Product References
Respiratory mucosal vaccination of peptide-poloxamine-DNA nanoparticles provides complete protection against lethal SARS-CoV-2 challenge.
Biomaterials
Sun S,Li E,Zhao G,Tang J,Zuo Q,Cai L,Xu C,Sui C,Ou Y,Liu C,Li H,Ding Y,Li C,Lu D,Zhang W,Luo P,Cheng P,Gao Y,Tu C,Pitard B,Rosenecker J,Wang B,Liu Y,Zou Q,Guan S
Published figure using CD4 monoclonal antibody (Product # 56-0041-82) in Flow Cytometry
Sun Jan 01 00:00:00 EST 2023
HSF1 promotes CD69+ Treg differentiation to inhibit colitis progression.
Theranostics
Yu L,Zhou B,Zhu Y,Li L,Zhong Y,Zhu L,Wang H,Chen H,Xu J,Guo T,Feng L,Wang X,Cai Z,Wang J,Jin H
Published figure using CD4 monoclonal antibody (Product # 56-0041-82) in Flow Cytometry
Tue Apr 18 00:00:00 EDT 2023
Selective neuroimmune modulation by type I interferon drives neuropathology and neurologic dysfunction following traumatic brain injury.
Acta neuropathologica communications
Todd BP,Luo Z,Gilkes N,Chimenti MS,Peterson Z,Mix MR,Harty JT,Nickl-Jockschat T,Ferguson PJ,Bassuk AG,Newell EA
56-0041-82 was used in Flow cytometry/Cell sorting to support further efforts to leverage the IFN-I pathway for novel, targeted therapy of TBI.
Fri Aug 18 00:00:00 EDT 2023
Prolidase Deficiency Causes Spontaneous T Cell Activation and Lupus-like Autoimmunity.
Journal of immunology (Baltimore, Md. : 1950)
Hodgson R,Crockford TL,Bhandari A,Kepple JD,Back J,Cawthorne E,Abeler-Dörner L,Laing AG,Clare S,Speak A,Adams DJ,Dougan G,Hayday AC,Deobagkar-Lele M,Cornall RJ,Bull KR
Published figure using CD4 monoclonal antibody (Product # 56-0041-82) in Flow Cytometry
Wed Mar 01 00:00:00 EST 2023
Toll-like receptor mediated inflammation directs B cells towards protective antiviral extrafollicular responses.
Nature communications
Lam JH,Baumgarth N
56-0041-82 was used in Flow cytometry/Cell sorting to show that influenza infection rapidly induces EFRs, generating protective antibodies via Toll-like receptor (TLR)-mediated mechanisms that are both B cell intrinsic and extrinsic.
Wed Jul 05 00:00:00 EDT 2023
Development of a Syrian hamster anti-PD-L1 monoclonal antibody enables oncolytic adenoviral immunotherapy modelling in an immunocompetent virus replication permissive setting.
Frontiers in immunology
Clubb JHA,Kudling TV,Girych M,Haybout L,Pakola S,Hamdan F,Cervera-Carrascon V,Hemmes A,Grönberg-Vähä-Koskela S,Santos JM,Quixabeira DCA,Basnet S,Heiniö C,Arias V,Jirovec E,Kaptan S,Havunen R,Sorsa S,Erikat A,Schwartz J,Anttila M,Aro K,Viitala T,Vattulainen I,Cerullo V,Kanerva A,Hemminki A
Published figure using CD4 monoclonal antibody (Product # 56-0041-82) in Flow Cytometry
Mon Feb 27 00:00:00 EST 2023
GH18 family glycoside hydrolase Chitinase A of Salmonella enhances virulence by facilitating invasion and modulating host immune responses.
PLoS pathogens
Chandra K,Roy Chowdhury A,Chatterjee R,Chakravortty D
Published figure using CD4 monoclonal antibody (Product # 56-0041-82) in Flow Cytometry
Fri Apr 01 00:00:00 EDT 2022
Rotenone aggravates PD-like pathology in A53T mutant human α-synuclein transgenic mice in an age-dependent manner.
Frontiers in aging neuroscience
Chen AD,Cao JX,Chen HC,Du HL,Xi XX,Sun J,Yin J,Jing YH,Gao LP
Published figure using CD4 monoclonal antibody (Product # 56-0041-82) in Flow Cytometry
Fri Aug 26 00:00:00 EDT 2022
IL-33 Deficiency Attenuates Lung Inflammation by Inducing Th17 Response and Impacting the Th17/Treg Balance in LPS-Induced ARDS Mice via Dendritic Cells.
Journal of immunology research
Cheng L,Jiao Y,Jiang W,Zhang X,Zhang L,Jia G
Published figure using CD4 monoclonal antibody (Product # 56-0041-82) in Flow Cytometry
Tue Dec 27 00:00:00 EST 2022
Interferon-γ Stimulates Interleukin-27 Derived from Dendritic Cells to Regulate Th9 Differentiation through STAT1/3 Pathway.
Disease markers
Xiong P,Liu T,Chen Y,Xu Q,Hu X,Han F,Shi L
Published figure using CD4 monoclonal antibody (Product # 56-0041-82) in Flow Cytometry
Mon Oct 31 00:00:00 EDT 2022
CD4+ CTLs Act as a Key Effector Population for Allograft Rejection of MSCs in a Donor MHC-II Dependent Manner in Injured Liver.
Aging and disease
Shen S,Li Y,Jin M,Fan D,Pan R,Lin A,Chen Y,Xiang L,Zhao RC,Shao J
Published figure using CD4 monoclonal antibody (Product # 56-0041-82) in Flow Cytometry
Thu Dec 01 00:00:00 EST 2022
Free Fatty Acid Receptor 4 (FFA4) Activation Ameliorates Imiquimod-Induced Psoriasis in Mice.
International journal of molecular sciences
Son SE,Koh JM,Im DS
Published figure using CD4 monoclonal antibody (Product # 56-0041-82) in Flow Cytometry
Tue Apr 19 00:00:00 EDT 2022
Btla signaling in conventional and regulatory lymphocytes coordinately tempers humoral immunity in the intestinal mucosa.
Cell reports
Stienne C,Virgen-Slane R,Elmén L,Veny M,Huang S,Nguyen J,Chappell E,Balmert MO,Shui JW,Hurchla MA,Kronenberg M,Peterson SN,Murphy KM,Ware CF,Šedý JR
Published figure using CD4 monoclonal antibody (Product # 56-0041-82) in Immunohistochemistry
Tue Mar 22 00:00:00 EDT 2022
Valosin-containing protein (VCP/p97) inhibition reduces viral clearance and induces toxicity associated with muscular damage.
Cell death & disease
Del Rio Oliva M,Basler M
Published figure using CD4 monoclonal antibody (Product # 56-0041-82) in Flow Cytometry
Thu Dec 01 00:00:00 EST 2022
Lipid A analog CRX-527 conjugated to synthetic peptides enhances vaccination efficacy and tumor control.
NPJ vaccines
Tondini E,Reintjens NRM,Castello G,Arakelian T,Isendoorn M,Camps M,Vree J,van der Marel GA,Filippov DV,Codee JDC,Ossendorp F
56-0041-82 was used in Flow cytometry/Cell sorting to highlight the potential of CRX-527 as an adjuvant for molecularly defined cancer vaccines, and support the design of adjuvant-peptide conjugates as a strategy to optimize vaccine formulation.
Thu Jun 23 00:00:00 EDT 2022
Engineered immunomodulatory accessory cells improve experimental allogeneic islet transplantation without immunosuppression.
Science advances
Wang X,Wang K,Yu M,Velluto D,Hong X,Wang B,Chiu A,Melero-Martin JM,Tomei AA,Ma M
56-0041-82 was used in Flow cytometry/Cell sorting to suggest that the eMSCs can induce local immunomodulation and may be applicable in clinical islet transplantation to reduce or minimize the need of systemic immunosuppression and ameliorate its negative impact.
Fri Jul 22 00:00:00 EDT 2022
P140 Peptide Leads to Clearance of Autoreactive Lymphocytes and Normalizes Immune Response in Lupus-Prone Mice.
Frontiers in immunology
Schall N,Talamini L,Wilhelm M,Jouvin-Marche E,Muller S
56-0041-82 was used in Flow cytometry/Cell sorting to suggest that P140 belongs to a new family of non-immunosuppressive immunoregulators that do not correct T and B cell abnormalities but rather contribute to the clearance of deleterious T and B cells.
Tue Jun 21 00:00:00 EDT 2022
Ribosome-Targeting Antibiotics Impair T Cell Effector Function and Ameliorate Autoimmunity by Blocking Mitochondrial Protein Synthesis.
Immunity
Almeida L,Dhillon-LaBrooy A,Castro CN,Adossa N,Carriche GM,Guderian M,Lippens S,Dennerlein S,Hesse C,Lambrecht BN,Berod L,Schauser L,Blazar BR,Kalesse M,Müller R,Moita LF,Sparwasser T
Published figure using CD4 monoclonal antibody (Product # 56-0041-82) in Flow Cytometry
Tue Jan 12 00:00:00 EST 2021
Cell-mimicking nanodecoys neutralize SARS-CoV-2 and mitigate lung injury in a non-human primate model of COVID-19.
Nature nanotechnology
Li Z,Wang Z,Dinh PC,Zhu D,Popowski KD,Lutz H,Hu S,Lewis MG,Cook A,Andersen H,Greenhouse J,Pessaint L,Lobo LJ,Cheng K
Published figure using CD4 monoclonal antibody (Product # 56-0041-82) in Immunocytochemistry
Sun Aug 01 00:00:00 EDT 2021
NF-κB-inducing kinase maintains T cell metabolic fitness in antitumor immunity.
Nature immunology
Gu M,Zhou X,Sohn JH,Zhu L,Jie Z,Yang JY,Zheng X,Xie X,Yang J,Shi Y,Brightbill HD,Kim JB,Wang J,Cheng X,Sun SC
Published figure using CD4 monoclonal antibody (Product # 56-0041-82) in Flow Cytometry
Mon Feb 01 00:00:00 EST 2021
Porphyromonas gingivalis exacerbates ulcerative colitis via Porphyromonas gingivalis peptidylarginine deiminase.
International journal of oral science
Zhao X,Liu J,Zhang C,Yu N,Lu Z,Zhang S,Li Y,Li Q,Liu J,Liu D,Pan Y
Published figure using CD4 monoclonal antibody (Product # 56-0041-82) in Flow Cytometry
Thu Sep 30 00:00:00 EDT 2021
Uncovering a novel role of PLCβ4 in selectively mediating TCR signaling in CD8+ but not CD4+ T cells.
The Journal of experimental medicine
Sasai M,Ma JS,Okamoto M,Nishino K,Nagaoka H,Takashima E,Pradipta A,Lee Y,Kosako H,Suh PG,Yamamoto M
Published figure using CD4 monoclonal antibody (Product # 56-0041-82) in Flow Cytometry
Mon Jul 05 00:00:00 EDT 2021
CYBB/NOX2 in conventional DCs controls T cell encephalitogenicity during neuroinflammation.
Autophagy
Keller CW,Kotur MB,Mundt S,Dokalis N,Ligeon LA,Shah AM,Prinz M,Becher B,Münz C,Lünemann JD
56-0041-82 was used in Sample Preparation to report that the nicotinamide adenine dinucleotide phosphate (NADPH) oxidase 2, also known as CYBB/NOX2, in conventional DCs (cDCs) regulates endocytosed MOG (myelin oligodendrocyte protein) antigen processing and supports MOG-antigen presentation to CD4+ T cells through LC3-associated phagocytosis (LAP).
Sat May 01 00:00:00 EDT 2021
High Ambient Temperature Aggravates Experimental Autoimmune Uveitis Symptoms.
