1 publication 1 publication

Product Specifications

Species Reactivity

Mouse

Published species

Human, Mouse

Host/Isotype

Mouse / IgG2a, kappa

Recommended Isotype Control

Mouse IgG2a kappa Isotype Control (eBM2a), Alexa Fluor™ 700, eBioscience™

Class

Monoclonal

Type

Antibody

Clone

PK136

Conjugate

Alexa Fluor™ 700 Alexa Fluor™ 700 Alexa Fluor™ 700

Excitation/Emission Max

696/719 nm View spectra

Form

Liquid

Concentration

0.2 mg/mL

Purification

Affinity chromatography

Storage buffer

PBS, pH 7.2

Contains

0.09% sodium azide

Storage conditions

4° C, store in dark, DO NOT FREEZE!

Shipping conditions

Ambient (domestic); Wet ice (international)

RRID

AB_2574505

Product Specific Information

Description: The PK136 monoclonal antibody reacts with mouse NK1.1, an antigen expressed by natural killer cells and a subset of T cells in the NK1.1 mouse strains including C57BL and NZB. Several commonly used laboratory mouse strains such as BALB/c, SJL, AKR, CBA, C3H and A do not express the NK1.1 antigen. For detection of NK cells in these strains the monoclonal antibody DX5 (Product # 14-5971) should be used. Simultaneous staining of C57BL/6 spleen cells with PK136 and DX5 reveals coexpression of both markers by a majority of cells as well as presence of small populations of DX5+PK136- and DX5-PK136+ cells.

Applications Reported: This PK136 antibody has been reported for use in flow cytometric analysis.

Applications Tested: This PK136 antibody has been tested by flow cytometric analysis of mouse splenocytes. This can be used at less than or equal to 1 µg per test. A test is defined as the amount (µg) of antibody that will stain a cell sample in a final volume of 100 µL. Cell number should be determined empirically but can range from 10^5 to 10^8 cells/test. It is recommended that the antibody be carefully titrated for optimal performance in the assay of interest.

Alexa Fluor® 700 emits at 723 nm and can be excited with the red laser (633 nm). Most instruments will require a 685 LP mirror and 710/20 filter. Please make sure that your instrument is capable of detecting this fluorochrome.

Excitation: 633-647 nm; Emission: 723 nm; Laser: Red Laser.

Filtration: 0.2 µm post-manufacturing filtered.

Target Information

NK1.1 (Killer cell lectin-like receptor subfamily B, member 1, KLRB1, NKR-P1A, CD161, cluster of differentiation 161), refers to Natural Killer (NK) cells, lymphocytes that mediate cytotoxicity and secrete cytokines after immune stimulation. Several genes of the C-type lectin superfamily, including the rodent NKRP1 family of glycoproteins, are expressed by NK cells and may be involved in the regulation of NK cell function. The KLRB1 protein contains an extracellular domain with several motifs characteristic of C-type lectins, a transmembrane domain, and a cytoplasmic domain. The KLRB1 protein, NKR-P1A or CD161, is classified as a type II membrane protein because it has an external C terminus. NKR-P1A, the receptor encoded by the KLRB1 gene, recognizes Lectin Like Transcript-1 (LLT1) as a functional ligand.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

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Product References

A combination of genetically engineered oncolytic virus and melittin-CpG for cancer viro-chemo-immunotherapy.

BMC medicine

Bahreyni A,Liu H,Mohamud Y,Xue YC,Fan YM,Zhang YL,Luo H

Published figure using NK1.1 monoclonal antibody (Product # 56-5941-82) in Immunohistochemistry

Wed May 24 00:00:00 EDT 2023

Protocol for PPP1R15A-inhibited mouse model establishment with subcutaneous B16F1 tumor and single-cell analysis.

STAR protocols

Wang R,Wang M,Pei S,Zhang Y,Guo S,Guo W,Wu Z,Wang H,Li Y,Zhu Y,Meng LH,Lang J,Jin G,Xiao Y,Hu L,Kong X

Published figure using NK1.1 monoclonal antibody (Product # 56-5941-82) in Flow Cytometry

Fri Dec 15 00:00:00 EST 2023

MCL-1 Inhibitor S63845 Distinctively Affects Intramedullary and Extramedullary Hematopoiesis.