Frontiers in cell and developmental biology
Pan S,Tan H,Chang R,Wang Q,Zhu Y,Chen L,Li H,Su G,Zhou C,Cao Q,Kijlstra A,Yang P
Published figure using CD4 monoclonal antibody (Product # 56-0041-82) in Flow Cytometry
Tue Apr 13 00:00:00 EDT 2021
Dynamic changes in the systemic immune responses of spinal cord injury model mice.
Neural regeneration research
Gao TY,Huang FF,Xie YY,Wang WQ,Wang LD,Mu D,Cui Y,Wang B
Published figure using CD4 monoclonal antibody (Product # 56-0041-82) in Flow Cytometry
Mon Feb 01 00:00:00 EST 2021
Exploiting a Rose Bengal-bearing, oxygen-producing nanoparticle for SDT and associated immune-mediated therapeutic effects in the treatment of pancreatic cancer.
European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V
Nicholas D,Nesbitt H,Farrell S,Logan K,McMullin E,Gillan T,Kelly P,O'Rourke D,Porter S,Thomas K,O'Hagan BMG,Nomikou N,Callan B,Callan JF,McHale AP
56-0041-82 was used in Flow cytometry/Cell sorting to describe a robust means of preparing a pH-sensitive polymethacrylate-coated CaO2 nanoparticle that is capable of transiently alleviating tumour hypoxia.
Tue Jun 01 00:00:00 EDT 2021
Generation of a Novel Oncolytic Vaccinia Virus Using the IHD-W Strain.
Human gene therapy
Shin J,Hong SO,Kim M,Lee H,Choi H,Kim J,Hong J,Kang H,Lee E,Lee S,Kong B,Kim M,Choi H,Kim S
Published figure using CD4 monoclonal antibody (Product # 56-0041-82) in Flow Cytometry
Sat May 01 00:00:00 EDT 2021
CXCR3 alleviates renal ischemia‑reperfusion injury via increase of Tregs.
Molecular medicine reports
Xian W,Wu J,Li Q,Du X,Wang N,Chen D,Gao W,Cao J
Published figure using CD4 monoclonal antibody (Product # 56-0041-82) in Flow Cytometry
Thu Jul 01 00:00:00 EDT 2021
Irradiated whole-cell vaccine suppresses hepatocellular carcinoma growth in mice via Th9 cells.
Oncology letters
Chen J,Ding Y,Huang F,Lan R,Wang Z,Huang W,Chen R,Wu B,Fu L,Yang Y,Liu J,Hong J,Zhang W,Zhang L
Published figure using CD4 monoclonal antibody (Product # 56-0041-82) in Flow Cytometry
Sat May 01 00:00:00 EDT 2021
Preliminary analysis of immunoregulatory mechanism of hyperhomocysteinemia-induced brain injury in Wistar-Kyoto rats.
Experimental and therapeutic medicine
Zhang Y,Wang L,Li X,Geng J
Published figure using CD4 monoclonal antibody (Product # 56-0041-82) in Flow Cytometry
Sat May 01 00:00:00 EDT 2021
Estrogen receptor beta signaling in CD8+ T cells boosts T cell receptor activation and antitumor immunity through a phosphotyrosine switch.
Journal for immunotherapy of cancer
Yuan B,Clark CA,Wu B,Yang J,Drerup JM,Li T,Jin VX,Hu Y,Curiel TJ,Li R
Published figure using CD4 monoclonal antibody (Product # 56-0041-82) in Flow Cytometry
Fri Jan 01 00:00:00 EST 2021
TNFRSF13B genotypes control immune-mediated pathology by regulating the functions of innate B cells.
JCI insight
de Mattos Barbosa MG,Lefferts AR,Huynh D,Liu H,Zhang Y,Fu B,Barnes J,Samaniego M,Bram RJ,Geha RS,Shikanov A,Prak ETL,Farkash EA,Platt JL,Cascalho M
Published figure using CD4 monoclonal antibody (Product # 56-0041-82) in Immunohistochemistry
Wed Sep 08 00:00:00 EDT 2021
Neuroimmune Consequences of eIF4E Phosphorylation on Chemotherapy-Induced Peripheral Neuropathy.
Frontiers in immunology
Agalave NM,Mody PH,Szabo-Pardi TA,Jeong HS,Burton MD
Published figure using CD4 monoclonal antibody (Product # 56-0041-82) in Flow Cytometry
Mon Sep 20 00:00:00 EDT 2021
Alphavirus-Driven Interferon Gamma (IFNg) Expression Inhibits Tumor Growth in Orthotopic 4T1 Breast Cancer Model.
Vaccines
Trofimova O,Korotkaja K,Skrastina D,Jansons J,Spunde K,Isaguliants M,Zajakina A
Published figure using CD4 monoclonal antibody (Product # 56-0041-82) in Flow Cytometry
Wed Oct 27 00:00:00 EDT 2021
A lymph node-targeted Amphiphile vaccine induces potent cellular and humoral immunity to SARS-CoV-2.
Science advances
Steinbuck MP,Seenappa LM,Jakubowski A,McNeil LK,Haqq CM,DeMuth PC
Published figure using CD4 monoclonal antibody (Product # 56-0041-82) in Flow Cytometry
Mon Feb 01 00:00:00 EST 2021
Positive Effects of Oral Antibiotic Administration in Murine Chronic Graft-Versus-Host Disease.
International journal of molecular sciences
Sato S,Shimizu E,He J,Ogawa M,Asai K,Yazu H,Rusch R,Yamane M,Yang F,Fukuda S,Kawakami Y,Tsubota K,Ogawa Y
Published figure using CD4 monoclonal antibody (Product # 56-0041-82) in Immunocytochemistry
Sat Apr 03 00:00:00 EDT 2021
Positive Effects of Oral Antibiotic Administration in Murine Chronic Graft-Versus-Host Disease.
International journal of molecular sciences
Sato S,Shimizu E,He J,Ogawa M,Asai K,Yazu H,Rusch R,Yamane M,Yang F,Fukuda S,Kawakami Y,Tsubota K,Ogawa Y
Published figure using CD4 monoclonal antibody (Product # 56-0041-82) in Immunocytochemistry
Sat Apr 03 00:00:00 EDT 2021
Functional inhibition of lactate dehydrogenase suppresses pancreatic adenocarcinoma progression.
Clinical and translational medicine
Cheng CS,Tan HY,Wang N,Chen L,Meng Z,Chen Z,Feng Y
Published figure using CD4 monoclonal antibody (Product # 56-0041-82) in Immunohistochemistry
Tue Jun 01 00:00:00 EDT 2021
IDO1 Expression in Ovarian Cancer Induces PD-1 in T Cells via Aryl Hydrocarbon Receptor Activation.
Frontiers in immunology
Amobi-McCloud A,Muthuswamy R,Battaglia S,Yu H,Liu T,Wang J,Putluri V,Singh PK,Qian F,Huang RY,Putluri N,Tsuji T,Lugade AA,Liu S,Odunsi K
Published figure using CD4 monoclonal antibody (Product # 56-0041-82) in Flow Cytometry
Fri Oct 29 00:00:00 EDT 2021
Mesenchymal stem cell exosome-derived miR-223 alleviates acute graft-versus-host disease via reducing the migration of donor T cells.
Stem cell research & therapy
Liu W,Zhou N,Liu Y,Zhang W,Li X,Wang Y,Zheng R,Zhang Y
Published figure using CD4 monoclonal antibody (Product # 56-0041-82) in Flow Cytometry
Fri Feb 26 00:00:00 EST 2021
G-MDSCs promote aging-related cardiac fibrosis by activating myofibroblasts and preventing senescence.
Cell death & disease
Sun SN,Ni SH,Li Y,Liu X,Deng JP,Chen ZX,Li H,Feng WJ,Huang YS,Li DN,Xian SX,Yang ZQ,Wang LJ,Lu L
Published figure using CD4 monoclonal antibody (Product # 56-0041-82) in Flow Cytometry
Tue Jun 08 00:00:00 EDT 2021
Butyrate Improves Skin/Lung Fibrosis and Intestinal Dysbiosis in Bleomycin-Induced Mouse Models.
International journal of molecular sciences
Park HJ,Jeong OY,Chun SH,Cheon YH,Kim M,Kim S,Lee SI
Published figure using CD4 monoclonal antibody (Product # 56-0041-82) in Flow Cytometry
Tue Mar 09 00:00:00 EST 2021
Butyrate Improves Skin/Lung Fibrosis and Intestinal Dysbiosis in Bleomycin-Induced Mouse Models.
International journal of molecular sciences
Park HJ,Jeong OY,Chun SH,Cheon YH,Kim M,Kim S,Lee SI
Published figure using CD4 monoclonal antibody (Product # 56-0041-82) in Flow Cytometry
Tue Mar 09 00:00:00 EST 2021
Mapping Rora expression in resting and activated CD4+ T cells.
PloS one
Haim-Vilmovsky L,Henriksson J,Walker JA,Miao Z,Natan E,Kar G,Clare S,Barlow JL,Charidemou E,Mamanova L,Chen X,Proserpio V,Pramanik J,Woodhouse S,Protasio AV,Efremova M,Griffin JL,Berriman M,Dougan G,Fisher J,Marioni JC,McKenzie ANJ,Teichmann SA
Published figure using CD4 monoclonal antibody (Product # 56-0041-82) in Flow Cytometry
Fri Nov 12 00:00:00 EST 2021
Type 2 diabetic mice enter a state of spontaneous hibernation-like suspended animation following accumulation of uric acid.
The Journal of biological chemistry
Zhao Y,Cheng R,Zhao Y,Ge W,Yang Y,Ding Z,Xu X,Wang Z,Wu Z,Zhang J
Published figure using CD4 monoclonal antibody (Product # 56-0041-82) in Flow Cytometry
Fri Oct 01 00:00:00 EDT 2021
Targeting Ovarian Carcinoma with TSP-1:CD47 Antagonist TAX2 Activates Anti-Tumor Immunity.
Cancers
Jeanne A,Sarazin T,Charlé M,Moali C,Fichel C,Boulagnon-Rombi C,Callewaert M,Andry MC,Diesis E,Delolme F,Rioult D,Dedieu S
Published figure using CD4 monoclonal antibody (Product # 56-0041-82) in Flow Cytometry
Thu Oct 07 00:00:00 EDT 2021
Targeting Ovarian Carcinoma with TSP-1:CD47 Antagonist TAX2 Activates Anti-Tumor Immunity.
Cancers
Jeanne A,Sarazin T,Charlé M,Moali C,Fichel C,Boulagnon-Rombi C,Callewaert M,Andry MC,Diesis E,Delolme F,Rioult D,Dedieu S
Published figure using CD4 monoclonal antibody (Product # 56-0041-82) in Flow Cytometry
Thu Oct 07 00:00:00 EDT 2021
A nanounit strategy reverses immune suppression of exosomal PD-L1 and is associated with enhanced ferroptosis.
Nature communications
Wang G,Xie L,Li B,Sang W,Yan J,Li J,Tian H,Li W,Zhang Z,Tian Y,Dai Y
Published figure using CD4 monoclonal antibody (Product # 56-0041-82) in Flow Cytometry
Thu Sep 30 00:00:00 EDT 2021
Oxygen-Enriched Metal-Phenolic X-Ray Nanoprocessor for Cancer Radio-Radiodynamic Therapy in Combination with Checkpoint Blockade Immunotherapy.
Advanced science (Weinheim, Baden-Wurttemberg, Germany)
Sang W,Xie L,Wang G,Li J,Zhang Z,Li B,Guo S,Deng CX,Dai Y
Published figure using CD4 monoclonal antibody (Product # 56-0041-82) in Flow Cytometry
Mon Feb 01 00:00:00 EST 2021
Systemic Delivery of Oncolytic Adenovirus to Tumors Using Tumor-Infiltrating Lymphocytes as Carriers.
Cells
Santos J,Heiniö C,Quixabeira D,Zafar S,Clubb J,Pakola S,Cervera-Carrascon V,Havunen R,Kanerva A,Hemminki A
Published figure using CD4 monoclonal antibody (Product # 56-0041-82) in Flow Cytometry
Thu Apr 22 00:00:00 EDT 2021
Aging-dependent mitochondrial dysfunction mediated by ceramide signaling inhibits antitumor T cell response.
Cell reports
Vaena S,Chakraborty P,Lee HG,Janneh AH,Kassir MF,Beeson G,Hedley Z,Yalcinkaya A,Sofi MH,Li H,Husby ML,Stahelin RV,Yu XZ,Mehrotra S,Ogretmen B
Published figure using CD4 monoclonal antibody (Product # 56-0041-82) in Immunocytochemistry
Tue May 04 00:00:00 EDT 2021
Milk-derived extracellular vesicles alleviate ulcerative colitis by regulating the gut immunity and reshaping the gut microbiota.
Theranostics
Tong L,Hao H,Zhang Z,Lv Y,Liang X,Liu Q,Liu T,Gong P,Zhang L,Cao F,Pastorin G,Lee CN,Chen X,Wang JW,Yi H
Published figure using CD4 monoclonal antibody (Product # 56-0041-82) in Flow Cytometry
Fri Jan 28 00:00:00 EST 2022
Inducible T-Cell Costimulator Mediates Lymphocyte/Macrophage Interactions During Liver Repair.
Frontiers in immunology
Ramavath NN,Gadipudi LL,Provera A,Gigliotti LC,Boggio E,Bozzola C,Albano E,Dianzani U,Sutti S
Published figure using CD4 monoclonal antibody (Product # 56-0041-82) in Flow Cytometry
Mon Feb 14 00:00:00 EST 2022
Remote Limb Ischemic Postconditioning Protects Against Ischemic Stroke by Promoting Regulatory T Cells Thriving.
Journal of the American Heart Association
Yu HH,Ma XT,Ma X,Chen M,Chu YH,Wu LJ,Wang W,Qin C,Tian DS
Published figure using CD4 monoclonal antibody (Product # 56-0041-82) in Flow Cytometry
Tue Nov 16 00:00:00 EST 2021
Activin A Promotes Regulatory T-cell-Mediated Immunosuppression in Irradiated Breast Cancer.
Cancer immunology research
De Martino M,Daviaud C,Diamond JM,Kraynak J,Alard A,Formenti SC,Miller LD,Demaria S,Vanpouille-Box C
56-0041-82 was used in Flow Cytometry to shed light on an immune escape mechanism driven by activin A and suggest that dual targeting of activin A and TGFβ may be required to optimally unleash radiation-induced antitumor immunity against breast cancer.
Fri Jan 01 00:00:00 EST 2021
Retinoic Acid Induces Functionally Suppressive Foxp3+RORγt+ T Cells In Vitro.
Frontiers in immunology
Martínez-Blanco M,Lozano-Ojalvo D,Pérez-Rodríguez L,Benedé S,Molina E,López-Fandiño R
56-0041-82 was used in Flow Cytometry to show that under the influence of IL-2 and TGF-β, suppressive Foxp3+RORγt+ T cells that express and secrete IL-17 can be produced in vitro and RA further contributes to stabilize this phenotype.
Thu Oct 21 00:00:00 EDT 2021
Epinephrine Production in Th17 Cells and Experimental Autoimmune Encephalitis.
Frontiers in immunology
Yang P,Tian H,Zou YR,Chambon P,Ichinose H,Honig G,Diamond B,Kim SJ
Published figure using CD4 monoclonal antibody (Product # 56-0041-82) in Flow Cytometry
Mon Jul 05 00:00:00 EDT 2021
Antagonistic Inflammatory Phenotypes Dictate Tumor Fate and Response to Immune Checkpoint Blockade.
Immunity
Bonavita E,Bromley CP,Jonsson G,Pelly VS,Sahoo S,Walwyn-Brown K,Mensurado S,Moeini A,Flanagan E,Bell CR,Chiang SC,Chikkanna-Gowda CP,Rogers N,Silva-Santos B,Jaillon S,Mantovani A,Reis e Sousa C,Guerra N,Davis DM,Zelenay S
Published figure using CD4 monoclonal antibody (Product # 56-0041-82) in Flow Cytometry
Tue Dec 15 00:00:00 EST 2020
Splenic Capture and In Vivo Intracellular Biodegradation of Biological-Grade Graphene Oxide Sheets.
ACS nano
Newman L,Jasim DA,Prestat E,Lozano N,de Lazaro I,Nam Y,Assas BM,Pennock J,Haigh SJ,Bussy C,Kostarelos K
Published figure using CD4 monoclonal antibody (Product # 56-0041-82) in Flow Cytometry
Tue Aug 25 00:00:00 EDT 2020
Deregulated Notch and Wnt signaling activates early-stage myeloid regeneration pathways in leukemia.
The Journal of experimental medicine
Kang YA,Pietras EM,Passegué E
Published figure using CD4 monoclonal antibody (Product # 56-0041-82) in Flow Cytometry
Mon Mar 02 00:00:00 EST 2020
Runx proteins mediate protective immunity against Leishmania donovani infection by promoting CD40 expression on dendritic cells.
PLoS pathogens
Akhtar MN,Mishra M,Yadav V,Yadav M,Gujar R,Lal S,Kumar R,Khatri N,Sen P
Published figure using CD4 monoclonal antibody (Product # 56-0041-82) in Flow Cytometry
Tue Dec 01 00:00:00 EST 2020
NLRX1 is a key regulator of immune signaling during invasive pulmonary aspergillosis.
PLoS pathogens
Kastelberg B,Tubau-Juni N,Ayubi T,Leung A,Leber A,Hontecillas R,Bassaganya-Riera J,Kale SD
56-0041 was used in Flow cytometry/Cell sorting to point strongly towards the cell-specific and contextual function of Nlrx1 during invasive pulmonary aspergillosis and may lead to novel therapeutics to reduce Th2 responses by CD103+ DCs or heightened recruitment of neutrophils.
Tue Sep 01 00:00:00 EDT 2020
DEK-targeting aptamer DTA-64 attenuates bronchial EMT-mediated airway remodelling by suppressing TGF-β1/Smad, MAPK and PI3K signalling pathway in asthma.
Journal of cellular and molecular medicine
Song Y,Wang Z,Jiang J,Piao Y,Li L,Xu C,Piao H,Li L,Yan G
Published figure using CD4 monoclonal antibody (Product # 56-0041-82) in Flow Cytometry
Tue Dec 01 00:00:00 EST 2020
Enhanced alleviation of aGVHD by TGF-β1-modified mesenchymal stem cells in mice through shifting MΦ into M2 phenotype and promoting the differentiation of Treg cells.
Journal of cellular and molecular medicine
Wu R,Liu C,Deng X,Chen L,Hao S,Ma L
Published figure using CD4 monoclonal antibody (Product # 56-0041-82) in Flow Cytometry
Wed Jan 01 00:00:00 EST 2020
HDAC Inhibitor, CG-745, Enhances the Anti-Cancer Effect of Anti-PD-1 Immune Checkpoint Inhibitor by Modulation of the Immune Microenvironment.
Journal of Cancer
Kim YD,Park SM,Ha HC,Lee AR,Won H,Cha H,Cho S,Cho JM
Published figure using CD4 monoclonal antibody (Product # 56-0041-82) in Flow Cytometry
Mon Sep 28 00:00:00 EDT 2020
Effects of combined treatment with PD‑L1 Ig and CD40L mAb on immune tolerance in the CBA/J x DBA/2 mouse model.
Molecular medicine reports
Li G,Yang L,Li D,Zhang J,Du L,Xia L,Liu Y,Hu W
Published figure using CD4 monoclonal antibody (Product # 56-0041-82) in Flow Cytometry
Wed Apr 01 00:00:00 EDT 2020
FUT1 deficiency elicits immune dysregulation and corneal opacity in steady state and under stress.
Cell death & disease
Kim KW,Ryu JS,Ko JH,Kim JY,Kim HJ,Lee HJ,Oh JH,Chung JH,Oh JY
Published figure using CD4 monoclonal antibody (Product # 56-0041-82) in Flow Cytometry
Fri Apr 24 00:00:00 EDT 2020
Elevated granulocytic myeloid-derived suppressor cells are closely related with elevation of Th17 cells in mice with experimental asthma.
International journal of biological sciences
Xue F,Yu M,Li L,Zhang W,Ma Y,Dong L,Shan W,Zheng Y,Wang T,Feng D,Lv J,Wang X
Published figure using CD4 monoclonal antibody (Product # 56-0041-82) in Flow Cytometry
Fri Nov 12 00:00:00 EST 2021
Comparative Analysis of Age-Related Changes in Lacrimal Glands and Meibomian Glands of a C57BL/6 Male Mouse Model.
International journal of molecular sciences
Yoon CH,Ryu JS,Hwang HS,Kim MK
Published figure using CD4 monoclonal antibody (Product # 56-0041-82) in Flow Cytometry
Thu Jun 11 00:00:00 EDT 2020
Truncated PPM1D Prevents Apoptosis in the Murine Thymus and Promotes Ionizing Radiation-Induced Lymphoma.
Cells
Martinikova AS,Burocziova M,Stoyanov M,Macurek L
Published figure using CD4 monoclonal antibody (Product # 56-0041-82) in Flow Cytometry
Thu Sep 10 00:00:00 EDT 2020
Artificial Mini Dendritic Cells Boost T Cell-Based Immunotherapy for Ovarian Cancer.
Advanced science (Weinheim, Baden-Wurttemberg, Germany)
Cheng S,Xu C,Jin Y,Li Y,Zhong C,Ma J,Yang J,Zhang N,Li Y,Wang C,Yang Z,Wang Y
Published figure using CD4 monoclonal antibody (Product # 56-0041-82) in Flow Cytometry
Wed Apr 01 00:00:00 EDT 2020
Ovarian granulosa cell tumor characterization identifies FOXL2 as an immunotherapeutic target.
JCI insight
Pierini S,Tanyi JL,Simpkins F,George E,Uribe-Herranz M,Drapkin R,Burger R,Morgan MA,Facciabene A
Published figure using CD4 monoclonal antibody (Product # 56-0041-82) in Flow Cytometry
Thu Aug 20 00:00:00 EDT 2020
Tankyrase inhibition sensitizes melanoma to PD-1 immune checkpoint blockade in syngeneic mouse models.
Communications biology
Waaler J,Mygland L,Tveita A,Strand MF,Solberg NT,Olsen PA,Aizenshtadt A,Fauskanger M,Lund K,Brinch SA,Lycke M,Dybing E,Nygaard V,Bøe SL,Heintz KM,Hovig E,Hammarström C,Corthay A,Krauss S
Published figure using CD4 monoclonal antibody (Product # 56-0041-82) in Flow Cytometry
Fri Apr 24 00:00:00 EDT 2020
The Proteomic Landscape of Resting and Activated CD4+ T Cells Reveal Insights into Cell Differentiation and Function.
International journal of molecular sciences
Subbannayya Y,Haug M,Pinto SM,Mohanty V,Meås HZ,Flo TH,Prasad TSK,Kandasamy RK
Published figure using CD4 monoclonal antibody (Product # 56-0041-82) in Flow Cytometry
Tue Dec 29 00:00:00 EST 2020
The Proteomic Landscape of Resting and Activated CD4+ T Cells Reveal Insights into Cell Differentiation and Function.
International journal of molecular sciences
Subbannayya Y,Haug M,Pinto SM,Mohanty V,Meås HZ,Flo TH,Prasad TSK,Kandasamy RK
Published figure using CD4 monoclonal antibody (Product # 56-0041-82) in Flow Cytometry
Tue Dec 29 00:00:00 EST 2020
Salt Sensing by Serum/Glucocorticoid-Regulated Kinase 1 Promotes Th17-like Inflammatory Adaptation of Foxp3+ Regulatory T Cells.