Pharmaceutics

Zhang H,Li F,Yang M,Zhang W,He M,Xu H,Wang C,Zhang Y,Wang W,Gao Y,Du X,Li Y

Published figure using NK1.1 monoclonal antibody (Product # 56-5941-82) in Flow Cytometry

Tue Mar 28 00:00:00 EDT 2023

Toll-like receptor mediated inflammation directs B cells towards protective antiviral extrafollicular responses.

Nature communications

Lam JH,Baumgarth N

56-5941-82 was used in Flow cytometry/Cell sorting to show that influenza infection rapidly induces EFRs, generating protective antibodies via Toll-like receptor (TLR)-mediated mechanisms that are both B cell intrinsic and extrinsic.

Wed Jul 05 00:00:00 EDT 2023

Peripheral Neutrophils-Derived Matrix Metallopeptidase-9 Induces Postoperative Cognitive Dysfunction in Aged Mice.

Frontiers in aging neuroscience

Huang L,Tian W,Chen X,Xu H,Dai W,Zhang Y,Wu X,Yu W,Tian J,Su D

Published figure using NK1.1 monoclonal antibody (Product # 56-5941-82) in Flow Cytometry

Mon Mar 14 00:00:00 EDT 2022

NK cells require immune checkpoint receptor LILRB4/gp49B to control neurotropic Zika virus infections in mice.

JCI insight

Lee HN,Manangeeswaran M,Lewkowicz AP,Engel K,Chowdhury M,Garige M,Eckhaus MA,Sourbier C,Ireland DD,Verthelyi D

Published figure using NK1.1 monoclonal antibody (Product # 56-5941-82) in Flow Cytometry

Tue Feb 08 00:00:00 EST 2022

Valosin-containing protein (VCP/p97) inhibition reduces viral clearance and induces toxicity associated with muscular damage.

Cell death & disease

Del Rio Oliva M,Basler M

Published figure using NK1.1 monoclonal antibody (Product # 56-5941-82) in Flow Cytometry

Thu Dec 01 00:00:00 EST 2022

A novel ZsGreen knock-in melanoma cell line reveals the function of CD11b in tumor phagocytosis.

Immunology and cell biology

Zhang L,Feng X,Shen Y,Wang Y,Liu Z,Ma Y,Gu Y,Guo G,Duan L,Lu L,Liang Y,Lawrence T,Huang R

56-5941-82 was used in Flow cytometry/Cell sorting to demonstrate that the ZsGreen-expressing YUMM1.7 melanoma model provides a valuable tool for the study of phagocytosis in vivo.

Sat Oct 01 00:00:00 EDT 2022

IL-22 initiates an IL-18-dependent epithelial response circuit to enforce intestinal host defence.

Nature communications

Chiang HY,Lu HH,Sudhakar JN,Chen YW,Shih NS,Weng YT,Shui JW

56-5941-82 was used in Flow Cytometry to conclude that IL-18 in return regulates Stat3-mediated anti-microbial response in Paneth cells, Akt-Tcf4-triggered expansion of Lgr5+ stem cells to facilitate tissue repair, and AIEC clearance by promoting IFNγ+ T cells.

Tue Feb 15 00:00:00 EST 2022

The transcriptional repressor ID2 supports natural killer cell maturation by controlling TCF1 amplitude.

The Journal of experimental medicine

Li ZY,Morman RE,Hegermiller E,Sun M,Bartom ET,Maienschein-Cline M,Sigvardsson M,Kee BL

Published figure using NK1.1 monoclonal antibody (Product # 56-5941-82) in Flow Cytometry

Mon Jun 07 00:00:00 EDT 2021

Chronic T cell proliferation in brains after stroke could interfere with the efficacy of immunotherapies.

The Journal of experimental medicine

Heindl S,Ricci A,Carofiglio O,Zhou Q,Arzberger T,Lenart N,Franzmeier N,Hortobagyi T,Nelson PT,Stowe AM,Denes A,Edbauer D,Liesz A

56-5941-82 was used in Flow Cytometry to show a persistent accumulation of T cells in mice and human autopsy samples for more than 1 mo after stroke.

Mon Aug 02 00:00:00 EDT 2021

Chronic T cell proliferation in brains after stroke could interfere with the efficacy of immunotherapies.

The Journal of experimental medicine

Heindl S,Ricci A,Carofiglio O,Zhou Q,Arzberger T,Lenart N,Franzmeier N,Hortobagyi T,Nelson PT,Stowe AM,Denes A,Edbauer D,Liesz A

56-5941-82 was used in Flow Cytometry to show a persistent accumulation of T cells in mice and human autopsy samples for more than 1 mo after stroke.

Mon Aug 02 00:00:00 EDT 2021

The Effect of miR-520b on Macrophage Polarization and T Cell Immunity by Targeting PTEN in Breast Cancer.

Journal of oncology

Zhu Q,Yuan J,He Y,Hu Y

Published figure using NK1.1 monoclonal antibody (Product # 56-5941-82) in Immunohistochemistry

Wed Apr 27 00:00:00 EDT 2022

Exosomal lncRNA SNHG10 derived from colorectal cancer cells suppresses natural killer cell cytotoxicity by upregulating INHBC.

Cancer cell international

Huang Y,Luo Y,Ou W,Wang Y,Dong D,Peng X,Luo Y

Published figure using NK1.1 monoclonal antibody (Product # 56-5941-82) in Flow Cytometry

Tue Oct 12 00:00:00 EDT 2021

Expression of CCRL2 Inhibits Tumor Growth by Concentrating Chemerin and Inhibiting Neoangiogenesis.

Cancers

Al Delbany D,Robert V,Dubois-Vedrenne I,Del Prete A,Vernimmen M,Radi A,Lefort A,Libert F,Wittamer V,Sozzani S,Parmentier M

Published figure using NK1.1 monoclonal antibody (Product # 56-5941-82) in Flow Cytometry

Tue Oct 05 00:00:00 EDT 2021

Near-infrared photoimmunotherapy targeting human-EGFR in a mouse tumor model simulating current and future clinical trials.

EBioMedicine

Okada R,Furusawa A,Vermeer DW,Inagaki F,Wakiyama H,Kato T,Nagaya T,Choyke PL,Spanos WC,Allen CT,Kobayashi H

Published figure using NK1.1 monoclonal antibody (Product # 56-5941-82) in Flow Cytometry

Sat May 01 00:00:00 EDT 2021

A novel miR1983-TLR7-IFNβ circuit licenses NK cells to kill glioma cells, and is under the control of galectin-1.

Oncoimmunology

Shah D,Comba A,Faisal SM,Kadiyala P,Baker GJ,Alghamri MS,Doherty R,Zamler D,Nuñez G,Castro MG,Lowenstein PR

Published figure using NK1.1 monoclonal antibody (Product # 56-5941-82) in Flow Cytometry

Mon Aug 02 00:00:00 EDT 2021

Histone deacetylase 3 represses cholesterol efflux during CD4⁺ T-cell activation.

eLife

Wilfahrt D,Philips RL,Lama J,Kizerwetter M,Shapiro MJ,McCue SA,Kennedy MM,Rajcula MJ,Zeng H,Shapiro VS

Published figure using NK1.1 monoclonal antibody (Product # 56-5941-82) in Protein Assays and Analysis

Thu Dec 02 00:00:00 EST 2021

Effects of Obesity-Associated Chronic Inflammation on Peripheral Blood Immunophenotype Are Not Mediated by TNF in Female C57BL/6J Mice.

ImmunoHorizons

Breznik JA,Foley KP,Maddiboina D,Schertzer JD,Sloboda DM,Bowdish DME

56-5941-82 was used in Flow Cytometry to characterize how TNF alters circulating cellular immunity in female mice with diet-induced obesity.

Fri Jun 04 00:00:00 EDT 2021

Sequencing, cloning, and antigen binding analysis of monoclonal antibodies isolated from single mouse B cells.

STAR protocols

Viant C,Escolano A,Chen ST,Nussenzweig MC

Published figure using NK1.1 monoclonal antibody (Product # 56-5941-82) in Flow Cytometry

Fri Jun 18 00:00:00 EDT 2021

The enrichment of neutrophil extracellular traps impair the placentas of systemic lupus erythematosus through accumulating decidual NK cells.