Cell reports
Yang YH,Istomine R,Alvarez F,Al-Aubodah TA,Shi XQ,Takano T,Thornton AM,Shevach EM,Zhang J,Piccirillo CA
56-0041-82 was used in Flow Cytometry to show that high salt (HS) drives thymic Treg cells to adopt a T helper type 17 (Th17)-like phenotype and enhances generation of Th17-like induced Treg cells in a SGK1-dependent manner, all the while maintaining suppressive function.
Tue Feb 04 00:00:00 EST 2020
CD103+ cDC1 and endogenous CD8+ T cells are necessary for improved CD40L-overexpressing CAR T cell antitumor function.
Nature communications
Kuhn NF,Lopez AV,Li X,Cai W,Daniyan AF,Brentjens RJ
56-0041 was used in Flow cytometry/Cell sorting to demonstrate the stimulatory effect of CD40L-overexpressing CAR T cells on innate and adaptive immune cells, and provide a rationale for using CD40L-overexpressing CAR T cells to improve immunotherapy responses.
Wed Dec 02 00:00:00 EST 2020
ICOS agonism by JTX-2011 (vopratelimab) requires initial T cell priming and Fc cross-linking for optimal T cell activation and anti-tumor immunity in preclinical models.
PloS one
Hanson A,Elpek K,Duong E,Shallberg L,Fan M,Johnson C,Wallace M,Mabry GR,Sazinsky S,Pepper L,Shu CJ,Sathyanarayanan S,Zuerndorfer S,Simpson T,Gostissa M,Briskin M,Law D,Michaelson J,Harvey CJ
Published figure using CD4 monoclonal antibody (Product # 56-0041-82) in Flow Cytometry
Mon Nov 16 00:00:00 EST 2020
Tregitopes regulate the tolerogenic immune response and decrease the foetal death rate in abortion-prone mouse matings.
Scientific reports
Kedzierska AE,Lorek D,Slawek A,Chelmonska-Soyta A
56-0041-82 was used in Flow Cytometry to indicate a potential alternative to IVIg for therapeutic intervention in case of pregnancy failures.
Mon Jun 29 00:00:00 EDT 2020
Tregitopes regulate the tolerogenic immune response and decrease the foetal death rate in abortion-prone mouse matings.
Scientific reports
Kedzierska AE,Lorek D,Slawek A,Chelmonska-Soyta A
56-0041-82 was used in Flow Cytometry to indicate a potential alternative to IVIg for therapeutic intervention in case of pregnancy failures.
Mon Jun 29 00:00:00 EDT 2020
Bixin Attenuates Experimental Autoimmune Encephalomyelitis by Suppressing TXNIP/NLRP3 Inflammasome Activity and Activating NRF2 Signaling.
Frontiers in immunology
Yu Y,Wu DM,Li J,Deng SH,Liu T,Zhang T,He M,Zhao YY,Xu Y
Published figure using CD4 monoclonal antibody (Product # 56-0041-82) in Flow Cytometry
Mon Jun 21 00:00:00 EDT 2021
Long-term ex vivo haematopoietic-stem-cell expansion allows nonconditioned transplantation.
Nature
Wilkinson AC,Ishida R,Kikuchi M,Sudo K,Morita M,Crisostomo RV,Yamamoto R,Loh KM,Nakamura Y,Watanabe M,Nakauchi H,Yamazaki S
Published figure using CD4 monoclonal antibody (Product # 56-0041-82) in Flow Cytometry
Mon Jul 01 00:00:00 EDT 2019
Characterization of immune cell subtypes in three commonly used mouse strains reveals gender and strain-specific variations.
Laboratory investigation; a journal of technical methods and pathology
Hensel JA,Khattar V,Ashton R,Ponnazhagan S
Published figure using CD4 monoclonal antibody (Product # 56-0041-82) in Flow Cytometry
Tue Jan 01 00:00:00 EST 2019
Bryostatin-1 ameliorated experimental colitis in Il-10-/- Mice by protecting the intestinal barrier and limiting immune dysfunction.
Journal of cellular and molecular medicine
Zuo L,Li J,Ge S,Ge Y,Shen M,Wang Y,Zhou C,Wu R,Hu J
Published figure using CD4 monoclonal antibody (Product # 56-0041-82) in Flow Cytometry
Thu Aug 01 00:00:00 EDT 2019
Lactobacillus rhamnosus GG attenuates tenofovir disoproxil fumarate-induced bone loss in male mice via gut-microbiota-dependent anti-inflammation.
Therapeutic advances in chronic disease
Liu H,Gu R,Li W,Zhou W,Cong Z,Xue J,Liu Y,Wei Q,Zhou Y
Published figure using CD4 monoclonal antibody (Product # 56-0041-82) in Flow Cytometry
Sat Apr 09 00:00:00 EDT 2022
Interleukin 10 Gene-Modified Bone Marrow-Derived Dendritic Cells Attenuate Liver Fibrosis in Mice by Inducing Regulatory T Cells and Inhibiting the TGF-β/Smad Signaling Pathway.
Mediators of inflammation
Xu Y,Tang X,Yang M,Zhang S,Li S,Chen Y,Liu M,Guo Y,Lu M
Published figure using CD4 monoclonal antibody (Product # 56-0041-82) in Flow Cytometry
Tue Jun 11 00:00:00 EDT 2019
IL-31 plays dual roles in lung inflammation in an OVA-induced murine asthma model.
Biology open
Huang J,Yue H,Jiang T,Gao J,Shi Y,Shi B,Wu X,Gou X
Published figure using CD4 monoclonal antibody (Product # 56-0041-82) in Flow Cytometry
Tue Jan 15 00:00:00 EST 2019
Antitumor and immunomodulatory effects of a novel multitarget inhibitor, CS2164, in mouse hepatocellular carcinoma models.
Anti-cancer drugs
Zhou Y,Fu C,Kong Y,Pan D,Wang Y,Huang S,Li Z,Ning Z,Lu X,Shan S,Xin L
Published figure using CD4 monoclonal antibody (Product # 56-0041-82) in Flow Cytometry
Tue Oct 01 00:00:00 EDT 2019
Epithelial EP4 plays an essential role in maintaining homeostasis in colon.
Scientific reports
Matsumoto Y,Nakanishi Y,Yoshioka T,Yamaga Y,Masuda T,Fukunaga Y,Sono M,Yoshikawa T,Nagao M,Araki O,Ogawa S,Goto N,Hiramatsu Y,Breyer RM,Fukuda A,Seno H
Published figure using CD4 monoclonal antibody (Product # 56-0041-82) in Immunohistochemistry
Wed Oct 23 00:00:00 EDT 2019
An attenuated Zika virus NS4B protein mutant is a potent inducer of antiviral immune responses.
NPJ vaccines
Li G,Adam A,Luo H,Shan C,Cao Z,Fontes-Garfias CR,Sarathy VV,Teleki C,Winkelmann ER,Liang Y,Sun J,Bourne N,Barrett ADT,Shi PY,Wang T
Published figure using CD4 monoclonal antibody (Product # 56-0041-82) in Flow Cytometry
Thu Oct 01 00:00:00 EDT 2020
Next Generation Sequencing for Long Non-coding RNAs Profile for CD4+ T Cells in the Mouse Model of Acute Asthma.
Frontiers in genetics
Wang Z,Ji N,Chen Z,Wu C,Sun Z,Yu W,Hu F,Huang M,Zhang M
Published figure using CD4 monoclonal antibody (Product # 56-0041-82) in Flow Cytometry
Fri Apr 08 00:00:00 EDT 2022
Sex Differences in Mouse Popliteal Lymph Nodes.
Scientific reports
Dill-Garlow R,Chen KE,Walker AM
Published figure using CD4 monoclonal antibody (Product # 56-0041-82) in Flow Cytometry
Wed Jan 30 00:00:00 EST 2019
TLR1/2 Specific Small-Molecule Agonist Suppresses Leukemia Cancer Cell Growth by Stimulating Cytotoxic T Lymphocytes.
Advanced science (Weinheim, Baden-Wurttemberg, Germany)
Cen X,Zhu G,Yang J,Yang J,Guo J,Jin J,Nandakumar KS,Yang W,Yin H,Liu S,Cheng K
Published figure using CD4 monoclonal antibody (Product # 56-0041-82) in Flow Cytometry
Fri May 17 00:00:00 EDT 2019
Molecular Profiling and Functional Analysis of Macrophage-Derived Tumor Extracellular Vesicles.
Cell reports
Cianciaruso C,Beltraminelli T,Duval F,Nassiri S,Hamelin R,Mozes A,Gallart-Ayala H,Ceada Torres G,Torchia B,Ries CH,Ivanisevic J,De Palma M
Published figure using CD4 monoclonal antibody (Product # 56-0041-82) in Flow Cytometry
Tue Jun 04 00:00:00 EDT 2019
Tissue-Restricted Adaptive Type 2 Immunity Is Orchestrated by Expression of the Costimulatory Molecule OX40L on Group 2 Innate Lymphoid Cells.
Immunity
Halim TYF,Rana BMJ,Walker JA,Kerscher B,Knolle MD,Jolin HE,Serrao EM,Haim-Vilmovsky L,Teichmann SA,Rodewald HR,Botto M,Vyse TJ,Fallon PG,Li Z,Withers DR,McKenzie ANJ
Published figure using CD4 monoclonal antibody (Product # 56-0041-82) in Flow Cytometry
Tue Jun 19 00:00:00 EDT 2018
Nox2 in regulatory T cells promotes angiotensin II-induced cardiovascular remodeling.
The Journal of clinical investigation
Emmerson A,Trevelin SC,Mongue-Din H,Becker PD,Ortiz C,Smyth LA,Peng Q,Elgueta R,Sawyer G,Ivetic A,Lechler RI,Lombardi G,Shah AM
Published figure using CD4 monoclonal antibody (Product # 56-0041-82) in Flow Cytometry
Mon Jul 02 00:00:00 EDT 2018
Pre-existing Immunity to Oncolytic Virus Potentiates Its Immunotherapeutic Efficacy.
Molecular therapy : the journal of the American Society of Gene Therapy
Ricca JM,Oseledchyk A,Walther T,Liu C,Mangarin L,Merghoub T,Wolchok JD,Zamarin D
Published figure using CD4 monoclonal antibody (Product # 56-0041-82) in Flow Cytometry
Wed Apr 04 00:00:00 EDT 2018
MicroRNA-126 deficiency enhanced the activation and function of CD4+ T cells by elevating IRS-1 pathway.
Clinical and experimental immunology
Chu F,Hu Y,Zhou Y,Guo M,Lu J,Zheng W,Xu H,Zhao J,Xu L
Published figure using CD4 monoclonal antibody (Product # 56-0041-82) in Flow Cytometry
Thu Feb 01 00:00:00 EST 2018
Impact of hyperglycemia on autoimmune pancreatitis and regulatory T-cells.
World journal of gastroenterology
Müller-Graff FT,Fitzner B,Jaster R,Vollmar B,Zechner D
Published figure using CD4 monoclonal antibody (Product # 56-0041-82) in Flow Cytometry
Sat Jul 28 00:00:00 EDT 2018
Baicalin Downregulates RLRs Signaling Pathway to Control Influenza A Virus Infection and Improve the Prognosis.
Evidence-based complementary and alternative medicine : eCAM
Pang P,Zheng K,Wu S,Xu H,Deng L,Shi Y,Chen X
Published figure using CD4 monoclonal antibody (Product # 56-0041-82) in Flow Cytometry
Thu Oct 01 00:00:00 EDT 2020
Sipa1 deficiency unleashes a host-immune mechanism eradicating chronic myelogenous leukemia-initiating cells.