Scientific reports

Jiang M,Shen N,Zhou H,Wang Y,Lin S,Wu J,Di W

Published figure using NK1.1 monoclonal antibody (Product # 56-5941-82) in Flow Cytometry

Thu Mar 25 00:00:00 EDT 2021

Microbiota triggers STING-type I IFN-dependent monocyte reprogramming of the tumor microenvironment.

Cell

Lam KC,Araya RE,Huang A,Chen Q,Di Modica M,Rodrigues RR,Lopès A,Johnson SB,Schwarz B,Bohrnsen E,Cogdill AP,Bosio CM,Wargo JA,Lee MP,Goldszmid RS

56-5941-82 was used in Flow cytometry/Cell sorting to uncover a mechanistic link between the microbiota and the innate TME that can be harnessed to improve cancer therapies.

Thu Oct 14 00:00:00 EDT 2021

IFN-Stimulated Gene 15 Is an Alarmin that Boosts the CTL Response via an Innate, NK Cell-Dependent Route.

Journal of immunology (Baltimore, Md. : 1950)

Iglesias-Guimarais V,Ahrends T,de Vries E,Knobeloch KP,Volkov A,Borst J

56-5941 was used in Flow cytometry/Cell sorting to conclude that free ISG15 is part of a newly recognized innate route to promote the CTL response.

Wed Apr 15 00:00:00 EDT 2020

Analysis of Myeloid Cells in Mouse Tissues with Flow Cytometry.

STAR protocols

Liu Z,Gu Y,Shin A,Zhang S,Ginhoux F

Published figure using NK1.1 monoclonal antibody (Product # 56-5941-82) in Flow Cytometry

Fri Jun 19 00:00:00 EDT 2020

5-Azacytidine Potentiates Anti-tumor Immunity in a Model of Pancreatic Ductal Adenocarcinoma.

Frontiers in immunology

Ebelt ND,Zuniga E,Johnson BL,Diamond DJ,Manuel ER

56-5941 was used in Flow cytometry/Cell sorting to show that transposable elements (TE) and gene encoded, tumor-associated antigens (TAA) are significantly upregulated during the transition from pre-malignancy to malignancy in an inducible model of pancreatic ductal adenocarcinoma (PDAC).

Fri Mar 26 00:00:00 EDT 2021

Dendritic Cells and Myeloid Derived Suppressor Cells Fully Responsive to Stimulation via Toll-Like Receptor 4 Are Rapidly Induced from Bone-Marrow Cells by Granulocyte-Macrophage Colony-Stimulating Factor.

Vaccines

Kong YY,Wilson K,Apostolopoulos V,Plebanski M

Published figure using NK1.1 monoclonal antibody (Product # 56-5941-82) in Flow Cytometry

Sat Sep 12 00:00:00 EDT 2020

Immunization expands B cells specific to HIV-1 V3 glycan in mice and macaques.

Nature

Escolano A,Gristick HB,Abernathy ME,Merkenschlager J,Gautam R,Oliveira TY,Pai J,West AP,Barnes CO,Cohen AA,Wang H,Golijanin J,Yost D,Keeffe JR,Wang Z,Zhao P,Yao KH,Bauer J,Nogueira L,Gao H,Voll AV,Montefiori DC,Seaman MS,Gazumyan A,Silva M,McGuire AT,Stamatatos L,Irvine DJ,Wells L,Martin MA,Bjorkman PJ,Nussenzweig MC

Published figure using NK1.1 monoclonal antibody (Product # 56-5941-82) in Flow Cytometry

Sat Jun 01 00:00:00 EDT 2019

Expression of Bioactive Chemerin by Keratinocytes Inhibits Late Stages of Tumor Development in a Chemical Model of Skin Carcinogenesis.

Frontiers in oncology

Dubois-Vedrenne I,De Henau O,Robert V,Langa F,Javary J,Al Delbany D,Vosters O,Angelats-Canals E,Vernimmen M,Luangsay S,Wittamer V,Parmentier M

Published figure using NK1.1 monoclonal antibody (Product # 56-5941-82) in Flow Cytometry

Mon Sep 28 00:00:00 EDT 2020

Deletion of C-C Motif Chemokine Ligand 5 Worsens Invariant Natural Killer T-Cell-Mediated Hepatitis via Compensatory Up-regulation of CXCR2-Related Chemokine Activity.