Nature communications
Xu Y,Ikeda S,Sumida K,Yamamoto R,Tanaka H,Minato N
Published figure using CD4 monoclonal antibody (Product # 56-0041-82) in Flow Cytometry
Fri Mar 02 00:00:00 EST 2018
Pyruvate dehydrogenase complex stimulation promotes immunometabolic homeostasis and sepsis survival.
JCI insight
McCall CE,Zabalawi M,Liu T,Martin A,Long DL,Buechler NL,Arts RJW,Netea M,Yoza BK,Stacpoole PW,Vachharajani V
Published figure using CD4 monoclonal antibody (Product # 56-0041-82) in Flow Cytometry
Thu Aug 09 00:00:00 EDT 2018
Glutathione de novo synthesis but not recycling process coordinates with glutamine catabolism to control redox homeostasis and directs murine T cell differentiation.
eLife
Lian G,Gnanaprakasam JR,Wang T,Wu R,Chen X,Liu L,Shen Y,Yang M,Yang J,Chen Y,Vasiliou V,Cassel TA,Green DR,Liu Y,Fan TW,Wang R
Published figure using CD4 monoclonal antibody (Product # 56-0041-82) in Flow Cytometry
Mon Sep 10 00:00:00 EDT 2018
A cancer vaccine-mediated postoperative immunotherapy for recurrent and metastatic tumors.
Nature communications
Wang T,Wang D,Yu H,Feng B,Zhou F,Zhang H,Zhou L,Jiao S,Li Y
Published figure using CD4 monoclonal antibody (Product # 56-0041-82) in Flow Cytometry
Wed Apr 18 00:00:00 EDT 2018
Photosensitizer Micelles Together with IDO Inhibitor Enhance Cancer Photothermal Therapy and Immunotherapy.
Advanced science (Weinheim, Baden-Wurttemberg, Germany)
Peng J,Xiao Y,Li W,Yang Q,Tan L,Jia Y,Qu Y,Qian Z
Published figure using CD4 monoclonal antibody (Product # 56-0041-82) in Flow Cytometry
Tue May 01 00:00:00 EDT 2018
A stochastic epigenetic switch controls the dynamics of T-cell lineage commitment.
eLife
Ng KK,Yui MA,Mehta A,Siu S,Irwin B,Pease S,Hirose S,Elowitz MB,Rothenberg EV,Kueh HY
Published figure using CD4 monoclonal antibody (Product # 56-0041-82) in Flow Cytometry
Tue Nov 20 00:00:00 EST 2018
Microglia prevent peripheral immune cell invasion and promote an anti-inflammatory environment in the brain of APP-PS1 transgenic mice.
Journal of neuroinflammation
Unger MS,Schernthaner P,Marschallinger J,Mrowetz H,Aigner L
Published figure using CD4 monoclonal antibody (Product # 56-0041-82) in Flow Cytometry
Fri Sep 21 00:00:00 EDT 2018
Macrophage Depletion Protects against Cigarette Smoke-Induced Inflammatory Response in the Mouse Colon and Lung.
Frontiers in physiology
Lim D,Kim W,Lee C,Bae H,Kim J
Published figure using CD4 monoclonal antibody (Product # 56-0041-82) in Flow Cytometry
Wed Sep 30 00:00:00 EDT 2020
Plasmodium co-infection protects against chikungunya virus-induced pathologies.
Nature communications
Teo TH,Lum FM,Ghaffar K,Chan YH,Amrun SN,Tan JJL,Lee CYP,Chua TK,Carissimo G,Lee WWL,Claser C,Rajarethinam R,Rénia L,Ng LFP
Published figure using CD4 monoclonal antibody (Product # 56-0041-82) in Flow Cytometry
Tue Sep 25 00:00:00 EDT 2018
Apigenin suppresses PD-L1 expression in melanoma and host dendritic cells to elicit synergistic therapeutic effects.
Journal of experimental & clinical cancer research : CR
Xu L,Zhang Y,Tian K,Chen X,Zhang R,Mu X,Wu Y,Wang D,Wang S,Liu F,Wang T,Zhang J,Liu S,Zhang Y,Tu C,Liu H
Published figure using CD4 monoclonal antibody (Product # 56-0041-82) in Flow Cytometry
Mon Oct 29 00:00:00 EDT 2018
Microbiota Reconstitution Does Not Cause Bone Loss in Germ-Free Mice.
mSphere
Quach D,Collins F,Parameswaran N,McCabe L,Britton RA
Published figure using CD4 monoclonal antibody (Product # 56-0041-82) in Flow Cytometry
Wed Nov 20 00:00:00 EST 2019
Store-Operated Ca2+ Entry Controls Clonal Expansion of T Cells through Metabolic Reprogramming.
Immunity
Vaeth M,Maus M,Klein-Hessling S,Freinkman E,Yang J,Eckstein M,Cameron S,Turvey SE,Serfling E,Berberich-Siebelt F,Possemato R,Feske S
Published figure using CD4 monoclonal antibody (Product # 56-0041-82) in Flow Cytometry
Tue Oct 17 00:00:00 EDT 2017
A CCR4 antagonist reverses the tumor-promoting microenvironment of renal cancer.
The Journal of clinical investigation
Berlato C,Khan MN,Schioppa T,Thompson R,Maniati E,Montfort A,Jangani M,Canosa M,Kulbe H,Hagemann UB,Duncan AR,Fletcher L,Wilkinson RW,Powles T,Quezada SA,Balkwill FR
Published figure using CD4 monoclonal antibody (Product # 56-0041-82) in Flow Cytometry
Wed Mar 01 00:00:00 EST 2017
Egr2 and 3 control adaptive immune responses by temporally uncoupling expansion from T cell differentiation.
The Journal of experimental medicine
Miao T,Symonds ALJ,Singh R,Symonds JD,Ogbe A,Omodho B,Zhu B,Li S,Wang P
Published figure using CD4 monoclonal antibody (Product # 56-0041-82) in Flow Cytometry
Mon Jun 05 00:00:00 EDT 2017
Oncolytic Adenovirus and Tumor-Targeting Immune Modulatory Therapy Improve Autologous Cancer Vaccination.
Cancer research
Jiang H,Rivera-Molina Y,Gomez-Manzano C,Clise-Dwyer K,Bover L,Vence LM,Yuan Y,Lang FF,Toniatti C,Hossain MB,Fueyo J
Published figure using CD4 monoclonal antibody (Product # 56-0041-82) in Flow Cytometry
Sat Jul 15 00:00:00 EDT 2017
CD40-mediated signalling influences trafficking, T-cell receptor expression, and T-cell pathogenesis, in the NOD model of type 1 diabetes.
Immunology
Vaitaitis GM,Waid DM,Yussman MG,Wagner DH
56-0041 was used in Flow cytometry/Cell sorting to determine the mechanism by which CD40 results in the pathogenesis of type 1 diabetes.
Sun Oct 01 00:00:00 EDT 2017
Betulin from Hedyotis hedyotidea ameliorates concanavalin A-induced and T cell-mediated autoimmune hepatitis in mice.
Acta pharmacologica Sinica
Zhou YQ,Weng XF,Dou R,Tan XS,Zhang TT,Fang JB,Wu XW
Published figure using CD4 monoclonal antibody (Product # 56-0041-82) in Flow Cytometry
Wed Feb 01 00:00:00 EST 2017
Cornea lymphatics drive the CD8+ T-cell response to herpes simplex virus-1.
Immunology and cell biology
Gurung HR,Carr MM,Carr DJ
Published figure using CD4 monoclonal antibody (Product # 56-0041-82) in Flow Cytometry
Sun Jan 01 00:00:00 EST 2017
ADAR1 deletion induces NFκB and interferon signaling dependent liver inflammation and fibrosis.
RNA biology
Ben-Shoshan SO,Kagan P,Sultan M,Barabash Z,Dor C,Jacob-Hirsch J,Harmelin A,Pappo O,Marcu-Malina V,Ben-Ari Z,Amariglio N,Rechavi G,Goldstein I,Safran M
Published figure using CD4 monoclonal antibody (Product # 56-0041-82) in Flow Cytometry
Thu May 04 00:00:00 EDT 2017
Adeno-associated virus serotype rh.10 displays strong muscle tropism following intraperitoneal delivery.
Scientific reports
Ai J,Li J,Gessler DJ,Su Q,Wei Q,Li H,Gao G
Published figure using CD4 monoclonal antibody (Product # 56-0041-82) in Immunofluorescence
Mon Jan 09 00:00:00 EST 2017
Shifts in the Gut Microbiota Composition Due to Depleted Bone Marrow Beta Adrenergic Signaling Are Associated with Suppressed Inflammatory Transcriptional Networks in the Mouse Colon.
Frontiers in physiology
Yang T,Ahmari N,Schmidt JT,Redler T,Arocha R,Pacholec K,Magee KL,Malphurs W,Owen JL,Krane GA,Li E,Wang GP,Vickroy TW,Raizada MK,Martyniuk CJ,Zubcevic J
Published figure using CD4 monoclonal antibody (Product # 56-0041-82) in Immunofluorescence
Thu Oct 01 00:00:00 EDT 2020
Heavy Chain-Hyaluronan/Pentraxin 3 from Amniotic Membrane Suppresses Inflammation and Scarring in Murine Lacrimal Gland and Conjunctiva of Chronic Graft-versus-Host Disease.
Scientific reports
Ogawa Y,He H,Mukai S,Imada T,Nakamura S,Su CW,Mahabole M,Tseng SC,Tsubota K
Published figure using CD4 monoclonal antibody (Product # 56-0041-82) in Immunohistochemistry
Mon Feb 06 00:00:00 EST 2017
Location of tumor affects local and distant immune cell type and number.
Immunity, inflammation and disease
Hensel JA,Khattar V,Ashton R,Lee C,Siegal GP,Ponnazhagan S
Published figure using CD4 monoclonal antibody (Product # 56-0041-82) in Flow Cytometry
Wed Mar 01 00:00:00 EST 2017
Human amnion cells reverse acute and chronic pulmonary damage in experimental neonatal lung injury.
Stem cell research & therapy
Zhu D,Tan J,Maleken AS,Muljadi R,Chan ST,Lau SN,Elgass K,Leaw B,Mockler J,Chambers D,Leeman KT,Kim CF,Wallace EM,Lim R
Published figure using CD4 monoclonal antibody (Product # 56-0041-82) in Flow Cytometry
Fri Nov 10 00:00:00 EST 2017
MSC-derived Extracellular Vesicles Attenuate Immune Responses in Two Autoimmune Murine Models: Type 1 Diabetes and Uveoretinitis.
Stem cell reports
Shigemoto-Kuroda T,Oh JY,Kim DK,Jeong HJ,Park SY,Lee HJ,Park JW,Kim TW,An SY,Prockop DJ,Lee RH
Published figure using CD4 monoclonal antibody (Product # 56-0041-82) in Flow Cytometry
Tue May 09 00:00:00 EDT 2017
Traditional Herbal Medicine-Derived Sulforaphene LFS-01 Reverses Colitis in Mice by Selectively Altering the Gut Microbiota and Promoting Intestinal Gamma-Delta T Cells.
Frontiers in pharmacology
Li M,Gao J,Tang Y,Liu M,Wu S,Qu K,Long X,Li H,Liu M,Liu Y,Yuan J,Mao L,Liu Y,Zheng X,Wang E,Wang J,Yang Y
Published figure using CD4 monoclonal antibody (Product # 56-0041-82) in Flow Cytometry
Wed Sep 30 00:00:00 EDT 2020
Rottlerin as a therapeutic approach in psoriasis: Evidence from in vitro and in vivo studies.
PloS one
Min M,Yan BX,Wang P,Landeck L,Chen JQ,Li W,Cai SQ,Zheng M,Man XY
Published figure using CD4 monoclonal antibody (Product # 56-0041-82) in Flow Cytometry
Tue Jan 16 00:00:00 EST 2018
Compensatory upregulation of PD-1, LAG-3, and CTLA-4 limits the efficacy of single-agent checkpoint blockade in metastatic ovarian cancer.