Cellular and molecular gastroenterology and hepatology

Chen L,Gu J,Qian Y,Li M,Qian Y,Xu M,Li J,Wen Y,Xia L,Li J,Xia Q,Kong X,Wu H

Published figure using NK1.1 monoclonal antibody (Product # 56-5941-82) in Flow Cytometry

Tue Jun 04 00:00:00 EDT 2019

Synergized regulation of NK cell education by NKG2A and specific Ly49 family members.

Nature communications

Zhang X,Feng J,Chen S,Yang H,Dong Z

Published figure using NK1.1 monoclonal antibody (Product # 56-5941-82) in Flow Cytometry

Fri Nov 01 00:00:00 EDT 2019

Progranulin prevents regulatory NK cell cytotoxicity against antiviral T cells.

JCI insight

Huang A,Shinde PV,Huang J,Senff T,Xu HC,Margotta C,Häussinger D,Willnow TE,Zhang J,Pandyra AA,Timm J,Weggen S,Lang KS,Lang PA

Published figure using NK1.1 monoclonal antibody (Product # 56-5941-82) in Flow Cytometry

Thu Sep 05 00:00:00 EDT 2019

Antitumor immunity augments the therapeutic effects of p53 activation on acute myeloid leukemia.

Nature communications

Hayashi Y,Goyama S,Liu X,Tamura M,Asada S,Tanaka Y,Fukuyama T,Wunderlich M,O'Brien E,Mizukawa B,Yamazaki S,Matsumoto A,Yamasaki S,Shibata T,Matsuda K,Sashida G,Takizawa H,Kitamura T

Published figure using NK1.1 monoclonal antibody (Product # 56-5941-82) in Flow Cytometry

Fri Oct 25 00:00:00 EDT 2019

The Obese Liver Environment Mediates Conversion of NK Cells to a Less Cytotoxic ILC1-Like Phenotype.

Frontiers in immunology

Cuff AO,Sillito F,Dertschnig S,Hall A,Luong TV,Chakraverty R,Male V

Published figure using NK1.1 monoclonal antibody (Product # 56-5941-82) in Flow Cytometry

Wed Oct 21 00:00:00 EDT 2020

Tissue-specific shaping of the TCR repertoire and antigen specificity of iNKT cells.

eLife

Jimeno R,Lebrusant-Fernandez M,Margreitter C,Lucas B,Veerapen N,Kelly G,Besra GS,Fraternali F,Spencer J,Anderson G,Barral P

Published figure using NK1.1 monoclonal antibody (Product # 56-5941-82) in Flow Cytometry

Mon Dec 16 00:00:00 EST 2019

Fc Effector Function Contributes to the Activity of Human Anti-CTLA-4 Antibodies.

Cancer cell

Arce Vargas F,Furness AJS,Litchfield K,Joshi K,Rosenthal R,Ghorani E,Solomon I,Lesko MH,Ruef N,Roddie C,Henry JY,Spain L,Ben Aissa A,Georgiou A,Wong YNS,Smith M,Strauss D,Hayes A,Nicol D,O'Brien T,Mårtensson L,Ljungars A,Teige I,Frendéus B,Pule M,Marafioti T,Gore M,Larkin J,Turajlic S,Swanton C,Peggs KS,Quezada SA

56-5941 was used in Flow cytometry/Cell sorting to examine the importance of Fc-gamma receptor binding in contributing to the activity of anti-CTLA4 antibodies.

Mon Apr 09 00:00:00 EDT 2018

CD8⁺ T cells mediate the antitumor activity of frankincense and myrrh in hepatocellular carcinoma.

Journal of translational medicine

Xu C,Lu X,Liu W,Chen A,Meng G,Zhang H,Li B,Zhang Y,Wu J,Wei J

Published figure using NK1.1 monoclonal antibody (Product # 56-5941-82) in Flow Cytometry

Mon May 21 00:00:00 EDT 2018

Plasmodium co-infection protects against chikungunya virus-induced pathologies.