Oncoimmunology
Huang RY,Francois A,McGray AR,Miliotto A,Odunsi K
Published figure using CD4 monoclonal antibody (Product # 56-0041-82) in Flow Cytometry
Tue Jan 12 00:00:00 EST 2021
Irgm1 coordinately regulates autoimmunity and host defense at select mucosal surfaces.
JCI insight
Azzam KM,Madenspacher JH,Cain DW,Lai L,Gowdy KM,Rai P,Janardhan K,Clayton N,Cunningham W,Jensen H,Patel PS,Kearney JF,Taylor GA,Fessler MB
Published figure using CD4 monoclonal antibody (Product # 56-0041-82) in Flow Cytometry
Thu Aug 17 00:00:00 EDT 2017
Intratumoral modulation of the inducible co-stimulator ICOS by recombinant oncolytic virus promotes systemic anti-tumour immunity.
Nature communications
Zamarin D,Holmgaard RB,Ricca J,Plitt T,Palese P,Sharma P,Merghoub T,Wolchok JD,Allison JP
Published figure using CD4 monoclonal antibody (Product # 56-0041-82) in Flow Cytometry
Mon Feb 13 00:00:00 EST 2017
A Multistage Subunit Vaccine Effectively Protects Mice Against Primary Progressive Tuberculosis, Latency and Reactivation.
EBioMedicine
Ma J,Teng X,Wang X,Fan X,Wu Y,Tian M,Zhou Z,Li L
Published figure using CD4 monoclonal antibody (Product # 56-0041-82) in Flow Cytometry
Tue Aug 01 00:00:00 EDT 2017
Host-Protozoan Interactions Protect from Mucosal Infections through Activation of the Inflammasome.
Cell
Chudnovskiy A,Mortha A,Kana V,Kennard A,Ramirez JD,Rahman A,Remark R,Mogno I,Ng R,Gnjatic S,Amir ED,Solovyov A,Greenbaum B,Clemente J,Faith J,Belkaid Y,Grigg ME,Merad M
Published figure using CD4 monoclonal antibody (Product # 56-0041-82) in Flow Cytometry
Thu Oct 06 00:00:00 EDT 2016
The Deubiquitinase OTULIN Is an Essential Negative Regulator of Inflammation and Autoimmunity.
Cell
Damgaard RB,Walker JA,Marco-Casanova P,Morgan NV,Titheradge HL,Elliott PR,McHale D,Maher ER,McKenzie ANJ,Komander D
56-0041 was used in Flow cytometry/Cell sorting to study how OTULIN may be critical in restraining life-threatening spontaneous inflammation and maintaining immune homeostasis.
Thu Aug 25 00:00:00 EDT 2016
Group 2 innate lymphoid cells license dendritic cells to potentiate memory TH2 cell responses.
Nature immunology
Halim TY,Hwang YY,Scanlon ST,Zaghouani H,Garbi N,Fallon PG,McKenzie AN
56-0041 was used in Flow cytometry/Cell sorting to investigate the role of ILC2 cells in allergic inflammation, showing that they license dendritic cells to potentiate memory TH2 cell responses.
Fri Jan 01 00:00:00 EST 2016
Foxp3 and Toll-like receptor signaling balance Treg cell anabolic metabolism for suppression.
Nature immunology
Gerriets VA,Kishton RJ,Johnson MO,Cohen S,Siska PJ,Nichols AG,Warmoes MO,de Cubas AA,MacIver NJ,Locasale JW,Turka LA,Wells AD,Rathmell JC
Published figure using CD4 monoclonal antibody (Product # 56-0041-82) in Flow Cytometry
Thu Dec 01 00:00:00 EST 2016
Macrophages transfer antigens to dendritic cells by releasing exosomes containing dead-cell-associated antigens partially through a ceramide-dependent pathway to enhance CD4(+) T-cell responses.
Immunology
Xu Y,Liu Y,Yang C,Kang L,Wang M,Hu J,He H,Song W,Tang H
Published figure using CD4 monoclonal antibody (Product # 56-0041-82) in Flow Cytometry
Sat Oct 01 00:00:00 EDT 2016
p(⁷⁰S⁶K¹) in the TORC1 pathway is essential for the differentiation of Th17 Cells, but not Th1, Th2, or Treg cells in mice.
European journal of immunology
Sasaki CY,Chen G,Munk R,Eitan E,Martindale J,Longo DL,Ghosh P
Published figure using CD4 monoclonal antibody (Product # 56-0041-82) in Flow Cytometry
Fri Jan 01 00:00:00 EST 2016
Multispectral Imaging of T and B Cells in Murine Spleen and Tumor.
Journal of immunology (Baltimore, Md. : 1950)
Feng Z,Jensen SM,Messenheimer DJ,Farhad M,Neuberger M,Bifulco CB,Fox BA
Published figure using CD4 monoclonal antibody (Product # 56-0041-82) in Immunofluorescence
Sun May 01 00:00:00 EDT 2016
Resident T Cells Are Unable To Control Herpes Simplex Virus-1 Activity in the Brain Ependymal Region during Latency.
Journal of immunology (Baltimore, Md. : 1950)
Menendez CM,Jinkins JK,Carr DJ
Published figure using CD4 monoclonal antibody (Product # 56-0041-82) in Flow Cytometry
Mon Aug 15 00:00:00 EDT 2016
Rapamycin ameliorates CCl4-induced liver fibrosis in mice through reciprocal regulation of the Th17/Treg cell balance.
Molecular medicine reports
Gu L,Deng WS,Sun XF,Zhou H,Xu Q
Published figure using CD4 monoclonal antibody (Product # 56-0041-82) in Flow Cytometry
Mon Aug 01 00:00:00 EDT 2016
PRDM14 promotes RAG-dependent Notch1 driver mutations in mouse T-ALL.
Biology open
Carofino BL,Ayanga B,Tracey LJ,Brooke-Bisschop T,Justice MJ
56-0041 was used in Flow cytometry/Cell sorting to investigate how PRDM14 promotes RAG-dependent Notch1 driver mutations in mouse T-ALL.
Sun May 15 00:00:00 EDT 2016
IL-15 superagonist/IL-15RαSushi-Fc fusion complex (IL-15SA/IL-15RαSu-Fc; ALT-803) markedly enhances specific subpopulations of NK and memory CD8+ T cells, and mediates potent anti-tumor activity against murine breast and colon carcinomas.
Oncotarget
Kim PS,Kwilas AR,Xu W,Alter S,Jeng EK,Wong HC,Schlom J,Hodge JW
56-0041 was used in Flow cytometry/Cell sorting to study the enhancement of subpopulations of NK and memory CD8+ T cells and mediation of potent anti-tumor activity against murine breast and colon carcinomas via the IL-15 superagonist/IL-15RalphaSushi-Fc fusion complex.
Tue Mar 29 00:00:00 EDT 2016
Lymphocyte Isolation, Th17 Cell Differentiation, Activation, and Staining.
Bio-protocol
Kumar P,Kolls JK
56-0041 was used in Flow cytometry/Cell sorting to describe the tools, reagents and procdedure for a Th17 cell differentiation method.
Mon Dec 05 00:00:00 EST 2016
Treg engage lymphotoxin beta receptor for afferent lymphatic transendothelial migration.
Nature communications
Brinkman CC,Iwami D,Hritzo MK,Xiong Y,Ahmad S,Simon T,Hippen KL,Blazar BR,Bromberg JS
Published figure using CD4 monoclonal antibody (Product # 56-0041-82) in Flow Cytometry
Tue Jun 21 00:00:00 EDT 2016
Stromal senescence establishes an immunosuppressive microenvironment that drives tumorigenesis.
Nature communications
Ruhland MK,Loza AJ,Capietto AH,Luo X,Knolhoff BL,Flanagan KC,Belt BA,Alspach E,Leahy K,Luo J,Schaffer A,Edwards JR,Longmore G,Faccio R,DeNardo DG,Stewart SA
Published figure using CD4 monoclonal antibody (Product # 56-0041-82) in Flow Cytometry
Wed Jun 08 00:00:00 EDT 2016
Interleukin-10 deficiency impairs regulatory T cell-derived neuropilin-1 functions and promotes Th1 and Th17 immunity.
Scientific reports
Wang S,Gao X,Shen G,Wang W,Li J,Zhao J,Wei YQ,Edwards CK
Published figure using CD4 monoclonal antibody (Product # 56-0041-82) in Flow Cytometry
Thu Apr 14 00:00:00 EDT 2016
NFATc1 supports imiquimod-induced skin inflammation by suppressing IL-10 synthesis in B cells.
Nature communications
Alrefai H,Muhammad K,Rudolf R,Pham DA,Klein-Hessling S,Patra AK,Avots A,Bukur V,Sahin U,Tenzer S,Goebeler M,Kerstan A,Serfling E
Published figure using CD4 monoclonal antibody (Product # 56-0041-82) in Flow Cytometry
Wed May 25 00:00:00 EDT 2016
Epigallocatechin-3-gallate (EGCG) inhibits imiquimod-induced psoriasis-like inflammation of BALB/c mice.
BMC complementary and alternative medicine
Zhang S,Liu X,Mei L,Wang H,Fang F
Published figure using CD4 monoclonal antibody (Product # 56-0041-82) in Flow Cytometry
Wed Aug 31 00:00:00 EDT 2016
Flagellin is a strong vaginal adjuvant of a therapeutic vaccine for genital cancer.
Oncoimmunology
Lee SE,Hong SH,Verma V,Lee YS,Duong TN,Jeong K,Uthaman S,Sung YC,Lee JT,Park IK,Min JJ,Rhee JH
Published figure using CD4 monoclonal antibody (Product # 56-0041-82) in Flow Cytometry
Mon Feb 01 00:00:00 EST 2016
A Diet Mimicking Fasting Promotes Regeneration and Reduces Autoimmunity and Multiple Sclerosis Symptoms.
Cell reports
Choi IY,Piccio L,Childress P,Bollman B,Ghosh A,Brandhorst S,Suarez J,Michalsen A,Cross AH,Morgan TE,Wei M,Paul F,Bock M,Longo VD
Published figure using CD4 monoclonal antibody (Product # 56-0041-82) in Flow Cytometry
Tue Jun 07 00:00:00 EDT 2016
TNF-Mediated Restriction of Arginase 1 Expression in Myeloid Cells Triggers Type 2 NO Synthase Activity at the Site of Infection.
Cell reports
Schleicher U,Paduch K,Debus A,Obermeyer S,König T,Kling JC,Ribechini E,Dudziak D,Mougiakakos D,Murray PJ,Ostuni R,Körner H,Bogdan C
Published figure using CD4 monoclonal antibody (Product # 56-0041-82) in Flow Cytometry
Tue May 03 00:00:00 EDT 2016
Diet-dependent, microbiota-independent regulation of IL-10-producing lamina propria macrophages in the small intestine.
Scientific reports
Ochi T,Feng Y,Kitamoto S,Nagao-Kitamoto H,Kuffa P,Atarashi K,Honda K,Teitelbaum DH,Kamada N
Published figure using CD4 monoclonal antibody (Product # 56-0041-82) in Flow Cytometry
Wed Jun 15 00:00:00 EDT 2016
CEACAM1 regulates TIM-3-mediated tolerance and exhaustion.
Nature
Huang YH,Zhu C,Kondo Y,Anderson AC,Gandhi A,Russell A,Dougan SK,Petersen BS,Melum E,Pertel T,Clayton KL,Raab M,Chen Q,Beauchemin N,Yazaki PJ,Pyzik M,Ostrowski MA,Glickman JN,Rudd CE,Ploegh HL,Franke A,Petsko GA,Kuchroo VK,Blumberg RS
Published figure using CD4 monoclonal antibody (Product # 56-0041-82) in Flow Cytometry
Thu Jan 15 00:00:00 EST 2015
Injectable, spontaneously assembling, inorganic scaffolds modulate immune cells in vivo and increase vaccine efficacy.
Nature biotechnology
Kim J,Li WA,Choi Y,Lewin SA,Verbeke CS,Dranoff G,Mooney DJ
Published figure using CD4 monoclonal antibody (Product # 56-0041-82) in Flow Cytometry
Thu Jan 01 00:00:00 EST 2015
Phosphatase Wip1 controls antigen-independent B-cell development in a p53-dependent manner.
Blood
Yi W,Hu X,Chen Z,Liu L,Tian Y,Chen H,Cong YS,Yang F,Zhang L,Rudolph KL,Zhang Z,Zhao Y,Ju Z
Published figure using CD4 monoclonal antibody (Product # 56-0041-82) in Flow Cytometry
Thu Jul 30 00:00:00 EDT 2015
IKKβ acts as a tumor suppressor in cancer-associated fibroblasts during intestinal tumorigenesis.
The Journal of experimental medicine
Pallangyo CK,Ziegler PK,Greten FR
Published figure using CD4 monoclonal antibody (Product # 56-0041-82) in Flow Cytometry
Mon Dec 14 00:00:00 EST 2015
Adaptive Immune Regulation of Mammary Postnatal Organogenesis.
Developmental cell
Plaks V,Boldajipour B,Linnemann JR,Nguyen NH,Kersten K,Wolf Y,Casbon AJ,Kong N,van den Bijgaart RJ,Sheppard D,Melton AC,Krummel MF,Werb Z
Published figure using CD4 monoclonal antibody (Product # 56-0041-82) in Flow Cytometry
Mon Sep 14 00:00:00 EDT 2015
Adaptive Immune Regulation of Mammary Postnatal Organogenesis.
Developmental cell
Plaks V,Boldajipour B,Linnemann JR,Nguyen NH,Kersten K,Wolf Y,Casbon AJ,Kong N,van den Bijgaart RJ,Sheppard D,Melton AC,Krummel MF,Werb Z
Published figure using CD4 monoclonal antibody (Product # 56-0041-82) in Flow Cytometry
Mon Sep 14 00:00:00 EDT 2015
B cell autophagy mediates TLR7-dependent autoimmunity and inflammation.
Autophagy
Weindel CG,Richey LJ,Bolland S,Mehta AJ,Kearney JF,Huber BT
Published figure using CD4 monoclonal antibody (Product # 56-0041-82) in Immunohistochemistry
Mon Apr 18 00:00:00 EDT 2016
IFN-γ ameliorates autoimmune encephalomyelitis by limiting myelin lipid peroxidation.
Proceedings of the National Academy of Sciences of the United States of America
Sosa RA,Murphey C,Robinson RR,Forsthuber TG
Published figure using CD4 monoclonal antibody (Product # 56-0041-82) in Immunofluorescence
Tue Sep 08 00:00:00 EDT 2015
Mitochondrial ATP transporter Ant2 depletion impairs erythropoiesis and B lymphopoiesis.
Cell death and differentiation
Cho J,Seo J,Lim CH,Yang L,Shiratsuchi T,Lee MH,Chowdhury RR,Kasahara H,Kim JS,Oh SP,Lee YJ,Terada N
Published figure using CD4 monoclonal antibody (Product # 56-0041-82) in Flow Cytometry
Tue Sep 01 00:00:00 EDT 2015
Mice lacking Axl and Mer tyrosine kinase receptors are susceptible to experimental autoimmune orchitis induction.
Immunology and cell biology
Li N,Liu Z,Zhang Y,Chen Q,Liu P,Cheng CY,Lee WM,Chen Y,Han D
Published figure using CD4 monoclonal antibody (Product # 56-0041-82) in Flow Cytometry
Sun Mar 01 00:00:00 EST 2015
B cell Rab7 mediates induction of activation-induced cytidine deaminase expression and class-switching in T-dependent and T-independent antibody responses.
Journal of immunology (Baltimore, Md. : 1950)
Pone EJ,Lam T,Lou Z,Wang R,Chen Y,Liu D,Edinger AL,Xu Z,Casali P
Published figure using CD4 monoclonal antibody (Product # 56-0041-82) in Flow Cytometry
Wed Apr 01 00:00:00 EDT 2015
VprBP Is Required for Efficient Editing and Selection of Igκ+ B Cells, but Is Dispensable for Igλ+ and Marginal Zone B Cell Maturation and Selection.
Journal of immunology (Baltimore, Md. : 1950)
Palmer VL,Aziz-Seible R,Kassmeier MD,Rothermund M,Perry GA,Swanson PC
56-0041 was used in Flow cytometry/Cell sorting to determine the contribution of the protein, VprBP, to B cell development and selection.
Sat Aug 15 00:00:00 EDT 2015
Histone deacetylation of memory T lymphocytes by You-Gui-Wan alleviates allergen-induced eosinophilic airway inflammation in asthma.
Chinese medicine
Zhang HP,Fu JJ,Fan T,Zhang WB,Wang ZL,Wang L,Wang G
Published figure using CD4 monoclonal antibody (Product # 56-0041-82) in Flow Cytometry
Mon Jun 15 00:00:00 EDT 2015
dNP2 is a blood-brain barrier-permeable peptide enabling ctCTLA-4 protein delivery to ameliorate experimental autoimmune encephalomyelitis.
Nature communications
Lim S,Kim WJ,Kim YH,Lee S,Koo JH,Lee JA,Yoon H,Kim DH,Park HJ,Kim HM,Lee HG,Yun Kim J,Lee JU,Hun Shin J,Kyun Kim L,Doh J,Kim H,Lee SK,Bothwell ALM,Suh M,Choi JM
Published figure using CD4 monoclonal antibody (Product # 56-0041-82) in Flow Cytometry
Tue Sep 15 00:00:00 EDT 2015
dNP2 is a blood-brain barrier-permeable peptide enabling ctCTLA-4 protein delivery to ameliorate experimental autoimmune encephalomyelitis.
Nature communications
Lim S,Kim WJ,Kim YH,Lee S,Koo JH,Lee JA,Yoon H,Kim DH,Park HJ,Kim HM,Lee HG,Yun Kim J,Lee JU,Hun Shin J,Kyun Kim L,Doh J,Kim H,Lee SK,Bothwell ALM,Suh M,Choi JM
Published figure using CD4 monoclonal antibody (Product # 56-0041-82) in Flow Cytometry
Tue Sep 15 00:00:00 EDT 2015
Mannan-modified adenovirus targeting TERT and VEGFR-2: A universal tumour vaccine.
Scientific reports
Wang Y,Zhang J,Wu Y,Ding ZY,Luo XM,Liu J,Zhong WN,Deng GH,Xia XY,Deng YT,Wei YQ,Jiang Y
Published figure using CD4 monoclonal antibody (Product # 56-0041-82) in Flow Cytometry
Thu Jun 18 00:00:00 EDT 2015
Intranasal Administration of Lentiviral miR-135a Regulates Mast Cell and Allergen-Induced Inflammation by Targeting GATA-3.
PloS one
Deng YQ,Yang YQ,Wang SB,Li F,Liu MZ,Hua QQ,Tao ZZ
Published figure using CD4 monoclonal antibody (Product # 56-0041-82) in Flow Cytometry
Tue May 31 00:00:00 EDT 2016
Interleukin-25 Mediates Transcriptional Control of PD-L1 via STAT3 in Multipotent Human Mesenchymal Stromal Cells (hMSCs) to Suppress Th17 Responses.
Stem cell reports
Wang WB,Yen ML,Liu KJ,Hsu PJ,Lin MH,Chen PM,Sudhir PR,Chen CH,Chen CH,Sytwu HK,Yen BL
Published figure using CD4 monoclonal antibody (Product # 56-0041-82) in Flow Cytometry
Tue Sep 08 00:00:00 EDT 2015
Immune targeting of the pleural space by intercostal approach.
BMC pulmonary medicine
Weber GF
56-0041 was used in Flow cytometry/Cell sorting to develop an experimental technique that allows for an in vivo analysis of pleural space immune cells participating in the host defense during airway disease.
Wed Feb 18 00:00:00 EST 2015
Rhinovirus-induced IL-25 in asthma exacerbation drives type 2 immunity and allergic pulmonary inflammation.
Science translational medicine
Beale J,Jayaraman A,Jackson DJ,Macintyre JDR,Edwards MR,Walton RP,Zhu J,Man Ching Y,Shamji B,Edwards M,Westwick J,Cousins DJ,Yi Hwang Y,McKenzie A,Johnston SL,Bartlett NW
56-0041 was used in Flow cytometry/Cell sorting to demonstrate asthmatic epithelial cells have an increased intrinsic capacity for expression of a pro-type 2 cytokine in response to a viral infection.
Wed Oct 01 00:00:00 EDT 2014
Pleural innate response activator B cells protect against pneumonia via a GM-CSF-IgM axis.
The Journal of experimental medicine
Weber GF,Chousterman BG,Hilgendorf I,Robbins CS,Theurl I,Gerhardt LM,Iwamoto Y,Quach TD,Ali M,Chen JW,Rothstein TL,Nahrendorf M,Weissleder R,Swirski FK
56-0041 was used in Flow cytometry/Cell sorting to study the migration and release of immunoglobulin M by B1a B cells in response to lung infection.
Mon Jun 02 00:00:00 EDT 2014
Autophagy regulates the therapeutic potential of mesenchymal stem cells in experimental autoimmune encephalomyelitis.
Autophagy
Dang S,Xu H,Xu C,Cai W,Li Q,Cheng Y,Jin M,Wang RX,Peng Y,Zhang Y,Wu C,He X,Wan B,Zhang Y
Published figure using CD4 monoclonal antibody (Product # 56-0041-82) in Flow Cytometry
Tue Jul 01 00:00:00 EDT 2014
Malaria-induced NLRP12/NLRP3-dependent caspase-1 activation mediates inflammation and hypersensitivity to bacterial superinfection.
PLoS pathogens
Ataide MA,Andrade WA,Zamboni DS,Wang D,Souza Mdo C,Franklin BS,Elian S,Martins FS,Pereira D,Reed G,Fitzgerald KA,Golenbock DT,Gazzinelli RT
Published figure using CD4 monoclonal antibody (Product # 56-0041-82) in Flow Cytometry
Wed Jan 01 00:00:00 EST 2014
Differential requirement for CCR4 and CCR7 during the development of innate and adaptive αβT cells in the adult thymus.
Journal of immunology (Baltimore, Md. : 1950)
Cowan JE,McCarthy NI,Parnell SM,White AJ,Bacon A,Serge A,Irla M,Lane PJ,Jenkinson EJ,Jenkinson WE,Anderson G
56-0041 was used in Flow cytometry/Cell sorting to identify novel roles for CCR7 during intrathymic T cell development, highlighting its importance in enabling multiple αβT cell lineages to access the thymic medulla.
Fri Aug 01 00:00:00 EDT 2014
Regulation of cyp26a1 on Th17 cells in mouse peri-implantation.
Journal of cellular and molecular medicine
Liu HY,Chao H,Liu ZK,Xia HF,Song Z,Yang Y,Peng JP
Published figure using CD4 monoclonal antibody (Product # 56-0041-82) in Flow Cytometry
Sat Mar 01 00:00:00 EST 2014
Nizatidine, a small molecular compound, enhances killed H5N1 vaccine cell-mediated responses and protects mice from lethal viral challenge.
Human vaccines & immunotherapeutics
Wang S,Wu B,Xue J,Wang M,Chen R,Wang B
Published figure using CD4 monoclonal antibody (Product # 56-0041-82) in Flow Cytometry
Mon Jan 05 00:00:00 EST 2015
High-dose interferon-γ promotes abortion in mice by suppressing Treg and Th17 polarization.