Nature communications

Teo TH,Lum FM,Ghaffar K,Chan YH,Amrun SN,Tan JJL,Lee CYP,Chua TK,Carissimo G,Lee WWL,Claser C,Rajarethinam R,Rénia L,Ng LFP

Published figure using NK1.1 monoclonal antibody (Product # 56-5941-82) in Flow Cytometry

Tue Sep 25 00:00:00 EDT 2018

Differentiation of human and murine induced pluripotent stem cells to microglia-like cells.

Nature neuroscience

Pandya H,Shen MJ,Ichikawa DM,Sedlock AB,Choi Y,Johnson KR,Kim G,Brown MA,Elkahloun AG,Maric D,Sweeney CL,Gossa S,Malech HL,McGavern DB,Park JK

Published figure using NK1.1 monoclonal antibody (Product # 56-5941-82) in Flow Cytometry

Mon May 01 00:00:00 EDT 2017

A TLR7 agonist enhances the antitumor efficacy of obinutuzumab in murine lymphoma models via NK cells and CD4 T cells.

Leukemia

Cheadle EJ,Lipowska-Bhalla G,Dovedi SJ,Fagnano E,Klein C,Honeychurch J,Illidge TM

Published figure using NK1.1 monoclonal antibody (Product # 56-5941-82) in Flow Cytometry

Sat Jul 01 00:00:00 EDT 2017

IL-2/Anti-IL-2 Complex Attenuates Inflammation and BBB Disruption in Mice Subjected to Traumatic Brain Injury.

Frontiers in neurology

Gao W,Li F,Zhou Z,Xu X,Wu Y,Zhou S,Yin D,Sun D,Xiong J,Jiang R,Zhang J

Published figure using NK1.1 monoclonal antibody (Product # 56-5941-82) in Flow Cytometry

Thu Oct 01 00:00:00 EDT 2020

Loss of HIF-1α in natural killer cells inhibits tumour growth by stimulating non-productive angiogenesis.

Nature communications

Krzywinska E,Kantari-Mimoun C,Kerdiles Y,Sobecki M,Isagawa T,Gotthardt D,Castells M,Haubold J,Millien C,Viel T,Tavitian B,Takeda N,Fandrey J,Vivier E,Sexl V,Stockmann C

Published figure using NK1.1 monoclonal antibody (Product # 56-5941-82) in Flow Cytometry

Fri Nov 17 00:00:00 EST 2017

The breast tumor microenvironment alters the phenotype and function of natural killer cells.

Cellular & molecular immunology

Krneta T,Gillgrass A,Chew M,Ashkar AA

Published figure using NK1.1 monoclonal antibody (Product # 56-5941-82) in Flow Cytometry

Thu Sep 01 00:00:00 EDT 2016

Hypoxia-Inducible Factor-2α Limits Natural Killer T Cell Cytotoxicity in Renal Ischemia/Reperfusion Injury.

Journal of the American Society of Nephrology : JASN

Zhang J,Han C,Dai H,Hou J,Dong Y,Cui X,Xu L,Zhang M,Xia Q

Published figure using NK1.1 monoclonal antibody (Product # 56-5941-82) in Flow Cytometry

Fri Jan 01 00:00:00 EST 2016

Adipose tissue adaptive response to trans-10,cis-12-conjugated linoleic acid engages alternatively activated M2 macrophages.

FASEB journal : official publication of the Federation of American Societies for Experimental Biology

Pini M,Touch S,Poirier H,Dalmas E,Niot I,Rouault C,Druart C,Delzenne N,Clément K,André S,Guerre-Millo M

56-5941 was used in Flow cytometry/Cell sorting to reveal a striking resilience of white adipose tissue after a short-term metabolic injury induced by t10,c12-CLA, which relies on alternatively activated M2 macrophage engagement.

Fri Jan 01 00:00:00 EST 2016

NK cell development requires Tsc1-dependent negative regulation of IL-15-triggered mTORC1 activation.

Nature communications

Yang M,Chen S,Du J,He J,Wang Y,Li Z,Liu G,Peng W,Zeng X,Li D,Xu P,Guo W,Chang Z,Wang S,Tian Z,Dong Z

Published figure using NK1.1 monoclonal antibody (Product # 56-5941-82) in Flow Cytometry

Wed Sep 07 00:00:00 EDT 2016

Favorable alteration of tumor microenvironment by immunomodulatory cytokines for efficient T-cell therapy in solid tumors.