Journal of interferon & cytokine research : the official journal of the International Society for Interferon and Cytokine Research
Liu HY,Liu ZK,Chao H,Li Z,Song Z,Yang Y,Peng JP
Published figure using CD4 monoclonal antibody (Product # 56-0041-82) in Flow Cytometry
Thu May 01 00:00:00 EDT 2014
Somatostatin inhibits the production of interferon-γ by intestinal epithelial cells during intestinal ischemia-reperfusion in macaques.
Digestive diseases and sciences
Liu L,Tan Q,Hu B,Wu H,Wang C,Tang C
Published figure using CD4 monoclonal antibody (Product # 56-0041-82) in Immunohistochemistry
Wed Oct 01 00:00:00 EDT 2014
Cellular immunotherapy using irradiated lung cancer cell vaccine co-expressing GM-CSF and IL-18 can induce significant antitumor effects.
BMC cancer
Tian H,Shi G,Yang G,Zhang J,Li Y,Du T,Wang J,Xu F,Cheng L,Zhang X,Dai L,Chen X,Zhang S,Yang Y,Yu D,Wei Y,Deng H
Published figure using CD4 monoclonal antibody (Product # 56-0041-82) in Flow Cytometry
Wed Jan 29 00:00:00 EST 2014
Cellular immunotherapy using irradiated lung cancer cell vaccine co-expressing GM-CSF and IL-18 can induce significant antitumor effects.
BMC cancer
Tian H,Shi G,Yang G,Zhang J,Li Y,Du T,Wang J,Xu F,Cheng L,Zhang X,Dai L,Chen X,Zhang S,Yang Y,Yu D,Wei Y,Deng H
Published figure using CD4 monoclonal antibody (Product # 56-0041-82) in Flow Cytometry
Wed Jan 29 00:00:00 EST 2014
A chitin-like component on sclerotic cells of Fonsecaea pedrosoi inhibits Dectin-1-mediated murine Th17 development by masking β-glucans.
PloS one
Dong B,Li D,Li R,Chen SC,Liu W,Liu W,Chen L,Chen Y,Zhang X,Tong Z,Xia Y,Xia P,Wang Y,Duan Y
Published figure using CD4 monoclonal antibody (Product # 56-0041-82) in Flow Cytometry
Mon Sep 28 00:00:00 EDT 2015
Sequential transcriptional changes dictate safe and effective antigen-specific immunotherapy.
Nature communications
Burton BR,Britton GJ,Fang H,Verhagen J,Smithers B,Sabatos-Peyton CA,Carney LJ,Gough J,Strobel S,Wraith DC
56-0041 was used in Flow cytometry/Cell sorting to study the markers significant for antigen-specific immunotherapy such as regulatory CD4(+) T-cell transcription factors.
Wed Sep 03 00:00:00 EDT 2014
The thymic medulla is required for Foxp3+ regulatory but not conventional CD4+ thymocyte development.
The Journal of experimental medicine
Cowan JE,Parnell SM,Nakamura K,Caamano JH,Lane PJ,Jenkinson EJ,Jenkinson WE,Anderson G
56-0041 was used in Flow cytometry/Cell sorting to demonstrate a differential requirement for the thymic medulla in relation to CD4 conventional and Foxp3(+) thymocyte lineages.
Mon Apr 08 00:00:00 EDT 2013
Cbx4 regulates the proliferation of thymic epithelial cells and thymus function.
Development (Cambridge, England)
Liu B,Liu YF,Du YR,Mardaryev AN,Yang W,Chen H,Xu ZM,Xu CQ,Zhang XR,Botchkarev VA,Zhang Y,Xu GL
Published figure using CD4 monoclonal antibody (Product # 56-0041-82) in Flow Cytometry
Fri Feb 01 00:00:00 EST 2013
Tumor-specific CD4+ T cells develop cytotoxic activity and eliminate virus-induced tumor cells in the absence of regulatory T cells.
Cancer immunology, immunotherapy : CII
Akhmetzyanova I,Zelinskyy G,Schimmer S,Brandau S,Altenhoff P,Sparwasser T,Dittmer U
56-0041 was used in Flow cytometry/Cell sorting to explore the role of effector CD4(+) T cells in the immune control of tumours.
Fri Feb 01 00:00:00 EST 2013
A mouse model for inducible overexpression of Prdm14 results in rapid-onset and highly penetrant T-cell acute lymphoblastic leukemia (T-ALL).
Disease models & mechanisms
Carofino BL,Ayanga B,Justice MJ
Published figure using CD4 monoclonal antibody (Product # 56-0041-82) in Flow Cytometry
Fri Nov 01 00:00:00 EDT 2013
Interleukin-22 as a molecular adjuvant facilitates IL-17-producing CD8+ T cell responses against a HBV DNA vaccine in mice.
Human vaccines & immunotherapeutics
Wu B,Zou Q,Hu Y,Wang B
Published figure using CD4 monoclonal antibody (Product # 56-0041-82) in Flow Cytometry
Tue Oct 01 00:00:00 EDT 2013
The early activation marker CD69 regulates the expression of chemokines and CD4 T cell accumulation in intestine.
PloS one
Radulovic K,Rossini V,Manta C,Holzmann K,Kestler HA,Niess JH
Published figure using CD4 monoclonal antibody (Product # 56-0041-82) in Immunofluorescence
Thu Jan 23 00:00:00 EST 2014
The early activation marker CD69 regulates the expression of chemokines and CD4 T cell accumulation in intestine.
PloS one
Radulovic K,Rossini V,Manta C,Holzmann K,Kestler HA,Niess JH
Published figure using CD4 monoclonal antibody (Product # 56-0041-82) in Immunofluorescence
Thu Jan 23 00:00:00 EST 2014
Enhanced immune response against HIV-1 induced by a heterologous DNA prime-adenovirus boost vaccination using mannosylated polyethyleneimine as DNA vaccine adjuvant.
International journal of nanomedicine
Li M,Jiang Y,Xu C,Zhang Z,Sun X
Published figure using CD4 monoclonal antibody (Product # 56-0041-82) in Flow Cytometry
Wed Apr 02 00:00:00 EDT 2014
Nod2 activates NF-kB in CD4+ T cells but its expression is dispensable for T cell-induced colitis.
PloS one
Zanello G,Goethel A,Forster K,Geddes K,Philpott DJ,Croitoru K
Published figure using CD4 monoclonal antibody (Product # 56-0041-82) in Flow Cytometry
Thu Jul 31 00:00:00 EDT 2014
Developmentally regulated availability of RANKL and CD40 ligand reveals distinct mechanisms of fetal and adult cross-talk in the thymus medulla.
Journal of immunology (Baltimore, Md. : 1950)
Desanti GE,Cowan JE,Baik S,Parnell SM,White AJ,Penninger JM,Lane PJ,Jenkinson EJ,Jenkinson WE,Anderson G
56-0041 was used in Flow cytometry/Cell sorting to study how multiple hemopoietic cell types regulate mTEC development through differential provision of RANKL/CD40L during ontogeny, revealing molecular differences in foetal and adult hemopoietic cross-talk.
Sat Dec 15 00:00:00 EST 2012
The acute environment, rather than T cell subset pre-commitment, regulates expression of the human T cell cytokine amphiregulin.
PloS one
Qi Y,Operario DJ,Georas SN,Mosmann TR
56-0041 was used in Flow cytometry/Cell sorting to collate a detailed analysis of the regulation of Amphiregulin expression by human T cell subsets.
Thu Dec 13 00:00:00 EST 2012
Soluble MOG35-55/I-A(b) dimers ameliorate experimental autoimmune encephalomyelitis by reducing encephalitogenic T cells.
PloS one
Gong Y,Wang Z,Liang Z,Duan H,Ouyang L,Yu Q,Xu Z,Shen G,Weng X,Wu X
Published figure using CD4 monoclonal antibody (Product # 56-0041-82) in Flow Cytometry
Fri Jul 19 00:00:00 EDT 2013
RUNX transcription factor-mediated association of Cd4 and Cd8 enables coordinate gene regulation.
Immunity
Collins A,Hewitt SL,Chaumeil J,Sellars M,Micsinai M,Allinne J,Parisi F,Nora EP,Bolland DJ,Corcoran AE,Kluger Y,Bosselut R,Ellmeier W,Chong MM,Littman DR,Skok JA
56-0041 was used in Flow cytometry/Cell sorting to study how communication between Cd4 and Cd8 appears to enable long-range epigenetic regulation to ensure that expression of one excludes the other in mature CD4 or CD8 single-positive cells.
Fri Mar 25 00:00:00 EDT 2011
Rapamycin ameliorates dystrophic phenotype in mdx mouse skeletal muscle.
Molecular medicine (Cambridge, Mass.)
Eghtesad S,Jhunjhunwala S,Little SR,Clemens PR
Published figure using CD4 monoclonal antibody (Product # 56-0041-82) in Immunohistochemistry
Sun Mar 25 00:00:00 EDT 2012
T cell factor 1 regulates thymocyte survival via a RORγt-dependent pathway.
Journal of immunology (Baltimore, Md. : 1950)
Wang R,Xie H,Huang Z,Ma J,Fang X,Ding Y,Sun Z
Published figure using CD4 monoclonal antibody (Product # 56-0041-82) in Flow Cytometry
Thu Dec 01 00:00:00 EST 2011
Effects of irradiating adult mdx mice before full-length dystrophin cDNA transfer on host anti-dystrophin immunity.
Gene therapy
Eghtesad S,Zheng H,Nakai H,Epperly MW,Clemens PR
Published figure using CD4 monoclonal antibody (Product # 56-0041-82) in Immunohistochemistry
Wed Sep 01 00:00:00 EDT 2010
Down-regulation of Gfi-1 expression by TGF-beta is important for differentiation of Th17 and CD103+ inducible regulatory T cells.
The Journal of experimental medicine
Zhu J,Davidson TS,Wei G,Jankovic D,Cui K,Schones DE,Guo L,Zhao K,Shevach EM,Paul WE
56-0041 was used in Flow cytometry/Cell sorting to show that Gfi-1, a transcriptional repressor, has a critical role in enhancing Th2 cell expansion and repressing induction of Th17 and CD103(+) iTreg cells.
Mon Feb 16 00:00:00 EST 2009
Tracking epitope-specific T cells.
Nature protocols
Moon JJ,Chu HH,Hataye J,Pagán AJ,Pepper M,McLachlan JB,Zell T,Jenkins MK
56-0041 was used in Flow cytometry/Cell sorting to track epitope-specific T cells.
Tue Jun 30 00:00:00 EDT 2009
Suppression of alkali burn-induced corneal neovascularization by dendritic cell vaccination targeting VEGF receptor 2.
Investigative ophthalmology & visual science
Mochimaru H,Usui T,Yaguchi T,Nagahama Y,Hasegawa G,Usui Y,Shimmura S,Tsubota K,Amano S,Kawakami Y,Ishida S
Thu May 01 00:00:00 EDT 2008
Myocardial infarct-sparing effect of adenosine A2A receptor activation is due to its action on CD4+ T lymphocytes.
Circulation
Yang Z,Day YJ,Toufektsian MC,Xu Y,Ramos SI,Marshall MA,French BA,Linden J
Tue Nov 07 00:00:00 EST 2006
Runx3 and Runx1 are required for CD8 T cell development during thymopoiesis.
Proceedings of the National Academy of Sciences of the United States of America
Woolf E,Xiao C,Fainaru O,Lotem J,Rosen D,Negreanu V,Bernstein Y,Goldenberg D,Brenner O,Berke G,Levanon D,Groner Y
Published figure using CD4 monoclonal antibody (Product # 56-0041-82) in Flow Cytometry
Tue Jun 24 00:00:00 EDT 2003