PloS one

Tähtinen S,Kaikkonen S,Merisalo-Soikkeli M,Grönberg-Vähä-Koskela S,Kanerva A,Parviainen S,Vähä-Koskela M,Hemminki A

Published figure using NK1.1 monoclonal antibody (Product # 56-5941-82) in Flow Cytometry

Thu Apr 28 00:00:00 EDT 2016

Metronomic cyclophosphamide eradicates large implanted GL261 gliomas by activating antitumor Cd8⁺ T-cell responses and immune memory.

Oncoimmunology

Wu J,Waxman DJ

Published figure using NK1.1 monoclonal antibody (Product # 56-5941-82) in Flow Cytometry

Wed Apr 01 00:00:00 EDT 2015

Leukocyte population dynamics and detection of IL-9 as a major cytokine at the mouse fetal-maternal interface.

PloS one

Habbeddine M,Verbeke P,Karaz S,Bobé P,Kanellopoulos-Langevin C

Published figure using NK1.1 monoclonal antibody (Product # 56-5941-82) in Flow Cytometry

Wed Jun 10 00:00:00 EDT 2015

VEGF receptor inhibitors block the ability of metronomically dosed cyclophosphamide to activate innate immunity-induced tumor regression.

Cancer research

Doloff JC,Waxman DJ

Published figure using NK1.1 monoclonal antibody (Product # 56-5941-82) in Flow Cytometry

Thu Mar 01 00:00:00 EST 2012

Bioinformatics

Protein Aliases: CD161 antigen-like family member B; CD161 antigen-like family member C; CD161b; CD161c; Inhibitory receptor NKR-P1B; killer cell lectin-like receptor subfamily A member 1C; killer cell lectin-like receptor subfamily B member 1B allele A; Killer cell lectin-like receptor subfamily B member 1B allele B; Killer cell lectin-like receptor subfamily B member 1C; killer cell lectin-like receptor subfamily B member 1D; KLRB1; Ly-55; ly-55b; Ly-55c; Ly-55d; Ly55; lymphocyte antigen 55 complex, locus B; lymphocyte antigen 55 complex, locus C; lymphocyte antigen 55 complex, locus D; lymphocyte antigen 55b; Lymphocyte antigen 55c; Lymphocyte antigen 55d; lymphocyte antigen 59; MGC163757; MGC163759; natural killer cell receptor protein NKR-P1B; natural killer cell receptor protein NKR-P1C; natural killer cell receptor-P1; Natural killer cell surface protein NKR-P1B allele B6; natural killer cell surface protein NKR-P1B allele SJL/BALB; Natural killer cell surface protein P1-40; natural killer cell-associated antigen 1; natural killer cells; nk cells; NK1.1; NKR-P1 34; NKR-P1 40; NKR-P1.9; NKR-P1C; NKR-P1D

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Gene Aliases: AI462337; CD161; Klrb1b; Klrb1c; Klrb1d; ly-55c; Ly-59; Ly55b; Ly55c; Ly55d; Ly59; Nk-1; Nk-1.2; NK-RP1; Nk1; NK1.1; Nk1.2; NKR-P1.9; NKR-P1B; NKR-P1D; NKRP1; Nkrp1-b; NKRP140; Nkrp1b; Nkrp1c; Nkrp1d

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UniProt ID: (Mouse) Q99JB4, (Mouse) P27814

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Entrez Gene ID: (Mouse) 80782, (Mouse) 17059

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Function(s)

receptor activity protein binding carbohydrate binding protein homodimerization activity transmembrane signal receptor

Process(es)

negative regulation of natural killer cell mediated cytotoxicity natural killer cell activation positive regulation of natural killer cell mediated cytotoxicity

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If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*

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NK1.1 Monoclonal Antibody (PK136), Alexa Fluor™ 700, eBioscience™

NK1.1 Antibody (56-5941-82) in Flow

Product Details

56-5941-82

Immunohistochemistry (IHC)

Flow Cytometry (Flow)

Miscellaneous PubMed (Misc)

Species Reactivity

Published species

Host/Isotype

Recommended Isotype Control

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Conjugate

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Concentration

Purification

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Contains

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